The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
11
|
sequence length |
129
|
structure length |
129
|
Chain Sequence |
EAEFGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure.
pubmed doi rcsb |
| molecule keywords |
COMPLEMENT FACTOR H
|
| molecule tags |
Immune system
|
| source organism |
Homo sapiens
|
| total genus |
11
|
| structure length |
129
|
| sequence length |
129
|
| ec nomenclature | |
| pdb deposition date | 2005-08-18 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00084 | Sushi | Sushi repeat (SCR repeat) |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Ribbon | Complement Module; domain 1 | Complement Module, domain 1 | ||
| Mainly Beta | Ribbon | Complement Module; domain 1 | Complement Module, domain 1 |
#chains in the Genus database with same CATH superfamily 2EHF A; 2MCY A; 3SW0 X; 2RKY A; 2XRB A; 3ZRZ A; 2UWN A; 2JGW A; 2G7I A; 1MD8 A; 4C16 A; 1HFI A; 4PZ5 A; 1C1Z A; 1TPN A; 4AYE A; 1E5G A; 2XRD A; 5HYP A; 3RJ3 D; 1ZJK A; 2CG7 A; 5FO8 C; 1MD7 A; 4B2S A; 3ERB A; 4F4O C; 1OJY A; 1OK9 A; 1LY2 A; 3T5O A; 4AYM A; 2JGX A; 4ZH1 D; 1GKG A; 1UOT P; 1Q3X A; 1FBR A; 2MCZ A; 1H03 P; 1OK2 A; 4IGD A; 2RLP A; 2O39 C; 1HFH A; 1ELV A; 3R62 A; 4LOT A; 1G4G A; 3TVJ A; 4KKD A; 2EC3 A; 5I0Q B; 3L89 M; 3OP8 A; 1QO6 A; 4YNX A; 2BZM A; 2CKU A; 3ZD1 A; 1Z92 B; 1TPG A; 1GPZ A; 2IZ4 A; 1O9A A; 5JPM G; 4B2R A; 2W81 A; 1VVC A; 5HYU B; 4ONT D; 4CSY A; 4JHS A; 1U5M A; 1SRZ A; 2LOJ A; 4AYD A; 2XWJ I; 3O8E B; 3KZJ A; 3MQL A; 1H04 P; 1TPM A; 4MUC A; 4LOS A; 2XQW C; 1H2Q P; 2JRA A; 1OK1 A; 1OJV A; 4FXG G; 1QUB A; 3OED C; 3IX0 A; 1VVD A; 4J38 B; 2RLQ A; 2B5I D; 4DJZ A; 3ZD2 A; 1SS2 A; 3INB C; 2V8E A; 1OJW A; 3GXE A; 3KXV A; 2QY0 A; 3EJH A; 2A55 A; 1HCC A; 2WII C; 3IU3 I; 2KRI A; 1QGB A; 5HZP B; 2W80 A; 2CG6 A; 4A5W B; 1NWV A; 1GHQ B; 1E8B A; 2RL0 A; 2XWB F; 2YRA A; 3CAL A; 2KMS A; 1PPQ A; 4K12 A; 2IZ3 A; 1E88 A; 5HYT B; 1G4F A; 1CKL A; 3GOV A; 2RKZ A; 4AYI A; 3M7P A; 3OXU D; 2ERJ A; 2YBY A; 1H2P P; 3NFP I; 1GKN A; 1OK3 A; 4WJG 2; #chains in the Genus database with same CATH topology 2EHF A; 2MCY A; 3SW0 X; 2RKY A; 2XRB A; 3ZRZ A; 2UWN A; 2JGW A; 3CI0 J; 2G7I A; 1MD8 A; 4C16 A; 1HFI A; 4PZ5 A; 1C1Z A; 1TPN A; 4AYE A; 5DN5 A; 1E5G A; 2XRD A; 5HYP A; 3RJ3 D; 1ZJK A; 2CG7 A; 5FO8 C; 1MD7 A; 4B2S A; 3ERB A; 4F4O C; 1OJY A; 1OK9 A; 1LY2 A; 3T5O A; 3VWO A; 2I2L A; 4AYM A; 2JGX A; 4ZH1 D; 1GKG A; 1UOT P; 1Q3X A; 2ZYC A; 1FBR A; 2MCZ A; 1H03 P; 1OK2 A; 2Y8T A; 4IGD A; 2RLP A; 2O39 C; 1HFH A; 1ELV A; 3R62 A; 5DN4 A; 4LOT A; 1G4G A; 3TVJ A; 4KKD A; 2EC3 A; 5I0Q B; 3L89 M; 3OP8 A; 1QO6 A; 4YNX A; 2BZM A; 2CKU A; 3WSY A; 3ZD1 A; 1Z92 B; 1TPG A; 1GPZ A; 2IZ4 A; 1O9A A; 5JPM G; 4B2R A; 4PO7 A; 2W81 A; 1VVC A; 5HYU B; 4ONT D; 4CSY A; 1RLH A; 4JHS A; 1U5M A; 1SRZ A; 2LOJ A; 4AYD A; 2XWJ I; 4APL A; 3O8E B; 3KZJ A; 3MQL A; 1H04 P; 1TPM A; 4MUC A; 3FGT A; 4LOS A; 2XQW C; 3FGR A; 1H2Q P; 2JRA A; 1OK1 A; 3K3T A; 1OJV A; 3F6K A; 4FXG G; 1QUB A; 3OED C; 3IX0 A; 1VVD A; 4J38 B; 2RLQ A; 2B5I D; 4DJZ A; 3ZD2 A; 4MSL A; 1SS2 A; 3INB C; 2V8E A; 1OJW A; 3GXE A; 4BWC A; 3ZLD A; 3KXV A; 2QY0 A; 3EJH A; 4YIZ A; 2A55 A; 1HCC A; 2WII C; 3IU3 I; 2KRI A; 1QGB A; 3WSX A; 5HZP B; 2W80 A; 2CG6 A; 4A5W B; 1NWV A; 1GHQ B; 1E8B A; 2RL0 A; 2XWB F; 2YRA A; 3CAL A; 2KMS A; 3NJA A; 1PPQ A; 4K12 A; 2IZ3 A; 2Y8S A; 5HYT B; 2Y8R A; 1E88 A; 1CKL A; 3GOV A; 2RKZ A; 3ZLE A; 4AYI A; 1G4F A; 3M7P A; 4N7E A; 3OXU D; 2ERJ A; 2YBY A; 1H2P P; 2X2Z A; 3NFP I; 1GKN A; 1OK3 A; 4WJG 2; #chains in the Genus database with same CATH homology 2EHF A; 2MCY A; 3SW0 X; 2RKY A; 2XRB A; 3ZRZ A; 2UWN A; 2JGW A; 2G7I A; 1MD8 A; 4C16 A; 1HFI A; 4PZ5 A; 1C1Z A; 1TPN A; 4AYE A; 1E5G A; 2XRD A; 5HYP A; 3RJ3 D; 1ZJK A; 2CG7 A; 5FO8 C; 1MD7 A; 4B2S A; 3ERB A; 4F4O C; 1OJY A; 1OK9 A; 1LY2 A; 3T5O A; 4AYM A; 2JGX A; 4ZH1 D; 1GKG A; 1UOT P; 1Q3X A; 1FBR A; 2MCZ A; 1H03 P; 1OK2 A; 4IGD A; 2RLP A; 2O39 C; 1HFH A; 1ELV A; 3R62 A; 4LOT A; 1G4G A; 3TVJ A; 4KKD A; 2EC3 A; 5I0Q B; 3L89 M; 3OP8 A; 1QO6 A; 4YNX A; 2BZM A; 2CKU A; 3ZD1 A; 1Z92 B; 1TPG A; 1GPZ A; 2IZ4 A; 1O9A A; 5JPM G; 4B2R A; 2W81 A; 1VVC A; 5HYU B; 4ONT D; 4CSY A; 4JHS A; 1U5M A; 1SRZ A; 2LOJ A; 4AYD A; 2XWJ I; 3O8E B; 3KZJ A; 3MQL A; 1H04 P; 1TPM A; 4MUC A; 4LOS A; 2XQW C; 1H2Q P; 2JRA A; 1OK1 A; 1OJV A; 4FXG G; 1QUB A; 3OED C; 3IX0 A; 1VVD A; 4J38 B; 2RLQ A; 2B5I D; 4DJZ A; 3ZD2 A; 1SS2 A; 3INB C; 2V8E A; 1OJW A; 3GXE A; 3KXV A; 2QY0 A; 3EJH A; 2A55 A; 1HCC A; 2WII C; 3IU3 I; 2KRI A; 1QGB A; 5HZP B; 2W80 A; 2CG6 A; 4A5W B; 1NWV A; 1GHQ B; 1E8B A; 2RL0 A; 2XWB F; 2YRA A; 3CAL A; 2KMS A; 1PPQ A; 4K12 A; 2IZ3 A; 1E88 A; 5HYT B; 1G4F A; 1CKL A; 3GOV A; 2RKZ A; 4AYI A; 3M7P A; 3OXU D; 2ERJ A; 2YBY A; 1H2P P; 3NFP I; 1GKN A; 1OK3 A; 4WJG 2;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
