2W81A

Structure of a complex between neisseria meningitidis factor h binding protein and ccps 6-7 of human complement factor h
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
119
structure length
115
Chain Sequence
CDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKSIDVACHYALKAQTVTCMENGWSPTPRCI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
source organism Homo sapiens
publication title Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates.
pubmed doi rcsb
molecule keywords COMPLEMENT FACTOR H
total genus 24
structure length 115
sequence length 119
chains with identical sequence B, E
ec nomenclature
pdb deposition date 2009-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2w81A02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2w81A01
1TPMA 2JGXA 1GKNA 2RKZA 1OJVA 2LOJA 5JPMG 1QUBA 2CKUA 2RLQA 2XWJI 4F4OC 1H04P 1OJWA 1TPNA 1C1ZA 3INBC 2CG7A 4PZ5A 3O8EB 3RJ3D 3TVJA 4B2RA 1ELVA 1H03P 2B5ID 3NFPI 2MCYA 1QO6A 2XQWC 3GXEA 1NWVA 2IZ3A 4A5WB 2WIIC 4FXGG 1MD8A 3M7PA 1TPGA 2BZMA 2JRAA 2MCZA 3R62A 4AYIA 4MUCA 1GHQB 2KMSA 4C16A 3CALA 2A55A 5HYTB 2W80A 3ZD2A 4AYDA 3GOVA 2XRDA 4WJG2 2EC3A 1HCCA 1E8BA 3ERBA 1FBRA 1VVCA 2UWNA 2JGWA 1LY2A 3L89M 1CKLA 1G4GA 3MQLA 2O39C 4KKDA 2W81A 2XRBA 4K12A 3ZRZA 3KZJA 3T5OA 3ZD1A 1GPZA 1U5MA 2G7IA 4ONTD 4AYMA 3SW0X 4LOSA 1H2QP 1OK2A 2ERJA 1E5GA 1SS2A 2IZ4A 1PPQA 1E88A 2QY0A 2RL0A 1G4FA 3KXVA 1GKGA 1OK1A 2KRIA 2RKYA 4IGDA 1OK9A 1HFHA 2EHFA 1OJYA 2CG6A 3EJHA 1H2PP 4J38B 2XWBF 5FO8C 1OK3A 1UOTP 2V8EA 3IU3I 4AYEA 5HYPA 4DJZA 1QGBA 2YRAA 1VVDA 1Z92B 5HYUB 2RLPA 4LOTA 4B2SA 5HZPB 1SRZA 3OP8A 3IX0A 4YNXA 5I0QB 2YBYA 4ZH1D 3OEDC 3OXUD 1ZJKA 4JHSA 1O9AA 1Q3XA 1MD7A 1HFIA 4CSYA
chains in the Genus database with same CATH superfamily
1TPMA 2JGXA 2X2ZA 1GKNA 2RKZA 1OJVA 2LOJA 5JPMG 1QUBA 2CKUA 2RLQA 2XWJI 4F4OC 1H04P 1OJWA 1TPNA 1C1ZA 3INBC 2CG7A 3ZLEA 4PZ5A 3O8EB 3RJ3D 3TVJA 4YIZA 4B2RA 1ELVA 1H03P 2B5ID 3NFPI 2MCYA 5DN5A 1QO6A 2XQWC 3GXEA 1NWVA 4BWCA 2IZ3A 3VWOA 4A5WB 2Y8RA 2WIIC 4FXGG 1MD8A 3M7PA 1TPGA 2BZMA 2JRAA 2MCZA 3R62A 4AYIA 4MUCA 1GHQB 2KMSA 1RLHA 4C16A 2I2LA 3CALA 2A55A 5HYTB 2W80A 4MSLA 3ZD2A 4AYDA 3GOVA 2XRDA 4WJG2 2EC3A 1HCCA 1E8BA 3NJAA 3ERBA 1FBRA 1VVCA 2UWNA 2JGWA 1LY2A 3L89M 1CKLA 1G4GA 3MQLA 2O39C 4KKDA 2W81A 2XRBA 4K12A 5DN4A 3ZRZA 2Y8TA 3KZJA 3T5OA 3ZD1A 3F6KA 1GPZA 1U5MA 2G7IA 3FGRA 4ONTD 4AYMA 3SW0X 3WSXA 4LOSA 2Y8SA 4PO7A 1H2QP 1OK2A 2ERJA 3CI0J 4N7EA 1E5GA 1SS2A 2IZ4A 1PPQA 1E88A 2QY0A 2RL0A 1G4FA 3KXVA 1GKGA 1OK1A 2KRIA 2RKYA 4IGDA 1OK9A 1HFHA 2EHFA 1OJYA 2CG6A 3EJHA 1H2PP 4J38B 2XWBF 5FO8C 1OK3A 1UOTP 3K3TA 2V8EA 3IU3I 4AYEA 3WSYA 5HYPA 4DJZA 1QGBA 2YRAA 1VVDA 3ZLDA 1Z92B 5HYUB 2RLPA 4LOTA 4APLA 4B2SA 5HZPB 1SRZA 3OP8A 3IX0A 4YNXA 5I0QB 2YBYA 4ZH1D 3OEDC 3OXUD 1ZJKA 3FGTA 4JHSA 1O9AA 1Q3XA 1MD7A 2ZYCA 1HFIA 4CSYA
chains in the Genus database with same CATH topology
1TPMA 2JGXA 1GKNA 2RKZA 1OJVA 2LOJA 5JPMG 1QUBA 2CKUA 2RLQA 2XWJI 4F4OC 1H04P 1OJWA 1TPNA 1C1ZA 3INBC 2CG7A 4PZ5A 3O8EB 3RJ3D 3TVJA 4B2RA 1ELVA 1H03P 2B5ID 3NFPI 2MCYA 1QO6A 2XQWC 3GXEA 1NWVA 2IZ3A 4A5WB 2WIIC 4FXGG 1MD8A 3M7PA 1TPGA 2BZMA 2JRAA 2MCZA 3R62A 4AYIA 4MUCA 1GHQB 2KMSA 4C16A 3CALA 2A55A 5HYTB 2W80A 3ZD2A 4AYDA 3GOVA 2XRDA 4WJG2 2EC3A 1HCCA 1E8BA 3ERBA 1FBRA 1VVCA 2UWNA 2JGWA 1LY2A 3L89M 1CKLA 1G4GA 3MQLA 2O39C 4KKDA 2W81A 2XRBA 4K12A 3ZRZA 3KZJA 3T5OA 3ZD1A 1GPZA 1U5MA 2G7IA 4ONTD 4AYMA 3SW0X 4LOSA 1H2QP 1OK2A 2ERJA 1E5GA 1SS2A 2IZ4A 1PPQA 1E88A 2QY0A 2RL0A 1G4FA 3KXVA 1GKGA 1OK1A 2KRIA 2RKYA 4IGDA 1OK9A 1HFHA 2EHFA 1OJYA 2CG6A 3EJHA 1H2PP 4J38B 2XWBF 5FO8C 1OK3A 1UOTP 2V8EA 3IU3I 4AYEA 5HYPA 4DJZA 1QGBA 2YRAA 1VVDA 1Z92B 5HYUB 2RLPA 4LOTA 4B2SA 5HZPB 1SRZA 3OP8A 3IX0A 4YNXA 5I0QB 2YBYA 4ZH1D 3OEDC 3OXUD 1ZJKA 4JHSA 1O9AA 1Q3XA 1MD7A 1HFIA 4CSYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TPM A;  2JGX A;  1GKN A;  2RKZ A;  1OJV A;  2LOJ A;  5JPM G;  1QUB A;  2CKU A;  2RLQ A;  2XWJ I;  4F4O C;  1H04 P;  1OJW A;  1TPN A;  1C1Z A;  3INB C;  2CG7 A;  4PZ5 A;  3O8E B;  3RJ3 D;  3TVJ A;  4B2R A;  1ELV A;  1H03 P;  2B5I D;  3NFP I;  2MCY A;  1QO6 A;  2XQW C;  3GXE A;  1NWV A;  2IZ3 A;  4A5W B;  2WII C;  4FXG G;  1MD8 A;  3M7P A;  1TPG A;  2BZM A;  2JRA A;  2MCZ A;  3R62 A;  4AYI A;  4MUC A;  1GHQ B;  2KMS A;  4C16 A;  3CAL A;  2A55 A;  5HYT B;  2W80 A;  3ZD2 A;  4AYD A;  3GOV A;  2XRD A;  4WJG 2;  2EC3 A;  1HCC A;  1E8B A;  3ERB A;  1FBR A;  1VVC A;  2UWN A;  2JGW A;  1LY2 A;  3L89 M;  1CKL A;  1G4G A;  3MQL A;  2O39 C;  4KKD A;  2W81 A;  2XRB A;  4K12 A;  3ZRZ A;  3KZJ A;  3T5O A;  3ZD1 A;  1GPZ A;  1U5M A;  2G7I A;  4ONT D;  4AYM A;  3SW0 X;  4LOS A;  1H2Q P;  1OK2 A;  2ERJ A;  1E5G A;  1SS2 A;  2IZ4 A;  1PPQ A;  1E88 A;  2QY0 A;  2RL0 A;  1G4F A;  3KXV A;  1GKG A;  1OK1 A;  2KRI A;  2RKY A;  4IGD A;  1OK9 A;  1HFH A;  2EHF A;  1OJY A;  2CG6 A;  3EJH A;  1H2P P;  4J38 B;  2XWB F;  5FO8 C;  1OK3 A;  1UOT P;  2V8E A;  3IU3 I;  4AYE A;  5HYP A;  4DJZ A;  1QGB A;  2YRA A;  1VVD A;  1Z92 B;  5HYU B;  2RLP A;  4LOT A;  4B2S A;  5HZP B;  1SRZ A;  3OP8 A;  3IX0 A;  4YNX A;  5I0Q B;  2YBY A;  4ZH1 D;  3OED C;  3OXU D;  1ZJK A;  4JHS A;  1O9A A;  1Q3X A;  1MD7 A;  1HFI A;  4CSY A; 
#chains in the Genus database with same CATH topology
 1TPM A;  2JGX A;  2X2Z A;  1GKN A;  2RKZ A;  1OJV A;  2LOJ A;  5JPM G;  1QUB A;  2CKU A;  2RLQ A;  2XWJ I;  4F4O C;  1H04 P;  1OJW A;  1TPN A;  1C1Z A;  3INB C;  2CG7 A;  3ZLE A;  4PZ5 A;  3O8E B;  3RJ3 D;  3TVJ A;  4YIZ A;  4B2R A;  1ELV A;  1H03 P;  2B5I D;  3NFP I;  2MCY A;  5DN5 A;  1QO6 A;  2XQW C;  3GXE A;  1NWV A;  4BWC A;  2IZ3 A;  3VWO A;  4A5W B;  2Y8R A;  2WII C;  4FXG G;  1MD8 A;  3M7P A;  1TPG A;  2BZM A;  2JRA A;  2MCZ A;  3R62 A;  4AYI A;  4MUC A;  1GHQ B;  2KMS A;  1RLH A;  4C16 A;  2I2L A;  3CAL A;  2A55 A;  5HYT B;  2W80 A;  4MSL A;  3ZD2 A;  4AYD A;  3GOV A;  2XRD A;  4WJG 2;  2EC3 A;  1HCC A;  1E8B A;  3NJA A;  3ERB A;  1FBR A;  1VVC A;  2UWN A;  2JGW A;  1LY2 A;  3L89 M;  1CKL A;  1G4G A;  3MQL A;  2O39 C;  4KKD A;  2W81 A;  2XRB A;  4K12 A;  5DN4 A;  3ZRZ A;  2Y8T A;  3KZJ A;  3T5O A;  3ZD1 A;  3F6K A;  1GPZ A;  1U5M A;  2G7I A;  3FGR A;  4ONT D;  4AYM A;  3SW0 X;  3WSX A;  4LOS A;  2Y8S A;  4PO7 A;  1H2Q P;  1OK2 A;  2ERJ A;  3CI0 J;  4N7E A;  1E5G A;  1SS2 A;  2IZ4 A;  1PPQ A;  1E88 A;  2QY0 A;  2RL0 A;  1G4F A;  3KXV A;  1GKG A;  1OK1 A;  2KRI A;  2RKY A;  4IGD A;  1OK9 A;  1HFH A;  2EHF A;  1OJY A;  2CG6 A;  3EJH A;  1H2P P;  4J38 B;  2XWB F;  5FO8 C;  1OK3 A;  1UOT P;  3K3T A;  2V8E A;  3IU3 I;  4AYE A;  3WSY A;  5HYP A;  4DJZ A;  1QGB A;  2YRA A;  1VVD A;  3ZLD A;  1Z92 B;  5HYU B;  2RLP A;  4LOT A;  4APL A;  4B2S A;  5HZP B;  1SRZ A;  3OP8 A;  3IX0 A;  4YNX A;  5I0Q B;  2YBY A;  4ZH1 D;  3OED C;  3OXU D;  1ZJK A;  3FGT A;  4JHS A;  1O9A A;  1Q3X A;  1MD7 A;  2ZYC A;  1HFI A;  4CSY A; 
#chains in the Genus database with same CATH homology
 1TPM A;  2JGX A;  1GKN A;  2RKZ A;  1OJV A;  2LOJ A;  5JPM G;  1QUB A;  2CKU A;  2RLQ A;  2XWJ I;  4F4O C;  1H04 P;  1OJW A;  1TPN A;  1C1Z A;  3INB C;  2CG7 A;  4PZ5 A;  3O8E B;  3RJ3 D;  3TVJ A;  4B2R A;  1ELV A;  1H03 P;  2B5I D;  3NFP I;  2MCY A;  1QO6 A;  2XQW C;  3GXE A;  1NWV A;  2IZ3 A;  4A5W B;  2WII C;  4FXG G;  1MD8 A;  3M7P A;  1TPG A;  2BZM A;  2JRA A;  2MCZ A;  3R62 A;  4AYI A;  4MUC A;  1GHQ B;  2KMS A;  4C16 A;  3CAL A;  2A55 A;  5HYT B;  2W80 A;  3ZD2 A;  4AYD A;  3GOV A;  2XRD A;  4WJG 2;  2EC3 A;  1HCC A;  1E8B A;  3ERB A;  1FBR A;  1VVC A;  2UWN A;  2JGW A;  1LY2 A;  3L89 M;  1CKL A;  1G4G A;  3MQL A;  2O39 C;  4KKD A;  2W81 A;  2XRB A;  4K12 A;  3ZRZ A;  3KZJ A;  3T5O A;  3ZD1 A;  1GPZ A;  1U5M A;  2G7I A;  4ONT D;  4AYM A;  3SW0 X;  4LOS A;  1H2Q P;  1OK2 A;  2ERJ A;  1E5G A;  1SS2 A;  2IZ4 A;  1PPQ A;  1E88 A;  2QY0 A;  2RL0 A;  1G4F A;  3KXV A;  1GKG A;  1OK1 A;  2KRI A;  2RKY A;  4IGD A;  1OK9 A;  1HFH A;  2EHF A;  1OJY A;  2CG6 A;  3EJH A;  1H2P P;  4J38 B;  2XWB F;  5FO8 C;  1OK3 A;  1UOT P;  2V8E A;  3IU3 I;  4AYE A;  5HYP A;  4DJZ A;  1QGB A;  2YRA A;  1VVD A;  1Z92 B;  5HYU B;  2RLP A;  4LOT A;  4B2S A;  5HZP B;  1SRZ A;  3OP8 A;  3IX0 A;  4YNX A;  5I0Q B;  2YBY A;  4ZH1 D;  3OED C;  3OXU D;  1ZJK A;  4JHS A;  1O9A A;  1Q3X A;  1MD7 A;  1HFI A;  4CSY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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