2A55A

Solution structure of the two n-terminal ccp modules of c4b-binding protein (c4bp) alpha-chain.
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
133
structure length
133
Chain Sequence
MNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEILEHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human C4b-binding Protein, Structural Basis for Interaction with Streptococcal M Protein, a Major Bacterial Virulence Factor
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords C4b-binding protein
total genus 9
structure length 133
sequence length 133
ec nomenclature
pdb deposition date 2005-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2a55A02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2a55A01
5FO8C 5HYTB 2XRDA 2XRBA 3GXEA 2LOJA 1H04P 2RLPA 2G7IA 3KZJA 4CSYA 2RL0A 3GOVA 1GKNA 5HYUB 4KKDA 3RJ3D 1QGBA 1GPZA 1QO6A 4ZH1D 1VVCA 2JGWA 1G4GA 1OK9A 4YNXA 4DJZA 3INBC 3ERBA 2CG6A 3R62A 1MD8A 1UOTP 1LY2A 1E8BA 2O39C 3OP8A 2W81A 1HFHA 2ERJA 4PZ5A 1TPNA 2MCZA 2UWNA 5JPMG 4AYIA 3ZRZA 1CKLA 2RKZA 3MQLA 1NWVA 3ZD2A 2KMSA 1GKGA 2V8EA 4AYEA 2BZMA 1HCCA 4MUCA 3T5OA 5I0QB 1TPMA 1Z92B 3ZD1A 3L89M 3EJHA 4LOTA 1OJVA 3O8EB 1GHQB 3CALA 4A5WB 4AYDA 4AYMA 3TVJA 2JGXA 1FBRA 2XWJI 4C16A 3NFPI 1E5GA 1C1ZA 2B5ID 1MD7A 1OK1A 1QUBA 3OXUD 2YBYA 4B2RA 2RKYA 1VVDA 4LOSA 3KXVA 4JHSA 1G4FA 2IZ4A 2XQWC 1SRZA 2KRIA 2QY0A 2W80A 2YRAA 4F4OC 5HYPA 2RLQA 4K12A 1TPGA 3M7PA 1E88A 1ELVA 1O9AA 1OK2A 5HZPB 4WJG2 1H2QP 2IZ3A 1H03P 1SS2A 2CKUA 1Q3XA 2CG7A 1ZJKA 4FXGG 2XWBF 4J38B 3SW0X 3IU3I 2EC3A 4B2SA 1PPQA 1OK3A 2EHFA 1H2PP 4IGDA 4ONTD 1HFIA 2A55A 2JRAA 3IX0A 2MCYA 3OEDC 2WIIC 1OJWA 1OJYA 1U5MA
chains in the Genus database with same CATH superfamily
5FO8C 5HYTB 2XRDA 2XRBA 3GXEA 2I2LA 2LOJA 1H04P 2ZYCA 2RLPA 2G7IA 3KZJA 4CSYA 2RL0A 3GOVA 1GKNA 1RLHA 5HYUB 4KKDA 3RJ3D 3FGRA 1QGBA 3F6KA 4MSLA 1GPZA 1QO6A 4ZH1D 1VVCA 2JGWA 1G4GA 1OK9A 3ZLDA 4YNXA 4DJZA 3INBC 3ERBA 2CG6A 2Y8SA 1MD8A 3R62A 1UOTP 1LY2A 1E8BA 2O39C 3OP8A 2W81A 4BWCA 1HFHA 2ERJA 4PZ5A 1TPNA 2MCZA 2UWNA 5JPMG 4AYIA 3ZRZA 3FGTA 1CKLA 2RKZA 5DN5A 3MQLA 4APLA 4PO7A 1NWVA 3ZD2A 5DN4A 2KMSA 1GKGA 3WSYA 2V8EA 4AYEA 2BZMA 1HCCA 4MUCA 3T5OA 2X2ZA 5I0QB 1TPMA 1Z92B 3ZD1A 3L89M 3EJHA 4LOTA 1OJVA 3O8EB 1GHQB 3CALA 4A5WB 3WSXA 4AYDA 4AYMA 3TVJA 2JGXA 1FBRA 3K3TA 2XWJI 4C16A 3ZLEA 3NFPI 1E5GA 1C1ZA 2B5ID 1MD7A 1OK1A 1QUBA 3OXUD 2YBYA 3NJAA 4YIZA 4B2RA 2RKYA 1VVDA 4LOSA 3KXVA 4JHSA 1G4FA 2IZ4A 2XQWC 1SRZA 2KRIA 2QY0A 2W80A 2YRAA 4F4OC 5HYPA 4N7EA 2RLQA 4K12A 1TPGA 3M7PA 1E88A 1ELVA 1O9AA 1OK2A 5HZPB 4WJG2 1H2QP 2IZ3A 1H03P 1SS2A 2CKUA 1Q3XA 2CG7A 2Y8TA 3VWOA 1ZJKA 4FXGG 2XWBF 4J38B 2Y8RA 3SW0X 3IU3I 2EC3A 4B2SA 1PPQA 1OK3A 2EHFA 1H2PP 4IGDA 4ONTD 1HFIA 2A55A 3CI0J 2JRAA 3IX0A 2MCYA 3OEDC 2WIIC 1OJWA 1OJYA 1U5MA
chains in the Genus database with same CATH topology
5FO8C 5HYTB 2XRDA 2XRBA 3GXEA 2LOJA 1H04P 2RLPA 2G7IA 3KZJA 4CSYA 2RL0A 3GOVA 1GKNA 5HYUB 4KKDA 3RJ3D 1QGBA 1GPZA 1QO6A 4ZH1D 1VVCA 2JGWA 1G4GA 1OK9A 4YNXA 4DJZA 3INBC 3ERBA 2CG6A 3R62A 1MD8A 1UOTP 1LY2A 1E8BA 2O39C 3OP8A 2W81A 1HFHA 2ERJA 4PZ5A 1TPNA 2MCZA 2UWNA 5JPMG 4AYIA 3ZRZA 1CKLA 2RKZA 3MQLA 1NWVA 3ZD2A 2KMSA 1GKGA 2V8EA 4AYEA 2BZMA 1HCCA 4MUCA 3T5OA 5I0QB 1TPMA 1Z92B 3ZD1A 3L89M 3EJHA 4LOTA 1OJVA 3O8EB 1GHQB 3CALA 4A5WB 4AYDA 4AYMA 3TVJA 2JGXA 1FBRA 2XWJI 4C16A 3NFPI 1E5GA 1C1ZA 2B5ID 1MD7A 1OK1A 1QUBA 3OXUD 2YBYA 4B2RA 2RKYA 1VVDA 4LOSA 3KXVA 4JHSA 1G4FA 2IZ4A 2XQWC 1SRZA 2KRIA 2QY0A 2W80A 2YRAA 4F4OC 5HYPA 2RLQA 4K12A 1TPGA 3M7PA 1E88A 1ELVA 1O9AA 1OK2A 5HZPB 4WJG2 1H2QP 2IZ3A 1H03P 1SS2A 2CKUA 1Q3XA 2CG7A 1ZJKA 4FXGG 2XWBF 4J38B 3SW0X 3IU3I 2EC3A 4B2SA 1PPQA 1OK3A 2EHFA 1H2PP 4IGDA 4ONTD 1HFIA 2A55A 2JRAA 3IX0A 2MCYA 3OEDC 2WIIC 1OJWA 1OJYA 1U5MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FO8 C;  5HYT B;  2XRD A;  2XRB A;  3GXE A;  2LOJ A;  1H04 P;  2RLP A;  2G7I A;  3KZJ A;  4CSY A;  2RL0 A;  3GOV A;  1GKN A;  5HYU B;  4KKD A;  3RJ3 D;  1QGB A;  1GPZ A;  1QO6 A;  4ZH1 D;  1VVC A;  2JGW A;  1G4G A;  1OK9 A;  4YNX A;  4DJZ A;  3INB C;  3ERB A;  2CG6 A;  3R62 A;  1MD8 A;  1UOT P;  1LY2 A;  1E8B A;  2O39 C;  3OP8 A;  2W81 A;  1HFH A;  2ERJ A;  4PZ5 A;  1TPN A;  2MCZ A;  2UWN A;  5JPM G;  4AYI A;  3ZRZ A;  1CKL A;  2RKZ A;  3MQL A;  1NWV A;  3ZD2 A;  2KMS A;  1GKG A;  2V8E A;  4AYE A;  2BZM A;  1HCC A;  4MUC A;  3T5O A;  5I0Q B;  1TPM A;  1Z92 B;  3ZD1 A;  3L89 M;  3EJH A;  4LOT A;  1OJV A;  3O8E B;  1GHQ B;  3CAL A;  4A5W B;  4AYD A;  4AYM A;  3TVJ A;  2JGX A;  1FBR A;  2XWJ I;  4C16 A;  3NFP I;  1E5G A;  1C1Z A;  2B5I D;  1MD7 A;  1OK1 A;  1QUB A;  3OXU D;  2YBY A;  4B2R A;  2RKY A;  1VVD A;  4LOS A;  3KXV A;  4JHS A;  1G4F A;  2IZ4 A;  2XQW C;  1SRZ A;  2KRI A;  2QY0 A;  2W80 A;  2YRA A;  4F4O C;  5HYP A;  2RLQ A;  4K12 A;  1TPG A;  3M7P A;  1E88 A;  1ELV A;  1O9A A;  1OK2 A;  5HZP B;  4WJG 2;  1H2Q P;  2IZ3 A;  1H03 P;  1SS2 A;  2CKU A;  1Q3X A;  2CG7 A;  1ZJK A;  4FXG G;  2XWB F;  4J38 B;  3SW0 X;  3IU3 I;  2EC3 A;  4B2S A;  1PPQ A;  1OK3 A;  2EHF A;  1H2P P;  4IGD A;  4ONT D;  1HFI A;  2A55 A;  2JRA A;  3IX0 A;  2MCY A;  3OED C;  2WII C;  1OJW A;  1OJY A;  1U5M A; 
#chains in the Genus database with same CATH topology
 5FO8 C;  5HYT B;  2XRD A;  2XRB A;  3GXE A;  2I2L A;  2LOJ A;  1H04 P;  2ZYC A;  2RLP A;  2G7I A;  3KZJ A;  4CSY A;  2RL0 A;  3GOV A;  1GKN A;  1RLH A;  5HYU B;  4KKD A;  3RJ3 D;  3FGR A;  1QGB A;  3F6K A;  4MSL A;  1GPZ A;  1QO6 A;  4ZH1 D;  1VVC A;  2JGW A;  1G4G A;  1OK9 A;  3ZLD A;  4YNX A;  4DJZ A;  3INB C;  3ERB A;  2CG6 A;  2Y8S A;  1MD8 A;  3R62 A;  1UOT P;  1LY2 A;  1E8B A;  2O39 C;  3OP8 A;  2W81 A;  4BWC A;  1HFH A;  2ERJ A;  4PZ5 A;  1TPN A;  2MCZ A;  2UWN A;  5JPM G;  4AYI A;  3ZRZ A;  3FGT A;  1CKL A;  2RKZ A;  5DN5 A;  3MQL A;  4APL A;  4PO7 A;  1NWV A;  3ZD2 A;  5DN4 A;  2KMS A;  1GKG A;  3WSY A;  2V8E A;  4AYE A;  2BZM A;  1HCC A;  4MUC A;  3T5O A;  2X2Z A;  5I0Q B;  1TPM A;  1Z92 B;  3ZD1 A;  3L89 M;  3EJH A;  4LOT A;  1OJV A;  3O8E B;  1GHQ B;  3CAL A;  4A5W B;  3WSX A;  4AYD A;  4AYM A;  3TVJ A;  2JGX A;  1FBR A;  3K3T A;  2XWJ I;  4C16 A;  3ZLE A;  3NFP I;  1E5G A;  1C1Z A;  2B5I D;  1MD7 A;  1OK1 A;  1QUB A;  3OXU D;  2YBY A;  3NJA A;  4YIZ A;  4B2R A;  2RKY A;  1VVD A;  4LOS A;  3KXV A;  4JHS A;  1G4F A;  2IZ4 A;  2XQW C;  1SRZ A;  2KRI A;  2QY0 A;  2W80 A;  2YRA A;  4F4O C;  5HYP A;  4N7E A;  2RLQ A;  4K12 A;  1TPG A;  3M7P A;  1E88 A;  1ELV A;  1O9A A;  1OK2 A;  5HZP B;  4WJG 2;  1H2Q P;  2IZ3 A;  1H03 P;  1SS2 A;  2CKU A;  1Q3X A;  2CG7 A;  2Y8T A;  3VWO A;  1ZJK A;  4FXG G;  2XWB F;  4J38 B;  2Y8R A;  3SW0 X;  3IU3 I;  2EC3 A;  4B2S A;  1PPQ A;  1OK3 A;  2EHF A;  1H2P P;  4IGD A;  4ONT D;  1HFI A;  2A55 A;  3CI0 J;  2JRA A;  3IX0 A;  2MCY A;  3OED C;  2WII C;  1OJW A;  1OJY A;  1U5M A; 
#chains in the Genus database with same CATH homology
 5FO8 C;  5HYT B;  2XRD A;  2XRB A;  3GXE A;  2LOJ A;  1H04 P;  2RLP A;  2G7I A;  3KZJ A;  4CSY A;  2RL0 A;  3GOV A;  1GKN A;  5HYU B;  4KKD A;  3RJ3 D;  1QGB A;  1GPZ A;  1QO6 A;  4ZH1 D;  1VVC A;  2JGW A;  1G4G A;  1OK9 A;  4YNX A;  4DJZ A;  3INB C;  3ERB A;  2CG6 A;  3R62 A;  1MD8 A;  1UOT P;  1LY2 A;  1E8B A;  2O39 C;  3OP8 A;  2W81 A;  1HFH A;  2ERJ A;  4PZ5 A;  1TPN A;  2MCZ A;  2UWN A;  5JPM G;  4AYI A;  3ZRZ A;  1CKL A;  2RKZ A;  3MQL A;  1NWV A;  3ZD2 A;  2KMS A;  1GKG A;  2V8E A;  4AYE A;  2BZM A;  1HCC A;  4MUC A;  3T5O A;  5I0Q B;  1TPM A;  1Z92 B;  3ZD1 A;  3L89 M;  3EJH A;  4LOT A;  1OJV A;  3O8E B;  1GHQ B;  3CAL A;  4A5W B;  4AYD A;  4AYM A;  3TVJ A;  2JGX A;  1FBR A;  2XWJ I;  4C16 A;  3NFP I;  1E5G A;  1C1Z A;  2B5I D;  1MD7 A;  1OK1 A;  1QUB A;  3OXU D;  2YBY A;  4B2R A;  2RKY A;  1VVD A;  4LOS A;  3KXV A;  4JHS A;  1G4F A;  2IZ4 A;  2XQW C;  1SRZ A;  2KRI A;  2QY0 A;  2W80 A;  2YRA A;  4F4O C;  5HYP A;  2RLQ A;  4K12 A;  1TPG A;  3M7P A;  1E88 A;  1ELV A;  1O9A A;  1OK2 A;  5HZP B;  4WJG 2;  1H2Q P;  2IZ3 A;  1H03 P;  1SS2 A;  2CKU A;  1Q3X A;  2CG7 A;  1ZJK A;  4FXG G;  2XWB F;  4J38 B;  3SW0 X;  3IU3 I;  2EC3 A;  4B2S A;  1PPQ A;  1OK3 A;  2EHF A;  1H2P P;  4IGD A;  4ONT D;  1HFI A;  2A55 A;  2JRA A;  3IX0 A;  2MCY A;  3OED C;  2WII C;  1OJW A;  1OJY A;  1U5M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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