2Y8SA

Co-structure of an ama1 mutant (y230a) with a surface exposed region of ron2 from toxoplasma gondii
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
411
structure length
386
Chain Sequence
GNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILAVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDCTADEQNEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of Ama1 with a Ron2 Peptide
pubmed doi rcsb
molecule tags Membrane protein
source organism Toxoplasma gondii
molecule keywords APICAL MEMBRANE ANTIGEN, PUTATIVE
total genus 97
structure length 386
sequence length 411
chains with identical sequence D
ec nomenclature
pdb deposition date 2011-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 2y8sA03
2Y8SA 4YIZA 3ZLEA 3ZLDA 4APLA 2Y8RA 2Y8TA 2X2ZA
chains in the Genus database with same CATH superfamily
2XWJI 3KZJA 3K3TA 1E8BA 1C1ZA 1G4GA 1OK3A 5FO8C 2WIIC 4F4OC 5HYPA 1HFHA 2CG7A 1E5GA 3MQLA 3VWOA 2EC3A 4A5WB 2JGXA 1GPZA 3ERBA 1GKNA 1TPMA 5HZPB 1TPGA 2XQWC 2O39C 2EHFA 3ZD2A 1GKGA 2XRDA 4PZ5A 4LOSA 2IZ3A 1O9AA 2XRBA 3R62A 3M7PA 2LOJA 1LY2A 1H2QP 2YRAA 4K12A 3WSYA 1Q3XA 3IX0A 5I0QB 2W81A 3OEDC 1U5MA 4PO7A 2BZMA 3OXUD 4B2RA 1MD7A 2IZ4A 1VVDA 5DN5A 1E88A 4APLA 2Y8RA 3GXEA 3WSXA 2RKZA 4ZH1D 2Y8TA 5DN4A 1SS2A 4ONTD 2JRAA 3TVJA 3F6KA 2CKUA 5JPMG 3NJAA 1QO6A 1OK9A 3O8EB 2CG6A 2KMSA 3ZD1A 4YIZA 1VVCA 2MCZA 1OJVA 1ZJKA 2B5ID 2RLPA 2JGWA 1OK2A 2YBYA 4FXGG 3RJ3D 2X2ZA 2ZYCA 3KXVA 3OP8A 4B2SA 1CKLA 4AYMA 1QGBA 2MCYA 1OJWA 4LOTA 4JHSA 4YNXA 5HYTB 4MSLA 1QUBA 1Z92B 4C16A 1UOTP 1H03P 4J38B 3ZLEA 2XWBF 3FGRA 1FBRA 3GOVA 4CSYA 3CALA 4AYDA 1PPQA 4AYEA 1HFIA 2RL0A 3INBC 4IGDA 1OJYA 2RKYA 1H04P 1H2PP 4DJZA 3EJHA 1NWVA 2KRIA 1TPNA 3T5OA 2V8EA 1G4FA 2RLQA 3ZLDA 3L89M 2QY0A 1MD8A 4N7EA 2Y8SA 4KKDA 4MUCA 3SW0X 4BWCA 2A55A 2UWNA 3ZRZA 1HCCA 1OK1A 4AYIA 4WJG2 5HYUB 1SRZA 3FGTA 1GHQB 2W80A 3IU3I 2G7IA 3NFPI 2ERJA 2I2LA 1RLHA 1ELVA 3CI0J
chains in the Genus database with same CATH topology
4PO7A 4YIZA 3ZLDA 4APLA 2Y8RA 2X2ZA 4N7EA 2Y8SA 4BWCA 3WSXA 2Y8TA 4MSLA 3ZLEA 3FGRA 3FGTA 3F6KA 3NJAA 2I2LA 3WSYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y8S A;  4YIZ A;  3ZLE A;  3ZLD A;  4APL A;  2Y8R A;  2Y8T A;  2X2Z A; 
#chains in the Genus database with same CATH topology
 2XWJ I;  3KZJ A;  3K3T A;  1E8B A;  1C1Z A;  1G4G A;  1OK3 A;  5FO8 C;  2WII C;  4F4O C;  5HYP A;  1HFH A;  2CG7 A;  1E5G A;  3MQL A;  3VWO A;  2EC3 A;  4A5W B;  2JGX A;  1GPZ A;  3ERB A;  1GKN A;  1TPM A;  5HZP B;  1TPG A;  2XQW C;  2O39 C;  2EHF A;  3ZD2 A;  1GKG A;  2XRD A;  4PZ5 A;  4LOS A;  2IZ3 A;  1O9A A;  2XRB A;  3R62 A;  3M7P A;  2LOJ A;  1LY2 A;  1H2Q P;  2YRA A;  4K12 A;  3WSY A;  1Q3X A;  3IX0 A;  5I0Q B;  2W81 A;  3OED C;  1U5M A;  4PO7 A;  2BZM A;  3OXU D;  4B2R A;  1MD7 A;  2IZ4 A;  1VVD A;  5DN5 A;  1E88 A;  4APL A;  2Y8R A;  3GXE A;  3WSX A;  2RKZ A;  4ZH1 D;  2Y8T A;  5DN4 A;  1SS2 A;  4ONT D;  2JRA A;  3TVJ A;  3F6K A;  2CKU A;  5JPM G;  3NJA A;  1QO6 A;  1OK9 A;  3O8E B;  2CG6 A;  2KMS A;  3ZD1 A;  4YIZ A;  1VVC A;  2MCZ A;  1OJV A;  1ZJK A;  2B5I D;  2RLP A;  2JGW A;  1OK2 A;  2YBY A;  4FXG G;  3RJ3 D;  2X2Z A;  2ZYC A;  3KXV A;  3OP8 A;  4B2S A;  1CKL A;  4AYM A;  1QGB A;  2MCY A;  1OJW A;  4LOT A;  4JHS A;  4YNX A;  5HYT B;  4MSL A;  1QUB A;  1Z92 B;  4C16 A;  1UOT P;  1H03 P;  4J38 B;  3ZLE A;  2XWB F;  3FGR A;  1FBR A;  3GOV A;  4CSY A;  3CAL A;  4AYD A;  1PPQ A;  4AYE A;  1HFI A;  2RL0 A;  3INB C;  4IGD A;  1OJY A;  2RKY A;  1H04 P;  1H2P P;  4DJZ A;  3EJH A;  1NWV A;  2KRI A;  1TPN A;  3T5O A;  2V8E A;  1G4F A;  2RLQ A;  3ZLD A;  3L89 M;  2QY0 A;  1MD8 A;  4N7E A;  2Y8S A;  4KKD A;  4MUC A;  3SW0 X;  4BWC A;  2A55 A;  2UWN A;  3ZRZ A;  1HCC A;  1OK1 A;  4AYI A;  4WJG 2;  5HYU B;  1SRZ A;  3FGT A;  1GHQ B;  2W80 A;  3IU3 I;  2G7I A;  3NFP I;  2ERJ A;  2I2L A;  1RLH A;  1ELV A;  3CI0 J; 
#chains in the Genus database with same CATH homology
 4PO7 A;  4YIZ A;  3ZLD A;  4APL A;  2Y8R A;  2X2Z A;  4N7E A;  2Y8S A;  4BWC A;  3WSX A;  2Y8T A;  4MSL A;  3ZLE A;  3FGR A;  3FGT A;  3F6K A;  3NJA A;  2I2L A;  3WSY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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