3SW0X

Structure of the c-terminal region (modules 18-20) of complement regulator factor h
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
186
structure length
186
Chain Sequence
GTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH).
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Complement factor H
total genus 34
structure length 186
sequence length 186
ec nomenclature
pdb deposition date 2011-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3sw0X01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3sw0X02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 3sw0X03
2XWJI 3ZD2A 2EHFA 3MQLA 1CKLA 2JGXA 5FO8C 3RJ3D 1GKGA 2A55A 1C1ZA 1G4GA 4B2SA 1E88A 1HFIA 3OP8A 5HYPA 2W80A 2JRAA 1SS2A 3IX0A 1ZJKA 1H2PP 4AYEA 2RLQA 2LOJA 3ZRZA 4A5WB 3R62A 5HZPB 2YBYA 1FBRA 1VVDA 1SRZA 1HCCA 5HYUB 1TPGA 4JHSA 1MD7A 1GKNA 2ERJA 2RKZA 5HYTB 1Z92B 2RL0A 3ERBA 1OJVA 4PZ5A 2CG7A 2O39C 3O8EB 3L89M 2RKYA 1QUBA 1VVCA 1MD8A 4B2RA 1OK9A 4MUCA 1OK2A 4F4OC 2XRDA 1TPMA 4J38B 2BZMA 1HFHA 2XWBF 4LOSA 4K12A 1E8BA 4LOTA 4YNXA 4AYMA 4AYDA 4KKDA 2XQWC 1G4FA 3CALA 1QGBA 3GOVA 2KRIA 3EJHA 4FXGG 3INBC 4WJG2 1H2QP 3NFPI 1OJYA 1U5MA 1OK3A 1H03P 2JGWA 3KZJA 1UOTP 4DJZA 3KXVA 3T5OA 2W81A 2QY0A 2YRAA 2CG6A 2IZ3A 4ONTD 5I0QB 2MCZA 2IZ4A 3TVJA 1NWVA 3SW0X 1Q3XA 1OK1A 1QO6A 5JPMG 2WIIC 1H04P 4CSYA 1LY2A 1TPNA 4IGDA 4C16A 2KMSA 2B5ID 2XRBA 1PPQA 1ELVA 4AYIA 1GHQB 3ZD1A 3OEDC 2UWNA 1GPZA 2EC3A 2V8EA 1E5GA 3M7PA 3OXUD 1O9AA 4ZH1D 2MCYA 1OJWA 3GXEA 2RLPA 2G7IA 3IU3I 2CKUA
chains in the Genus database with same CATH superfamily
2XWJI 3ZD2A 2EHFA 3MQLA 1CKLA 2JGXA 5FO8C 3RJ3D 1GKGA 2A55A 1C1ZA 1G4GA 2Y8RA 4B2SA 1E88A 1HFIA 3OP8A 5HYPA 2W80A 2JRAA 3FGTA 1SS2A 3IX0A 1ZJKA 2Y8SA 1H2PP 4AYEA 2RLQA 2LOJA 3ZRZA 4A5WB 3R62A 5HZPB 2YBYA 1FBRA 1VVDA 1SRZA 1HCCA 4N7EA 5DN4A 1TPGA 5HYUB 4JHSA 1MD7A 1GKNA 2ERJA 2RKZA 5HYTB 1Z92B 2RL0A 3ERBA 1OJVA 4PZ5A 2CG7A 2O39C 3O8EB 3L89M 2RKYA 1QUBA 1VVCA 2ZYCA 1MD8A 4B2RA 1OK9A 4MUCA 1OK2A 4YIZA 4F4OC 1TPMA 2XRDA 4J38B 4PO7A 2BZMA 3ZLEA 1HFHA 2XWBF 4LOSA 4K12A 1E8BA 4LOTA 4YNXA 4AYMA 3F6KA 4AYDA 3NJAA 3FGRA 4KKDA 3VWOA 2XQWC 1G4FA 3CALA 3WSXA 1QGBA 3GOVA 2KRIA 4APLA 3EJHA 4FXGG 3INBC 4WJG2 1H2QP 3NFPI 1OJYA 1U5MA 1OK3A 1H03P 2JGWA 3KZJA 1UOTP 4DJZA 3KXVA 2X2ZA 3T5OA 2W81A 4BWCA 2QY0A 2I2LA 2YRAA 2CG6A 2IZ3A 4ONTD 5I0QB 2MCZA 2IZ4A 3TVJA 1NWVA 3SW0X 1Q3XA 1OK1A 1RLHA 1QO6A 5JPMG 2WIIC 1H04P 4CSYA 1LY2A 1TPNA 4IGDA 4C16A 2KMSA 2B5ID 2XRBA 1PPQA 1ELVA 4AYIA 1GHQB 3ZD1A 3OEDC 2UWNA 1GPZA 2EC3A 3ZLDA 2V8EA 1E5GA 2Y8TA 3M7PA 3K3TA 3OXUD 1O9AA 4MSLA 2MCYA 4ZH1D 3WSYA 1OJWA 3GXEA 5DN5A 3CI0J 2RLPA 2G7IA 3IU3I 2CKUA
chains in the Genus database with same CATH topology
2XWJI 3ZD2A 2EHFA 3MQLA 1CKLA 2JGXA 5FO8C 3RJ3D 1GKGA 2A55A 1C1ZA 1G4GA 4B2SA 1E88A 1HFIA 3OP8A 5HYPA 2W80A 2JRAA 1SS2A 3IX0A 1ZJKA 1H2PP 4AYEA 2RLQA 2LOJA 3ZRZA 4A5WB 3R62A 5HZPB 2YBYA 1FBRA 1VVDA 1SRZA 1HCCA 5HYUB 1TPGA 4JHSA 1MD7A 1GKNA 2ERJA 2RKZA 5HYTB 1Z92B 2RL0A 3ERBA 1OJVA 4PZ5A 2CG7A 2O39C 3O8EB 3L89M 2RKYA 1QUBA 1VVCA 1MD8A 4B2RA 1OK9A 4MUCA 1OK2A 4F4OC 2XRDA 1TPMA 4J38B 2BZMA 1HFHA 2XWBF 4LOSA 4K12A 1E8BA 4LOTA 4YNXA 4AYMA 4AYDA 4KKDA 2XQWC 1G4FA 3CALA 1QGBA 3GOVA 2KRIA 3EJHA 4FXGG 3INBC 4WJG2 1H2QP 3NFPI 1OJYA 1U5MA 1OK3A 1H03P 2JGWA 3KZJA 1UOTP 4DJZA 3KXVA 3T5OA 2W81A 2QY0A 2YRAA 2CG6A 2IZ3A 4ONTD 5I0QB 2MCZA 2IZ4A 3TVJA 1NWVA 3SW0X 1Q3XA 1OK1A 1QO6A 5JPMG 2WIIC 1H04P 4CSYA 1LY2A 1TPNA 4IGDA 4C16A 2KMSA 2B5ID 2XRBA 1PPQA 1ELVA 4AYIA 1GHQB 3ZD1A 3OEDC 2UWNA 1GPZA 2EC3A 2V8EA 1E5GA 3M7PA 3OXUD 1O9AA 4ZH1D 2MCYA 1OJWA 3GXEA 2RLPA 2G7IA 3IU3I 2CKUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XWJ I;  3ZD2 A;  2EHF A;  3MQL A;  1CKL A;  2JGX A;  5FO8 C;  3RJ3 D;  1GKG A;  2A55 A;  1C1Z A;  1G4G A;  4B2S A;  1E88 A;  1HFI A;  3OP8 A;  5HYP A;  2W80 A;  2JRA A;  1SS2 A;  3IX0 A;  1ZJK A;  1H2P P;  4AYE A;  2RLQ A;  2LOJ A;  3ZRZ A;  4A5W B;  3R62 A;  5HZP B;  2YBY A;  1FBR A;  1VVD A;  1SRZ A;  1HCC A;  5HYU B;  1TPG A;  4JHS A;  1MD7 A;  1GKN A;  2ERJ A;  2RKZ A;  5HYT B;  1Z92 B;  2RL0 A;  3ERB A;  1OJV A;  4PZ5 A;  2CG7 A;  2O39 C;  3O8E B;  3L89 M;  2RKY A;  1QUB A;  1VVC A;  1MD8 A;  4B2R A;  1OK9 A;  4MUC A;  1OK2 A;  4F4O C;  2XRD A;  1TPM A;  4J38 B;  2BZM A;  1HFH A;  2XWB F;  4LOS A;  4K12 A;  1E8B A;  4LOT A;  4YNX A;  4AYM A;  4AYD A;  4KKD A;  2XQW C;  1G4F A;  3CAL A;  1QGB A;  3GOV A;  2KRI A;  3EJH A;  4FXG G;  3INB C;  4WJG 2;  1H2Q P;  3NFP I;  1OJY A;  1U5M A;  1OK3 A;  1H03 P;  2JGW A;  3KZJ A;  1UOT P;  4DJZ A;  3KXV A;  3T5O A;  2W81 A;  2QY0 A;  2YRA A;  2CG6 A;  2IZ3 A;  4ONT D;  5I0Q B;  2MCZ A;  2IZ4 A;  3TVJ A;  1NWV A;  3SW0 X;  1Q3X A;  1OK1 A;  1QO6 A;  5JPM G;  2WII C;  1H04 P;  4CSY A;  1LY2 A;  1TPN A;  4IGD A;  4C16 A;  2KMS A;  2B5I D;  2XRB A;  1PPQ A;  1ELV A;  4AYI A;  1GHQ B;  3ZD1 A;  3OED C;  2UWN A;  1GPZ A;  2EC3 A;  2V8E A;  1E5G A;  3M7P A;  3OXU D;  1O9A A;  4ZH1 D;  2MCY A;  1OJW A;  3GXE A;  2RLP A;  2G7I A;  3IU3 I;  2CKU A; 
#chains in the Genus database with same CATH topology
 2XWJ I;  3ZD2 A;  2EHF A;  3MQL A;  1CKL A;  2JGX A;  5FO8 C;  3RJ3 D;  1GKG A;  2A55 A;  1C1Z A;  1G4G A;  2Y8R A;  4B2S A;  1E88 A;  1HFI A;  3OP8 A;  5HYP A;  2W80 A;  2JRA A;  3FGT A;  1SS2 A;  3IX0 A;  1ZJK A;  2Y8S A;  1H2P P;  4AYE A;  2RLQ A;  2LOJ A;  3ZRZ A;  4A5W B;  3R62 A;  5HZP B;  2YBY A;  1FBR A;  1VVD A;  1SRZ A;  1HCC A;  4N7E A;  5DN4 A;  1TPG A;  5HYU B;  4JHS A;  1MD7 A;  1GKN A;  2ERJ A;  2RKZ A;  5HYT B;  1Z92 B;  2RL0 A;  3ERB A;  1OJV A;  4PZ5 A;  2CG7 A;  2O39 C;  3O8E B;  3L89 M;  2RKY A;  1QUB A;  1VVC A;  2ZYC A;  1MD8 A;  4B2R A;  1OK9 A;  4MUC A;  1OK2 A;  4YIZ A;  4F4O C;  1TPM A;  2XRD A;  4J38 B;  4PO7 A;  2BZM A;  3ZLE A;  1HFH A;  2XWB F;  4LOS A;  4K12 A;  1E8B A;  4LOT A;  4YNX A;  4AYM A;  3F6K A;  4AYD A;  3NJA A;  3FGR A;  4KKD A;  3VWO A;  2XQW C;  1G4F A;  3CAL A;  3WSX A;  1QGB A;  3GOV A;  2KRI A;  4APL A;  3EJH A;  4FXG G;  3INB C;  4WJG 2;  1H2Q P;  3NFP I;  1OJY A;  1U5M A;  1OK3 A;  1H03 P;  2JGW A;  3KZJ A;  1UOT P;  4DJZ A;  3KXV A;  2X2Z A;  3T5O A;  2W81 A;  4BWC A;  2QY0 A;  2I2L A;  2YRA A;  2CG6 A;  2IZ3 A;  4ONT D;  5I0Q B;  2MCZ A;  2IZ4 A;  3TVJ A;  1NWV A;  3SW0 X;  1Q3X A;  1OK1 A;  1RLH A;  1QO6 A;  5JPM G;  2WII C;  1H04 P;  4CSY A;  1LY2 A;  1TPN A;  4IGD A;  4C16 A;  2KMS A;  2B5I D;  2XRB A;  1PPQ A;  1ELV A;  4AYI A;  1GHQ B;  3ZD1 A;  3OED C;  2UWN A;  1GPZ A;  2EC3 A;  3ZLD A;  2V8E A;  1E5G A;  2Y8T A;  3M7P A;  3K3T A;  3OXU D;  1O9A A;  4MSL A;  2MCY A;  4ZH1 D;  3WSY A;  1OJW A;  3GXE A;  5DN5 A;  3CI0 J;  2RLP A;  2G7I A;  3IU3 I;  2CKU A; 
#chains in the Genus database with same CATH homology
 2XWJ I;  3ZD2 A;  2EHF A;  3MQL A;  1CKL A;  2JGX A;  5FO8 C;  3RJ3 D;  1GKG A;  2A55 A;  1C1Z A;  1G4G A;  4B2S A;  1E88 A;  1HFI A;  3OP8 A;  5HYP A;  2W80 A;  2JRA A;  1SS2 A;  3IX0 A;  1ZJK A;  1H2P P;  4AYE A;  2RLQ A;  2LOJ A;  3ZRZ A;  4A5W B;  3R62 A;  5HZP B;  2YBY A;  1FBR A;  1VVD A;  1SRZ A;  1HCC A;  5HYU B;  1TPG A;  4JHS A;  1MD7 A;  1GKN A;  2ERJ A;  2RKZ A;  5HYT B;  1Z92 B;  2RL0 A;  3ERB A;  1OJV A;  4PZ5 A;  2CG7 A;  2O39 C;  3O8E B;  3L89 M;  2RKY A;  1QUB A;  1VVC A;  1MD8 A;  4B2R A;  1OK9 A;  4MUC A;  1OK2 A;  4F4O C;  2XRD A;  1TPM A;  4J38 B;  2BZM A;  1HFH A;  2XWB F;  4LOS A;  4K12 A;  1E8B A;  4LOT A;  4YNX A;  4AYM A;  4AYD A;  4KKD A;  2XQW C;  1G4F A;  3CAL A;  1QGB A;  3GOV A;  2KRI A;  3EJH A;  4FXG G;  3INB C;  4WJG 2;  1H2Q P;  3NFP I;  1OJY A;  1U5M A;  1OK3 A;  1H03 P;  2JGW A;  3KZJ A;  1UOT P;  4DJZ A;  3KXV A;  3T5O A;  2W81 A;  2QY0 A;  2YRA A;  2CG6 A;  2IZ3 A;  4ONT D;  5I0Q B;  2MCZ A;  2IZ4 A;  3TVJ A;  1NWV A;  3SW0 X;  1Q3X A;  1OK1 A;  1QO6 A;  5JPM G;  2WII C;  1H04 P;  4CSY A;  1LY2 A;  1TPN A;  4IGD A;  4C16 A;  2KMS A;  2B5I D;  2XRB A;  1PPQ A;  1ELV A;  4AYI A;  1GHQ B;  3ZD1 A;  3OED C;  2UWN A;  1GPZ A;  2EC3 A;  2V8E A;  1E5G A;  3M7P A;  3OXU D;  1O9A A;  4ZH1 D;  2MCY A;  1OJW A;  3GXE A;  2RLP A;  2G7I A;  3IU3 I;  2CKU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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