3EAXA

Crystal structure ptp1b complex with small molecule compound lzp-6
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
282
structure length
282
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 95
structure length 282
sequence length 282
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2008-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3eaxA00
1NO6A 4GS0A 2QBQA 1GFYA 2FJMA 2DXPA 3V0JA 3ZM3A 3QCGA 4ZI4A 2WGPA 4ICZA 3D9CA 2NZ6A 2VEYA 2HNPA 1G1FA 1VHRA 1AAXA 1KAKA 1L8GA 2OOQA 3MMJA 4RI5A 2ZMMA 1QXKA 3A5JA 1PXHA 3MOWA 1T4JA 4GRZA 5AWXA 2B49A 4QAHA 2B3OA 2I3UA 2B4SA 4J51A 1G4US 3V0IA 5KA9A 2I6PA 1LQFA 1U25A 4GFVA 2NT2A 1C88A 2P4DA 1KAVA 1LARA 2I75A 1NWEA 2AZRA 4HJPA 3QCLA 2BGDA 3QCKA 3ZM0A 4OHHA 5BZXA 5M43A 3QCJA 2NLKA 3V0HA 3F81A 1YZ4A 4ZRTA 4IKCA 3ZMQA 1P15A 4QBEA 3RZ2A 2VEUA 3D44A 1NL9A 3PS5A 4R0SA 1XBOA 3EAXA 1J4XA 4WOHA 2I5XA 2I6JA 1A5YA 3EU0A 2QCJA 3S3HA 4ERCA 4GWFA 4OHIA 1XXVA 2H03A 2VEWA 2ESBA 3ZV2A 3LJ8A 5KABA 4JMJA 4OHDA 4R30A 3CWEA 2E0TA 1RXDA 2H04A 2CNHA 2B4UA 4WU2A 1M3GA 1R6HA 3F9BA 4OHEA 5I6VA 5KA3A 4BPCA 1LYVA 2YDUA 1GWZA 2C46A 5KA7A 1OHEA 5KACA 2QCTA 3S3FA 1D5RA 4JBCA 4R0TA 2AHSA 2H02A 5J8RA 3QCIA 1YTWA 3S4EA 1BZHA 1YFOA 4QUMA 3A5KA 2GWOA 4S0GA 2Q47A 1OESA 1PTYA 1G1HA 2CNGA 2SHPA 1ZCLA 3D1QA 5KADA 4D3QA 2I6OA 2HC2A 3U96A 3EB1A 1FPRA 4OHLA 3QCMA 3QCCA 3AWEA 2I4EA 4KYQA 4GE6A 1I9TA 3GXGA 1RPMA 3O4SA 5HDEA 3BLTA 2F6YA 4GFUA 1Q6TA 4Y2EA 2F46A 2BGEA 1ZCKA 3D1OA 2BV5A 1L8KA 1C86A 2A8BA 5GTJA 3NMEA 4RI4A 3OLRA 2Y2FA 3S4OA 5K25A 2F6WA 3AWGA 4GRYA 4Y14A 4GE5A 3H2XA 5EHPA 1G7GA 1YGRA 1WCHA 2QBPA 5K9VA 2HB1A 1I9SA 4RH5A 3I7ZA 1ECVA 4D3PA 4HJQA 1PA1A 2B4OA 1YGUA 2H4KA 2NTAA 3QKQA 1NZ7A 1PTTA 1OEUA 4RDDA 5KA4A 2HNQA 4D3RA 5KA8A 1G7FA 3QCDA 3ZM2A 3BM8A 2I6MA 3S3KA 2GJTA 1QZ0A 2OUDA 2Y96A 2I6IA 5BZZA 2PBNA 2VEVA 2P6XA 4I8NA 2F6ZA 1PA9A 2CM3A 1FQ1A 2CJZA 5LXQB 1Q6JA 1JF7A 3O4UA 4PVGA 1PTVA 2G59A 1ZZWA 2HC1A 1YWFA 3F99A 2JJDA 4NYHA 1I57A 5KAAA 4QUNA 1V3AA 1YTSA 2F6TA 5KA2A 2CNEA 3ZM1A 5IBSA 3MOZA 1BZCA 2I3RA 2QBRA 3ZMPA 1OEOX 1NWLA 4NWFA 3S3EA 2J16B 2QDCA 5BUGA 2BIJA 2CNFA 1BZJA 4Z6BA 1Q6NA 1ONYA 1Q6SA 2HVLA 4PYHA 4QAPA 2M3VA 2CFVA 1JLNA 3QCHA 1C84A 1XXPA 1C87A 1XRIA 1PTUA 1EEOA 1EENA 2R0BA 2NV5A 3I80A 2GP0A 2CMAA 3D1HA 1NNYA 5K24A 2HCMA 4MBBA 3V0EA 2CNIA 4RH9A 2CMBA 2Q05A 1MKPA 3F9AA 1XM2A 4H1OA 1C85A 3QCNA 3AWFA 1U26A 1T48A 2CM7A 2J16A 1ZC0A 2QDMA 2OC3A 1WRMA 2C7SA 1X24A 2F71A 2G6ZA 5MMZB 3OMHA 2CMCA 4BJOA 2RF6A 5BX1A 4YAAA 1C83A 1YTNA 4RKKA 4JNBA 1OETA 5KA1A 3O5XA 2I4GA 4WU3A 2CM8A 2H4VA 2IMGA 3V0GA 2B4PA 3QKPA 4NWGA 3BLUA 1G1GA 2FH7A 1OHDA 2FJNA 3O4TA 4HRFA 3SMEA 3M4UA 2BZLA 4JMKA 4TVVA 2CM2A 2HXPA 1Q6PA 1FPZA 4ZN5A 2PT0A 2F70A 2QBSA 4NX8A 3RGOA 1SUGA 1PH0A 4WTYA 3O3LA 3QCBA 1ONZA 2PSZA 2MBCA 1U24A 1T49A 2OZ5A 4KI9A 1WAXA 2I1YA 2PQ5A 4NNDA 1Q6MA 3RGQA 1OEMX 1Q1MA 4DGXA 2HY3A 5K9WA 1OEVA 4RHGA 3EZZA 2F6VA 4B04A 3QCEA 3RO1A 5EHRA 4H34A 2B07A 4GE2A 3BRHA 4DGPA 4YR8B 5IBMA 2QDPA 3V0DA 4KYRA 2NT7A 3I36A 1YPTA 1OHCA 2H4GA 3B7OA 2QEPA 3D42A 4AZ1A 2F6FA 2PA5A 2ZN7A 2J17A 2VEXA 1YN9A 3F41A 2I42A 3V0FA 4QBWA 5K22A 1G4WR 3QCFA 2PI7A 3CM3A 2A3KA 3GXHA 2I4HA 1PYNA 3EMUA 5KA0A 3N0AA 3SR9A 5K23A
chains in the Genus database with same CATH superfamily
1NO6A 4GS0A 2QBQA 4CVKA 1GFYA 4QF5A 2FJMA 2DXPA 3V0JA 3ZM3A 3QCGA 4ZI4A 2JFGA 2WGPA 4ICZA 3D9CA 2NZ6A 2VEYA 2HNPA 1G1FA 1VHRA 1AAXA 1KAKA 1L8GA 2OOQA 3MMJA 4RI5A 2ZMMA 1QXKA 3A5JA 1PXHA 3MOWA 1T4JA 4GRZA 5AWXA 2B49A 4QAHA 2B3OA 2GC5A 2I3UA 2B4SA 4J51A 1G4US 3V0IA 5KA9A 2I6PA 1LQFA 1U25A 4GFVA 2NT2A 1C88A 2P4DA 2VOSA 1KAVA 1LARA 2I75A 1NWEA 2XPCA 2AZRA 4HJPA 3QCLA 2BGDA 3QCKA 3ZM0A 4OHHA 5BZXA 5M43A 2VORA 3QCJA 2NLKA 3V0HA 3F81A 2GCAA 1YZ4A 4ZRTA 4IKCA 3ZMQA 1P15A 4QBEA 3RZ2A 2VEUA 3D44A 1NL9A 1GQQA 3PS5A 4R0SA 1XBOA 3EAXA 1J4XA 1E0DA 4WOHA 2I5XA 2I6JA 4C13A 1A5YA 3EU0A 2QCJA 3S3HA 4ERCA 4GWFA 4OHIA 2Y1OA 1XXVA 2H03A 2VEWA 2ESBA 3ZV2A 3LJ8A 5KABA 4ZIYA 4JMJA 2JFHA 4OHDA 4R30A 3CWEA 4CVLA 2E0TA 1RXDA 2H04A 2CNHA 2B4UA 4WU2A 1M3GA 1R6HA 3F9BA 4OHEA 5I6VA 5KA3A 4BPCA 1LYVA 2YDUA 1GWZA 2C46A 2UAGA 5KA7A 1OHEA 5KACA 2QCTA 3S3FA 1D5RA 4JBCA 4R0TA 3QCZA 2AHSA 2H02A 5J8RA 3QCIA 1YTWA 3S4EA 1BZHA 1YFOA 4QUMA 3A5KA 2GWOA 4S0GA 3NRSA 2Q47A 1OESA 1PTYA 1G1HA 3MVNA 2CNGA 2SHPA 1ZCLA 3D1QA 5KADA 2UUOA 4D3QA 2I6OA 2HC2A 3U96A 3EB1A 1FPRA 4OHLA 3QCMA 3QCCA 1P31A 3AWEA 2I4EA 4KYQA 4GE6A 1I9TA 3GXGA 1P3DA 1RPMA 5A5FA 3O4SA 5HDEA 2UUPA 2GC6A 3BLTA 2F6YA 4GFUA 1Q6TA 4Y2EA 2F46A 2BGEA 1ZCKA 3D1OA 2BV5A 1L8KA 1C86A 2A8BA 5GTJA 3NMEA 2XJAA 4RI4A 3ZL8A 3UAGA 3OLRA 2Y2FA 3S4OA 5K25A 2F6WA 3AWGA 4GRYA 4Y14A 4GE5A 3H2XA 5EHPA 1G7GA 3LK7A 1YGRA 1W78A 1WCHA 1W7KA 2QBPA 5K9VA 2HB1A 1I9SA 4CVMA 2F00A 4RH5A 3I7ZA 1ECVA 4D3PA 4HJQA 1PA1A 2WJPA 2B4OA 1YGUA 2H4KA 2NTAA 1FGSA 3QKQA 1NZ7A 1PTTA 1OEUA 4RDDA 5KA4A 4HV4A 2HNQA 4D3RA 5KA8A 1G7FA 1J6UA 3QCDA 3ZM2A 3BM8A 2I6MA 3S3KA 2GJTA 1QZ0A 2OUDA 2Y66A 2Y96A 2JFFA 3PYZA 2I6IA 5BZZA 2PBNA 2VEVA 2P6XA 4I8NA 2F6ZA 1JBVA 1PA9A 2CM3A 1FQ1A 2CJZA 5LXQB 1Q6JA 1JF7A 3O4UA 4PVGA 1PTVA 2G59A 1ZZWA 2HC1A 1YWFA 3F99A 2JJDA 4NYHA 1I57A 5KAAA 4QUNA 1V3AA 4BUCA 1YTSA 2VTEA 2F6TA 5KA2A 2CNEA 3ZM1A 5IBSA 3MOZA 1BZCA 3ZM6A 2I3RA 2QBRA 3ZMPA 1OEOX 4C12A 1NWLA 4NWFA 3S3EA 2Y67A 2J16B 2QDCA 5BUGA 2BIJA 2CNFA 1BZJA 4Z6BA 1Q6NA 1ONYA 1Q6SA 2HVLA 4PYHA 4QAPA 2M3VA 1EEHA 2CFVA 1JLNA 3QCHA 1C84A 1XXPA 1C87A 1XRIA 1PTUA 1EEOA 1EENA 2R0BA 2NV5A 1E8CA 3I80A 2GP0A 2CMAA 3D1HA 1NNYA 5K24A 2HCMA 4MBBA 3V0EA 2CNIA 4RH9A 2CMBA 2Q05A 1MKPA 2Y68A 1UAGA 3F9AA 1XM2A 4H1OA 1C85A 3QCNA 3AWFA 1U26A 5A5EA 1T48A 4UAGA 2CM7A 2J16A 1JBWA 1ZC0A 2QDMA 2OC3A 1WRMA 2C7SA 1X24A 2F71A 2G6ZA 5MMZB 3OMHA 2CMCA 4BJOA 1GG4A 2RF6A 5BX1A 4YAAA 1C83A 1YTNA 4RKKA 4JNBA 1OETA 5KA1A 3O5XA 3ZM5A 2I4GA 3HN7A 4WU3A 2CM8A 2H4VA 2IMGA 3V0GA 2B4PA 3QKPA 2WTZA 4NWGA 3BLUA 1G1GA 2FH7A 2X5OA 1OHDA 2FJNA 3O4TA 4HRFA 3SMEA 3M4UA 2BZLA 4JMKA 4TVVA 2CM2A 2HXPA 1Q6PA 1FPZA 2VTDA 4ZN5A 2PT0A 2F70A 2QBSA 4NX8A 2GCBA 3RGOA 1SUGA 1PH0A 4WTYA 3O3LA 3QCBA 1ONZA 2PSZA 2MBCA 1U24A 1T49A 4QDIA 2AM2A 4BUBA 2OZ5A 4KI9A 1WAXA 2I1YA 2PQ5A 4NNDA 1Q6MA 3RGQA 1OEMX 1Q1MA 4DGXA 1O5ZA 2HY3A 5K9WA 1OEVA 4RHGA 3EZZA 2F6VA 4B04A 3QCEA 3RO1A 5EHRA 4H34A 2B07A 4GE2A 1GQYA 3BRHA 4DGPA 4YR8B 5IBMA 2QDPA 3V0DA 4KYRA 2NT7A 3I36A 1YPTA 1OHCA 2H4GA 3B7OA 2AM1A 2QEPA 3D42A 4AZ1A 2F6FA 2PA5A 2ZN7A 2J17A 2VEXA 1YN9A 3F41A 2I42A 3V0FA 4QBWA 5K22A 1G4WR 3QCFA 2PI7A 3CM3A 2A3KA 3GXHA 2I4HA 1PYNA 3EMUA 5KA0A 3N2AA 3N0AA 3SR9A 5K23A
chains in the Genus database with same CATH topology
1NO6A 4GS0A 2QBQA 1GFYA 2FJMA 2DXPA 3V0JA 3ZM3A 3QCGA 4ZI4A 2WGPA 4ICZA 3D9CA 2NZ6A 2VEYA 2HNPA 1G1FA 1VHRA 1AAXA 1KAKA 1L8GA 2OOQA 3MMJA 4RI5A 2ZMMA 1QXKA 3A5JA 1PXHA 3MOWA 1T4JA 4GRZA 5AWXA 2B49A 4QAHA 2B3OA 2I3UA 2B4SA 4J51A 1G4US 3V0IA 5KA9A 2I6PA 1LQFA 1U25A 4GFVA 2NT2A 1C88A 2P4DA 1KAVA 1LARA 2I75A 1NWEA 2AZRA 4HJPA 3QCLA 2BGDA 3QCKA 3ZM0A 4OHHA 5BZXA 5M43A 3QCJA 2NLKA 3V0HA 3F81A 1YZ4A 4ZRTA 4IKCA 3ZMQA 1P15A 4QBEA 3RZ2A 2VEUA 3D44A 1NL9A 3PS5A 4R0SA 1XBOA 3EAXA 1J4XA 4WOHA 2I5XA 2I6JA 1A5YA 3EU0A 2QCJA 3S3HA 4ERCA 4GWFA 4OHIA 1XXVA 2H03A 2VEWA 2ESBA 3ZV2A 3LJ8A 5KABA 4JMJA 4OHDA 4R30A 3CWEA 2E0TA 1RXDA 2H04A 2CNHA 2B4UA 4WU2A 1M3GA 1R6HA 3F9BA 4OHEA 5I6VA 5KA3A 4BPCA 1LYVA 2YDUA 1GWZA 2C46A 5KA7A 1OHEA 5KACA 2QCTA 3S3FA 1D5RA 4JBCA 4R0TA 2AHSA 2H02A 5J8RA 3QCIA 1YTWA 3S4EA 1BZHA 1YFOA 4QUMA 3A5KA 2GWOA 4S0GA 2Q47A 1OESA 1PTYA 1G1HA 2CNGA 2SHPA 1ZCLA 3D1QA 5KADA 4D3QA 2I6OA 2HC2A 3U96A 3EB1A 1FPRA 4OHLA 3QCMA 3QCCA 3AWEA 2I4EA 4KYQA 4GE6A 1I9TA 3GXGA 1RPMA 3O4SA 5HDEA 3BLTA 2F6YA 4GFUA 1Q6TA 4Y2EA 2F46A 2BGEA 1ZCKA 3D1OA 2BV5A 1L8KA 1C86A 2A8BA 5GTJA 3NMEA 4RI4A 3OLRA 2Y2FA 3S4OA 5K25A 2F6WA 3AWGA 4GRYA 4Y14A 4GE5A 3H2XA 5EHPA 1G7GA 1YGRA 1WCHA 2QBPA 5K9VA 2HB1A 1I9SA 4RH5A 3I7ZA 1ECVA 4D3PA 4HJQA 1PA1A 2B4OA 1YGUA 2H4KA 2NTAA 3QKQA 1NZ7A 1PTTA 1OEUA 4RDDA 5KA4A 2HNQA 4D3RA 5KA8A 1G7FA 3QCDA 3ZM2A 3BM8A 2I6MA 3S3KA 2GJTA 1QZ0A 2OUDA 2Y96A 2I6IA 5BZZA 2PBNA 2VEVA 2P6XA 4I8NA 2F6ZA 1PA9A 2CM3A 1FQ1A 2CJZA 5LXQB 1Q6JA 1JF7A 3O4UA 4PVGA 1PTVA 2G59A 1ZZWA 2HC1A 1YWFA 3F99A 2JJDA 4NYHA 1I57A 5KAAA 4QUNA 1V3AA 1YTSA 2F6TA 5KA2A 2CNEA 3ZM1A 5IBSA 3MOZA 1BZCA 2I3RA 2QBRA 3ZMPA 1OEOX 1NWLA 4NWFA 3S3EA 2J16B 2QDCA 5BUGA 2BIJA 2CNFA 1BZJA 4Z6BA 1Q6NA 1ONYA 1Q6SA 2HVLA 4PYHA 4QAPA 2M3VA 2CFVA 1JLNA 3QCHA 1C84A 1XXPA 1C87A 1XRIA 1PTUA 1EEOA 1EENA 2R0BA 2NV5A 3I80A 2GP0A 2CMAA 3D1HA 1NNYA 5K24A 2HCMA 4MBBA 3V0EA 2CNIA 4RH9A 2CMBA 2Q05A 1MKPA 3F9AA 1XM2A 4H1OA 1C85A 3QCNA 3AWFA 1U26A 1T48A 2CM7A 2J16A 1ZC0A 2QDMA 2OC3A 1WRMA 2C7SA 1X24A 2F71A 2G6ZA 5MMZB 3OMHA 2CMCA 4BJOA 2RF6A 5BX1A 4YAAA 1C83A 1YTNA 4RKKA 4JNBA 1OETA 5KA1A 3O5XA 2I4GA 4WU3A 2CM8A 2H4VA 2IMGA 3V0GA 2B4PA 3QKPA 4NWGA 3BLUA 1G1GA 2FH7A 1OHDA 2FJNA 3O4TA 4HRFA 3SMEA 3M4UA 2BZLA 4JMKA 4TVVA 2CM2A 2HXPA 1Q6PA 1FPZA 4ZN5A 2PT0A 2F70A 2QBSA 4NX8A 3RGOA 1SUGA 1PH0A 4WTYA 3O3LA 3QCBA 1ONZA 2PSZA 2MBCA 1U24A 1T49A 2OZ5A 4KI9A 1WAXA 2I1YA 2PQ5A 4NNDA 1Q6MA 3RGQA 1OEMX 1Q1MA 4DGXA 2HY3A 5K9WA 1OEVA 4RHGA 3EZZA 2F6VA 4B04A 3QCEA 3RO1A 5EHRA 4H34A 2B07A 4GE2A 3BRHA 4DGPA 4YR8B 5IBMA 2QDPA 3V0DA 4KYRA 2NT7A 3I36A 1YPTA 1OHCA 2H4GA 3B7OA 2QEPA 3D42A 4AZ1A 2F6FA 2PA5A 2ZN7A 2J17A 2VEXA 1YN9A 3F41A 2I42A 3V0FA 4QBWA 5K22A 1G4WR 3QCFA 2PI7A 3CM3A 2A3KA 3GXHA 2I4HA 1PYNA 3EMUA 5KA0A 3N0AA 3SR9A 5K23A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NO6 A;  4GS0 A;  2QBQ A;  1GFY A;  2FJM A;  2DXP A;  3V0J A;  3ZM3 A;  3QCG A;  4ZI4 A;  2WGP A;  4ICZ A;  3D9C A;  2NZ6 A;  2VEY A;  2HNP A;  1G1F A;  1VHR A;  1AAX A;  1KAK A;  1L8G A;  2OOQ A;  3MMJ A;  4RI5 A;  2ZMM A;  1QXK A;  3A5J A;  1PXH A;  3MOW A;  1T4J A;  4GRZ A;  5AWX A;  2B49 A;  4QAH A;  2B3O A;  2I3U A;  2B4S A;  4J51 A;  1G4U S;  3V0I A;  5KA9 A;  2I6P A;  1LQF A;  1U25 A;  4GFV A;  2NT2 A;  1C88 A;  2P4D A;  1KAV A;  1LAR A;  2I75 A;  1NWE A;  2AZR A;  4HJP A;  3QCL A;  2BGD A;  3QCK A;  3ZM0 A;  4OHH A;  5BZX A;  5M43 A;  3QCJ A;  2NLK A;  3V0H A;  3F81 A;  1YZ4 A;  4ZRT A;  4IKC A;  3ZMQ A;  1P15 A;  4QBE A;  3RZ2 A;  2VEU A;  3D44 A;  1NL9 A;  3PS5 A;  4R0S A;  1XBO A;  3EAX A;  1J4X A;  4WOH A;  2I5X A;  2I6J A;  1A5Y A;  3EU0 A;  2QCJ A;  3S3H A;  4ERC A;  4GWF A;  4OHI A;  1XXV A;  2H03 A;  2VEW A;  2ESB A;  3ZV2 A;  3LJ8 A;  5KAB A;  4JMJ A;  4OHD A;  4R30 A;  3CWE A;  2E0T A;  1RXD A;  2H04 A;  2CNH A;  2B4U A;  4WU2 A;  1M3G A;  1R6H A;  3F9B A;  4OHE A;  5I6V A;  5KA3 A;  4BPC A;  1LYV A;  2YDU A;  1GWZ A;  2C46 A;  5KA7 A;  1OHE A;  5KAC A;  2QCT A;  3S3F A;  1D5R A;  4JBC A;  4R0T A;  2AHS A;  2H02 A;  5J8R A;  3QCI A;  1YTW A;  3S4E A;  1BZH A;  1YFO A;  4QUM A;  3A5K A;  2GWO A;  4S0G A;  2Q47 A;  1OES A;  1PTY A;  1G1H A;  2CNG A;  2SHP A;  1ZCL A;  3D1Q A;  5KAD A;  4D3Q A;  2I6O A;  2HC2 A;  3U96 A;  3EB1 A;  1FPR A;  4OHL A;  3QCM A;  3QCC A;  3AWE A;  2I4E A;  4KYQ A;  4GE6 A;  1I9T A;  3GXG A;  1RPM A;  3O4S A;  5HDE A;  3BLT A;  2F6Y A;  4GFU A;  1Q6T A;  4Y2E A;  2F46 A;  2BGE A;  1ZCK A;  3D1O A;  2BV5 A;  1L8K A;  1C86 A;  2A8B A;  5GTJ A;  3NME A;  4RI4 A;  3OLR A;  2Y2F A;  3S4O A;  5K25 A;  2F6W A;  3AWG A;  4GRY A;  4Y14 A;  4GE5 A;  3H2X A;  5EHP A;  1G7G A;  1YGR A;  1WCH A;  2QBP A;  5K9V A;  2HB1 A;  1I9S A;  4RH5 A;  3I7Z A;  1ECV A;  4D3P A;  4HJQ A;  1PA1 A;  2B4O A;  1YGU A;  2H4K A;  2NTA A;  3QKQ A;  1NZ7 A;  1PTT A;  1OEU A;  4RDD A;  5KA4 A;  2HNQ A;  4D3R A;  5KA8 A;  1G7F A;  3QCD A;  3ZM2 A;  3BM8 A;  2I6M A;  3S3K A;  2GJT A;  1QZ0 A;  2OUD A;  2Y96 A;  2I6I A;  5BZZ A;  2PBN A;  2VEV A;  2P6X A;  4I8N A;  2F6Z A;  1PA9 A;  2CM3 A;  1FQ1 A;  2CJZ A;  5LXQ B;  1Q6J A;  1JF7 A;  3O4U A;  4PVG A;  1PTV A;  2G59 A;  1ZZW A;  2HC1 A;  1YWF A;  3F99 A;  2JJD A;  4NYH A;  1I57 A;  5KAA A;  4QUN A;  1V3A A;  1YTS A;  2F6T A;  5KA2 A;  2CNE A;  3ZM1 A;  5IBS A;  3MOZ A;  1BZC A;  2I3R A;  2QBR A;  3ZMP A;  1OEO X;  1NWL A;  4NWF A;  3S3E A;  2J16 B;  2QDC A;  5BUG A;  2BIJ A;  2CNF A;  1BZJ A;  4Z6B A;  1Q6N A;  1ONY A;  1Q6S A;  2HVL A;  4PYH A;  4QAP A;  2M3V A;  2CFV A;  1JLN A;  3QCH A;  1C84 A;  1XXP A;  1C87 A;  1XRI A;  1PTU A;  1EEO A;  1EEN A;  2R0B A;  2NV5 A;  3I80 A;  2GP0 A;  2CMA A;  3D1H A;  1NNY A;  5K24 A;  2HCM A;  4MBB A;  3V0E A;  2CNI A;  4RH9 A;  2CMB A;  2Q05 A;  1MKP A;  3F9A A;  1XM2 A;  4H1O A;  1C85 A;  3QCN A;  3AWF A;  1U26 A;  1T48 A;  2CM7 A;  2J16 A;  1ZC0 A;  2QDM A;  2OC3 A;  1WRM A;  2C7S A;  1X24 A;  2F71 A;  2G6Z A;  5MMZ B;  3OMH A;  2CMC A;  4BJO A;  2RF6 A;  5BX1 A;  4YAA A;  1C83 A;  1YTN A;  4RKK A;  4JNB A;  1OET A;  5KA1 A;  3O5X A;  2I4G A;  4WU3 A;  2CM8 A;  2H4V A;  2IMG A;  3V0G A;  2B4P A;  3QKP A;  4NWG A;  3BLU A;  1G1G A;  2FH7 A;  1OHD A;  2FJN A;  3O4T A;  4HRF A;  3SME A;  3M4U A;  2BZL A;  4JMK A;  4TVV A;  2CM2 A;  2HXP A;  1Q6P A;  1FPZ A;  4ZN5 A;  2PT0 A;  2F70 A;  2QBS A;  4NX8 A;  3RGO A;  1SUG A;  1PH0 A;  4WTY A;  3O3L A;  3QCB A;  1ONZ A;  2PSZ A;  2MBC A;  1U24 A;  1T49 A;  2OZ5 A;  4KI9 A;  1WAX A;  2I1Y A;  2PQ5 A;  4NND A;  1Q6M A;  3RGQ A;  1OEM X;  1Q1M A;  4DGX A;  2HY3 A;  5K9W A;  1OEV A;  4RHG A;  3EZZ A;  2F6V A;  4B04 A;  3QCE A;  3RO1 A;  5EHR A;  4H34 A;  2B07 A;  4GE2 A;  3BRH A;  4DGP A;  4YR8 B;  5IBM A;  2QDP A;  3V0D A;  4KYR A;  2NT7 A;  3I36 A;  1YPT A;  1OHC A;  2H4G A;  3B7O A;  2QEP A;  3D42 A;  4AZ1 A;  2F6F A;  2PA5 A;  2ZN7 A;  2J17 A;  2VEX A;  1YN9 A;  3F41 A;  2I42 A;  3V0F A;  4QBW A;  5K22 A;  1G4W R;  3QCF A;  2PI7 A;  3CM3 A;  2A3K A;  3GXH A;  2I4H A;  1PYN A;  3EMU A;  5KA0 A;  3N0A A;  3SR9 A;  5K23 A; 
#chains in the Genus database with same CATH topology
 1NO6 A;  4GS0 A;  2QBQ A;  4CVK A;  1GFY A;  4QF5 A;  2FJM A;  2DXP A;  3V0J A;  3ZM3 A;  3QCG A;  4ZI4 A;  2JFG A;  2WGP A;  4ICZ A;  3D9C A;  2NZ6 A;  2VEY A;  2HNP A;  1G1F A;  1VHR A;  1AAX A;  1KAK A;  1L8G A;  2OOQ A;  3MMJ A;  4RI5 A;  2ZMM A;  1QXK A;  3A5J A;  1PXH A;  3MOW A;  1T4J A;  4GRZ A;  5AWX A;  2B49 A;  4QAH A;  2B3O A;  2GC5 A;  2I3U A;  2B4S A;  4J51 A;  1G4U S;  3V0I A;  5KA9 A;  2I6P A;  1LQF A;  1U25 A;  4GFV A;  2NT2 A;  1C88 A;  2P4D A;  2VOS A;  1KAV A;  1LAR A;  2I75 A;  1NWE A;  2XPC A;  2AZR A;  4HJP A;  3QCL A;  2BGD A;  3QCK A;  3ZM0 A;  4OHH A;  5BZX A;  5M43 A;  2VOR A;  3QCJ A;  2NLK A;  3V0H A;  3F81 A;  2GCA A;  1YZ4 A;  4ZRT A;  4IKC A;  3ZMQ A;  1P15 A;  4QBE A;  3RZ2 A;  2VEU A;  3D44 A;  1NL9 A;  1GQQ A;  3PS5 A;  4R0S A;  1XBO A;  3EAX A;  1J4X A;  1E0D A;  4WOH A;  2I5X A;  2I6J A;  4C13 A;  1A5Y A;  3EU0 A;  2QCJ A;  3S3H A;  4ERC A;  4GWF A;  4OHI A;  2Y1O A;  1XXV A;  2H03 A;  2VEW A;  2ESB A;  3ZV2 A;  3LJ8 A;  5KAB A;  4ZIY A;  4JMJ A;  2JFH A;  4OHD A;  4R30 A;  3CWE A;  4CVL A;  2E0T A;  1RXD A;  2H04 A;  2CNH A;  2B4U A;  4WU2 A;  1M3G A;  1R6H A;  3F9B A;  4OHE A;  5I6V A;  5KA3 A;  4BPC A;  1LYV A;  2YDU A;  1GWZ A;  2C46 A;  2UAG A;  5KA7 A;  1OHE A;  5KAC A;  2QCT A;  3S3F A;  1D5R A;  4JBC A;  4R0T A;  3QCZ A;  2AHS A;  2H02 A;  5J8R A;  3QCI A;  1YTW A;  3S4E A;  1BZH A;  1YFO A;  4QUM A;  3A5K A;  2GWO A;  4S0G A;  3NRS A;  2Q47 A;  1OES A;  1PTY A;  1G1H A;  3MVN A;  2CNG A;  2SHP A;  1ZCL A;  3D1Q A;  5KAD A;  2UUO A;  4D3Q A;  2I6O A;  2HC2 A;  3U96 A;  3EB1 A;  1FPR A;  4OHL A;  3QCM A;  3QCC A;  1P31 A;  3AWE A;  2I4E A;  4KYQ A;  4GE6 A;  1I9T A;  3GXG A;  1P3D A;  1RPM A;  5A5F A;  3O4S A;  5HDE A;  2UUP A;  2GC6 A;  3BLT A;  2F6Y A;  4GFU A;  1Q6T A;  4Y2E A;  2F46 A;  2BGE A;  1ZCK A;  3D1O A;  2BV5 A;  1L8K A;  1C86 A;  2A8B A;  5GTJ A;  3NME A;  2XJA A;  4RI4 A;  3ZL8 A;  3UAG A;  3OLR A;  2Y2F A;  3S4O A;  5K25 A;  2F6W A;  3AWG A;  4GRY A;  4Y14 A;  4GE5 A;  3H2X A;  5EHP A;  1G7G A;  3LK7 A;  1YGR A;  1W78 A;  1WCH A;  1W7K A;  2QBP A;  5K9V A;  2HB1 A;  1I9S A;  4CVM A;  2F00 A;  4RH5 A;  3I7Z A;  1ECV A;  4D3P A;  4HJQ A;  1PA1 A;  2WJP A;  2B4O A;  1YGU A;  2H4K A;  2NTA A;  1FGS A;  3QKQ A;  1NZ7 A;  1PTT A;  1OEU A;  4RDD A;  5KA4 A;  4HV4 A;  2HNQ A;  4D3R A;  5KA8 A;  1G7F A;  1J6U A;  3QCD A;  3ZM2 A;  3BM8 A;  2I6M A;  3S3K A;  2GJT A;  1QZ0 A;  2OUD A;  2Y66 A;  2Y96 A;  2JFF A;  3PYZ A;  2I6I A;  5BZZ A;  2PBN A;  2VEV A;  2P6X A;  4I8N A;  2F6Z A;  1JBV A;  1PA9 A;  2CM3 A;  1FQ1 A;  2CJZ A;  5LXQ B;  1Q6J A;  1JF7 A;  3O4U A;  4PVG A;  1PTV A;  2G59 A;  1ZZW A;  2HC1 A;  1YWF A;  3F99 A;  2JJD A;  4NYH A;  1I57 A;  5KAA A;  4QUN A;  1V3A A;  4BUC A;  1YTS A;  2VTE A;  2F6T A;  5KA2 A;  2CNE A;  3ZM1 A;  5IBS A;  3MOZ A;  1BZC A;  3ZM6 A;  2I3R A;  2QBR A;  3ZMP A;  1OEO X;  4C12 A;  1NWL A;  4NWF A;  3S3E A;  2Y67 A;  2J16 B;  2QDC A;  5BUG A;  2BIJ A;  2CNF A;  1BZJ A;  4Z6B A;  1Q6N A;  1ONY A;  1Q6S A;  2HVL A;  4PYH A;  4QAP A;  2M3V A;  1EEH A;  2CFV A;  1JLN A;  3QCH A;  1C84 A;  1XXP A;  1C87 A;  1XRI A;  1PTU A;  1EEO A;  1EEN A;  2R0B A;  2NV5 A;  1E8C A;  3I80 A;  2GP0 A;  2CMA A;  3D1H A;  1NNY A;  5K24 A;  2HCM A;  4MBB A;  3V0E A;  2CNI A;  4RH9 A;  2CMB A;  2Q05 A;  1MKP A;  2Y68 A;  1UAG A;  3F9A A;  1XM2 A;  4H1O A;  1C85 A;  3QCN A;  3AWF A;  1U26 A;  5A5E A;  1T48 A;  4UAG A;  2CM7 A;  2J16 A;  1JBW A;  1ZC0 A;  2QDM A;  2OC3 A;  1WRM A;  2C7S A;  1X24 A;  2F71 A;  2G6Z A;  5MMZ B;  3OMH A;  2CMC A;  4BJO A;  1GG4 A;  2RF6 A;  5BX1 A;  4YAA A;  1C83 A;  1YTN A;  4RKK A;  4JNB A;  1OET A;  5KA1 A;  3O5X A;  3ZM5 A;  2I4G A;  3HN7 A;  4WU3 A;  2CM8 A;  2H4V A;  2IMG A;  3V0G A;  2B4P A;  3QKP A;  2WTZ A;  4NWG A;  3BLU A;  1G1G A;  2FH7 A;  2X5O A;  1OHD A;  2FJN A;  3O4T A;  4HRF A;  3SME A;  3M4U A;  2BZL A;  4JMK A;  4TVV A;  2CM2 A;  2HXP A;  1Q6P A;  1FPZ A;  2VTD A;  4ZN5 A;  2PT0 A;  2F70 A;  2QBS A;  4NX8 A;  2GCB A;  3RGO A;  1SUG A;  1PH0 A;  4WTY A;  3O3L A;  3QCB A;  1ONZ A;  2PSZ A;  2MBC A;  1U24 A;  1T49 A;  4QDI A;  2AM2 A;  4BUB A;  2OZ5 A;  4KI9 A;  1WAX A;  2I1Y A;  2PQ5 A;  4NND A;  1Q6M A;  3RGQ A;  1OEM X;  1Q1M A;  4DGX A;  1O5Z A;  2HY3 A;  5K9W A;  1OEV A;  4RHG A;  3EZZ A;  2F6V A;  4B04 A;  3QCE A;  3RO1 A;  5EHR A;  4H34 A;  2B07 A;  4GE2 A;  1GQY A;  3BRH A;  4DGP A;  4YR8 B;  5IBM A;  2QDP A;  3V0D A;  4KYR A;  2NT7 A;  3I36 A;  1YPT A;  1OHC A;  2H4G A;  3B7O A;  2AM1 A;  2QEP A;  3D42 A;  4AZ1 A;  2F6F A;  2PA5 A;  2ZN7 A;  2J17 A;  2VEX A;  1YN9 A;  3F41 A;  2I42 A;  3V0F A;  4QBW A;  5K22 A;  1G4W R;  3QCF A;  2PI7 A;  3CM3 A;  2A3K A;  3GXH A;  2I4H A;  1PYN A;  3EMU A;  5KA0 A;  3N2A A;  3N0A A;  3SR9 A;  5K23 A; 
#chains in the Genus database with same CATH homology
 1NO6 A;  4GS0 A;  2QBQ A;  1GFY A;  2FJM A;  2DXP A;  3V0J A;  3ZM3 A;  3QCG A;  4ZI4 A;  2WGP A;  4ICZ A;  3D9C A;  2NZ6 A;  2VEY A;  2HNP A;  1G1F A;  1VHR A;  1AAX A;  1KAK A;  1L8G A;  2OOQ A;  3MMJ A;  4RI5 A;  2ZMM A;  1QXK A;  3A5J A;  1PXH A;  3MOW A;  1T4J A;  4GRZ A;  5AWX A;  2B49 A;  4QAH A;  2B3O A;  2I3U A;  2B4S A;  4J51 A;  1G4U S;  3V0I A;  5KA9 A;  2I6P A;  1LQF A;  1U25 A;  4GFV A;  2NT2 A;  1C88 A;  2P4D A;  1KAV A;  1LAR A;  2I75 A;  1NWE A;  2AZR A;  4HJP A;  3QCL A;  2BGD A;  3QCK A;  3ZM0 A;  4OHH A;  5BZX A;  5M43 A;  3QCJ A;  2NLK A;  3V0H A;  3F81 A;  1YZ4 A;  4ZRT A;  4IKC A;  3ZMQ A;  1P15 A;  4QBE A;  3RZ2 A;  2VEU A;  3D44 A;  1NL9 A;  3PS5 A;  4R0S A;  1XBO A;  3EAX A;  1J4X A;  4WOH A;  2I5X A;  2I6J A;  1A5Y A;  3EU0 A;  2QCJ A;  3S3H A;  4ERC A;  4GWF A;  4OHI A;  1XXV A;  2H03 A;  2VEW A;  2ESB A;  3ZV2 A;  3LJ8 A;  5KAB A;  4JMJ A;  4OHD A;  4R30 A;  3CWE A;  2E0T A;  1RXD A;  2H04 A;  2CNH A;  2B4U A;  4WU2 A;  1M3G A;  1R6H A;  3F9B A;  4OHE A;  5I6V A;  5KA3 A;  4BPC A;  1LYV A;  2YDU A;  1GWZ A;  2C46 A;  5KA7 A;  1OHE A;  5KAC A;  2QCT A;  3S3F A;  1D5R A;  4JBC A;  4R0T A;  2AHS A;  2H02 A;  5J8R A;  3QCI A;  1YTW A;  3S4E A;  1BZH A;  1YFO A;  4QUM A;  3A5K A;  2GWO A;  4S0G A;  2Q47 A;  1OES A;  1PTY A;  1G1H A;  2CNG A;  2SHP A;  1ZCL A;  3D1Q A;  5KAD A;  4D3Q A;  2I6O A;  2HC2 A;  3U96 A;  3EB1 A;  1FPR A;  4OHL A;  3QCM A;  3QCC A;  3AWE A;  2I4E A;  4KYQ A;  4GE6 A;  1I9T A;  3GXG A;  1RPM A;  3O4S A;  5HDE A;  3BLT A;  2F6Y A;  4GFU A;  1Q6T A;  4Y2E A;  2F46 A;  2BGE A;  1ZCK A;  3D1O A;  2BV5 A;  1L8K A;  1C86 A;  2A8B A;  5GTJ A;  3NME A;  4RI4 A;  3OLR A;  2Y2F A;  3S4O A;  5K25 A;  2F6W A;  3AWG A;  4GRY A;  4Y14 A;  4GE5 A;  3H2X A;  5EHP A;  1G7G A;  1YGR A;  1WCH A;  2QBP A;  5K9V A;  2HB1 A;  1I9S A;  4RH5 A;  3I7Z A;  1ECV A;  4D3P A;  4HJQ A;  1PA1 A;  2B4O A;  1YGU A;  2H4K A;  2NTA A;  3QKQ A;  1NZ7 A;  1PTT A;  1OEU A;  4RDD A;  5KA4 A;  2HNQ A;  4D3R A;  5KA8 A;  1G7F A;  3QCD A;  3ZM2 A;  3BM8 A;  2I6M A;  3S3K A;  2GJT A;  1QZ0 A;  2OUD A;  2Y96 A;  2I6I A;  5BZZ A;  2PBN A;  2VEV A;  2P6X A;  4I8N A;  2F6Z A;  1PA9 A;  2CM3 A;  1FQ1 A;  2CJZ A;  5LXQ B;  1Q6J A;  1JF7 A;  3O4U A;  4PVG A;  1PTV A;  2G59 A;  1ZZW A;  2HC1 A;  1YWF A;  3F99 A;  2JJD A;  4NYH A;  1I57 A;  5KAA A;  4QUN A;  1V3A A;  1YTS A;  2F6T A;  5KA2 A;  2CNE A;  3ZM1 A;  5IBS A;  3MOZ A;  1BZC A;  2I3R A;  2QBR A;  3ZMP A;  1OEO X;  1NWL A;  4NWF A;  3S3E A;  2J16 B;  2QDC A;  5BUG A;  2BIJ A;  2CNF A;  1BZJ A;  4Z6B A;  1Q6N A;  1ONY A;  1Q6S A;  2HVL A;  4PYH A;  4QAP A;  2M3V A;  2CFV A;  1JLN A;  3QCH A;  1C84 A;  1XXP A;  1C87 A;  1XRI A;  1PTU A;  1EEO A;  1EEN A;  2R0B A;  2NV5 A;  3I80 A;  2GP0 A;  2CMA A;  3D1H A;  1NNY A;  5K24 A;  2HCM A;  4MBB A;  3V0E A;  2CNI A;  4RH9 A;  2CMB A;  2Q05 A;  1MKP A;  3F9A A;  1XM2 A;  4H1O A;  1C85 A;  3QCN A;  3AWF A;  1U26 A;  1T48 A;  2CM7 A;  2J16 A;  1ZC0 A;  2QDM A;  2OC3 A;  1WRM A;  2C7S A;  1X24 A;  2F71 A;  2G6Z A;  5MMZ B;  3OMH A;  2CMC A;  4BJO A;  2RF6 A;  5BX1 A;  4YAA A;  1C83 A;  1YTN A;  4RKK A;  4JNB A;  1OET A;  5KA1 A;  3O5X A;  2I4G A;  4WU3 A;  2CM8 A;  2H4V A;  2IMG A;  3V0G A;  2B4P A;  3QKP A;  4NWG A;  3BLU A;  1G1G A;  2FH7 A;  1OHD A;  2FJN A;  3O4T A;  4HRF A;  3SME A;  3M4U A;  2BZL A;  4JMK A;  4TVV A;  2CM2 A;  2HXP A;  1Q6P A;  1FPZ A;  4ZN5 A;  2PT0 A;  2F70 A;  2QBS A;  4NX8 A;  3RGO A;  1SUG A;  1PH0 A;  4WTY A;  3O3L A;  3QCB A;  1ONZ A;  2PSZ A;  2MBC A;  1U24 A;  1T49 A;  2OZ5 A;  4KI9 A;  1WAX A;  2I1Y A;  2PQ5 A;  4NND A;  1Q6M A;  3RGQ A;  1OEM X;  1Q1M A;  4DGX A;  2HY3 A;  5K9W A;  1OEV A;  4RHG A;  3EZZ A;  2F6V A;  4B04 A;  3QCE A;  3RO1 A;  5EHR A;  4H34 A;  2B07 A;  4GE2 A;  3BRH A;  4DGP A;  4YR8 B;  5IBM A;  2QDP A;  3V0D A;  4KYR A;  2NT7 A;  3I36 A;  1YPT A;  1OHC A;  2H4G A;  3B7O A;  2QEP A;  3D42 A;  4AZ1 A;  2F6F A;  2PA5 A;  2ZN7 A;  2J17 A;  2VEX A;  1YN9 A;  3F41 A;  2I42 A;  3V0F A;  4QBW A;  5K22 A;  1G4W R;  3QCF A;  2PI7 A;  3CM3 A;  2A3K A;  3GXH A;  2I4H A;  1PYN A;  3EMU A;  5KA0 A;  3N0A A;  3SR9 A;  5K23 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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