2Y8SA

Co-structure of an ama1 mutant (y230a) with a surface exposed region of ron2 from toxoplasma gondii
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
411
structure length
386
Chain Sequence
GNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILAVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDCTADEQNEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of Ama1 with a Ron2 Peptide
pubmed doi rcsb
molecule tags Membrane protein
source organism Toxoplasma gondii
molecule keywords APICAL MEMBRANE ANTIGEN, PUTATIVE
total genus 97
structure length 386
sequence length 411
chains with identical sequence D
ec nomenclature
pdb deposition date 2011-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 2y8sA03
2Y8SA 2X2ZA 4YIZA 2Y8TA 3ZLEA 2Y8RA 3ZLDA 4APLA
chains in the Genus database with same CATH superfamily
2XWJI 3ZRZA 1OK3A 2JRAA 2KMSA 1O9AA 1OK2A 1TPNA 3OP8A 4C16A 3NFPI 1TPMA 2CG7A 4WJG2 3MQLA 1H2PP 3IX0A 5DN4A 3WSXA 2CG6A 3RJ3D 3KXVA 2ERJA 2QY0A 4J38B 2W81A 3O8EB 3K3TA 4YNXA 1GHQB 2ZYCA 2XRDA 1ZJKA 2B5ID 3INBC 1H2QP 1UOTP 3WSYA 2BZMA 3VWOA 1OJVA 3ZLEA 3L89M 2IZ4A 3T5OA 4B2RA 5HYPA 4ONTD 1U5MA 2O39C 4DJZA 1E88A 1Q3XA 1TPGA 2A55A 3ZD1A 1FBRA 1GKGA 2JGXA 2MCZA 1OJWA 4KKDA 3NJAA 2I2LA 4APLA 2X2ZA 4AYIA 1H04P 2EHFA 1SS2A 4BWCA 3TVJA 2JGWA 4JHSA 1H03P 1G4FA 1MD7A 1PPQA 1QGBA 2W80A 1OK1A 3F6KA 1E5GA 1MD8A 4ZH1D 4MSLA 1QO6A 5FO8C 3GOVA 2YRAA 2Y8RA 5HYUB 1E8BA 1OJYA 3CALA 1VVCA 3EJHA 2Y8TA 5HYTB 5I0QB 1SRZA 1LY2A 2RL0A 3GXEA 2XQWC 4B2SA 4YIZA 1C1ZA 2RLPA 4MUCA 4FXGG 1NWVA 5DN5A 1RLHA 3R62A 2XRBA 2Y8SA 2UWNA 1HCCA 2RLQA 3ERBA 1ELVA 4K12A 1G4GA 1VVDA 2G7IA 2IZ3A 3OEDC 3FGTA 4IGDA 5JPMG 3ZLDA 4LOTA 3M7PA 4AYEA 3IU3I 4CSYA 5HZPB 2MCYA 1GPZA 1OK9A 2RKYA 3KZJA 3SW0X 2LOJA 1Z92B 4A5WB 4AYDA 2EC3A 2XWBF 2YBYA 1HFIA 2CKUA 3OXUD 1HFHA 4LOSA 2WIIC 1CKLA 1GKNA 4AYMA 4PZ5A 4PO7A 3FGRA 3ZD2A 4F4OC 3CI0J 1QUBA 2RKZA 4N7EA 2KRIA 2V8EA
chains in the Genus database with same CATH topology
2Y8TA 4YIZA 4APLA 2I2LA 2Y8SA 2X2ZA 3WSXA 3NJAA 4BWCA 2Y8RA 4PO7A 3FGRA 3F6KA 3FGTA 4MSLA 3ZLEA 3WSYA 4N7EA 3ZLDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y8S A;  2X2Z A;  4YIZ A;  2Y8T A;  3ZLE A;  2Y8R A;  3ZLD A;  4APL A; 
#chains in the Genus database with same CATH topology
 2XWJ I;  3ZRZ A;  1OK3 A;  2JRA A;  2KMS A;  1O9A A;  1OK2 A;  1TPN A;  3OP8 A;  4C16 A;  3NFP I;  1TPM A;  2CG7 A;  4WJG 2;  3MQL A;  1H2P P;  3IX0 A;  5DN4 A;  3WSX A;  2CG6 A;  3RJ3 D;  3KXV A;  2ERJ A;  2QY0 A;  4J38 B;  2W81 A;  3O8E B;  3K3T A;  4YNX A;  1GHQ B;  2ZYC A;  2XRD A;  1ZJK A;  2B5I D;  3INB C;  1H2Q P;  1UOT P;  3WSY A;  2BZM A;  3VWO A;  1OJV A;  3ZLE A;  3L89 M;  2IZ4 A;  3T5O A;  4B2R A;  5HYP A;  4ONT D;  1U5M A;  2O39 C;  4DJZ A;  1E88 A;  1Q3X A;  1TPG A;  2A55 A;  3ZD1 A;  1FBR A;  1GKG A;  2JGX A;  2MCZ A;  1OJW A;  4KKD A;  3NJA A;  2I2L A;  4APL A;  2X2Z A;  4AYI A;  1H04 P;  2EHF A;  1SS2 A;  4BWC A;  3TVJ A;  2JGW A;  4JHS A;  1H03 P;  1G4F A;  1MD7 A;  1PPQ A;  1QGB A;  2W80 A;  1OK1 A;  3F6K A;  1E5G A;  1MD8 A;  4ZH1 D;  4MSL A;  1QO6 A;  5FO8 C;  3GOV A;  2YRA A;  2Y8R A;  5HYU B;  1E8B A;  1OJY A;  3CAL A;  1VVC A;  3EJH A;  2Y8T A;  5HYT B;  5I0Q B;  1SRZ A;  1LY2 A;  2RL0 A;  3GXE A;  2XQW C;  4B2S A;  4YIZ A;  1C1Z A;  2RLP A;  4MUC A;  4FXG G;  1NWV A;  5DN5 A;  1RLH A;  3R62 A;  2XRB A;  2Y8S A;  2UWN A;  1HCC A;  2RLQ A;  3ERB A;  1ELV A;  4K12 A;  1G4G A;  1VVD A;  2G7I A;  2IZ3 A;  3OED C;  3FGT A;  4IGD A;  5JPM G;  3ZLD A;  4LOT A;  3M7P A;  4AYE A;  3IU3 I;  4CSY A;  5HZP B;  2MCY A;  1GPZ A;  1OK9 A;  2RKY A;  3KZJ A;  3SW0 X;  2LOJ A;  1Z92 B;  4A5W B;  4AYD A;  2EC3 A;  2XWB F;  2YBY A;  1HFI A;  2CKU A;  3OXU D;  1HFH A;  4LOS A;  2WII C;  1CKL A;  1GKN A;  4AYM A;  4PZ5 A;  4PO7 A;  3FGR A;  3ZD2 A;  4F4O C;  3CI0 J;  1QUB A;  2RKZ A;  4N7E A;  2KRI A;  2V8E A; 
#chains in the Genus database with same CATH homology
 2Y8T A;  4YIZ A;  4APL A;  2I2L A;  2Y8S A;  2X2Z A;  3WSX A;  3NJA A;  4BWC A;  2Y8R A;  4PO7 A;  3FGR A;  3F6K A;  3FGT A;  4MSL A;  3ZLE A;  3WSY A;  4N7E A;  3ZLD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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