3ERBA

The crystal structure of c2b, a fragment of complement component c2 produced during c3-convertase formation
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
195
structure length
188
Chain Sequence
SCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPASRLCKSSGQWQTPKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation
pubmed doi rcsb
molecule keywords Complement C2
total genus 36
structure length 188
sequence length 195
ec nomenclature ec 3.4.21.43: Classical-complement-pathway C3/C5 convertase.
pdb deposition date 2008-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3erbA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3erbA03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3erbA01
1E88A 1GKNA 4CSYA 1H04P 2W81A 3L89M 4C16A 1ZJKA 2MCYA 2XWJI 3R62A 2YBYA 4AYMA 2CKUA 1H03P 5HYTB 1MD8A 2RLPA 1C1ZA 2BZMA 1G4GA 2IZ3A 1OK1A 4F4OC 2KMSA 3EJHA 1HCCA 5I0QB 2XQWC 2W80A 4B2SA 3GXEA 2YRAA 5HZPB 2ERJA 1QUBA 2UWNA 3IU3I 1GPZA 4B2RA 5HYUB 4AYIA 1OK3A 1TPMA 2G7IA 4LOTA 1VVCA 2V8EA 1QGBA 2XRBA 1HFHA 2XWBF 1SS2A 4IGDA 3OP8A 1NWVA 4YNXA 3IX0A 3TVJA 3SW0X 2CG6A 1PPQA 3M7PA 3ZRZA 3T5OA 2RLQA 3INBC 3KZJA 3ZD1A 3MQLA 2B5ID 3O8EB 4KKDA 4MUCA 2CG7A 1OJVA 3ERBA 1H2QP 5JPMG 1GHQB 2XRDA 4LOSA 1ELVA 4DJZA 3GOVA 1OK2A 2O39C 5HYPA 3NFPI 2RKYA 1Q3XA 1O9AA 2EHFA 2KRIA 4J38B 1G4FA 4WJG2 1E8BA 4ONTD 3ZD2A 4K12A 2MCZA 4ZH1D 1FBRA 1U5MA 1OJWA 2LOJA 1TPNA 3OXUD 2RKZA 1HFIA 3RJ3D 4AYEA 1UOTP 1H2PP 2WIIC 1VVDA 1GKGA 2JGWA 4A5WB 1LY2A 1Z92B 5FO8C 4FXGG 4AYDA 1QO6A 1CKLA 2EC3A 2RL0A 3OEDC 1OJYA 1SRZA 2IZ4A 2QY0A 4PZ5A 1TPGA 1OK9A 3KXVA 3CALA 2A55A 1E5GA 2JRAA 2JGXA 1MD7A 4JHSA
chains in the Genus database with same CATH superfamily
1E88A 1GKNA 4CSYA 1H04P 2W81A 3L89M 3ZLEA 4BWCA 1ZJKA 4C16A 2MCYA 2XWJI 3R62A 2YBYA 4AYMA 2CKUA 1H03P 5HYTB 1MD8A 2RLPA 1C1ZA 2BZMA 1G4GA 2IZ3A 1OK1A 3NJAA 2X2ZA 2Y8RA 4F4OC 2KMSA 3EJHA 1HCCA 3K3TA 5I0QB 2XQWC 2W80A 4B2SA 3GXEA 2YRAA 4N7EA 5HZPB 2ERJA 1QUBA 2UWNA 3IU3I 1GPZA 4B2RA 5HYUB 4AYIA 1OK3A 1TPMA 2G7IA 4LOTA 5DN5A 3FGTA 3F6KA 1VVCA 2V8EA 1QGBA 2XRBA 1HFHA 2XWBF 1SS2A 4IGDA 3OP8A 4MSLA 1NWVA 4YNXA 3IX0A 3TVJA 3SW0X 2CG6A 1PPQA 3M7PA 3ZRZA 3T5OA 2RLQA 3INBC 4PO7A 3KZJA 3ZD1A 3MQLA 2B5ID 3O8EB 4KKDA 4MUCA 2CG7A 1OJVA 3ERBA 1H2QP 5JPMG 1GHQB 2XRDA 4LOSA 1ELVA 4DJZA 1RLHA 3GOVA 1OK2A 2I2LA 2O39C 2Y8SA 5HYPA 3NFPI 2RKYA 1Q3XA 1O9AA 2EHFA 2KRIA 4J38B 1G4FA 3WSXA 2ZYCA 1E8BA 4ONTD 4WJG2 3VWOA 3ZD2A 3ZLDA 4K12A 2MCZA 4YIZA 4ZH1D 1FBRA 3CI0J 1U5MA 1OJWA 2LOJA 1TPNA 3OXUD 2RKZA 1HFIA 3RJ3D 4AYEA 2Y8TA 1UOTP 1H2PP 2WIIC 1VVDA 3WSYA 1GKGA 2JGWA 4A5WB 1LY2A 1Z92B 5FO8C 4FXGG 4AYDA 1QO6A 1CKLA 2EC3A 2RL0A 3OEDC 3FGRA 4APLA 1OJYA 1SRZA 2IZ4A 2QY0A 4PZ5A 1TPGA 1OK9A 3KXVA 3CALA 2A55A 5DN4A 1E5GA 2JRAA 2JGXA 1MD7A 4JHSA
chains in the Genus database with same CATH topology
1E88A 1GKNA 4CSYA 1H04P 2W81A 3L89M 4C16A 1ZJKA 2MCYA 2XWJI 3R62A 2YBYA 4AYMA 2CKUA 1H03P 5HYTB 1MD8A 2RLPA 1C1ZA 2BZMA 1G4GA 2IZ3A 1OK1A 4F4OC 2KMSA 3EJHA 1HCCA 5I0QB 2XQWC 2W80A 4B2SA 3GXEA 2YRAA 5HZPB 2ERJA 1QUBA 2UWNA 3IU3I 1GPZA 4B2RA 5HYUB 4AYIA 1OK3A 1TPMA 2G7IA 4LOTA 1VVCA 2V8EA 1QGBA 2XRBA 1HFHA 2XWBF 1SS2A 4IGDA 3OP8A 1NWVA 4YNXA 3IX0A 3TVJA 3SW0X 2CG6A 1PPQA 3M7PA 3ZRZA 3T5OA 2RLQA 3INBC 3KZJA 3ZD1A 3MQLA 2B5ID 3O8EB 4KKDA 4MUCA 2CG7A 1OJVA 3ERBA 1H2QP 5JPMG 1GHQB 2XRDA 4LOSA 1ELVA 4DJZA 3GOVA 1OK2A 2O39C 5HYPA 3NFPI 2RKYA 1Q3XA 1O9AA 2EHFA 2KRIA 4J38B 1G4FA 4WJG2 1E8BA 4ONTD 3ZD2A 4K12A 2MCZA 4ZH1D 1FBRA 1U5MA 1OJWA 2LOJA 1TPNA 3OXUD 2RKZA 1HFIA 3RJ3D 4AYEA 1UOTP 1H2PP 2WIIC 1VVDA 1GKGA 2JGWA 4A5WB 1LY2A 1Z92B 5FO8C 4FXGG 4AYDA 1QO6A 1CKLA 2EC3A 2RL0A 3OEDC 1OJYA 1SRZA 2IZ4A 2QY0A 4PZ5A 1TPGA 1OK9A 3KXVA 3CALA 2A55A 1E5GA 2JRAA 2JGXA 1MD7A 4JHSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E88 A;  1GKN A;  4CSY A;  1H04 P;  2W81 A;  3L89 M;  4C16 A;  1ZJK A;  2MCY A;  2XWJ I;  3R62 A;  2YBY A;  4AYM A;  2CKU A;  1H03 P;  5HYT B;  1MD8 A;  2RLP A;  1C1Z A;  2BZM A;  1G4G A;  2IZ3 A;  1OK1 A;  4F4O C;  2KMS A;  3EJH A;  1HCC A;  5I0Q B;  2XQW C;  2W80 A;  4B2S A;  3GXE A;  2YRA A;  5HZP B;  2ERJ A;  1QUB A;  2UWN A;  3IU3 I;  1GPZ A;  4B2R A;  5HYU B;  4AYI A;  1OK3 A;  1TPM A;  2G7I A;  4LOT A;  1VVC A;  2V8E A;  1QGB A;  2XRB A;  1HFH A;  2XWB F;  1SS2 A;  4IGD A;  3OP8 A;  1NWV A;  4YNX A;  3IX0 A;  3TVJ A;  3SW0 X;  2CG6 A;  1PPQ A;  3M7P A;  3ZRZ A;  3T5O A;  2RLQ A;  3INB C;  3KZJ A;  3ZD1 A;  3MQL A;  2B5I D;  3O8E B;  4KKD A;  4MUC A;  2CG7 A;  1OJV A;  3ERB A;  1H2Q P;  5JPM G;  1GHQ B;  2XRD A;  4LOS A;  1ELV A;  4DJZ A;  3GOV A;  1OK2 A;  2O39 C;  5HYP A;  3NFP I;  2RKY A;  1Q3X A;  1O9A A;  2EHF A;  2KRI A;  4J38 B;  1G4F A;  4WJG 2;  1E8B A;  4ONT D;  3ZD2 A;  4K12 A;  2MCZ A;  4ZH1 D;  1FBR A;  1U5M A;  1OJW A;  2LOJ A;  1TPN A;  3OXU D;  2RKZ A;  1HFI A;  3RJ3 D;  4AYE A;  1UOT P;  1H2P P;  2WII C;  1VVD A;  1GKG A;  2JGW A;  4A5W B;  1LY2 A;  1Z92 B;  5FO8 C;  4FXG G;  4AYD A;  1QO6 A;  1CKL A;  2EC3 A;  2RL0 A;  3OED C;  1OJY A;  1SRZ A;  2IZ4 A;  2QY0 A;  4PZ5 A;  1TPG A;  1OK9 A;  3KXV A;  3CAL A;  2A55 A;  1E5G A;  2JRA A;  2JGX A;  1MD7 A;  4JHS A; 
#chains in the Genus database with same CATH topology
 1E88 A;  1GKN A;  4CSY A;  1H04 P;  2W81 A;  3L89 M;  3ZLE A;  4BWC A;  1ZJK A;  4C16 A;  2MCY A;  2XWJ I;  3R62 A;  2YBY A;  4AYM A;  2CKU A;  1H03 P;  5HYT B;  1MD8 A;  2RLP A;  1C1Z A;  2BZM A;  1G4G A;  2IZ3 A;  1OK1 A;  3NJA A;  2X2Z A;  2Y8R A;  4F4O C;  2KMS A;  3EJH A;  1HCC A;  3K3T A;  5I0Q B;  2XQW C;  2W80 A;  4B2S A;  3GXE A;  2YRA A;  4N7E A;  5HZP B;  2ERJ A;  1QUB A;  2UWN A;  3IU3 I;  1GPZ A;  4B2R A;  5HYU B;  4AYI A;  1OK3 A;  1TPM A;  2G7I A;  4LOT A;  5DN5 A;  3FGT A;  3F6K A;  1VVC A;  2V8E A;  1QGB A;  2XRB A;  1HFH A;  2XWB F;  1SS2 A;  4IGD A;  3OP8 A;  4MSL A;  1NWV A;  4YNX A;  3IX0 A;  3TVJ A;  3SW0 X;  2CG6 A;  1PPQ A;  3M7P A;  3ZRZ A;  3T5O A;  2RLQ A;  3INB C;  4PO7 A;  3KZJ A;  3ZD1 A;  3MQL A;  2B5I D;  3O8E B;  4KKD A;  4MUC A;  2CG7 A;  1OJV A;  3ERB A;  1H2Q P;  5JPM G;  1GHQ B;  2XRD A;  4LOS A;  1ELV A;  4DJZ A;  1RLH A;  3GOV A;  1OK2 A;  2I2L A;  2O39 C;  2Y8S A;  5HYP A;  3NFP I;  2RKY A;  1Q3X A;  1O9A A;  2EHF A;  2KRI A;  4J38 B;  1G4F A;  3WSX A;  2ZYC A;  1E8B A;  4ONT D;  4WJG 2;  3VWO A;  3ZD2 A;  3ZLD A;  4K12 A;  2MCZ A;  4YIZ A;  4ZH1 D;  1FBR A;  3CI0 J;  1U5M A;  1OJW A;  2LOJ A;  1TPN A;  3OXU D;  2RKZ A;  1HFI A;  3RJ3 D;  4AYE A;  2Y8T A;  1UOT P;  1H2P P;  2WII C;  1VVD A;  3WSY A;  1GKG A;  2JGW A;  4A5W B;  1LY2 A;  1Z92 B;  5FO8 C;  4FXG G;  4AYD A;  1QO6 A;  1CKL A;  2EC3 A;  2RL0 A;  3OED C;  3FGR A;  4APL A;  1OJY A;  1SRZ A;  2IZ4 A;  2QY0 A;  4PZ5 A;  1TPG A;  1OK9 A;  3KXV A;  3CAL A;  2A55 A;  5DN4 A;  1E5G A;  2JRA A;  2JGX A;  1MD7 A;  4JHS A; 
#chains in the Genus database with same CATH homology
 1E88 A;  1GKN A;  4CSY A;  1H04 P;  2W81 A;  3L89 M;  4C16 A;  1ZJK A;  2MCY A;  2XWJ I;  3R62 A;  2YBY A;  4AYM A;  2CKU A;  1H03 P;  5HYT B;  1MD8 A;  2RLP A;  1C1Z A;  2BZM A;  1G4G A;  2IZ3 A;  1OK1 A;  4F4O C;  2KMS A;  3EJH A;  1HCC A;  5I0Q B;  2XQW C;  2W80 A;  4B2S A;  3GXE A;  2YRA A;  5HZP B;  2ERJ A;  1QUB A;  2UWN A;  3IU3 I;  1GPZ A;  4B2R A;  5HYU B;  4AYI A;  1OK3 A;  1TPM A;  2G7I A;  4LOT A;  1VVC A;  2V8E A;  1QGB A;  2XRB A;  1HFH A;  2XWB F;  1SS2 A;  4IGD A;  3OP8 A;  1NWV A;  4YNX A;  3IX0 A;  3TVJ A;  3SW0 X;  2CG6 A;  1PPQ A;  3M7P A;  3ZRZ A;  3T5O A;  2RLQ A;  3INB C;  3KZJ A;  3ZD1 A;  3MQL A;  2B5I D;  3O8E B;  4KKD A;  4MUC A;  2CG7 A;  1OJV A;  3ERB A;  1H2Q P;  5JPM G;  1GHQ B;  2XRD A;  4LOS A;  1ELV A;  4DJZ A;  3GOV A;  1OK2 A;  2O39 C;  5HYP A;  3NFP I;  2RKY A;  1Q3X A;  1O9A A;  2EHF A;  2KRI A;  4J38 B;  1G4F A;  4WJG 2;  1E8B A;  4ONT D;  3ZD2 A;  4K12 A;  2MCZ A;  4ZH1 D;  1FBR A;  1U5M A;  1OJW A;  2LOJ A;  1TPN A;  3OXU D;  2RKZ A;  1HFI A;  3RJ3 D;  4AYE A;  1UOT P;  1H2P P;  2WII C;  1VVD A;  1GKG A;  2JGW A;  4A5W B;  1LY2 A;  1Z92 B;  5FO8 C;  4FXG G;  4AYD A;  1QO6 A;  1CKL A;  2EC3 A;  2RL0 A;  3OED C;  1OJY A;  1SRZ A;  2IZ4 A;  2QY0 A;  4PZ5 A;  1TPG A;  1OK9 A;  3KXV A;  3CAL A;  2A55 A;  1E5G A;  2JRA A;  2JGX A;  1MD7 A;  4JHS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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