5HYP | Genus

Total Genus 16

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	16
sequence length	125
structure length	125
Chain Sequence	SNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5d0dd0f351914cbc44476988/pdb.gz

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The Resolver thinks Pdb

loadScript /static/js/j2s/core/corebio.z.js

Time for openFile(/file/5d0dd0f351914cbc44476988/pdb.gz): 1665 ms

reading 125 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

125 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 18 ms

Adding embedded #jmolscript: select ({0:124});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Immune system
source organism	Homo sapiens
publication title	Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein. pubmed doi rcsb
molecule keywords	C4b-binding protein alpha chain
total genus	16
structure length	125
sequence length	125
ec nomenclature
pdb deposition date	2016-02-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00084	Sushi	Sushi repeat (SCR repeat)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.10.70.10	Mainly Beta	Ribbon	Complement Module; domain 1	Complement Module, domain 1	5hypA02
2.10.70.10	Mainly Beta	Ribbon	Complement Module; domain 1	Complement Module, domain 1	5hypA01

1ZJKA 2XQWC 2JRAA 2RLQA 1C1ZA 2EC3A 3ERBA 2XRBA 1GKGA 1VVDA 1HCCA 1TPGA 4F4OC 4WJG2 4K12A 1HFIA 4DJZA 1QUBA 3MQLA 1GPZA 4ONTD 1H03P 2KMSA 2QY0A 1PPQA 1MD8A 4AYDA 5HZPB 1OK3A 4JHSA 1E8BA 2A55A 3GOVA 4AYEA 1VVCA 4CSYA 2XRDA 5HYTB 2XWBF 1UOTP 1FBRA 1Q3XA 1SS2A 5JPMG 1Z92B 3OEDC 3TVJA 2MCZA 4LOSA 2RL0A 4AYMA 2XWJI 1H04P 4YNXA 3ZD2A 3ZRZA 1QGBA 1H2PP 2UWNA 3CALA 1OJYA 2CG7A 2B5ID 2V8EA 4J38B 2KRIA 3KZJA 4B2RA 1SRZA 1LY2A 2O39C 2IZ4A 3O8EB 1G4GA 3GXEA 2W81A 1MD7A 4A5WB 2BZMA 1TPMA 3L89M 2JGWA 2RKZA 1H2QP 5HYPA 2CKUA 2RKYA 2LOJA 2WIIC 2YRAA 5I0QB 4PZ5A 1U5MA 3T5OA 1HFHA 4AYIA 1OJVA 3ZD1A 3SW0X 2ERJA 4KKDA 2MCYA 3IU3I 5FO8C 2EHFA 4C16A 4IGDA 1G4FA 1E5GA 2CG6A 2JGXA 1QO6A 1OK1A 3M7PA 2YBYA 1TPNA 3IX0A 3EJHA 1GHQB 4LOTA 3RJ3D 3OXUD 2W80A 4FXGG 1OJWA 3KXVA 3INBC 1CKLA 4MUCA 2G7IA 2IZ3A 1GKNA 1E88A 1OK9A 1NWVA 1O9AA 2RLPA 1ELVA 3R62A 3NFPI 5HYUB 4B2SA 4ZH1D 3OP8A 1OK2A
chains in the Genus database with same CATH superfamily

1ZJKA 2XQWC 2JRAA 4N7EA 2RLQA 1C1ZA 2EC3A 3ERBA 2XRBA 1GKGA 1VVDA 1HCCA 3ZLDA 1TPGA 2I2LA 4F4OC 4WJG2 4K12A 1HFIA 4DJZA 1QUBA 3MQLA 1GPZA 4ONTD 1H03P 2KMSA 2QY0A 1PPQA 1MD8A 4AYDA 4MSLA 5HZPB 1OK3A 4JHSA 1E8BA 2A55A 3GOVA 4AYEA 5DN4A 1VVCA 4CSYA 2XRDA 4PO7A 5HYTB 2XWBF 1UOTP 1FBRA 1Q3XA 1SS2A 5JPMG 1Z92B 3OEDC 3TVJA 2MCZA 3ZLEA 4LOSA 2RL0A 4AYMA 3WSXA 2XWJI 1H04P 4YNXA 3ZD2A 3ZRZA 1QGBA 1H2PP 2UWNA 3CALA 1OJYA 2CG7A 2B5ID 2V8EA 4J38B 2KRIA 3KZJA 4B2RA 1SRZA 2Y8RA 1LY2A 2O39C 2IZ4A 3O8EB 1G4GA 3GXEA 2W81A 1MD7A 4A5WB 2BZMA 1TPMA 3L89M 2JGWA 2RKZA 2Y8SA 1H2QP 5HYPA 2X2ZA 2CKUA 2RKYA 2LOJA 2WIIC 2YRAA 5I0QB 2ZYCA 4PZ5A 1U5MA 3T5OA 3NJAA 3WSYA 1HFHA 4AYIA 1RLHA 1OJVA 3ZD1A 3SW0X 3FGRA 2ERJA 3FGTA 4KKDA 2MCYA 3IU3I 3F6KA 5FO8C 3VWOA 2EHFA 4C16A 4IGDA 1G4FA 1E5GA 2CG6A 2JGXA 1QO6A 3K3TA 1OK1A 3M7PA 2YBYA 1TPNA 3IX0A 3EJHA 4BWCA 4YIZA 1GHQB 4LOTA 3RJ3D 3OXUD 2W80A 4APLA 4FXGG 1OJWA 3KXVA 3INBC 1CKLA 4MUCA 2G7IA 2IZ3A 3CI0J 5DN5A 1E88A 1OK9A 1GKNA 1NWVA 1O9AA 2RLPA 1ELVA 2Y8TA 3R62A 3NFPI 5HYUB 4B2SA 4ZH1D 3OP8A 1OK2A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1ZJK A;  2XQW C;  2JRA A;  2RLQ A;  1C1Z A;  2EC3 A;  3ERB A;  2XRB A;  1GKG A;  1VVD A;  1HCC A;  1TPG A;  4F4O C;  4WJG 2;  4K12 A;  1HFI A;  4DJZ A;  1QUB A;  3MQL A;  1GPZ A;  4ONT D;  1H03 P;  2KMS A;  2QY0 A;  1PPQ A;  1MD8 A;  4AYD A;  5HZP B;  1OK3 A;  4JHS A;  1E8B A;  2A55 A;  3GOV A;  4AYE A;  1VVC A;  4CSY A;  2XRD A;  5HYT B;  2XWB F;  1UOT P;  1FBR A;  1Q3X A;  1SS2 A;  5JPM G;  1Z92 B;  3OED C;  3TVJ A;  2MCZ A;  4LOS A;  2RL0 A;  4AYM A;  2XWJ I;  1H04 P;  4YNX A;  3ZD2 A;  3ZRZ A;  1QGB A;  1H2P P;  2UWN A;  3CAL A;  1OJY A;  2CG7 A;  2B5I D;  2V8E A;  4J38 B;  2KRI A;  3KZJ A;  4B2R A;  1SRZ A;  1LY2 A;  2O39 C;  2IZ4 A;  3O8E B;  1G4G A;  3GXE A;  2W81 A;  1MD7 A;  4A5W B;  2BZM A;  1TPM A;  3L89 M;  2JGW A;  2RKZ A;  1H2Q P;  5HYP A;  2CKU A;  2RKY A;  2LOJ A;  2WII C;  2YRA A;  5I0Q B;  4PZ5 A;  1U5M A;  3T5O A;  1HFH A;  4AYI A;  1OJV A;  3ZD1 A;  3SW0 X;  2ERJ A;  4KKD A;  2MCY A;  3IU3 I;  5FO8 C;  2EHF A;  4C16 A;  4IGD A;  1G4F A;  1E5G A;  2CG6 A;  2JGX A;  1QO6 A;  1OK1 A;  3M7P A;  2YBY A;  1TPN A;  3IX0 A;  3EJH A;  1GHQ B;  4LOT A;  3RJ3 D;  3OXU D;  2W80 A;  4FXG G;  1OJW A;  3KXV A;  3INB C;  1CKL A;  4MUC A;  2G7I A;  2IZ3 A;  1GKN A;  1E88 A;  1OK9 A;  1NWV A;  1O9A A;  2RLP A;  1ELV A;  3R62 A;  3NFP I;  5HYU B;  4B2S A;  4ZH1 D;  3OP8 A;  1OK2 A; 
#chains in the Genus database with same CATH topology
 1ZJK A;  2XQW C;  2JRA A;  4N7E A;  2RLQ A;  1C1Z A;  2EC3 A;  3ERB A;  2XRB A;  1GKG A;  1VVD A;  1HCC A;  3ZLD A;  1TPG A;  2I2L A;  4F4O C;  4WJG 2;  4K12 A;  1HFI A;  4DJZ A;  1QUB A;  3MQL A;  1GPZ A;  4ONT D;  1H03 P;  2KMS A;  2QY0 A;  1PPQ A;  1MD8 A;  4AYD A;  4MSL A;  5HZP B;  1OK3 A;  4JHS A;  1E8B A;  2A55 A;  3GOV A;  4AYE A;  5DN4 A;  1VVC A;  4CSY A;  2XRD A;  4PO7 A;  5HYT B;  2XWB F;  1UOT P;  1FBR A;  1Q3X A;  1SS2 A;  5JPM G;  1Z92 B;  3OED C;  3TVJ A;  2MCZ A;  3ZLE A;  4LOS A;  2RL0 A;  4AYM A;  3WSX A;  2XWJ I;  1H04 P;  4YNX A;  3ZD2 A;  3ZRZ A;  1QGB A;  1H2P P;  2UWN A;  3CAL A;  1OJY A;  2CG7 A;  2B5I D;  2V8E A;  4J38 B;  2KRI A;  3KZJ A;  4B2R A;  1SRZ A;  2Y8R A;  1LY2 A;  2O39 C;  2IZ4 A;  3O8E B;  1G4G A;  3GXE A;  2W81 A;  1MD7 A;  4A5W B;  2BZM A;  1TPM A;  3L89 M;  2JGW A;  2RKZ A;  2Y8S A;  1H2Q P;  5HYP A;  2X2Z A;  2CKU A;  2RKY A;  2LOJ A;  2WII C;  2YRA A;  5I0Q B;  2ZYC A;  4PZ5 A;  1U5M A;  3T5O A;  3NJA A;  3WSY A;  1HFH A;  4AYI A;  1RLH A;  1OJV A;  3ZD1 A;  3SW0 X;  3FGR A;  2ERJ A;  3FGT A;  4KKD A;  2MCY A;  3IU3 I;  3F6K A;  5FO8 C;  3VWO A;  2EHF A;  4C16 A;  4IGD A;  1G4F A;  1E5G A;  2CG6 A;  2JGX A;  1QO6 A;  3K3T A;  1OK1 A;  3M7P A;  2YBY A;  1TPN A;  3IX0 A;  3EJH A;  4BWC A;  4YIZ A;  1GHQ B;  4LOT A;  3RJ3 D;  3OXU D;  2W80 A;  4APL A;  4FXG G;  1OJW A;  3KXV A;  3INB C;  1CKL A;  4MUC A;  2G7I A;  2IZ3 A;  3CI0 J;  5DN5 A;  1E88 A;  1OK9 A;  1GKN A;  1NWV A;  1O9A A;  2RLP A;  1ELV A;  2Y8T A;  3R62 A;  3NFP I;  5HYU B;  4B2S A;  4ZH1 D;  3OP8 A;  1OK2 A; 
#chains in the Genus database with same CATH homology
 1ZJK A;  2XQW C;  2JRA A;  2RLQ A;  1C1Z A;  2EC3 A;  3ERB A;  2XRB A;  1GKG A;  1VVD A;  1HCC A;  1TPG A;  4F4O C;  4WJG 2;  4K12 A;  1HFI A;  4DJZ A;  1QUB A;  3MQL A;  1GPZ A;  4ONT D;  1H03 P;  2KMS A;  2QY0 A;  1PPQ A;  1MD8 A;  4AYD A;  5HZP B;  1OK3 A;  4JHS A;  1E8B A;  2A55 A;  3GOV A;  4AYE A;  1VVC A;  4CSY A;  2XRD A;  5HYT B;  2XWB F;  1UOT P;  1FBR A;  1Q3X A;  1SS2 A;  5JPM G;  1Z92 B;  3OED C;  3TVJ A;  2MCZ A;  4LOS A;  2RL0 A;  4AYM A;  2XWJ I;  1H04 P;  4YNX A;  3ZD2 A;  3ZRZ A;  1QGB A;  1H2P P;  2UWN A;  3CAL A;  1OJY A;  2CG7 A;  2B5I D;  2V8E A;  4J38 B;  2KRI A;  3KZJ A;  4B2R A;  1SRZ A;  1LY2 A;  2O39 C;  2IZ4 A;  3O8E B;  1G4G A;  3GXE A;  2W81 A;  1MD7 A;  4A5W B;  2BZM A;  1TPM A;  3L89 M;  2JGW A;  2RKZ A;  1H2Q P;  5HYP A;  2CKU A;  2RKY A;  2LOJ A;  2WII C;  2YRA A;  5I0Q B;  4PZ5 A;  1U5M A;  3T5O A;  1HFH A;  4AYI A;  1OJV A;  3ZD1 A;  3SW0 X;  2ERJ A;  4KKD A;  2MCY A;  3IU3 I;  5FO8 C;  2EHF A;  4C16 A;  4IGD A;  1G4F A;  1E5G A;  2CG6 A;  2JGX A;  1QO6 A;  1OK1 A;  3M7P A;  2YBY A;  1TPN A;  3IX0 A;  3EJH A;  1GHQ B;  4LOT A;  3RJ3 D;  3OXU D;  2W80 A;  4FXG G;  1OJW A;  3KXV A;  3INB C;  1CKL A;  4MUC A;  2G7I A;  2IZ3 A;  1GKN A;  1E88 A;  1OK9 A;  1NWV A;  1O9A A;  2RLP A;  1ELV A;  3R62 A;  3NFP I;  5HYU B;  4B2S A;  4ZH1 D;  3OP8 A;  1OK2 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5HYPA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations