1GKNA

Structure determination and rational mutagenesis reveal binding surface of immune adherence receptor, cr1 (cd35)
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
128
structure length
128
Chain Sequence
EAEAHCQAPDHFLFAKLKTQTTASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRITYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the C3B Binding Site of Cr1 (Cd35), the Immune Adherence Receptor
pubmed doi rcsb
molecule tags Complement
source organism Homo sapiens
molecule keywords COMPLEMENT RECEPTOR TYPE 1
total genus 14
structure length 128
sequence length 128
ec nomenclature
pdb deposition date 2001-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1gknA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1gknA02
1E8BA 3OXUD 4FXGG 3KZJA 1HFHA 2B5ID 2IZ4A 3R62A 4AYEA 1GPZA 3T5OA 1UOTP 2UWNA 4J38B 1CKLA 2JGWA 4WJG2 1C1ZA 2CG7A 2CG6A 3RJ3D 4AYDA 4MUCA 1H04P 2XRDA 3O8EB 4K12A 4C16A 2ERJA 3IU3I 1HFIA 3EJHA 1QUBA 2JRAA 2RLPA 2RLQA 2XQWC 2RKZA 1QGBA 4KKDA 2WIIC 1O9AA 2RKYA 1H2PP 3KXVA 5FO8C 5JPMG 1E88A 2YBYA 2W81A 4F4OC 4ZH1D 1G4GA 2LOJA 3TVJA 3ZD2A 1NWVA 2CKUA 2EC3A 1OK1A 5I0QB 2KMSA 4B2RA 2YRAA 2MCYA 1SS2A 3NFPI 2MCZA 3IX0A 3M7PA 5HYPA 1GKNA 2QY0A 1QO6A 3OP8A 5HYUB 2XRBA 3SW0X 1OK9A 1TPMA 2W80A 1U5MA 2A55A 1FBRA 2G7IA 3GXEA 2BZMA 4A5WB 1GHQB 4LOTA 1VVCA 1H03P 1OJYA 3ERBA 3ZD1A 1TPGA 1VVDA 1ZJKA 1SRZA 2XWBF 3GOVA 3MQLA 1OJWA 2KRIA 4PZ5A 3INBC 2IZ3A 1OJVA 4LOSA 4CSYA 1G4FA 1PPQA 2RL0A 4ONTD 1H2QP 2V8EA 2O39C 2EHFA 1GKGA 2JGXA 4IGDA 4DJZA 1HCCA 1Z92B 1OK2A 1LY2A 1E5GA 1MD8A 1Q3XA 4JHSA 1TPNA 4YNXA 3ZRZA 5HYTB 5HZPB 1MD7A 1OK3A 3CALA 4AYIA 3L89M 3OEDC 4AYMA 2XWJI 1ELVA 4B2SA
chains in the Genus database with same CATH superfamily
1E8BA 3OXUD 4FXGG 3KZJA 2I2LA 1HFHA 2B5ID 2IZ4A 3R62A 4AYEA 1GPZA 3T5OA 1UOTP 2UWNA 4J38B 3WSYA 1CKLA 2JGWA 4PO7A 1C1ZA 2CG7A 2CG6A 4WJG2 3RJ3D 4AYDA 4MUCA 1H04P 2XRDA 3O8EB 4K12A 4C16A 2ERJA 3IU3I 1HFIA 3EJHA 1QUBA 3ZLDA 2JRAA 2RLPA 4MSLA 2RLQA 2XQWC 2RKZA 2Y8RA 1QGBA 4KKDA 2WIIC 3FGRA 1O9AA 2RKYA 3ZLEA 1H2PP 2X2ZA 3KXVA 4APLA 5FO8C 5JPMG 1E88A 2YBYA 3VWOA 2W81A 4F4OC 4ZH1D 1G4GA 2LOJA 4YIZA 3TVJA 3ZD2A 1NWVA 2CKUA 3WSXA 2EC3A 1OK1A 1RLHA 5I0QB 2KMSA 4B2RA 2YRAA 2MCYA 1SS2A 5DN5A 3NFPI 2MCZA 3IX0A 3M7PA 5HYPA 1GKNA 3F6KA 4N7EA 2QY0A 1QO6A 3OP8A 2ZYCA 5HYUB 2XRBA 3SW0X 1OK9A 1TPMA 2W80A 1U5MA 2A55A 1FBRA 2G7IA 3GXEA 2BZMA 4A5WB 1GHQB 4LOTA 1VVCA 1H03P 1OJYA 3ERBA 3ZD1A 1TPGA 3K3TA 1VVDA 1ZJKA 1SRZA 2XWBF 2Y8TA 3GOVA 3MQLA 5DN4A 1OJWA 2KRIA 4PZ5A 3INBC 2IZ3A 1OJVA 4LOSA 4CSYA 1G4FA 2Y8SA 3FGTA 1PPQA 2RL0A 4ONTD 1H2QP 2V8EA 2O39C 2EHFA 3NJAA 1GKGA 2JGXA 4IGDA 4DJZA 1HCCA 1Z92B 1OK2A 1LY2A 1E5GA 1MD8A 1Q3XA 4JHSA 1TPNA 4YNXA 3ZRZA 5HYTB 5HZPB 3CI0J 1MD7A 1OK3A 3CALA 4AYIA 3L89M 3OEDC 4BWCA 4AYMA 2XWJI 1ELVA 4B2SA
chains in the Genus database with same CATH topology
1E8BA 3OXUD 4FXGG 3KZJA 1HFHA 2B5ID 2IZ4A 3R62A 4AYEA 1GPZA 3T5OA 1UOTP 2UWNA 4J38B 1CKLA 2JGWA 4WJG2 1C1ZA 2CG7A 2CG6A 3RJ3D 4AYDA 4MUCA 1H04P 2XRDA 3O8EB 4K12A 4C16A 2ERJA 3IU3I 1HFIA 3EJHA 1QUBA 2JRAA 2RLPA 2RLQA 2XQWC 2RKZA 1QGBA 4KKDA 2WIIC 1O9AA 2RKYA 1H2PP 3KXVA 5FO8C 5JPMG 1E88A 2YBYA 2W81A 4F4OC 4ZH1D 1G4GA 2LOJA 3TVJA 3ZD2A 1NWVA 2CKUA 2EC3A 1OK1A 5I0QB 2KMSA 4B2RA 2YRAA 2MCYA 1SS2A 3NFPI 2MCZA 3IX0A 3M7PA 5HYPA 1GKNA 2QY0A 1QO6A 3OP8A 5HYUB 2XRBA 3SW0X 1OK9A 1TPMA 2W80A 1U5MA 2A55A 1FBRA 2G7IA 3GXEA 2BZMA 4A5WB 1GHQB 4LOTA 1VVCA 1H03P 1OJYA 3ERBA 3ZD1A 1TPGA 1VVDA 1ZJKA 1SRZA 2XWBF 3GOVA 3MQLA 1OJWA 2KRIA 4PZ5A 3INBC 2IZ3A 1OJVA 4LOSA 4CSYA 1G4FA 1PPQA 2RL0A 4ONTD 1H2QP 2V8EA 2O39C 2EHFA 1GKGA 2JGXA 4IGDA 4DJZA 1HCCA 1Z92B 1OK2A 1LY2A 1E5GA 1MD8A 1Q3XA 4JHSA 1TPNA 4YNXA 3ZRZA 5HYTB 5HZPB 1MD7A 1OK3A 3CALA 4AYIA 3L89M 3OEDC 4AYMA 2XWJI 1ELVA 4B2SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E8B A;  3OXU D;  4FXG G;  3KZJ A;  1HFH A;  2B5I D;  2IZ4 A;  3R62 A;  4AYE A;  1GPZ A;  3T5O A;  1UOT P;  2UWN A;  4J38 B;  1CKL A;  2JGW A;  4WJG 2;  1C1Z A;  2CG7 A;  2CG6 A;  3RJ3 D;  4AYD A;  4MUC A;  1H04 P;  2XRD A;  3O8E B;  4K12 A;  4C16 A;  2ERJ A;  3IU3 I;  1HFI A;  3EJH A;  1QUB A;  2JRA A;  2RLP A;  2RLQ A;  2XQW C;  2RKZ A;  1QGB A;  4KKD A;  2WII C;  1O9A A;  2RKY A;  1H2P P;  3KXV A;  5FO8 C;  5JPM G;  1E88 A;  2YBY A;  2W81 A;  4F4O C;  4ZH1 D;  1G4G A;  2LOJ A;  3TVJ A;  3ZD2 A;  1NWV A;  2CKU A;  2EC3 A;  1OK1 A;  5I0Q B;  2KMS A;  4B2R A;  2YRA A;  2MCY A;  1SS2 A;  3NFP I;  2MCZ A;  3IX0 A;  3M7P A;  5HYP A;  1GKN A;  2QY0 A;  1QO6 A;  3OP8 A;  5HYU B;  2XRB A;  3SW0 X;  1OK9 A;  1TPM A;  2W80 A;  1U5M A;  2A55 A;  1FBR A;  2G7I A;  3GXE A;  2BZM A;  4A5W B;  1GHQ B;  4LOT A;  1VVC A;  1H03 P;  1OJY A;  3ERB A;  3ZD1 A;  1TPG A;  1VVD A;  1ZJK A;  1SRZ A;  2XWB F;  3GOV A;  3MQL A;  1OJW A;  2KRI A;  4PZ5 A;  3INB C;  2IZ3 A;  1OJV A;  4LOS A;  4CSY A;  1G4F A;  1PPQ A;  2RL0 A;  4ONT D;  1H2Q P;  2V8E A;  2O39 C;  2EHF A;  1GKG A;  2JGX A;  4IGD A;  4DJZ A;  1HCC A;  1Z92 B;  1OK2 A;  1LY2 A;  1E5G A;  1MD8 A;  1Q3X A;  4JHS A;  1TPN A;  4YNX A;  3ZRZ A;  5HYT B;  5HZP B;  1MD7 A;  1OK3 A;  3CAL A;  4AYI A;  3L89 M;  3OED C;  4AYM A;  2XWJ I;  1ELV A;  4B2S A; 
#chains in the Genus database with same CATH topology
 1E8B A;  3OXU D;  4FXG G;  3KZJ A;  2I2L A;  1HFH A;  2B5I D;  2IZ4 A;  3R62 A;  4AYE A;  1GPZ A;  3T5O A;  1UOT P;  2UWN A;  4J38 B;  3WSY A;  1CKL A;  2JGW A;  4PO7 A;  1C1Z A;  2CG7 A;  2CG6 A;  4WJG 2;  3RJ3 D;  4AYD A;  4MUC A;  1H04 P;  2XRD A;  3O8E B;  4K12 A;  4C16 A;  2ERJ A;  3IU3 I;  1HFI A;  3EJH A;  1QUB A;  3ZLD A;  2JRA A;  2RLP A;  4MSL A;  2RLQ A;  2XQW C;  2RKZ A;  2Y8R A;  1QGB A;  4KKD A;  2WII C;  3FGR A;  1O9A A;  2RKY A;  3ZLE A;  1H2P P;  2X2Z A;  3KXV A;  4APL A;  5FO8 C;  5JPM G;  1E88 A;  2YBY A;  3VWO A;  2W81 A;  4F4O C;  4ZH1 D;  1G4G A;  2LOJ A;  4YIZ A;  3TVJ A;  3ZD2 A;  1NWV A;  2CKU A;  3WSX A;  2EC3 A;  1OK1 A;  1RLH A;  5I0Q B;  2KMS A;  4B2R A;  2YRA A;  2MCY A;  1SS2 A;  5DN5 A;  3NFP I;  2MCZ A;  3IX0 A;  3M7P A;  5HYP A;  1GKN A;  3F6K A;  4N7E A;  2QY0 A;  1QO6 A;  3OP8 A;  2ZYC A;  5HYU B;  2XRB A;  3SW0 X;  1OK9 A;  1TPM A;  2W80 A;  1U5M A;  2A55 A;  1FBR A;  2G7I A;  3GXE A;  2BZM A;  4A5W B;  1GHQ B;  4LOT A;  1VVC A;  1H03 P;  1OJY A;  3ERB A;  3ZD1 A;  1TPG A;  3K3T A;  1VVD A;  1ZJK A;  1SRZ A;  2XWB F;  2Y8T A;  3GOV A;  3MQL A;  5DN4 A;  1OJW A;  2KRI A;  4PZ5 A;  3INB C;  2IZ3 A;  1OJV A;  4LOS A;  4CSY A;  1G4F A;  2Y8S A;  3FGT A;  1PPQ A;  2RL0 A;  4ONT D;  1H2Q P;  2V8E A;  2O39 C;  2EHF A;  3NJA A;  1GKG A;  2JGX A;  4IGD A;  4DJZ A;  1HCC A;  1Z92 B;  1OK2 A;  1LY2 A;  1E5G A;  1MD8 A;  1Q3X A;  4JHS A;  1TPN A;  4YNX A;  3ZRZ A;  5HYT B;  5HZP B;  3CI0 J;  1MD7 A;  1OK3 A;  3CAL A;  4AYI A;  3L89 M;  3OED C;  4BWC A;  4AYM A;  2XWJ I;  1ELV A;  4B2S A; 
#chains in the Genus database with same CATH homology
 1E8B A;  3OXU D;  4FXG G;  3KZJ A;  1HFH A;  2B5I D;  2IZ4 A;  3R62 A;  4AYE A;  1GPZ A;  3T5O A;  1UOT P;  2UWN A;  4J38 B;  1CKL A;  2JGW A;  4WJG 2;  1C1Z A;  2CG7 A;  2CG6 A;  3RJ3 D;  4AYD A;  4MUC A;  1H04 P;  2XRD A;  3O8E B;  4K12 A;  4C16 A;  2ERJ A;  3IU3 I;  1HFI A;  3EJH A;  1QUB A;  2JRA A;  2RLP A;  2RLQ A;  2XQW C;  2RKZ A;  1QGB A;  4KKD A;  2WII C;  1O9A A;  2RKY A;  1H2P P;  3KXV A;  5FO8 C;  5JPM G;  1E88 A;  2YBY A;  2W81 A;  4F4O C;  4ZH1 D;  1G4G A;  2LOJ A;  3TVJ A;  3ZD2 A;  1NWV A;  2CKU A;  2EC3 A;  1OK1 A;  5I0Q B;  2KMS A;  4B2R A;  2YRA A;  2MCY A;  1SS2 A;  3NFP I;  2MCZ A;  3IX0 A;  3M7P A;  5HYP A;  1GKN A;  2QY0 A;  1QO6 A;  3OP8 A;  5HYU B;  2XRB A;  3SW0 X;  1OK9 A;  1TPM A;  2W80 A;  1U5M A;  2A55 A;  1FBR A;  2G7I A;  3GXE A;  2BZM A;  4A5W B;  1GHQ B;  4LOT A;  1VVC A;  1H03 P;  1OJY A;  3ERB A;  3ZD1 A;  1TPG A;  1VVD A;  1ZJK A;  1SRZ A;  2XWB F;  3GOV A;  3MQL A;  1OJW A;  2KRI A;  4PZ5 A;  3INB C;  2IZ3 A;  1OJV A;  4LOS A;  4CSY A;  1G4F A;  1PPQ A;  2RL0 A;  4ONT D;  1H2Q P;  2V8E A;  2O39 C;  2EHF A;  1GKG A;  2JGX A;  4IGD A;  4DJZ A;  1HCC A;  1Z92 B;  1OK2 A;  1LY2 A;  1E5G A;  1MD8 A;  1Q3X A;  4JHS A;  1TPN A;  4YNX A;  3ZRZ A;  5HYT B;  5HZP B;  1MD7 A;  1OK3 A;  3CAL A;  4AYI A;  3L89 M;  3OED C;  4AYM A;  2XWJ I;  1ELV A;  4B2S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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