2RLQA

Nmr structure of ccp modules 2-3 of complement factor h
Total Genus 22
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
123
structure length
123
Chain Sequence
PCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDGWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Complement factor H
total genus 22
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2007-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2rlqA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2rlqA02
1GKGA 2W81A 2XRDA 5HYTB 1H04P 3ZD2A 3INBC 1Q3XA 1MD7A 4B2RA 1MD8A 3GOVA 3OP8A 3RJ3D 2BZMA 2JGWA 1GKNA 3O8EB 1TPNA 4PZ5A 1OK2A 3ZRZA 1VVDA 3IU3I 2O39C 3IX0A 3R62A 1H03P 5HZPB 2IZ4A 2EC3A 2G7IA 1LY2A 1QO6A 2W80A 3OEDC 1VVCA 3M7PA 2V8EA 4LOSA 1Z92B 2YRAA 1E5GA 2XWBF 1GPZA 2B5ID 3GXEA 2RKZA 1HFHA 3ERBA 2KRIA 1OJWA 4B2SA 1OK3A 4IGDA 2CG6A 3KXVA 1G4FA 1G4GA 2XQWC 1CKLA 1TPMA 1SRZA 5I0QB 2XRBA 1HFIA 4ONTD 1U5MA 5FO8C 1H2PP 1QUBA 4K12A 1ZJKA 4C16A 2JGXA 3L89M 1O9AA 1PPQA 2CG7A 5JPMG 4CSYA 2RLPA 4AYIA 1E88A 1GHQB 3TVJA 3MQLA 5HYUB 5HYPA 2MCYA 1NWVA 2RKYA 2A55A 2RLQA 2ERJA 3ZD1A 1OJYA 3T5OA 4LOTA 1H2QP 3SW0X 1OK1A 4AYDA 2WIIC 3KZJA 1UOTP 2JRAA 3NFPI 1TPGA 4A5WB 1HCCA 3EJHA 4JHSA 2XWJI 2UWNA 1FBRA 2LOJA 1QGBA 1OK9A 1E8BA 4FXGG 2IZ3A 2EHFA 1SS2A 4ZH1D 2MCZA 4AYEA 4F4OC 1ELVA 2RL0A 4J38B 4WJG2 4YNXA 1C1ZA 2CKUA 4DJZA 2YBYA 2KMSA 3CALA 4AYMA 4KKDA 2QY0A 3OXUD 1OJVA 4MUCA
chains in the Genus database with same CATH superfamily
3WSYA 1GKGA 3F6KA 2W81A 2XRDA 5HYTB 1H04P 3ZD2A 3INBC 1Q3XA 1MD7A 4B2RA 1MD8A 3GOVA 3OP8A 3RJ3D 2BZMA 2JGWA 1GKNA 3O8EB 1TPNA 4PZ5A 1OK2A 3ZRZA 1VVDA 3IU3I 2O39C 3IX0A 2Y8SA 3R62A 1H03P 5HZPB 2IZ4A 2EC3A 2G7IA 1LY2A 1QO6A 2W80A 3OEDC 3WSXA 4YIZA 1VVCA 3M7PA 2V8EA 2Y8TA 4LOSA 1Z92B 4PO7A 2YRAA 1E5GA 2XWBF 1GPZA 2I2LA 3FGTA 2B5ID 3ZLDA 3FGRA 3GXEA 2RKZA 1HFHA 3ERBA 2KRIA 1OJWA 4B2SA 1OK3A 4IGDA 2CG6A 3K3TA 3KXVA 1G4FA 1G4GA 2XQWC 1CKLA 1TPMA 4MSLA 1SRZA 5I0QB 2XRBA 3VWOA 3ZLEA 1HFIA 4ONTD 1U5MA 5FO8C 1H2PP 1RLHA 1QUBA 4K12A 1ZJKA 4C16A 2JGXA 3L89M 1O9AA 1PPQA 2CG7A 5JPMG 4CSYA 2RLPA 4AYIA 1E88A 1GHQB 3TVJA 3MQLA 5HYUB 5HYPA 2MCYA 1NWVA 2RKYA 2A55A 2RLQA 2ERJA 4BWCA 3ZD1A 1OJYA 3T5OA 2X2ZA 4LOTA 1H2QP 2ZYCA 3SW0X 1OK1A 4AYDA 2WIIC 3KZJA 1UOTP 2JRAA 3NFPI 1TPGA 4A5WB 5DN4A 1HCCA 3EJHA 4JHSA 5DN5A 2XWJI 3NJAA 2UWNA 1FBRA 2LOJA 4N7EA 1QGBA 1OK9A 1E8BA 4FXGG 2IZ3A 4APLA 2EHFA 1SS2A 4ZH1D 2MCZA 4AYEA 4F4OC 1ELVA 2RL0A 4J38B 4WJG2 4YNXA 1C1ZA 2CKUA 4DJZA 2Y8RA 2YBYA 2KMSA 3CI0J 3CALA 4AYMA 4KKDA 2QY0A 3OXUD 1OJVA 4MUCA
chains in the Genus database with same CATH topology
1GKGA 2W81A 2XRDA 5HYTB 1H04P 3ZD2A 3INBC 1Q3XA 1MD7A 4B2RA 1MD8A 3GOVA 3OP8A 3RJ3D 2BZMA 2JGWA 1GKNA 3O8EB 1TPNA 4PZ5A 1OK2A 3ZRZA 1VVDA 3IU3I 2O39C 3IX0A 3R62A 1H03P 5HZPB 2IZ4A 2EC3A 2G7IA 1LY2A 1QO6A 2W80A 3OEDC 1VVCA 3M7PA 2V8EA 4LOSA 1Z92B 2YRAA 1E5GA 2XWBF 1GPZA 2B5ID 3GXEA 2RKZA 1HFHA 3ERBA 2KRIA 1OJWA 4B2SA 1OK3A 4IGDA 2CG6A 3KXVA 1G4FA 1G4GA 2XQWC 1CKLA 1TPMA 1SRZA 5I0QB 2XRBA 1HFIA 4ONTD 1U5MA 5FO8C 1H2PP 1QUBA 4K12A 1ZJKA 4C16A 2JGXA 3L89M 1O9AA 1PPQA 2CG7A 5JPMG 4CSYA 2RLPA 4AYIA 1E88A 1GHQB 3TVJA 3MQLA 5HYUB 5HYPA 2MCYA 1NWVA 2RKYA 2A55A 2RLQA 2ERJA 3ZD1A 1OJYA 3T5OA 4LOTA 1H2QP 3SW0X 1OK1A 4AYDA 2WIIC 3KZJA 1UOTP 2JRAA 3NFPI 1TPGA 4A5WB 1HCCA 3EJHA 4JHSA 2XWJI 2UWNA 1FBRA 2LOJA 1QGBA 1OK9A 1E8BA 4FXGG 2IZ3A 2EHFA 1SS2A 4ZH1D 2MCZA 4AYEA 4F4OC 1ELVA 2RL0A 4J38B 4WJG2 4YNXA 1C1ZA 2CKUA 4DJZA 2YBYA 2KMSA 3CALA 4AYMA 4KKDA 2QY0A 3OXUD 1OJVA 4MUCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GKG A;  2W81 A;  2XRD A;  5HYT B;  1H04 P;  3ZD2 A;  3INB C;  1Q3X A;  1MD7 A;  4B2R A;  1MD8 A;  3GOV A;  3OP8 A;  3RJ3 D;  2BZM A;  2JGW A;  1GKN A;  3O8E B;  1TPN A;  4PZ5 A;  1OK2 A;  3ZRZ A;  1VVD A;  3IU3 I;  2O39 C;  3IX0 A;  3R62 A;  1H03 P;  5HZP B;  2IZ4 A;  2EC3 A;  2G7I A;  1LY2 A;  1QO6 A;  2W80 A;  3OED C;  1VVC A;  3M7P A;  2V8E A;  4LOS A;  1Z92 B;  2YRA A;  1E5G A;  2XWB F;  1GPZ A;  2B5I D;  3GXE A;  2RKZ A;  1HFH A;  3ERB A;  2KRI A;  1OJW A;  4B2S A;  1OK3 A;  4IGD A;  2CG6 A;  3KXV A;  1G4F A;  1G4G A;  2XQW C;  1CKL A;  1TPM A;  1SRZ A;  5I0Q B;  2XRB A;  1HFI A;  4ONT D;  1U5M A;  5FO8 C;  1H2P P;  1QUB A;  4K12 A;  1ZJK A;  4C16 A;  2JGX A;  3L89 M;  1O9A A;  1PPQ A;  2CG7 A;  5JPM G;  4CSY A;  2RLP A;  4AYI A;  1E88 A;  1GHQ B;  3TVJ A;  3MQL A;  5HYU B;  5HYP A;  2MCY A;  1NWV A;  2RKY A;  2A55 A;  2RLQ A;  2ERJ A;  3ZD1 A;  1OJY A;  3T5O A;  4LOT A;  1H2Q P;  3SW0 X;  1OK1 A;  4AYD A;  2WII C;  3KZJ A;  1UOT P;  2JRA A;  3NFP I;  1TPG A;  4A5W B;  1HCC A;  3EJH A;  4JHS A;  2XWJ I;  2UWN A;  1FBR A;  2LOJ A;  1QGB A;  1OK9 A;  1E8B A;  4FXG G;  2IZ3 A;  2EHF A;  1SS2 A;  4ZH1 D;  2MCZ A;  4AYE A;  4F4O C;  1ELV A;  2RL0 A;  4J38 B;  4WJG 2;  4YNX A;  1C1Z A;  2CKU A;  4DJZ A;  2YBY A;  2KMS A;  3CAL A;  4AYM A;  4KKD A;  2QY0 A;  3OXU D;  1OJV A;  4MUC A; 
#chains in the Genus database with same CATH topology
 3WSY A;  1GKG A;  3F6K A;  2W81 A;  2XRD A;  5HYT B;  1H04 P;  3ZD2 A;  3INB C;  1Q3X A;  1MD7 A;  4B2R A;  1MD8 A;  3GOV A;  3OP8 A;  3RJ3 D;  2BZM A;  2JGW A;  1GKN A;  3O8E B;  1TPN A;  4PZ5 A;  1OK2 A;  3ZRZ A;  1VVD A;  3IU3 I;  2O39 C;  3IX0 A;  2Y8S A;  3R62 A;  1H03 P;  5HZP B;  2IZ4 A;  2EC3 A;  2G7I A;  1LY2 A;  1QO6 A;  2W80 A;  3OED C;  3WSX A;  4YIZ A;  1VVC A;  3M7P A;  2V8E A;  2Y8T A;  4LOS A;  1Z92 B;  4PO7 A;  2YRA A;  1E5G A;  2XWB F;  1GPZ A;  2I2L A;  3FGT A;  2B5I D;  3ZLD A;  3FGR A;  3GXE A;  2RKZ A;  1HFH A;  3ERB A;  2KRI A;  1OJW A;  4B2S A;  1OK3 A;  4IGD A;  2CG6 A;  3K3T A;  3KXV A;  1G4F A;  1G4G A;  2XQW C;  1CKL A;  1TPM A;  4MSL A;  1SRZ A;  5I0Q B;  2XRB A;  3VWO A;  3ZLE A;  1HFI A;  4ONT D;  1U5M A;  5FO8 C;  1H2P P;  1RLH A;  1QUB A;  4K12 A;  1ZJK A;  4C16 A;  2JGX A;  3L89 M;  1O9A A;  1PPQ A;  2CG7 A;  5JPM G;  4CSY A;  2RLP A;  4AYI A;  1E88 A;  1GHQ B;  3TVJ A;  3MQL A;  5HYU B;  5HYP A;  2MCY A;  1NWV A;  2RKY A;  2A55 A;  2RLQ A;  2ERJ A;  4BWC A;  3ZD1 A;  1OJY A;  3T5O A;  2X2Z A;  4LOT A;  1H2Q P;  2ZYC A;  3SW0 X;  1OK1 A;  4AYD A;  2WII C;  3KZJ A;  1UOT P;  2JRA A;  3NFP I;  1TPG A;  4A5W B;  5DN4 A;  1HCC A;  3EJH A;  4JHS A;  5DN5 A;  2XWJ I;  3NJA A;  2UWN A;  1FBR A;  2LOJ A;  4N7E A;  1QGB A;  1OK9 A;  1E8B A;  4FXG G;  2IZ3 A;  4APL A;  2EHF A;  1SS2 A;  4ZH1 D;  2MCZ A;  4AYE A;  4F4O C;  1ELV A;  2RL0 A;  4J38 B;  4WJG 2;  4YNX A;  1C1Z A;  2CKU A;  4DJZ A;  2Y8R A;  2YBY A;  2KMS A;  3CI0 J;  3CAL A;  4AYM A;  4KKD A;  2QY0 A;  3OXU D;  1OJV A;  4MUC A; 
#chains in the Genus database with same CATH homology
 1GKG A;  2W81 A;  2XRD A;  5HYT B;  1H04 P;  3ZD2 A;  3INB C;  1Q3X A;  1MD7 A;  4B2R A;  1MD8 A;  3GOV A;  3OP8 A;  3RJ3 D;  2BZM A;  2JGW A;  1GKN A;  3O8E B;  1TPN A;  4PZ5 A;  1OK2 A;  3ZRZ A;  1VVD A;  3IU3 I;  2O39 C;  3IX0 A;  3R62 A;  1H03 P;  5HZP B;  2IZ4 A;  2EC3 A;  2G7I A;  1LY2 A;  1QO6 A;  2W80 A;  3OED C;  1VVC A;  3M7P A;  2V8E A;  4LOS A;  1Z92 B;  2YRA A;  1E5G A;  2XWB F;  1GPZ A;  2B5I D;  3GXE A;  2RKZ A;  1HFH A;  3ERB A;  2KRI A;  1OJW A;  4B2S A;  1OK3 A;  4IGD A;  2CG6 A;  3KXV A;  1G4F A;  1G4G A;  2XQW C;  1CKL A;  1TPM A;  1SRZ A;  5I0Q B;  2XRB A;  1HFI A;  4ONT D;  1U5M A;  5FO8 C;  1H2P P;  1QUB A;  4K12 A;  1ZJK A;  4C16 A;  2JGX A;  3L89 M;  1O9A A;  1PPQ A;  2CG7 A;  5JPM G;  4CSY A;  2RLP A;  4AYI A;  1E88 A;  1GHQ B;  3TVJ A;  3MQL A;  5HYU B;  5HYP A;  2MCY A;  1NWV A;  2RKY A;  2A55 A;  2RLQ A;  2ERJ A;  3ZD1 A;  1OJY A;  3T5O A;  4LOT A;  1H2Q P;  3SW0 X;  1OK1 A;  4AYD A;  2WII C;  3KZJ A;  1UOT P;  2JRA A;  3NFP I;  1TPG A;  4A5W B;  1HCC A;  3EJH A;  4JHS A;  2XWJ I;  2UWN A;  1FBR A;  2LOJ A;  1QGB A;  1OK9 A;  1E8B A;  4FXG G;  2IZ3 A;  2EHF A;  1SS2 A;  4ZH1 D;  2MCZ A;  4AYE A;  4F4O C;  1ELV A;  2RL0 A;  4J38 B;  4WJG 2;  4YNX A;  1C1Z A;  2CKU A;  4DJZ A;  2YBY A;  2KMS A;  3CAL A;  4AYM A;  4KKD A;  2QY0 A;  3OXU D;  1OJV A;  4MUC A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...