1C84A

Crystal structure of protein tyrosine phosphatase 1b complexed with 3-(oxalyl-amino)-naphthalene-2-carboxlic acid
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKTYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLDMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B)
publication title 2-(oxalylamino)-benzoic acid is a general, competitive inhibitor of protein-tyrosine phosphatases.
pubmed doi rcsb
source organism Homo sapiens
total genus 107
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-04-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1c84A00
4ZI4A 2HC1A 1OESA 5KA4A 2PA5A 4PYHA 2FJNA 3QCGA 1XXVA 4R0SA 4KYQA 3EZZA 1ONZA 3D1OA 4J51A 3I36A 1U25A 4Y14A 3LJ8A 2F6WA 3QCMA 3RGQA 5KADA 1T4JA 4H34A 4OHDA 4WU2A 1QZ0A 1LQFA 2CFVA 3ZV2A 4Z6BA 5BZZA 5K23A 3V0IA 1U26A 2PQ5A 2CJZA 2Q05A 4AZ1A 4RKKA 3GXGA 2CNHA 2P4DA 3ZM0A 3ZM1A 2CNGA 2QBSA 3I80A 4QUMA 2OZ5A 3RZ2A 2H03A 2IMGA 1PA1A 1L8KA 5I6VA 1Q6JA 3ZMPA 1MKPA 2HVLA 4MBBA 1G7FA 1ZC0A 3V0JA 1Q6PA 2GP0A 3D44A 1JLNA 4YR8B 3D42A 5KAAA 2H4KA 1ZCKA 5KA1A 3F41A 3EMUA 1G4WR 1PYNA 1GFYA 2I4HA 4KYRA 2ZN7A 1YTWA 1XXPA 2CMBA 3D1QA 2Y2FA 1WAXA 1RXDA 4ICZA 4YAAA 4GE2A 1T49A 3QKPA 3F99A 3QCBA 5IBSA 3O4TA 2CNFA 2P6XA 2Q47A 3RO1A 4NWFA 1WRMA 2CNEA 3OMHA 5K25A 3D9CA 5KA9A 2NTAA 4OHIA 2I6JA 2QBPA 3V0GA 4RH9A 2G59A 3U96A 2F6ZA 1XBOA 2J16B 5MMZB 1YZ4A 4NX8A 4OHEA 3MOZA 2I1YA 2I3UA 5AWXA 1KAKA 1OEOX 1QXKA 1ECVA 5K9VA 4OHHA 2FH7A 4PVGA 3D1HA 1PXHA 4GFVA 3BM8A 2RF6A 1FPRA 2OOQA 4RHGA 2YDUA 4GS0A 2VEUA 4B04A 3O5XA 4ZN5A 2CMAA 3S3EA 1G4US 2B4PA 3F81A 5KABA 3A5JA 2GWOA 2OUDA 3V0DA 4QAHA 1OHDA 4GRYA 2QEPA 3S3HA 1Q1MA 3BLTA 2QDPA 1OHCA 1PA9A 1YGUA 2HNQA 1NWLA 4WTYA 2VEWA 2A3KA 4I8NA 2F71A 2QBQA 4QBWA 1OEMX 2J16A 1I9SA 1Q6NA 5BUGA 1V3AA 1A5YA 1KAVA 2HY3A 3AWGA 4GFUA 3BRHA 1C83A 1PTUA 2CM8A 1Q6MA 4R30A 5BX1A 4GWFA 2QDCA 1NWEA 1OETA 4OHLA 4DGXA 2CM3A 4RDDA 3BLUA 5KA7A 2HC2A 3QCLA 1G1GA 1YWFA 3QCNA 2WGPA 4NNDA 1OEUA 1OHEA 2I6PA 1YFOA 3QKQA 2MBCA 1NZ7A 2PI7A 1ZZWA 1L8GA 2CMCA 4JMKA 2BZLA 3F9AA 2B49A 2PT0A 3SR9A 5EHPA 3ZM2A 2GJTA 5KA0A 2BGEA 4ERCA 2DXPA 2B3OA 5KACA 2VEXA 3QCCA 3I7ZA 1WCHA 4NYHA 2H4VA 1C86A 2BGDA 2CM7A 3OLRA 3AWEA 2HCMA 4IKCA 4KI9A 1U24A 2H02A 1Q6TA 5K9WA 1G7GA 1XM2A 1ONYA 3S4EA 3S3KA 1C88A 2QCTA 1P15A 3ZMQA 3QCHA 3M4UA 3CWEA 1FQ1A 2F70A 3RGOA 2AHSA 4H1OA 1EENA 1PTTA 2VEVA 4TVVA 2H04A 2I75A 2B4UA 3EU0A 2F6FA 4JMJA 3S4OA 3V0HA 3V0FA 1YTSA 2BIJA 1XRIA 1Q6SA 4NWGA 4D3PA 2F6YA 3MOWA 4D3QA 4DGPA 1RPMA 5EHRA 3MMJA 1NNYA 2I5XA 5KA8A 2B07A 5K24A 5KA2A 1ZCLA 1LARA 4JNBA 2VEYA 1SUGA 2NLKA 3B7OA 3F9BA 4ZRTA 1I57A 2I3RA 2F46A 2HXPA 2C46A 4WOHA 3PS5A 4JBCA 4BPCA 4WU3A 1YGRA 2NV5A 4RI4A 2QDMA 2R0BA 1FPZA 1VHRA 4HJPA 5J8RA 2ZMMA 3EB1A 1BZJA 3NMEA 2QCJA 1YTNA 5M43A 2I6MA 1M3GA 1G1HA 4QAPA 1T48A 2OC3A 1LYVA 1C84A 4HJQA 1J4XA 1GWZA 2H4GA 2B4OA 3QCKA 2A8BA 3O4SA 1C85A 2PSZA 5BZXA 2G6ZA 2AZRA 5IBMA 3V0EA 1PTYA 3SMEA 2CNIA 1JF7A 3GXHA 2I6OA 2Y96A 3H2XA 3N0AA 2M3VA 4Y2EA 1BZHA 4S0GA 1EEOA 3CM3A 2BV5A 1PTVA 2J17A 2HB1A 4RH5A 5KA3A 2F6TA 1YPTA 2CM2A 2QBRA 1G1FA 3QCJA 1YN9A 2HNPA 1R6HA 2SHPA 2JJDA 4R0TA 1X24A 3QCDA 3EAXA 5HDEA 2I4GA 1I9TA 3AWFA 4RI5A 5LXQB 3QCFA 1D5RA 2I6IA 2ESBA 4GE5A 4D3RA 1C87A 1OEVA 4QBEA 2F6VA 5K22A 2I4EA 3QCEA 3QCIA 2B4SA 1NO6A 2E0TA 1AAXA 4GRZA 2NT2A 2NT7A 3S3FA 2I42A 3A5KA 3O3LA 4GE6A 4HRFA 1PH0A 5GTJA 2NZ6A 3O4UA 4QUNA 1NL9A 3ZM3A 2FJMA 4BJOA 2C7SA 1BZCA 2PBNA
chains in the Genus database with same CATH superfamily
4ZI4A 2HC1A 1OESA 5KA4A 2PA5A 4PYHA 2FJNA 3QCGA 1XXVA 4R0SA 4KYQA 1GQYA 3EZZA 1ONZA 3D1OA 4J51A 3I36A 1U25A 4Y14A 3LJ8A 2F6WA 3QCMA 4ZIYA 3RGQA 5KADA 1T4JA 4H34A 1JBWA 4OHDA 4WU2A 3ZM6A 1QZ0A 4CVMA 1LQFA 4C12A 2CFVA 3ZV2A 4Z6BA 5BZZA 5K23A 3V0IA 1U26A 2PQ5A 2CJZA 2Q05A 4AZ1A 4RKKA 3GXGA 1JBVA 2CNHA 2P4DA 3ZM0A 3ZM1A 2CNGA 2QBSA 3I80A 4QUMA 2OZ5A 3RZ2A 2H03A 1GG4A 2IMGA 1PA1A 1L8KA 5I6VA 1GQQA 1Q6JA 3ZMPA 1W78A 1MKPA 2HVLA 4MBBA 1G7FA 1ZC0A 3V0JA 1Q6PA 2GP0A 3D44A 1JLNA 4YR8B 3D42A 5KAAA 2XPCA 2H4KA 1ZCKA 5KA1A 3UAGA 3F41A 3EMUA 1G4WR 1PYNA 1GFYA 4C13A 2I4HA 4KYRA 2GCAA 2ZN7A 1YTWA 1XXPA 2CMBA 3D1QA 2Y2FA 1WAXA 1RXDA 2VTEA 4ICZA 4YAAA 4GE2A 1T49A 2AM2A 3QKPA 3F99A 3QCBA 5IBSA 1UAGA 3O4TA 3MVNA 2CNFA 2P6XA 2Q47A 3RO1A 4NWFA 1WRMA 2CNEA 3OMHA 5K25A 2UAGA 3D9CA 5KA9A 2NTAA 4OHIA 2I6JA 2F00A 2QBPA 2VTDA 3V0GA 4RH9A 2G59A 3U96A 2F6ZA 1XBOA 2Y68A 2J16B 5MMZB 1YZ4A 2AM1A 4NX8A 3MOZA 4OHEA 4QDIA 2I1YA 2I3UA 5AWXA 1KAKA 1OEOX 1QXKA 1ECVA 4BUCA 5K9VA 4OHHA 2FH7A 4PVGA 3D1HA 1PXHA 4GFVA 3BM8A 2RF6A 1FPRA 2OOQA 4RHGA 2YDUA 1O5ZA 4GS0A 2VEUA 4B04A 3O5XA 4ZN5A 2CMAA 3S3EA 1G4US 2B4PA 3F81A 5A5FA 5KABA 3A5JA 2GWOA 2OUDA 1P3DA 3V0DA 4QAHA 1OHDA 4GRYA 2QEPA 3S3HA 1Q1MA 3BLTA 2QDPA 5A5EA 3ZM5A 1OHCA 1PA9A 1YGUA 2HNQA 1NWLA 4WTYA 2VEWA 2A3KA 4I8NA 2F71A 2QBQA 4QBWA 1OEMX 2J16A 1I9SA 1Q6NA 5BUGA 1V3AA 1A5YA 1KAVA 2HY3A 3AWGA 4CVLA 4GFUA 3BRHA 1C83A 1PTUA 2CM8A 1Q6MA 4R30A 5BX1A 4GWFA 2QDCA 1NWEA 1OETA 4OHLA 4DGXA 2CM3A 4RDDA 3BLUA 1EEHA 5KA7A 2HC2A 3QCLA 1G1GA 1YWFA 2UUOA 3QCNA 2WGPA 4NNDA 1OEUA 1OHEA 2I6PA 1YFOA 2XJAA 2MBCA 3QKQA 1NZ7A 2PI7A 1ZZWA 1L8GA 2CMCA 4JMKA 2BZLA 3F9AA 4HV4A 2B49A 2PT0A 3ZL8A 3SR9A 5EHPA 3ZM2A 2GJTA 5KA0A 2BGEA 4ERCA 2DXPA 2B3OA 3LK7A 1J6UA 5KACA 2VEXA 3QCCA 3I7ZA 1WCHA 4NYHA 2H4VA 1C86A 2Y66A 2BGDA 2CM7A 3OLRA 3AWEA 2HCMA 4IKCA 4KI9A 1U24A 2H02A 1W7KA 1Q6TA 5K9WA 1G7GA 1XM2A 1ONYA 3S4EA 3S3KA 1C88A 2QCTA 1P15A 2GC6A 3ZMQA 3QCHA 2Y1OA 3M4UA 3CWEA 1FQ1A 2F70A 3RGOA 2AHSA 4H1OA 1FGSA 1EENA 1PTTA 2VEVA 4TVVA 2H04A 2I75A 2B4UA 3EU0A 2F6FA 4JMJA 2GCBA 3S4OA 3V0HA 3V0FA 1YTSA 2BIJA 1XRIA 1Q6SA 4NWGA 4D3PA 2UUPA 2F6YA 3MOWA 4D3QA 1E8CA 4DGPA 1RPMA 5EHRA 3MMJA 1NNYA 2I5XA 5KA8A 2B07A 5K24A 5KA2A 2JFGA 1ZCLA 1LARA 4JNBA 2JFHA 2VEYA 1SUGA 2NLKA 3B7OA 3F9BA 4ZRTA 1I57A 2I3RA 3QCZA 2F46A 1E0DA 2HXPA 2C46A 4WOHA 3PS5A 4JBCA 4BPCA 4WU3A 1YGRA 2NV5A 4RI4A 2QDMA 2R0BA 1FPZA 1VHRA 4HJPA 5J8RA 2ZMMA 3EB1A 1BZJA 3NMEA 2QCJA 1YTNA 5M43A 2I6MA 1M3GA 1G1HA 4QAPA 1T48A 2OC3A 2VORA 1LYVA 1C84A 4HJQA 1J4XA 1GWZA 2H4GA 2B4OA 3QCKA 2A8BA 3NRSA 3O4SA 1C85A 2PSZA 5BZXA 2G6ZA 2AZRA 5IBMA 3V0EA 1PTYA 3SMEA 2WJPA 2CNIA 1JF7A 3GXHA 2WTZA 2I6OA 2VOSA 2Y96A 3H2XA 3N0AA 2M3VA 4Y2EA 1BZHA 4S0GA 1EEOA 4CVKA 3CM3A 2BV5A 1PTVA 2J17A 2HB1A 4BUBA 4RH5A 5KA3A 1P31A 2F6TA 1YPTA 2CM2A 2QBRA 1G1FA 3QCJA 1YN9A 2HNPA 1R6HA 2SHPA 2JJDA 4R0TA 1X24A 3QCDA 3EAXA 5HDEA 2I4GA 1I9TA 3AWFA 3HN7A 4RI5A 5LXQB 3QCFA 1D5RA 2I6IA 2ESBA 4GE5A 2JFFA 4D3RA 1C87A 1OEVA 2X5OA 2GC5A 4QBEA 4UAGA 2F6VA 5K22A 2I4EA 3QCEA 4QF5A 3QCIA 2B4SA 1NO6A 3N2AA 2E0TA 1AAXA 4GRZA 2NT2A 2NT7A 3S3FA 2I42A 3A5KA 3O3LA 4GE6A 4HRFA 1PH0A 5GTJA 2NZ6A 3O4UA 4QUNA 3PYZA 1NL9A 3ZM3A 2FJMA 2Y67A 4BJOA 2C7SA 1BZCA 2PBNA
chains in the Genus database with same CATH topology
4ZI4A 2HC1A 1OESA 5KA4A 2PA5A 4PYHA 2FJNA 3QCGA 1XXVA 4R0SA 4KYQA 3EZZA 1ONZA 3D1OA 4J51A 3I36A 1U25A 4Y14A 3LJ8A 2F6WA 3QCMA 3RGQA 5KADA 1T4JA 4H34A 4OHDA 4WU2A 1QZ0A 1LQFA 2CFVA 3ZV2A 4Z6BA 5BZZA 5K23A 3V0IA 1U26A 2PQ5A 2CJZA 2Q05A 4AZ1A 4RKKA 3GXGA 2CNHA 2P4DA 3ZM0A 3ZM1A 2CNGA 2QBSA 3I80A 4QUMA 2OZ5A 3RZ2A 2H03A 2IMGA 1PA1A 1L8KA 5I6VA 1Q6JA 3ZMPA 1MKPA 2HVLA 4MBBA 1G7FA 1ZC0A 3V0JA 1Q6PA 2GP0A 3D44A 1JLNA 4YR8B 3D42A 5KAAA 2H4KA 1ZCKA 5KA1A 3F41A 3EMUA 1G4WR 1PYNA 1GFYA 2I4HA 4KYRA 2ZN7A 1YTWA 1XXPA 2CMBA 3D1QA 2Y2FA 1WAXA 1RXDA 4ICZA 4YAAA 4GE2A 1T49A 3QKPA 3F99A 3QCBA 5IBSA 3O4TA 2CNFA 2P6XA 2Q47A 3RO1A 4NWFA 1WRMA 2CNEA 3OMHA 5K25A 3D9CA 5KA9A 2NTAA 4OHIA 2I6JA 2QBPA 3V0GA 4RH9A 2G59A 3U96A 2F6ZA 1XBOA 2J16B 5MMZB 1YZ4A 4NX8A 4OHEA 3MOZA 2I1YA 2I3UA 5AWXA 1KAKA 1OEOX 1QXKA 1ECVA 5K9VA 4OHHA 2FH7A 4PVGA 3D1HA 1PXHA 4GFVA 3BM8A 2RF6A 1FPRA 2OOQA 4RHGA 2YDUA 4GS0A 2VEUA 4B04A 3O5XA 4ZN5A 2CMAA 3S3EA 1G4US 2B4PA 3F81A 5KABA 3A5JA 2GWOA 2OUDA 3V0DA 4QAHA 1OHDA 4GRYA 2QEPA 3S3HA 1Q1MA 3BLTA 2QDPA 1OHCA 1PA9A 1YGUA 2HNQA 1NWLA 4WTYA 2VEWA 2A3KA 4I8NA 2F71A 2QBQA 4QBWA 1OEMX 2J16A 1I9SA 1Q6NA 5BUGA 1V3AA 1A5YA 1KAVA 2HY3A 3AWGA 4GFUA 3BRHA 1C83A 1PTUA 2CM8A 1Q6MA 4R30A 5BX1A 4GWFA 2QDCA 1NWEA 1OETA 4OHLA 4DGXA 2CM3A 4RDDA 3BLUA 5KA7A 2HC2A 3QCLA 1G1GA 1YWFA 3QCNA 2WGPA 4NNDA 1OEUA 1OHEA 2I6PA 1YFOA 3QKQA 2MBCA 1NZ7A 2PI7A 1ZZWA 1L8GA 2CMCA 4JMKA 2BZLA 3F9AA 2B49A 2PT0A 3SR9A 5EHPA 3ZM2A 2GJTA 5KA0A 2BGEA 4ERCA 2DXPA 2B3OA 5KACA 2VEXA 3QCCA 3I7ZA 1WCHA 4NYHA 2H4VA 1C86A 2BGDA 2CM7A 3OLRA 3AWEA 2HCMA 4IKCA 4KI9A 1U24A 2H02A 1Q6TA 5K9WA 1G7GA 1XM2A 1ONYA 3S4EA 3S3KA 1C88A 2QCTA 1P15A 3ZMQA 3QCHA 3M4UA 3CWEA 1FQ1A 2F70A 3RGOA 2AHSA 4H1OA 1EENA 1PTTA 2VEVA 4TVVA 2H04A 2I75A 2B4UA 3EU0A 2F6FA 4JMJA 3S4OA 3V0HA 3V0FA 1YTSA 2BIJA 1XRIA 1Q6SA 4NWGA 4D3PA 2F6YA 3MOWA 4D3QA 4DGPA 1RPMA 5EHRA 3MMJA 1NNYA 2I5XA 5KA8A 2B07A 5K24A 5KA2A 1ZCLA 1LARA 4JNBA 2VEYA 1SUGA 2NLKA 3B7OA 3F9BA 4ZRTA 1I57A 2I3RA 2F46A 2HXPA 2C46A 4WOHA 3PS5A 4JBCA 4BPCA 4WU3A 1YGRA 2NV5A 4RI4A 2QDMA 2R0BA 1FPZA 1VHRA 4HJPA 5J8RA 2ZMMA 3EB1A 1BZJA 3NMEA 2QCJA 1YTNA 5M43A 2I6MA 1M3GA 1G1HA 4QAPA 1T48A 2OC3A 1LYVA 1C84A 4HJQA 1J4XA 1GWZA 2H4GA 2B4OA 3QCKA 2A8BA 3O4SA 1C85A 2PSZA 5BZXA 2G6ZA 2AZRA 5IBMA 3V0EA 1PTYA 3SMEA 2CNIA 1JF7A 3GXHA 2I6OA 2Y96A 3H2XA 3N0AA 2M3VA 4Y2EA 1BZHA 4S0GA 1EEOA 3CM3A 2BV5A 1PTVA 2J17A 2HB1A 4RH5A 5KA3A 2F6TA 1YPTA 2CM2A 2QBRA 1G1FA 3QCJA 1YN9A 2HNPA 1R6HA 2SHPA 2JJDA 4R0TA 1X24A 3QCDA 3EAXA 5HDEA 2I4GA 1I9TA 3AWFA 4RI5A 5LXQB 3QCFA 1D5RA 2I6IA 2ESBA 4GE5A 4D3RA 1C87A 1OEVA 4QBEA 2F6VA 5K22A 2I4EA 3QCEA 3QCIA 2B4SA 1NO6A 2E0TA 1AAXA 4GRZA 2NT2A 2NT7A 3S3FA 2I42A 3A5KA 3O3LA 4GE6A 4HRFA 1PH0A 5GTJA 2NZ6A 3O4UA 4QUNA 1NL9A 3ZM3A 2FJMA 4BJOA 2C7SA 1BZCA 2PBNA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4ZI4 A;  2HC1 A;  1OES A;  5KA4 A;  2PA5 A;  4PYH A;  2FJN A;  3QCG A;  1XXV A;  4R0S A;  4KYQ A;  3EZZ A;  1ONZ A;  3D1O A;  4J51 A;  3I36 A;  1U25 A;  4Y14 A;  3LJ8 A;  2F6W A;  3QCM A;  3RGQ A;  5KAD A;  1T4J A;  4H34 A;  4OHD A;  4WU2 A;  1QZ0 A;  1LQF A;  2CFV A;  3ZV2 A;  4Z6B A;  5BZZ A;  5K23 A;  3V0I A;  1U26 A;  2PQ5 A;  2CJZ A;  2Q05 A;  4AZ1 A;  4RKK A;  3GXG A;  2CNH A;  2P4D A;  3ZM0 A;  3ZM1 A;  2CNG A;  2QBS A;  3I80 A;  4QUM A;  2OZ5 A;  3RZ2 A;  2H03 A;  2IMG A;  1PA1 A;  1L8K A;  5I6V A;  1Q6J A;  3ZMP A;  1MKP A;  2HVL A;  4MBB A;  1G7F A;  1ZC0 A;  3V0J A;  1Q6P A;  2GP0 A;  3D44 A;  1JLN A;  4YR8 B;  3D42 A;  5KAA A;  2H4K A;  1ZCK A;  5KA1 A;  3F41 A;  3EMU A;  1G4W R;  1PYN A;  1GFY A;  2I4H A;  4KYR A;  2ZN7 A;  1YTW A;  1XXP A;  2CMB A;  3D1Q A;  2Y2F A;  1WAX A;  1RXD A;  4ICZ A;  4YAA A;  4GE2 A;  1T49 A;  3QKP A;  3F99 A;  3QCB A;  5IBS A;  3O4T A;  2CNF A;  2P6X A;  2Q47 A;  3RO1 A;  4NWF A;  1WRM A;  2CNE A;  3OMH A;  5K25 A;  3D9C A;  5KA9 A;  2NTA A;  4OHI A;  2I6J A;  2QBP A;  3V0G A;  4RH9 A;  2G59 A;  3U96 A;  2F6Z A;  1XBO A;  2J16 B;  5MMZ B;  1YZ4 A;  4NX8 A;  4OHE A;  3MOZ A;  2I1Y A;  2I3U A;  5AWX A;  1KAK A;  1OEO X;  1QXK A;  1ECV A;  5K9V A;  4OHH A;  2FH7 A;  4PVG A;  3D1H A;  1PXH A;  4GFV A;  3BM8 A;  2RF6 A;  1FPR A;  2OOQ A;  4RHG A;  2YDU A;  4GS0 A;  2VEU A;  4B04 A;  3O5X A;  4ZN5 A;  2CMA A;  3S3E A;  1G4U S;  2B4P A;  3F81 A;  5KAB A;  3A5J A;  2GWO A;  2OUD A;  3V0D A;  4QAH A;  1OHD A;  4GRY A;  2QEP A;  3S3H A;  1Q1M A;  3BLT A;  2QDP A;  1OHC A;  1PA9 A;  1YGU A;  2HNQ A;  1NWL A;  4WTY A;  2VEW A;  2A3K A;  4I8N A;  2F71 A;  2QBQ A;  4QBW A;  1OEM X;  2J16 A;  1I9S A;  1Q6N A;  5BUG A;  1V3A A;  1A5Y A;  1KAV A;  2HY3 A;  3AWG A;  4GFU A;  3BRH A;  1C83 A;  1PTU A;  2CM8 A;  1Q6M A;  4R30 A;  5BX1 A;  4GWF A;  2QDC A;  1NWE A;  1OET A;  4OHL A;  4DGX A;  2CM3 A;  4RDD A;  3BLU A;  5KA7 A;  2HC2 A;  3QCL A;  1G1G A;  1YWF A;  3QCN A;  2WGP A;  4NND A;  1OEU A;  1OHE A;  2I6P A;  1YFO A;  3QKQ A;  2MBC A;  1NZ7 A;  2PI7 A;  1ZZW A;  1L8G A;  2CMC A;  4JMK A;  2BZL A;  3F9A A;  2B49 A;  2PT0 A;  3SR9 A;  5EHP A;  3ZM2 A;  2GJT A;  5KA0 A;  2BGE A;  4ERC A;  2DXP A;  2B3O A;  5KAC A;  2VEX A;  3QCC A;  3I7Z A;  1WCH A;  4NYH A;  2H4V A;  1C86 A;  2BGD A;  2CM7 A;  3OLR A;  3AWE A;  2HCM A;  4IKC A;  4KI9 A;  1U24 A;  2H02 A;  1Q6T A;  5K9W A;  1G7G A;  1XM2 A;  1ONY A;  3S4E A;  3S3K A;  1C88 A;  2QCT A;  1P15 A;  3ZMQ A;  3QCH A;  3M4U A;  3CWE A;  1FQ1 A;  2F70 A;  3RGO A;  2AHS A;  4H1O A;  1EEN A;  1PTT A;  2VEV A;  4TVV A;  2H04 A;  2I75 A;  2B4U A;  3EU0 A;  2F6F A;  4JMJ A;  3S4O A;  3V0H A;  3V0F A;  1YTS A;  2BIJ A;  1XRI A;  1Q6S A;  4NWG A;  4D3P A;  2F6Y A;  3MOW A;  4D3Q A;  4DGP A;  1RPM A;  5EHR A;  3MMJ A;  1NNY A;  2I5X A;  5KA8 A;  2B07 A;  5K24 A;  5KA2 A;  1ZCL A;  1LAR A;  4JNB A;  2VEY A;  1SUG A;  2NLK A;  3B7O A;  3F9B A;  4ZRT A;  1I57 A;  2I3R A;  2F46 A;  2HXP A;  2C46 A;  4WOH A;  3PS5 A;  4JBC A;  4BPC A;  4WU3 A;  1YGR A;  2NV5 A;  4RI4 A;  2QDM A;  2R0B A;  1FPZ A;  1VHR A;  4HJP A;  5J8R A;  2ZMM A;  3EB1 A;  1BZJ A;  3NME A;  2QCJ A;  1YTN A;  5M43 A;  2I6M A;  1M3G A;  1G1H A;  4QAP A;  1T48 A;  2OC3 A;  1LYV A;  1C84 A;  4HJQ A;  1J4X A;  1GWZ A;  2H4G A;  2B4O A;  3QCK A;  2A8B A;  3O4S A;  1C85 A;  2PSZ A;  5BZX A;  2G6Z A;  2AZR A;  5IBM A;  3V0E A;  1PTY A;  3SME A;  2CNI A;  1JF7 A;  3GXH A;  2I6O A;  2Y96 A;  3H2X A;  3N0A A;  2M3V A;  4Y2E A;  1BZH A;  4S0G A;  1EEO A;  3CM3 A;  2BV5 A;  1PTV A;  2J17 A;  2HB1 A;  4RH5 A;  5KA3 A;  2F6T A;  1YPT A;  2CM2 A;  2QBR A;  1G1F A;  3QCJ A;  1YN9 A;  2HNP A;  1R6H A;  2SHP A;  2JJD A;  4R0T A;  1X24 A;  3QCD A;  3EAX A;  5HDE A;  2I4G A;  1I9T A;  3AWF A;  4RI5 A;  5LXQ B;  3QCF A;  1D5R A;  2I6I A;  2ESB A;  4GE5 A;  4D3R A;  1C87 A;  1OEV A;  4QBE A;  2F6V A;  5K22 A;  2I4E A;  3QCE A;  3QCI A;  2B4S A;  1NO6 A;  2E0T A;  1AAX A;  4GRZ A;  2NT2 A;  2NT7 A;  3S3F A;  2I42 A;  3A5K A;  3O3L A;  4GE6 A;  4HRF A;  1PH0 A;  5GTJ A;  2NZ6 A;  3O4U A;  4QUN A;  1NL9 A;  3ZM3 A;  2FJM A;  4BJO A;  2C7S A;  1BZC A;  2PBN A; 
#chains in the Genus database with same CATH topology
 4ZI4 A;  2HC1 A;  1OES A;  5KA4 A;  2PA5 A;  4PYH A;  2FJN A;  3QCG A;  1XXV A;  4R0S A;  4KYQ A;  1GQY A;  3EZZ A;  1ONZ A;  3D1O A;  4J51 A;  3I36 A;  1U25 A;  4Y14 A;  3LJ8 A;  2F6W A;  3QCM A;  4ZIY A;  3RGQ A;  5KAD A;  1T4J A;  4H34 A;  1JBW A;  4OHD A;  4WU2 A;  3ZM6 A;  1QZ0 A;  4CVM A;  1LQF A;  4C12 A;  2CFV A;  3ZV2 A;  4Z6B A;  5BZZ A;  5K23 A;  3V0I A;  1U26 A;  2PQ5 A;  2CJZ A;  2Q05 A;  4AZ1 A;  4RKK A;  3GXG A;  1JBV A;  2CNH A;  2P4D A;  3ZM0 A;  3ZM1 A;  2CNG A;  2QBS A;  3I80 A;  4QUM A;  2OZ5 A;  3RZ2 A;  2H03 A;  1GG4 A;  2IMG A;  1PA1 A;  1L8K A;  5I6V A;  1GQQ A;  1Q6J A;  3ZMP A;  1W78 A;  1MKP A;  2HVL A;  4MBB A;  1G7F A;  1ZC0 A;  3V0J A;  1Q6P A;  2GP0 A;  3D44 A;  1JLN A;  4YR8 B;  3D42 A;  5KAA A;  2XPC A;  2H4K A;  1ZCK A;  5KA1 A;  3UAG A;  3F41 A;  3EMU A;  1G4W R;  1PYN A;  1GFY A;  4C13 A;  2I4H A;  4KYR A;  2GCA A;  2ZN7 A;  1YTW A;  1XXP A;  2CMB A;  3D1Q A;  2Y2F A;  1WAX A;  1RXD A;  2VTE A;  4ICZ A;  4YAA A;  4GE2 A;  1T49 A;  2AM2 A;  3QKP A;  3F99 A;  3QCB A;  5IBS A;  1UAG A;  3O4T A;  3MVN A;  2CNF A;  2P6X A;  2Q47 A;  3RO1 A;  4NWF A;  1WRM A;  2CNE A;  3OMH A;  5K25 A;  2UAG A;  3D9C A;  5KA9 A;  2NTA A;  4OHI A;  2I6J A;  2F00 A;  2QBP A;  2VTD A;  3V0G A;  4RH9 A;  2G59 A;  3U96 A;  2F6Z A;  1XBO A;  2Y68 A;  2J16 B;  5MMZ B;  1YZ4 A;  2AM1 A;  4NX8 A;  3MOZ A;  4OHE A;  4QDI A;  2I1Y A;  2I3U A;  5AWX A;  1KAK A;  1OEO X;  1QXK A;  1ECV A;  4BUC A;  5K9V A;  4OHH A;  2FH7 A;  4PVG A;  3D1H A;  1PXH A;  4GFV A;  3BM8 A;  2RF6 A;  1FPR A;  2OOQ A;  4RHG A;  2YDU A;  1O5Z A;  4GS0 A;  2VEU A;  4B04 A;  3O5X A;  4ZN5 A;  2CMA A;  3S3E A;  1G4U S;  2B4P A;  3F81 A;  5A5F A;  5KAB A;  3A5J A;  2GWO A;  2OUD A;  1P3D A;  3V0D A;  4QAH A;  1OHD A;  4GRY A;  2QEP A;  3S3H A;  1Q1M A;  3BLT A;  2QDP A;  5A5E A;  3ZM5 A;  1OHC A;  1PA9 A;  1YGU A;  2HNQ A;  1NWL A;  4WTY A;  2VEW A;  2A3K A;  4I8N A;  2F71 A;  2QBQ A;  4QBW A;  1OEM X;  2J16 A;  1I9S A;  1Q6N A;  5BUG A;  1V3A A;  1A5Y A;  1KAV A;  2HY3 A;  3AWG A;  4CVL A;  4GFU A;  3BRH A;  1C83 A;  1PTU A;  2CM8 A;  1Q6M A;  4R30 A;  5BX1 A;  4GWF A;  2QDC A;  1NWE A;  1OET A;  4OHL A;  4DGX A;  2CM3 A;  4RDD A;  3BLU A;  1EEH A;  5KA7 A;  2HC2 A;  3QCL A;  1G1G A;  1YWF A;  2UUO A;  3QCN A;  2WGP A;  4NND A;  1OEU A;  1OHE A;  2I6P A;  1YFO A;  2XJA A;  2MBC A;  3QKQ A;  1NZ7 A;  2PI7 A;  1ZZW A;  1L8G A;  2CMC A;  4JMK A;  2BZL A;  3F9A A;  4HV4 A;  2B49 A;  2PT0 A;  3ZL8 A;  3SR9 A;  5EHP A;  3ZM2 A;  2GJT A;  5KA0 A;  2BGE A;  4ERC A;  2DXP A;  2B3O A;  3LK7 A;  1J6U A;  5KAC A;  2VEX A;  3QCC A;  3I7Z A;  1WCH A;  4NYH A;  2H4V A;  1C86 A;  2Y66 A;  2BGD A;  2CM7 A;  3OLR A;  3AWE A;  2HCM A;  4IKC A;  4KI9 A;  1U24 A;  2H02 A;  1W7K A;  1Q6T A;  5K9W A;  1G7G A;  1XM2 A;  1ONY A;  3S4E A;  3S3K A;  1C88 A;  2QCT A;  1P15 A;  2GC6 A;  3ZMQ A;  3QCH A;  2Y1O A;  3M4U A;  3CWE A;  1FQ1 A;  2F70 A;  3RGO A;  2AHS A;  4H1O A;  1FGS A;  1EEN A;  1PTT A;  2VEV A;  4TVV A;  2H04 A;  2I75 A;  2B4U A;  3EU0 A;  2F6F A;  4JMJ A;  2GCB A;  3S4O A;  3V0H A;  3V0F A;  1YTS A;  2BIJ A;  1XRI A;  1Q6S A;  4NWG A;  4D3P A;  2UUP A;  2F6Y A;  3MOW A;  4D3Q A;  1E8C A;  4DGP A;  1RPM A;  5EHR A;  3MMJ A;  1NNY A;  2I5X A;  5KA8 A;  2B07 A;  5K24 A;  5KA2 A;  2JFG A;  1ZCL A;  1LAR A;  4JNB A;  2JFH A;  2VEY A;  1SUG A;  2NLK A;  3B7O A;  3F9B A;  4ZRT A;  1I57 A;  2I3R A;  3QCZ A;  2F46 A;  1E0D A;  2HXP A;  2C46 A;  4WOH A;  3PS5 A;  4JBC A;  4BPC A;  4WU3 A;  1YGR A;  2NV5 A;  4RI4 A;  2QDM A;  2R0B A;  1FPZ A;  1VHR A;  4HJP A;  5J8R A;  2ZMM A;  3EB1 A;  1BZJ A;  3NME A;  2QCJ A;  1YTN A;  5M43 A;  2I6M A;  1M3G A;  1G1H A;  4QAP A;  1T48 A;  2OC3 A;  2VOR A;  1LYV A;  1C84 A;  4HJQ A;  1J4X A;  1GWZ A;  2H4G A;  2B4O A;  3QCK A;  2A8B A;  3NRS A;  3O4S A;  1C85 A;  2PSZ A;  5BZX A;  2G6Z A;  2AZR A;  5IBM A;  3V0E A;  1PTY A;  3SME A;  2WJP A;  2CNI A;  1JF7 A;  3GXH A;  2WTZ A;  2I6O A;  2VOS A;  2Y96 A;  3H2X A;  3N0A A;  2M3V A;  4Y2E A;  1BZH A;  4S0G A;  1EEO A;  4CVK A;  3CM3 A;  2BV5 A;  1PTV A;  2J17 A;  2HB1 A;  4BUB A;  4RH5 A;  5KA3 A;  1P31 A;  2F6T A;  1YPT A;  2CM2 A;  2QBR A;  1G1F A;  3QCJ A;  1YN9 A;  2HNP A;  1R6H A;  2SHP A;  2JJD A;  4R0T A;  1X24 A;  3QCD A;  3EAX A;  5HDE A;  2I4G A;  1I9T A;  3AWF A;  3HN7 A;  4RI5 A;  5LXQ B;  3QCF A;  1D5R A;  2I6I A;  2ESB A;  4GE5 A;  2JFF A;  4D3R A;  1C87 A;  1OEV A;  2X5O A;  2GC5 A;  4QBE A;  4UAG A;  2F6V A;  5K22 A;  2I4E A;  3QCE A;  4QF5 A;  3QCI A;  2B4S A;  1NO6 A;  3N2A A;  2E0T A;  1AAX A;  4GRZ A;  2NT2 A;  2NT7 A;  3S3F A;  2I42 A;  3A5K A;  3O3L A;  4GE6 A;  4HRF A;  1PH0 A;  5GTJ A;  2NZ6 A;  3O4U A;  4QUN A;  3PYZ A;  1NL9 A;  3ZM3 A;  2FJM A;  2Y67 A;  4BJO A;  2C7S A;  1BZC A;  2PBN A; 
#chains in the Genus database with same CATH homology
 4ZI4 A;  2HC1 A;  1OES A;  5KA4 A;  2PA5 A;  4PYH A;  2FJN A;  3QCG A;  1XXV A;  4R0S A;  4KYQ A;  3EZZ A;  1ONZ A;  3D1O A;  4J51 A;  3I36 A;  1U25 A;  4Y14 A;  3LJ8 A;  2F6W A;  3QCM A;  3RGQ A;  5KAD A;  1T4J A;  4H34 A;  4OHD A;  4WU2 A;  1QZ0 A;  1LQF A;  2CFV A;  3ZV2 A;  4Z6B A;  5BZZ A;  5K23 A;  3V0I A;  1U26 A;  2PQ5 A;  2CJZ A;  2Q05 A;  4AZ1 A;  4RKK A;  3GXG A;  2CNH A;  2P4D A;  3ZM0 A;  3ZM1 A;  2CNG A;  2QBS A;  3I80 A;  4QUM A;  2OZ5 A;  3RZ2 A;  2H03 A;  2IMG A;  1PA1 A;  1L8K A;  5I6V A;  1Q6J A;  3ZMP A;  1MKP A;  2HVL A;  4MBB A;  1G7F A;  1ZC0 A;  3V0J A;  1Q6P A;  2GP0 A;  3D44 A;  1JLN A;  4YR8 B;  3D42 A;  5KAA A;  2H4K A;  1ZCK A;  5KA1 A;  3F41 A;  3EMU A;  1G4W R;  1PYN A;  1GFY A;  2I4H A;  4KYR A;  2ZN7 A;  1YTW A;  1XXP A;  2CMB A;  3D1Q A;  2Y2F A;  1WAX A;  1RXD A;  4ICZ A;  4YAA A;  4GE2 A;  1T49 A;  3QKP A;  3F99 A;  3QCB A;  5IBS A;  3O4T A;  2CNF A;  2P6X A;  2Q47 A;  3RO1 A;  4NWF A;  1WRM A;  2CNE A;  3OMH A;  5K25 A;  3D9C A;  5KA9 A;  2NTA A;  4OHI A;  2I6J A;  2QBP A;  3V0G A;  4RH9 A;  2G59 A;  3U96 A;  2F6Z A;  1XBO A;  2J16 B;  5MMZ B;  1YZ4 A;  4NX8 A;  4OHE A;  3MOZ A;  2I1Y A;  2I3U A;  5AWX A;  1KAK A;  1OEO X;  1QXK A;  1ECV A;  5K9V A;  4OHH A;  2FH7 A;  4PVG A;  3D1H A;  1PXH A;  4GFV A;  3BM8 A;  2RF6 A;  1FPR A;  2OOQ A;  4RHG A;  2YDU A;  4GS0 A;  2VEU A;  4B04 A;  3O5X A;  4ZN5 A;  2CMA A;  3S3E A;  1G4U S;  2B4P A;  3F81 A;  5KAB A;  3A5J A;  2GWO A;  2OUD A;  3V0D A;  4QAH A;  1OHD A;  4GRY A;  2QEP A;  3S3H A;  1Q1M A;  3BLT A;  2QDP A;  1OHC A;  1PA9 A;  1YGU A;  2HNQ A;  1NWL A;  4WTY A;  2VEW A;  2A3K A;  4I8N A;  2F71 A;  2QBQ A;  4QBW A;  1OEM X;  2J16 A;  1I9S A;  1Q6N A;  5BUG A;  1V3A A;  1A5Y A;  1KAV A;  2HY3 A;  3AWG A;  4GFU A;  3BRH A;  1C83 A;  1PTU A;  2CM8 A;  1Q6M A;  4R30 A;  5BX1 A;  4GWF A;  2QDC A;  1NWE A;  1OET A;  4OHL A;  4DGX A;  2CM3 A;  4RDD A;  3BLU A;  5KA7 A;  2HC2 A;  3QCL A;  1G1G A;  1YWF A;  3QCN A;  2WGP A;  4NND A;  1OEU A;  1OHE A;  2I6P A;  1YFO A;  3QKQ A;  2MBC A;  1NZ7 A;  2PI7 A;  1ZZW A;  1L8G A;  2CMC A;  4JMK A;  2BZL A;  3F9A A;  2B49 A;  2PT0 A;  3SR9 A;  5EHP A;  3ZM2 A;  2GJT A;  5KA0 A;  2BGE A;  4ERC A;  2DXP A;  2B3O A;  5KAC A;  2VEX A;  3QCC A;  3I7Z A;  1WCH A;  4NYH A;  2H4V A;  1C86 A;  2BGD A;  2CM7 A;  3OLR A;  3AWE A;  2HCM A;  4IKC A;  4KI9 A;  1U24 A;  2H02 A;  1Q6T A;  5K9W A;  1G7G A;  1XM2 A;  1ONY A;  3S4E A;  3S3K A;  1C88 A;  2QCT A;  1P15 A;  3ZMQ A;  3QCH A;  3M4U A;  3CWE A;  1FQ1 A;  2F70 A;  3RGO A;  2AHS A;  4H1O A;  1EEN A;  1PTT A;  2VEV A;  4TVV A;  2H04 A;  2I75 A;  2B4U A;  3EU0 A;  2F6F A;  4JMJ A;  3S4O A;  3V0H A;  3V0F A;  1YTS A;  2BIJ A;  1XRI A;  1Q6S A;  4NWG A;  4D3P A;  2F6Y A;  3MOW A;  4D3Q A;  4DGP A;  1RPM A;  5EHR A;  3MMJ A;  1NNY A;  2I5X A;  5KA8 A;  2B07 A;  5K24 A;  5KA2 A;  1ZCL A;  1LAR A;  4JNB A;  2VEY A;  1SUG A;  2NLK A;  3B7O A;  3F9B A;  4ZRT A;  1I57 A;  2I3R A;  2F46 A;  2HXP A;  2C46 A;  4WOH A;  3PS5 A;  4JBC A;  4BPC A;  4WU3 A;  1YGR A;  2NV5 A;  4RI4 A;  2QDM A;  2R0B A;  1FPZ A;  1VHR A;  4HJP A;  5J8R A;  2ZMM A;  3EB1 A;  1BZJ A;  3NME A;  2QCJ A;  1YTN A;  5M43 A;  2I6M A;  1M3G A;  1G1H A;  4QAP A;  1T48 A;  2OC3 A;  1LYV A;  1C84 A;  4HJQ A;  1J4X A;  1GWZ A;  2H4G A;  2B4O A;  3QCK A;  2A8B A;  3O4S A;  1C85 A;  2PSZ A;  5BZX A;  2G6Z A;  2AZR A;  5IBM A;  3V0E A;  1PTY A;  3SME A;  2CNI A;  1JF7 A;  3GXH A;  2I6O A;  2Y96 A;  3H2X A;  3N0A A;  2M3V A;  4Y2E A;  1BZH A;  4S0G A;  1EEO A;  3CM3 A;  2BV5 A;  1PTV A;  2J17 A;  2HB1 A;  4RH5 A;  5KA3 A;  2F6T A;  1YPT A;  2CM2 A;  2QBR A;  1G1F A;  3QCJ A;  1YN9 A;  2HNP A;  1R6H A;  2SHP A;  2JJD A;  4R0T A;  1X24 A;  3QCD A;  3EAX A;  5HDE A;  2I4G A;  1I9T A;  3AWF A;  4RI5 A;  5LXQ B;  3QCF A;  1D5R A;  2I6I A;  2ESB A;  4GE5 A;  4D3R A;  1C87 A;  1OEV A;  4QBE A;  2F6V A;  5K22 A;  2I4E A;  3QCE A;  3QCI A;  2B4S A;  1NO6 A;  2E0T A;  1AAX A;  4GRZ A;  2NT2 A;  2NT7 A;  3S3F A;  2I42 A;  3A5K A;  3O3L A;  4GE6 A;  4HRF A;  1PH0 A;  5GTJ A;  2NZ6 A;  3O4U A;  4QUN A;  1NL9 A;  3ZM3 A;  2FJM A;  4BJO A;  2C7S A;  1BZC A;  2PBN A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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