5AWXA

Crystal structure of human ptprz d1 domain
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
293
structure length
283
Chain Sequence
GPAIPIKHFPKHVADLHASSGFTEEFEEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKLAQLAEKDGKLTDYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEKGRRKCDQYWPADGSEEYGNFLVTQKSVQVLAYYTVRNFTLRNTKIGRVVTQYHYTQWPDMGVPEYSLPVLTFVRKAAYAKRHAVGPVVVHCSAGVGRTGTYIVLDSMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma
pubmed doi rcsb
molecule keywords Receptor-type tyrosine-protein phosphatase zeta
molecule tags Hydrolase
source organism Homo sapiens
total genus 99
structure length 283
sequence length 293
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2015-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 5awxA00
2BZLA 3ZMQA 2VEVA 3V0DA 1PTTA 1OEMX 1G4US 4WU3A 1JF7A 2OC3A 3RZ2A 2I5XA 2E0TA 3F81A 3EB1A 3V0JA 2A3KA 3QCNA 4JMKA 2PA5A 3O4SA 1LQFA 2CMBA 2Y96A 1NWLA 3H2XA 3F41A 4ZRTA 3QCHA 4R30A 3QCIA 1GWZA 4OHDA 1ZCKA 2PT0A 2H4KA 4QUMA 1YTSA 4OHIA 1FPRA 4TVVA 1J4XA 2GP0A 1M3GA 1YN9A 1PTUA 1XXPA 2QDMA 1Q6MA 3F9AA 4GWFA 3F9BA 2I3RA 3I36A 1NL9A 2I4GA 4YR8B 4D3PA 2VEUA 1YWFA 3ZMPA 4QAPA 3EMUA 1YGRA 3NMEA 5K22A 1NWEA 1U25A 1KAVA 2FH7A 1ZCLA 4NWFA 5IBSA 5BX1A 3N0AA 2QCTA 2NT2A 1BZJA 5AWXA 3PS5A 2HCMA 4PVGA 1YTNA 1OHEA 2B3OA 1G7GA 5K24A 2FJNA 3AWEA 4H1OA 1BZCA 1PA1A 2F71A 4RI5A 3QCCA 1VHRA 3S3EA 1D5RA 4YAAA 4QUNA 5KA9A 4ZI4A 1AAXA 4HJQA 3D9CA 2A8BA 2PBNA 4WOHA 2CJZA 3AWGA 2PQ5A 3BRHA 5K9WA 2HNQA 1XM2A 2VEXA 4NNDA 2F46A 4S0GA 2G6ZA 2ZN7A 1NZ7A 1Q6JA 2JJDA 5BUGA 4GFVA 5KADA 3M4UA 3CWEA 5KACA 4GRYA 1OEUA 1XBOA 2QDCA 4PYHA 2C7SA 2FJMA 4QAHA 1MKPA 1ZZWA 2CFVA 2CMCA 2OOQA 1OESA 3D42A 2OUDA 3BLUA 2RF6A 3MOZA 2CNGA 2CNIA 2QDPA 2NZ6A 4OHLA 3BLTA 3OLRA 2QBRA 1A5YA 4Y2EA 2I4EA 2F6VA 3QCMA 4GFUA 3D1OA 4AZ1A 2R0BA 4RKKA 2NV5A 1ECVA 3O5XA 2CNEA 3QCGA 2H02A 1YGUA 4GS0A 3QCLA 4GE2A 4RI4A 2NLKA 4Z6BA 1XXVA 1RPMA 1R6HA 3SR9A 5K25A 1LYVA 3RGOA 2H4VA 4OHEA 1WAXA 4Y14A 1X24A 2M3VA 4OHHA 2C46A 1OHDA 4DGPA 2HB1A 3D1HA 2AZRA 2PSZA 1QXKA 2HXPA 1PYNA 4RHGA 1C86A 1RXDA 1YPTA 1PTVA 4ICZA 2HVLA 5KA3A 1V3AA 2B4OA 2B49A 2MBCA 4JMJA 4D3RA 2IMGA 1QZ0A 1YZ4A 3EAXA 2QBQA 2QCJA 1U24A 3U96A 2QBSA 2Y2FA 2VEYA 1GFYA 3V0GA 2ESBA 1U26A 4B04A 3ZM1A 2CMAA 1ZC0A 3D1QA 4R0TA 4NWGA 5MMZB 3O3LA 2GWOA 2BV5A 2H04A 1Q6NA 4GRZA 3S3HA 5EHRA 2I6PA 2HC2A 1P15A 4JBCA 1BZHA 3CM3A 4BJOA 1PA9A 1G1GA 5LXQB 3V0IA 2CNFA 2H4GA 1EEOA 2DXPA 1G1FA 2QEPA 3QKQA 2I6OA 3S3FA 3O4TA 2BGEA 5I6VA 2P6XA 1WCHA 2Q47A 5KA1A 2VEWA 3SMEA 3D44A 1PXHA 2F6TA 2BGDA 4RH5A 2G59A 4R0SA 1Q1MA 3B7OA 3V0EA 3QCDA 3QCBA 3AWFA 1PTYA 2PI7A 4BPCA 1C87A 3V0HA 3RO1A 1Q6PA 2I42A 1OHCA 1PH0A 2Q05A 1YTWA 4GE6A 1JLNA 3QKPA 1ONZA 2GJTA 5KA0A 2CM7A 3OMHA 3V0FA 2ZMMA 4WTYA 1SUGA 4ZN5A 1I9TA 4J51A 4KYQA 5KA8A 4RDDA 1Q6TA 1YFOA 3O4UA 2I1YA 2YDUA 2F6FA 3QCEA 2HY3A 4H34A 3S3KA 3ZM2A 4KI9A 4GE5A 1T49A 1G7FA 3GXHA 1OETA 4IKCA 5KA7A 1C84A 2I4HA 5K23A 2NTAA 4ERCA 3A5JA 5KAAA 5HDEA 2CM2A 3RGQA 2CM3A 3MMJA 2F6YA 1T4JA 3S4EA 2HNPA 4QBWA 2HC1A 3QCJA 2B4UA 1LARA 3MOWA 2I6MA 2J17A 2OZ5A 1NO6A 5KA4A 2F70A 2H03A 3EU0A 3BM8A 3F99A 2I75A 2SHPA 2F6WA 2CM8A 3I80A 1NNYA 3QCKA 2BIJA 2CNHA 1WRMA 2B4SA 3GXGA 3EZZA 4RH9A 3LJ8A 1T48A 1OEOX 1L8GA 1G4WR 2I6IA 1ONYA 4NYHA 2P4DA 5BZXA 1I9SA 4DGXA 1L8KA 4JNBA 2AHSA 4MBBA 5K9VA 5EHPA 4D3QA 2B4PA 3I7ZA 4HJPA 5KABA 4QBEA 1C83A 2J16A 1I57A 1FPZA 3QCFA 3ZM0A 2J16B 1KAKA 5BZZA 5KA2A 3ZM3A 2WGPA 2B07A 1C85A 3A5KA 4WU2A 1C88A 1FQ1A 4HRFA 4NX8A 1Q6SA 1EENA 5GTJA 2I3UA 4I8NA 1OEVA 5J8RA 5M43A 2NT7A 3ZV2A 2I6JA 1G1HA 1XRIA 2QBPA 4KYRA 3S4OA 5IBMA 2F6ZA
chains in the Genus database with same CATH superfamily
2BZLA 3ZMQA 2VEVA 3V0DA 1PTTA 1OEMX 1G4US 4WU3A 1JF7A 2OC3A 3RZ2A 2I5XA 4BUBA 2E0TA 3F81A 2JFHA 1JBWA 3EB1A 3V0JA 2A3KA 1J6UA 3QCNA 4JMKA 2PA5A 3ZM5A 3O4SA 1LQFA 2CMBA 2Y96A 1NWLA 3H2XA 3F41A 4ZRTA 3QCHA 4R30A 3QCIA 1GWZA 4OHDA 1ZCKA 2PT0A 2H4KA 1UAGA 4QUMA 2GCAA 1YTSA 4OHIA 1FPRA 4TVVA 1J4XA 2GP0A 1M3GA 1YN9A 1PTUA 1XXPA 2QDMA 1Q6MA 3F9AA 4GWFA 4C13A 3F9BA 2I3RA 2Y68A 3I36A 1NL9A 2I4GA 4YR8B 4D3PA 2VEUA 1YWFA 3ZMPA 4QAPA 3UAGA 3EMUA 1YGRA 3NMEA 5K22A 1NWEA 1U25A 1KAVA 2FH7A 1ZCLA 4NWFA 5IBSA 5BX1A 3N0AA 2QCTA 2NT2A 1BZJA 5AWXA 3PS5A 2HCMA 4PVGA 1YTNA 4HV4A 1OHEA 2B3OA 1G7GA 2VTDA 5K24A 2FJNA 3AWEA 4H1OA 1BZCA 1PA1A 2F71A 4RI5A 3QCCA 1VHRA 3S3EA 1D5RA 4YAAA 4QF5A 4QUNA 5KA9A 4ZI4A 1AAXA 4HJQA 3D9CA 2A8BA 2PBNA 2VOSA 4WOHA 2CJZA 3MVNA 3AWGA 2PQ5A 3BRHA 2Y1OA 2HNQA 5K9WA 1XM2A 2VEXA 4NNDA 2F46A 4S0GA 2G6ZA 2ZN7A 1NZ7A 1Q6JA 4C12A 2JJDA 5BUGA 2Y66A 4GFVA 5KADA 3M4UA 3CWEA 5KACA 4GRYA 1OEUA 1XBOA 2QDCA 4PYHA 2C7SA 2FJMA 4QAHA 1MKPA 1ZZWA 2CFVA 2CMCA 2OOQA 1OESA 3D42A 2OUDA 3BLUA 2RF6A 3MOZA 2CNGA 2CNIA 2QDPA 2NZ6A 4OHLA 3BLTA 3OLRA 2QBRA 4CVMA 1A5YA 4Y2EA 2I4EA 1P31A 2F6VA 1JBVA 3QCMA 3D1OA 4GFUA 4AZ1A 2R0BA 5A5FA 4RKKA 2NV5A 1ECVA 3O5XA 2CNEA 3QCGA 2H02A 1YGUA 4GS0A 3QCLA 4GE2A 4RI4A 2NLKA 4Z6BA 1XXVA 2Y67A 1RPMA 1R6HA 3SR9A 5K25A 3HN7A 1LYVA 3RGOA 2H4VA 4OHEA 1WAXA 4Y14A 1X24A 1GG4A 2M3VA 4OHHA 2C46A 1OHDA 4DGPA 2HB1A 3D1HA 2AZRA 2PSZA 4CVLA 1QXKA 2HXPA 2VORA 1PYNA 4RHGA 1C86A 4ZIYA 1RXDA 1YPTA 1PTVA 4ICZA 2HVLA 5KA3A 1V3AA 2B4OA 2B49A 2MBCA 4JMJA 3N2AA 1FGSA 1E0DA 4D3RA 2IMGA 1QZ0A 1YZ4A 3EAXA 2UAGA 2QBQA 2F00A 2GC6A 1U24A 2QCJA 3U96A 2QBSA 2Y2FA 2VEYA 1GFYA 3V0GA 2ESBA 1U26A 1EEHA 4B04A 3ZM1A 2CMAA 1ZC0A 3D1QA 4R0TA 4NWGA 5MMZB 3O3LA 2GWOA 2BV5A 2H04A 4BUCA 1Q6NA 4GRZA 3S3HA 5EHRA 2I6PA 2HC2A 1P15A 4JBCA 1BZHA 2WTZA 3CM3A 4BJOA 1PA9A 2XPCA 1G1GA 5LXQB 3V0IA 2CNFA 2H4GA 1GQQA 1EEOA 2DXPA 1G1FA 2QEPA 3QKQA 2I6OA 3S3FA 2AM2A 3O4TA 1W7KA 2BGEA 5I6VA 2P6XA 1WCHA 2Q47A 5KA1A 2VEWA 3SMEA 3D44A 3QCZA 1PXHA 2F6TA 2BGDA 4RH5A 2XJAA 2UUPA 2JFFA 2G59A 4R0SA 1Q1MA 3B7OA 3V0EA 3QCDA 3QCBA 3AWFA 1PTYA 2PI7A 4BPCA 1C87A 3V0HA 4UAGA 2GCBA 3RO1A 1Q6PA 2I42A 1OHCA 1PH0A 2Q05A 3LK7A 1YTWA 4GE6A 3ZM6A 1JLNA 3QKPA 1ONZA 2GJTA 5KA0A 2CM7A 3OMHA 3V0FA 2ZMMA 4WTYA 1SUGA 4ZN5A 1I9TA 4J51A 2UUOA 4KYQA 5KA8A 4RDDA 1Q6TA 1YFOA 3O4UA 2I1YA 2YDUA 2F6FA 3QCEA 2HY3A 4H34A 3S3KA 3ZM2A 4KI9A 4GE5A 1T49A 1G7FA 3GXHA 1OETA 4IKCA 5KA7A 1C84A 2I4HA 5K23A 2NTAA 4ERCA 3A5JA 5KAAA 5HDEA 2CM2A 2GC5A 3RGQA 2CM3A 3MMJA 4CVKA 2F6YA 2AM1A 1T4JA 3S4EA 2HNPA 4QBWA 2HC1A 3QCJA 2B4UA 1LARA 3MOWA 2I6MA 2J17A 2OZ5A 1NO6A 5KA4A 2F70A 2H03A 2VTEA 3EU0A 1W78A 3NRSA 2X5OA 3BM8A 3F99A 2I75A 2SHPA 2F6WA 2CM8A 3I80A 1NNYA 3QCKA 2BIJA 2CNHA 1WRMA 3PYZA 2B4SA 3GXGA 3EZZA 4RH9A 3LJ8A 1T48A 1OEOX 5A5EA 1O5ZA 1L8GA 1G4WR 2I6IA 1ONYA 4NYHA 2P4DA 5BZXA 1I9SA 4DGXA 1L8KA 4JNBA 2AHSA 4MBBA 5K9VA 5EHPA 4D3QA 2B4PA 3I7ZA 4HJPA 5KABA 4QBEA 1C83A 2J16A 1I57A 1FPZA 3QCFA 3ZM0A 2J16B 2JFGA 2WJPA 1KAKA 5BZZA 5KA2A 3ZM3A 2WGPA 2B07A 1C85A 3A5KA 4WU2A 1C88A 1FQ1A 4QDIA 3ZL8A 1P3DA 4HRFA 4NX8A 1GQYA 1Q6SA 1EENA 5GTJA 2I3UA 4I8NA 1OEVA 5J8RA 5M43A 2NT7A 1E8CA 3ZV2A 2I6JA 1G1HA 1XRIA 2QBPA 4KYRA 3S4OA 5IBMA 2F6ZA
chains in the Genus database with same CATH topology
2BZLA 3ZMQA 2VEVA 3V0DA 1PTTA 1OEMX 1G4US 4WU3A 1JF7A 2OC3A 3RZ2A 2I5XA 2E0TA 3F81A 3EB1A 3V0JA 2A3KA 3QCNA 4JMKA 2PA5A 3O4SA 1LQFA 2CMBA 2Y96A 1NWLA 3H2XA 3F41A 4ZRTA 3QCHA 4R30A 3QCIA 1GWZA 4OHDA 1ZCKA 2PT0A 2H4KA 4QUMA 1YTSA 4OHIA 1FPRA 4TVVA 1J4XA 2GP0A 1M3GA 1YN9A 1PTUA 1XXPA 2QDMA 1Q6MA 3F9AA 4GWFA 3F9BA 2I3RA 3I36A 1NL9A 2I4GA 4YR8B 4D3PA 2VEUA 1YWFA 3ZMPA 4QAPA 3EMUA 1YGRA 3NMEA 5K22A 1NWEA 1U25A 1KAVA 2FH7A 1ZCLA 4NWFA 5IBSA 5BX1A 3N0AA 2QCTA 2NT2A 1BZJA 5AWXA 3PS5A 2HCMA 4PVGA 1YTNA 1OHEA 2B3OA 1G7GA 5K24A 2FJNA 3AWEA 4H1OA 1BZCA 1PA1A 2F71A 4RI5A 3QCCA 1VHRA 3S3EA 1D5RA 4YAAA 4QUNA 5KA9A 4ZI4A 1AAXA 4HJQA 3D9CA 2A8BA 2PBNA 4WOHA 2CJZA 3AWGA 2PQ5A 3BRHA 5K9WA 2HNQA 1XM2A 2VEXA 4NNDA 2F46A 4S0GA 2G6ZA 2ZN7A 1NZ7A 1Q6JA 2JJDA 5BUGA 4GFVA 5KADA 3M4UA 3CWEA 5KACA 4GRYA 1OEUA 1XBOA 2QDCA 4PYHA 2C7SA 2FJMA 4QAHA 1MKPA 1ZZWA 2CFVA 2CMCA 2OOQA 1OESA 3D42A 2OUDA 3BLUA 2RF6A 3MOZA 2CNGA 2CNIA 2QDPA 2NZ6A 4OHLA 3BLTA 3OLRA 2QBRA 1A5YA 4Y2EA 2I4EA 2F6VA 3QCMA 4GFUA 3D1OA 4AZ1A 2R0BA 4RKKA 2NV5A 1ECVA 3O5XA 2CNEA 3QCGA 2H02A 1YGUA 4GS0A 3QCLA 4GE2A 4RI4A 2NLKA 4Z6BA 1XXVA 1RPMA 1R6HA 3SR9A 5K25A 1LYVA 3RGOA 2H4VA 4OHEA 1WAXA 4Y14A 1X24A 2M3VA 4OHHA 2C46A 1OHDA 4DGPA 2HB1A 3D1HA 2AZRA 2PSZA 1QXKA 2HXPA 1PYNA 4RHGA 1C86A 1RXDA 1YPTA 1PTVA 4ICZA 2HVLA 5KA3A 1V3AA 2B4OA 2B49A 2MBCA 4JMJA 4D3RA 2IMGA 1QZ0A 1YZ4A 3EAXA 2QBQA 2QCJA 1U24A 3U96A 2QBSA 2Y2FA 2VEYA 1GFYA 3V0GA 2ESBA 1U26A 4B04A 3ZM1A 2CMAA 1ZC0A 3D1QA 4R0TA 4NWGA 5MMZB 3O3LA 2GWOA 2BV5A 2H04A 1Q6NA 4GRZA 3S3HA 5EHRA 2I6PA 2HC2A 1P15A 4JBCA 1BZHA 3CM3A 4BJOA 1PA9A 1G1GA 5LXQB 3V0IA 2CNFA 2H4GA 1EEOA 2DXPA 1G1FA 2QEPA 3QKQA 2I6OA 3S3FA 3O4TA 2BGEA 5I6VA 2P6XA 1WCHA 2Q47A 5KA1A 2VEWA 3SMEA 3D44A 1PXHA 2F6TA 2BGDA 4RH5A 2G59A 4R0SA 1Q1MA 3B7OA 3V0EA 3QCDA 3QCBA 3AWFA 1PTYA 2PI7A 4BPCA 1C87A 3V0HA 3RO1A 1Q6PA 2I42A 1OHCA 1PH0A 2Q05A 1YTWA 4GE6A 1JLNA 3QKPA 1ONZA 2GJTA 5KA0A 2CM7A 3OMHA 3V0FA 2ZMMA 4WTYA 1SUGA 4ZN5A 1I9TA 4J51A 4KYQA 5KA8A 4RDDA 1Q6TA 1YFOA 3O4UA 2I1YA 2YDUA 2F6FA 3QCEA 2HY3A 4H34A 3S3KA 3ZM2A 4KI9A 4GE5A 1T49A 1G7FA 3GXHA 1OETA 4IKCA 5KA7A 1C84A 2I4HA 5K23A 2NTAA 4ERCA 3A5JA 5KAAA 5HDEA 2CM2A 3RGQA 2CM3A 3MMJA 2F6YA 1T4JA 3S4EA 2HNPA 4QBWA 2HC1A 3QCJA 2B4UA 1LARA 3MOWA 2I6MA 2J17A 2OZ5A 1NO6A 5KA4A 2F70A 2H03A 3EU0A 3BM8A 3F99A 2I75A 2SHPA 2F6WA 2CM8A 3I80A 1NNYA 3QCKA 2BIJA 2CNHA 1WRMA 2B4SA 3GXGA 3EZZA 4RH9A 3LJ8A 1T48A 1OEOX 1L8GA 1G4WR 2I6IA 1ONYA 4NYHA 2P4DA 5BZXA 1I9SA 4DGXA 1L8KA 4JNBA 2AHSA 4MBBA 5K9VA 5EHPA 4D3QA 2B4PA 3I7ZA 4HJPA 5KABA 4QBEA 1C83A 2J16A 1I57A 1FPZA 3QCFA 3ZM0A 2J16B 1KAKA 5BZZA 5KA2A 3ZM3A 2WGPA 2B07A 1C85A 3A5KA 4WU2A 1C88A 1FQ1A 4HRFA 4NX8A 1Q6SA 1EENA 5GTJA 2I3UA 4I8NA 1OEVA 5J8RA 5M43A 2NT7A 3ZV2A 2I6JA 1G1HA 1XRIA 2QBPA 4KYRA 3S4OA 5IBMA 2F6ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BZL A;  3ZMQ A;  2VEV A;  3V0D A;  1PTT A;  1OEM X;  1G4U S;  4WU3 A;  1JF7 A;  2OC3 A;  3RZ2 A;  2I5X A;  2E0T A;  3F81 A;  3EB1 A;  3V0J A;  2A3K A;  3QCN A;  4JMK A;  2PA5 A;  3O4S A;  1LQF A;  2CMB A;  2Y96 A;  1NWL A;  3H2X A;  3F41 A;  4ZRT A;  3QCH A;  4R30 A;  3QCI A;  1GWZ A;  4OHD A;  1ZCK A;  2PT0 A;  2H4K A;  4QUM A;  1YTS A;  4OHI A;  1FPR A;  4TVV A;  1J4X A;  2GP0 A;  1M3G A;  1YN9 A;  1PTU A;  1XXP A;  2QDM A;  1Q6M A;  3F9A A;  4GWF A;  3F9B A;  2I3R A;  3I36 A;  1NL9 A;  2I4G A;  4YR8 B;  4D3P A;  2VEU A;  1YWF A;  3ZMP A;  4QAP A;  3EMU A;  1YGR A;  3NME A;  5K22 A;  1NWE A;  1U25 A;  1KAV A;  2FH7 A;  1ZCL A;  4NWF A;  5IBS A;  5BX1 A;  3N0A A;  2QCT A;  2NT2 A;  1BZJ A;  5AWX A;  3PS5 A;  2HCM A;  4PVG A;  1YTN A;  1OHE A;  2B3O A;  1G7G A;  5K24 A;  2FJN A;  3AWE A;  4H1O A;  1BZC A;  1PA1 A;  2F71 A;  4RI5 A;  3QCC A;  1VHR A;  3S3E A;  1D5R A;  4YAA A;  4QUN A;  5KA9 A;  4ZI4 A;  1AAX A;  4HJQ A;  3D9C A;  2A8B A;  2PBN A;  4WOH A;  2CJZ A;  3AWG A;  2PQ5 A;  3BRH A;  5K9W A;  2HNQ A;  1XM2 A;  2VEX A;  4NND A;  2F46 A;  4S0G A;  2G6Z A;  2ZN7 A;  1NZ7 A;  1Q6J A;  2JJD A;  5BUG A;  4GFV A;  5KAD A;  3M4U A;  3CWE A;  5KAC A;  4GRY A;  1OEU A;  1XBO A;  2QDC A;  4PYH A;  2C7S A;  2FJM A;  4QAH A;  1MKP A;  1ZZW A;  2CFV A;  2CMC A;  2OOQ A;  1OES A;  3D42 A;  2OUD A;  3BLU A;  2RF6 A;  3MOZ A;  2CNG A;  2CNI A;  2QDP A;  2NZ6 A;  4OHL A;  3BLT A;  3OLR A;  2QBR A;  1A5Y A;  4Y2E A;  2I4E A;  2F6V A;  3QCM A;  4GFU A;  3D1O A;  4AZ1 A;  2R0B A;  4RKK A;  2NV5 A;  1ECV A;  3O5X A;  2CNE A;  3QCG A;  2H02 A;  1YGU A;  4GS0 A;  3QCL A;  4GE2 A;  4RI4 A;  2NLK A;  4Z6B A;  1XXV A;  1RPM A;  1R6H A;  3SR9 A;  5K25 A;  1LYV A;  3RGO A;  2H4V A;  4OHE A;  1WAX A;  4Y14 A;  1X24 A;  2M3V A;  4OHH A;  2C46 A;  1OHD A;  4DGP A;  2HB1 A;  3D1H A;  2AZR A;  2PSZ A;  1QXK A;  2HXP A;  1PYN A;  4RHG A;  1C86 A;  1RXD A;  1YPT A;  1PTV A;  4ICZ A;  2HVL A;  5KA3 A;  1V3A A;  2B4O A;  2B49 A;  2MBC A;  4JMJ A;  4D3R A;  2IMG A;  1QZ0 A;  1YZ4 A;  3EAX A;  2QBQ A;  2QCJ A;  1U24 A;  3U96 A;  2QBS A;  2Y2F A;  2VEY A;  1GFY A;  3V0G A;  2ESB A;  1U26 A;  4B04 A;  3ZM1 A;  2CMA A;  1ZC0 A;  3D1Q A;  4R0T A;  4NWG A;  5MMZ B;  3O3L A;  2GWO A;  2BV5 A;  2H04 A;  1Q6N A;  4GRZ A;  3S3H A;  5EHR A;  2I6P A;  2HC2 A;  1P15 A;  4JBC A;  1BZH A;  3CM3 A;  4BJO A;  1PA9 A;  1G1G A;  5LXQ B;  3V0I A;  2CNF A;  2H4G A;  1EEO A;  2DXP A;  1G1F A;  2QEP A;  3QKQ A;  2I6O A;  3S3F A;  3O4T A;  2BGE A;  5I6V A;  2P6X A;  1WCH A;  2Q47 A;  5KA1 A;  2VEW A;  3SME A;  3D44 A;  1PXH A;  2F6T A;  2BGD A;  4RH5 A;  2G59 A;  4R0S A;  1Q1M A;  3B7O A;  3V0E A;  3QCD A;  3QCB A;  3AWF A;  1PTY A;  2PI7 A;  4BPC A;  1C87 A;  3V0H A;  3RO1 A;  1Q6P A;  2I42 A;  1OHC A;  1PH0 A;  2Q05 A;  1YTW A;  4GE6 A;  1JLN A;  3QKP A;  1ONZ A;  2GJT A;  5KA0 A;  2CM7 A;  3OMH A;  3V0F A;  2ZMM A;  4WTY A;  1SUG A;  4ZN5 A;  1I9T A;  4J51 A;  4KYQ A;  5KA8 A;  4RDD A;  1Q6T A;  1YFO A;  3O4U A;  2I1Y A;  2YDU A;  2F6F A;  3QCE A;  2HY3 A;  4H34 A;  3S3K A;  3ZM2 A;  4KI9 A;  4GE5 A;  1T49 A;  1G7F A;  3GXH A;  1OET A;  4IKC A;  5KA7 A;  1C84 A;  2I4H A;  5K23 A;  2NTA A;  4ERC A;  3A5J A;  5KAA A;  5HDE A;  2CM2 A;  3RGQ A;  2CM3 A;  3MMJ A;  2F6Y A;  1T4J A;  3S4E A;  2HNP A;  4QBW A;  2HC1 A;  3QCJ A;  2B4U A;  1LAR A;  3MOW A;  2I6M A;  2J17 A;  2OZ5 A;  1NO6 A;  5KA4 A;  2F70 A;  2H03 A;  3EU0 A;  3BM8 A;  3F99 A;  2I75 A;  2SHP A;  2F6W A;  2CM8 A;  3I80 A;  1NNY A;  3QCK A;  2BIJ A;  2CNH A;  1WRM A;  2B4S A;  3GXG A;  3EZZ A;  4RH9 A;  3LJ8 A;  1T48 A;  1OEO X;  1L8G A;  1G4W R;  2I6I A;  1ONY A;  4NYH A;  2P4D A;  5BZX A;  1I9S A;  4DGX A;  1L8K A;  4JNB A;  2AHS A;  4MBB A;  5K9V A;  5EHP A;  4D3Q A;  2B4P A;  3I7Z A;  4HJP A;  5KAB A;  4QBE A;  1C83 A;  2J16 A;  1I57 A;  1FPZ A;  3QCF A;  3ZM0 A;  2J16 B;  1KAK A;  5BZZ A;  5KA2 A;  3ZM3 A;  2WGP A;  2B07 A;  1C85 A;  3A5K A;  4WU2 A;  1C88 A;  1FQ1 A;  4HRF A;  4NX8 A;  1Q6S A;  1EEN A;  5GTJ A;  2I3U A;  4I8N A;  1OEV A;  5J8R A;  5M43 A;  2NT7 A;  3ZV2 A;  2I6J A;  1G1H A;  1XRI A;  2QBP A;  4KYR A;  3S4O A;  5IBM A;  2F6Z A; 
#chains in the Genus database with same CATH topology
 2BZL A;  3ZMQ A;  2VEV A;  3V0D A;  1PTT A;  1OEM X;  1G4U S;  4WU3 A;  1JF7 A;  2OC3 A;  3RZ2 A;  2I5X A;  4BUB A;  2E0T A;  3F81 A;  2JFH A;  1JBW A;  3EB1 A;  3V0J A;  2A3K A;  1J6U A;  3QCN A;  4JMK A;  2PA5 A;  3ZM5 A;  3O4S A;  1LQF A;  2CMB A;  2Y96 A;  1NWL A;  3H2X A;  3F41 A;  4ZRT A;  3QCH A;  4R30 A;  3QCI A;  1GWZ A;  4OHD A;  1ZCK A;  2PT0 A;  2H4K A;  1UAG A;  4QUM A;  2GCA A;  1YTS A;  4OHI A;  1FPR A;  4TVV A;  1J4X A;  2GP0 A;  1M3G A;  1YN9 A;  1PTU A;  1XXP A;  2QDM A;  1Q6M A;  3F9A A;  4GWF A;  4C13 A;  3F9B A;  2I3R A;  2Y68 A;  3I36 A;  1NL9 A;  2I4G A;  4YR8 B;  4D3P A;  2VEU A;  1YWF A;  3ZMP A;  4QAP A;  3UAG A;  3EMU A;  1YGR A;  3NME A;  5K22 A;  1NWE A;  1U25 A;  1KAV A;  2FH7 A;  1ZCL A;  4NWF A;  5IBS A;  5BX1 A;  3N0A A;  2QCT A;  2NT2 A;  1BZJ A;  5AWX A;  3PS5 A;  2HCM A;  4PVG A;  1YTN A;  4HV4 A;  1OHE A;  2B3O A;  1G7G A;  2VTD A;  5K24 A;  2FJN A;  3AWE A;  4H1O A;  1BZC A;  1PA1 A;  2F71 A;  4RI5 A;  3QCC A;  1VHR A;  3S3E A;  1D5R A;  4YAA A;  4QF5 A;  4QUN A;  5KA9 A;  4ZI4 A;  1AAX A;  4HJQ A;  3D9C A;  2A8B A;  2PBN A;  2VOS A;  4WOH A;  2CJZ A;  3MVN A;  3AWG A;  2PQ5 A;  3BRH A;  2Y1O A;  2HNQ A;  5K9W A;  1XM2 A;  2VEX A;  4NND A;  2F46 A;  4S0G A;  2G6Z A;  2ZN7 A;  1NZ7 A;  1Q6J A;  4C12 A;  2JJD A;  5BUG A;  2Y66 A;  4GFV A;  5KAD A;  3M4U A;  3CWE A;  5KAC A;  4GRY A;  1OEU A;  1XBO A;  2QDC A;  4PYH A;  2C7S A;  2FJM A;  4QAH A;  1MKP A;  1ZZW A;  2CFV A;  2CMC A;  2OOQ A;  1OES A;  3D42 A;  2OUD A;  3BLU A;  2RF6 A;  3MOZ A;  2CNG A;  2CNI A;  2QDP A;  2NZ6 A;  4OHL A;  3BLT A;  3OLR A;  2QBR A;  4CVM A;  1A5Y A;  4Y2E A;  2I4E A;  1P31 A;  2F6V A;  1JBV A;  3QCM A;  3D1O A;  4GFU A;  4AZ1 A;  2R0B A;  5A5F A;  4RKK A;  2NV5 A;  1ECV A;  3O5X A;  2CNE A;  3QCG A;  2H02 A;  1YGU A;  4GS0 A;  3QCL A;  4GE2 A;  4RI4 A;  2NLK A;  4Z6B A;  1XXV A;  2Y67 A;  1RPM A;  1R6H A;  3SR9 A;  5K25 A;  3HN7 A;  1LYV A;  3RGO A;  2H4V A;  4OHE A;  1WAX A;  4Y14 A;  1X24 A;  1GG4 A;  2M3V A;  4OHH A;  2C46 A;  1OHD A;  4DGP A;  2HB1 A;  3D1H A;  2AZR A;  2PSZ A;  4CVL A;  1QXK A;  2HXP A;  2VOR A;  1PYN A;  4RHG A;  1C86 A;  4ZIY A;  1RXD A;  1YPT A;  1PTV A;  4ICZ A;  2HVL A;  5KA3 A;  1V3A A;  2B4O A;  2B49 A;  2MBC A;  4JMJ A;  3N2A A;  1FGS A;  1E0D A;  4D3R A;  2IMG A;  1QZ0 A;  1YZ4 A;  3EAX A;  2UAG A;  2QBQ A;  2F00 A;  2GC6 A;  1U24 A;  2QCJ A;  3U96 A;  2QBS A;  2Y2F A;  2VEY A;  1GFY A;  3V0G A;  2ESB A;  1U26 A;  1EEH A;  4B04 A;  3ZM1 A;  2CMA A;  1ZC0 A;  3D1Q A;  4R0T A;  4NWG A;  5MMZ B;  3O3L A;  2GWO A;  2BV5 A;  2H04 A;  4BUC A;  1Q6N A;  4GRZ A;  3S3H A;  5EHR A;  2I6P A;  2HC2 A;  1P15 A;  4JBC A;  1BZH A;  2WTZ A;  3CM3 A;  4BJO A;  1PA9 A;  2XPC A;  1G1G A;  5LXQ B;  3V0I A;  2CNF A;  2H4G A;  1GQQ A;  1EEO A;  2DXP A;  1G1F A;  2QEP A;  3QKQ A;  2I6O A;  3S3F A;  2AM2 A;  3O4T A;  1W7K A;  2BGE A;  5I6V A;  2P6X A;  1WCH A;  2Q47 A;  5KA1 A;  2VEW A;  3SME A;  3D44 A;  3QCZ A;  1PXH A;  2F6T A;  2BGD A;  4RH5 A;  2XJA A;  2UUP A;  2JFF A;  2G59 A;  4R0S A;  1Q1M A;  3B7O A;  3V0E A;  3QCD A;  3QCB A;  3AWF A;  1PTY A;  2PI7 A;  4BPC A;  1C87 A;  3V0H A;  4UAG A;  2GCB A;  3RO1 A;  1Q6P A;  2I42 A;  1OHC A;  1PH0 A;  2Q05 A;  3LK7 A;  1YTW A;  4GE6 A;  3ZM6 A;  1JLN A;  3QKP A;  1ONZ A;  2GJT A;  5KA0 A;  2CM7 A;  3OMH A;  3V0F A;  2ZMM A;  4WTY A;  1SUG A;  4ZN5 A;  1I9T A;  4J51 A;  2UUO A;  4KYQ A;  5KA8 A;  4RDD A;  1Q6T A;  1YFO A;  3O4U A;  2I1Y A;  2YDU A;  2F6F A;  3QCE A;  2HY3 A;  4H34 A;  3S3K A;  3ZM2 A;  4KI9 A;  4GE5 A;  1T49 A;  1G7F A;  3GXH A;  1OET A;  4IKC A;  5KA7 A;  1C84 A;  2I4H A;  5K23 A;  2NTA A;  4ERC A;  3A5J A;  5KAA A;  5HDE A;  2CM2 A;  2GC5 A;  3RGQ A;  2CM3 A;  3MMJ A;  4CVK A;  2F6Y A;  2AM1 A;  1T4J A;  3S4E A;  2HNP A;  4QBW A;  2HC1 A;  3QCJ A;  2B4U A;  1LAR A;  3MOW A;  2I6M A;  2J17 A;  2OZ5 A;  1NO6 A;  5KA4 A;  2F70 A;  2H03 A;  2VTE A;  3EU0 A;  1W78 A;  3NRS A;  2X5O A;  3BM8 A;  3F99 A;  2I75 A;  2SHP A;  2F6W A;  2CM8 A;  3I80 A;  1NNY A;  3QCK A;  2BIJ A;  2CNH A;  1WRM A;  3PYZ A;  2B4S A;  3GXG A;  3EZZ A;  4RH9 A;  3LJ8 A;  1T48 A;  1OEO X;  5A5E A;  1O5Z A;  1L8G A;  1G4W R;  2I6I A;  1ONY A;  4NYH A;  2P4D A;  5BZX A;  1I9S A;  4DGX A;  1L8K A;  4JNB A;  2AHS A;  4MBB A;  5K9V A;  5EHP A;  4D3Q A;  2B4P A;  3I7Z A;  4HJP A;  5KAB A;  4QBE A;  1C83 A;  2J16 A;  1I57 A;  1FPZ A;  3QCF A;  3ZM0 A;  2J16 B;  2JFG A;  2WJP A;  1KAK A;  5BZZ A;  5KA2 A;  3ZM3 A;  2WGP A;  2B07 A;  1C85 A;  3A5K A;  4WU2 A;  1C88 A;  1FQ1 A;  4QDI A;  3ZL8 A;  1P3D A;  4HRF A;  4NX8 A;  1GQY A;  1Q6S A;  1EEN A;  5GTJ A;  2I3U A;  4I8N A;  1OEV A;  5J8R A;  5M43 A;  2NT7 A;  1E8C A;  3ZV2 A;  2I6J A;  1G1H A;  1XRI A;  2QBP A;  4KYR A;  3S4O A;  5IBM A;  2F6Z A; 
#chains in the Genus database with same CATH homology
 2BZL A;  3ZMQ A;  2VEV A;  3V0D A;  1PTT A;  1OEM X;  1G4U S;  4WU3 A;  1JF7 A;  2OC3 A;  3RZ2 A;  2I5X A;  2E0T A;  3F81 A;  3EB1 A;  3V0J A;  2A3K A;  3QCN A;  4JMK A;  2PA5 A;  3O4S A;  1LQF A;  2CMB A;  2Y96 A;  1NWL A;  3H2X A;  3F41 A;  4ZRT A;  3QCH A;  4R30 A;  3QCI A;  1GWZ A;  4OHD A;  1ZCK A;  2PT0 A;  2H4K A;  4QUM A;  1YTS A;  4OHI A;  1FPR A;  4TVV A;  1J4X A;  2GP0 A;  1M3G A;  1YN9 A;  1PTU A;  1XXP A;  2QDM A;  1Q6M A;  3F9A A;  4GWF A;  3F9B A;  2I3R A;  3I36 A;  1NL9 A;  2I4G A;  4YR8 B;  4D3P A;  2VEU A;  1YWF A;  3ZMP A;  4QAP A;  3EMU A;  1YGR A;  3NME A;  5K22 A;  1NWE A;  1U25 A;  1KAV A;  2FH7 A;  1ZCL A;  4NWF A;  5IBS A;  5BX1 A;  3N0A A;  2QCT A;  2NT2 A;  1BZJ A;  5AWX A;  3PS5 A;  2HCM A;  4PVG A;  1YTN A;  1OHE A;  2B3O A;  1G7G A;  5K24 A;  2FJN A;  3AWE A;  4H1O A;  1BZC A;  1PA1 A;  2F71 A;  4RI5 A;  3QCC A;  1VHR A;  3S3E A;  1D5R A;  4YAA A;  4QUN A;  5KA9 A;  4ZI4 A;  1AAX A;  4HJQ A;  3D9C A;  2A8B A;  2PBN A;  4WOH A;  2CJZ A;  3AWG A;  2PQ5 A;  3BRH A;  5K9W A;  2HNQ A;  1XM2 A;  2VEX A;  4NND A;  2F46 A;  4S0G A;  2G6Z A;  2ZN7 A;  1NZ7 A;  1Q6J A;  2JJD A;  5BUG A;  4GFV A;  5KAD A;  3M4U A;  3CWE A;  5KAC A;  4GRY A;  1OEU A;  1XBO A;  2QDC A;  4PYH A;  2C7S A;  2FJM A;  4QAH A;  1MKP A;  1ZZW A;  2CFV A;  2CMC A;  2OOQ A;  1OES A;  3D42 A;  2OUD A;  3BLU A;  2RF6 A;  3MOZ A;  2CNG A;  2CNI A;  2QDP A;  2NZ6 A;  4OHL A;  3BLT A;  3OLR A;  2QBR A;  1A5Y A;  4Y2E A;  2I4E A;  2F6V A;  3QCM A;  4GFU A;  3D1O A;  4AZ1 A;  2R0B A;  4RKK A;  2NV5 A;  1ECV A;  3O5X A;  2CNE A;  3QCG A;  2H02 A;  1YGU A;  4GS0 A;  3QCL A;  4GE2 A;  4RI4 A;  2NLK A;  4Z6B A;  1XXV A;  1RPM A;  1R6H A;  3SR9 A;  5K25 A;  1LYV A;  3RGO A;  2H4V A;  4OHE A;  1WAX A;  4Y14 A;  1X24 A;  2M3V A;  4OHH A;  2C46 A;  1OHD A;  4DGP A;  2HB1 A;  3D1H A;  2AZR A;  2PSZ A;  1QXK A;  2HXP A;  1PYN A;  4RHG A;  1C86 A;  1RXD A;  1YPT A;  1PTV A;  4ICZ A;  2HVL A;  5KA3 A;  1V3A A;  2B4O A;  2B49 A;  2MBC A;  4JMJ A;  4D3R A;  2IMG A;  1QZ0 A;  1YZ4 A;  3EAX A;  2QBQ A;  2QCJ A;  1U24 A;  3U96 A;  2QBS A;  2Y2F A;  2VEY A;  1GFY A;  3V0G A;  2ESB A;  1U26 A;  4B04 A;  3ZM1 A;  2CMA A;  1ZC0 A;  3D1Q A;  4R0T A;  4NWG A;  5MMZ B;  3O3L A;  2GWO A;  2BV5 A;  2H04 A;  1Q6N A;  4GRZ A;  3S3H A;  5EHR A;  2I6P A;  2HC2 A;  1P15 A;  4JBC A;  1BZH A;  3CM3 A;  4BJO A;  1PA9 A;  1G1G A;  5LXQ B;  3V0I A;  2CNF A;  2H4G A;  1EEO A;  2DXP A;  1G1F A;  2QEP A;  3QKQ A;  2I6O A;  3S3F A;  3O4T A;  2BGE A;  5I6V A;  2P6X A;  1WCH A;  2Q47 A;  5KA1 A;  2VEW A;  3SME A;  3D44 A;  1PXH A;  2F6T A;  2BGD A;  4RH5 A;  2G59 A;  4R0S A;  1Q1M A;  3B7O A;  3V0E A;  3QCD A;  3QCB A;  3AWF A;  1PTY A;  2PI7 A;  4BPC A;  1C87 A;  3V0H A;  3RO1 A;  1Q6P A;  2I42 A;  1OHC A;  1PH0 A;  2Q05 A;  1YTW A;  4GE6 A;  1JLN A;  3QKP A;  1ONZ A;  2GJT A;  5KA0 A;  2CM7 A;  3OMH A;  3V0F A;  2ZMM A;  4WTY A;  1SUG A;  4ZN5 A;  1I9T A;  4J51 A;  4KYQ A;  5KA8 A;  4RDD A;  1Q6T A;  1YFO A;  3O4U A;  2I1Y A;  2YDU A;  2F6F A;  3QCE A;  2HY3 A;  4H34 A;  3S3K A;  3ZM2 A;  4KI9 A;  4GE5 A;  1T49 A;  1G7F A;  3GXH A;  1OET A;  4IKC A;  5KA7 A;  1C84 A;  2I4H A;  5K23 A;  2NTA A;  4ERC A;  3A5J A;  5KAA A;  5HDE A;  2CM2 A;  3RGQ A;  2CM3 A;  3MMJ A;  2F6Y A;  1T4J A;  3S4E A;  2HNP A;  4QBW A;  2HC1 A;  3QCJ A;  2B4U A;  1LAR A;  3MOW A;  2I6M A;  2J17 A;  2OZ5 A;  1NO6 A;  5KA4 A;  2F70 A;  2H03 A;  3EU0 A;  3BM8 A;  3F99 A;  2I75 A;  2SHP A;  2F6W A;  2CM8 A;  3I80 A;  1NNY A;  3QCK A;  2BIJ A;  2CNH A;  1WRM A;  2B4S A;  3GXG A;  3EZZ A;  4RH9 A;  3LJ8 A;  1T48 A;  1OEO X;  1L8G A;  1G4W R;  2I6I A;  1ONY A;  4NYH A;  2P4D A;  5BZX A;  1I9S A;  4DGX A;  1L8K A;  4JNB A;  2AHS A;  4MBB A;  5K9V A;  5EHP A;  4D3Q A;  2B4P A;  3I7Z A;  4HJP A;  5KAB A;  4QBE A;  1C83 A;  2J16 A;  1I57 A;  1FPZ A;  3QCF A;  3ZM0 A;  2J16 B;  1KAK A;  5BZZ A;  5KA2 A;  3ZM3 A;  2WGP A;  2B07 A;  1C85 A;  3A5K A;  4WU2 A;  1C88 A;  1FQ1 A;  4HRF A;  4NX8 A;  1Q6S A;  1EEN A;  5GTJ A;  2I3U A;  4I8N A;  1OEV A;  5J8R A;  5M43 A;  2NT7 A;  3ZV2 A;  2I6J A;  1G1H A;  1XRI A;  2QBP A;  4KYR A;  3S4O A;  5IBM A;  2F6Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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