3EZZA

Crystal structure of human mkp-2
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
144
structure length
144
Chain Sequence
MGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHSQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the catalytic domain of human MKP-2 reveals a 24-mer assembly.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Dual specificity protein phosphatase 4
total genus 53
structure length 144
sequence length 144
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2008-10-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 3ezzA00
2H03A 4PYHA 5MMZB 3O3LA 2FH7A 1V3AA 2HC2A 1C86A 1L8KA 1C83A 4BPCA 4RH9A 2PA5A 1YPTA 4QBWA 4QBEA 2NV5A 1ONZA 4GFUA 1Q6JA 4GE6A 1GFYA 2I6OA 3O4SA 1WCHA 3QCDA 4D3QA 1G1GA 2VEXA 3S3FA 3RO1A 1PTYA 3F41A 1JLNA 3QKPA 2YDUA 3ZM0A 2AHSA 1X24A 5KA0A 1MKPA 3ZMPA 2HVLA 4RI4A 2F6TA 4D3PA 3GXHA 2VEUA 4JBCA 1EENA 1G7FA 1C84A 4OHIA 5KA9A 2I4HA 5EHRA 3SR9A 2PBNA 2AZRA 3F99A 2BGDA 1NWEA 3QCCA 4GE5A 3QCBA 2CJZA 2OC3A 2QBRA 4NWFA 3V0FA 1XRIA 4R0SA 1D5RA 3QCIA 1BZCA 4R30A 1U24A 2I5XA 1T4JA 2B4OA 2QCJA 4OHEA 5BUGA 2QDCA 2F70A 2B4PA 5K25A 2JJDA 3MOZA 2H02A 1XM2A 4ICZA 2P4DA 3V0EA 3O4UA 2BIJA 3M4UA 4TVVA 5KA7A 4OHHA 3EB1A 2P6XA 4ZRTA 5KADA 3S3EA 2E0TA 3BLUA 4H34A 5KACA 2CMAA 4GRZA 2J16A 1QZ0A 1BZJA 1FPZA 1XXPA 2ZMMA 1Q6SA 3AWFA 5K22A 1OHEA 1G1HA 3U96A 4NNDA 1ONYA 2B3OA 4RDDA 2VEVA 5KA2A 2QBSA 5IBMA 1NWLA 1YGUA 3EU0A 1PTTA 4YR8B 3QCHA 3D42A 4OHLA 2F46A 5KA1A 4GRYA 2I4EA 3D44A 2WGPA 1U26A 2J16B 1PTVA 1Q6PA 1FPRA 3QKQA 4RKKA 1L8GA 3D1QA 1WRMA 4AZ1A 3I7ZA 3V0GA 1R6HA 1XBOA 4RH5A 1YGRA 3V0HA 2VEYA 2CNGA 2CNHA 4HJPA 5BZZA 4Y14A 3O4TA 3ZV2A 4WU2A 2ZN7A 3GXGA 2MBCA 2QBPA 3RZ2A 3QCNA 2Q47A 5K9VA 1T49A 2A8BA 2H4KA 4D3RA 1G7GA 4GE2A 1NL9A 2BV5A 2QCTA 4BJOA 4HRFA 2F6YA 2F6ZA 1YTNA 3A5KA 3OMHA 2NT2A 1KAVA 2CM7A 1YTSA 2CNIA 3F81A 4PVGA 2M3VA 2NT7A 3CM3A 1ZCLA 3O5XA 3D9CA 1NZ7A 3OLRA 4GS0A 1OHDA 1ZZWA 2DXPA 2NZ6A 3A5JA 4NWGA 2B4SA 4J51A 1Q6TA 1QXKA 1LARA 2Y96A 1NO6A 1PXHA 1NNYA 2I6IA 3B7OA 3EZZA 2CNFA 4KI9A 3QCMA 4ZI4A 3EMUA 1M3GA 2IMGA 1RXDA 2OZ5A 3RGOA 2HCMA 1I9TA 1ECVA 1WAXA 2J17A 2FJMA 3I36A 1OESA 1LQFA 4B04A 3ZM1A 3S4EA 1ZCKA 3V0DA 2I75A 2HNQA 4DGPA 2I3RA 4JNBA 1YZ4A 2HY3A 4Z6BA 2I6PA 3ZMQA 4WU3A 5KA4A 3QCKA 5BZXA 1SUGA 2QBQA 2NLKA 2H04A 3CWEA 1PA9A 1OEOX 4NX8A 1ZC0A 4Y2EA 2PI7A 4H1OA 2CNEA 1KAKA 2I1YA 5KABA 2ESBA 3S3HA 2PSZA 2QDMA 4RI5A 1RPMA 5AWXA 3S4OA 2A3KA 1P15A 3QCFA 3D1HA 5IBSA 2GWOA 2GJTA 1PYNA 2BGEA 2BZLA 4ZN5A 1AAXA 1YTWA 1I9SA 3AWGA 1PH0A 5J8RA 2B49A 3BM8A 2QEPA 2CM8A 2G59A 1G1FA 2FJNA 3H2XA 2H4GA 3S3KA 4QAPA 2C46A 1FQ1A 1C85A 3V0JA 4JMKA 3RGQA 3BLTA 1YN9A 5K24A 1C87A 1VHRA 2I6JA 5K9WA 3I80A 1YWFA 1T48A 2F6VA 4RHGA 3MOWA 2G6ZA 3QCLA 3BRHA 1U25A 5KA3A 3SMEA 2I42A 1Q1MA 2B4UA 2R0BA 1OEVA 1EEOA 2RF6A 4KYQA 4R0TA 3QCGA 4HJQA 3NMEA 3LJ8A 1BZHA 2PQ5A 5GTJA 4QUNA 1J4XA 1OEUA 5I6VA 2OUDA 3ZM2A 1C88A 4GWFA 4QAHA 2CM2A 3N0AA 3ZM3A 3D1OA 2C7SA 1G4WR 1XXVA 2OOQA 4MBBA 2Y2FA 1I57A 2PT0A 4WTYA 2NTAA 1GWZA 1PA1A 1OETA 3F9AA 1OHCA 2HNPA 1Q6NA 2CMCA 1Q6MA 3QCJA 1YFOA 2I3UA 1A5YA 5LXQB 4JMJA 4KYRA 2F6FA 4DGXA 4OHDA 1LYVA 1PTUA 3EAXA 5M43A 5EHPA 1OEMX 2F71A 2HC1A 4ERCA 2QDPA 4IKCA 4QUMA 4WOHA 3F9BA 3QCEA 2I6MA 4NYHA 4GFVA 2HB1A 2I4GA 2H4VA 3MMJA 4S0GA 2F6WA 2GP0A 2Q05A 5K23A 2SHPA 2CFVA 4I8NA 3AWEA 3V0IA 4YAAA 2CM3A 5KAAA 2CMBA 2B07A 3PS5A 2HXPA 5HDEA 5BX1A 5KA8A 1G4US 1JF7A 2VEWA
chains in the Genus database with same CATH superfamily
2H03A 4PYHA 5MMZB 3O3LA 2FH7A 1V3AA 2HC2A 1C86A 1L8KA 1C83A 4BPCA 4RH9A 2PA5A 2UAGA 1YPTA 4QBWA 4QBEA 2NV5A 1ONZA 2WTZA 4GFUA 4QF5A 1P3DA 1Q6JA 4HV4A 2JFFA 4GE6A 1GFYA 2I6OA 3O4SA 1WCHA 3QCDA 4D3QA 1G1GA 2VEXA 3S3FA 3RO1A 1PTYA 1P31A 3F41A 1JLNA 3QKPA 2YDUA 3ZM0A 2AHSA 1X24A 2F00A 2VTEA 1MKPA 5KA0A 3ZMPA 2HVLA 4RI4A 2F6TA 4D3PA 3GXHA 2VEUA 4BUBA 4JBCA 1EENA 1G7FA 1C84A 4OHIA 5KA9A 2I4HA 5EHRA 3SR9A 2PBNA 2AZRA 2X5OA 2VOSA 3F99A 2BGDA 1NWEA 3QCCA 1W78A 4GE5A 3QCBA 2CJZA 2OC3A 2AM1A 2QBRA 4NWFA 3V0FA 1XRIA 4R0SA 1D5RA 3QCIA 1GQYA 1BZCA 4R30A 1U24A 2I5XA 1T4JA 2B4OA 2QCJA 4OHEA 5BUGA 2QDCA 2F70A 2B4PA 5K25A 2JJDA 3MOZA 2H02A 1XM2A 4ICZA 2P4DA 3V0EA 3O4UA 2BIJA 1EEHA 3M4UA 4TVVA 3QCZA 5KA7A 4OHHA 3EB1A 2P6XA 4ZRTA 5KADA 3S3EA 2E0TA 3BLUA 2JFGA 4H34A 5KACA 2CMAA 4GRZA 2Y1OA 2J16A 1QZ0A 1BZJA 1FPZA 2VTDA 1XXPA 2ZMMA 1Q6SA 3AWFA 4CVLA 5K22A 5A5EA 1OHEA 1G1HA 3U96A 4NNDA 5A5FA 1ONYA 2B3OA 3ZM5A 4RDDA 2VEVA 3LK7A 5KA2A 2QBSA 5IBMA 1NWLA 2XJAA 1YGUA 3EU0A 1PTTA 4YR8B 3QCHA 3D42A 4OHLA 2F46A 5KA1A 4GRYA 2I4EA 2Y67A 3D44A 2WGPA 1U26A 3PYZA 2J16B 1PTVA 1Q6PA 1FPRA 1W7KA 3QKQA 4RKKA 1L8GA 3D1QA 1WRMA 4AZ1A 3I7ZA 3V0GA 1R6HA 1XBOA 4RH5A 1JBWA 1YGRA 3V0HA 2VEYA 2CNGA 2CNHA 4HJPA 5BZZA 4Y14A 3O4TA 3ZV2A 4WU2A 2ZN7A 3GXGA 2MBCA 2QBPA 3RZ2A 3QCNA 2Q47A 1GG4A 2GCAA 5K9VA 1T49A 2A8BA 2H4KA 4D3RA 1G7GA 4GE2A 1NL9A 2BV5A 2QCTA 4BJOA 4HRFA 2F6YA 2F6ZA 1YTNA 3A5KA 3OMHA 2NT2A 1KAVA 2CM7A 1YTSA 2CNIA 3F81A 4PVGA 4C13A 2M3VA 2NT7A 2XPCA 3CM3A 1ZCLA 3O5XA 3D9CA 1NZ7A 3OLRA 4GS0A 1OHDA 1ZZWA 2DXPA 2NZ6A 3A5JA 4NWGA 3ZL8A 2B4SA 2Y66A 4J51A 1Q6TA 1QXKA 3HN7A 4CVMA 1LARA 2Y96A 1NO6A 1PXHA 1NNYA 2I6IA 3B7OA 3EZZA 2CNFA 1E8CA 4KI9A 3QCMA 4QDIA 4ZI4A 3EMUA 1M3GA 2IMGA 1RXDA 2OZ5A 3RGOA 2HCMA 1I9TA 1ECVA 1WAXA 2J17A 2FJMA 3I36A 1OESA 1LQFA 4B04A 3ZM1A 2AM2A 3S4EA 2Y68A 1ZCKA 3V0DA 2I75A 2HNQA 4DGPA 2I3RA 4JNBA 3ZM6A 1YZ4A 2HY3A 4Z6BA 2I6PA 3ZMQA 4WU3A 5KA4A 1JBVA 3QCKA 5BZXA 1SUGA 2QBQA 4ZIYA 2NLKA 2H04A 3CWEA 1PA9A 1OEOX 4NX8A 1ZC0A 4Y2EA 2PI7A 4H1OA 2CNEA 1KAKA 2I1YA 5KABA 2ESBA 3S3HA 2PSZA 2UUPA 2QDMA 4RI5A 1RPMA 4BUCA 5AWXA 1FGSA 2GC6A 3S4OA 2A3KA 1P15A 3QCFA 3D1HA 5IBSA 1J6UA 4CVKA 2GWOA 1GQQA 2GJTA 1PYNA 2BGEA 2BZLA 4ZN5A 1AAXA 1YTWA 1I9SA 3AWGA 1PH0A 5J8RA 2B49A 3BM8A 2QEPA 2CM8A 2G59A 1G1FA 2FJNA 3H2XA 2H4GA 3S3KA 4QAPA 2C46A 1FQ1A 1C85A 3V0JA 4JMKA 3RGQA 3BLTA 1YN9A 5K24A 1C87A 1VHRA 2I6JA 5K9WA 3I80A 1YWFA 1T48A 2F6VA 2GCBA 4RHGA 3MOWA 2G6ZA 3QCLA 3NRSA 3BRHA 1U25A 2WJPA 5KA3A 4UAGA 3SMEA 2I42A 1Q1MA 2B4UA 2R0BA 1OEVA 1EEOA 2RF6A 4KYQA 4R0TA 3QCGA 4HJQA 3NMEA 3LJ8A 1BZHA 2PQ5A 5GTJA 4QUNA 1J4XA 1OEUA 3N2AA 5I6VA 2VORA 2OUDA 3ZM2A 1C88A 4GWFA 4QAHA 2CM2A 3N0AA 3ZM3A 3D1OA 2C7SA 1G4WR 1XXVA 2OOQA 4MBBA 2Y2FA 1I57A 1UAGA 2PT0A 4WTYA 2NTAA 1GWZA 1PA1A 1OETA 3F9AA 1O5ZA 1OHCA 2HNPA 2UUOA 1Q6NA 2CMCA 1Q6MA 3QCJA 1YFOA 2I3UA 1A5YA 5LXQB 4JMJA 2JFHA 4KYRA 2F6FA 4DGXA 4OHDA 1LYVA 1PTUA 3EAXA 5M43A 5EHPA 1OEMX 3UAGA 2F71A 2HC1A 4ERCA 2QDPA 4IKCA 4QUMA 4WOHA 3F9BA 3QCEA 2I6MA 4NYHA 4GFVA 2HB1A 2I4GA 2H4VA 3MMJA 4S0GA 2GC5A 2F6WA 2GP0A 2Q05A 3MVNA 5K23A 2SHPA 2CFVA 1E0DA 4I8NA 3AWEA 3V0IA 4YAAA 2CM3A 5KAAA 2CMBA 2B07A 3PS5A 2HXPA 5HDEA 5BX1A 5KA8A 1G4US 1JF7A 4C12A 2VEWA
chains in the Genus database with same CATH topology
2H03A 4PYHA 5MMZB 3O3LA 2FH7A 1V3AA 2HC2A 1C86A 1L8KA 1C83A 4BPCA 4RH9A 2PA5A 1YPTA 4QBWA 4QBEA 2NV5A 1ONZA 4GFUA 1Q6JA 4GE6A 1GFYA 2I6OA 3O4SA 1WCHA 3QCDA 4D3QA 1G1GA 2VEXA 3S3FA 3RO1A 1PTYA 3F41A 1JLNA 3QKPA 2YDUA 3ZM0A 2AHSA 1X24A 5KA0A 1MKPA 3ZMPA 2HVLA 4RI4A 2F6TA 4D3PA 3GXHA 2VEUA 4JBCA 1EENA 1G7FA 1C84A 4OHIA 5KA9A 2I4HA 5EHRA 3SR9A 2PBNA 2AZRA 3F99A 2BGDA 1NWEA 3QCCA 4GE5A 3QCBA 2CJZA 2OC3A 2QBRA 4NWFA 3V0FA 1XRIA 4R0SA 1D5RA 3QCIA 1BZCA 4R30A 1U24A 2I5XA 1T4JA 2B4OA 2QCJA 4OHEA 5BUGA 2QDCA 2F70A 2B4PA 5K25A 2JJDA 3MOZA 2H02A 1XM2A 4ICZA 2P4DA 3V0EA 3O4UA 2BIJA 3M4UA 4TVVA 5KA7A 4OHHA 3EB1A 2P6XA 4ZRTA 5KADA 3S3EA 2E0TA 3BLUA 4H34A 5KACA 2CMAA 4GRZA 2J16A 1QZ0A 1BZJA 1FPZA 1XXPA 2ZMMA 1Q6SA 3AWFA 5K22A 1OHEA 1G1HA 3U96A 4NNDA 1ONYA 2B3OA 4RDDA 2VEVA 5KA2A 2QBSA 5IBMA 1NWLA 1YGUA 3EU0A 1PTTA 4YR8B 3QCHA 3D42A 4OHLA 2F46A 5KA1A 4GRYA 2I4EA 3D44A 2WGPA 1U26A 2J16B 1PTVA 1Q6PA 1FPRA 3QKQA 4RKKA 1L8GA 3D1QA 1WRMA 4AZ1A 3I7ZA 3V0GA 1R6HA 1XBOA 4RH5A 1YGRA 3V0HA 2VEYA 2CNGA 2CNHA 4HJPA 5BZZA 4Y14A 3O4TA 3ZV2A 4WU2A 2ZN7A 3GXGA 2MBCA 2QBPA 3RZ2A 3QCNA 2Q47A 5K9VA 1T49A 2A8BA 2H4KA 4D3RA 1G7GA 4GE2A 1NL9A 2BV5A 2QCTA 4BJOA 4HRFA 2F6YA 2F6ZA 1YTNA 3A5KA 3OMHA 2NT2A 1KAVA 2CM7A 1YTSA 2CNIA 3F81A 4PVGA 2M3VA 2NT7A 3CM3A 1ZCLA 3O5XA 3D9CA 1NZ7A 3OLRA 4GS0A 1OHDA 1ZZWA 2DXPA 2NZ6A 3A5JA 4NWGA 2B4SA 4J51A 1Q6TA 1QXKA 1LARA 2Y96A 1NO6A 1PXHA 1NNYA 2I6IA 3B7OA 3EZZA 2CNFA 4KI9A 3QCMA 4ZI4A 3EMUA 1M3GA 2IMGA 1RXDA 2OZ5A 3RGOA 2HCMA 1I9TA 1ECVA 1WAXA 2J17A 2FJMA 3I36A 1OESA 1LQFA 4B04A 3ZM1A 3S4EA 1ZCKA 3V0DA 2I75A 2HNQA 4DGPA 2I3RA 4JNBA 1YZ4A 2HY3A 4Z6BA 2I6PA 3ZMQA 4WU3A 5KA4A 3QCKA 5BZXA 1SUGA 2QBQA 2NLKA 2H04A 3CWEA 1PA9A 1OEOX 4NX8A 1ZC0A 4Y2EA 2PI7A 4H1OA 2CNEA 1KAKA 2I1YA 5KABA 2ESBA 3S3HA 2PSZA 2QDMA 4RI5A 1RPMA 5AWXA 3S4OA 2A3KA 1P15A 3QCFA 3D1HA 5IBSA 2GWOA 2GJTA 1PYNA 2BGEA 2BZLA 4ZN5A 1AAXA 1YTWA 1I9SA 3AWGA 1PH0A 5J8RA 2B49A 3BM8A 2QEPA 2CM8A 2G59A 1G1FA 2FJNA 3H2XA 2H4GA 3S3KA 4QAPA 2C46A 1FQ1A 1C85A 3V0JA 4JMKA 3RGQA 3BLTA 1YN9A 5K24A 1C87A 1VHRA 2I6JA 5K9WA 3I80A 1YWFA 1T48A 2F6VA 4RHGA 3MOWA 2G6ZA 3QCLA 3BRHA 1U25A 5KA3A 3SMEA 2I42A 1Q1MA 2B4UA 2R0BA 1OEVA 1EEOA 2RF6A 4KYQA 4R0TA 3QCGA 4HJQA 3NMEA 3LJ8A 1BZHA 2PQ5A 5GTJA 4QUNA 1J4XA 1OEUA 5I6VA 2OUDA 3ZM2A 1C88A 4GWFA 4QAHA 2CM2A 3N0AA 3ZM3A 3D1OA 2C7SA 1G4WR 1XXVA 2OOQA 4MBBA 2Y2FA 1I57A 2PT0A 4WTYA 2NTAA 1GWZA 1PA1A 1OETA 3F9AA 1OHCA 2HNPA 1Q6NA 2CMCA 1Q6MA 3QCJA 1YFOA 2I3UA 1A5YA 5LXQB 4JMJA 4KYRA 2F6FA 4DGXA 4OHDA 1LYVA 1PTUA 3EAXA 5M43A 5EHPA 1OEMX 2F71A 2HC1A 4ERCA 2QDPA 4IKCA 4QUMA 4WOHA 3F9BA 3QCEA 2I6MA 4NYHA 4GFVA 2HB1A 2I4GA 2H4VA 3MMJA 4S0GA 2F6WA 2GP0A 2Q05A 5K23A 2SHPA 2CFVA 4I8NA 3AWEA 3V0IA 4YAAA 2CM3A 5KAAA 2CMBA 2B07A 3PS5A 2HXPA 5HDEA 5BX1A 5KA8A 1G4US 1JF7A 2VEWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H03 A;  4PYH A;  5MMZ B;  3O3L A;  2FH7 A;  1V3A A;  2HC2 A;  1C86 A;  1L8K A;  1C83 A;  4BPC A;  4RH9 A;  2PA5 A;  1YPT A;  4QBW A;  4QBE A;  2NV5 A;  1ONZ A;  4GFU A;  1Q6J A;  4GE6 A;  1GFY A;  2I6O A;  3O4S A;  1WCH A;  3QCD A;  4D3Q A;  1G1G A;  2VEX A;  3S3F A;  3RO1 A;  1PTY A;  3F41 A;  1JLN A;  3QKP A;  2YDU A;  3ZM0 A;  2AHS A;  1X24 A;  5KA0 A;  1MKP A;  3ZMP A;  2HVL A;  4RI4 A;  2F6T A;  4D3P A;  3GXH A;  2VEU A;  4JBC A;  1EEN A;  1G7F A;  1C84 A;  4OHI A;  5KA9 A;  2I4H A;  5EHR A;  3SR9 A;  2PBN A;  2AZR A;  3F99 A;  2BGD A;  1NWE A;  3QCC A;  4GE5 A;  3QCB A;  2CJZ A;  2OC3 A;  2QBR A;  4NWF A;  3V0F A;  1XRI A;  4R0S A;  1D5R A;  3QCI A;  1BZC A;  4R30 A;  1U24 A;  2I5X A;  1T4J A;  2B4O A;  2QCJ A;  4OHE A;  5BUG A;  2QDC A;  2F70 A;  2B4P A;  5K25 A;  2JJD A;  3MOZ A;  2H02 A;  1XM2 A;  4ICZ A;  2P4D A;  3V0E A;  3O4U A;  2BIJ A;  3M4U A;  4TVV A;  5KA7 A;  4OHH A;  3EB1 A;  2P6X A;  4ZRT A;  5KAD A;  3S3E A;  2E0T A;  3BLU A;  4H34 A;  5KAC A;  2CMA A;  4GRZ A;  2J16 A;  1QZ0 A;  1BZJ A;  1FPZ A;  1XXP A;  2ZMM A;  1Q6S A;  3AWF A;  5K22 A;  1OHE A;  1G1H A;  3U96 A;  4NND A;  1ONY A;  2B3O A;  4RDD A;  2VEV A;  5KA2 A;  2QBS A;  5IBM A;  1NWL A;  1YGU A;  3EU0 A;  1PTT A;  4YR8 B;  3QCH A;  3D42 A;  4OHL A;  2F46 A;  5KA1 A;  4GRY A;  2I4E A;  3D44 A;  2WGP A;  1U26 A;  2J16 B;  1PTV A;  1Q6P A;  1FPR A;  3QKQ A;  4RKK A;  1L8G A;  3D1Q A;  1WRM A;  4AZ1 A;  3I7Z A;  3V0G A;  1R6H A;  1XBO A;  4RH5 A;  1YGR A;  3V0H A;  2VEY A;  2CNG A;  2CNH A;  4HJP A;  5BZZ A;  4Y14 A;  3O4T A;  3ZV2 A;  4WU2 A;  2ZN7 A;  3GXG A;  2MBC A;  2QBP A;  3RZ2 A;  3QCN A;  2Q47 A;  5K9V A;  1T49 A;  2A8B A;  2H4K A;  4D3R A;  1G7G A;  4GE2 A;  1NL9 A;  2BV5 A;  2QCT A;  4BJO A;  4HRF A;  2F6Y A;  2F6Z A;  1YTN A;  3A5K A;  3OMH A;  2NT2 A;  1KAV A;  2CM7 A;  1YTS A;  2CNI A;  3F81 A;  4PVG A;  2M3V A;  2NT7 A;  3CM3 A;  1ZCL A;  3O5X A;  3D9C A;  1NZ7 A;  3OLR A;  4GS0 A;  1OHD A;  1ZZW A;  2DXP A;  2NZ6 A;  3A5J A;  4NWG A;  2B4S A;  4J51 A;  1Q6T A;  1QXK A;  1LAR A;  2Y96 A;  1NO6 A;  1PXH A;  1NNY A;  2I6I A;  3B7O A;  3EZZ A;  2CNF A;  4KI9 A;  3QCM A;  4ZI4 A;  3EMU A;  1M3G A;  2IMG A;  1RXD A;  2OZ5 A;  3RGO A;  2HCM A;  1I9T A;  1ECV A;  1WAX A;  2J17 A;  2FJM A;  3I36 A;  1OES A;  1LQF A;  4B04 A;  3ZM1 A;  3S4E A;  1ZCK A;  3V0D A;  2I75 A;  2HNQ A;  4DGP A;  2I3R A;  4JNB A;  1YZ4 A;  2HY3 A;  4Z6B A;  2I6P A;  3ZMQ A;  4WU3 A;  5KA4 A;  3QCK A;  5BZX A;  1SUG A;  2QBQ A;  2NLK A;  2H04 A;  3CWE A;  1PA9 A;  1OEO X;  4NX8 A;  1ZC0 A;  4Y2E A;  2PI7 A;  4H1O A;  2CNE A;  1KAK A;  2I1Y A;  5KAB A;  2ESB A;  3S3H A;  2PSZ A;  2QDM A;  4RI5 A;  1RPM A;  5AWX A;  3S4O A;  2A3K A;  1P15 A;  3QCF A;  3D1H A;  5IBS A;  2GWO A;  2GJT A;  1PYN A;  2BGE A;  2BZL A;  4ZN5 A;  1AAX A;  1YTW A;  1I9S A;  3AWG A;  1PH0 A;  5J8R A;  2B49 A;  3BM8 A;  2QEP A;  2CM8 A;  2G59 A;  1G1F A;  2FJN A;  3H2X A;  2H4G A;  3S3K A;  4QAP A;  2C46 A;  1FQ1 A;  1C85 A;  3V0J A;  4JMK A;  3RGQ A;  3BLT A;  1YN9 A;  5K24 A;  1C87 A;  1VHR A;  2I6J A;  5K9W A;  3I80 A;  1YWF A;  1T48 A;  2F6V A;  4RHG A;  3MOW A;  2G6Z A;  3QCL A;  3BRH A;  1U25 A;  5KA3 A;  3SME A;  2I42 A;  1Q1M A;  2B4U A;  2R0B A;  1OEV A;  1EEO A;  2RF6 A;  4KYQ A;  4R0T A;  3QCG A;  4HJQ A;  3NME A;  3LJ8 A;  1BZH A;  2PQ5 A;  5GTJ A;  4QUN A;  1J4X A;  1OEU A;  5I6V A;  2OUD A;  3ZM2 A;  1C88 A;  4GWF A;  4QAH A;  2CM2 A;  3N0A A;  3ZM3 A;  3D1O A;  2C7S A;  1G4W R;  1XXV A;  2OOQ A;  4MBB A;  2Y2F A;  1I57 A;  2PT0 A;  4WTY A;  2NTA A;  1GWZ A;  1PA1 A;  1OET A;  3F9A A;  1OHC A;  2HNP A;  1Q6N A;  2CMC A;  1Q6M A;  3QCJ A;  1YFO A;  2I3U A;  1A5Y A;  5LXQ B;  4JMJ A;  4KYR A;  2F6F A;  4DGX A;  4OHD A;  1LYV A;  1PTU A;  3EAX A;  5M43 A;  5EHP A;  1OEM X;  2F71 A;  2HC1 A;  4ERC A;  2QDP A;  4IKC A;  4QUM A;  4WOH A;  3F9B A;  3QCE A;  2I6M A;  4NYH A;  4GFV A;  2HB1 A;  2I4G A;  2H4V A;  3MMJ A;  4S0G A;  2F6W A;  2GP0 A;  2Q05 A;  5K23 A;  2SHP A;  2CFV A;  4I8N A;  3AWE A;  3V0I A;  4YAA A;  2CM3 A;  5KAA A;  2CMB A;  2B07 A;  3PS5 A;  2HXP A;  5HDE A;  5BX1 A;  5KA8 A;  1G4U S;  1JF7 A;  2VEW A; 
#chains in the Genus database with same CATH topology
 2H03 A;  4PYH A;  5MMZ B;  3O3L A;  2FH7 A;  1V3A A;  2HC2 A;  1C86 A;  1L8K A;  1C83 A;  4BPC A;  4RH9 A;  2PA5 A;  2UAG A;  1YPT A;  4QBW A;  4QBE A;  2NV5 A;  1ONZ A;  2WTZ A;  4GFU A;  4QF5 A;  1P3D A;  1Q6J A;  4HV4 A;  2JFF A;  4GE6 A;  1GFY A;  2I6O A;  3O4S A;  1WCH A;  3QCD A;  4D3Q A;  1G1G A;  2VEX A;  3S3F A;  3RO1 A;  1PTY A;  1P31 A;  3F41 A;  1JLN A;  3QKP A;  2YDU A;  3ZM0 A;  2AHS A;  1X24 A;  2F00 A;  2VTE A;  1MKP A;  5KA0 A;  3ZMP A;  2HVL A;  4RI4 A;  2F6T A;  4D3P A;  3GXH A;  2VEU A;  4BUB A;  4JBC A;  1EEN A;  1G7F A;  1C84 A;  4OHI A;  5KA9 A;  2I4H A;  5EHR A;  3SR9 A;  2PBN A;  2AZR A;  2X5O A;  2VOS A;  3F99 A;  2BGD A;  1NWE A;  3QCC A;  1W78 A;  4GE5 A;  3QCB A;  2CJZ A;  2OC3 A;  2AM1 A;  2QBR A;  4NWF A;  3V0F A;  1XRI A;  4R0S A;  1D5R A;  3QCI A;  1GQY A;  1BZC A;  4R30 A;  1U24 A;  2I5X A;  1T4J A;  2B4O A;  2QCJ A;  4OHE A;  5BUG A;  2QDC A;  2F70 A;  2B4P A;  5K25 A;  2JJD A;  3MOZ A;  2H02 A;  1XM2 A;  4ICZ A;  2P4D A;  3V0E A;  3O4U A;  2BIJ A;  1EEH A;  3M4U A;  4TVV A;  3QCZ A;  5KA7 A;  4OHH A;  3EB1 A;  2P6X A;  4ZRT A;  5KAD A;  3S3E A;  2E0T A;  3BLU A;  2JFG A;  4H34 A;  5KAC A;  2CMA A;  4GRZ A;  2Y1O A;  2J16 A;  1QZ0 A;  1BZJ A;  1FPZ A;  2VTD A;  1XXP A;  2ZMM A;  1Q6S A;  3AWF A;  4CVL A;  5K22 A;  5A5E A;  1OHE A;  1G1H A;  3U96 A;  4NND A;  5A5F A;  1ONY A;  2B3O A;  3ZM5 A;  4RDD A;  2VEV A;  3LK7 A;  5KA2 A;  2QBS A;  5IBM A;  1NWL A;  2XJA A;  1YGU A;  3EU0 A;  1PTT A;  4YR8 B;  3QCH A;  3D42 A;  4OHL A;  2F46 A;  5KA1 A;  4GRY A;  2I4E A;  2Y67 A;  3D44 A;  2WGP A;  1U26 A;  3PYZ A;  2J16 B;  1PTV A;  1Q6P A;  1FPR A;  1W7K A;  3QKQ A;  4RKK A;  1L8G A;  3D1Q A;  1WRM A;  4AZ1 A;  3I7Z A;  3V0G A;  1R6H A;  1XBO A;  4RH5 A;  1JBW A;  1YGR A;  3V0H A;  2VEY A;  2CNG A;  2CNH A;  4HJP A;  5BZZ A;  4Y14 A;  3O4T A;  3ZV2 A;  4WU2 A;  2ZN7 A;  3GXG A;  2MBC A;  2QBP A;  3RZ2 A;  3QCN A;  2Q47 A;  1GG4 A;  2GCA A;  5K9V A;  1T49 A;  2A8B A;  2H4K A;  4D3R A;  1G7G A;  4GE2 A;  1NL9 A;  2BV5 A;  2QCT A;  4BJO A;  4HRF A;  2F6Y A;  2F6Z A;  1YTN A;  3A5K A;  3OMH A;  2NT2 A;  1KAV A;  2CM7 A;  1YTS A;  2CNI A;  3F81 A;  4PVG A;  4C13 A;  2M3V A;  2NT7 A;  2XPC A;  3CM3 A;  1ZCL A;  3O5X A;  3D9C A;  1NZ7 A;  3OLR A;  4GS0 A;  1OHD A;  1ZZW A;  2DXP A;  2NZ6 A;  3A5J A;  4NWG A;  3ZL8 A;  2B4S A;  2Y66 A;  4J51 A;  1Q6T A;  1QXK A;  3HN7 A;  4CVM A;  1LAR A;  2Y96 A;  1NO6 A;  1PXH A;  1NNY A;  2I6I A;  3B7O A;  3EZZ A;  2CNF A;  1E8C A;  4KI9 A;  3QCM A;  4QDI A;  4ZI4 A;  3EMU A;  1M3G A;  2IMG A;  1RXD A;  2OZ5 A;  3RGO A;  2HCM A;  1I9T A;  1ECV A;  1WAX A;  2J17 A;  2FJM A;  3I36 A;  1OES A;  1LQF A;  4B04 A;  3ZM1 A;  2AM2 A;  3S4E A;  2Y68 A;  1ZCK A;  3V0D A;  2I75 A;  2HNQ A;  4DGP A;  2I3R A;  4JNB A;  3ZM6 A;  1YZ4 A;  2HY3 A;  4Z6B A;  2I6P A;  3ZMQ A;  4WU3 A;  5KA4 A;  1JBV A;  3QCK A;  5BZX A;  1SUG A;  2QBQ A;  4ZIY A;  2NLK A;  2H04 A;  3CWE A;  1PA9 A;  1OEO X;  4NX8 A;  1ZC0 A;  4Y2E A;  2PI7 A;  4H1O A;  2CNE A;  1KAK A;  2I1Y A;  5KAB A;  2ESB A;  3S3H A;  2PSZ A;  2UUP A;  2QDM A;  4RI5 A;  1RPM A;  4BUC A;  5AWX A;  1FGS A;  2GC6 A;  3S4O A;  2A3K A;  1P15 A;  3QCF A;  3D1H A;  5IBS A;  1J6U A;  4CVK A;  2GWO A;  1GQQ A;  2GJT A;  1PYN A;  2BGE A;  2BZL A;  4ZN5 A;  1AAX A;  1YTW A;  1I9S A;  3AWG A;  1PH0 A;  5J8R A;  2B49 A;  3BM8 A;  2QEP A;  2CM8 A;  2G59 A;  1G1F A;  2FJN A;  3H2X A;  2H4G A;  3S3K A;  4QAP A;  2C46 A;  1FQ1 A;  1C85 A;  3V0J A;  4JMK A;  3RGQ A;  3BLT A;  1YN9 A;  5K24 A;  1C87 A;  1VHR A;  2I6J A;  5K9W A;  3I80 A;  1YWF A;  1T48 A;  2F6V A;  2GCB A;  4RHG A;  3MOW A;  2G6Z A;  3QCL A;  3NRS A;  3BRH A;  1U25 A;  2WJP A;  5KA3 A;  4UAG A;  3SME A;  2I42 A;  1Q1M A;  2B4U A;  2R0B A;  1OEV A;  1EEO A;  2RF6 A;  4KYQ A;  4R0T A;  3QCG A;  4HJQ A;  3NME A;  3LJ8 A;  1BZH A;  2PQ5 A;  5GTJ A;  4QUN A;  1J4X A;  1OEU A;  3N2A A;  5I6V A;  2VOR A;  2OUD A;  3ZM2 A;  1C88 A;  4GWF A;  4QAH A;  2CM2 A;  3N0A A;  3ZM3 A;  3D1O A;  2C7S A;  1G4W R;  1XXV A;  2OOQ A;  4MBB A;  2Y2F A;  1I57 A;  1UAG A;  2PT0 A;  4WTY A;  2NTA A;  1GWZ A;  1PA1 A;  1OET A;  3F9A A;  1O5Z A;  1OHC A;  2HNP A;  2UUO A;  1Q6N A;  2CMC A;  1Q6M A;  3QCJ A;  1YFO A;  2I3U A;  1A5Y A;  5LXQ B;  4JMJ A;  2JFH A;  4KYR A;  2F6F A;  4DGX A;  4OHD A;  1LYV A;  1PTU A;  3EAX A;  5M43 A;  5EHP A;  1OEM X;  3UAG A;  2F71 A;  2HC1 A;  4ERC A;  2QDP A;  4IKC A;  4QUM A;  4WOH A;  3F9B A;  3QCE A;  2I6M A;  4NYH A;  4GFV A;  2HB1 A;  2I4G A;  2H4V A;  3MMJ A;  4S0G A;  2GC5 A;  2F6W A;  2GP0 A;  2Q05 A;  3MVN A;  5K23 A;  2SHP A;  2CFV A;  1E0D A;  4I8N A;  3AWE A;  3V0I A;  4YAA A;  2CM3 A;  5KAA A;  2CMB A;  2B07 A;  3PS5 A;  2HXP A;  5HDE A;  5BX1 A;  5KA8 A;  1G4U S;  1JF7 A;  4C12 A;  2VEW A; 
#chains in the Genus database with same CATH homology
 2H03 A;  4PYH A;  5MMZ B;  3O3L A;  2FH7 A;  1V3A A;  2HC2 A;  1C86 A;  1L8K A;  1C83 A;  4BPC A;  4RH9 A;  2PA5 A;  1YPT A;  4QBW A;  4QBE A;  2NV5 A;  1ONZ A;  4GFU A;  1Q6J A;  4GE6 A;  1GFY A;  2I6O A;  3O4S A;  1WCH A;  3QCD A;  4D3Q A;  1G1G A;  2VEX A;  3S3F A;  3RO1 A;  1PTY A;  3F41 A;  1JLN A;  3QKP A;  2YDU A;  3ZM0 A;  2AHS A;  1X24 A;  5KA0 A;  1MKP A;  3ZMP A;  2HVL A;  4RI4 A;  2F6T A;  4D3P A;  3GXH A;  2VEU A;  4JBC A;  1EEN A;  1G7F A;  1C84 A;  4OHI A;  5KA9 A;  2I4H A;  5EHR A;  3SR9 A;  2PBN A;  2AZR A;  3F99 A;  2BGD A;  1NWE A;  3QCC A;  4GE5 A;  3QCB A;  2CJZ A;  2OC3 A;  2QBR A;  4NWF A;  3V0F A;  1XRI A;  4R0S A;  1D5R A;  3QCI A;  1BZC A;  4R30 A;  1U24 A;  2I5X A;  1T4J A;  2B4O A;  2QCJ A;  4OHE A;  5BUG A;  2QDC A;  2F70 A;  2B4P A;  5K25 A;  2JJD A;  3MOZ A;  2H02 A;  1XM2 A;  4ICZ A;  2P4D A;  3V0E A;  3O4U A;  2BIJ A;  3M4U A;  4TVV A;  5KA7 A;  4OHH A;  3EB1 A;  2P6X A;  4ZRT A;  5KAD A;  3S3E A;  2E0T A;  3BLU A;  4H34 A;  5KAC A;  2CMA A;  4GRZ A;  2J16 A;  1QZ0 A;  1BZJ A;  1FPZ A;  1XXP A;  2ZMM A;  1Q6S A;  3AWF A;  5K22 A;  1OHE A;  1G1H A;  3U96 A;  4NND A;  1ONY A;  2B3O A;  4RDD A;  2VEV A;  5KA2 A;  2QBS A;  5IBM A;  1NWL A;  1YGU A;  3EU0 A;  1PTT A;  4YR8 B;  3QCH A;  3D42 A;  4OHL A;  2F46 A;  5KA1 A;  4GRY A;  2I4E A;  3D44 A;  2WGP A;  1U26 A;  2J16 B;  1PTV A;  1Q6P A;  1FPR A;  3QKQ A;  4RKK A;  1L8G A;  3D1Q A;  1WRM A;  4AZ1 A;  3I7Z A;  3V0G A;  1R6H A;  1XBO A;  4RH5 A;  1YGR A;  3V0H A;  2VEY A;  2CNG A;  2CNH A;  4HJP A;  5BZZ A;  4Y14 A;  3O4T A;  3ZV2 A;  4WU2 A;  2ZN7 A;  3GXG A;  2MBC A;  2QBP A;  3RZ2 A;  3QCN A;  2Q47 A;  5K9V A;  1T49 A;  2A8B A;  2H4K A;  4D3R A;  1G7G A;  4GE2 A;  1NL9 A;  2BV5 A;  2QCT A;  4BJO A;  4HRF A;  2F6Y A;  2F6Z A;  1YTN A;  3A5K A;  3OMH A;  2NT2 A;  1KAV A;  2CM7 A;  1YTS A;  2CNI A;  3F81 A;  4PVG A;  2M3V A;  2NT7 A;  3CM3 A;  1ZCL A;  3O5X A;  3D9C A;  1NZ7 A;  3OLR A;  4GS0 A;  1OHD A;  1ZZW A;  2DXP A;  2NZ6 A;  3A5J A;  4NWG A;  2B4S A;  4J51 A;  1Q6T A;  1QXK A;  1LAR A;  2Y96 A;  1NO6 A;  1PXH A;  1NNY A;  2I6I A;  3B7O A;  3EZZ A;  2CNF A;  4KI9 A;  3QCM A;  4ZI4 A;  3EMU A;  1M3G A;  2IMG A;  1RXD A;  2OZ5 A;  3RGO A;  2HCM A;  1I9T A;  1ECV A;  1WAX A;  2J17 A;  2FJM A;  3I36 A;  1OES A;  1LQF A;  4B04 A;  3ZM1 A;  3S4E A;  1ZCK A;  3V0D A;  2I75 A;  2HNQ A;  4DGP A;  2I3R A;  4JNB A;  1YZ4 A;  2HY3 A;  4Z6B A;  2I6P A;  3ZMQ A;  4WU3 A;  5KA4 A;  3QCK A;  5BZX A;  1SUG A;  2QBQ A;  2NLK A;  2H04 A;  3CWE A;  1PA9 A;  1OEO X;  4NX8 A;  1ZC0 A;  4Y2E A;  2PI7 A;  4H1O A;  2CNE A;  1KAK A;  2I1Y A;  5KAB A;  2ESB A;  3S3H A;  2PSZ A;  2QDM A;  4RI5 A;  1RPM A;  5AWX A;  3S4O A;  2A3K A;  1P15 A;  3QCF A;  3D1H A;  5IBS A;  2GWO A;  2GJT A;  1PYN A;  2BGE A;  2BZL A;  4ZN5 A;  1AAX A;  1YTW A;  1I9S A;  3AWG A;  1PH0 A;  5J8R A;  2B49 A;  3BM8 A;  2QEP A;  2CM8 A;  2G59 A;  1G1F A;  2FJN A;  3H2X A;  2H4G A;  3S3K A;  4QAP A;  2C46 A;  1FQ1 A;  1C85 A;  3V0J A;  4JMK A;  3RGQ A;  3BLT A;  1YN9 A;  5K24 A;  1C87 A;  1VHR A;  2I6J A;  5K9W A;  3I80 A;  1YWF A;  1T48 A;  2F6V A;  4RHG A;  3MOW A;  2G6Z A;  3QCL A;  3BRH A;  1U25 A;  5KA3 A;  3SME A;  2I42 A;  1Q1M A;  2B4U A;  2R0B A;  1OEV A;  1EEO A;  2RF6 A;  4KYQ A;  4R0T A;  3QCG A;  4HJQ A;  3NME A;  3LJ8 A;  1BZH A;  2PQ5 A;  5GTJ A;  4QUN A;  1J4X A;  1OEU A;  5I6V A;  2OUD A;  3ZM2 A;  1C88 A;  4GWF A;  4QAH A;  2CM2 A;  3N0A A;  3ZM3 A;  3D1O A;  2C7S A;  1G4W R;  1XXV A;  2OOQ A;  4MBB A;  2Y2F A;  1I57 A;  2PT0 A;  4WTY A;  2NTA A;  1GWZ A;  1PA1 A;  1OET A;  3F9A A;  1OHC A;  2HNP A;  1Q6N A;  2CMC A;  1Q6M A;  3QCJ A;  1YFO A;  2I3U A;  1A5Y A;  5LXQ B;  4JMJ A;  4KYR A;  2F6F A;  4DGX A;  4OHD A;  1LYV A;  1PTU A;  3EAX A;  5M43 A;  5EHP A;  1OEM X;  2F71 A;  2HC1 A;  4ERC A;  2QDP A;  4IKC A;  4QUM A;  4WOH A;  3F9B A;  3QCE A;  2I6M A;  4NYH A;  4GFV A;  2HB1 A;  2I4G A;  2H4V A;  3MMJ A;  4S0G A;  2F6W A;  2GP0 A;  2Q05 A;  5K23 A;  2SHP A;  2CFV A;  4I8N A;  3AWE A;  3V0I A;  4YAA A;  2CM3 A;  5KAA A;  2CMB A;  2B07 A;  3PS5 A;  2HXP A;  5HDE A;  5BX1 A;  5KA8 A;  1G4U S;  1JF7 A;  2VEW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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