5EYVA

Crystal structure of adenylosuccinate lyase from schistosoma mansoni in apo form.
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
476
structure length
466
Chain Sequence
FEEYRNPLTKRYASREMVCNFGEKRKVILWRQLWIWLAETQKELGFDITDEQINEMKSQRDSVDFGTAAAEEKARRHDVMAHVYTFALACPKAAPIIHLGATSCFVGDNADLIMLKDGLNILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLERLKNHTIRFRGAKGAVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRKVDIEITNALSNIGATVHKICTDIRLLSSFHEVEEPFETKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIAEGLIVYPMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLKGLKNSLMDKLLNDYYFAPIHSLLPTVLDPSYMIGRAVEQVEVFLNTEVDPAIHSYKDCLALNSNIT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
pubmed doi rcsb
molecule tags Lyase
source organism Schistosoma mansoni
molecule keywords Adenylosuccinate lyase
total genus 170
structure length 466
sequence length 476
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2015-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 5eyvA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 5eyvA02
2J91A 1U15A 3RRPA 2O7EA 5EYVA 3UNVA 1GK2A 3R6QA 3RD8A 1J3UA 2YIIA 1TJVA 4C5UA 2O7DA 4ADLA 4BABA 1C3UA 1K7WA 2NYFA 5EYTA 1TJUA 2QGAB 1YFMA 1Y2MA 1C3CA 1FUOA 4FLCA 3QBPA 2VD6A 4C5RA 4CQ5A 3TV2A 2PFMA 3OCFA 3KDYA 2NYNA 4C5SA 2HVGA 2QVEA 2X75A 1GK3A 5F91A 1TJ7A 2FUSA 4BAAA 1I0AA 2O7FA 1AUWA 1KQ7A 3R6YA 5F92A 2O78A 1T6JA 1EB4A 1DCNA 1Q5NA 1U16A 5HW2A 4APAA 2RJRA 1VDKA 4NSLA 4V2QA 4V2RA 3R6VA 1YISA 4EEIA 1YFEA 3BHGA 4ADMA 2PTQA 3NZ4A 4MX2A 1T6PA 1FUQA 3E04A 1JSWA 1TJWA 1RE5A 1W27A 3NO9A 2PTRA 1GKJA 5D6BA 4APBA 2OHYA 2E9FA 3OCEA 4C6GA 2O6YA 3CZOA 2PTSA 4FFXA 4EFCA 1HY1A 3KDZA 1FURA 1K62A 1FUPA 2O7BA 1XWOA 4NLEA 3GTDA 1GKMA 3GZHA 4HGVA 1B8FA 1DOFA 2RJSA 3C8TA 1HY0A
chains in the Genus database with same CATH superfamily
2J91A 1U15A 3RRPA 2O7EA 5EYVA 3UNVA 1GK2A 3R6QA 3RD8A 1J3UA 2YIIA 1TJVA 4C5UA 2O7DA 4ADLA 4BABA 1C3UA 1K7WA 2NYFA 5EYTA 1TJUA 1XLYA 2QGAB 1YFMA 1Y2MA 1C3CA 1FUOA 4FLCA 3QBPA 2VD6A 1XMCA 4C5RA 4CQ5A 3TV2A 3CRVA 2PFMA 3OCFA 3KDYA 2NYNA 4C5SA 2HVGA 1XL8A 2QVEA 2X75A 1GK3A 5F91A 1TJ7A 4WNLA 2FUSA 4BAAA 1I0AA 2O7FA 1AUWA 1XL7A 1KQ7A 3R6YA 5F92A 2O78A 1T6JA 1EB4A 1DCNA 1Q5NA 1U16A 5HW2A 4APAA 2RJRA 1VDKA 4NSLA 4V2QA 4V2RA 3R6VA 1YISA 4EEIA 1YFEA 3BHGA 4ADMA 2PTQA 3NZ4A 4MX2A 1T6PA 1FUQA 3E04A 2FELA 5H8WA 1JSWA 1TJWA 1RE5A 1W27A 3NO9A 2PTRA 1GKJA 2VSFA 5D6BA 4APBA 2OHYA 2E9FA 3OCEA 2VL7A 4C6GA 2O6YA 3CRW1 3CZOA 1XMDA 2PTSA 4FFXA 4EFCA 1HY1A 3KDZA 1FURA 1K62A 1FUPA 2O7BA 1XWOA 4NLEA 5M0JA 4A15A 3GTDA 5M0IA 2FENA 1GKMA 3GZHA 4HGVA 1B8FA 1DOFA 2RJSA 3C8TA 1HY0A
chains in the Genus database with same CATH topology
2J91A 1U15A 3RRPA 2O7EA 5EYVA 3UNVA 1GK2A 3R6QA 3RD8A 1J3UA 2YIIA 1TJVA 4C5UA 2O7DA 4ADLA 4BABA 1C3UA 1K7WA 2NYFA 5EYTA 1TJUA 2QGAB 1YFMA 1Y2MA 1C3CA 1FUOA 4FLCA 3QBPA 2VD6A 4C5RA 4CQ5A 3TV2A 2PFMA 3OCFA 3KDYA 2NYNA 4C5SA 2HVGA 2QVEA 2X75A 1GK3A 5F91A 1TJ7A 2FUSA 4BAAA 1I0AA 2O7FA 1AUWA 1KQ7A 3R6YA 5F92A 2O78A 1T6JA 1EB4A 1DCNA 1Q5NA 1U16A 5HW2A 4APAA 2RJRA 1VDKA 4NSLA 4V2QA 4V2RA 3R6VA 1YISA 4EEIA 1YFEA 3BHGA 4ADMA 2PTQA 3NZ4A 4MX2A 1T6PA 1FUQA 3E04A 1JSWA 1TJWA 1RE5A 1W27A 3NO9A 2PTRA 1GKJA 5D6BA 4APBA 2OHYA 2E9FA 3OCEA 4C6GA 2O6YA 3CZOA 2PTSA 4FFXA 4EFCA 1HY1A 3KDZA 1FURA 1K62A 1FUPA 2O7BA 1XWOA 4NLEA 3GTDA 1GKMA 3GZHA 4HGVA 1B8FA 1DOFA 2RJSA 3C8TA 1HY0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J91 A;  1U15 A;  3RRP A;  2O7E A;  5EYV A;  3UNV A;  1GK2 A;  3R6Q A;  3RD8 A;  1J3U A;  2YII A;  1TJV A;  4C5U A;  2O7D A;  4ADL A;  4BAB A;  1C3U A;  1K7W A;  2NYF A;  5EYT A;  1TJU A;  2QGA B;  1YFM A;  1Y2M A;  1C3C A;  1FUO A;  4FLC A;  3QBP A;  2VD6 A;  4C5R A;  4CQ5 A;  3TV2 A;  2PFM A;  3OCF A;  3KDY A;  2NYN A;  4C5S A;  2HVG A;  2QVE A;  2X75 A;  1GK3 A;  5F91 A;  1TJ7 A;  2FUS A;  4BAA A;  1I0A A;  2O7F A;  1AUW A;  1KQ7 A;  3R6Y A;  5F92 A;  2O78 A;  1T6J A;  1EB4 A;  1DCN A;  1Q5N A;  1U16 A;  5HW2 A;  4APA A;  2RJR A;  1VDK A;  4NSL A;  4V2Q A;  4V2R A;  3R6V A;  1YIS A;  4EEI A;  1YFE A;  3BHG A;  4ADM A;  2PTQ A;  3NZ4 A;  4MX2 A;  1T6P A;  1FUQ A;  3E04 A;  1JSW A;  1TJW A;  1RE5 A;  1W27 A;  3NO9 A;  2PTR A;  1GKJ A;  5D6B A;  4APB A;  2OHY A;  2E9F A;  3OCE A;  4C6G A;  2O6Y A;  3CZO A;  2PTS A;  4FFX A;  4EFC A;  1HY1 A;  3KDZ A;  1FUR A;  1K62 A;  1FUP A;  2O7B A;  1XWO A;  4NLE A;  3GTD A;  1GKM A;  3GZH A;  4HGV A;  1B8F A;  1DOF A;  2RJS A;  3C8T A;  1HY0 A; 
#chains in the Genus database with same CATH topology
 2J91 A;  1U15 A;  3RRP A;  2O7E A;  5EYV A;  3UNV A;  1GK2 A;  3R6Q A;  3RD8 A;  1J3U A;  2YII A;  1TJV A;  4C5U A;  2O7D A;  4ADL A;  4BAB A;  1C3U A;  1K7W A;  2NYF A;  5EYT A;  1TJU A;  1XLY A;  2QGA B;  1YFM A;  1Y2M A;  1C3C A;  1FUO A;  4FLC A;  3QBP A;  2VD6 A;  1XMC A;  4C5R A;  4CQ5 A;  3TV2 A;  3CRV A;  2PFM A;  3OCF A;  3KDY A;  2NYN A;  4C5S A;  2HVG A;  1XL8 A;  2QVE A;  2X75 A;  1GK3 A;  5F91 A;  1TJ7 A;  4WNL A;  2FUS A;  4BAA A;  1I0A A;  2O7F A;  1AUW A;  1XL7 A;  1KQ7 A;  3R6Y A;  5F92 A;  2O78 A;  1T6J A;  1EB4 A;  1DCN A;  1Q5N A;  1U16 A;  5HW2 A;  4APA A;  2RJR A;  1VDK A;  4NSL A;  4V2Q A;  4V2R A;  3R6V A;  1YIS A;  4EEI A;  1YFE A;  3BHG A;  4ADM A;  2PTQ A;  3NZ4 A;  4MX2 A;  1T6P A;  1FUQ A;  3E04 A;  2FEL A;  5H8W A;  1JSW A;  1TJW A;  1RE5 A;  1W27 A;  3NO9 A;  2PTR A;  1GKJ A;  2VSF A;  5D6B A;  4APB A;  2OHY A;  2E9F A;  3OCE A;  2VL7 A;  4C6G A;  2O6Y A;  3CRW 1;  3CZO A;  1XMD A;  2PTS A;  4FFX A;  4EFC A;  1HY1 A;  3KDZ A;  1FUR A;  1K62 A;  1FUP A;  2O7B A;  1XWO A;  4NLE A;  5M0J A;  4A15 A;  3GTD A;  5M0I A;  2FEN A;  1GKM A;  3GZH A;  4HGV A;  1B8F A;  1DOF A;  2RJS A;  3C8T A;  1HY0 A; 
#chains in the Genus database with same CATH homology
 2J91 A;  1U15 A;  3RRP A;  2O7E A;  5EYV A;  3UNV A;  1GK2 A;  3R6Q A;  3RD8 A;  1J3U A;  2YII A;  1TJV A;  4C5U A;  2O7D A;  4ADL A;  4BAB A;  1C3U A;  1K7W A;  2NYF A;  5EYT A;  1TJU A;  2QGA B;  1YFM A;  1Y2M A;  1C3C A;  1FUO A;  4FLC A;  3QBP A;  2VD6 A;  4C5R A;  4CQ5 A;  3TV2 A;  2PFM A;  3OCF A;  3KDY A;  2NYN A;  4C5S A;  2HVG A;  2QVE A;  2X75 A;  1GK3 A;  5F91 A;  1TJ7 A;  2FUS A;  4BAA A;  1I0A A;  2O7F A;  1AUW A;  1KQ7 A;  3R6Y A;  5F92 A;  2O78 A;  1T6J A;  1EB4 A;  1DCN A;  1Q5N A;  1U16 A;  5HW2 A;  4APA A;  2RJR A;  1VDK A;  4NSL A;  4V2Q A;  4V2R A;  3R6V A;  1YIS A;  4EEI A;  1YFE A;  3BHG A;  4ADM A;  2PTQ A;  3NZ4 A;  4MX2 A;  1T6P A;  1FUQ A;  3E04 A;  1JSW A;  1TJW A;  1RE5 A;  1W27 A;  3NO9 A;  2PTR A;  1GKJ A;  5D6B A;  4APB A;  2OHY A;  2E9F A;  3OCE A;  4C6G A;  2O6Y A;  3CZO A;  2PTS A;  4FFX A;  4EFC A;  1HY1 A;  3KDZ A;  1FUR A;  1K62 A;  1FUP A;  2O7B A;  1XWO A;  4NLE A;  3GTD A;  1GKM A;  3GZH A;  4HGV A;  1B8F A;  1DOF A;  2RJS A;  3C8T A;  1HY0 A; 
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