3OXUD

Complement components factor h ccp19-20 and c3d in complex
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
125
structure length
125
Chain Sequence
GKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for engagement by complement factor H of C3b on a self surface.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Complement C3
total genus 24
structure length 125
sequence length 125
chains with identical sequence E, F
ec nomenclature
pdb deposition date 2010-09-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3oxuD01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3oxuD02
1HFIA 2LOJA 2G7IA 2XQWC 4WJG2 3M7PA 3T5OA 3INBC 1H04P 3GOVA 1Q3XA 3OXUD 1HFHA 2XRDA 2QY0A 4ZH1D 2JRAA 3MQLA 3L89M 3ZRZA 2ERJA 3ZD1A 1GKGA 1MD7A 2UWNA 2KRIA 2RLPA 4B2SA 1UOTP 2JGXA 2IZ3A 1QGBA 1QO6A 1O9AA 1U5MA 3KZJA 4AYMA 1VVCA 1E88A 2XWBF 1CKLA 4ONTD 2W80A 2IZ4A 2YBYA 1TPMA 1OK9A 2KMSA 5HYUB 4LOSA 3TVJA 5I0QB 4K12A 2V8EA 3NFPI 2MCYA 1H03P 1OK2A 2RKZA 1OJWA 1E5GA 1GKNA 2RKYA 4AYIA 1PPQA 2XRBA 5FO8C 4J38B 4AYEA 1OJVA 3GXEA 3RJ3D 4F4OC 1H2QP 2JGWA 4MUCA 4PZ5A 4JHSA 3KXVA 1SS2A 2YRAA 4DJZA 1GPZA 3IU3I 4CSYA 4LOTA 2CKUA 4YNXA 1GHQB 4KKDA 4IGDA 4B2RA 2RL0A 3CALA 4AYDA 1FBRA 1QUBA 4C16A 4FXGG 2A55A 1H2PP 1SRZA 1ELVA 2BZMA 2W81A 1HCCA 1G4FA 1C1ZA 3EJHA 2O39C 2EHFA 1TPNA 1LY2A 1Z92B 3SW0X 1MD8A 1TPGA 3O8EB 2WIIC 1OJYA 1OK3A 3ZD2A 2MCZA 3ERBA 5JPMG 1ZJKA 1NWVA 5HYTB 1G4GA 2XWJI 3OEDC 3OP8A 2B5ID 2RLQA 2CG6A 2CG7A 3IX0A 1OK1A 3R62A 2EC3A 5HYPA 5HZPB 1E8BA 1VVDA 4A5WB
chains in the Genus database with same CATH superfamily
1HFIA 2LOJA 2G7IA 2XQWC 4WJG2 3M7PA 3T5OA 3INBC 1H04P 3GOVA 1Q3XA 3CI0J 3OXUD 3K3TA 1HFHA 2XRDA 2QY0A 4ZH1D 2JRAA 3MQLA 3L89M 3ZRZA 2ERJA 3ZD1A 1GKGA 1MD7A 2UWNA 5DN4A 2KRIA 2RLPA 3FGTA 4B2SA 2Y8RA 1UOTP 2JGXA 2IZ3A 1QGBA 1QO6A 1O9AA 1U5MA 3F6KA 3KZJA 4PO7A 4AYMA 1VVCA 1E88A 2XWBF 1CKLA 4ONTD 2W80A 4MSLA 2IZ4A 2YBYA 3NJAA 1TPMA 1OK9A 2KMSA 5HYUB 4LOSA 3TVJA 2ZYCA 5I0QB 4K12A 4APLA 3FGRA 2V8EA 3NFPI 2MCYA 1H03P 1OK2A 2RKZA 1OJWA 1E5GA 1GKNA 2RKYA 4AYIA 1PPQA 2XRBA 5FO8C 4J38B 4AYEA 1OJVA 3GXEA 3RJ3D 4F4OC 1H2QP 2JGWA 3VWOA 4MUCA 4PZ5A 4JHSA 3KXVA 1SS2A 2YRAA 4BWCA 4DJZA 1GPZA 3IU3I 4CSYA 4LOTA 2CKUA 4YNXA 1GHQB 4KKDA 4IGDA 4B2RA 2RL0A 3CALA 4AYDA 1FBRA 1QUBA 4C16A 4FXGG 2Y8TA 2A55A 1H2PP 1SRZA 1ELVA 2BZMA 4N7EA 2W81A 1HCCA 3ZLDA 1G4FA 1C1ZA 2I2LA 3EJHA 2O39C 3WSYA 2EHFA 1TPNA 1LY2A 1Z92B 3SW0X 1MD8A 1TPGA 5DN5A 3O8EB 2WIIC 3ZLEA 1OJYA 1OK3A 3ZD2A 2MCZA 3ERBA 5JPMG 1ZJKA 1NWVA 5HYTB 1G4GA 2XWJI 2Y8SA 2X2ZA 3OEDC 3OP8A 1RLHA 2B5ID 2RLQA 2CG6A 2CG7A 3IX0A 4YIZA 3WSXA 1OK1A 3R62A 2EC3A 5HYPA 5HZPB 1E8BA 1VVDA 4A5WB
chains in the Genus database with same CATH topology
1HFIA 2LOJA 2G7IA 2XQWC 4WJG2 3M7PA 3T5OA 3INBC 1H04P 3GOVA 1Q3XA 3OXUD 1HFHA 2XRDA 2QY0A 4ZH1D 2JRAA 3MQLA 3L89M 3ZRZA 2ERJA 3ZD1A 1GKGA 1MD7A 2UWNA 2KRIA 2RLPA 4B2SA 1UOTP 2JGXA 2IZ3A 1QGBA 1QO6A 1O9AA 1U5MA 3KZJA 4AYMA 1VVCA 1E88A 2XWBF 1CKLA 4ONTD 2W80A 2IZ4A 2YBYA 1TPMA 1OK9A 2KMSA 5HYUB 4LOSA 3TVJA 5I0QB 4K12A 2V8EA 3NFPI 2MCYA 1H03P 1OK2A 2RKZA 1OJWA 1E5GA 1GKNA 2RKYA 4AYIA 1PPQA 2XRBA 5FO8C 4J38B 4AYEA 1OJVA 3GXEA 3RJ3D 4F4OC 1H2QP 2JGWA 4MUCA 4PZ5A 4JHSA 3KXVA 1SS2A 2YRAA 4DJZA 1GPZA 3IU3I 4CSYA 4LOTA 2CKUA 4YNXA 1GHQB 4KKDA 4IGDA 4B2RA 2RL0A 3CALA 4AYDA 1FBRA 1QUBA 4C16A 4FXGG 2A55A 1H2PP 1SRZA 1ELVA 2BZMA 2W81A 1HCCA 1G4FA 1C1ZA 3EJHA 2O39C 2EHFA 1TPNA 1LY2A 1Z92B 3SW0X 1MD8A 1TPGA 3O8EB 2WIIC 1OJYA 1OK3A 3ZD2A 2MCZA 3ERBA 5JPMG 1ZJKA 1NWVA 5HYTB 1G4GA 2XWJI 3OEDC 3OP8A 2B5ID 2RLQA 2CG6A 2CG7A 3IX0A 1OK1A 3R62A 2EC3A 5HYPA 5HZPB 1E8BA 1VVDA 4A5WB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HFI A;  2LOJ A;  2G7I A;  2XQW C;  4WJG 2;  3M7P A;  3T5O A;  3INB C;  1H04 P;  3GOV A;  1Q3X A;  3OXU D;  1HFH A;  2XRD A;  2QY0 A;  4ZH1 D;  2JRA A;  3MQL A;  3L89 M;  3ZRZ A;  2ERJ A;  3ZD1 A;  1GKG A;  1MD7 A;  2UWN A;  2KRI A;  2RLP A;  4B2S A;  1UOT P;  2JGX A;  2IZ3 A;  1QGB A;  1QO6 A;  1O9A A;  1U5M A;  3KZJ A;  4AYM A;  1VVC A;  1E88 A;  2XWB F;  1CKL A;  4ONT D;  2W80 A;  2IZ4 A;  2YBY A;  1TPM A;  1OK9 A;  2KMS A;  5HYU B;  4LOS A;  3TVJ A;  5I0Q B;  4K12 A;  2V8E A;  3NFP I;  2MCY A;  1H03 P;  1OK2 A;  2RKZ A;  1OJW A;  1E5G A;  1GKN A;  2RKY A;  4AYI A;  1PPQ A;  2XRB A;  5FO8 C;  4J38 B;  4AYE A;  1OJV A;  3GXE A;  3RJ3 D;  4F4O C;  1H2Q P;  2JGW A;  4MUC A;  4PZ5 A;  4JHS A;  3KXV A;  1SS2 A;  2YRA A;  4DJZ A;  1GPZ A;  3IU3 I;  4CSY A;  4LOT A;  2CKU A;  4YNX A;  1GHQ B;  4KKD A;  4IGD A;  4B2R A;  2RL0 A;  3CAL A;  4AYD A;  1FBR A;  1QUB A;  4C16 A;  4FXG G;  2A55 A;  1H2P P;  1SRZ A;  1ELV A;  2BZM A;  2W81 A;  1HCC A;  1G4F A;  1C1Z A;  3EJH A;  2O39 C;  2EHF A;  1TPN A;  1LY2 A;  1Z92 B;  3SW0 X;  1MD8 A;  1TPG A;  3O8E B;  2WII C;  1OJY A;  1OK3 A;  3ZD2 A;  2MCZ A;  3ERB A;  5JPM G;  1ZJK A;  1NWV A;  5HYT B;  1G4G A;  2XWJ I;  3OED C;  3OP8 A;  2B5I D;  2RLQ A;  2CG6 A;  2CG7 A;  3IX0 A;  1OK1 A;  3R62 A;  2EC3 A;  5HYP A;  5HZP B;  1E8B A;  1VVD A;  4A5W B; 
#chains in the Genus database with same CATH topology
 1HFI A;  2LOJ A;  2G7I A;  2XQW C;  4WJG 2;  3M7P A;  3T5O A;  3INB C;  1H04 P;  3GOV A;  1Q3X A;  3CI0 J;  3OXU D;  3K3T A;  1HFH A;  2XRD A;  2QY0 A;  4ZH1 D;  2JRA A;  3MQL A;  3L89 M;  3ZRZ A;  2ERJ A;  3ZD1 A;  1GKG A;  1MD7 A;  2UWN A;  5DN4 A;  2KRI A;  2RLP A;  3FGT A;  4B2S A;  2Y8R A;  1UOT P;  2JGX A;  2IZ3 A;  1QGB A;  1QO6 A;  1O9A A;  1U5M A;  3F6K A;  3KZJ A;  4PO7 A;  4AYM A;  1VVC A;  1E88 A;  2XWB F;  1CKL A;  4ONT D;  2W80 A;  4MSL A;  2IZ4 A;  2YBY A;  3NJA A;  1TPM A;  1OK9 A;  2KMS A;  5HYU B;  4LOS A;  3TVJ A;  2ZYC A;  5I0Q B;  4K12 A;  4APL A;  3FGR A;  2V8E A;  3NFP I;  2MCY A;  1H03 P;  1OK2 A;  2RKZ A;  1OJW A;  1E5G A;  1GKN A;  2RKY A;  4AYI A;  1PPQ A;  2XRB A;  5FO8 C;  4J38 B;  4AYE A;  1OJV A;  3GXE A;  3RJ3 D;  4F4O C;  1H2Q P;  2JGW A;  3VWO A;  4MUC A;  4PZ5 A;  4JHS A;  3KXV A;  1SS2 A;  2YRA A;  4BWC A;  4DJZ A;  1GPZ A;  3IU3 I;  4CSY A;  4LOT A;  2CKU A;  4YNX A;  1GHQ B;  4KKD A;  4IGD A;  4B2R A;  2RL0 A;  3CAL A;  4AYD A;  1FBR A;  1QUB A;  4C16 A;  4FXG G;  2Y8T A;  2A55 A;  1H2P P;  1SRZ A;  1ELV A;  2BZM A;  4N7E A;  2W81 A;  1HCC A;  3ZLD A;  1G4F A;  1C1Z A;  2I2L A;  3EJH A;  2O39 C;  3WSY A;  2EHF A;  1TPN A;  1LY2 A;  1Z92 B;  3SW0 X;  1MD8 A;  1TPG A;  5DN5 A;  3O8E B;  2WII C;  3ZLE A;  1OJY A;  1OK3 A;  3ZD2 A;  2MCZ A;  3ERB A;  5JPM G;  1ZJK A;  1NWV A;  5HYT B;  1G4G A;  2XWJ I;  2Y8S A;  2X2Z A;  3OED C;  3OP8 A;  1RLH A;  2B5I D;  2RLQ A;  2CG6 A;  2CG7 A;  3IX0 A;  4YIZ A;  3WSX A;  1OK1 A;  3R62 A;  2EC3 A;  5HYP A;  5HZP B;  1E8B A;  1VVD A;  4A5W B; 
#chains in the Genus database with same CATH homology
 1HFI A;  2LOJ A;  2G7I A;  2XQW C;  4WJG 2;  3M7P A;  3T5O A;  3INB C;  1H04 P;  3GOV A;  1Q3X A;  3OXU D;  1HFH A;  2XRD A;  2QY0 A;  4ZH1 D;  2JRA A;  3MQL A;  3L89 M;  3ZRZ A;  2ERJ A;  3ZD1 A;  1GKG A;  1MD7 A;  2UWN A;  2KRI A;  2RLP A;  4B2S A;  1UOT P;  2JGX A;  2IZ3 A;  1QGB A;  1QO6 A;  1O9A A;  1U5M A;  3KZJ A;  4AYM A;  1VVC A;  1E88 A;  2XWB F;  1CKL A;  4ONT D;  2W80 A;  2IZ4 A;  2YBY A;  1TPM A;  1OK9 A;  2KMS A;  5HYU B;  4LOS A;  3TVJ A;  5I0Q B;  4K12 A;  2V8E A;  3NFP I;  2MCY A;  1H03 P;  1OK2 A;  2RKZ A;  1OJW A;  1E5G A;  1GKN A;  2RKY A;  4AYI A;  1PPQ A;  2XRB A;  5FO8 C;  4J38 B;  4AYE A;  1OJV A;  3GXE A;  3RJ3 D;  4F4O C;  1H2Q P;  2JGW A;  4MUC A;  4PZ5 A;  4JHS A;  3KXV A;  1SS2 A;  2YRA A;  4DJZ A;  1GPZ A;  3IU3 I;  4CSY A;  4LOT A;  2CKU A;  4YNX A;  1GHQ B;  4KKD A;  4IGD A;  4B2R A;  2RL0 A;  3CAL A;  4AYD A;  1FBR A;  1QUB A;  4C16 A;  4FXG G;  2A55 A;  1H2P P;  1SRZ A;  1ELV A;  2BZM A;  2W81 A;  1HCC A;  1G4F A;  1C1Z A;  3EJH A;  2O39 C;  2EHF A;  1TPN A;  1LY2 A;  1Z92 B;  3SW0 X;  1MD8 A;  1TPG A;  3O8E B;  2WII C;  1OJY A;  1OK3 A;  3ZD2 A;  2MCZ A;  3ERB A;  5JPM G;  1ZJK A;  1NWV A;  5HYT B;  1G4G A;  2XWJ I;  3OED C;  3OP8 A;  2B5I D;  2RLQ A;  2CG6 A;  2CG7 A;  3IX0 A;  1OK1 A;  3R62 A;  2EC3 A;  5HYP A;  5HZP B;  1E8B A;  1VVD A;  4A5W B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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