5EYVA

Crystal structure of adenylosuccinate lyase from schistosoma mansoni in apo form.
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
476
structure length
466
Chain Sequence
FEEYRNPLTKRYASREMVCNFGEKRKVILWRQLWIWLAETQKELGFDITDEQINEMKSQRDSVDFGTAAAEEKARRHDVMAHVYTFALACPKAAPIIHLGATSCFVGDNADLIMLKDGLNILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLERLKNHTIRFRGAKGAVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRKVDIEITNALSNIGATVHKICTDIRLLSSFHEVEEPFETKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIAEGLIVYPMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLKGLKNSLMDKLLNDYYFAPIHSLLPTVLDPSYMIGRAVEQVEVFLNTEVDPAIHSYKDCLALNSNIT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
pubmed doi rcsb
molecule tags Lyase
source organism Schistosoma mansoni
molecule keywords Adenylosuccinate lyase
total genus 170
structure length 466
sequence length 476
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2015-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 5eyvA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 5eyvA02
2O7EA 1YFMA 1DCNA 5F91A 1FUPA 3R6VA 2O78A 4ADLA 3UNVA 3KDZA 4HGVA 4BABA 3GTDA 2RJSA 3RRPA 1TJVA 1YISA 3CZOA 2NYNA 4CQ5A 4EFCA 1C3UA 3KDYA 3E04A 1W27A 1JSWA 2E9FA 1TJWA 1YFEA 1TJ7A 4BAAA 4NLEA 4MX2A 1Q5NA 3NZ4A 1FUOA 2X75A 3BHGA 3OCEA 1T6JA 3RD8A 4C5SA 4APBA 2O7BA 1C3CA 3QBPA 1K7WA 5EYVA 4C5UA 1GKMA 3GZHA 3OCFA 1FURA 3NO9A 2YIIA 2PTRA 1GKJA 3TV2A 4V2RA 1T6PA 2NYFA 4FFXA 5F92A 1I0AA 2OHYA 1Y2MA 1AUWA 2QGAB 4FLCA 2PTQA 1EB4A 2RJRA 5HW2A 1RE5A 2PTSA 2FUSA 1J3UA 1TJUA 1U16A 4C5RA 1B8FA 2HVGA 5EYTA 1K62A 2PFMA 2J91A 4NSLA 4ADMA 1XWOA 4APAA 5D6BA 1U15A 1KQ7A 4V2QA 2O6YA 3R6YA 1HY1A 1DOFA 1HY0A 2QVEA 1GK3A 1VDKA 2VD6A 4C6GA 2O7DA 1GK2A 4EEIA 3C8TA 2O7FA 3R6QA 1FUQA
chains in the Genus database with same CATH superfamily
2O7EA 1YFMA 1DCNA 1XLYA 5F91A 1FUPA 3R6VA 2O78A 4ADLA 3UNVA 3KDZA 4HGVA 4BABA 3GTDA 2RJSA 3RRPA 5H8WA 1TJVA 1YISA 3CZOA 2NYNA 4CQ5A 4EFCA 1XMCA 1C3UA 3KDYA 3E04A 1W27A 1JSWA 2E9FA 1TJWA 2VL7A 1YFEA 5M0JA 1TJ7A 1XL8A 4BAAA 4WNLA 4NLEA 4MX2A 1Q5NA 3NZ4A 1FUOA 2X75A 3BHGA 3OCEA 1T6JA 3RD8A 4C5SA 4APBA 2O7BA 1C3CA 3CRVA 3QBPA 1K7WA 5EYVA 4C5UA 1GKMA 3GZHA 3OCFA 1FURA 3NO9A 2VSFA 2YIIA 2PTRA 1GKJA 3TV2A 4V2RA 1T6PA 2NYFA 4FFXA 5F92A 1I0AA 2OHYA 1Y2MA 1AUWA 2QGAB 3CRW1 4FLCA 2PTQA 5M0IA 1EB4A 2RJRA 5HW2A 1RE5A 2PTSA 2FUSA 1XL7A 1J3UA 1TJUA 1U16A 4C5RA 1B8FA 2HVGA 5EYTA 1K62A 2PFMA 2J91A 4NSLA 4ADMA 1XWOA 4APAA 5D6BA 1U15A 1KQ7A 4V2QA 2O6YA 4A15A 1XMDA 3R6YA 2FENA 1HY1A 1DOFA 1HY0A 2QVEA 1GK3A 1VDKA 2VD6A 4C6GA 2O7DA 1GK2A 4EEIA 3C8TA 2O7FA 3R6QA 1FUQA 2FELA
chains in the Genus database with same CATH topology
2O7EA 1YFMA 1DCNA 5F91A 1FUPA 3R6VA 2O78A 4ADLA 3UNVA 3KDZA 4HGVA 4BABA 3GTDA 2RJSA 3RRPA 1TJVA 1YISA 3CZOA 2NYNA 4CQ5A 4EFCA 1C3UA 3KDYA 3E04A 1W27A 1JSWA 2E9FA 1TJWA 1YFEA 1TJ7A 4BAAA 4NLEA 4MX2A 1Q5NA 3NZ4A 1FUOA 2X75A 3BHGA 3OCEA 1T6JA 3RD8A 4C5SA 4APBA 2O7BA 1C3CA 3QBPA 1K7WA 5EYVA 4C5UA 1GKMA 3GZHA 3OCFA 1FURA 3NO9A 2YIIA 2PTRA 1GKJA 3TV2A 4V2RA 1T6PA 2NYFA 4FFXA 5F92A 1I0AA 2OHYA 1Y2MA 1AUWA 2QGAB 4FLCA 2PTQA 1EB4A 2RJRA 5HW2A 1RE5A 2PTSA 2FUSA 1J3UA 1TJUA 1U16A 4C5RA 1B8FA 2HVGA 5EYTA 1K62A 2PFMA 2J91A 4NSLA 4ADMA 1XWOA 4APAA 5D6BA 1U15A 1KQ7A 4V2QA 2O6YA 3R6YA 1HY1A 1DOFA 1HY0A 2QVEA 1GK3A 1VDKA 2VD6A 4C6GA 2O7DA 1GK2A 4EEIA 3C8TA 2O7FA 3R6QA 1FUQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O7E A;  1YFM A;  1DCN A;  5F91 A;  1FUP A;  3R6V A;  2O78 A;  4ADL A;  3UNV A;  3KDZ A;  4HGV A;  4BAB A;  3GTD A;  2RJS A;  3RRP A;  1TJV A;  1YIS A;  3CZO A;  2NYN A;  4CQ5 A;  4EFC A;  1C3U A;  3KDY A;  3E04 A;  1W27 A;  1JSW A;  2E9F A;  1TJW A;  1YFE A;  1TJ7 A;  4BAA A;  4NLE A;  4MX2 A;  1Q5N A;  3NZ4 A;  1FUO A;  2X75 A;  3BHG A;  3OCE A;  1T6J A;  3RD8 A;  4C5S A;  4APB A;  2O7B A;  1C3C A;  3QBP A;  1K7W A;  5EYV A;  4C5U A;  1GKM A;  3GZH A;  3OCF A;  1FUR A;  3NO9 A;  2YII A;  2PTR A;  1GKJ A;  3TV2 A;  4V2R A;  1T6P A;  2NYF A;  4FFX A;  5F92 A;  1I0A A;  2OHY A;  1Y2M A;  1AUW A;  2QGA B;  4FLC A;  2PTQ A;  1EB4 A;  2RJR A;  5HW2 A;  1RE5 A;  2PTS A;  2FUS A;  1J3U A;  1TJU A;  1U16 A;  4C5R A;  1B8F A;  2HVG A;  5EYT A;  1K62 A;  2PFM A;  2J91 A;  4NSL A;  4ADM A;  1XWO A;  4APA A;  5D6B A;  1U15 A;  1KQ7 A;  4V2Q A;  2O6Y A;  3R6Y A;  1HY1 A;  1DOF A;  1HY0 A;  2QVE A;  1GK3 A;  1VDK A;  2VD6 A;  4C6G A;  2O7D A;  1GK2 A;  4EEI A;  3C8T A;  2O7F A;  3R6Q A;  1FUQ A; 
#chains in the Genus database with same CATH topology
 2O7E A;  1YFM A;  1DCN A;  1XLY A;  5F91 A;  1FUP A;  3R6V A;  2O78 A;  4ADL A;  3UNV A;  3KDZ A;  4HGV A;  4BAB A;  3GTD A;  2RJS A;  3RRP A;  5H8W A;  1TJV A;  1YIS A;  3CZO A;  2NYN A;  4CQ5 A;  4EFC A;  1XMC A;  1C3U A;  3KDY A;  3E04 A;  1W27 A;  1JSW A;  2E9F A;  1TJW A;  2VL7 A;  1YFE A;  5M0J A;  1TJ7 A;  1XL8 A;  4BAA A;  4WNL A;  4NLE A;  4MX2 A;  1Q5N A;  3NZ4 A;  1FUO A;  2X75 A;  3BHG A;  3OCE A;  1T6J A;  3RD8 A;  4C5S A;  4APB A;  2O7B A;  1C3C A;  3CRV A;  3QBP A;  1K7W A;  5EYV A;  4C5U A;  1GKM A;  3GZH A;  3OCF A;  1FUR A;  3NO9 A;  2VSF A;  2YII A;  2PTR A;  1GKJ A;  3TV2 A;  4V2R A;  1T6P A;  2NYF A;  4FFX A;  5F92 A;  1I0A A;  2OHY A;  1Y2M A;  1AUW A;  2QGA B;  3CRW 1;  4FLC A;  2PTQ A;  5M0I A;  1EB4 A;  2RJR A;  5HW2 A;  1RE5 A;  2PTS A;  2FUS A;  1XL7 A;  1J3U A;  1TJU A;  1U16 A;  4C5R A;  1B8F A;  2HVG A;  5EYT A;  1K62 A;  2PFM A;  2J91 A;  4NSL A;  4ADM A;  1XWO A;  4APA A;  5D6B A;  1U15 A;  1KQ7 A;  4V2Q A;  2O6Y A;  4A15 A;  1XMD A;  3R6Y A;  2FEN A;  1HY1 A;  1DOF A;  1HY0 A;  2QVE A;  1GK3 A;  1VDK A;  2VD6 A;  4C6G A;  2O7D A;  1GK2 A;  4EEI A;  3C8T A;  2O7F A;  3R6Q A;  1FUQ A;  2FEL A; 
#chains in the Genus database with same CATH homology
 2O7E A;  1YFM A;  1DCN A;  5F91 A;  1FUP A;  3R6V A;  2O78 A;  4ADL A;  3UNV A;  3KDZ A;  4HGV A;  4BAB A;  3GTD A;  2RJS A;  3RRP A;  1TJV A;  1YIS A;  3CZO A;  2NYN A;  4CQ5 A;  4EFC A;  1C3U A;  3KDY A;  3E04 A;  1W27 A;  1JSW A;  2E9F A;  1TJW A;  1YFE A;  1TJ7 A;  4BAA A;  4NLE A;  4MX2 A;  1Q5N A;  3NZ4 A;  1FUO A;  2X75 A;  3BHG A;  3OCE A;  1T6J A;  3RD8 A;  4C5S A;  4APB A;  2O7B A;  1C3C A;  3QBP A;  1K7W A;  5EYV A;  4C5U A;  1GKM A;  3GZH A;  3OCF A;  1FUR A;  3NO9 A;  2YII A;  2PTR A;  1GKJ A;  3TV2 A;  4V2R A;  1T6P A;  2NYF A;  4FFX A;  5F92 A;  1I0A A;  2OHY A;  1Y2M A;  1AUW A;  2QGA B;  4FLC A;  2PTQ A;  1EB4 A;  2RJR A;  5HW2 A;  1RE5 A;  2PTS A;  2FUS A;  1J3U A;  1TJU A;  1U16 A;  4C5R A;  1B8F A;  2HVG A;  5EYT A;  1K62 A;  2PFM A;  2J91 A;  4NSL A;  4ADM A;  1XWO A;  4APA A;  5D6B A;  1U15 A;  1KQ7 A;  4V2Q A;  2O6Y A;  3R6Y A;  1HY1 A;  1DOF A;  1HY0 A;  2QVE A;  1GK3 A;  1VDK A;  2VD6 A;  4C6G A;  2O7D A;  1GK2 A;  4EEI A;  3C8T A;  2O7F A;  3R6Q A;  1FUQ A; 
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