2O7D | Genus

Total Genus 193

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	193
sequence length	515
structure length	514
Chain Sequence	PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
source organism	Rhodobacter sphaeroides
publication title	Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. pubmed doi rcsb
molecule keywords	Putative histidine ammonia-lyase
total genus	193
structure length	514
sequence length	515
chains with identical sequence	B, C, D, E, F, G, H
ec nomenclature	ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date	2006-12-10

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00221	Lyase_aromatic	Aromatic amino acid lyase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.275.10	Mainly Alpha	Orthogonal Bundle	Fumarase C; Chain B, domain 1	Fumarase/aspartase (N-terminal domain)	2o7dA01
1.20.200.10	Mainly Alpha	Up-down Bundle	Fumarase C; Chain A, domain 2	Fumarase/aspartase (Central domain)	2o7dA02

2O7BA 5EYTA 2O7EA 1YISA 1FURA 1GKJA 3OCFA 3UNVA 2PTQA 3BHGA 1YFEA 4EFCA 1YFMA 2OHYA 2O6YA 1GK3A 2NYNA 1TJUA 2PTSA 4MX2A 1FUQA 1TJWA 1J3UA 2FUSA 3RRPA 1TJVA 1HY0A 1RE5A 2RJRA 4NSLA 2NYFA 4ADLA 2O7FA 1W27A 1DCNA 1DOFA 1T6JA 2VD6A 4C5UA 2QGAB 3GTDA 5D6BA 1Q5NA 4BABA 2HVGA 3OCEA 3QBPA 4CQ5A 1K7WA 2E9FA 5HW2A 4BAAA 5F91A 1C3CA 4V2QA 3GZHA 5F92A 2O78A 1FUOA 1AUWA 3E04A 4ADMA 3R6QA 1K62A 3RD8A 3NZ4A 4FLCA 3R6VA 4FFXA 4C5SA 2PFMA 4APAA 3NO9A 3R6YA 4C5RA 3KDYA 1TJ7A 4HGVA 4V2RA 2RJSA 4C6GA 3TV2A 2QVEA 1VDKA 1Y2MA 4NLEA 1KQ7A 1U16A 3KDZA 1B8FA 1HY1A 2PTRA 2J91A 4APBA 5EYVA 1U15A 1GKMA 2X75A 4EEIA 2O7DA 1GK2A 3CZOA 3C8TA 2YIIA 1I0AA 1EB4A 1FUPA 1T6PA 1C3UA 1JSWA 1XWOA
chains in the Genus database with same CATH superfamily

2O7BA 5EYTA 2O7EA 1YISA 1FURA 1GKJA 3OCFA 3CRW1 3UNVA 4WNLA 2PTQA 3BHGA 1YFEA 4EFCA 5H8WA 1YFMA 2OHYA 1XL7A 2O6YA 1GK3A 3CRVA 2NYNA 1XL8A 1TJUA 2PTSA 4MX2A 1FUQA 1TJWA 1J3UA 2FUSA 3RRPA 1TJVA 1HY0A 1RE5A 2RJRA 2VL7A 4NSLA 2NYFA 4ADLA 2O7FA 1W27A 1DCNA 1DOFA 1T6JA 2VD6A 4C5UA 2QGAB 3GTDA 5D6BA 1Q5NA 4BABA 2HVGA 3OCEA 3QBPA 4CQ5A 1K7WA 2E9FA 5HW2A 4BAAA 5M0JA 5F91A 1C3CA 4V2QA 3GZHA 5F92A 2O78A 1FUOA 1AUWA 5M0IA 3E04A 4ADMA 3R6QA 1K62A 3RD8A 3NZ4A 4FLCA 3R6VA 4FFXA 4C5SA 2PFMA 4APAA 3NO9A 3R6YA 4C5RA 3KDYA 1TJ7A 4HGVA 4V2RA 2RJSA 4C6GA 3TV2A 1XMCA 2QVEA 1XLYA 1VDKA 1Y2MA 4NLEA 2VSFA 4A15A 1KQ7A 1U16A 3KDZA 1B8FA 1HY1A 2PTRA 2J91A 4APBA 5EYVA 1U15A 1GKMA 2X75A 4EEIA 2O7DA 2FENA 1GK2A 3CZOA 3C8TA 2FELA 2YIIA 1I0AA 1EB4A 1XMDA 1FUPA 1T6PA 1C3UA 1JSWA 1XWOA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2O7B A;  5EYT A;  2O7E A;  1YIS A;  1FUR A;  1GKJ A;  3OCF A;  3UNV A;  2PTQ A;  3BHG A;  1YFE A;  4EFC A;  1YFM A;  2OHY A;  2O6Y A;  1GK3 A;  2NYN A;  1TJU A;  2PTS A;  4MX2 A;  1FUQ A;  1TJW A;  1J3U A;  2FUS A;  3RRP A;  1TJV A;  1HY0 A;  1RE5 A;  2RJR A;  4NSL A;  2NYF A;  4ADL A;  2O7F A;  1W27 A;  1DCN A;  1DOF A;  1T6J A;  2VD6 A;  4C5U A;  2QGA B;  3GTD A;  5D6B A;  1Q5N A;  4BAB A;  2HVG A;  3OCE A;  3QBP A;  4CQ5 A;  1K7W A;  2E9F A;  5HW2 A;  4BAA A;  5F91 A;  1C3C A;  4V2Q A;  3GZH A;  5F92 A;  2O78 A;  1FUO A;  1AUW A;  3E04 A;  4ADM A;  3R6Q A;  1K62 A;  3RD8 A;  3NZ4 A;  4FLC A;  3R6V A;  4FFX A;  4C5S A;  2PFM A;  4APA A;  3NO9 A;  3R6Y A;  4C5R A;  3KDY A;  1TJ7 A;  4HGV A;  4V2R A;  2RJS A;  4C6G A;  3TV2 A;  2QVE A;  1VDK A;  1Y2M A;  4NLE A;  1KQ7 A;  1U16 A;  3KDZ A;  1B8F A;  1HY1 A;  2PTR A;  2J91 A;  4APB A;  5EYV A;  1U15 A;  1GKM A;  2X75 A;  4EEI A;  2O7D A;  1GK2 A;  3CZO A;  3C8T A;  2YII A;  1I0A A;  1EB4 A;  1FUP A;  1T6P A;  1C3U A;  1JSW A;  1XWO A; 
#chains in the Genus database with same CATH topology
 2O7B A;  5EYT A;  2O7E A;  1YIS A;  1FUR A;  1GKJ A;  3OCF A;  3CRW 1;  3UNV A;  4WNL A;  2PTQ A;  3BHG A;  1YFE A;  4EFC A;  5H8W A;  1YFM A;  2OHY A;  1XL7 A;  2O6Y A;  1GK3 A;  3CRV A;  2NYN A;  1XL8 A;  1TJU A;  2PTS A;  4MX2 A;  1FUQ A;  1TJW A;  1J3U A;  2FUS A;  3RRP A;  1TJV A;  1HY0 A;  1RE5 A;  2RJR A;  2VL7 A;  4NSL A;  2NYF A;  4ADL A;  2O7F A;  1W27 A;  1DCN A;  1DOF A;  1T6J A;  2VD6 A;  4C5U A;  2QGA B;  3GTD A;  5D6B A;  1Q5N A;  4BAB A;  2HVG A;  3OCE A;  3QBP A;  4CQ5 A;  1K7W A;  2E9F A;  5HW2 A;  4BAA A;  5M0J A;  5F91 A;  1C3C A;  4V2Q A;  3GZH A;  5F92 A;  2O78 A;  1FUO A;  1AUW A;  5M0I A;  3E04 A;  4ADM A;  3R6Q A;  1K62 A;  3RD8 A;  3NZ4 A;  4FLC A;  3R6V A;  4FFX A;  4C5S A;  2PFM A;  4APA A;  3NO9 A;  3R6Y A;  4C5R A;  3KDY A;  1TJ7 A;  4HGV A;  4V2R A;  2RJS A;  4C6G A;  3TV2 A;  1XMC A;  2QVE A;  1XLY A;  1VDK A;  1Y2M A;  4NLE A;  2VSF A;  4A15 A;  1KQ7 A;  1U16 A;  3KDZ A;  1B8F A;  1HY1 A;  2PTR A;  2J91 A;  4APB A;  5EYV A;  1U15 A;  1GKM A;  2X75 A;  4EEI A;  2O7D A;  2FEN A;  1GK2 A;  3CZO A;  3C8T A;  2FEL A;  2YII A;  1I0A A;  1EB4 A;  1XMD A;  1FUP A;  1T6P A;  1C3U A;  1JSW A;  1XWO A; 
#chains in the Genus database with same CATH homology
 2O7B A;  5EYT A;  2O7E A;  1YIS A;  1FUR A;  1GKJ A;  3OCF A;  3UNV A;  2PTQ A;  3BHG A;  1YFE A;  4EFC A;  1YFM A;  2OHY A;  2O6Y A;  1GK3 A;  2NYN A;  1TJU A;  2PTS A;  4MX2 A;  1FUQ A;  1TJW A;  1J3U A;  2FUS A;  3RRP A;  1TJV A;  1HY0 A;  1RE5 A;  2RJR A;  4NSL A;  2NYF A;  4ADL A;  2O7F A;  1W27 A;  1DCN A;  1DOF A;  1T6J A;  2VD6 A;  4C5U A;  2QGA B;  3GTD A;  5D6B A;  1Q5N A;  4BAB A;  2HVG A;  3OCE A;  3QBP A;  4CQ5 A;  1K7W A;  2E9F A;  5HW2 A;  4BAA A;  5F91 A;  1C3C A;  4V2Q A;  3GZH A;  5F92 A;  2O78 A;  1FUO A;  1AUW A;  3E04 A;  4ADM A;  3R6Q A;  1K62 A;  3RD8 A;  3NZ4 A;  4FLC A;  3R6V A;  4FFX A;  4C5S A;  2PFM A;  4APA A;  3NO9 A;  3R6Y A;  4C5R A;  3KDY A;  1TJ7 A;  4HGV A;  4V2R A;  2RJS A;  4C6G A;  3TV2 A;  2QVE A;  1VDK A;  1Y2M A;  4NLE A;  1KQ7 A;  1U16 A;  3KDZ A;  1B8F A;  1HY1 A;  2PTR A;  2J91 A;  4APB A;  5EYV A;  1U15 A;  1GKM A;  2X75 A;  4EEI A;  2O7D A;  1GK2 A;  3CZO A;  3C8T A;  2YII A;  1I0A A;  1EB4 A;  1FUP A;  1T6P A;  1C3U A;  1JSW A;  1XWO A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2O7DA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations