4ONTD

Ternary host recognition complex of complement factor h, c3d, and sialic acid
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
126
structure length
126
Chain Sequence
FGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCRNGQWSEPPKCLHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRLSSRSHTLRTTCWDGKLEYPTCAKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for sialic acid-mediated self-recognition by complement factor H.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords Complement factor H
total genus 22
structure length 126
sequence length 126
chains with identical sequence E, F
ec nomenclature
pdb deposition date 2014-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 4ontD01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 4ontD02
3T5OA 2UWNA 3GOVA 3M7PA 2G7IA 2CKUA 1FBRA 2MCYA 3ZD1A 1Z92B 3ZRZA 1TPMA 4AYIA 3MQLA 2RKZA 1E8BA 1OJVA 3RJ3D 3INBC 1Q3XA 1TPGA 4J38B 1LY2A 3NFPI 2XQWC 1O9AA 1OJWA 4LOTA 3KZJA 2EHFA 3GXEA 2JGWA 2W81A 1PPQA 1VVDA 1MD7A 1QGBA 2XWJI 1TPNA 4AYMA 1MD8A 1SS2A 2MCZA 4DJZA 1H04P 2JRAA 2CG6A 1ZJKA 2B5ID 4A5WB 3SW0X 4C16A 2LOJA 3IU3I 1HFIA 2A55A 1QO6A 1GKNA 2QY0A 3R62A 1OK9A 2V8EA 3ZD2A 5HYTB 4WJG2 1H03P 2RLPA 1H2QP 3OEDC 4ONTD 2XRDA 2RLQA 4YNXA 1H2PP 4KKDA 4LOSA 1E88A 3O8EB 5FO8C 2WIIC 3TVJA 1G4FA 1G4GA 4PZ5A 4AYEA 3L89M 1CKLA 1U5MA 2XRBA 1ELVA 4F4OC 1GHQB 3KXVA 3CALA 4B2SA 1SRZA 4ZH1D 2JGXA 5I0QB 4B2RA 2IZ4A 2BZMA 2O39C 1OK1A 1HCCA 2XWBF 4AYDA 2KMSA 1GPZA 4JHSA 5JPMG 5HZPB 4CSYA 4MUCA 1QUBA 2KRIA 2EC3A 5HYPA 3ERBA 1C1ZA 3IX0A 1OJYA 2IZ3A 1GKGA 3EJHA 2YRAA 4IGDA 1VVCA 1NWVA 1E5GA 1OK3A 3OP8A 3OXUD 1UOTP 1OK2A 4K12A 2RL0A 2W80A 2YBYA 5HYUB 2ERJA 2CG7A 4FXGG 1HFHA 2RKYA
chains in the Genus database with same CATH superfamily
3T5OA 2UWNA 3GOVA 3M7PA 2G7IA 4PO7A 2CKUA 1FBRA 2MCYA 3ZD1A 1Z92B 3ZRZA 2I2LA 1TPMA 4AYIA 3MQLA 2RKZA 2Y8TA 1E8BA 1OJVA 3RJ3D 3INBC 1Q3XA 1TPGA 5DN5A 4J38B 4MSLA 1LY2A 2X2ZA 4N7EA 3NFPI 2ZYCA 2XQWC 1O9AA 1OJWA 5DN4A 1RLHA 3FGRA 3KZJA 2EHFA 4LOTA 3GXEA 2JGWA 2W81A 1PPQA 1VVDA 1MD7A 1QGBA 2XWJI 1TPNA 4AYMA 1MD8A 1SS2A 2MCZA 4DJZA 1H04P 2JRAA 3ZLDA 2CG6A 1ZJKA 2B5ID 4A5WB 3SW0X 4C16A 2LOJA 3IU3I 1HFIA 2A55A 1QO6A 3WSXA 1GKNA 2QY0A 3R62A 1OK9A 2V8EA 3ZD2A 5HYTB 4WJG2 1H03P 2RLPA 1H2QP 3OEDC 4ONTD 2XRDA 2RLQA 4YNXA 1H2PP 4KKDA 4LOSA 1E88A 3O8EB 5FO8C 2WIIC 3TVJA 1G4FA 3F6KA 1G4GA 4PZ5A 4AYEA 3L89M 1CKLA 1U5MA 2XRBA 1ELVA 4F4OC 1GHQB 3KXVA 3CALA 4B2SA 1SRZA 4ZH1D 2JGXA 5I0QB 4B2RA 2IZ4A 2BZMA 2O39C 3CI0J 1OK1A 1HCCA 2XWBF 2Y8SA 2KMSA 1GPZA 4AYDA 4JHSA 5JPMG 3K3TA 5HZPB 4CSYA 4MUCA 1QUBA 2KRIA 2EC3A 5HYPA 3ERBA 1C1ZA 3IX0A 1OJYA 2IZ3A 1GKGA 3EJHA 2YRAA 4IGDA 3FGTA 3WSYA 1VVCA 1NWVA 1E5GA 1OK3A 4BWCA 3ZLEA 3OP8A 3OXUD 1UOTP 1OK2A 4APLA 4K12A 2RL0A 3VWOA 2W80A 4YIZA 2YBYA 5HYUB 2Y8RA 2ERJA 2CG7A 4FXGG 1HFHA 3NJAA 2RKYA
chains in the Genus database with same CATH topology
3T5OA 2UWNA 3GOVA 3M7PA 2G7IA 2CKUA 1FBRA 2MCYA 3ZD1A 1Z92B 3ZRZA 1TPMA 4AYIA 3MQLA 2RKZA 1E8BA 1OJVA 3RJ3D 3INBC 1Q3XA 1TPGA 4J38B 1LY2A 3NFPI 2XQWC 1O9AA 1OJWA 4LOTA 3KZJA 2EHFA 3GXEA 2JGWA 2W81A 1PPQA 1VVDA 1MD7A 1QGBA 2XWJI 1TPNA 4AYMA 1MD8A 1SS2A 2MCZA 4DJZA 1H04P 2JRAA 2CG6A 1ZJKA 2B5ID 4A5WB 3SW0X 4C16A 2LOJA 3IU3I 1HFIA 2A55A 1QO6A 1GKNA 2QY0A 3R62A 1OK9A 2V8EA 3ZD2A 5HYTB 4WJG2 1H03P 2RLPA 1H2QP 3OEDC 4ONTD 2XRDA 2RLQA 4YNXA 1H2PP 4KKDA 4LOSA 1E88A 3O8EB 5FO8C 2WIIC 3TVJA 1G4FA 1G4GA 4PZ5A 4AYEA 3L89M 1CKLA 1U5MA 2XRBA 1ELVA 4F4OC 1GHQB 3KXVA 3CALA 4B2SA 1SRZA 4ZH1D 2JGXA 5I0QB 4B2RA 2IZ4A 2BZMA 2O39C 1OK1A 1HCCA 2XWBF 4AYDA 2KMSA 1GPZA 4JHSA 5JPMG 5HZPB 4CSYA 4MUCA 1QUBA 2KRIA 2EC3A 5HYPA 3ERBA 1C1ZA 3IX0A 1OJYA 2IZ3A 1GKGA 3EJHA 2YRAA 4IGDA 1VVCA 1NWVA 1E5GA 1OK3A 3OP8A 3OXUD 1UOTP 1OK2A 4K12A 2RL0A 2W80A 2YBYA 5HYUB 2ERJA 2CG7A 4FXGG 1HFHA 2RKYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T5O A;  2UWN A;  3GOV A;  3M7P A;  2G7I A;  2CKU A;  1FBR A;  2MCY A;  3ZD1 A;  1Z92 B;  3ZRZ A;  1TPM A;  4AYI A;  3MQL A;  2RKZ A;  1E8B A;  1OJV A;  3RJ3 D;  3INB C;  1Q3X A;  1TPG A;  4J38 B;  1LY2 A;  3NFP I;  2XQW C;  1O9A A;  1OJW A;  4LOT A;  3KZJ A;  2EHF A;  3GXE A;  2JGW A;  2W81 A;  1PPQ A;  1VVD A;  1MD7 A;  1QGB A;  2XWJ I;  1TPN A;  4AYM A;  1MD8 A;  1SS2 A;  2MCZ A;  4DJZ A;  1H04 P;  2JRA A;  2CG6 A;  1ZJK A;  2B5I D;  4A5W B;  3SW0 X;  4C16 A;  2LOJ A;  3IU3 I;  1HFI A;  2A55 A;  1QO6 A;  1GKN A;  2QY0 A;  3R62 A;  1OK9 A;  2V8E A;  3ZD2 A;  5HYT B;  4WJG 2;  1H03 P;  2RLP A;  1H2Q P;  3OED C;  4ONT D;  2XRD A;  2RLQ A;  4YNX A;  1H2P P;  4KKD A;  4LOS A;  1E88 A;  3O8E B;  5FO8 C;  2WII C;  3TVJ A;  1G4F A;  1G4G A;  4PZ5 A;  4AYE A;  3L89 M;  1CKL A;  1U5M A;  2XRB A;  1ELV A;  4F4O C;  1GHQ B;  3KXV A;  3CAL A;  4B2S A;  1SRZ A;  4ZH1 D;  2JGX A;  5I0Q B;  4B2R A;  2IZ4 A;  2BZM A;  2O39 C;  1OK1 A;  1HCC A;  2XWB F;  4AYD A;  2KMS A;  1GPZ A;  4JHS A;  5JPM G;  5HZP B;  4CSY A;  4MUC A;  1QUB A;  2KRI A;  2EC3 A;  5HYP A;  3ERB A;  1C1Z A;  3IX0 A;  1OJY A;  2IZ3 A;  1GKG A;  3EJH A;  2YRA A;  4IGD A;  1VVC A;  1NWV A;  1E5G A;  1OK3 A;  3OP8 A;  3OXU D;  1UOT P;  1OK2 A;  4K12 A;  2RL0 A;  2W80 A;  2YBY A;  5HYU B;  2ERJ A;  2CG7 A;  4FXG G;  1HFH A;  2RKY A; 
#chains in the Genus database with same CATH topology
 3T5O A;  2UWN A;  3GOV A;  3M7P A;  2G7I A;  4PO7 A;  2CKU A;  1FBR A;  2MCY A;  3ZD1 A;  1Z92 B;  3ZRZ A;  2I2L A;  1TPM A;  4AYI A;  3MQL A;  2RKZ A;  2Y8T A;  1E8B A;  1OJV A;  3RJ3 D;  3INB C;  1Q3X A;  1TPG A;  5DN5 A;  4J38 B;  4MSL A;  1LY2 A;  2X2Z A;  4N7E A;  3NFP I;  2ZYC A;  2XQW C;  1O9A A;  1OJW A;  5DN4 A;  1RLH A;  3FGR A;  3KZJ A;  2EHF A;  4LOT A;  3GXE A;  2JGW A;  2W81 A;  1PPQ A;  1VVD A;  1MD7 A;  1QGB A;  2XWJ I;  1TPN A;  4AYM A;  1MD8 A;  1SS2 A;  2MCZ A;  4DJZ A;  1H04 P;  2JRA A;  3ZLD A;  2CG6 A;  1ZJK A;  2B5I D;  4A5W B;  3SW0 X;  4C16 A;  2LOJ A;  3IU3 I;  1HFI A;  2A55 A;  1QO6 A;  3WSX A;  1GKN A;  2QY0 A;  3R62 A;  1OK9 A;  2V8E A;  3ZD2 A;  5HYT B;  4WJG 2;  1H03 P;  2RLP A;  1H2Q P;  3OED C;  4ONT D;  2XRD A;  2RLQ A;  4YNX A;  1H2P P;  4KKD A;  4LOS A;  1E88 A;  3O8E B;  5FO8 C;  2WII C;  3TVJ A;  1G4F A;  3F6K A;  1G4G A;  4PZ5 A;  4AYE A;  3L89 M;  1CKL A;  1U5M A;  2XRB A;  1ELV A;  4F4O C;  1GHQ B;  3KXV A;  3CAL A;  4B2S A;  1SRZ A;  4ZH1 D;  2JGX A;  5I0Q B;  4B2R A;  2IZ4 A;  2BZM A;  2O39 C;  3CI0 J;  1OK1 A;  1HCC A;  2XWB F;  2Y8S A;  2KMS A;  1GPZ A;  4AYD A;  4JHS A;  5JPM G;  3K3T A;  5HZP B;  4CSY A;  4MUC A;  1QUB A;  2KRI A;  2EC3 A;  5HYP A;  3ERB A;  1C1Z A;  3IX0 A;  1OJY A;  2IZ3 A;  1GKG A;  3EJH A;  2YRA A;  4IGD A;  3FGT A;  3WSY A;  1VVC A;  1NWV A;  1E5G A;  1OK3 A;  4BWC A;  3ZLE A;  3OP8 A;  3OXU D;  1UOT P;  1OK2 A;  4APL A;  4K12 A;  2RL0 A;  3VWO A;  2W80 A;  4YIZ A;  2YBY A;  5HYU B;  2Y8R A;  2ERJ A;  2CG7 A;  4FXG G;  1HFH A;  3NJA A;  2RKY A; 
#chains in the Genus database with same CATH homology
 3T5O A;  2UWN A;  3GOV A;  3M7P A;  2G7I A;  2CKU A;  1FBR A;  2MCY A;  3ZD1 A;  1Z92 B;  3ZRZ A;  1TPM A;  4AYI A;  3MQL A;  2RKZ A;  1E8B A;  1OJV A;  3RJ3 D;  3INB C;  1Q3X A;  1TPG A;  4J38 B;  1LY2 A;  3NFP I;  2XQW C;  1O9A A;  1OJW A;  4LOT A;  3KZJ A;  2EHF A;  3GXE A;  2JGW A;  2W81 A;  1PPQ A;  1VVD A;  1MD7 A;  1QGB A;  2XWJ I;  1TPN A;  4AYM A;  1MD8 A;  1SS2 A;  2MCZ A;  4DJZ A;  1H04 P;  2JRA A;  2CG6 A;  1ZJK A;  2B5I D;  4A5W B;  3SW0 X;  4C16 A;  2LOJ A;  3IU3 I;  1HFI A;  2A55 A;  1QO6 A;  1GKN A;  2QY0 A;  3R62 A;  1OK9 A;  2V8E A;  3ZD2 A;  5HYT B;  4WJG 2;  1H03 P;  2RLP A;  1H2Q P;  3OED C;  4ONT D;  2XRD A;  2RLQ A;  4YNX A;  1H2P P;  4KKD A;  4LOS A;  1E88 A;  3O8E B;  5FO8 C;  2WII C;  3TVJ A;  1G4F A;  1G4G A;  4PZ5 A;  4AYE A;  3L89 M;  1CKL A;  1U5M A;  2XRB A;  1ELV A;  4F4O C;  1GHQ B;  3KXV A;  3CAL A;  4B2S A;  1SRZ A;  4ZH1 D;  2JGX A;  5I0Q B;  4B2R A;  2IZ4 A;  2BZM A;  2O39 C;  1OK1 A;  1HCC A;  2XWB F;  4AYD A;  2KMS A;  1GPZ A;  4JHS A;  5JPM G;  5HZP B;  4CSY A;  4MUC A;  1QUB A;  2KRI A;  2EC3 A;  5HYP A;  3ERB A;  1C1Z A;  3IX0 A;  1OJY A;  2IZ3 A;  1GKG A;  3EJH A;  2YRA A;  4IGD A;  1VVC A;  1NWV A;  1E5G A;  1OK3 A;  3OP8 A;  3OXU D;  1UOT P;  1OK2 A;  4K12 A;  2RL0 A;  2W80 A;  2YBY A;  5HYU B;  2ERJ A;  2CG7 A;  4FXG G;  1HFH A;  2RKY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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