2RJS | Genus

Total Genus 198

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	198
sequence length	526
structure length	525
Chain Sequence	PVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Isomerase
source organism	Streptomyces globisporus
publication title	Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM. pubmed doi rcsb
molecule keywords	Tyrosine aminomutase
total genus	198
structure length	525
sequence length	526
chains with identical sequence	B
ec nomenclature	ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date	2007-10-15

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00221	Lyase_aromatic	Aromatic amino acid lyase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.275.10	Mainly Alpha	Orthogonal Bundle	Fumarase C; Chain B, domain 1	Fumarase/aspartase (N-terminal domain)	2rjsA01
1.20.200.10	Mainly Alpha	Up-down Bundle	Fumarase C; Chain A, domain 2	Fumarase/aspartase (Central domain)	2rjsA02

3GZHA 5EYTA 4V2RA 4V2QA 2O7EA 1C3UA 1YFMA 4APAA 3RD8A 5HW2A 3CZOA 1VDKA 1YISA 2RJSA 1GK2A 1T6JA 3C8TA 2PTSA 4MX2A 1KQ7A 5D6BA 1T6PA 3BHGA 1J3UA 4NLEA 4EFCA 3UNVA 1YFEA 1DCNA 1K7WA 1Q5NA 1FUOA 3KDZA 2HVGA 3GTDA 2YIIA 4APBA 2QGAB 4C5RA 1C3CA 3NO9A 1TJVA 5F92A 4BABA 1Y2MA 2QVEA 4FLCA 1TJUA 2OHYA 4ADLA 1FUPA 4C5UA 1U16A 2O6YA 1W27A 2RJRA 1RE5A 2NYFA 3R6YA 2PFMA 3E04A 2O7DA 3RRPA 5F91A 1GKMA 3KDYA 3QBPA 1EB4A 3OCEA 1TJ7A 1AUWA 4HGVA 1FUQA 2J91A 1HY0A 4NSLA 4BAAA 3OCFA 3R6QA 1TJWA 2X75A 1JSWA 1DOFA 1XWOA 2PTQA 1K62A 2NYNA 1FURA 4C6GA 1GK3A 1U15A 2PTRA 3R6VA 1HY1A 1B8FA 2E9FA 4ADMA 3TV2A 2O78A 4CQ5A 4FFXA 1I0AA 5EYVA 2O7FA 1GKJA 2O7BA 4C5SA 2FUSA 4EEIA 3NZ4A 2VD6A
chains in the Genus database with same CATH superfamily

3GZHA 5EYTA 4V2RA 5H8WA 4V2QA 2O7EA 1C3UA 1YFMA 4APAA 3RD8A 5HW2A 3CZOA 1VDKA 1YISA 2RJSA 1XMDA 1GK2A 1T6JA 3C8TA 5M0JA 2FELA 4WNLA 2PTSA 4A15A 4MX2A 1KQ7A 5D6BA 1T6PA 3BHGA 1J3UA 4NLEA 4EFCA 3UNVA 1YFEA 1DCNA 1K7WA 1Q5NA 1FUOA 3KDZA 2HVGA 3GTDA 2YIIA 4APBA 2QGAB 4C5RA 1C3CA 3NO9A 1TJVA 2VSFA 1XLYA 5M0IA 5F92A 4BABA 1Y2MA 2QVEA 4FLCA 1TJUA 1XL8A 2OHYA 4ADLA 1FUPA 4C5UA 1U16A 2O6YA 1W27A 2RJRA 1RE5A 2NYFA 3R6YA 2FENA 1XL7A 2PFMA 3E04A 2O7DA 3RRPA 5F91A 1GKMA 3KDYA 3QBPA 3CRW1 1EB4A 3OCEA 1TJ7A 1AUWA 4HGVA 1FUQA 2J91A 1HY0A 4NSLA 4BAAA 3OCFA 3R6QA 1TJWA 2X75A 3CRVA 1JSWA 1DOFA 1XWOA 2PTQA 1K62A 2NYNA 1FURA 4C6GA 1GK3A 1U15A 2PTRA 3R6VA 1HY1A 1B8FA 2E9FA 4ADMA 3TV2A 2O78A 1XMCA 4CQ5A 4FFXA 1I0AA 5EYVA 2O7FA 2VL7A 1GKJA 2O7BA 4C5SA 2FUSA 4EEIA 3NZ4A 2VD6A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3GZH A;  5EYT A;  4V2R A;  4V2Q A;  2O7E A;  1C3U A;  1YFM A;  4APA A;  3RD8 A;  5HW2 A;  3CZO A;  1VDK A;  1YIS A;  2RJS A;  1GK2 A;  1T6J A;  3C8T A;  2PTS A;  4MX2 A;  1KQ7 A;  5D6B A;  1T6P A;  3BHG A;  1J3U A;  4NLE A;  4EFC A;  3UNV A;  1YFE A;  1DCN A;  1K7W A;  1Q5N A;  1FUO A;  3KDZ A;  2HVG A;  3GTD A;  2YII A;  4APB A;  2QGA B;  4C5R A;  1C3C A;  3NO9 A;  1TJV A;  5F92 A;  4BAB A;  1Y2M A;  2QVE A;  4FLC A;  1TJU A;  2OHY A;  4ADL A;  1FUP A;  4C5U A;  1U16 A;  2O6Y A;  1W27 A;  2RJR A;  1RE5 A;  2NYF A;  3R6Y A;  2PFM A;  3E04 A;  2O7D A;  3RRP A;  5F91 A;  1GKM A;  3KDY A;  3QBP A;  1EB4 A;  3OCE A;  1TJ7 A;  1AUW A;  4HGV A;  1FUQ A;  2J91 A;  1HY0 A;  4NSL A;  4BAA A;  3OCF A;  3R6Q A;  1TJW A;  2X75 A;  1JSW A;  1DOF A;  1XWO A;  2PTQ A;  1K62 A;  2NYN A;  1FUR A;  4C6G A;  1GK3 A;  1U15 A;  2PTR A;  3R6V A;  1HY1 A;  1B8F A;  2E9F A;  4ADM A;  3TV2 A;  2O78 A;  4CQ5 A;  4FFX A;  1I0A A;  5EYV A;  2O7F A;  1GKJ A;  2O7B A;  4C5S A;  2FUS A;  4EEI A;  3NZ4 A;  2VD6 A; 
#chains in the Genus database with same CATH topology
 3GZH A;  5EYT A;  4V2R A;  5H8W A;  4V2Q A;  2O7E A;  1C3U A;  1YFM A;  4APA A;  3RD8 A;  5HW2 A;  3CZO A;  1VDK A;  1YIS A;  2RJS A;  1XMD A;  1GK2 A;  1T6J A;  3C8T A;  5M0J A;  2FEL A;  4WNL A;  2PTS A;  4A15 A;  4MX2 A;  1KQ7 A;  5D6B A;  1T6P A;  3BHG A;  1J3U A;  4NLE A;  4EFC A;  3UNV A;  1YFE A;  1DCN A;  1K7W A;  1Q5N A;  1FUO A;  3KDZ A;  2HVG A;  3GTD A;  2YII A;  4APB A;  2QGA B;  4C5R A;  1C3C A;  3NO9 A;  1TJV A;  2VSF A;  1XLY A;  5M0I A;  5F92 A;  4BAB A;  1Y2M A;  2QVE A;  4FLC A;  1TJU A;  1XL8 A;  2OHY A;  4ADL A;  1FUP A;  4C5U A;  1U16 A;  2O6Y A;  1W27 A;  2RJR A;  1RE5 A;  2NYF A;  3R6Y A;  2FEN A;  1XL7 A;  2PFM A;  3E04 A;  2O7D A;  3RRP A;  5F91 A;  1GKM A;  3KDY A;  3QBP A;  3CRW 1;  1EB4 A;  3OCE A;  1TJ7 A;  1AUW A;  4HGV A;  1FUQ A;  2J91 A;  1HY0 A;  4NSL A;  4BAA A;  3OCF A;  3R6Q A;  1TJW A;  2X75 A;  3CRV A;  1JSW A;  1DOF A;  1XWO A;  2PTQ A;  1K62 A;  2NYN A;  1FUR A;  4C6G A;  1GK3 A;  1U15 A;  2PTR A;  3R6V A;  1HY1 A;  1B8F A;  2E9F A;  4ADM A;  3TV2 A;  2O78 A;  1XMC A;  4CQ5 A;  4FFX A;  1I0A A;  5EYV A;  2O7F A;  2VL7 A;  1GKJ A;  2O7B A;  4C5S A;  2FUS A;  4EEI A;  3NZ4 A;  2VD6 A; 
#chains in the Genus database with same CATH homology
 3GZH A;  5EYT A;  4V2R A;  4V2Q A;  2O7E A;  1C3U A;  1YFM A;  4APA A;  3RD8 A;  5HW2 A;  3CZO A;  1VDK A;  1YIS A;  2RJS A;  1GK2 A;  1T6J A;  3C8T A;  2PTS A;  4MX2 A;  1KQ7 A;  5D6B A;  1T6P A;  3BHG A;  1J3U A;  4NLE A;  4EFC A;  3UNV A;  1YFE A;  1DCN A;  1K7W A;  1Q5N A;  1FUO A;  3KDZ A;  2HVG A;  3GTD A;  2YII A;  4APB A;  2QGA B;  4C5R A;  1C3C A;  3NO9 A;  1TJV A;  5F92 A;  4BAB A;  1Y2M A;  2QVE A;  4FLC A;  1TJU A;  2OHY A;  4ADL A;  1FUP A;  4C5U A;  1U16 A;  2O6Y A;  1W27 A;  2RJR A;  1RE5 A;  2NYF A;  3R6Y A;  2PFM A;  3E04 A;  2O7D A;  3RRP A;  5F91 A;  1GKM A;  3KDY A;  3QBP A;  1EB4 A;  3OCE A;  1TJ7 A;  1AUW A;  4HGV A;  1FUQ A;  2J91 A;  1HY0 A;  4NSL A;  4BAA A;  3OCF A;  3R6Q A;  1TJW A;  2X75 A;  1JSW A;  1DOF A;  1XWO A;  2PTQ A;  1K62 A;  2NYN A;  1FUR A;  4C6G A;  1GK3 A;  1U15 A;  2PTR A;  3R6V A;  1HY1 A;  1B8F A;  2E9F A;  4ADM A;  3TV2 A;  2O78 A;  4CQ5 A;  4FFX A;  1I0A A;  5EYV A;  2O7F A;  1GKJ A;  2O7B A;  4C5S A;  2FUS A;  4EEI A;  3NZ4 A;  2VD6 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2RJSA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations