3OP8A

Crystal structure of the domain v from beta2-glycoprotein i
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
85
structure length
85
Chain Sequence
GSCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A Novel Dimeric Inhibitor Targeting Beta2GPI in Beta2GPI/Antibody Complexes Implicated in Antiphospholipid Syndrome.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Beta-2-glycoprotein 1
total genus 13
structure length 85
sequence length 85
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-08-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3op8A00
1O9AA 1HCCA 5HYUB 2G7IA 2CG6A 4K12A 1H03P 1G4GA 2W80A 1H04P 1QO6A 1SRZA 1OK1A 1UOTP 4C16A 4DJZA 2YBYA 2RKZA 2XWJI 3EJHA 1H2PP 3ZD1A 3GXEA 3OP8A 2IZ4A 2XRDA 5HYPA 1E88A 1FBRA 1H2QP 2V8EA 4AYMA 1GHQB 1GKNA 2BZMA 4B2RA 2WIIC 1E5GA 2JGWA 3R62A 4PZ5A 3INBC 2A55A 3IX0A 1VVDA 2B5ID 4MUCA 3KZJA 1QUBA 4ZH1D 1U5MA 1G4FA 1QGBA 2XRBA 4A5WB 1TPMA 2CG7A 3ZD2A 2KMSA 1GPZA 2MCYA 1ELVA 1HFIA 1PPQA 2EHFA 2JRAA 2O39C 5JPMG 2MCZA 1OJWA 1LY2A 1E8BA 1VVCA 3ZRZA 1OJVA 1OK3A 5HZPB 1C1ZA 2W81A 1MD7A 4KKDA 4ONTD 5I0QB 3OEDC 2XWBF 4B2SA 1OK2A 2RLQA 1Q3XA 4J38B 3NFPI 2KRIA 2QY0A 4CSYA 1GKGA 4AYEA 3T5OA 3OXUD 4FXGG 4LOTA 1TPNA 3CALA 2RL0A 3KXVA 1CKLA 1MD8A 1Z92B 2JGXA 3TVJA 2RLPA 4F4OC 3SW0X 2LOJA 5HYTB 2YRAA 4AYDA 2UWNA 4AYIA 3MQLA 4YNXA 1HFHA 4JHSA 3GOVA 2RKYA 3IU3I 2XQWC 2CKUA 1ZJKA 4IGDA 4WJG2 1TPGA 2ERJA 2IZ3A 5FO8C 3L89M 3M7PA 3O8EB 3RJ3D 1NWVA 3ERBA 2EC3A 1SS2A 1OK9A 1OJYA 4LOSA
chains in the Genus database with same CATH superfamily
3CI0J 1O9AA 1HCCA 5HYUB 2G7IA 2CG6A 4K12A 1H03P 1G4GA 2W80A 1H04P 3NJAA 1QO6A 1SRZA 1OK1A 1UOTP 4C16A 4DJZA 2YBYA 2RKZA 2XWJI 3EJHA 1H2PP 3ZD1A 3GXEA 5DN4A 3OP8A 2IZ4A 2XRDA 2ZYCA 2Y8TA 5HYPA 1E88A 1FBRA 1H2QP 2V8EA 4YIZA 1GHQB 4AYMA 1GKNA 2BZMA 4B2RA 2WIIC 3K3TA 1E5GA 2JGWA 3R62A 4PZ5A 3INBC 2A55A 2Y8RA 3IX0A 1VVDA 2B5ID 4MUCA 5DN5A 3KZJA 1QUBA 4ZH1D 1U5MA 1G4FA 1QGBA 2XRBA 4A5WB 1TPMA 2CG7A 2Y8SA 3FGTA 2KMSA 3ZD2A 1GPZA 2MCYA 1ELVA 1HFIA 1PPQA 2EHFA 2JRAA 4APLA 2O39C 5JPMG 2MCZA 1RLHA 1OJWA 1LY2A 3WSYA 1E8BA 1VVCA 3ZRZA 1OJVA 1OK3A 5HZPB 1C1ZA 2X2ZA 2W81A 1MD7A 4KKDA 4ONTD 5I0QB 3FGRA 3OEDC 2XWBF 4B2SA 1OK2A 2RLQA 1Q3XA 4J38B 3NFPI 2KRIA 3ZLEA 2QY0A 4CSYA 1GKGA 4AYEA 3T5OA 3OXUD 4FXGG 4LOTA 1TPNA 3CALA 2RL0A 3WSXA 3ZLDA 3KXVA 1CKLA 1MD8A 1Z92B 2JGXA 3TVJA 2RLPA 4F4OC 3SW0X 2LOJA 5HYTB 2YRAA 4AYDA 2UWNA 4AYIA 2I2LA 3MQLA 4N7EA 4YNXA 1HFHA 4JHSA 3GOVA 2RKYA 3IU3I 4PO7A 2XQWC 2CKUA 1ZJKA 4IGDA 4WJG2 3VWOA 1TPGA 2ERJA 2IZ3A 5FO8C 3F6KA 3L89M 3M7PA 3O8EB 4MSLA 1NWVA 3RJ3D 3ERBA 2EC3A 4BWCA 1SS2A 1OK9A 1OJYA 4LOSA
chains in the Genus database with same CATH topology
1O9AA 1HCCA 5HYUB 2G7IA 2CG6A 4K12A 1H03P 1G4GA 2W80A 1H04P 1QO6A 1SRZA 1OK1A 1UOTP 4C16A 4DJZA 2YBYA 2RKZA 2XWJI 3EJHA 1H2PP 3ZD1A 3GXEA 3OP8A 2IZ4A 2XRDA 5HYPA 1E88A 1FBRA 1H2QP 2V8EA 4AYMA 1GHQB 1GKNA 2BZMA 4B2RA 2WIIC 1E5GA 2JGWA 3R62A 4PZ5A 3INBC 2A55A 3IX0A 1VVDA 2B5ID 4MUCA 3KZJA 1QUBA 4ZH1D 1U5MA 1G4FA 1QGBA 2XRBA 4A5WB 1TPMA 2CG7A 3ZD2A 2KMSA 1GPZA 2MCYA 1ELVA 1HFIA 1PPQA 2EHFA 2JRAA 2O39C 5JPMG 2MCZA 1OJWA 1LY2A 1E8BA 1VVCA 3ZRZA 1OJVA 1OK3A 5HZPB 1C1ZA 2W81A 1MD7A 4KKDA 4ONTD 5I0QB 3OEDC 2XWBF 4B2SA 1OK2A 2RLQA 1Q3XA 4J38B 3NFPI 2KRIA 2QY0A 4CSYA 1GKGA 4AYEA 3T5OA 3OXUD 4FXGG 4LOTA 1TPNA 3CALA 2RL0A 3KXVA 1CKLA 1MD8A 1Z92B 2JGXA 3TVJA 2RLPA 4F4OC 3SW0X 2LOJA 5HYTB 2YRAA 4AYDA 2UWNA 4AYIA 3MQLA 4YNXA 1HFHA 4JHSA 3GOVA 2RKYA 3IU3I 2XQWC 2CKUA 1ZJKA 4IGDA 4WJG2 1TPGA 2ERJA 2IZ3A 5FO8C 3L89M 3M7PA 3O8EB 3RJ3D 1NWVA 3ERBA 2EC3A 1SS2A 1OK9A 1OJYA 4LOSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O9A A;  1HCC A;  5HYU B;  2G7I A;  2CG6 A;  4K12 A;  1H03 P;  1G4G A;  2W80 A;  1H04 P;  1QO6 A;  1SRZ A;  1OK1 A;  1UOT P;  4C16 A;  4DJZ A;  2YBY A;  2RKZ A;  2XWJ I;  3EJH A;  1H2P P;  3ZD1 A;  3GXE A;  3OP8 A;  2IZ4 A;  2XRD A;  5HYP A;  1E88 A;  1FBR A;  1H2Q P;  2V8E A;  4AYM A;  1GHQ B;  1GKN A;  2BZM A;  4B2R A;  2WII C;  1E5G A;  2JGW A;  3R62 A;  4PZ5 A;  3INB C;  2A55 A;  3IX0 A;  1VVD A;  2B5I D;  4MUC A;  3KZJ A;  1QUB A;  4ZH1 D;  1U5M A;  1G4F A;  1QGB A;  2XRB A;  4A5W B;  1TPM A;  2CG7 A;  3ZD2 A;  2KMS A;  1GPZ A;  2MCY A;  1ELV A;  1HFI A;  1PPQ A;  2EHF A;  2JRA A;  2O39 C;  5JPM G;  2MCZ A;  1OJW A;  1LY2 A;  1E8B A;  1VVC A;  3ZRZ A;  1OJV A;  1OK3 A;  5HZP B;  1C1Z A;  2W81 A;  1MD7 A;  4KKD A;  4ONT D;  5I0Q B;  3OED C;  2XWB F;  4B2S A;  1OK2 A;  2RLQ A;  1Q3X A;  4J38 B;  3NFP I;  2KRI A;  2QY0 A;  4CSY A;  1GKG A;  4AYE A;  3T5O A;  3OXU D;  4FXG G;  4LOT A;  1TPN A;  3CAL A;  2RL0 A;  3KXV A;  1CKL A;  1MD8 A;  1Z92 B;  2JGX A;  3TVJ A;  2RLP A;  4F4O C;  3SW0 X;  2LOJ A;  5HYT B;  2YRA A;  4AYD A;  2UWN A;  4AYI A;  3MQL A;  4YNX A;  1HFH A;  4JHS A;  3GOV A;  2RKY A;  3IU3 I;  2XQW C;  2CKU A;  1ZJK A;  4IGD A;  4WJG 2;  1TPG A;  2ERJ A;  2IZ3 A;  5FO8 C;  3L89 M;  3M7P A;  3O8E B;  3RJ3 D;  1NWV A;  3ERB A;  2EC3 A;  1SS2 A;  1OK9 A;  1OJY A;  4LOS A; 
#chains in the Genus database with same CATH topology
 3CI0 J;  1O9A A;  1HCC A;  5HYU B;  2G7I A;  2CG6 A;  4K12 A;  1H03 P;  1G4G A;  2W80 A;  1H04 P;  3NJA A;  1QO6 A;  1SRZ A;  1OK1 A;  1UOT P;  4C16 A;  4DJZ A;  2YBY A;  2RKZ A;  2XWJ I;  3EJH A;  1H2P P;  3ZD1 A;  3GXE A;  5DN4 A;  3OP8 A;  2IZ4 A;  2XRD A;  2ZYC A;  2Y8T A;  5HYP A;  1E88 A;  1FBR A;  1H2Q P;  2V8E A;  4YIZ A;  1GHQ B;  4AYM A;  1GKN A;  2BZM A;  4B2R A;  2WII C;  3K3T A;  1E5G A;  2JGW A;  3R62 A;  4PZ5 A;  3INB C;  2A55 A;  2Y8R A;  3IX0 A;  1VVD A;  2B5I D;  4MUC A;  5DN5 A;  3KZJ A;  1QUB A;  4ZH1 D;  1U5M A;  1G4F A;  1QGB A;  2XRB A;  4A5W B;  1TPM A;  2CG7 A;  2Y8S A;  3FGT A;  2KMS A;  3ZD2 A;  1GPZ A;  2MCY A;  1ELV A;  1HFI A;  1PPQ A;  2EHF A;  2JRA A;  4APL A;  2O39 C;  5JPM G;  2MCZ A;  1RLH A;  1OJW A;  1LY2 A;  3WSY A;  1E8B A;  1VVC A;  3ZRZ A;  1OJV A;  1OK3 A;  5HZP B;  1C1Z A;  2X2Z A;  2W81 A;  1MD7 A;  4KKD A;  4ONT D;  5I0Q B;  3FGR A;  3OED C;  2XWB F;  4B2S A;  1OK2 A;  2RLQ A;  1Q3X A;  4J38 B;  3NFP I;  2KRI A;  3ZLE A;  2QY0 A;  4CSY A;  1GKG A;  4AYE A;  3T5O A;  3OXU D;  4FXG G;  4LOT A;  1TPN A;  3CAL A;  2RL0 A;  3WSX A;  3ZLD A;  3KXV A;  1CKL A;  1MD8 A;  1Z92 B;  2JGX A;  3TVJ A;  2RLP A;  4F4O C;  3SW0 X;  2LOJ A;  5HYT B;  2YRA A;  4AYD A;  2UWN A;  4AYI A;  2I2L A;  3MQL A;  4N7E A;  4YNX A;  1HFH A;  4JHS A;  3GOV A;  2RKY A;  3IU3 I;  4PO7 A;  2XQW C;  2CKU A;  1ZJK A;  4IGD A;  4WJG 2;  3VWO A;  1TPG A;  2ERJ A;  2IZ3 A;  5FO8 C;  3F6K A;  3L89 M;  3M7P A;  3O8E B;  4MSL A;  1NWV A;  3RJ3 D;  3ERB A;  2EC3 A;  4BWC A;  1SS2 A;  1OK9 A;  1OJY A;  4LOS A; 
#chains in the Genus database with same CATH homology
 1O9A A;  1HCC A;  5HYU B;  2G7I A;  2CG6 A;  4K12 A;  1H03 P;  1G4G A;  2W80 A;  1H04 P;  1QO6 A;  1SRZ A;  1OK1 A;  1UOT P;  4C16 A;  4DJZ A;  2YBY A;  2RKZ A;  2XWJ I;  3EJH A;  1H2P P;  3ZD1 A;  3GXE A;  3OP8 A;  2IZ4 A;  2XRD A;  5HYP A;  1E88 A;  1FBR A;  1H2Q P;  2V8E A;  4AYM A;  1GHQ B;  1GKN A;  2BZM A;  4B2R A;  2WII C;  1E5G A;  2JGW A;  3R62 A;  4PZ5 A;  3INB C;  2A55 A;  3IX0 A;  1VVD A;  2B5I D;  4MUC A;  3KZJ A;  1QUB A;  4ZH1 D;  1U5M A;  1G4F A;  1QGB A;  2XRB A;  4A5W B;  1TPM A;  2CG7 A;  3ZD2 A;  2KMS A;  1GPZ A;  2MCY A;  1ELV A;  1HFI A;  1PPQ A;  2EHF A;  2JRA A;  2O39 C;  5JPM G;  2MCZ A;  1OJW A;  1LY2 A;  1E8B A;  1VVC A;  3ZRZ A;  1OJV A;  1OK3 A;  5HZP B;  1C1Z A;  2W81 A;  1MD7 A;  4KKD A;  4ONT D;  5I0Q B;  3OED C;  2XWB F;  4B2S A;  1OK2 A;  2RLQ A;  1Q3X A;  4J38 B;  3NFP I;  2KRI A;  2QY0 A;  4CSY A;  1GKG A;  4AYE A;  3T5O A;  3OXU D;  4FXG G;  4LOT A;  1TPN A;  3CAL A;  2RL0 A;  3KXV A;  1CKL A;  1MD8 A;  1Z92 B;  2JGX A;  3TVJ A;  2RLP A;  4F4O C;  3SW0 X;  2LOJ A;  5HYT B;  2YRA A;  4AYD A;  2UWN A;  4AYI A;  3MQL A;  4YNX A;  1HFH A;  4JHS A;  3GOV A;  2RKY A;  3IU3 I;  2XQW C;  2CKU A;  1ZJK A;  4IGD A;  4WJG 2;  1TPG A;  2ERJ A;  2IZ3 A;  5FO8 C;  3L89 M;  3M7P A;  3O8E B;  3RJ3 D;  1NWV A;  3ERB A;  2EC3 A;  1SS2 A;  1OK9 A;  1OJY A;  4LOS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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