2YBYA

Structure of domains 6 and 7 of the mouse complement regulator factor h
Total Genus 22
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
123
structure length
123
Chain Sequence
ALKPCEFPQFKYGRLYYEESLRPNFPVSIGNKYSYKCDNGFSPPSGYSWDYLRCTAQGWEPEVPCVRKCVFHYVENGDSAYWEKVYVQGQSLKVQCYNGYSLQNGQDTMTCTENGWSPPPKCI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
pubmed doi rcsb
molecule tags Immune system
source organism Mus musculus
molecule keywords COMPLEMENT FACTOR H
total genus 22
structure length 123
sequence length 123
ec nomenclature
pdb deposition date 2011-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2ybyA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 2ybyA01
3GOVA 3ZD1A 3KZJA 4A5WB 4PZ5A 1OK3A 2XWJI 4ONTD 3RJ3D 3CALA 4B2SA 3GXEA 5JPMG 1H2PP 1E5GA 1U5MA 1TPGA 1PPQA 3L89M 1HFHA 1SS2A 2XRBA 1OK1A 1FBRA 1C1ZA 2V8EA 3R62A 2YBYA 1OK2A 5HYUB 2XWBF 3ZRZA 4AYEA 3IX0A 1O9AA 1OJYA 4C16A 1Z92B 3OP8A 2JGXA 1GHQB 4DJZA 2KMSA 2A55A 1QUBA 2LOJA 3OEDC 2RLQA 4AYDA 1H2QP 1Q3XA 4WJG2 5HYTB 3KXVA 2XRDA 1TPMA 3IU3I 1QGBA 4IGDA 4AYIA 3SW0X 1GKGA 2G7IA 4ZH1D 3ZD2A 2RL0A 2KRIA 2UWNA 2EHFA 1MD8A 1OJWA 1HFIA 2W80A 4KKDA 4LOTA 1ELVA 1G4FA 1OJVA 4LOSA 1G4GA 1NWVA 4B2RA 2CG6A 1LY2A 2WIIC 3INBC 1ZJKA 2MCYA 4CSYA 1VVDA 2XQWC 2QY0A 1GPZA 2RLPA 1E8BA 4JHSA 3ERBA 1OK9A 3OXUD 2YRAA 1H03P 1TPNA 2O39C 1SRZA 3M7PA 5I0QB 5HYPA 3MQLA 1H04P 1UOTP 4AYMA 3NFPI 2IZ3A 4F4OC 2BZMA 3EJHA 2IZ4A 2RKZA 4K12A 5HZPB 3TVJA 3T5OA 4FXGG 1QO6A 2B5ID 2CG7A 2JGWA 1E88A 1MD7A 2RKYA 2W81A 3O8EB 1HCCA 2ERJA 2MCZA 1GKNA 2CKUA 5FO8C 1CKLA 2JRAA 1VVCA 4YNXA 4MUCA 4J38B 2EC3A
chains in the Genus database with same CATH superfamily
3GOVA 3ZD1A 2Y8TA 3KZJA 4A5WB 4PZ5A 1OK3A 2XWJI 4ONTD 3RJ3D 3CALA 4B2SA 3VWOA 3GXEA 5JPMG 1H2PP 3K3TA 3CI0J 1E5GA 1U5MA 1TPGA 4YIZA 1PPQA 2X2ZA 3L89M 1HFHA 1SS2A 2XRBA 1OK1A 1FBRA 1C1ZA 2V8EA 3R62A 2YBYA 1OK2A 5HYUB 4BWCA 2XWBF 3ZRZA 4AYEA 3IX0A 1O9AA 1OJYA 4C16A 1Z92B 3OP8A 2JGXA 3ZLDA 1GHQB 4DJZA 2KMSA 2A55A 1QUBA 2I2LA 2LOJA 3OEDC 2RLQA 4AYDA 1H2QP 5DN5A 1Q3XA 4WJG2 5HYTB 3KXVA 2XRDA 1TPMA 3IU3I 1QGBA 4IGDA 4AYIA 3SW0X 1GKGA 2G7IA 2Y8RA 4APLA 4ZH1D 3ZD2A 2RL0A 2KRIA 2UWNA 2EHFA 1MD8A 1OJWA 1HFIA 2W80A 4KKDA 4LOTA 1ELVA 1G4FA 1OJVA 4LOSA 1G4GA 1NWVA 4B2RA 2CG6A 1LY2A 2WIIC 3INBC 1ZJKA 1RLHA 2MCYA 4CSYA 4PO7A 1VVDA 2XQWC 2QY0A 1GPZA 2RLPA 1E8BA 4JHSA 3ERBA 1OK9A 3NJAA 2ZYCA 3OXUD 2YRAA 1H03P 3FGRA 1TPNA 2O39C 1SRZA 3M7PA 4MSLA 5HYPA 5I0QB 3FGTA 3MQLA 1H04P 1UOTP 3WSXA 4AYMA 3NFPI 2IZ3A 4F4OC 2BZMA 3EJHA 2IZ4A 2RKZA 4K12A 5HZPB 3ZLEA 3F6KA 3TVJA 3T5OA 4FXGG 3WSYA 1QO6A 2B5ID 2CG7A 2JGWA 5DN4A 1E88A 1MD7A 2RKYA 2W81A 3O8EB 1HCCA 2ERJA 2Y8SA 2MCZA 1GKNA 2CKUA 5FO8C 4N7EA 1CKLA 2JRAA 1VVCA 4YNXA 4MUCA 4J38B 2EC3A
chains in the Genus database with same CATH topology
3GOVA 3ZD1A 3KZJA 4A5WB 4PZ5A 1OK3A 2XWJI 4ONTD 3RJ3D 3CALA 4B2SA 3GXEA 5JPMG 1H2PP 1E5GA 1U5MA 1TPGA 1PPQA 3L89M 1HFHA 1SS2A 2XRBA 1OK1A 1FBRA 1C1ZA 2V8EA 3R62A 2YBYA 1OK2A 5HYUB 2XWBF 3ZRZA 4AYEA 3IX0A 1O9AA 1OJYA 4C16A 1Z92B 3OP8A 2JGXA 1GHQB 4DJZA 2KMSA 2A55A 1QUBA 2LOJA 3OEDC 2RLQA 4AYDA 1H2QP 1Q3XA 4WJG2 5HYTB 3KXVA 2XRDA 1TPMA 3IU3I 1QGBA 4IGDA 4AYIA 3SW0X 1GKGA 2G7IA 4ZH1D 3ZD2A 2RL0A 2KRIA 2UWNA 2EHFA 1MD8A 1OJWA 1HFIA 2W80A 4KKDA 4LOTA 1ELVA 1G4FA 1OJVA 4LOSA 1G4GA 1NWVA 4B2RA 2CG6A 1LY2A 2WIIC 3INBC 1ZJKA 2MCYA 4CSYA 1VVDA 2XQWC 2QY0A 1GPZA 2RLPA 1E8BA 4JHSA 3ERBA 1OK9A 3OXUD 2YRAA 1H03P 1TPNA 2O39C 1SRZA 3M7PA 5I0QB 5HYPA 3MQLA 1H04P 1UOTP 4AYMA 3NFPI 2IZ3A 4F4OC 2BZMA 3EJHA 2IZ4A 2RKZA 4K12A 5HZPB 3TVJA 3T5OA 4FXGG 1QO6A 2B5ID 2CG7A 2JGWA 1E88A 1MD7A 2RKYA 2W81A 3O8EB 1HCCA 2ERJA 2MCZA 1GKNA 2CKUA 5FO8C 1CKLA 2JRAA 1VVCA 4YNXA 4MUCA 4J38B 2EC3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GOV A;  3ZD1 A;  3KZJ A;  4A5W B;  4PZ5 A;  1OK3 A;  2XWJ I;  4ONT D;  3RJ3 D;  3CAL A;  4B2S A;  3GXE A;  5JPM G;  1H2P P;  1E5G A;  1U5M A;  1TPG A;  1PPQ A;  3L89 M;  1HFH A;  1SS2 A;  2XRB A;  1OK1 A;  1FBR A;  1C1Z A;  2V8E A;  3R62 A;  2YBY A;  1OK2 A;  5HYU B;  2XWB F;  3ZRZ A;  4AYE A;  3IX0 A;  1O9A A;  1OJY A;  4C16 A;  1Z92 B;  3OP8 A;  2JGX A;  1GHQ B;  4DJZ A;  2KMS A;  2A55 A;  1QUB A;  2LOJ A;  3OED C;  2RLQ A;  4AYD A;  1H2Q P;  1Q3X A;  4WJG 2;  5HYT B;  3KXV A;  2XRD A;  1TPM A;  3IU3 I;  1QGB A;  4IGD A;  4AYI A;  3SW0 X;  1GKG A;  2G7I A;  4ZH1 D;  3ZD2 A;  2RL0 A;  2KRI A;  2UWN A;  2EHF A;  1MD8 A;  1OJW A;  1HFI A;  2W80 A;  4KKD A;  4LOT A;  1ELV A;  1G4F A;  1OJV A;  4LOS A;  1G4G A;  1NWV A;  4B2R A;  2CG6 A;  1LY2 A;  2WII C;  3INB C;  1ZJK A;  2MCY A;  4CSY A;  1VVD A;  2XQW C;  2QY0 A;  1GPZ A;  2RLP A;  1E8B A;  4JHS A;  3ERB A;  1OK9 A;  3OXU D;  2YRA A;  1H03 P;  1TPN A;  2O39 C;  1SRZ A;  3M7P A;  5I0Q B;  5HYP A;  3MQL A;  1H04 P;  1UOT P;  4AYM A;  3NFP I;  2IZ3 A;  4F4O C;  2BZM A;  3EJH A;  2IZ4 A;  2RKZ A;  4K12 A;  5HZP B;  3TVJ A;  3T5O A;  4FXG G;  1QO6 A;  2B5I D;  2CG7 A;  2JGW A;  1E88 A;  1MD7 A;  2RKY A;  2W81 A;  3O8E B;  1HCC A;  2ERJ A;  2MCZ A;  1GKN A;  2CKU A;  5FO8 C;  1CKL A;  2JRA A;  1VVC A;  4YNX A;  4MUC A;  4J38 B;  2EC3 A; 
#chains in the Genus database with same CATH topology
 3GOV A;  3ZD1 A;  2Y8T A;  3KZJ A;  4A5W B;  4PZ5 A;  1OK3 A;  2XWJ I;  4ONT D;  3RJ3 D;  3CAL A;  4B2S A;  3VWO A;  3GXE A;  5JPM G;  1H2P P;  3K3T A;  3CI0 J;  1E5G A;  1U5M A;  1TPG A;  4YIZ A;  1PPQ A;  2X2Z A;  3L89 M;  1HFH A;  1SS2 A;  2XRB A;  1OK1 A;  1FBR A;  1C1Z A;  2V8E A;  3R62 A;  2YBY A;  1OK2 A;  5HYU B;  4BWC A;  2XWB F;  3ZRZ A;  4AYE A;  3IX0 A;  1O9A A;  1OJY A;  4C16 A;  1Z92 B;  3OP8 A;  2JGX A;  3ZLD A;  1GHQ B;  4DJZ A;  2KMS A;  2A55 A;  1QUB A;  2I2L A;  2LOJ A;  3OED C;  2RLQ A;  4AYD A;  1H2Q P;  5DN5 A;  1Q3X A;  4WJG 2;  5HYT B;  3KXV A;  2XRD A;  1TPM A;  3IU3 I;  1QGB A;  4IGD A;  4AYI A;  3SW0 X;  1GKG A;  2G7I A;  2Y8R A;  4APL A;  4ZH1 D;  3ZD2 A;  2RL0 A;  2KRI A;  2UWN A;  2EHF A;  1MD8 A;  1OJW A;  1HFI A;  2W80 A;  4KKD A;  4LOT A;  1ELV A;  1G4F A;  1OJV A;  4LOS A;  1G4G A;  1NWV A;  4B2R A;  2CG6 A;  1LY2 A;  2WII C;  3INB C;  1ZJK A;  1RLH A;  2MCY A;  4CSY A;  4PO7 A;  1VVD A;  2XQW C;  2QY0 A;  1GPZ A;  2RLP A;  1E8B A;  4JHS A;  3ERB A;  1OK9 A;  3NJA A;  2ZYC A;  3OXU D;  2YRA A;  1H03 P;  3FGR A;  1TPN A;  2O39 C;  1SRZ A;  3M7P A;  4MSL A;  5HYP A;  5I0Q B;  3FGT A;  3MQL A;  1H04 P;  1UOT P;  3WSX A;  4AYM A;  3NFP I;  2IZ3 A;  4F4O C;  2BZM A;  3EJH A;  2IZ4 A;  2RKZ A;  4K12 A;  5HZP B;  3ZLE A;  3F6K A;  3TVJ A;  3T5O A;  4FXG G;  3WSY A;  1QO6 A;  2B5I D;  2CG7 A;  2JGW A;  5DN4 A;  1E88 A;  1MD7 A;  2RKY A;  2W81 A;  3O8E B;  1HCC A;  2ERJ A;  2Y8S A;  2MCZ A;  1GKN A;  2CKU A;  5FO8 C;  4N7E A;  1CKL A;  2JRA A;  1VVC A;  4YNX A;  4MUC A;  4J38 B;  2EC3 A; 
#chains in the Genus database with same CATH homology
 3GOV A;  3ZD1 A;  3KZJ A;  4A5W B;  4PZ5 A;  1OK3 A;  2XWJ I;  4ONT D;  3RJ3 D;  3CAL A;  4B2S A;  3GXE A;  5JPM G;  1H2P P;  1E5G A;  1U5M A;  1TPG A;  1PPQ A;  3L89 M;  1HFH A;  1SS2 A;  2XRB A;  1OK1 A;  1FBR A;  1C1Z A;  2V8E A;  3R62 A;  2YBY A;  1OK2 A;  5HYU B;  2XWB F;  3ZRZ A;  4AYE A;  3IX0 A;  1O9A A;  1OJY A;  4C16 A;  1Z92 B;  3OP8 A;  2JGX A;  1GHQ B;  4DJZ A;  2KMS A;  2A55 A;  1QUB A;  2LOJ A;  3OED C;  2RLQ A;  4AYD A;  1H2Q P;  1Q3X A;  4WJG 2;  5HYT B;  3KXV A;  2XRD A;  1TPM A;  3IU3 I;  1QGB A;  4IGD A;  4AYI A;  3SW0 X;  1GKG A;  2G7I A;  4ZH1 D;  3ZD2 A;  2RL0 A;  2KRI A;  2UWN A;  2EHF A;  1MD8 A;  1OJW A;  1HFI A;  2W80 A;  4KKD A;  4LOT A;  1ELV A;  1G4F A;  1OJV A;  4LOS A;  1G4G A;  1NWV A;  4B2R A;  2CG6 A;  1LY2 A;  2WII C;  3INB C;  1ZJK A;  2MCY A;  4CSY A;  1VVD A;  2XQW C;  2QY0 A;  1GPZ A;  2RLP A;  1E8B A;  4JHS A;  3ERB A;  1OK9 A;  3OXU D;  2YRA A;  1H03 P;  1TPN A;  2O39 C;  1SRZ A;  3M7P A;  5I0Q B;  5HYP A;  3MQL A;  1H04 P;  1UOT P;  4AYM A;  3NFP I;  2IZ3 A;  4F4O C;  2BZM A;  3EJH A;  2IZ4 A;  2RKZ A;  4K12 A;  5HZP B;  3TVJ A;  3T5O A;  4FXG G;  1QO6 A;  2B5I D;  2CG7 A;  2JGW A;  1E88 A;  1MD7 A;  2RKY A;  2W81 A;  3O8E B;  1HCC A;  2ERJ A;  2MCZ A;  1GKN A;  2CKU A;  5FO8 C;  1CKL A;  2JRA A;  1VVC A;  4YNX A;  4MUC A;  4J38 B;  2EC3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...