4QAHA

The second sphere residue t263 is important for function and activity of ptp1b through modulating wpd loop
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
299
structure length
299
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQKADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 104
structure length 299
sequence length 299
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2014-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4qahA00
2M3VA 3F99A 2HNPA 4H34A 2B07A 4KI9A 1YTNA 1OEMX 1ONZA 4RH9A 4NWFA 2VEWA 5K25A 5MMZB 3QCFA 5KADA 3QCIA 4QAPA 2BGDA 1U24A 5BX1A 2PBNA 5KA4A 1WAXA 5BZZA 1U26A 2HXPA 2I42A 1NZ7A 3QCMA 5KABA 2I4GA 5LXQB 1X24A 1Q6PA 5BUGA 2HY3A 2CNGA 2GWOA 5IBSA 1KAVA 5HDEA 3O4SA 3BLUA 1G7FA 3SMEA 2MBCA 1Q1MA 2AZRA 1YWFA 4Y14A 1G1FA 1NWEA 3BM8A 1GWZA 3BRHA 4WOHA 4KYQA 1OETA 3CWEA 3H2XA 3ZM2A 2NT7A 4RHGA 3QCLA 1MKPA 3U96A 5KA1A 2OUDA 3ZMPA 1VHRA 4GE6A 5J8RA 3A5JA 3F41A 3O4UA 2F6FA 2BZLA 2B3OA 2CNHA 2QDMA 3GXHA 5KA9A 3D9CA 4AZ1A 3AWFA 3D1QA 4QUMA 4JBCA 4DGXA 4H1OA 2H4VA 2VEVA 2PA5A 1ZZWA 5KA3A 1Q6MA 4OHIA 1PTUA 5KA2A 2J16A 1G4WR 4GRZA 1V3AA 2P6XA 1JF7A 2I6MA 3QKPA 1QXKA 2HB1A 1Q6JA 1PXHA 3GXGA 5K24A 1Q6NA 1NNYA 2CMAA 3ZM1A 1PH0A 5GTJA 1OHDA 4HRFA 2PQ5A 1QZ0A 1AAXA 2HC2A 1C87A 1EEOA 1ZCLA 2Q47A 4Y2EA 4YAAA 1J4XA 4RDDA 4GRYA 2F70A 2G6ZA 2CM8A 2CNIA 4OHLA 4NWGA 1OEOX 4D3PA 1OEVA 2A8BA 3O4TA 3QKQA 2E0TA 4JNBA 5K22A 5KA8A 4KYRA 4OHDA 3B7OA 1ECVA 2YDUA 3QCCA 2DXPA 1T4JA 2NV5A 3S3EA 1T49A 2AHSA 1I9SA 2F6WA 3F81A 3V0HA 5KA7A 1NL9A 2HC1A 2NLKA 3QCDA 4YR8B 4OHEA 1U25A 2NZ6A 2QBQA 2I75A 1P15A 1PA1A 4WTYA 4Z6BA 2B4PA 1A5YA 3S4EA 2JJDA 3V0DA 4GE5A 4QBEA 4D3QA 1Q6TA 2Y2FA 1YN9A 3EAXA 3LJ8A 3EMUA 4QUNA 1KAKA 1NWLA 1D5RA 1ZC0A 4WU3A 3SR9A 4PVGA 2I6JA 1LYVA 2OOQA 2I3RA 2B4SA 3S3FA 2P4DA 3O3LA 3V0JA 1I57A 2QCJA 2PT0A 2H02A 2J16B 4NYHA 1OESA 1YZ4A 3N0AA 2QDPA 2HNQA 3PS5A 1OEUA 1JLNA 2F71A 5K9WA 1G1GA 3EU0A 5EHPA 2F6ZA 1SUGA 1R6HA 3MMJA 2ZMMA 2FJNA 1L8GA 2I3UA 5KA0A 1G7GA 5KACA 2J17A 1BZJA 2I1YA 1WRMA 5EHRA 3ZV2A 2CMCA 4HJPA 3OLRA 1YGRA 3V0FA 5IBMA 1L8KA 2GP0A 4QAHA 3V0GA 1PYNA 2R0BA 1PTYA 5K9VA 4GE2A 2I5XA 1XXVA 1YGUA 1C84A 5AWXA 1PA9A 4BJOA 4ICZA 4QBWA 4GWFA 3D42A 3A5KA 1YPTA 1FQ1A 4ZI4A 4TVVA 2C46A 3AWEA 2C7SA 3I80A 5BZXA 2FH7A 1ONYA 2PI7A 3I36A 2VEXA 3EB1A 2B4UA 5M43A 4R30A 2CM3A 2I6OA 2QBSA 3QCNA 1WCHA 4J51A 2CNFA 2SHPA 2H03A 3V0EA 3ZM3A 1YFOA 4ZN5A 2H04A 3F9BA 3QCGA 4D3RA 4MBBA 1LQFA 5KAAA 2F46A 3S4OA 1YTSA 4JMJA 1OHCA 2B49A 1YTWA 3CM3A 1C85A 2VEUA 2NT2A 1XM2A 4DGPA 3MOWA 1XRIA 2NTAA 2BV5A 3QCHA 5K23A 3S3KA 3D44A 1RPMA 2HCMA 4I8NA 2IMGA 3RZ2A 2Y96A 1C88A 2OZ5A 3RGOA 3V0IA 2CMBA 3QCJA 1C86A 2G59A 1XBOA 2QDCA 4RKKA 4ZRTA 3S3HA 2QEPA 4S0GA 2CFVA 2Q05A 1BZCA 4B04A 4R0TA 3RO1A 1PTVA 2CNEA 3D1HA 3ZMQA 2WGPA 3NMEA 1G4US 3EZZA 2RF6A 2ESBA 3BLTA 4RI5A 2GJTA 1T48A 3MOZA 4NNDA 2A3KA 2QCTA 1BZHA 1G1HA 4WU2A 1Q6SA 2BGEA 3QCEA 4GS0A 2F6VA 2I4EA 2F6YA 2VEYA 3AWGA 3O5XA 3RGQA 1RXDA 4R0SA 2I4HA 4NX8A 4OHHA 2BIJA 3OMHA 3ZM0A 4GFVA 1LARA 2HVLA 1ZCKA 2F6TA 4RH5A 1FPRA 1M3GA 3M4UA 2H4GA 2H4KA 2I6PA 1C83A 4BPCA 2B4OA 3I7ZA 2CM2A 4GFUA 4JMKA 2QBRA 2FJMA 2QBPA 3QCKA 3D1OA 3F9AA 1NO6A 4HJQA 2CM7A 1OHEA 1GFYA 1XXPA 4RI4A 4ERCA 1EENA 2CJZA 4IKCA 2PSZA 1I9TA 2ZN7A 2OC3A 5I6VA 2I6IA 4PYHA 1PTTA 3QCBA 1FPZA
chains in the Genus database with same CATH superfamily
2M3VA 3F99A 2HNPA 4H34A 2B07A 4KI9A 1YTNA 1OEMX 1ONZA 4RH9A 4NWFA 2VEWA 5K25A 5MMZB 3QCFA 2AM1A 2F00A 5KADA 3QCIA 4QAPA 2BGDA 1U24A 5BX1A 2PBNA 5KA4A 1WAXA 5BZZA 1U26A 2HXPA 2I42A 4C13A 1NZ7A 3QCMA 5KABA 2I4GA 5LXQB 1X24A 1Q6PA 5BUGA 2HY3A 2CNGA 3LK7A 2GWOA 5IBSA 1E0DA 1KAVA 5HDEA 3ZM5A 3O4SA 3BLUA 1G7FA 3SMEA 1O5ZA 2MBCA 1Q1MA 2AZRA 1YWFA 4Y14A 1G1FA 2X5OA 1NWEA 3BM8A 1GWZA 3BRHA 4WOHA 4KYQA 1OETA 4ZIYA 3CWEA 2VORA 3H2XA 3ZM2A 2NT7A 4RHGA 3QCLA 1MKPA 3U96A 5KA1A 2OUDA 3ZMPA 1VHRA 4GE6A 5J8RA 3A5JA 3F41A 3O4UA 2F6FA 2BZLA 2WTZA 2B3OA 2CNHA 2QDMA 3GXHA 5KA9A 2JFHA 3D9CA 4AZ1A 2Y66A 3AWFA 3D1QA 4QUMA 4JBCA 4DGXA 4H1OA 2H4VA 2VEVA 2PA5A 1ZZWA 5KA3A 1Q6MA 4OHIA 1PTUA 5KA2A 4HV4A 2J16A 1G4WR 4GRZA 1E8CA 1V3AA 2P6XA 3UAGA 1JF7A 2I6MA 3QKPA 1QXKA 2HB1A 1JBWA 1Q6JA 1PXHA 3GXGA 5K24A 1Q6NA 1NNYA 2CMAA 3ZM1A 1PH0A 5GTJA 1OHDA 4HRFA 2PQ5A 1QZ0A 1AAXA 2HC2A 1C87A 1EEOA 1ZCLA 2Q47A 4Y2EA 4YAAA 1J4XA 4RDDA 2UUPA 4GRYA 2F70A 2G6ZA 1GG4A 2CM8A 2CNIA 4OHLA 4NWGA 1OEOX 4D3PA 1OEVA 2A8BA 3O4TA 3QKQA 2E0TA 4JNBA 5K22A 5KA8A 4KYRA 4OHDA 3B7OA 1ECVA 2YDUA 3QCCA 2DXPA 1T4JA 2NV5A 3S3EA 1W78A 1T49A 2AHSA 1I9SA 2F6WA 3F81A 3V0HA 5KA7A 2JFGA 1NL9A 2UAGA 2HC1A 2NLKA 3QCDA 3QCBA 4YR8B 4OHEA 1U25A 2NZ6A 2QBQA 2I75A 5A5EA 1P15A 1PA1A 4WTYA 4Z6BA 2B4PA 2VOSA 1A5YA 3S4EA 2JJDA 3V0DA 4GE5A 4QBEA 4D3QA 1Q6TA 3NRSA 3N2AA 2Y2FA 1YN9A 3EAXA 3LJ8A 3EMUA 4QUNA 1KAKA 2GC6A 1NWLA 1D5RA 2Y67A 1J6UA 1ZC0A 4WU3A 3SR9A 4PVGA 2I6JA 2VTDA 1LYVA 2OOQA 2Y68A 2I3RA 2B4SA 3S3FA 2P4DA 3O3LA 3V0JA 1I57A 2QCJA 2XPCA 2PT0A 2H02A 2J16B 4NYHA 1OESA 1YZ4A 3N0AA 2QDPA 2HNQA 3PS5A 4CVMA 1OEUA 1JLNA 2F71A 5K9WA 1G1GA 3EU0A 5EHPA 2F6ZA 1SUGA 1R6HA 3ZL8A 3MMJA 2ZMMA 5A5FA 2FJNA 4BUCA 1L8GA 2I3UA 5KA0A 3QCZA 1G7GA 5KACA 2J17A 1BZJA 2I1YA 1WRMA 5EHRA 3ZV2A 2CMCA 4HJPA 3OLRA 1YGRA 3V0FA 5IBMA 1L8KA 2GP0A 4QAHA 2GCAA 3V0GA 1PYNA 2R0BA 1PTYA 5K9VA 4GE2A 2I5XA 1XXVA 1YGUA 1C84A 5AWXA 2JFFA 1PA9A 4BJOA 4ICZA 4QBWA 4GWFA 3D42A 3A5KA 1YPTA 1FQ1A 4ZI4A 4TVVA 2C46A 3AWEA 2C7SA 3I80A 2WJPA 5BZXA 2FH7A 1ONYA 2PI7A 3I36A 2VEXA 3EB1A 2B4UA 5M43A 4R30A 2CM3A 2I6OA 2QBSA 3QCNA 1WCHA 4J51A 2CNFA 2SHPA 2H03A 3V0EA 3ZM3A 1YFOA 4ZN5A 2H04A 3F9BA 3QCGA 4D3RA 4MBBA 1LQFA 5KAAA 2F46A 3S4OA 4BUBA 1YTSA 4JMJA 1OHCA 2B49A 1YTWA 3CM3A 3HN7A 1C85A 2GCBA 2VEUA 2NT2A 1XM2A 4DGPA 3MOWA 4CVKA 3ZM6A 1XRIA 2NTAA 2BV5A 3QCHA 5K23A 3S3KA 3D44A 1RPMA 2HCMA 4I8NA 2IMGA 3RZ2A 2Y96A 1EEHA 1C88A 2OZ5A 3RGOA 3V0IA 2CMBA 4QF5A 3QCJA 1C86A 2G59A 1XBOA 2QDCA 4RKKA 4ZRTA 3S3HA 2QEPA 2GC5A 4S0GA 2CFVA 2Q05A 1BZCA 4B04A 4R0TA 3RO1A 1PTVA 2CNEA 3D1HA 3ZMQA 1P3DA 2WGPA 1W7KA 3NMEA 1G4US 1GQYA 3EZZA 2RF6A 2ESBA 3BLTA 4CVLA 1GQQA 2VTEA 4RI5A 2GJTA 1T48A 3MOZA 4NNDA 2A3KA 2QCTA 1BZHA 1G1HA 4WU2A 1Q6SA 2BGEA 3QCEA 4GS0A 2F6VA 2I4EA 2F6YA 2VEYA 3AWGA 3O5XA 3RGQA 1RXDA 4R0SA 2I4HA 4NX8A 4OHHA 2BIJA 3OMHA 1UAGA 3ZM0A 4GFVA 1LARA 2HVLA 1ZCKA 2F6TA 4RH5A 1FPRA 1JBVA 1M3GA 2UUOA 2H4GA 3M4UA 2H4KA 2I6PA 3PYZA 1C83A 2Y1OA 4BPCA 2B4OA 3I7ZA 2CM2A 4GFUA 4JMKA 2QBRA 2FJMA 2QBPA 3QCKA 3D1OA 3F9AA 1NO6A 4HJQA 2CM7A 1OHEA 1GFYA 1XXPA 1P31A 4QDIA 4RI4A 4UAGA 4ERCA 1EENA 2CJZA 4IKCA 2PSZA 1I9TA 2ZN7A 4C12A 3MVNA 2OC3A 5I6VA 2XJAA 2I6IA 1FGSA 4PYHA 1PTTA 2AM2A 1FPZA
chains in the Genus database with same CATH topology
2M3VA 3F99A 2HNPA 4H34A 2B07A 4KI9A 1YTNA 1OEMX 1ONZA 4RH9A 4NWFA 2VEWA 5K25A 5MMZB 3QCFA 5KADA 3QCIA 4QAPA 2BGDA 1U24A 5BX1A 2PBNA 5KA4A 1WAXA 5BZZA 1U26A 2HXPA 2I42A 1NZ7A 3QCMA 5KABA 2I4GA 5LXQB 1X24A 1Q6PA 5BUGA 2HY3A 2CNGA 2GWOA 5IBSA 1KAVA 5HDEA 3O4SA 3BLUA 1G7FA 3SMEA 2MBCA 1Q1MA 2AZRA 1YWFA 4Y14A 1G1FA 1NWEA 3BM8A 1GWZA 3BRHA 4WOHA 4KYQA 1OETA 3CWEA 3H2XA 3ZM2A 2NT7A 4RHGA 3QCLA 1MKPA 3U96A 5KA1A 2OUDA 3ZMPA 1VHRA 4GE6A 5J8RA 3A5JA 3F41A 3O4UA 2F6FA 2BZLA 2B3OA 2CNHA 2QDMA 3GXHA 5KA9A 3D9CA 4AZ1A 3AWFA 3D1QA 4QUMA 4JBCA 4DGXA 4H1OA 2H4VA 2VEVA 2PA5A 1ZZWA 5KA3A 1Q6MA 4OHIA 1PTUA 5KA2A 2J16A 1G4WR 4GRZA 1V3AA 2P6XA 1JF7A 2I6MA 3QKPA 1QXKA 2HB1A 1Q6JA 1PXHA 3GXGA 5K24A 1Q6NA 1NNYA 2CMAA 3ZM1A 1PH0A 5GTJA 1OHDA 4HRFA 2PQ5A 1QZ0A 1AAXA 2HC2A 1C87A 1EEOA 1ZCLA 2Q47A 4Y2EA 4YAAA 1J4XA 4RDDA 4GRYA 2F70A 2G6ZA 2CM8A 2CNIA 4OHLA 4NWGA 1OEOX 4D3PA 1OEVA 2A8BA 3O4TA 3QKQA 2E0TA 4JNBA 5K22A 5KA8A 4KYRA 4OHDA 3B7OA 1ECVA 2YDUA 3QCCA 2DXPA 1T4JA 2NV5A 3S3EA 1T49A 2AHSA 1I9SA 2F6WA 3F81A 3V0HA 5KA7A 1NL9A 2HC1A 2NLKA 3QCDA 4YR8B 4OHEA 1U25A 2NZ6A 2QBQA 2I75A 1P15A 1PA1A 4WTYA 4Z6BA 2B4PA 1A5YA 3S4EA 2JJDA 3V0DA 4GE5A 4QBEA 4D3QA 1Q6TA 2Y2FA 1YN9A 3EAXA 3LJ8A 3EMUA 4QUNA 1KAKA 1NWLA 1D5RA 1ZC0A 4WU3A 3SR9A 4PVGA 2I6JA 1LYVA 2OOQA 2I3RA 2B4SA 3S3FA 2P4DA 3O3LA 3V0JA 1I57A 2QCJA 2PT0A 2H02A 2J16B 4NYHA 1OESA 1YZ4A 3N0AA 2QDPA 2HNQA 3PS5A 1OEUA 1JLNA 2F71A 5K9WA 1G1GA 3EU0A 5EHPA 2F6ZA 1SUGA 1R6HA 3MMJA 2ZMMA 2FJNA 1L8GA 2I3UA 5KA0A 1G7GA 5KACA 2J17A 1BZJA 2I1YA 1WRMA 5EHRA 3ZV2A 2CMCA 4HJPA 3OLRA 1YGRA 3V0FA 5IBMA 1L8KA 2GP0A 4QAHA 3V0GA 1PYNA 2R0BA 1PTYA 5K9VA 4GE2A 2I5XA 1XXVA 1YGUA 1C84A 5AWXA 1PA9A 4BJOA 4ICZA 4QBWA 4GWFA 3D42A 3A5KA 1YPTA 1FQ1A 4ZI4A 4TVVA 2C46A 3AWEA 2C7SA 3I80A 5BZXA 2FH7A 1ONYA 2PI7A 3I36A 2VEXA 3EB1A 2B4UA 5M43A 4R30A 2CM3A 2I6OA 2QBSA 3QCNA 1WCHA 4J51A 2CNFA 2SHPA 2H03A 3V0EA 3ZM3A 1YFOA 4ZN5A 2H04A 3F9BA 3QCGA 4D3RA 4MBBA 1LQFA 5KAAA 2F46A 3S4OA 1YTSA 4JMJA 1OHCA 2B49A 1YTWA 3CM3A 1C85A 2VEUA 2NT2A 1XM2A 4DGPA 3MOWA 1XRIA 2NTAA 2BV5A 3QCHA 5K23A 3S3KA 3D44A 1RPMA 2HCMA 4I8NA 2IMGA 3RZ2A 2Y96A 1C88A 2OZ5A 3RGOA 3V0IA 2CMBA 3QCJA 1C86A 2G59A 1XBOA 2QDCA 4RKKA 4ZRTA 3S3HA 2QEPA 4S0GA 2CFVA 2Q05A 1BZCA 4B04A 4R0TA 3RO1A 1PTVA 2CNEA 3D1HA 3ZMQA 2WGPA 3NMEA 1G4US 3EZZA 2RF6A 2ESBA 3BLTA 4RI5A 2GJTA 1T48A 3MOZA 4NNDA 2A3KA 2QCTA 1BZHA 1G1HA 4WU2A 1Q6SA 2BGEA 3QCEA 4GS0A 2F6VA 2I4EA 2F6YA 2VEYA 3AWGA 3O5XA 3RGQA 1RXDA 4R0SA 2I4HA 4NX8A 4OHHA 2BIJA 3OMHA 3ZM0A 4GFVA 1LARA 2HVLA 1ZCKA 2F6TA 4RH5A 1FPRA 1M3GA 3M4UA 2H4GA 2H4KA 2I6PA 1C83A 4BPCA 2B4OA 3I7ZA 2CM2A 4GFUA 4JMKA 2QBRA 2FJMA 2QBPA 3QCKA 3D1OA 3F9AA 1NO6A 4HJQA 2CM7A 1OHEA 1GFYA 1XXPA 4RI4A 4ERCA 1EENA 2CJZA 4IKCA 2PSZA 1I9TA 2ZN7A 2OC3A 5I6VA 2I6IA 4PYHA 1PTTA 3QCBA 1FPZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2M3V A;  3F99 A;  2HNP A;  4H34 A;  2B07 A;  4KI9 A;  1YTN A;  1OEM X;  1ONZ A;  4RH9 A;  4NWF A;  2VEW A;  5K25 A;  5MMZ B;  3QCF A;  5KAD A;  3QCI A;  4QAP A;  2BGD A;  1U24 A;  5BX1 A;  2PBN A;  5KA4 A;  1WAX A;  5BZZ A;  1U26 A;  2HXP A;  2I42 A;  1NZ7 A;  3QCM A;  5KAB A;  2I4G A;  5LXQ B;  1X24 A;  1Q6P A;  5BUG A;  2HY3 A;  2CNG A;  2GWO A;  5IBS A;  1KAV A;  5HDE A;  3O4S A;  3BLU A;  1G7F A;  3SME A;  2MBC A;  1Q1M A;  2AZR A;  1YWF A;  4Y14 A;  1G1F A;  1NWE A;  3BM8 A;  1GWZ A;  3BRH A;  4WOH A;  4KYQ A;  1OET A;  3CWE A;  3H2X A;  3ZM2 A;  2NT7 A;  4RHG A;  3QCL A;  1MKP A;  3U96 A;  5KA1 A;  2OUD A;  3ZMP A;  1VHR A;  4GE6 A;  5J8R A;  3A5J A;  3F41 A;  3O4U A;  2F6F A;  2BZL A;  2B3O A;  2CNH A;  2QDM A;  3GXH A;  5KA9 A;  3D9C A;  4AZ1 A;  3AWF A;  3D1Q A;  4QUM A;  4JBC A;  4DGX A;  4H1O A;  2H4V A;  2VEV A;  2PA5 A;  1ZZW A;  5KA3 A;  1Q6M A;  4OHI A;  1PTU A;  5KA2 A;  2J16 A;  1G4W R;  4GRZ A;  1V3A A;  2P6X A;  1JF7 A;  2I6M A;  3QKP A;  1QXK A;  2HB1 A;  1Q6J A;  1PXH A;  3GXG A;  5K24 A;  1Q6N A;  1NNY A;  2CMA A;  3ZM1 A;  1PH0 A;  5GTJ A;  1OHD A;  4HRF A;  2PQ5 A;  1QZ0 A;  1AAX A;  2HC2 A;  1C87 A;  1EEO A;  1ZCL A;  2Q47 A;  4Y2E A;  4YAA A;  1J4X A;  4RDD A;  4GRY A;  2F70 A;  2G6Z A;  2CM8 A;  2CNI A;  4OHL A;  4NWG A;  1OEO X;  4D3P A;  1OEV A;  2A8B A;  3O4T A;  3QKQ A;  2E0T A;  4JNB A;  5K22 A;  5KA8 A;  4KYR A;  4OHD A;  3B7O A;  1ECV A;  2YDU A;  3QCC A;  2DXP A;  1T4J A;  2NV5 A;  3S3E A;  1T49 A;  2AHS A;  1I9S A;  2F6W A;  3F81 A;  3V0H A;  5KA7 A;  1NL9 A;  2HC1 A;  2NLK A;  3QCD A;  4YR8 B;  4OHE A;  1U25 A;  2NZ6 A;  2QBQ A;  2I75 A;  1P15 A;  1PA1 A;  4WTY A;  4Z6B A;  2B4P A;  1A5Y A;  3S4E A;  2JJD A;  3V0D A;  4GE5 A;  4QBE A;  4D3Q A;  1Q6T A;  2Y2F A;  1YN9 A;  3EAX A;  3LJ8 A;  3EMU A;  4QUN A;  1KAK A;  1NWL A;  1D5R A;  1ZC0 A;  4WU3 A;  3SR9 A;  4PVG A;  2I6J A;  1LYV A;  2OOQ A;  2I3R A;  2B4S A;  3S3F A;  2P4D A;  3O3L A;  3V0J A;  1I57 A;  2QCJ A;  2PT0 A;  2H02 A;  2J16 B;  4NYH A;  1OES A;  1YZ4 A;  3N0A A;  2QDP A;  2HNQ A;  3PS5 A;  1OEU A;  1JLN A;  2F71 A;  5K9W A;  1G1G A;  3EU0 A;  5EHP A;  2F6Z A;  1SUG A;  1R6H A;  3MMJ A;  2ZMM A;  2FJN A;  1L8G A;  2I3U A;  5KA0 A;  1G7G A;  5KAC A;  2J17 A;  1BZJ A;  2I1Y A;  1WRM A;  5EHR A;  3ZV2 A;  2CMC A;  4HJP A;  3OLR A;  1YGR A;  3V0F A;  5IBM A;  1L8K A;  2GP0 A;  4QAH A;  3V0G A;  1PYN A;  2R0B A;  1PTY A;  5K9V A;  4GE2 A;  2I5X A;  1XXV A;  1YGU A;  1C84 A;  5AWX A;  1PA9 A;  4BJO A;  4ICZ A;  4QBW A;  4GWF A;  3D42 A;  3A5K A;  1YPT A;  1FQ1 A;  4ZI4 A;  4TVV A;  2C46 A;  3AWE A;  2C7S A;  3I80 A;  5BZX A;  2FH7 A;  1ONY A;  2PI7 A;  3I36 A;  2VEX A;  3EB1 A;  2B4U A;  5M43 A;  4R30 A;  2CM3 A;  2I6O A;  2QBS A;  3QCN A;  1WCH A;  4J51 A;  2CNF A;  2SHP A;  2H03 A;  3V0E A;  3ZM3 A;  1YFO A;  4ZN5 A;  2H04 A;  3F9B A;  3QCG A;  4D3R A;  4MBB A;  1LQF A;  5KAA A;  2F46 A;  3S4O A;  1YTS A;  4JMJ A;  1OHC A;  2B49 A;  1YTW A;  3CM3 A;  1C85 A;  2VEU A;  2NT2 A;  1XM2 A;  4DGP A;  3MOW A;  1XRI A;  2NTA A;  2BV5 A;  3QCH A;  5K23 A;  3S3K A;  3D44 A;  1RPM A;  2HCM A;  4I8N A;  2IMG A;  3RZ2 A;  2Y96 A;  1C88 A;  2OZ5 A;  3RGO A;  3V0I A;  2CMB A;  3QCJ A;  1C86 A;  2G59 A;  1XBO A;  2QDC A;  4RKK A;  4ZRT A;  3S3H A;  2QEP A;  4S0G A;  2CFV A;  2Q05 A;  1BZC A;  4B04 A;  4R0T A;  3RO1 A;  1PTV A;  2CNE A;  3D1H A;  3ZMQ A;  2WGP A;  3NME A;  1G4U S;  3EZZ A;  2RF6 A;  2ESB A;  3BLT A;  4RI5 A;  2GJT A;  1T48 A;  3MOZ A;  4NND A;  2A3K A;  2QCT A;  1BZH A;  1G1H A;  4WU2 A;  1Q6S A;  2BGE A;  3QCE A;  4GS0 A;  2F6V A;  2I4E A;  2F6Y A;  2VEY A;  3AWG A;  3O5X A;  3RGQ A;  1RXD A;  4R0S A;  2I4H A;  4NX8 A;  4OHH A;  2BIJ A;  3OMH A;  3ZM0 A;  4GFV A;  1LAR A;  2HVL A;  1ZCK A;  2F6T A;  4RH5 A;  1FPR A;  1M3G A;  3M4U A;  2H4G A;  2H4K A;  2I6P A;  1C83 A;  4BPC A;  2B4O A;  3I7Z A;  2CM2 A;  4GFU A;  4JMK A;  2QBR A;  2FJM A;  2QBP A;  3QCK A;  3D1O A;  3F9A A;  1NO6 A;  4HJQ A;  2CM7 A;  1OHE A;  1GFY A;  1XXP A;  4RI4 A;  4ERC A;  1EEN A;  2CJZ A;  4IKC A;  2PSZ A;  1I9T A;  2ZN7 A;  2OC3 A;  5I6V A;  2I6I A;  4PYH A;  1PTT A;  3QCB A;  1FPZ A; 
#chains in the Genus database with same CATH topology
 2M3V A;  3F99 A;  2HNP A;  4H34 A;  2B07 A;  4KI9 A;  1YTN A;  1OEM X;  1ONZ A;  4RH9 A;  4NWF A;  2VEW A;  5K25 A;  5MMZ B;  3QCF A;  2AM1 A;  2F00 A;  5KAD A;  3QCI A;  4QAP A;  2BGD A;  1U24 A;  5BX1 A;  2PBN A;  5KA4 A;  1WAX A;  5BZZ A;  1U26 A;  2HXP A;  2I42 A;  4C13 A;  1NZ7 A;  3QCM A;  5KAB A;  2I4G A;  5LXQ B;  1X24 A;  1Q6P A;  5BUG A;  2HY3 A;  2CNG A;  3LK7 A;  2GWO A;  5IBS A;  1E0D A;  1KAV A;  5HDE A;  3ZM5 A;  3O4S A;  3BLU A;  1G7F A;  3SME A;  1O5Z A;  2MBC A;  1Q1M A;  2AZR A;  1YWF A;  4Y14 A;  1G1F A;  2X5O A;  1NWE A;  3BM8 A;  1GWZ A;  3BRH A;  4WOH A;  4KYQ A;  1OET A;  4ZIY A;  3CWE A;  2VOR A;  3H2X A;  3ZM2 A;  2NT7 A;  4RHG A;  3QCL A;  1MKP A;  3U96 A;  5KA1 A;  2OUD A;  3ZMP A;  1VHR A;  4GE6 A;  5J8R A;  3A5J A;  3F41 A;  3O4U A;  2F6F A;  2BZL A;  2WTZ A;  2B3O A;  2CNH A;  2QDM A;  3GXH A;  5KA9 A;  2JFH A;  3D9C A;  4AZ1 A;  2Y66 A;  3AWF A;  3D1Q A;  4QUM A;  4JBC A;  4DGX A;  4H1O A;  2H4V A;  2VEV A;  2PA5 A;  1ZZW A;  5KA3 A;  1Q6M A;  4OHI A;  1PTU A;  5KA2 A;  4HV4 A;  2J16 A;  1G4W R;  4GRZ A;  1E8C A;  1V3A A;  2P6X A;  3UAG A;  1JF7 A;  2I6M A;  3QKP A;  1QXK A;  2HB1 A;  1JBW A;  1Q6J A;  1PXH A;  3GXG A;  5K24 A;  1Q6N A;  1NNY A;  2CMA A;  3ZM1 A;  1PH0 A;  5GTJ A;  1OHD A;  4HRF A;  2PQ5 A;  1QZ0 A;  1AAX A;  2HC2 A;  1C87 A;  1EEO A;  1ZCL A;  2Q47 A;  4Y2E A;  4YAA A;  1J4X A;  4RDD A;  2UUP A;  4GRY A;  2F70 A;  2G6Z A;  1GG4 A;  2CM8 A;  2CNI A;  4OHL A;  4NWG A;  1OEO X;  4D3P A;  1OEV A;  2A8B A;  3O4T A;  3QKQ A;  2E0T A;  4JNB A;  5K22 A;  5KA8 A;  4KYR A;  4OHD A;  3B7O A;  1ECV A;  2YDU A;  3QCC A;  2DXP A;  1T4J A;  2NV5 A;  3S3E A;  1W78 A;  1T49 A;  2AHS A;  1I9S A;  2F6W A;  3F81 A;  3V0H A;  5KA7 A;  2JFG A;  1NL9 A;  2UAG A;  2HC1 A;  2NLK A;  3QCD A;  3QCB A;  4YR8 B;  4OHE A;  1U25 A;  2NZ6 A;  2QBQ A;  2I75 A;  5A5E A;  1P15 A;  1PA1 A;  4WTY A;  4Z6B A;  2B4P A;  2VOS A;  1A5Y A;  3S4E A;  2JJD A;  3V0D A;  4GE5 A;  4QBE A;  4D3Q A;  1Q6T A;  3NRS A;  3N2A A;  2Y2F A;  1YN9 A;  3EAX A;  3LJ8 A;  3EMU A;  4QUN A;  1KAK A;  2GC6 A;  1NWL A;  1D5R A;  2Y67 A;  1J6U A;  1ZC0 A;  4WU3 A;  3SR9 A;  4PVG A;  2I6J A;  2VTD A;  1LYV A;  2OOQ A;  2Y68 A;  2I3R A;  2B4S A;  3S3F A;  2P4D A;  3O3L A;  3V0J A;  1I57 A;  2QCJ A;  2XPC A;  2PT0 A;  2H02 A;  2J16 B;  4NYH A;  1OES A;  1YZ4 A;  3N0A A;  2QDP A;  2HNQ A;  3PS5 A;  4CVM A;  1OEU A;  1JLN A;  2F71 A;  5K9W A;  1G1G A;  3EU0 A;  5EHP A;  2F6Z A;  1SUG A;  1R6H A;  3ZL8 A;  3MMJ A;  2ZMM A;  5A5F A;  2FJN A;  4BUC A;  1L8G A;  2I3U A;  5KA0 A;  3QCZ A;  1G7G A;  5KAC A;  2J17 A;  1BZJ A;  2I1Y A;  1WRM A;  5EHR A;  3ZV2 A;  2CMC A;  4HJP A;  3OLR A;  1YGR A;  3V0F A;  5IBM A;  1L8K A;  2GP0 A;  4QAH A;  2GCA A;  3V0G A;  1PYN A;  2R0B A;  1PTY A;  5K9V A;  4GE2 A;  2I5X A;  1XXV A;  1YGU A;  1C84 A;  5AWX A;  2JFF A;  1PA9 A;  4BJO A;  4ICZ A;  4QBW A;  4GWF A;  3D42 A;  3A5K A;  1YPT A;  1FQ1 A;  4ZI4 A;  4TVV A;  2C46 A;  3AWE A;  2C7S A;  3I80 A;  2WJP A;  5BZX A;  2FH7 A;  1ONY A;  2PI7 A;  3I36 A;  2VEX A;  3EB1 A;  2B4U A;  5M43 A;  4R30 A;  2CM3 A;  2I6O A;  2QBS A;  3QCN A;  1WCH A;  4J51 A;  2CNF A;  2SHP A;  2H03 A;  3V0E A;  3ZM3 A;  1YFO A;  4ZN5 A;  2H04 A;  3F9B A;  3QCG A;  4D3R A;  4MBB A;  1LQF A;  5KAA A;  2F46 A;  3S4O A;  4BUB A;  1YTS A;  4JMJ A;  1OHC A;  2B49 A;  1YTW A;  3CM3 A;  3HN7 A;  1C85 A;  2GCB A;  2VEU A;  2NT2 A;  1XM2 A;  4DGP A;  3MOW A;  4CVK A;  3ZM6 A;  1XRI A;  2NTA A;  2BV5 A;  3QCH A;  5K23 A;  3S3K A;  3D44 A;  1RPM A;  2HCM A;  4I8N A;  2IMG A;  3RZ2 A;  2Y96 A;  1EEH A;  1C88 A;  2OZ5 A;  3RGO A;  3V0I A;  2CMB A;  4QF5 A;  3QCJ A;  1C86 A;  2G59 A;  1XBO A;  2QDC A;  4RKK A;  4ZRT A;  3S3H A;  2QEP A;  2GC5 A;  4S0G A;  2CFV A;  2Q05 A;  1BZC A;  4B04 A;  4R0T A;  3RO1 A;  1PTV A;  2CNE A;  3D1H A;  3ZMQ A;  1P3D A;  2WGP A;  1W7K A;  3NME A;  1G4U S;  1GQY A;  3EZZ A;  2RF6 A;  2ESB A;  3BLT A;  4CVL A;  1GQQ A;  2VTE A;  4RI5 A;  2GJT A;  1T48 A;  3MOZ A;  4NND A;  2A3K A;  2QCT A;  1BZH A;  1G1H A;  4WU2 A;  1Q6S A;  2BGE A;  3QCE A;  4GS0 A;  2F6V A;  2I4E A;  2F6Y A;  2VEY A;  3AWG A;  3O5X A;  3RGQ A;  1RXD A;  4R0S A;  2I4H A;  4NX8 A;  4OHH A;  2BIJ A;  3OMH A;  1UAG A;  3ZM0 A;  4GFV A;  1LAR A;  2HVL A;  1ZCK A;  2F6T A;  4RH5 A;  1FPR A;  1JBV A;  1M3G A;  2UUO A;  2H4G A;  3M4U A;  2H4K A;  2I6P A;  3PYZ A;  1C83 A;  2Y1O A;  4BPC A;  2B4O A;  3I7Z A;  2CM2 A;  4GFU A;  4JMK A;  2QBR A;  2FJM A;  2QBP A;  3QCK A;  3D1O A;  3F9A A;  1NO6 A;  4HJQ A;  2CM7 A;  1OHE A;  1GFY A;  1XXP A;  1P31 A;  4QDI A;  4RI4 A;  4UAG A;  4ERC A;  1EEN A;  2CJZ A;  4IKC A;  2PSZ A;  1I9T A;  2ZN7 A;  4C12 A;  3MVN A;  2OC3 A;  5I6V A;  2XJA A;  2I6I A;  1FGS A;  4PYH A;  1PTT A;  2AM2 A;  1FPZ A; 
#chains in the Genus database with same CATH homology
 2M3V A;  3F99 A;  2HNP A;  4H34 A;  2B07 A;  4KI9 A;  1YTN A;  1OEM X;  1ONZ A;  4RH9 A;  4NWF A;  2VEW A;  5K25 A;  5MMZ B;  3QCF A;  5KAD A;  3QCI A;  4QAP A;  2BGD A;  1U24 A;  5BX1 A;  2PBN A;  5KA4 A;  1WAX A;  5BZZ A;  1U26 A;  2HXP A;  2I42 A;  1NZ7 A;  3QCM A;  5KAB A;  2I4G A;  5LXQ B;  1X24 A;  1Q6P A;  5BUG A;  2HY3 A;  2CNG A;  2GWO A;  5IBS A;  1KAV A;  5HDE A;  3O4S A;  3BLU A;  1G7F A;  3SME A;  2MBC A;  1Q1M A;  2AZR A;  1YWF A;  4Y14 A;  1G1F A;  1NWE A;  3BM8 A;  1GWZ A;  3BRH A;  4WOH A;  4KYQ A;  1OET A;  3CWE A;  3H2X A;  3ZM2 A;  2NT7 A;  4RHG A;  3QCL A;  1MKP A;  3U96 A;  5KA1 A;  2OUD A;  3ZMP A;  1VHR A;  4GE6 A;  5J8R A;  3A5J A;  3F41 A;  3O4U A;  2F6F A;  2BZL A;  2B3O A;  2CNH A;  2QDM A;  3GXH A;  5KA9 A;  3D9C A;  4AZ1 A;  3AWF A;  3D1Q A;  4QUM A;  4JBC A;  4DGX A;  4H1O A;  2H4V A;  2VEV A;  2PA5 A;  1ZZW A;  5KA3 A;  1Q6M A;  4OHI A;  1PTU A;  5KA2 A;  2J16 A;  1G4W R;  4GRZ A;  1V3A A;  2P6X A;  1JF7 A;  2I6M A;  3QKP A;  1QXK A;  2HB1 A;  1Q6J A;  1PXH A;  3GXG A;  5K24 A;  1Q6N A;  1NNY A;  2CMA A;  3ZM1 A;  1PH0 A;  5GTJ A;  1OHD A;  4HRF A;  2PQ5 A;  1QZ0 A;  1AAX A;  2HC2 A;  1C87 A;  1EEO A;  1ZCL A;  2Q47 A;  4Y2E A;  4YAA A;  1J4X A;  4RDD A;  4GRY A;  2F70 A;  2G6Z A;  2CM8 A;  2CNI A;  4OHL A;  4NWG A;  1OEO X;  4D3P A;  1OEV A;  2A8B A;  3O4T A;  3QKQ A;  2E0T A;  4JNB A;  5K22 A;  5KA8 A;  4KYR A;  4OHD A;  3B7O A;  1ECV A;  2YDU A;  3QCC A;  2DXP A;  1T4J A;  2NV5 A;  3S3E A;  1T49 A;  2AHS A;  1I9S A;  2F6W A;  3F81 A;  3V0H A;  5KA7 A;  1NL9 A;  2HC1 A;  2NLK A;  3QCD A;  4YR8 B;  4OHE A;  1U25 A;  2NZ6 A;  2QBQ A;  2I75 A;  1P15 A;  1PA1 A;  4WTY A;  4Z6B A;  2B4P A;  1A5Y A;  3S4E A;  2JJD A;  3V0D A;  4GE5 A;  4QBE A;  4D3Q A;  1Q6T A;  2Y2F A;  1YN9 A;  3EAX A;  3LJ8 A;  3EMU A;  4QUN A;  1KAK A;  1NWL A;  1D5R A;  1ZC0 A;  4WU3 A;  3SR9 A;  4PVG A;  2I6J A;  1LYV A;  2OOQ A;  2I3R A;  2B4S A;  3S3F A;  2P4D A;  3O3L A;  3V0J A;  1I57 A;  2QCJ A;  2PT0 A;  2H02 A;  2J16 B;  4NYH A;  1OES A;  1YZ4 A;  3N0A A;  2QDP A;  2HNQ A;  3PS5 A;  1OEU A;  1JLN A;  2F71 A;  5K9W A;  1G1G A;  3EU0 A;  5EHP A;  2F6Z A;  1SUG A;  1R6H A;  3MMJ A;  2ZMM A;  2FJN A;  1L8G A;  2I3U A;  5KA0 A;  1G7G A;  5KAC A;  2J17 A;  1BZJ A;  2I1Y A;  1WRM A;  5EHR A;  3ZV2 A;  2CMC A;  4HJP A;  3OLR A;  1YGR A;  3V0F A;  5IBM A;  1L8K A;  2GP0 A;  4QAH A;  3V0G A;  1PYN A;  2R0B A;  1PTY A;  5K9V A;  4GE2 A;  2I5X A;  1XXV A;  1YGU A;  1C84 A;  5AWX A;  1PA9 A;  4BJO A;  4ICZ A;  4QBW A;  4GWF A;  3D42 A;  3A5K A;  1YPT A;  1FQ1 A;  4ZI4 A;  4TVV A;  2C46 A;  3AWE A;  2C7S A;  3I80 A;  5BZX A;  2FH7 A;  1ONY A;  2PI7 A;  3I36 A;  2VEX A;  3EB1 A;  2B4U A;  5M43 A;  4R30 A;  2CM3 A;  2I6O A;  2QBS A;  3QCN A;  1WCH A;  4J51 A;  2CNF A;  2SHP A;  2H03 A;  3V0E A;  3ZM3 A;  1YFO A;  4ZN5 A;  2H04 A;  3F9B A;  3QCG A;  4D3R A;  4MBB A;  1LQF A;  5KAA A;  2F46 A;  3S4O A;  1YTS A;  4JMJ A;  1OHC A;  2B49 A;  1YTW A;  3CM3 A;  1C85 A;  2VEU A;  2NT2 A;  1XM2 A;  4DGP A;  3MOW A;  1XRI A;  2NTA A;  2BV5 A;  3QCH A;  5K23 A;  3S3K A;  3D44 A;  1RPM A;  2HCM A;  4I8N A;  2IMG A;  3RZ2 A;  2Y96 A;  1C88 A;  2OZ5 A;  3RGO A;  3V0I A;  2CMB A;  3QCJ A;  1C86 A;  2G59 A;  1XBO A;  2QDC A;  4RKK A;  4ZRT A;  3S3H A;  2QEP A;  4S0G A;  2CFV A;  2Q05 A;  1BZC A;  4B04 A;  4R0T A;  3RO1 A;  1PTV A;  2CNE A;  3D1H A;  3ZMQ A;  2WGP A;  3NME A;  1G4U S;  3EZZ A;  2RF6 A;  2ESB A;  3BLT A;  4RI5 A;  2GJT A;  1T48 A;  3MOZ A;  4NND A;  2A3K A;  2QCT A;  1BZH A;  1G1H A;  4WU2 A;  1Q6S A;  2BGE A;  3QCE A;  4GS0 A;  2F6V A;  2I4E A;  2F6Y A;  2VEY A;  3AWG A;  3O5X A;  3RGQ A;  1RXD A;  4R0S A;  2I4H A;  4NX8 A;  4OHH A;  2BIJ A;  3OMH A;  3ZM0 A;  4GFV A;  1LAR A;  2HVL A;  1ZCK A;  2F6T A;  4RH5 A;  1FPR A;  1M3G A;  3M4U A;  2H4G A;  2H4K A;  2I6P A;  1C83 A;  4BPC A;  2B4O A;  3I7Z A;  2CM2 A;  4GFU A;  4JMK A;  2QBR A;  2FJM A;  2QBP A;  3QCK A;  3D1O A;  3F9A A;  1NO6 A;  4HJQ A;  2CM7 A;  1OHE A;  1GFY A;  1XXP A;  4RI4 A;  4ERC A;  1EEN A;  2CJZ A;  4IKC A;  2PSZ A;  1I9T A;  2ZN7 A;  2OC3 A;  5I6V A;  2I6I A;  4PYH A;  1PTT A;  3QCB A;  1FPZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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