2CG7A

Second and third fibronectin type i module pair (crystal form ii).
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
90
structure length
90
Chain Sequence
AEETCFDKYTGNTYRVGDTYERPKDSMIWDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Solution and Crystal Structures of a Module Pair from the Staphylococcus Aureus-Binding Site of Human Fibronectin-A Tale with a Twist.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords FIBRONECTIN
total genus 22
structure length 90
sequence length 90
ec nomenclature
pdb deposition date 2006-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00039 fn1 Fibronectin type I domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2cg7A01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2cg7A02
5HYPA 1OK9A 3RJ3D 1E88A 2W80A 2V8EA 1H04P 2CKUA 1OJWA 2UWNA 3M7PA 3KZJA 2A55A 4KKDA 4MUCA 1SRZA 3OEDC 1PPQA 3GXEA 3ERBA 3INBC 2ERJA 1H03P 4WJG2 4B2RA 2XRDA 1SS2A 1QO6A 1VVCA 2RKZA 3IX0A 5HYTB 2RLPA 4DJZA 3ZD1A 3IU3I 3ZRZA 4IGDA 1UOTP 4F4OC 2O39C 4LOSA 4JHSA 1ZJKA 2EC3A 4A5WB 1LY2A 1G4GA 4B2SA 2KRIA 1C1ZA 2IZ4A 2RL0A 2MCZA 2KMSA 4ZH1D 1H2PP 1QGBA 3L89M 3ZD2A 2G7IA 2JRAA 1HFIA 2RLQA 2CG7A 4K12A 1FBRA 1QUBA 3O8EB 3OXUD 1GKGA 1TPNA 2RKYA 1GHQB 2XRBA 2YRAA 2LOJA 2XQWC 1OJYA 3GOVA 2WIIC 1TPMA 2XWBF 5HYUB 5JPMG 1Z92B 4J38B 1GKNA 1OK3A 4AYDA 2BZMA 1NWVA 2IZ3A 4CSYA 4ONTD 1OJVA 4LOTA 1ELVA 4YNXA 4AYEA 2JGWA 4AYIA 1TPGA 2W81A 4AYMA 1E5GA 1H2QP 3T5OA 1G4FA 2XWJI 1O9AA 1Q3XA 2JGXA 2QY0A 3OP8A 2MCYA 1MD8A 5FO8C 1CKLA 1E8BA 1HFHA 1VVDA 3EJHA 3NFPI 5HZPB 4PZ5A 5I0QB 1MD7A 3MQLA 4C16A 1HCCA 1GPZA 3TVJA 2YBYA 1U5MA 3KXVA 2B5ID 1OK1A 2CG6A 4FXGG 2EHFA 3R62A 3SW0X 1OK2A 3CALA
chains in the Genus database with same CATH superfamily
5HYPA 1OK9A 3RJ3D 1E88A 2W80A 2V8EA 1H04P 2CKUA 1OJWA 2UWNA 3M7PA 3KZJA 2A55A 4KKDA 4MUCA 1SRZA 3OEDC 1PPQA 3GXEA 3ERBA 4YIZA 3INBC 4PO7A 2ERJA 1H03P 4N7EA 4WJG2 4B2RA 2XRDA 1SS2A 1QO6A 1VVCA 2RKZA 3IX0A 2X2ZA 5HYTB 2RLPA 4DJZA 3ZD1A 3IU3I 3VWOA 4IGDA 1UOTP 3ZRZA 4F4OC 2O39C 2Y8RA 4LOSA 4JHSA 1ZJKA 2EC3A 3NJAA 4A5WB 2ZYCA 4APLA 2I2LA 1LY2A 1G4GA 4B2SA 2KRIA 1C1ZA 2IZ4A 2RL0A 2MCZA 2KMSA 4ZH1D 1H2PP 4BWCA 1QGBA 3L89M 2Y8TA 3ZD2A 2G7IA 2JRAA 1HFIA 2RLQA 3FGRA 2CG7A 4K12A 1FBRA 1QUBA 5DN5A 3O8EB 3OXUD 1GKGA 1TPNA 3CI0J 2RKYA 1GHQB 2XRBA 2YRAA 2LOJA 2XQWC 1OJYA 3GOVA 2WIIC 1TPMA 2XWBF 5HYUB 5JPMG 1Z92B 4J38B 1GKNA 1OK3A 4AYDA 2BZMA 3K3TA 1RLHA 3WSYA 1NWVA 2IZ3A 4CSYA 4ONTD 3FGTA 1OJVA 4LOTA 1ELVA 4YNXA 4AYEA 2JGWA 4AYIA 1TPGA 2W81A 4AYMA 1E5GA 1H2QP 3F6KA 3T5OA 5DN4A 1G4FA 2XWJI 1O9AA 1Q3XA 2JGXA 2QY0A 3ZLDA 3OP8A 2MCYA 1MD8A 5FO8C 3ZLEA 1CKLA 1E8BA 1HFHA 1VVDA 3EJHA 4MSLA 3NFPI 5HZPB 4PZ5A 2Y8SA 1MD7A 5I0QB 3MQLA 4C16A 1HCCA 1GPZA 3TVJA 2YBYA 1U5MA 3KXVA 2B5ID 1OK1A 2CG6A 4FXGG 2EHFA 3R62A 3SW0X 1OK2A 3CALA 3WSXA
chains in the Genus database with same CATH topology
5HYPA 1OK9A 3RJ3D 1E88A 2W80A 2V8EA 1H04P 2CKUA 1OJWA 2UWNA 3M7PA 3KZJA 2A55A 4KKDA 4MUCA 1SRZA 3OEDC 1PPQA 3GXEA 3ERBA 3INBC 2ERJA 1H03P 4WJG2 4B2RA 2XRDA 1SS2A 1QO6A 1VVCA 2RKZA 3IX0A 5HYTB 2RLPA 4DJZA 3ZD1A 3IU3I 3ZRZA 4IGDA 1UOTP 4F4OC 2O39C 4LOSA 4JHSA 1ZJKA 2EC3A 4A5WB 1LY2A 1G4GA 4B2SA 2KRIA 1C1ZA 2IZ4A 2RL0A 2MCZA 2KMSA 4ZH1D 1H2PP 1QGBA 3L89M 3ZD2A 2G7IA 2JRAA 1HFIA 2RLQA 2CG7A 4K12A 1FBRA 1QUBA 3O8EB 3OXUD 1GKGA 1TPNA 2RKYA 1GHQB 2XRBA 2YRAA 2LOJA 2XQWC 1OJYA 3GOVA 2WIIC 1TPMA 2XWBF 5HYUB 5JPMG 1Z92B 4J38B 1GKNA 1OK3A 4AYDA 2BZMA 1NWVA 2IZ3A 4CSYA 4ONTD 1OJVA 4LOTA 1ELVA 4YNXA 4AYEA 2JGWA 4AYIA 1TPGA 2W81A 4AYMA 1E5GA 1H2QP 3T5OA 1G4FA 2XWJI 1O9AA 1Q3XA 2JGXA 2QY0A 3OP8A 2MCYA 1MD8A 5FO8C 1CKLA 1E8BA 1HFHA 1VVDA 3EJHA 3NFPI 5HZPB 4PZ5A 5I0QB 1MD7A 3MQLA 4C16A 1HCCA 1GPZA 3TVJA 2YBYA 1U5MA 3KXVA 2B5ID 1OK1A 2CG6A 4FXGG 2EHFA 3R62A 3SW0X 1OK2A 3CALA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HYP A;  1OK9 A;  3RJ3 D;  1E88 A;  2W80 A;  2V8E A;  1H04 P;  2CKU A;  1OJW A;  2UWN A;  3M7P A;  3KZJ A;  2A55 A;  4KKD A;  4MUC A;  1SRZ A;  3OED C;  1PPQ A;  3GXE A;  3ERB A;  3INB C;  2ERJ A;  1H03 P;  4WJG 2;  4B2R A;  2XRD A;  1SS2 A;  1QO6 A;  1VVC A;  2RKZ A;  3IX0 A;  5HYT B;  2RLP A;  4DJZ A;  3ZD1 A;  3IU3 I;  3ZRZ A;  4IGD A;  1UOT P;  4F4O C;  2O39 C;  4LOS A;  4JHS A;  1ZJK A;  2EC3 A;  4A5W B;  1LY2 A;  1G4G A;  4B2S A;  2KRI A;  1C1Z A;  2IZ4 A;  2RL0 A;  2MCZ A;  2KMS A;  4ZH1 D;  1H2P P;  1QGB A;  3L89 M;  3ZD2 A;  2G7I A;  2JRA A;  1HFI A;  2RLQ A;  2CG7 A;  4K12 A;  1FBR A;  1QUB A;  3O8E B;  3OXU D;  1GKG A;  1TPN A;  2RKY A;  1GHQ B;  2XRB A;  2YRA A;  2LOJ A;  2XQW C;  1OJY A;  3GOV A;  2WII C;  1TPM A;  2XWB F;  5HYU B;  5JPM G;  1Z92 B;  4J38 B;  1GKN A;  1OK3 A;  4AYD A;  2BZM A;  1NWV A;  2IZ3 A;  4CSY A;  4ONT D;  1OJV A;  4LOT A;  1ELV A;  4YNX A;  4AYE A;  2JGW A;  4AYI A;  1TPG A;  2W81 A;  4AYM A;  1E5G A;  1H2Q P;  3T5O A;  1G4F A;  2XWJ I;  1O9A A;  1Q3X A;  2JGX A;  2QY0 A;  3OP8 A;  2MCY A;  1MD8 A;  5FO8 C;  1CKL A;  1E8B A;  1HFH A;  1VVD A;  3EJH A;  3NFP I;  5HZP B;  4PZ5 A;  5I0Q B;  1MD7 A;  3MQL A;  4C16 A;  1HCC A;  1GPZ A;  3TVJ A;  2YBY A;  1U5M A;  3KXV A;  2B5I D;  1OK1 A;  2CG6 A;  4FXG G;  2EHF A;  3R62 A;  3SW0 X;  1OK2 A;  3CAL A; 
#chains in the Genus database with same CATH topology
 5HYP A;  1OK9 A;  3RJ3 D;  1E88 A;  2W80 A;  2V8E A;  1H04 P;  2CKU A;  1OJW A;  2UWN A;  3M7P A;  3KZJ A;  2A55 A;  4KKD A;  4MUC A;  1SRZ A;  3OED C;  1PPQ A;  3GXE A;  3ERB A;  4YIZ A;  3INB C;  4PO7 A;  2ERJ A;  1H03 P;  4N7E A;  4WJG 2;  4B2R A;  2XRD A;  1SS2 A;  1QO6 A;  1VVC A;  2RKZ A;  3IX0 A;  2X2Z A;  5HYT B;  2RLP A;  4DJZ A;  3ZD1 A;  3IU3 I;  3VWO A;  4IGD A;  1UOT P;  3ZRZ A;  4F4O C;  2O39 C;  2Y8R A;  4LOS A;  4JHS A;  1ZJK A;  2EC3 A;  3NJA A;  4A5W B;  2ZYC A;  4APL A;  2I2L A;  1LY2 A;  1G4G A;  4B2S A;  2KRI A;  1C1Z A;  2IZ4 A;  2RL0 A;  2MCZ A;  2KMS A;  4ZH1 D;  1H2P P;  4BWC A;  1QGB A;  3L89 M;  2Y8T A;  3ZD2 A;  2G7I A;  2JRA A;  1HFI A;  2RLQ A;  3FGR A;  2CG7 A;  4K12 A;  1FBR A;  1QUB A;  5DN5 A;  3O8E B;  3OXU D;  1GKG A;  1TPN A;  3CI0 J;  2RKY A;  1GHQ B;  2XRB A;  2YRA A;  2LOJ A;  2XQW C;  1OJY A;  3GOV A;  2WII C;  1TPM A;  2XWB F;  5HYU B;  5JPM G;  1Z92 B;  4J38 B;  1GKN A;  1OK3 A;  4AYD A;  2BZM A;  3K3T A;  1RLH A;  3WSY A;  1NWV A;  2IZ3 A;  4CSY A;  4ONT D;  3FGT A;  1OJV A;  4LOT A;  1ELV A;  4YNX A;  4AYE A;  2JGW A;  4AYI A;  1TPG A;  2W81 A;  4AYM A;  1E5G A;  1H2Q P;  3F6K A;  3T5O A;  5DN4 A;  1G4F A;  2XWJ I;  1O9A A;  1Q3X A;  2JGX A;  2QY0 A;  3ZLD A;  3OP8 A;  2MCY A;  1MD8 A;  5FO8 C;  3ZLE A;  1CKL A;  1E8B A;  1HFH A;  1VVD A;  3EJH A;  4MSL A;  3NFP I;  5HZP B;  4PZ5 A;  2Y8S A;  1MD7 A;  5I0Q B;  3MQL A;  4C16 A;  1HCC A;  1GPZ A;  3TVJ A;  2YBY A;  1U5M A;  3KXV A;  2B5I D;  1OK1 A;  2CG6 A;  4FXG G;  2EHF A;  3R62 A;  3SW0 X;  1OK2 A;  3CAL A;  3WSX A; 
#chains in the Genus database with same CATH homology
 5HYP A;  1OK9 A;  3RJ3 D;  1E88 A;  2W80 A;  2V8E A;  1H04 P;  2CKU A;  1OJW A;  2UWN A;  3M7P A;  3KZJ A;  2A55 A;  4KKD A;  4MUC A;  1SRZ A;  3OED C;  1PPQ A;  3GXE A;  3ERB A;  3INB C;  2ERJ A;  1H03 P;  4WJG 2;  4B2R A;  2XRD A;  1SS2 A;  1QO6 A;  1VVC A;  2RKZ A;  3IX0 A;  5HYT B;  2RLP A;  4DJZ A;  3ZD1 A;  3IU3 I;  3ZRZ A;  4IGD A;  1UOT P;  4F4O C;  2O39 C;  4LOS A;  4JHS A;  1ZJK A;  2EC3 A;  4A5W B;  1LY2 A;  1G4G A;  4B2S A;  2KRI A;  1C1Z A;  2IZ4 A;  2RL0 A;  2MCZ A;  2KMS A;  4ZH1 D;  1H2P P;  1QGB A;  3L89 M;  3ZD2 A;  2G7I A;  2JRA A;  1HFI A;  2RLQ A;  2CG7 A;  4K12 A;  1FBR A;  1QUB A;  3O8E B;  3OXU D;  1GKG A;  1TPN A;  2RKY A;  1GHQ B;  2XRB A;  2YRA A;  2LOJ A;  2XQW C;  1OJY A;  3GOV A;  2WII C;  1TPM A;  2XWB F;  5HYU B;  5JPM G;  1Z92 B;  4J38 B;  1GKN A;  1OK3 A;  4AYD A;  2BZM A;  1NWV A;  2IZ3 A;  4CSY A;  4ONT D;  1OJV A;  4LOT A;  1ELV A;  4YNX A;  4AYE A;  2JGW A;  4AYI A;  1TPG A;  2W81 A;  4AYM A;  1E5G A;  1H2Q P;  3T5O A;  1G4F A;  2XWJ I;  1O9A A;  1Q3X A;  2JGX A;  2QY0 A;  3OP8 A;  2MCY A;  1MD8 A;  5FO8 C;  1CKL A;  1E8B A;  1HFH A;  1VVD A;  3EJH A;  3NFP I;  5HZP B;  4PZ5 A;  5I0Q B;  1MD7 A;  3MQL A;  4C16 A;  1HCC A;  1GPZ A;  3TVJ A;  2YBY A;  1U5M A;  3KXV A;  2B5I D;  1OK1 A;  2CG6 A;  4FXG G;  2EHF A;  3R62 A;  3SW0 X;  1OK2 A;  3CAL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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