2W80A

Structure of a complex between neisseria meningitidis factor h binding protein and ccps 6-7 of human complement factor h
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
123
structure length
123
Chain Sequence
TLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPTPRCI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
source organism Homo sapiens
publication title Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates.
pubmed doi rcsb
molecule keywords COMPLEMENT FACTOR H
total genus 24
structure length 123
sequence length 123
chains with identical sequence B, E, G
ec nomenclature
pdb deposition date 2009-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2w80A02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2w80A01
1VVCA 5I0QB 1VVDA 1GKGA 2KMSA 3SW0X 4C16A 3OXUD 2XWBF 3ZRZA 1GPZA 1O9AA 2ERJA 2QY0A 4WJG2 2IZ3A 4MUCA 2EHFA 4AYMA 1PPQA 3MQLA 1TPMA 4FXGG 1UOTP 1E88A 2RKYA 2KRIA 4LOTA 1QGBA 1E8BA 3EJHA 1H04P 4IGDA 1G4GA 3INBC 1H2PP 1TPGA 1OK1A 3TVJA 1HFIA 2W81A 2RLPA 3RJ3D 3NFPI 4AYDA 1MD7A 3OP8A 1TPNA 1HFHA 2XRDA 1GHQB 2RLQA 1H2QP 4ONTD 4AYEA 1OJWA 3ZD2A 2LOJA 3IU3I 1G4FA 4ZH1D 2CG7A 3OEDC 1FBRA 4KKDA 1C1ZA 2JGWA 3R62A 4AYIA 1QUBA 1GKNA 3L89M 3KXVA 2BZMA 4J38B 4PZ5A 2XRBA 5HYTB 5HYPA 1LY2A 1HCCA 1CKLA 4B2SA 1MD8A 2WIIC 2MCYA 2G7IA 2B5ID 3GXEA 1SRZA 2V8EA 3T5OA 1OJYA 2IZ4A 1NWVA 4K12A 1Z92B 5FO8C 2XWJI 5HYUB 4YNXA 3CALA 2JRAA 4DJZA 3ERBA 2RKZA 1OK3A 1U5MA 1ZJKA 3ZD1A 2EC3A 1SS2A 1E5GA 2RL0A 4JHSA 3M7PA 3O8EB 5JPMG 2MCZA 1Q3XA 4LOSA 2XQWC 4F4OC 2CKUA 2YBYA 1H03P 1OK2A 5HZPB 1OK9A 3GOVA 3IX0A 1ELVA 4B2RA 2W80A 2YRAA 1OJVA 4CSYA 2CG6A 4A5WB 3KZJA 2JGXA 2A55A 1QO6A 2O39C 2UWNA
chains in the Genus database with same CATH superfamily
1VVCA 5I0QB 1VVDA 1GKGA 2KMSA 3SW0X 4C16A 3OXUD 2XWBF 3ZRZA 1GPZA 1O9AA 2ERJA 2QY0A 4WJG2 2IZ3A 4MUCA 2EHFA 4AYMA 1PPQA 3MQLA 1TPMA 4FXGG 1UOTP 1E88A 2RKYA 2KRIA 4LOTA 1QGBA 1E8BA 3EJHA 3FGTA 3CI0J 1H04P 4IGDA 1G4GA 3INBC 3ZLEA 1H2PP 3F6KA 1TPGA 1OK1A 3TVJA 1HFIA 2W81A 2RLPA 3RJ3D 3NFPI 4AYDA 1MD7A 3NJAA 3OP8A 1TPNA 1HFHA 2XRDA 1GHQB 2RLQA 1H2QP 4ONTD 4AYEA 1OJWA 3ZD2A 2LOJA 3IU3I 1G4FA 4ZH1D 5DN4A 2CG7A 3OEDC 1FBRA 4PO7A 4KKDA 1C1ZA 2JGWA 3R62A 4AYIA 1QUBA 4YIZA 1GKNA 3L89M 3KXVA 2BZMA 4J38B 4PZ5A 2Y8TA 2XRBA 3K3TA 5HYTB 3WSXA 1LY2A 5HYPA 1HCCA 1CKLA 2Y8RA 4B2SA 1MD8A 3VWOA 2WIIC 2MCYA 2G7IA 2B5ID 3GXEA 1SRZA 3FGRA 2V8EA 3T5OA 1OJYA 2IZ4A 4MSLA 1NWVA 4K12A 1Z92B 5DN5A 4APLA 5FO8C 2XWJI 2ZYCA 2I2LA 5HYUB 4YNXA 3CALA 2JRAA 4DJZA 3ERBA 2RKZA 4BWCA 1OK3A 1U5MA 1ZJKA 3ZD1A 2X2ZA 2EC3A 1RLHA 3ZLDA 1SS2A 1E5GA 2RL0A 4JHSA 3M7PA 3O8EB 2Y8SA 5JPMG 2MCZA 4N7EA 1Q3XA 4LOSA 2XQWC 4F4OC 2CKUA 2YBYA 1H03P 1OK2A 5HZPB 1OK9A 3GOVA 3IX0A 1ELVA 3WSYA 4B2RA 2W80A 2YRAA 1OJVA 4CSYA 2CG6A 4A5WB 3KZJA 2JGXA 2A55A 1QO6A 2O39C 2UWNA
chains in the Genus database with same CATH topology
1VVCA 5I0QB 1VVDA 1GKGA 2KMSA 3SW0X 4C16A 3OXUD 2XWBF 3ZRZA 1GPZA 1O9AA 2ERJA 2QY0A 4WJG2 2IZ3A 4MUCA 2EHFA 4AYMA 1PPQA 3MQLA 1TPMA 4FXGG 1UOTP 1E88A 2RKYA 2KRIA 4LOTA 1QGBA 1E8BA 3EJHA 1H04P 4IGDA 1G4GA 3INBC 1H2PP 1TPGA 1OK1A 3TVJA 1HFIA 2W81A 2RLPA 3RJ3D 3NFPI 4AYDA 1MD7A 3OP8A 1TPNA 1HFHA 2XRDA 1GHQB 2RLQA 1H2QP 4ONTD 4AYEA 1OJWA 3ZD2A 2LOJA 3IU3I 1G4FA 4ZH1D 2CG7A 3OEDC 1FBRA 4KKDA 1C1ZA 2JGWA 3R62A 4AYIA 1QUBA 1GKNA 3L89M 3KXVA 2BZMA 4J38B 4PZ5A 2XRBA 5HYTB 5HYPA 1LY2A 1HCCA 1CKLA 4B2SA 1MD8A 2WIIC 2MCYA 2G7IA 2B5ID 3GXEA 1SRZA 2V8EA 3T5OA 1OJYA 2IZ4A 1NWVA 4K12A 1Z92B 5FO8C 2XWJI 5HYUB 4YNXA 3CALA 2JRAA 4DJZA 3ERBA 2RKZA 1OK3A 1U5MA 1ZJKA 3ZD1A 2EC3A 1SS2A 1E5GA 2RL0A 4JHSA 3M7PA 3O8EB 5JPMG 2MCZA 1Q3XA 4LOSA 2XQWC 4F4OC 2CKUA 2YBYA 1H03P 1OK2A 5HZPB 1OK9A 3GOVA 3IX0A 1ELVA 4B2RA 2W80A 2YRAA 1OJVA 4CSYA 2CG6A 4A5WB 3KZJA 2JGXA 2A55A 1QO6A 2O39C 2UWNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VVC A;  5I0Q B;  1VVD A;  1GKG A;  2KMS A;  3SW0 X;  4C16 A;  3OXU D;  2XWB F;  3ZRZ A;  1GPZ A;  1O9A A;  2ERJ A;  2QY0 A;  4WJG 2;  2IZ3 A;  4MUC A;  2EHF A;  4AYM A;  1PPQ A;  3MQL A;  1TPM A;  4FXG G;  1UOT P;  1E88 A;  2RKY A;  2KRI A;  4LOT A;  1QGB A;  1E8B A;  3EJH A;  1H04 P;  4IGD A;  1G4G A;  3INB C;  1H2P P;  1TPG A;  1OK1 A;  3TVJ A;  1HFI A;  2W81 A;  2RLP A;  3RJ3 D;  3NFP I;  4AYD A;  1MD7 A;  3OP8 A;  1TPN A;  1HFH A;  2XRD A;  1GHQ B;  2RLQ A;  1H2Q P;  4ONT D;  4AYE A;  1OJW A;  3ZD2 A;  2LOJ A;  3IU3 I;  1G4F A;  4ZH1 D;  2CG7 A;  3OED C;  1FBR A;  4KKD A;  1C1Z A;  2JGW A;  3R62 A;  4AYI A;  1QUB A;  1GKN A;  3L89 M;  3KXV A;  2BZM A;  4J38 B;  4PZ5 A;  2XRB A;  5HYT B;  5HYP A;  1LY2 A;  1HCC A;  1CKL A;  4B2S A;  1MD8 A;  2WII C;  2MCY A;  2G7I A;  2B5I D;  3GXE A;  1SRZ A;  2V8E A;  3T5O A;  1OJY A;  2IZ4 A;  1NWV A;  4K12 A;  1Z92 B;  5FO8 C;  2XWJ I;  5HYU B;  4YNX A;  3CAL A;  2JRA A;  4DJZ A;  3ERB A;  2RKZ A;  1OK3 A;  1U5M A;  1ZJK A;  3ZD1 A;  2EC3 A;  1SS2 A;  1E5G A;  2RL0 A;  4JHS A;  3M7P A;  3O8E B;  5JPM G;  2MCZ A;  1Q3X A;  4LOS A;  2XQW C;  4F4O C;  2CKU A;  2YBY A;  1H03 P;  1OK2 A;  5HZP B;  1OK9 A;  3GOV A;  3IX0 A;  1ELV A;  4B2R A;  2W80 A;  2YRA A;  1OJV A;  4CSY A;  2CG6 A;  4A5W B;  3KZJ A;  2JGX A;  2A55 A;  1QO6 A;  2O39 C;  2UWN A; 
#chains in the Genus database with same CATH topology
 1VVC A;  5I0Q B;  1VVD A;  1GKG A;  2KMS A;  3SW0 X;  4C16 A;  3OXU D;  2XWB F;  3ZRZ A;  1GPZ A;  1O9A A;  2ERJ A;  2QY0 A;  4WJG 2;  2IZ3 A;  4MUC A;  2EHF A;  4AYM A;  1PPQ A;  3MQL A;  1TPM A;  4FXG G;  1UOT P;  1E88 A;  2RKY A;  2KRI A;  4LOT A;  1QGB A;  1E8B A;  3EJH A;  3FGT A;  3CI0 J;  1H04 P;  4IGD A;  1G4G A;  3INB C;  3ZLE A;  1H2P P;  3F6K A;  1TPG A;  1OK1 A;  3TVJ A;  1HFI A;  2W81 A;  2RLP A;  3RJ3 D;  3NFP I;  4AYD A;  1MD7 A;  3NJA A;  3OP8 A;  1TPN A;  1HFH A;  2XRD A;  1GHQ B;  2RLQ A;  1H2Q P;  4ONT D;  4AYE A;  1OJW A;  3ZD2 A;  2LOJ A;  3IU3 I;  1G4F A;  4ZH1 D;  5DN4 A;  2CG7 A;  3OED C;  1FBR A;  4PO7 A;  4KKD A;  1C1Z A;  2JGW A;  3R62 A;  4AYI A;  1QUB A;  4YIZ A;  1GKN A;  3L89 M;  3KXV A;  2BZM A;  4J38 B;  4PZ5 A;  2Y8T A;  2XRB A;  3K3T A;  5HYT B;  3WSX A;  1LY2 A;  5HYP A;  1HCC A;  1CKL A;  2Y8R A;  4B2S A;  1MD8 A;  3VWO A;  2WII C;  2MCY A;  2G7I A;  2B5I D;  3GXE A;  1SRZ A;  3FGR A;  2V8E A;  3T5O A;  1OJY A;  2IZ4 A;  4MSL A;  1NWV A;  4K12 A;  1Z92 B;  5DN5 A;  4APL A;  5FO8 C;  2XWJ I;  2ZYC A;  2I2L A;  5HYU B;  4YNX A;  3CAL A;  2JRA A;  4DJZ A;  3ERB A;  2RKZ A;  4BWC A;  1OK3 A;  1U5M A;  1ZJK A;  3ZD1 A;  2X2Z A;  2EC3 A;  1RLH A;  3ZLD A;  1SS2 A;  1E5G A;  2RL0 A;  4JHS A;  3M7P A;  3O8E B;  2Y8S A;  5JPM G;  2MCZ A;  4N7E A;  1Q3X A;  4LOS A;  2XQW C;  4F4O C;  2CKU A;  2YBY A;  1H03 P;  1OK2 A;  5HZP B;  1OK9 A;  3GOV A;  3IX0 A;  1ELV A;  3WSY A;  4B2R A;  2W80 A;  2YRA A;  1OJV A;  4CSY A;  2CG6 A;  4A5W B;  3KZJ A;  2JGX A;  2A55 A;  1QO6 A;  2O39 C;  2UWN A; 
#chains in the Genus database with same CATH homology
 1VVC A;  5I0Q B;  1VVD A;  1GKG A;  2KMS A;  3SW0 X;  4C16 A;  3OXU D;  2XWB F;  3ZRZ A;  1GPZ A;  1O9A A;  2ERJ A;  2QY0 A;  4WJG 2;  2IZ3 A;  4MUC A;  2EHF A;  4AYM A;  1PPQ A;  3MQL A;  1TPM A;  4FXG G;  1UOT P;  1E88 A;  2RKY A;  2KRI A;  4LOT A;  1QGB A;  1E8B A;  3EJH A;  1H04 P;  4IGD A;  1G4G A;  3INB C;  1H2P P;  1TPG A;  1OK1 A;  3TVJ A;  1HFI A;  2W81 A;  2RLP A;  3RJ3 D;  3NFP I;  4AYD A;  1MD7 A;  3OP8 A;  1TPN A;  1HFH A;  2XRD A;  1GHQ B;  2RLQ A;  1H2Q P;  4ONT D;  4AYE A;  1OJW A;  3ZD2 A;  2LOJ A;  3IU3 I;  1G4F A;  4ZH1 D;  2CG7 A;  3OED C;  1FBR A;  4KKD A;  1C1Z A;  2JGW A;  3R62 A;  4AYI A;  1QUB A;  1GKN A;  3L89 M;  3KXV A;  2BZM A;  4J38 B;  4PZ5 A;  2XRB A;  5HYT B;  5HYP A;  1LY2 A;  1HCC A;  1CKL A;  4B2S A;  1MD8 A;  2WII C;  2MCY A;  2G7I A;  2B5I D;  3GXE A;  1SRZ A;  2V8E A;  3T5O A;  1OJY A;  2IZ4 A;  1NWV A;  4K12 A;  1Z92 B;  5FO8 C;  2XWJ I;  5HYU B;  4YNX A;  3CAL A;  2JRA A;  4DJZ A;  3ERB A;  2RKZ A;  1OK3 A;  1U5M A;  1ZJK A;  3ZD1 A;  2EC3 A;  1SS2 A;  1E5G A;  2RL0 A;  4JHS A;  3M7P A;  3O8E B;  5JPM G;  2MCZ A;  1Q3X A;  4LOS A;  2XQW C;  4F4O C;  2CKU A;  2YBY A;  1H03 P;  1OK2 A;  5HZP B;  1OK9 A;  3GOV A;  3IX0 A;  1ELV A;  4B2R A;  2W80 A;  2YRA A;  1OJV A;  4CSY A;  2CG6 A;  4A5W B;  3KZJ A;  2JGX A;  2A55 A;  1QO6 A;  2O39 C;  2UWN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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