5KA7A

Protein tyrosine phosphatase 1b t178a mutant in complex with tcs401, closed state
Total Genus 109
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
109
sequence length
298
structure length
298
Chain Sequence
SMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTAWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 109
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2016-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5ka7A00
1ZC0A 2I1YA 1RPMA 5IBSA 4RDDA 5KA7A 1OESA 2CJZA 2PBNA 3RZ2A 1A5YA 1YGRA 1T49A 2F6VA 2CM2A 3N0AA 3MOWA 3ZM1A 1PXHA 1V3AA 1U24A 3CM3A 1ZZWA 4GS0A 2F6YA 1G4WR 1U26A 4R30A 1MKPA 3SR9A 1G1GA 4BJOA 5KA3A 4R0SA 3MOZA 4WU3A 2B4SA 4WTYA 2FJNA 2QBPA 1X24A 5J8RA 2I42A 1LARA 3BRHA 5K25A 5M43A 4D3RA 5EHPA 4ICZA 4Y2EA 2H02A 3M4UA 3OLRA 3QKPA 1ECVA 3OMHA 3SMEA 1ONYA 2OOQA 1GWZA 2SHPA 4QUNA 3O4UA 2VEYA 3I80A 3GXGA 3S3FA 1XRIA 2H4KA 3V0GA 2JJDA 2F70A 3QKQA 2H4VA 4GRYA 5BX1A 5KA1A 3RGQA 1NZ7A 1JLNA 4JMJA 2CMBA 5KADA 2B4PA 3I7ZA 3QCFA 1BZJA 2I75A 3D42A 3ZV2A 1P15A 4QAPA 1JF7A 3F99A 2C46A 2BGDA 3S3HA 1PTUA 2BV5A 1FQ1A 3GXHA 1YWFA 2NT2A 5KA2A 4OHLA 2BZLA 2MBCA 1YTWA 4KI9A 3EB1A 1C83A 1OEMX 4DGXA 2B4OA 4KYQA 4QUMA 3F81A 2HXPA 1PA1A 3QCBA 1OHEA 2P4DA 4ZI4A 3LJ8A 4Z6BA 2CFVA 2CNFA 2QCTA 1PH0A 4YAAA 1OHDA 4OHIA 1KAKA 4HJPA 2VEWA 3QCCA 2PT0A 1GFYA 4ERCA 3O5XA 2NZ6A 2OUDA 2QBRA 1Q6MA 2I6OA 1LQFA 2AHSA 4NNDA 3O4SA 1QXKA 3U96A 3V0HA 2J16A 2BIJA 1XBOA 2RF6A 1YN9A 2F6TA 3S4OA 3A5JA 1YFOA 2Q05A 3F9AA 5K24A 2B07A 1OEUA 1I9SA 5MMZB 1C85A 3O4TA 4BPCA 3AWGA 2I4EA 1OEOX 1OHCA 4MBBA 4GFVA 4S0GA 2I3UA 4GE5A 2HC1A 4JBCA 1EEOA 2CNEA 4HRFA 2Q47A 5EHRA 2HNPA 2J17A 3D1OA 1XXPA 4GE6A 2QBSA 4PYHA 1M3GA 2B3OA 2HY3A 2NV5A 2OZ5A 2HCMA 4J51A 3O3LA 2CM3A 3D9CA 2CMCA 3B7OA 2QDPA 5KABA 2GWOA 1R6HA 3QCLA 2OC3A 1C88A 3ZMPA 1PTTA 4HJQA 2F6WA 5KAAA 3QCMA 1J4XA 5GTJA 4JMKA 2CMAA 2B4UA 1NNYA 2C7SA 5KACA 2QCJA 3S3EA 5I6VA 2A3KA 2GJTA 2QBQA 2VEVA 4RI4A 2B49A 3ZMQA 5K9VA 4YR8B 3V0DA 2QDMA 4IKCA 5KA8A 2Y2FA 4TVVA 1G7GA 1Q6JA 1SUGA 3V0FA 4GRZA 1QZ0A 3AWFA 2E0TA 3BLTA 1ONZA 1WAXA 2GP0A 4Y14A 2A8BA 2I6MA 1Q1MA 1G4US 1YTSA 4B04A 1G1FA 1ZCKA 4DGPA 4D3PA 1G1HA 1OETA 3EMUA 4I8NA 4KYRA 5HDEA 1L8GA 4OHEA 2H4GA 3QCDA 3ZM3A 1BZHA 4OHDA 4JNBA 3EU0A 1NWEA 2CM8A 4RHGA 1EENA 1NO6A 1C86A 4WOHA 1C87A 2I3RA 3RGOA 2HNQA 4QBEA 3QCGA 4NWGA 1AAXA 2IMGA 1YZ4A 2VEUA 2F71A 2AZRA 2I6IA 3AWEA 2H04A 4OHHA 1I57A 2ZN7A 1RXDA 1PYNA 2PA5A 2F46A 2NLKA 2PQ5A 2R0BA 5IBMA 5KA9A 5BZZA 1NWLA 2ESBA 5BUGA 2BGEA 2I6PA 2F6ZA 2NT7A 3ZM2A 2PSZA 1Q6TA 3D1QA 2NTAA 1YPTA 1FPRA 1LYVA 1ZCLA 1C84A 5BZXA 1OEVA 1T48A 4NYHA 1D5RA 1Q6NA 3QCKA 2CNIA 5KA4A 1FPZA 4GE2A 3ZM0A 2J16B 2PI7A 4H34A 4NWFA 4AZ1A 4GFUA 2WGPA 2H03A 2DXPA 2HVLA 3S4EA 1Q6PA 2ZMMA 5KA0A 1I9TA 1PTVA 3EAXA 3I36A 1YGUA 5K9WA 3QCIA 4QBWA 3RO1A 3V0EA 1NL9A 2I4HA 1PTYA 3QCNA 3MMJA 2CNHA 1YTNA 1G7FA 1KAVA 2FH7A 2Y96A 4WU2A 2G59A 1VHRA 3S3KA 1XXVA 4RH5A 5K23A 2I4GA 2M3VA 5AWXA 1WRMA 1PA9A 3NMEA 3PS5A 3CWEA 2HC2A 1Q6SA 3F41A 2VEXA 3A5KA 2P6XA 5LXQB 1L8KA 3V0IA 1XM2A 2QEPA 4QAHA 2HB1A 3H2XA 3QCEA 4NX8A 4ZRTA 5K22A 3QCHA 2CM7A 2I5XA 2F6FA 3BLUA 1T4JA 2I6JA 4PVGA 3F9BA 3QCJA 3BM8A 3D1HA 1WCHA 4R0TA 2CNGA 2G6ZA 2QDCA 2FJMA 2YDUA 4RI5A 4H1OA 3D44A 4D3QA 3EZZA 4GWFA 4ZN5A 3V0JA 4RKKA 4RH9A 1BZCA 1U25A
chains in the Genus database with same CATH superfamily
1ZC0A 2I1YA 1RPMA 3N2AA 5IBSA 4RDDA 5KA7A 1OESA 2CJZA 2PBNA 3RZ2A 1A5YA 1YGRA 1E0DA 1T49A 2F6VA 2CM2A 3N0AA 1GG4A 3MOWA 3ZM1A 1PXHA 1V3AA 1U24A 3CM3A 1ZZWA 4GS0A 2F6YA 1G4WR 1U26A 4R30A 1MKPA 3SR9A 1G1GA 4BJOA 5KA3A 4C13A 4R0SA 3MOZA 4WU3A 2B4SA 4WTYA 2FJNA 1GQQA 2QBPA 1X24A 5J8RA 2I42A 1LARA 3BRHA 5K25A 5M43A 4D3RA 5EHPA 4ICZA 4Y2EA 2H02A 2Y68A 3M4UA 3OLRA 3QKPA 1ECVA 3OMHA 3SMEA 3LK7A 1ONYA 2OOQA 1GWZA 2SHPA 2WJPA 4QUNA 3O4UA 2VEYA 3I80A 3GXGA 3S3FA 1XRIA 2H4KA 3V0GA 2JJDA 2F70A 3QKQA 2H4VA 4GRYA 5BX1A 5KA1A 3RGQA 1NZ7A 1JLNA 4JMJA 2CMBA 5KADA 2B4PA 3I7ZA 3QCFA 1BZJA 2I75A 3D42A 3ZV2A 3MVNA 1P15A 4QAPA 1JF7A 3F99A 2C46A 2BGDA 3S3HA 1PTUA 2BV5A 2JFFA 1FQ1A 3GXHA 1YWFA 2NT2A 5KA2A 4OHLA 2BZLA 2MBCA 1YTWA 2F00A 2VTDA 4KI9A 3EB1A 4QDIA 1C83A 1OEMX 4DGXA 2B4OA 4KYQA 4QUMA 3F81A 2HXPA 1PA1A 4CVMA 3QCBA 1OHEA 2P4DA 4ZI4A 3LJ8A 1J6UA 4Z6BA 5A5EA 2CFVA 2CNFA 2QCTA 1PH0A 4YAAA 1OHDA 4OHIA 1KAKA 4HJPA 2VEWA 3QCCA 2PT0A 1GFYA 4ERCA 3O5XA 2NZ6A 4HV4A 2OUDA 2QBRA 1Q6MA 2VOSA 2GCBA 2I6OA 1LQFA 2AHSA 4NNDA 3O4SA 1QXKA 2GCAA 3U96A 3V0HA 2J16A 2BIJA 1XBOA 2RF6A 1YN9A 2F6TA 3S4OA 3A5JA 1YFOA 2Q05A 3F9AA 5K24A 2Y67A 2B07A 2AM2A 1OEUA 1I9SA 5MMZB 1C85A 3O4TA 4BPCA 3AWGA 2I4EA 1OEOX 1OHCA 4UAGA 4MBBA 4GFVA 4S0GA 2I3UA 4GE5A 2HC1A 4JBCA 1EEOA 1P3DA 2CNEA 2VORA 4HRFA 2Q47A 5EHRA 2HNPA 2J17A 3D1OA 1XXPA 4GE6A 2QBSA 4PYHA 1M3GA 2B3OA 2GC6A 4BUBA 2HY3A 2NV5A 2OZ5A 2HCMA 4J51A 3O3LA 2CM3A 3D9CA 2CMCA 3B7OA 2QDPA 5KABA 4CVKA 2GWOA 1R6HA 3QCLA 4BUCA 2OC3A 1C88A 3ZMPA 1PTTA 4HJQA 2F6WA 5KAAA 3QCMA 1J4XA 5GTJA 4JMKA 2CMAA 2B4UA 1NNYA 2C7SA 5KACA 2QCJA 3S3EA 5I6VA 2A3KA 2GJTA 2QBQA 2VEVA 4RI4A 2B49A 3ZMQA 5K9VA 2GC5A 4YR8B 3V0DA 2QDMA 4IKCA 5KA8A 2Y2FA 4TVVA 1G7GA 1Q6JA 1SUGA 2XPCA 3V0FA 4GRZA 1QZ0A 3AWFA 2E0TA 3BLTA 2UUPA 1ONZA 1WAXA 2GP0A 4Y14A 2A8BA 2I6MA 1Q1MA 1G4US 1YTSA 3NRSA 4B04A 4QF5A 1G1FA 1O5ZA 1ZCKA 4DGPA 4D3PA 1G1HA 1OETA 3EMUA 4I8NA 4KYRA 5HDEA 1L8GA 4OHEA 2H4GA 3QCDA 3QCZA 3ZM3A 1BZHA 4OHDA 4JNBA 3EU0A 1NWEA 2CM8A 4RHGA 1EENA 1NO6A 1C86A 4WOHA 1C87A 1EEHA 2I3RA 3RGOA 2HNQA 4QBEA 3QCGA 4NWGA 1GQYA 1AAXA 2IMGA 1YZ4A 2VEUA 2F71A 2X5OA 2AZRA 2I6IA 3AWEA 2H04A 4OHHA 1I57A 2ZN7A 1RXDA 1PYNA 2PA5A 1W78A 2F46A 2NLKA 2PQ5A 2R0BA 5IBMA 5KA9A 4C12A 5BZZA 1NWLA 2ESBA 5BUGA 3PYZA 2BGEA 2I6PA 2F6ZA 2NT7A 3ZM2A 2PSZA 1Q6TA 2VTEA 3D1QA 2NTAA 1YPTA 1FPRA 1LYVA 1ZCLA 1C84A 5BZXA 1OEVA 1T48A 4NYHA 1D5RA 1Q6NA 2XJAA 3QCKA 2CNIA 2AM1A 4ZIYA 5KA4A 1FPZA 4GE2A 3ZM0A 2J16B 2PI7A 4CVLA 4H34A 4NWFA 4AZ1A 4GFUA 2WGPA 2H03A 2DXPA 2HVLA 3S4EA 1Q6PA 2ZMMA 5KA0A 1E8CA 1I9TA 1PTVA 3EAXA 3I36A 1YGUA 5K9WA 3QCIA 4QBWA 3RO1A 3V0EA 1NL9A 2I4HA 1PTYA 3QCNA 3MMJA 2CNHA 1YTNA 1G7FA 1KAVA 2FH7A 2Y96A 4WU2A 2G59A 1VHRA 5A5FA 3S3KA 1XXVA 4RH5A 5K23A 2UAGA 3ZL8A 2I4GA 2M3VA 2Y66A 2WTZA 1JBVA 5AWXA 3HN7A 1WRMA 1P31A 1PA9A 3NMEA 1W7KA 3PS5A 2JFGA 3CWEA 2HC2A 1Q6SA 3F41A 2VEXA 3A5KA 2P6XA 5LXQB 1L8KA 3V0IA 1UAGA 1XM2A 3UAGA 2QEPA 4QAHA 2HB1A 3H2XA 3QCEA 4NX8A 4ZRTA 5K22A 1FGSA 3QCHA 2CM7A 2I5XA 2F6FA 3BLUA 1T4JA 2I6JA 4PVGA 3F9BA 3QCJA 1JBWA 2Y1OA 3BM8A 3D1HA 1WCHA 4R0TA 2CNGA 2G6ZA 2QDCA 2FJMA 3ZM5A 2YDUA 4RI5A 4H1OA 3D44A 4D3QA 2JFHA 3EZZA 4GWFA 4ZN5A 3V0JA 2UUOA 3ZM6A 4RKKA 4RH9A 1BZCA 1U25A
chains in the Genus database with same CATH topology
1ZC0A 2I1YA 1RPMA 5IBSA 4RDDA 5KA7A 1OESA 2CJZA 2PBNA 3RZ2A 1A5YA 1YGRA 1T49A 2F6VA 2CM2A 3N0AA 3MOWA 3ZM1A 1PXHA 1V3AA 1U24A 3CM3A 1ZZWA 4GS0A 2F6YA 1G4WR 1U26A 4R30A 1MKPA 3SR9A 1G1GA 4BJOA 5KA3A 4R0SA 3MOZA 4WU3A 2B4SA 4WTYA 2FJNA 2QBPA 1X24A 5J8RA 2I42A 1LARA 3BRHA 5K25A 5M43A 4D3RA 5EHPA 4ICZA 4Y2EA 2H02A 3M4UA 3OLRA 3QKPA 1ECVA 3OMHA 3SMEA 1ONYA 2OOQA 1GWZA 2SHPA 4QUNA 3O4UA 2VEYA 3I80A 3GXGA 3S3FA 1XRIA 2H4KA 3V0GA 2JJDA 2F70A 3QKQA 2H4VA 4GRYA 5BX1A 5KA1A 3RGQA 1NZ7A 1JLNA 4JMJA 2CMBA 5KADA 2B4PA 3I7ZA 3QCFA 1BZJA 2I75A 3D42A 3ZV2A 1P15A 4QAPA 1JF7A 3F99A 2C46A 2BGDA 3S3HA 1PTUA 2BV5A 1FQ1A 3GXHA 1YWFA 2NT2A 5KA2A 4OHLA 2BZLA 2MBCA 1YTWA 4KI9A 3EB1A 1C83A 1OEMX 4DGXA 2B4OA 4KYQA 4QUMA 3F81A 2HXPA 1PA1A 3QCBA 1OHEA 2P4DA 4ZI4A 3LJ8A 4Z6BA 2CFVA 2CNFA 2QCTA 1PH0A 4YAAA 1OHDA 4OHIA 1KAKA 4HJPA 2VEWA 3QCCA 2PT0A 1GFYA 4ERCA 3O5XA 2NZ6A 2OUDA 2QBRA 1Q6MA 2I6OA 1LQFA 2AHSA 4NNDA 3O4SA 1QXKA 3U96A 3V0HA 2J16A 2BIJA 1XBOA 2RF6A 1YN9A 2F6TA 3S4OA 3A5JA 1YFOA 2Q05A 3F9AA 5K24A 2B07A 1OEUA 1I9SA 5MMZB 1C85A 3O4TA 4BPCA 3AWGA 2I4EA 1OEOX 1OHCA 4MBBA 4GFVA 4S0GA 2I3UA 4GE5A 2HC1A 4JBCA 1EEOA 2CNEA 4HRFA 2Q47A 5EHRA 2HNPA 2J17A 3D1OA 1XXPA 4GE6A 2QBSA 4PYHA 1M3GA 2B3OA 2HY3A 2NV5A 2OZ5A 2HCMA 4J51A 3O3LA 2CM3A 3D9CA 2CMCA 3B7OA 2QDPA 5KABA 2GWOA 1R6HA 3QCLA 2OC3A 1C88A 3ZMPA 1PTTA 4HJQA 2F6WA 5KAAA 3QCMA 1J4XA 5GTJA 4JMKA 2CMAA 2B4UA 1NNYA 2C7SA 5KACA 2QCJA 3S3EA 5I6VA 2A3KA 2GJTA 2QBQA 2VEVA 4RI4A 2B49A 3ZMQA 5K9VA 4YR8B 3V0DA 2QDMA 4IKCA 5KA8A 2Y2FA 4TVVA 1G7GA 1Q6JA 1SUGA 3V0FA 4GRZA 1QZ0A 3AWFA 2E0TA 3BLTA 1ONZA 1WAXA 2GP0A 4Y14A 2A8BA 2I6MA 1Q1MA 1G4US 1YTSA 4B04A 1G1FA 1ZCKA 4DGPA 4D3PA 1G1HA 1OETA 3EMUA 4I8NA 4KYRA 5HDEA 1L8GA 4OHEA 2H4GA 3QCDA 3ZM3A 1BZHA 4OHDA 4JNBA 3EU0A 1NWEA 2CM8A 4RHGA 1EENA 1NO6A 1C86A 4WOHA 1C87A 2I3RA 3RGOA 2HNQA 4QBEA 3QCGA 4NWGA 1AAXA 2IMGA 1YZ4A 2VEUA 2F71A 2AZRA 2I6IA 3AWEA 2H04A 4OHHA 1I57A 2ZN7A 1RXDA 1PYNA 2PA5A 2F46A 2NLKA 2PQ5A 2R0BA 5IBMA 5KA9A 5BZZA 1NWLA 2ESBA 5BUGA 2BGEA 2I6PA 2F6ZA 2NT7A 3ZM2A 2PSZA 1Q6TA 3D1QA 2NTAA 1YPTA 1FPRA 1LYVA 1ZCLA 1C84A 5BZXA 1OEVA 1T48A 4NYHA 1D5RA 1Q6NA 3QCKA 2CNIA 5KA4A 1FPZA 4GE2A 3ZM0A 2J16B 2PI7A 4H34A 4NWFA 4AZ1A 4GFUA 2WGPA 2H03A 2DXPA 2HVLA 3S4EA 1Q6PA 2ZMMA 5KA0A 1I9TA 1PTVA 3EAXA 3I36A 1YGUA 5K9WA 3QCIA 4QBWA 3RO1A 3V0EA 1NL9A 2I4HA 1PTYA 3QCNA 3MMJA 2CNHA 1YTNA 1G7FA 1KAVA 2FH7A 2Y96A 4WU2A 2G59A 1VHRA 3S3KA 1XXVA 4RH5A 5K23A 2I4GA 2M3VA 5AWXA 1WRMA 1PA9A 3NMEA 3PS5A 3CWEA 2HC2A 1Q6SA 3F41A 2VEXA 3A5KA 2P6XA 5LXQB 1L8KA 3V0IA 1XM2A 2QEPA 4QAHA 2HB1A 3H2XA 3QCEA 4NX8A 4ZRTA 5K22A 3QCHA 2CM7A 2I5XA 2F6FA 3BLUA 1T4JA 2I6JA 4PVGA 3F9BA 3QCJA 3BM8A 3D1HA 1WCHA 4R0TA 2CNGA 2G6ZA 2QDCA 2FJMA 2YDUA 4RI5A 4H1OA 3D44A 4D3QA 3EZZA 4GWFA 4ZN5A 3V0JA 4RKKA 4RH9A 1BZCA 1U25A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZC0 A;  2I1Y A;  1RPM A;  5IBS A;  4RDD A;  5KA7 A;  1OES A;  2CJZ A;  2PBN A;  3RZ2 A;  1A5Y A;  1YGR A;  1T49 A;  2F6V A;  2CM2 A;  3N0A A;  3MOW A;  3ZM1 A;  1PXH A;  1V3A A;  1U24 A;  3CM3 A;  1ZZW A;  4GS0 A;  2F6Y A;  1G4W R;  1U26 A;  4R30 A;  1MKP A;  3SR9 A;  1G1G A;  4BJO A;  5KA3 A;  4R0S A;  3MOZ A;  4WU3 A;  2B4S A;  4WTY A;  2FJN A;  2QBP A;  1X24 A;  5J8R A;  2I42 A;  1LAR A;  3BRH A;  5K25 A;  5M43 A;  4D3R A;  5EHP A;  4ICZ A;  4Y2E A;  2H02 A;  3M4U A;  3OLR A;  3QKP A;  1ECV A;  3OMH A;  3SME A;  1ONY A;  2OOQ A;  1GWZ A;  2SHP A;  4QUN A;  3O4U A;  2VEY A;  3I80 A;  3GXG A;  3S3F A;  1XRI A;  2H4K A;  3V0G A;  2JJD A;  2F70 A;  3QKQ A;  2H4V A;  4GRY A;  5BX1 A;  5KA1 A;  3RGQ A;  1NZ7 A;  1JLN A;  4JMJ A;  2CMB A;  5KAD A;  2B4P A;  3I7Z A;  3QCF A;  1BZJ A;  2I75 A;  3D42 A;  3ZV2 A;  1P15 A;  4QAP A;  1JF7 A;  3F99 A;  2C46 A;  2BGD A;  3S3H A;  1PTU A;  2BV5 A;  1FQ1 A;  3GXH A;  1YWF A;  2NT2 A;  5KA2 A;  4OHL A;  2BZL A;  2MBC A;  1YTW A;  4KI9 A;  3EB1 A;  1C83 A;  1OEM X;  4DGX A;  2B4O A;  4KYQ A;  4QUM A;  3F81 A;  2HXP A;  1PA1 A;  3QCB A;  1OHE A;  2P4D A;  4ZI4 A;  3LJ8 A;  4Z6B A;  2CFV A;  2CNF A;  2QCT A;  1PH0 A;  4YAA A;  1OHD A;  4OHI A;  1KAK A;  4HJP A;  2VEW A;  3QCC A;  2PT0 A;  1GFY A;  4ERC A;  3O5X A;  2NZ6 A;  2OUD A;  2QBR A;  1Q6M A;  2I6O A;  1LQF A;  2AHS A;  4NND A;  3O4S A;  1QXK A;  3U96 A;  3V0H A;  2J16 A;  2BIJ A;  1XBO A;  2RF6 A;  1YN9 A;  2F6T A;  3S4O A;  3A5J A;  1YFO A;  2Q05 A;  3F9A A;  5K24 A;  2B07 A;  1OEU A;  1I9S A;  5MMZ B;  1C85 A;  3O4T A;  4BPC A;  3AWG A;  2I4E A;  1OEO X;  1OHC A;  4MBB A;  4GFV A;  4S0G A;  2I3U A;  4GE5 A;  2HC1 A;  4JBC A;  1EEO A;  2CNE A;  4HRF A;  2Q47 A;  5EHR A;  2HNP A;  2J17 A;  3D1O A;  1XXP A;  4GE6 A;  2QBS A;  4PYH A;  1M3G A;  2B3O A;  2HY3 A;  2NV5 A;  2OZ5 A;  2HCM A;  4J51 A;  3O3L A;  2CM3 A;  3D9C A;  2CMC A;  3B7O A;  2QDP A;  5KAB A;  2GWO A;  1R6H A;  3QCL A;  2OC3 A;  1C88 A;  3ZMP A;  1PTT A;  4HJQ A;  2F6W A;  5KAA A;  3QCM A;  1J4X A;  5GTJ A;  4JMK A;  2CMA A;  2B4U A;  1NNY A;  2C7S A;  5KAC A;  2QCJ A;  3S3E A;  5I6V A;  2A3K A;  2GJT A;  2QBQ A;  2VEV A;  4RI4 A;  2B49 A;  3ZMQ A;  5K9V A;  4YR8 B;  3V0D A;  2QDM A;  4IKC A;  5KA8 A;  2Y2F A;  4TVV A;  1G7G A;  1Q6J A;  1SUG A;  3V0F A;  4GRZ A;  1QZ0 A;  3AWF A;  2E0T A;  3BLT A;  1ONZ A;  1WAX A;  2GP0 A;  4Y14 A;  2A8B A;  2I6M A;  1Q1M A;  1G4U S;  1YTS A;  4B04 A;  1G1F A;  1ZCK A;  4DGP A;  4D3P A;  1G1H A;  1OET A;  3EMU A;  4I8N A;  4KYR A;  5HDE A;  1L8G A;  4OHE A;  2H4G A;  3QCD A;  3ZM3 A;  1BZH A;  4OHD A;  4JNB A;  3EU0 A;  1NWE A;  2CM8 A;  4RHG A;  1EEN A;  1NO6 A;  1C86 A;  4WOH A;  1C87 A;  2I3R A;  3RGO A;  2HNQ A;  4QBE A;  3QCG A;  4NWG A;  1AAX A;  2IMG A;  1YZ4 A;  2VEU A;  2F71 A;  2AZR A;  2I6I A;  3AWE A;  2H04 A;  4OHH A;  1I57 A;  2ZN7 A;  1RXD A;  1PYN A;  2PA5 A;  2F46 A;  2NLK A;  2PQ5 A;  2R0B A;  5IBM A;  5KA9 A;  5BZZ A;  1NWL A;  2ESB A;  5BUG A;  2BGE A;  2I6P A;  2F6Z A;  2NT7 A;  3ZM2 A;  2PSZ A;  1Q6T A;  3D1Q A;  2NTA A;  1YPT A;  1FPR A;  1LYV A;  1ZCL A;  1C84 A;  5BZX A;  1OEV A;  1T48 A;  4NYH A;  1D5R A;  1Q6N A;  3QCK A;  2CNI A;  5KA4 A;  1FPZ A;  4GE2 A;  3ZM0 A;  2J16 B;  2PI7 A;  4H34 A;  4NWF A;  4AZ1 A;  4GFU A;  2WGP A;  2H03 A;  2DXP A;  2HVL A;  3S4E A;  1Q6P A;  2ZMM A;  5KA0 A;  1I9T A;  1PTV A;  3EAX A;  3I36 A;  1YGU A;  5K9W A;  3QCI A;  4QBW A;  3RO1 A;  3V0E A;  1NL9 A;  2I4H A;  1PTY A;  3QCN A;  3MMJ A;  2CNH A;  1YTN A;  1G7F A;  1KAV A;  2FH7 A;  2Y96 A;  4WU2 A;  2G59 A;  1VHR A;  3S3K A;  1XXV A;  4RH5 A;  5K23 A;  2I4G A;  2M3V A;  5AWX A;  1WRM A;  1PA9 A;  3NME A;  3PS5 A;  3CWE A;  2HC2 A;  1Q6S A;  3F41 A;  2VEX A;  3A5K A;  2P6X A;  5LXQ B;  1L8K A;  3V0I A;  1XM2 A;  2QEP A;  4QAH A;  2HB1 A;  3H2X A;  3QCE A;  4NX8 A;  4ZRT A;  5K22 A;  3QCH A;  2CM7 A;  2I5X A;  2F6F A;  3BLU A;  1T4J A;  2I6J A;  4PVG A;  3F9B A;  3QCJ A;  3BM8 A;  3D1H A;  1WCH A;  4R0T A;  2CNG A;  2G6Z A;  2QDC A;  2FJM A;  2YDU A;  4RI5 A;  4H1O A;  3D44 A;  4D3Q A;  3EZZ A;  4GWF A;  4ZN5 A;  3V0J A;  4RKK A;  4RH9 A;  1BZC A;  1U25 A; 
#chains in the Genus database with same CATH topology
 1ZC0 A;  2I1Y A;  1RPM A;  3N2A A;  5IBS A;  4RDD A;  5KA7 A;  1OES A;  2CJZ A;  2PBN A;  3RZ2 A;  1A5Y A;  1YGR A;  1E0D A;  1T49 A;  2F6V A;  2CM2 A;  3N0A A;  1GG4 A;  3MOW A;  3ZM1 A;  1PXH A;  1V3A A;  1U24 A;  3CM3 A;  1ZZW A;  4GS0 A;  2F6Y A;  1G4W R;  1U26 A;  4R30 A;  1MKP A;  3SR9 A;  1G1G A;  4BJO A;  5KA3 A;  4C13 A;  4R0S A;  3MOZ A;  4WU3 A;  2B4S A;  4WTY A;  2FJN A;  1GQQ A;  2QBP A;  1X24 A;  5J8R A;  2I42 A;  1LAR A;  3BRH A;  5K25 A;  5M43 A;  4D3R A;  5EHP A;  4ICZ A;  4Y2E A;  2H02 A;  2Y68 A;  3M4U A;  3OLR A;  3QKP A;  1ECV A;  3OMH A;  3SME A;  3LK7 A;  1ONY A;  2OOQ A;  1GWZ A;  2SHP A;  2WJP A;  4QUN A;  3O4U A;  2VEY A;  3I80 A;  3GXG A;  3S3F A;  1XRI A;  2H4K A;  3V0G A;  2JJD A;  2F70 A;  3QKQ A;  2H4V A;  4GRY A;  5BX1 A;  5KA1 A;  3RGQ A;  1NZ7 A;  1JLN A;  4JMJ A;  2CMB A;  5KAD A;  2B4P A;  3I7Z A;  3QCF A;  1BZJ A;  2I75 A;  3D42 A;  3ZV2 A;  3MVN A;  1P15 A;  4QAP A;  1JF7 A;  3F99 A;  2C46 A;  2BGD A;  3S3H A;  1PTU A;  2BV5 A;  2JFF A;  1FQ1 A;  3GXH A;  1YWF A;  2NT2 A;  5KA2 A;  4OHL A;  2BZL A;  2MBC A;  1YTW A;  2F00 A;  2VTD A;  4KI9 A;  3EB1 A;  4QDI A;  1C83 A;  1OEM X;  4DGX A;  2B4O A;  4KYQ A;  4QUM A;  3F81 A;  2HXP A;  1PA1 A;  4CVM A;  3QCB A;  1OHE A;  2P4D A;  4ZI4 A;  3LJ8 A;  1J6U A;  4Z6B A;  5A5E A;  2CFV A;  2CNF A;  2QCT A;  1PH0 A;  4YAA A;  1OHD A;  4OHI A;  1KAK A;  4HJP A;  2VEW A;  3QCC A;  2PT0 A;  1GFY A;  4ERC A;  3O5X A;  2NZ6 A;  4HV4 A;  2OUD A;  2QBR A;  1Q6M A;  2VOS A;  2GCB A;  2I6O A;  1LQF A;  2AHS A;  4NND A;  3O4S A;  1QXK A;  2GCA A;  3U96 A;  3V0H A;  2J16 A;  2BIJ A;  1XBO A;  2RF6 A;  1YN9 A;  2F6T A;  3S4O A;  3A5J A;  1YFO A;  2Q05 A;  3F9A A;  5K24 A;  2Y67 A;  2B07 A;  2AM2 A;  1OEU A;  1I9S A;  5MMZ B;  1C85 A;  3O4T A;  4BPC A;  3AWG A;  2I4E A;  1OEO X;  1OHC A;  4UAG A;  4MBB A;  4GFV A;  4S0G A;  2I3U A;  4GE5 A;  2HC1 A;  4JBC A;  1EEO A;  1P3D A;  2CNE A;  2VOR A;  4HRF A;  2Q47 A;  5EHR A;  2HNP A;  2J17 A;  3D1O A;  1XXP A;  4GE6 A;  2QBS A;  4PYH A;  1M3G A;  2B3O A;  2GC6 A;  4BUB A;  2HY3 A;  2NV5 A;  2OZ5 A;  2HCM A;  4J51 A;  3O3L A;  2CM3 A;  3D9C A;  2CMC A;  3B7O A;  2QDP A;  5KAB A;  4CVK A;  2GWO A;  1R6H A;  3QCL A;  4BUC A;  2OC3 A;  1C88 A;  3ZMP A;  1PTT A;  4HJQ A;  2F6W A;  5KAA A;  3QCM A;  1J4X A;  5GTJ A;  4JMK A;  2CMA A;  2B4U A;  1NNY A;  2C7S A;  5KAC A;  2QCJ A;  3S3E A;  5I6V A;  2A3K A;  2GJT A;  2QBQ A;  2VEV A;  4RI4 A;  2B49 A;  3ZMQ A;  5K9V A;  2GC5 A;  4YR8 B;  3V0D A;  2QDM A;  4IKC A;  5KA8 A;  2Y2F A;  4TVV A;  1G7G A;  1Q6J A;  1SUG A;  2XPC A;  3V0F A;  4GRZ A;  1QZ0 A;  3AWF A;  2E0T A;  3BLT A;  2UUP A;  1ONZ A;  1WAX A;  2GP0 A;  4Y14 A;  2A8B A;  2I6M A;  1Q1M A;  1G4U S;  1YTS A;  3NRS A;  4B04 A;  4QF5 A;  1G1F A;  1O5Z A;  1ZCK A;  4DGP A;  4D3P A;  1G1H A;  1OET A;  3EMU A;  4I8N A;  4KYR A;  5HDE A;  1L8G A;  4OHE A;  2H4G A;  3QCD A;  3QCZ A;  3ZM3 A;  1BZH A;  4OHD A;  4JNB A;  3EU0 A;  1NWE A;  2CM8 A;  4RHG A;  1EEN A;  1NO6 A;  1C86 A;  4WOH A;  1C87 A;  1EEH A;  2I3R A;  3RGO A;  2HNQ A;  4QBE A;  3QCG A;  4NWG A;  1GQY A;  1AAX A;  2IMG A;  1YZ4 A;  2VEU A;  2F71 A;  2X5O A;  2AZR A;  2I6I A;  3AWE A;  2H04 A;  4OHH A;  1I57 A;  2ZN7 A;  1RXD A;  1PYN A;  2PA5 A;  1W78 A;  2F46 A;  2NLK A;  2PQ5 A;  2R0B A;  5IBM A;  5KA9 A;  4C12 A;  5BZZ A;  1NWL A;  2ESB A;  5BUG A;  3PYZ A;  2BGE A;  2I6P A;  2F6Z A;  2NT7 A;  3ZM2 A;  2PSZ A;  1Q6T A;  2VTE A;  3D1Q A;  2NTA A;  1YPT A;  1FPR A;  1LYV A;  1ZCL A;  1C84 A;  5BZX A;  1OEV A;  1T48 A;  4NYH A;  1D5R A;  1Q6N A;  2XJA A;  3QCK A;  2CNI A;  2AM1 A;  4ZIY A;  5KA4 A;  1FPZ A;  4GE2 A;  3ZM0 A;  2J16 B;  2PI7 A;  4CVL A;  4H34 A;  4NWF A;  4AZ1 A;  4GFU A;  2WGP A;  2H03 A;  2DXP A;  2HVL A;  3S4E A;  1Q6P A;  2ZMM A;  5KA0 A;  1E8C A;  1I9T A;  1PTV A;  3EAX A;  3I36 A;  1YGU A;  5K9W A;  3QCI A;  4QBW A;  3RO1 A;  3V0E A;  1NL9 A;  2I4H A;  1PTY A;  3QCN A;  3MMJ A;  2CNH A;  1YTN A;  1G7F A;  1KAV A;  2FH7 A;  2Y96 A;  4WU2 A;  2G59 A;  1VHR A;  5A5F A;  3S3K A;  1XXV A;  4RH5 A;  5K23 A;  2UAG A;  3ZL8 A;  2I4G A;  2M3V A;  2Y66 A;  2WTZ A;  1JBV A;  5AWX A;  3HN7 A;  1WRM A;  1P31 A;  1PA9 A;  3NME A;  1W7K A;  3PS5 A;  2JFG A;  3CWE A;  2HC2 A;  1Q6S A;  3F41 A;  2VEX A;  3A5K A;  2P6X A;  5LXQ B;  1L8K A;  3V0I A;  1UAG A;  1XM2 A;  3UAG A;  2QEP A;  4QAH A;  2HB1 A;  3H2X A;  3QCE A;  4NX8 A;  4ZRT A;  5K22 A;  1FGS A;  3QCH A;  2CM7 A;  2I5X A;  2F6F A;  3BLU A;  1T4J A;  2I6J A;  4PVG A;  3F9B A;  3QCJ A;  1JBW A;  2Y1O A;  3BM8 A;  3D1H A;  1WCH A;  4R0T A;  2CNG A;  2G6Z A;  2QDC A;  2FJM A;  3ZM5 A;  2YDU A;  4RI5 A;  4H1O A;  3D44 A;  4D3Q A;  2JFH A;  3EZZ A;  4GWF A;  4ZN5 A;  3V0J A;  2UUO A;  3ZM6 A;  4RKK A;  4RH9 A;  1BZC A;  1U25 A; 
#chains in the Genus database with same CATH homology
 1ZC0 A;  2I1Y A;  1RPM A;  5IBS A;  4RDD A;  5KA7 A;  1OES A;  2CJZ A;  2PBN A;  3RZ2 A;  1A5Y A;  1YGR A;  1T49 A;  2F6V A;  2CM2 A;  3N0A A;  3MOW A;  3ZM1 A;  1PXH A;  1V3A A;  1U24 A;  3CM3 A;  1ZZW A;  4GS0 A;  2F6Y A;  1G4W R;  1U26 A;  4R30 A;  1MKP A;  3SR9 A;  1G1G A;  4BJO A;  5KA3 A;  4R0S A;  3MOZ A;  4WU3 A;  2B4S A;  4WTY A;  2FJN A;  2QBP A;  1X24 A;  5J8R A;  2I42 A;  1LAR A;  3BRH A;  5K25 A;  5M43 A;  4D3R A;  5EHP A;  4ICZ A;  4Y2E A;  2H02 A;  3M4U A;  3OLR A;  3QKP A;  1ECV A;  3OMH A;  3SME A;  1ONY A;  2OOQ A;  1GWZ A;  2SHP A;  4QUN A;  3O4U A;  2VEY A;  3I80 A;  3GXG A;  3S3F A;  1XRI A;  2H4K A;  3V0G A;  2JJD A;  2F70 A;  3QKQ A;  2H4V A;  4GRY A;  5BX1 A;  5KA1 A;  3RGQ A;  1NZ7 A;  1JLN A;  4JMJ A;  2CMB A;  5KAD A;  2B4P A;  3I7Z A;  3QCF A;  1BZJ A;  2I75 A;  3D42 A;  3ZV2 A;  1P15 A;  4QAP A;  1JF7 A;  3F99 A;  2C46 A;  2BGD A;  3S3H A;  1PTU A;  2BV5 A;  1FQ1 A;  3GXH A;  1YWF A;  2NT2 A;  5KA2 A;  4OHL A;  2BZL A;  2MBC A;  1YTW A;  4KI9 A;  3EB1 A;  1C83 A;  1OEM X;  4DGX A;  2B4O A;  4KYQ A;  4QUM A;  3F81 A;  2HXP A;  1PA1 A;  3QCB A;  1OHE A;  2P4D A;  4ZI4 A;  3LJ8 A;  4Z6B A;  2CFV A;  2CNF A;  2QCT A;  1PH0 A;  4YAA A;  1OHD A;  4OHI A;  1KAK A;  4HJP A;  2VEW A;  3QCC A;  2PT0 A;  1GFY A;  4ERC A;  3O5X A;  2NZ6 A;  2OUD A;  2QBR A;  1Q6M A;  2I6O A;  1LQF A;  2AHS A;  4NND A;  3O4S A;  1QXK A;  3U96 A;  3V0H A;  2J16 A;  2BIJ A;  1XBO A;  2RF6 A;  1YN9 A;  2F6T A;  3S4O A;  3A5J A;  1YFO A;  2Q05 A;  3F9A A;  5K24 A;  2B07 A;  1OEU A;  1I9S A;  5MMZ B;  1C85 A;  3O4T A;  4BPC A;  3AWG A;  2I4E A;  1OEO X;  1OHC A;  4MBB A;  4GFV A;  4S0G A;  2I3U A;  4GE5 A;  2HC1 A;  4JBC A;  1EEO A;  2CNE A;  4HRF A;  2Q47 A;  5EHR A;  2HNP A;  2J17 A;  3D1O A;  1XXP A;  4GE6 A;  2QBS A;  4PYH A;  1M3G A;  2B3O A;  2HY3 A;  2NV5 A;  2OZ5 A;  2HCM A;  4J51 A;  3O3L A;  2CM3 A;  3D9C A;  2CMC A;  3B7O A;  2QDP A;  5KAB A;  2GWO A;  1R6H A;  3QCL A;  2OC3 A;  1C88 A;  3ZMP A;  1PTT A;  4HJQ A;  2F6W A;  5KAA A;  3QCM A;  1J4X A;  5GTJ A;  4JMK A;  2CMA A;  2B4U A;  1NNY A;  2C7S A;  5KAC A;  2QCJ A;  3S3E A;  5I6V A;  2A3K A;  2GJT A;  2QBQ A;  2VEV A;  4RI4 A;  2B49 A;  3ZMQ A;  5K9V A;  4YR8 B;  3V0D A;  2QDM A;  4IKC A;  5KA8 A;  2Y2F A;  4TVV A;  1G7G A;  1Q6J A;  1SUG A;  3V0F A;  4GRZ A;  1QZ0 A;  3AWF A;  2E0T A;  3BLT A;  1ONZ A;  1WAX A;  2GP0 A;  4Y14 A;  2A8B A;  2I6M A;  1Q1M A;  1G4U S;  1YTS A;  4B04 A;  1G1F A;  1ZCK A;  4DGP A;  4D3P A;  1G1H A;  1OET A;  3EMU A;  4I8N A;  4KYR A;  5HDE A;  1L8G A;  4OHE A;  2H4G A;  3QCD A;  3ZM3 A;  1BZH A;  4OHD A;  4JNB A;  3EU0 A;  1NWE A;  2CM8 A;  4RHG A;  1EEN A;  1NO6 A;  1C86 A;  4WOH A;  1C87 A;  2I3R A;  3RGO A;  2HNQ A;  4QBE A;  3QCG A;  4NWG A;  1AAX A;  2IMG A;  1YZ4 A;  2VEU A;  2F71 A;  2AZR A;  2I6I A;  3AWE A;  2H04 A;  4OHH A;  1I57 A;  2ZN7 A;  1RXD A;  1PYN A;  2PA5 A;  2F46 A;  2NLK A;  2PQ5 A;  2R0B A;  5IBM A;  5KA9 A;  5BZZ A;  1NWL A;  2ESB A;  5BUG A;  2BGE A;  2I6P A;  2F6Z A;  2NT7 A;  3ZM2 A;  2PSZ A;  1Q6T A;  3D1Q A;  2NTA A;  1YPT A;  1FPR A;  1LYV A;  1ZCL A;  1C84 A;  5BZX A;  1OEV A;  1T48 A;  4NYH A;  1D5R A;  1Q6N A;  3QCK A;  2CNI A;  5KA4 A;  1FPZ A;  4GE2 A;  3ZM0 A;  2J16 B;  2PI7 A;  4H34 A;  4NWF A;  4AZ1 A;  4GFU A;  2WGP A;  2H03 A;  2DXP A;  2HVL A;  3S4E A;  1Q6P A;  2ZMM A;  5KA0 A;  1I9T A;  1PTV A;  3EAX A;  3I36 A;  1YGU A;  5K9W A;  3QCI A;  4QBW A;  3RO1 A;  3V0E A;  1NL9 A;  2I4H A;  1PTY A;  3QCN A;  3MMJ A;  2CNH A;  1YTN A;  1G7F A;  1KAV A;  2FH7 A;  2Y96 A;  4WU2 A;  2G59 A;  1VHR A;  3S3K A;  1XXV A;  4RH5 A;  5K23 A;  2I4G A;  2M3V A;  5AWX A;  1WRM A;  1PA9 A;  3NME A;  3PS5 A;  3CWE A;  2HC2 A;  1Q6S A;  3F41 A;  2VEX A;  3A5K A;  2P6X A;  5LXQ B;  1L8K A;  3V0I A;  1XM2 A;  2QEP A;  4QAH A;  2HB1 A;  3H2X A;  3QCE A;  4NX8 A;  4ZRT A;  5K22 A;  3QCH A;  2CM7 A;  2I5X A;  2F6F A;  3BLU A;  1T4J A;  2I6J A;  4PVG A;  3F9B A;  3QCJ A;  3BM8 A;  3D1H A;  1WCH A;  4R0T A;  2CNG A;  2G6Z A;  2QDC A;  2FJM A;  2YDU A;  4RI5 A;  4H1O A;  3D44 A;  4D3Q A;  3EZZ A;  4GWF A;  4ZN5 A;  3V0J A;  4RKK A;  4RH9 A;  1BZC A;  1U25 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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