2NYFA

Crystal structure of phenylalanine ammonia-lyase from nostoc punctiforme
Total Genus 192
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
sequence length
541
structure length
510
Chain Sequence
SIVTVGDRNLTIDEVVNVARHGTQVRLTDNADVIRGVQASCDYINNAVETAISREQAAELQTNLIWFLKSGAGNKLSLADVRAAMLLRANSHLYGASGIRLELIQRIETFLNAGVTPHVYEFGSIGDLVPLSYITGALIGLDPSFTVDFDGKEMDAVTALSRLGLPKLQLQPKEGLAMMNGTSVMTGIAANCVYDAKVLLALTMGVHALAIQGLYGTNQSFHPFIHQCKPHPGQLWTADQMFSLLKDSSLVREEQDRYSLRCLAQFIGPIVDGVSEITKQIEVEMNSVTDNPLIDVENQVSYHGGNFLGQYVGVTMDRLRYYIGLLAKHIDVQIALLVSPEFSNGLPPSLVGNSDRKVNMGLKGLQISGNSIMPLLSFYGNSLADRFPTHAEQFNQNINSQGYISANLTRRSVDIFQNYMAIALMFGVQAVDLRTYKMKGHYDARTCLSPNTVQLYTAVCEVVGKPLTSVRPYIWNDNEQCLDEHIARISADIAGGGLIVQAVEHIFSSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases: Kinetic and Structural Characterization.
pubmed doi rcsb
molecule tags Lyase
source organism Nostoc punctiforme
molecule keywords Nostoc punctiforme phenylalanine ammonia lyase
total genus 192
structure length 510
sequence length 541
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2006-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2nyfA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2nyfA02
3TV2A 4BABA 2X75A 4C5RA 2O6YA 5EYVA 5F92A 1HY0A 2QVEA 4C5SA 1J3UA 1GKJA 1TJVA 3OCFA 3UNVA 2OHYA 1TJ7A 3GZHA 1Q5NA 1VDKA 1GK2A 1EB4A 1YISA 4EFCA 1TJWA 3R6VA 2PTSA 1FUOA 4FFXA 4C6GA 3NZ4A 1GKMA 3RD8A 2E9FA 2O7EA 4EEIA 4APAA 3NO9A 2J91A 1GK3A 1DCNA 4NLEA 1DOFA 1YFEA 4ADMA 2NYFA 2O7FA 2PTQA 2RJRA 3E04A 1Y2MA 4V2RA 2FUSA 5D6BA 5EYTA 3QBPA 1K62A 1AUWA 1W27A 2YIIA 4NSLA 3RRPA 2NYNA 1U15A 5HW2A 1K7WA 3BHGA 2O78A 4FLCA 4HGVA 3KDZA 1C3UA 3R6YA 1JSWA 4BAAA 2PFMA 2QGAB 2O7BA 4CQ5A 1XWOA 5F91A 1FUQA 1YFMA 1FUPA 1I0AA 4APBA 1U16A 1C3CA 4V2QA 2RJSA 1TJUA 3GTDA 2PTRA 4ADLA 2HVGA 1KQ7A 3C8TA 3OCEA 2VD6A 1FURA 1T6PA 3R6QA 4MX2A 3KDYA 1B8FA 1HY1A 1RE5A 4C5UA 2O7DA 3CZOA 1T6JA
chains in the Genus database with same CATH superfamily
1XMCA 3TV2A 4BABA 2X75A 4WNLA 4C5RA 2O6YA 2VSFA 5EYVA 5F92A 1HY0A 1XL8A 2QVEA 4C5SA 1J3UA 1GKJA 1TJVA 3OCFA 3UNVA 2OHYA 1TJ7A 3GZHA 1Q5NA 1VDKA 1GK2A 1EB4A 1YISA 4EFCA 1TJWA 3R6VA 2PTSA 1FUOA 4FFXA 4C6GA 3NZ4A 1GKMA 5M0IA 2E9FA 3RD8A 5M0JA 3CRW1 2O7EA 4EEIA 4APAA 3NO9A 2J91A 1GK3A 1DCNA 4NLEA 1DOFA 1YFEA 4ADMA 2NYFA 1XLYA 2O7FA 2PTQA 2RJRA 3E04A 1Y2MA 4V2RA 2FUSA 5D6BA 5EYTA 3QBPA 1K62A 1AUWA 1W27A 2YIIA 4NSLA 1XMDA 2NYNA 2VL7A 3RRPA 1U15A 5HW2A 1K7WA 3BHGA 2O78A 4FLCA 4HGVA 5H8WA 3KDZA 1C3UA 3R6YA 1JSWA 4BAAA 2PFMA 2QGAB 2O7BA 4CQ5A 3CRVA 1XWOA 5F91A 1FUQA 1YFMA 1FUPA 1I0AA 4APBA 1U16A 1C3CA 4V2QA 2FENA 1XL7A 2RJSA 1TJUA 3GTDA 4A15A 2PTRA 4ADLA 2HVGA 1KQ7A 3C8TA 2FELA 3OCEA 2VD6A 1FURA 1T6PA 3R6QA 4MX2A 3KDYA 1B8FA 1HY1A 1RE5A 4C5UA 2O7DA 3CZOA 1T6JA
chains in the Genus database with same CATH topology
3TV2A 4BABA 2X75A 4C5RA 2O6YA 5EYVA 5F92A 1HY0A 2QVEA 4C5SA 1J3UA 1GKJA 1TJVA 3OCFA 3UNVA 2OHYA 1TJ7A 3GZHA 1Q5NA 1VDKA 1GK2A 1EB4A 1YISA 4EFCA 1TJWA 3R6VA 2PTSA 1FUOA 4FFXA 4C6GA 3NZ4A 1GKMA 3RD8A 2E9FA 2O7EA 4EEIA 4APAA 3NO9A 2J91A 1GK3A 1DCNA 4NLEA 1DOFA 1YFEA 4ADMA 2NYFA 2O7FA 2PTQA 2RJRA 3E04A 1Y2MA 4V2RA 2FUSA 5D6BA 5EYTA 3QBPA 1K62A 1AUWA 1W27A 2YIIA 4NSLA 3RRPA 2NYNA 1U15A 5HW2A 1K7WA 3BHGA 2O78A 4FLCA 4HGVA 3KDZA 1C3UA 3R6YA 1JSWA 4BAAA 2PFMA 2QGAB 2O7BA 4CQ5A 1XWOA 5F91A 1FUQA 1YFMA 1FUPA 1I0AA 4APBA 1U16A 1C3CA 4V2QA 2RJSA 1TJUA 3GTDA 2PTRA 4ADLA 2HVGA 1KQ7A 3C8TA 3OCEA 2VD6A 1FURA 1T6PA 3R6QA 4MX2A 3KDYA 1B8FA 1HY1A 1RE5A 4C5UA 2O7DA 3CZOA 1T6JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TV2 A;  4BAB A;  2X75 A;  4C5R A;  2O6Y A;  5EYV A;  5F92 A;  1HY0 A;  2QVE A;  4C5S A;  1J3U A;  1GKJ A;  1TJV A;  3OCF A;  3UNV A;  2OHY A;  1TJ7 A;  3GZH A;  1Q5N A;  1VDK A;  1GK2 A;  1EB4 A;  1YIS A;  4EFC A;  1TJW A;  3R6V A;  2PTS A;  1FUO A;  4FFX A;  4C6G A;  3NZ4 A;  1GKM A;  3RD8 A;  2E9F A;  2O7E A;  4EEI A;  4APA A;  3NO9 A;  2J91 A;  1GK3 A;  1DCN A;  4NLE A;  1DOF A;  1YFE A;  4ADM A;  2NYF A;  2O7F A;  2PTQ A;  2RJR A;  3E04 A;  1Y2M A;  4V2R A;  2FUS A;  5D6B A;  5EYT A;  3QBP A;  1K62 A;  1AUW A;  1W27 A;  2YII A;  4NSL A;  3RRP A;  2NYN A;  1U15 A;  5HW2 A;  1K7W A;  3BHG A;  2O78 A;  4FLC A;  4HGV A;  3KDZ A;  1C3U A;  3R6Y A;  1JSW A;  4BAA A;  2PFM A;  2QGA B;  2O7B A;  4CQ5 A;  1XWO A;  5F91 A;  1FUQ A;  1YFM A;  1FUP A;  1I0A A;  4APB A;  1U16 A;  1C3C A;  4V2Q A;  2RJS A;  1TJU A;  3GTD A;  2PTR A;  4ADL A;  2HVG A;  1KQ7 A;  3C8T A;  3OCE A;  2VD6 A;  1FUR A;  1T6P A;  3R6Q A;  4MX2 A;  3KDY A;  1B8F A;  1HY1 A;  1RE5 A;  4C5U A;  2O7D A;  3CZO A;  1T6J A; 
#chains in the Genus database with same CATH topology
 1XMC A;  3TV2 A;  4BAB A;  2X75 A;  4WNL A;  4C5R A;  2O6Y A;  2VSF A;  5EYV A;  5F92 A;  1HY0 A;  1XL8 A;  2QVE A;  4C5S A;  1J3U A;  1GKJ A;  1TJV A;  3OCF A;  3UNV A;  2OHY A;  1TJ7 A;  3GZH A;  1Q5N A;  1VDK A;  1GK2 A;  1EB4 A;  1YIS A;  4EFC A;  1TJW A;  3R6V A;  2PTS A;  1FUO A;  4FFX A;  4C6G A;  3NZ4 A;  1GKM A;  5M0I A;  2E9F A;  3RD8 A;  5M0J A;  3CRW 1;  2O7E A;  4EEI A;  4APA A;  3NO9 A;  2J91 A;  1GK3 A;  1DCN A;  4NLE A;  1DOF A;  1YFE A;  4ADM A;  2NYF A;  1XLY A;  2O7F A;  2PTQ A;  2RJR A;  3E04 A;  1Y2M A;  4V2R A;  2FUS A;  5D6B A;  5EYT A;  3QBP A;  1K62 A;  1AUW A;  1W27 A;  2YII A;  4NSL A;  1XMD A;  2NYN A;  2VL7 A;  3RRP A;  1U15 A;  5HW2 A;  1K7W A;  3BHG A;  2O78 A;  4FLC A;  4HGV A;  5H8W A;  3KDZ A;  1C3U A;  3R6Y A;  1JSW A;  4BAA A;  2PFM A;  2QGA B;  2O7B A;  4CQ5 A;  3CRV A;  1XWO A;  5F91 A;  1FUQ A;  1YFM A;  1FUP A;  1I0A A;  4APB A;  1U16 A;  1C3C A;  4V2Q A;  2FEN A;  1XL7 A;  2RJS A;  1TJU A;  3GTD A;  4A15 A;  2PTR A;  4ADL A;  2HVG A;  1KQ7 A;  3C8T A;  2FEL A;  3OCE A;  2VD6 A;  1FUR A;  1T6P A;  3R6Q A;  4MX2 A;  3KDY A;  1B8F A;  1HY1 A;  1RE5 A;  4C5U A;  2O7D A;  3CZO A;  1T6J A; 
#chains in the Genus database with same CATH homology
 3TV2 A;  4BAB A;  2X75 A;  4C5R A;  2O6Y A;  5EYV A;  5F92 A;  1HY0 A;  2QVE A;  4C5S A;  1J3U A;  1GKJ A;  1TJV A;  3OCF A;  3UNV A;  2OHY A;  1TJ7 A;  3GZH A;  1Q5N A;  1VDK A;  1GK2 A;  1EB4 A;  1YIS A;  4EFC A;  1TJW A;  3R6V A;  2PTS A;  1FUO A;  4FFX A;  4C6G A;  3NZ4 A;  1GKM A;  3RD8 A;  2E9F A;  2O7E A;  4EEI A;  4APA A;  3NO9 A;  2J91 A;  1GK3 A;  1DCN A;  4NLE A;  1DOF A;  1YFE A;  4ADM A;  2NYF A;  2O7F A;  2PTQ A;  2RJR A;  3E04 A;  1Y2M A;  4V2R A;  2FUS A;  5D6B A;  5EYT A;  3QBP A;  1K62 A;  1AUW A;  1W27 A;  2YII A;  4NSL A;  3RRP A;  2NYN A;  1U15 A;  5HW2 A;  1K7W A;  3BHG A;  2O78 A;  4FLC A;  4HGV A;  3KDZ A;  1C3U A;  3R6Y A;  1JSW A;  4BAA A;  2PFM A;  2QGA B;  2O7B A;  4CQ5 A;  1XWO A;  5F91 A;  1FUQ A;  1YFM A;  1FUP A;  1I0A A;  4APB A;  1U16 A;  1C3C A;  4V2Q A;  2RJS A;  1TJU A;  3GTD A;  2PTR A;  4ADL A;  2HVG A;  1KQ7 A;  3C8T A;  3OCE A;  2VD6 A;  1FUR A;  1T6P A;  3R6Q A;  4MX2 A;  3KDY A;  1B8F A;  1HY1 A;  1RE5 A;  4C5U A;  2O7D A;  3CZO A;  1T6J A; 
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