2I4GA

Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with a sulfamic acid (soaking experiment)
Total Genus 100
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
293
structure length
289
Chain Sequence
KTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Engineering the catalytic domain of human protein tyrosine phosphatase beta for structure-based drug discovery.
pubmed doi rcsb
molecule keywords Receptor-type tyrosine-protein phosphatase beta
molecule tags Hydrolase
source organism Homo sapiens
total genus 100
structure length 289
sequence length 293
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2i4gA00
1AAXA 1U26A 2PA5A 5AWXA 4R0SA 1BZJA 2HC2A 1ECVA 1YFOA 4JNBA 3RGOA 3V0EA 4YR8B 3EAXA 2BIJA 1ZCKA 2VEWA 2JJDA 3B7OA 3BLUA 2G6ZA 3EB1A 3O4TA 1RPMA 3S3FA 3OMHA 1G1FA 1Q1MA 1NO6A 1ZCLA 3RO1A 5BX1A 4DGXA 2QBSA 2VEVA 2VEYA 2QCJA 2I6JA 2F6FA 1NNYA 4BPCA 3MMJA 2Y96A 1OETA 2CJZA 3QCBA 4RDDA 4NX8A 4Y2EA 2HC1A 2QBQA 5KA9A 1EENA 2NV5A 1C86A 4R0TA 1G7GA 4NYHA 3F41A 4DGPA 3S3HA 4WU3A 2G59A 2AZRA 1Q6JA 2YDUA 3ZM0A 2B49A 2I42A 1OEVA 2I5XA 2B07A 3D9CA 2Q47A 2I6IA 1NL9A 4PYHA 2HNPA 4GE6A 3LJ8A 2QCTA 1YWFA 4JMJA 1R6HA 1YTWA 1Q6NA 2CNIA 3O4UA 3CWEA 2HXPA 4OHHA 1G4US 4ZRTA 2P4DA 2HCMA 3QCCA 3BRHA 1U25A 3BLTA 4GFUA 3V0IA 2GWOA 2QDMA 2VEUA 3SR9A 2BGEA 3D42A 2A8BA 1VHRA 3S4OA 4OHDA 1Q6SA 4Y14A 2CMBA 4QUMA 5BZZA 2CMCA 5M43A 1YN9A 2GJTA 1Q6TA 2B4PA 2FJMA 3M4UA 1LARA 1V3AA 2B4UA 4GRYA 3ZM1A 1RXDA 2H4KA 1M3GA 1GFYA 2PSZA 5KA2A 2QDCA 5I6VA 2NLKA 1OEUA 4H1OA 4HRFA 2IMGA 1PA9A 2QBPA 2F6ZA 3A5KA 3F9AA 5KAAA 1GWZA 5K25A 5KA4A 2J16B 5IBSA 2CNHA 2FJNA 4KI9A 2F6WA 4RH5A 3D1HA 1A5YA 4HJPA 1XXPA 1ONZA 3I36A 1OESA 2I3RA 3EU0A 5K9VA 1YPTA 4JBCA 2AHSA 3QCNA 4QAPA 2BZLA 5EHPA 2CMAA 3F9BA 3RZ2A 1L8KA 2I4EA 4H34A 1LYVA 2B3OA 3D1OA 5K23A 1YTNA 1PTVA 2PQ5A 1OHEA 3QCJA 4GE5A 2DXPA 4GS0A 2PI7A 2H4GA 4OHEA 1P15A 3V0GA 3I80A 3GXHA 1T49A 3QCKA 3PS5A 3U96A 4PVGA 2J16A 2H02A 5BUGA 2I4GA 4QBEA 5K22A 5KA7A 4BJOA 4RH9A 1ZZWA 2OUDA 1NWLA 4RHGA 4GE2A 2I1YA 3QCIA 3ZV2A 1C88A 3QCMA 2HNQA 3D44A 2NT7A 2BV5A 2I6MA 3BM8A 2MBCA 4MBBA 2F70A 3GXGA 3QKPA 3O4SA 1T48A 4QBWA 3I7ZA 1FQ1A 3AWEA 1U24A 1BZHA 3QCLA 1QXKA 5KABA 5KADA 1YGUA 4QUNA 2QEPA 4NWFA 2NT2A 1OEOX 2M3VA 5KA8A 2CFVA 2OOQA 2C7SA 2OC3A 1SUGA 1MKPA 5MMZB 2PT0A 4GFVA 2QBRA 4HJQA 3A5JA 1C83A 4QAHA 1G1HA 1L8GA 1LQFA 2Q05A 2I4HA 2QDPA 2NZ6A 1JF7A 1PTUA 4KYRA 1I57A 2GP0A 2F46A 3NMEA 5LXQB 3D1QA 2F6TA 4WOHA 4ZN5A 4RKKA 4D3PA 2OZ5A 4YAAA 2I75A 3S4EA 2R0BA 4ZI4A 3QCGA 4RI4A 1G1GA 3QCDA 1XBOA 5EHRA 1PTYA 2ZN7A 2RF6A 4WU2A 4OHIA 1X24A 4IKCA 5K24A 2CM7A 2Y2FA 1OHDA 3AWFA 3O3LA 4NWGA 4ERCA 5IBMA 2E0TA 5K9WA 3QCEA 2BGDA 4GWFA 2CM3A 2FH7A 4Z6BA 2I6PA 5HDEA 1C85A 3N0AA 3SMEA 2A3KA 1XXVA 1C84A 1YTSA 1C87A 2F6VA 1YZ4A 1Q6PA 1Q6MA 1FPZA 1J4XA 1KAVA 3AWGA 5KA0A 1I9TA 2J17A 3CM3A 2CNEA 3ZMQA 2F71A 4S0GA 3F99A 3QCHA 1ONYA 1I9SA 1G7FA 1EEOA 3V0FA 2CM2A 5KACA 4J51A 2I3UA 2HVLA 1NZ7A 4AZ1A 3H2XA 3EZZA 4R30A 1BZCA 4NNDA 2I6OA 3F81A 3QKQA 3V0JA 4B04A 3EMUA 2PBNA 5KA1A 4RI5A 4JMKA 1G4WR 2WGPA 4I8NA 2HY3A 4D3QA 3S3KA 2ESBA 3MOZA 1WAXA 2F6YA 1WCHA 2H04A 2ZMMA 5BZXA 2P6XA 1QZ0A 4TVVA 1NWEA 1OHCA 1ZC0A 2CNFA 3MOWA 4OHLA 1D5RA 1FPRA 2HB1A 1WRMA 2VEXA 3ZM2A 3QCFA 5J8RA 1PTTA 4WTYA 2CM8A 2H03A 1JLNA 3V0DA 1PA1A 1XM2A 4KYQA 4ICZA 1KAKA 3ZM3A 1YGRA 1PYNA 1OEMX 4GRZA 3S3EA 2H4VA 1PXHA 3RGQA 4D3RA 2B4OA 1XRIA 2SHPA 2B4SA 5KA3A 3ZMPA 3V0HA 3OLRA 1T4JA 5GTJA 1PH0A 3O5XA 2NTAA 2C46A 2CNGA
chains in the Genus database with same CATH superfamily
1AAXA 1U26A 2PA5A 5AWXA 4R0SA 1BZJA 2HC2A 1ECVA 1YFOA 1E0DA 2AM1A 4JNBA 3RGOA 3V0EA 4YR8B 3EAXA 2BIJA 1ZCKA 1W7KA 2VEWA 2JJDA 3B7OA 3BLUA 2G6ZA 3EB1A 3O4TA 4CVKA 1RPMA 3S3FA 3OMHA 1G1FA 1Q1MA 1NO6A 1ZCLA 3RO1A 5BX1A 4DGXA 2QBSA 2VEVA 2VEYA 2QCJA 2I6JA 2F6FA 1NNYA 4BPCA 5A5EA 2JFFA 3MMJA 2Y96A 2GCAA 1OETA 2CJZA 3QCBA 4RDDA 4NX8A 4Y2EA 2HC1A 2QBQA 5KA9A 1EENA 2NV5A 1C86A 4R0TA 1G7GA 2VOSA 2JFHA 4NYHA 3F41A 4DGPA 3S3HA 4WU3A 2G59A 2AZRA 1Q6JA 2YDUA 3ZM0A 2B49A 2I42A 1OEVA 3D9CA 2B07A 2I5XA 2Q47A 2I6IA 1NL9A 4PYHA 2HNPA 4GE6A 1J6UA 1P3DA 3LJ8A 2QCTA 4QF5A 1YWFA 4JMJA 1R6HA 1YTWA 1Q6NA 2CNIA 4C12A 3O4UA 3CWEA 2XPCA 2HXPA 4OHHA 1G4US 4ZRTA 2P4DA 2HCMA 2Y67A 3QCCA 3BRHA 1U25A 3BLTA 4GFUA 3V0IA 2GWOA 2QDMA 2GCBA 2VEUA 3SR9A 2BGEA 3D42A 2A8BA 1VHRA 3S4OA 4OHDA 1Q6SA 2X5OA 4Y14A 2CMBA 4QUMA 5BZZA 2Y68A 2CMCA 5M43A 4CVLA 1YN9A 2GJTA 1Q6TA 2B4PA 2FJMA 3M4UA 1LARA 1V3AA 2B4UA 4HV4A 4GRYA 3ZM1A 1RXDA 2H4KA 1M3GA 1GFYA 2PSZA 5KA2A 2QDCA 5I6VA 2NLKA 1OEUA 4H1OA 4HRFA 4BUBA 2IMGA 1PA9A 2QBPA 2F6ZA 2VTDA 3A5KA 3F9AA 5KAAA 3UAGA 3ZM6A 1GWZA 5K25A 5KA4A 2J16B 5IBSA 2CNHA 2FJNA 4KI9A 2F6WA 3NRSA 4RH5A 3D1HA 1A5YA 4HJPA 1XXPA 4CVMA 1ONZA 3I36A 1OESA 2I3RA 3N2AA 3EU0A 5K9VA 1YPTA 4JBCA 3MVNA 2AHSA 3QCNA 4QAPA 2BZLA 3LK7A 5EHPA 2CMAA 3F9BA 3RZ2A 1L8KA 2Y66A 2I4EA 4H34A 1LYVA 2B3OA 3D1OA 5K23A 1YTNA 1PTVA 2PQ5A 1OHEA 3QCJA 4GE5A 2DXPA 4GS0A 2PI7A 2H4GA 2VORA 4OHEA 1EEHA 1P15A 3V0GA 3I80A 1E8CA 3GXHA 1T49A 3QCKA 3PS5A 3U96A 2UUPA 3PYZA 4PVGA 2J16A 2H02A 5BUGA 2I4GA 4QBEA 5K22A 5KA7A 4BJOA 4RH9A 1ZZWA 3ZM5A 2OUDA 1NWLA 4RHGA 4GE2A 2I1YA 3QCIA 3ZV2A 1C88A 3QCMA 2HNQA 3D44A 2NT7A 2BV5A 2I6MA 3BM8A 1JBWA 2MBCA 4MBBA 2F70A 3GXGA 4BUCA 2GC6A 3QKPA 3O4SA 1T48A 4QBWA 3I7ZA 1FQ1A 3AWEA 1U24A 1GQYA 1BZHA 3QCLA 1QXKA 5KABA 5KADA 1YGUA 4QUNA 2QEPA 4NWFA 2NT2A 1OEOX 2M3VA 5KA8A 2CFVA 2OOQA 2C7SA 2OC3A 1SUGA 1MKPA 5MMZB 2PT0A 4GFVA 2QBRA 4HJQA 3A5JA 1C83A 4QAHA 1G1HA 1L8GA 1LQFA 2Q05A 2I4HA 2QDPA 2NZ6A 1JF7A 1PTUA 4KYRA 1I57A 3ZL8A 2GP0A 2F46A 3NMEA 5LXQB 3D1QA 2F6TA 4WOHA 4ZN5A 4RKKA 4D3PA 2OZ5A 4YAAA 2F00A 2I75A 3S4EA 2R0BA 2Y1OA 4ZI4A 3QCGA 4RI4A 1G1GA 3QCDA 1XBOA 5EHRA 1PTYA 2ZN7A 2RF6A 4WU2A 4OHIA 1X24A 4IKCA 5K24A 2CM7A 2Y2FA 1OHDA 3AWFA 3O3LA 4NWGA 4C13A 4ERCA 5IBMA 2E0TA 5K9WA 3QCEA 2BGDA 2GC5A 3QCZA 4GWFA 2CM3A 2FH7A 4Z6BA 2I6PA 5HDEA 1C85A 3N0AA 3SMEA 2A3KA 1XXVA 1C84A 1YTSA 1C87A 2F6VA 1YZ4A 1Q6PA 1Q6MA 1FPZA 2XJAA 1J4XA 1KAVA 3AWGA 5KA0A 1I9TA 2J17A 2UUOA 3CM3A 2CNEA 2VTEA 3ZMQA 2F71A 4S0GA 3F99A 3QCHA 1ONYA 1I9SA 1G7FA 2JFGA 1EEOA 3V0FA 2CM2A 5KACA 4J51A 1GG4A 2I3UA 2HVLA 1NZ7A 4AZ1A 3H2XA 3EZZA 4R30A 2WTZA 1BZCA 4NNDA 2I6OA 3F81A 3QKQA 3V0JA 4B04A 3EMUA 1UAGA 2PBNA 5KA1A 4RI5A 2AM2A 4JMKA 1FGSA 1G4WR 2WGPA 2UAGA 2WJPA 4I8NA 2HY3A 4D3QA 3S3KA 2ESBA 3MOZA 1WAXA 2F6YA 1WCHA 2H04A 2ZMMA 5BZXA 2P6XA 1QZ0A 4TVVA 1NWEA 1OHCA 1ZC0A 4UAGA 2CNFA 3MOWA 4ZIYA 4QDIA 4OHLA 1D5RA 1FPRA 2HB1A 1WRMA 2VEXA 1P31A 3ZM2A 3QCFA 5J8RA 1PTTA 1O5ZA 4WTYA 2CM8A 2H03A 5A5FA 1JLNA 3V0DA 1PA1A 3HN7A 1XM2A 4KYQA 4ICZA 1KAKA 3ZM3A 1YGRA 1PYNA 1OEMX 4GRZA 3S3EA 2H4VA 1PXHA 3RGQA 4D3RA 2B4OA 1XRIA 2SHPA 2B4SA 5KA3A 3ZMPA 3V0HA 3OLRA 1T4JA 5GTJA 1GQQA 1PH0A 1JBVA 1W78A 3O5XA 2NTAA 2C46A 2CNGA
chains in the Genus database with same CATH topology
1AAXA 1U26A 2PA5A 5AWXA 4R0SA 1BZJA 2HC2A 1ECVA 1YFOA 4JNBA 3RGOA 3V0EA 4YR8B 3EAXA 2BIJA 1ZCKA 2VEWA 2JJDA 3B7OA 3BLUA 2G6ZA 3EB1A 3O4TA 1RPMA 3S3FA 3OMHA 1G1FA 1Q1MA 1NO6A 1ZCLA 3RO1A 5BX1A 4DGXA 2QBSA 2VEVA 2VEYA 2QCJA 2I6JA 2F6FA 1NNYA 4BPCA 3MMJA 2Y96A 1OETA 2CJZA 3QCBA 4RDDA 4NX8A 4Y2EA 2HC1A 2QBQA 5KA9A 1EENA 2NV5A 1C86A 4R0TA 1G7GA 4NYHA 3F41A 4DGPA 3S3HA 4WU3A 2G59A 2AZRA 1Q6JA 2YDUA 3ZM0A 2B49A 2I42A 1OEVA 2I5XA 2B07A 3D9CA 2Q47A 2I6IA 1NL9A 4PYHA 2HNPA 4GE6A 3LJ8A 2QCTA 1YWFA 4JMJA 1R6HA 1YTWA 1Q6NA 2CNIA 3O4UA 3CWEA 2HXPA 4OHHA 1G4US 4ZRTA 2P4DA 2HCMA 3QCCA 3BRHA 1U25A 3BLTA 4GFUA 3V0IA 2GWOA 2QDMA 2VEUA 3SR9A 2BGEA 3D42A 2A8BA 1VHRA 3S4OA 4OHDA 1Q6SA 4Y14A 2CMBA 4QUMA 5BZZA 2CMCA 5M43A 1YN9A 2GJTA 1Q6TA 2B4PA 2FJMA 3M4UA 1LARA 1V3AA 2B4UA 4GRYA 3ZM1A 1RXDA 2H4KA 1M3GA 1GFYA 2PSZA 5KA2A 2QDCA 5I6VA 2NLKA 1OEUA 4H1OA 4HRFA 2IMGA 1PA9A 2QBPA 2F6ZA 3A5KA 3F9AA 5KAAA 1GWZA 5K25A 5KA4A 2J16B 5IBSA 2CNHA 2FJNA 4KI9A 2F6WA 4RH5A 3D1HA 1A5YA 4HJPA 1XXPA 1ONZA 3I36A 1OESA 2I3RA 3EU0A 5K9VA 1YPTA 4JBCA 2AHSA 3QCNA 4QAPA 2BZLA 5EHPA 2CMAA 3F9BA 3RZ2A 1L8KA 2I4EA 4H34A 1LYVA 2B3OA 3D1OA 5K23A 1YTNA 1PTVA 2PQ5A 1OHEA 3QCJA 4GE5A 2DXPA 4GS0A 2PI7A 2H4GA 4OHEA 1P15A 3V0GA 3I80A 3GXHA 1T49A 3QCKA 3PS5A 3U96A 4PVGA 2J16A 2H02A 5BUGA 2I4GA 4QBEA 5K22A 5KA7A 4BJOA 4RH9A 1ZZWA 2OUDA 1NWLA 4RHGA 4GE2A 2I1YA 3QCIA 3ZV2A 1C88A 3QCMA 2HNQA 3D44A 2NT7A 2BV5A 2I6MA 3BM8A 2MBCA 4MBBA 2F70A 3GXGA 3QKPA 3O4SA 1T48A 4QBWA 3I7ZA 1FQ1A 3AWEA 1U24A 1BZHA 3QCLA 1QXKA 5KABA 5KADA 1YGUA 4QUNA 2QEPA 4NWFA 2NT2A 1OEOX 2M3VA 5KA8A 2CFVA 2OOQA 2C7SA 2OC3A 1SUGA 1MKPA 5MMZB 2PT0A 4GFVA 2QBRA 4HJQA 3A5JA 1C83A 4QAHA 1G1HA 1L8GA 1LQFA 2Q05A 2I4HA 2QDPA 2NZ6A 1JF7A 1PTUA 4KYRA 1I57A 2GP0A 2F46A 3NMEA 5LXQB 3D1QA 2F6TA 4WOHA 4ZN5A 4RKKA 4D3PA 2OZ5A 4YAAA 2I75A 3S4EA 2R0BA 4ZI4A 3QCGA 4RI4A 1G1GA 3QCDA 1XBOA 5EHRA 1PTYA 2ZN7A 2RF6A 4WU2A 4OHIA 1X24A 4IKCA 5K24A 2CM7A 2Y2FA 1OHDA 3AWFA 3O3LA 4NWGA 4ERCA 5IBMA 2E0TA 5K9WA 3QCEA 2BGDA 4GWFA 2CM3A 2FH7A 4Z6BA 2I6PA 5HDEA 1C85A 3N0AA 3SMEA 2A3KA 1XXVA 1C84A 1YTSA 1C87A 2F6VA 1YZ4A 1Q6PA 1Q6MA 1FPZA 1J4XA 1KAVA 3AWGA 5KA0A 1I9TA 2J17A 3CM3A 2CNEA 3ZMQA 2F71A 4S0GA 3F99A 3QCHA 1ONYA 1I9SA 1G7FA 1EEOA 3V0FA 2CM2A 5KACA 4J51A 2I3UA 2HVLA 1NZ7A 4AZ1A 3H2XA 3EZZA 4R30A 1BZCA 4NNDA 2I6OA 3F81A 3QKQA 3V0JA 4B04A 3EMUA 2PBNA 5KA1A 4RI5A 4JMKA 1G4WR 2WGPA 4I8NA 2HY3A 4D3QA 3S3KA 2ESBA 3MOZA 1WAXA 2F6YA 1WCHA 2H04A 2ZMMA 5BZXA 2P6XA 1QZ0A 4TVVA 1NWEA 1OHCA 1ZC0A 2CNFA 3MOWA 4OHLA 1D5RA 1FPRA 2HB1A 1WRMA 2VEXA 3ZM2A 3QCFA 5J8RA 1PTTA 4WTYA 2CM8A 2H03A 1JLNA 3V0DA 1PA1A 1XM2A 4KYQA 4ICZA 1KAKA 3ZM3A 1YGRA 1PYNA 1OEMX 4GRZA 3S3EA 2H4VA 1PXHA 3RGQA 4D3RA 2B4OA 1XRIA 2SHPA 2B4SA 5KA3A 3ZMPA 3V0HA 3OLRA 1T4JA 5GTJA 1PH0A 3O5XA 2NTAA 2C46A 2CNGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AAX A;  1U26 A;  2PA5 A;  5AWX A;  4R0S A;  1BZJ A;  2HC2 A;  1ECV A;  1YFO A;  4JNB A;  3RGO A;  3V0E A;  4YR8 B;  3EAX A;  2BIJ A;  1ZCK A;  2VEW A;  2JJD A;  3B7O A;  3BLU A;  2G6Z A;  3EB1 A;  3O4T A;  1RPM A;  3S3F A;  3OMH A;  1G1F A;  1Q1M A;  1NO6 A;  1ZCL A;  3RO1 A;  5BX1 A;  4DGX A;  2QBS A;  2VEV A;  2VEY A;  2QCJ A;  2I6J A;  2F6F A;  1NNY A;  4BPC A;  3MMJ A;  2Y96 A;  1OET A;  2CJZ A;  3QCB A;  4RDD A;  4NX8 A;  4Y2E A;  2HC1 A;  2QBQ A;  5KA9 A;  1EEN A;  2NV5 A;  1C86 A;  4R0T A;  1G7G A;  4NYH A;  3F41 A;  4DGP A;  3S3H A;  4WU3 A;  2G59 A;  2AZR A;  1Q6J A;  2YDU A;  3ZM0 A;  2B49 A;  2I42 A;  1OEV A;  2I5X A;  2B07 A;  3D9C A;  2Q47 A;  2I6I A;  1NL9 A;  4PYH A;  2HNP A;  4GE6 A;  3LJ8 A;  2QCT A;  1YWF A;  4JMJ A;  1R6H A;  1YTW A;  1Q6N A;  2CNI A;  3O4U A;  3CWE A;  2HXP A;  4OHH A;  1G4U S;  4ZRT A;  2P4D A;  2HCM A;  3QCC A;  3BRH A;  1U25 A;  3BLT A;  4GFU A;  3V0I A;  2GWO A;  2QDM A;  2VEU A;  3SR9 A;  2BGE A;  3D42 A;  2A8B A;  1VHR A;  3S4O A;  4OHD A;  1Q6S A;  4Y14 A;  2CMB A;  4QUM A;  5BZZ A;  2CMC A;  5M43 A;  1YN9 A;  2GJT A;  1Q6T A;  2B4P A;  2FJM A;  3M4U A;  1LAR A;  1V3A A;  2B4U A;  4GRY A;  3ZM1 A;  1RXD A;  2H4K A;  1M3G A;  1GFY A;  2PSZ A;  5KA2 A;  2QDC A;  5I6V A;  2NLK A;  1OEU A;  4H1O A;  4HRF A;  2IMG A;  1PA9 A;  2QBP A;  2F6Z A;  3A5K A;  3F9A A;  5KAA A;  1GWZ A;  5K25 A;  5KA4 A;  2J16 B;  5IBS A;  2CNH A;  2FJN A;  4KI9 A;  2F6W A;  4RH5 A;  3D1H A;  1A5Y A;  4HJP A;  1XXP A;  1ONZ A;  3I36 A;  1OES A;  2I3R A;  3EU0 A;  5K9V A;  1YPT A;  4JBC A;  2AHS A;  3QCN A;  4QAP A;  2BZL A;  5EHP A;  2CMA A;  3F9B A;  3RZ2 A;  1L8K A;  2I4E A;  4H34 A;  1LYV A;  2B3O A;  3D1O A;  5K23 A;  1YTN A;  1PTV A;  2PQ5 A;  1OHE A;  3QCJ A;  4GE5 A;  2DXP A;  4GS0 A;  2PI7 A;  2H4G A;  4OHE A;  1P15 A;  3V0G A;  3I80 A;  3GXH A;  1T49 A;  3QCK A;  3PS5 A;  3U96 A;  4PVG A;  2J16 A;  2H02 A;  5BUG A;  2I4G A;  4QBE A;  5K22 A;  5KA7 A;  4BJO A;  4RH9 A;  1ZZW A;  2OUD A;  1NWL A;  4RHG A;  4GE2 A;  2I1Y A;  3QCI A;  3ZV2 A;  1C88 A;  3QCM A;  2HNQ A;  3D44 A;  2NT7 A;  2BV5 A;  2I6M A;  3BM8 A;  2MBC A;  4MBB A;  2F70 A;  3GXG A;  3QKP A;  3O4S A;  1T48 A;  4QBW A;  3I7Z A;  1FQ1 A;  3AWE A;  1U24 A;  1BZH A;  3QCL A;  1QXK A;  5KAB A;  5KAD A;  1YGU A;  4QUN A;  2QEP A;  4NWF A;  2NT2 A;  1OEO X;  2M3V A;  5KA8 A;  2CFV A;  2OOQ A;  2C7S A;  2OC3 A;  1SUG A;  1MKP A;  5MMZ B;  2PT0 A;  4GFV A;  2QBR A;  4HJQ A;  3A5J A;  1C83 A;  4QAH A;  1G1H A;  1L8G A;  1LQF A;  2Q05 A;  2I4H A;  2QDP A;  2NZ6 A;  1JF7 A;  1PTU A;  4KYR A;  1I57 A;  2GP0 A;  2F46 A;  3NME A;  5LXQ B;  3D1Q A;  2F6T A;  4WOH A;  4ZN5 A;  4RKK A;  4D3P A;  2OZ5 A;  4YAA A;  2I75 A;  3S4E A;  2R0B A;  4ZI4 A;  3QCG A;  4RI4 A;  1G1G A;  3QCD A;  1XBO A;  5EHR A;  1PTY A;  2ZN7 A;  2RF6 A;  4WU2 A;  4OHI A;  1X24 A;  4IKC A;  5K24 A;  2CM7 A;  2Y2F A;  1OHD A;  3AWF A;  3O3L A;  4NWG A;  4ERC A;  5IBM A;  2E0T A;  5K9W A;  3QCE A;  2BGD A;  4GWF A;  2CM3 A;  2FH7 A;  4Z6B A;  2I6P A;  5HDE A;  1C85 A;  3N0A A;  3SME A;  2A3K A;  1XXV A;  1C84 A;  1YTS A;  1C87 A;  2F6V A;  1YZ4 A;  1Q6P A;  1Q6M A;  1FPZ A;  1J4X A;  1KAV A;  3AWG A;  5KA0 A;  1I9T A;  2J17 A;  3CM3 A;  2CNE A;  3ZMQ A;  2F71 A;  4S0G A;  3F99 A;  3QCH A;  1ONY A;  1I9S A;  1G7F A;  1EEO A;  3V0F A;  2CM2 A;  5KAC A;  4J51 A;  2I3U A;  2HVL A;  1NZ7 A;  4AZ1 A;  3H2X A;  3EZZ A;  4R30 A;  1BZC A;  4NND A;  2I6O A;  3F81 A;  3QKQ A;  3V0J A;  4B04 A;  3EMU A;  2PBN A;  5KA1 A;  4RI5 A;  4JMK A;  1G4W R;  2WGP A;  4I8N A;  2HY3 A;  4D3Q A;  3S3K A;  2ESB A;  3MOZ A;  1WAX A;  2F6Y A;  1WCH A;  2H04 A;  2ZMM A;  5BZX A;  2P6X A;  1QZ0 A;  4TVV A;  1NWE A;  1OHC A;  1ZC0 A;  2CNF A;  3MOW A;  4OHL A;  1D5R A;  1FPR A;  2HB1 A;  1WRM A;  2VEX A;  3ZM2 A;  3QCF A;  5J8R A;  1PTT A;  4WTY A;  2CM8 A;  2H03 A;  1JLN A;  3V0D A;  1PA1 A;  1XM2 A;  4KYQ A;  4ICZ A;  1KAK A;  3ZM3 A;  1YGR A;  1PYN A;  1OEM X;  4GRZ A;  3S3E A;  2H4V A;  1PXH A;  3RGQ A;  4D3R A;  2B4O A;  1XRI A;  2SHP A;  2B4S A;  5KA3 A;  3ZMP A;  3V0H A;  3OLR A;  1T4J A;  5GTJ A;  1PH0 A;  3O5X A;  2NTA A;  2C46 A;  2CNG A; 
#chains in the Genus database with same CATH topology
 1AAX A;  1U26 A;  2PA5 A;  5AWX A;  4R0S A;  1BZJ A;  2HC2 A;  1ECV A;  1YFO A;  1E0D A;  2AM1 A;  4JNB A;  3RGO A;  3V0E A;  4YR8 B;  3EAX A;  2BIJ A;  1ZCK A;  1W7K A;  2VEW A;  2JJD A;  3B7O A;  3BLU A;  2G6Z A;  3EB1 A;  3O4T A;  4CVK A;  1RPM A;  3S3F A;  3OMH A;  1G1F A;  1Q1M A;  1NO6 A;  1ZCL A;  3RO1 A;  5BX1 A;  4DGX A;  2QBS A;  2VEV A;  2VEY A;  2QCJ A;  2I6J A;  2F6F A;  1NNY A;  4BPC A;  5A5E A;  2JFF A;  3MMJ A;  2Y96 A;  2GCA A;  1OET A;  2CJZ A;  3QCB A;  4RDD A;  4NX8 A;  4Y2E A;  2HC1 A;  2QBQ A;  5KA9 A;  1EEN A;  2NV5 A;  1C86 A;  4R0T A;  1G7G A;  2VOS A;  2JFH A;  4NYH A;  3F41 A;  4DGP A;  3S3H A;  4WU3 A;  2G59 A;  2AZR A;  1Q6J A;  2YDU A;  3ZM0 A;  2B49 A;  2I42 A;  1OEV A;  3D9C A;  2B07 A;  2I5X A;  2Q47 A;  2I6I A;  1NL9 A;  4PYH A;  2HNP A;  4GE6 A;  1J6U A;  1P3D A;  3LJ8 A;  2QCT A;  4QF5 A;  1YWF A;  4JMJ A;  1R6H A;  1YTW A;  1Q6N A;  2CNI A;  4C12 A;  3O4U A;  3CWE A;  2XPC A;  2HXP A;  4OHH A;  1G4U S;  4ZRT A;  2P4D A;  2HCM A;  2Y67 A;  3QCC A;  3BRH A;  1U25 A;  3BLT A;  4GFU A;  3V0I A;  2GWO A;  2QDM A;  2GCB A;  2VEU A;  3SR9 A;  2BGE A;  3D42 A;  2A8B A;  1VHR A;  3S4O A;  4OHD A;  1Q6S A;  2X5O A;  4Y14 A;  2CMB A;  4QUM A;  5BZZ A;  2Y68 A;  2CMC A;  5M43 A;  4CVL A;  1YN9 A;  2GJT A;  1Q6T A;  2B4P A;  2FJM A;  3M4U A;  1LAR A;  1V3A A;  2B4U A;  4HV4 A;  4GRY A;  3ZM1 A;  1RXD A;  2H4K A;  1M3G A;  1GFY A;  2PSZ A;  5KA2 A;  2QDC A;  5I6V A;  2NLK A;  1OEU A;  4H1O A;  4HRF A;  4BUB A;  2IMG A;  1PA9 A;  2QBP A;  2F6Z A;  2VTD A;  3A5K A;  3F9A A;  5KAA A;  3UAG A;  3ZM6 A;  1GWZ A;  5K25 A;  5KA4 A;  2J16 B;  5IBS A;  2CNH A;  2FJN A;  4KI9 A;  2F6W A;  3NRS A;  4RH5 A;  3D1H A;  1A5Y A;  4HJP A;  1XXP A;  4CVM A;  1ONZ A;  3I36 A;  1OES A;  2I3R A;  3N2A A;  3EU0 A;  5K9V A;  1YPT A;  4JBC A;  3MVN A;  2AHS A;  3QCN A;  4QAP A;  2BZL A;  3LK7 A;  5EHP A;  2CMA A;  3F9B A;  3RZ2 A;  1L8K A;  2Y66 A;  2I4E A;  4H34 A;  1LYV A;  2B3O A;  3D1O A;  5K23 A;  1YTN A;  1PTV A;  2PQ5 A;  1OHE A;  3QCJ A;  4GE5 A;  2DXP A;  4GS0 A;  2PI7 A;  2H4G A;  2VOR A;  4OHE A;  1EEH A;  1P15 A;  3V0G A;  3I80 A;  1E8C A;  3GXH A;  1T49 A;  3QCK A;  3PS5 A;  3U96 A;  2UUP A;  3PYZ A;  4PVG A;  2J16 A;  2H02 A;  5BUG A;  2I4G A;  4QBE A;  5K22 A;  5KA7 A;  4BJO A;  4RH9 A;  1ZZW A;  3ZM5 A;  2OUD A;  1NWL A;  4RHG A;  4GE2 A;  2I1Y A;  3QCI A;  3ZV2 A;  1C88 A;  3QCM A;  2HNQ A;  3D44 A;  2NT7 A;  2BV5 A;  2I6M A;  3BM8 A;  1JBW A;  2MBC A;  4MBB A;  2F70 A;  3GXG A;  4BUC A;  2GC6 A;  3QKP A;  3O4S A;  1T48 A;  4QBW A;  3I7Z A;  1FQ1 A;  3AWE A;  1U24 A;  1GQY A;  1BZH A;  3QCL A;  1QXK A;  5KAB A;  5KAD A;  1YGU A;  4QUN A;  2QEP A;  4NWF A;  2NT2 A;  1OEO X;  2M3V A;  5KA8 A;  2CFV A;  2OOQ A;  2C7S A;  2OC3 A;  1SUG A;  1MKP A;  5MMZ B;  2PT0 A;  4GFV A;  2QBR A;  4HJQ A;  3A5J A;  1C83 A;  4QAH A;  1G1H A;  1L8G A;  1LQF A;  2Q05 A;  2I4H A;  2QDP A;  2NZ6 A;  1JF7 A;  1PTU A;  4KYR A;  1I57 A;  3ZL8 A;  2GP0 A;  2F46 A;  3NME A;  5LXQ B;  3D1Q A;  2F6T A;  4WOH A;  4ZN5 A;  4RKK A;  4D3P A;  2OZ5 A;  4YAA A;  2F00 A;  2I75 A;  3S4E A;  2R0B A;  2Y1O A;  4ZI4 A;  3QCG A;  4RI4 A;  1G1G A;  3QCD A;  1XBO A;  5EHR A;  1PTY A;  2ZN7 A;  2RF6 A;  4WU2 A;  4OHI A;  1X24 A;  4IKC A;  5K24 A;  2CM7 A;  2Y2F A;  1OHD A;  3AWF A;  3O3L A;  4NWG A;  4C13 A;  4ERC A;  5IBM A;  2E0T A;  5K9W A;  3QCE A;  2BGD A;  2GC5 A;  3QCZ A;  4GWF A;  2CM3 A;  2FH7 A;  4Z6B A;  2I6P A;  5HDE A;  1C85 A;  3N0A A;  3SME A;  2A3K A;  1XXV A;  1C84 A;  1YTS A;  1C87 A;  2F6V A;  1YZ4 A;  1Q6P A;  1Q6M A;  1FPZ A;  2XJA A;  1J4X A;  1KAV A;  3AWG A;  5KA0 A;  1I9T A;  2J17 A;  2UUO A;  3CM3 A;  2CNE A;  2VTE A;  3ZMQ A;  2F71 A;  4S0G A;  3F99 A;  3QCH A;  1ONY A;  1I9S A;  1G7F A;  2JFG A;  1EEO A;  3V0F A;  2CM2 A;  5KAC A;  4J51 A;  1GG4 A;  2I3U A;  2HVL A;  1NZ7 A;  4AZ1 A;  3H2X A;  3EZZ A;  4R30 A;  2WTZ A;  1BZC A;  4NND A;  2I6O A;  3F81 A;  3QKQ A;  3V0J A;  4B04 A;  3EMU A;  1UAG A;  2PBN A;  5KA1 A;  4RI5 A;  2AM2 A;  4JMK A;  1FGS A;  1G4W R;  2WGP A;  2UAG A;  2WJP A;  4I8N A;  2HY3 A;  4D3Q A;  3S3K A;  2ESB A;  3MOZ A;  1WAX A;  2F6Y A;  1WCH A;  2H04 A;  2ZMM A;  5BZX A;  2P6X A;  1QZ0 A;  4TVV A;  1NWE A;  1OHC A;  1ZC0 A;  4UAG A;  2CNF A;  3MOW A;  4ZIY A;  4QDI A;  4OHL A;  1D5R A;  1FPR A;  2HB1 A;  1WRM A;  2VEX A;  1P31 A;  3ZM2 A;  3QCF A;  5J8R A;  1PTT A;  1O5Z A;  4WTY A;  2CM8 A;  2H03 A;  5A5F A;  1JLN A;  3V0D A;  1PA1 A;  3HN7 A;  1XM2 A;  4KYQ A;  4ICZ A;  1KAK A;  3ZM3 A;  1YGR A;  1PYN A;  1OEM X;  4GRZ A;  3S3E A;  2H4V A;  1PXH A;  3RGQ A;  4D3R A;  2B4O A;  1XRI A;  2SHP A;  2B4S A;  5KA3 A;  3ZMP A;  3V0H A;  3OLR A;  1T4J A;  5GTJ A;  1GQQ A;  1PH0 A;  1JBV A;  1W78 A;  3O5X A;  2NTA A;  2C46 A;  2CNG A; 
#chains in the Genus database with same CATH homology
 1AAX A;  1U26 A;  2PA5 A;  5AWX A;  4R0S A;  1BZJ A;  2HC2 A;  1ECV A;  1YFO A;  4JNB A;  3RGO A;  3V0E A;  4YR8 B;  3EAX A;  2BIJ A;  1ZCK A;  2VEW A;  2JJD A;  3B7O A;  3BLU A;  2G6Z A;  3EB1 A;  3O4T A;  1RPM A;  3S3F A;  3OMH A;  1G1F A;  1Q1M A;  1NO6 A;  1ZCL A;  3RO1 A;  5BX1 A;  4DGX A;  2QBS A;  2VEV A;  2VEY A;  2QCJ A;  2I6J A;  2F6F A;  1NNY A;  4BPC A;  3MMJ A;  2Y96 A;  1OET A;  2CJZ A;  3QCB A;  4RDD A;  4NX8 A;  4Y2E A;  2HC1 A;  2QBQ A;  5KA9 A;  1EEN A;  2NV5 A;  1C86 A;  4R0T A;  1G7G A;  4NYH A;  3F41 A;  4DGP A;  3S3H A;  4WU3 A;  2G59 A;  2AZR A;  1Q6J A;  2YDU A;  3ZM0 A;  2B49 A;  2I42 A;  1OEV A;  2I5X A;  2B07 A;  3D9C A;  2Q47 A;  2I6I A;  1NL9 A;  4PYH A;  2HNP A;  4GE6 A;  3LJ8 A;  2QCT A;  1YWF A;  4JMJ A;  1R6H A;  1YTW A;  1Q6N A;  2CNI A;  3O4U A;  3CWE A;  2HXP A;  4OHH A;  1G4U S;  4ZRT A;  2P4D A;  2HCM A;  3QCC A;  3BRH A;  1U25 A;  3BLT A;  4GFU A;  3V0I A;  2GWO A;  2QDM A;  2VEU A;  3SR9 A;  2BGE A;  3D42 A;  2A8B A;  1VHR A;  3S4O A;  4OHD A;  1Q6S A;  4Y14 A;  2CMB A;  4QUM A;  5BZZ A;  2CMC A;  5M43 A;  1YN9 A;  2GJT A;  1Q6T A;  2B4P A;  2FJM A;  3M4U A;  1LAR A;  1V3A A;  2B4U A;  4GRY A;  3ZM1 A;  1RXD A;  2H4K A;  1M3G A;  1GFY A;  2PSZ A;  5KA2 A;  2QDC A;  5I6V A;  2NLK A;  1OEU A;  4H1O A;  4HRF A;  2IMG A;  1PA9 A;  2QBP A;  2F6Z A;  3A5K A;  3F9A A;  5KAA A;  1GWZ A;  5K25 A;  5KA4 A;  2J16 B;  5IBS A;  2CNH A;  2FJN A;  4KI9 A;  2F6W A;  4RH5 A;  3D1H A;  1A5Y A;  4HJP A;  1XXP A;  1ONZ A;  3I36 A;  1OES A;  2I3R A;  3EU0 A;  5K9V A;  1YPT A;  4JBC A;  2AHS A;  3QCN A;  4QAP A;  2BZL A;  5EHP A;  2CMA A;  3F9B A;  3RZ2 A;  1L8K A;  2I4E A;  4H34 A;  1LYV A;  2B3O A;  3D1O A;  5K23 A;  1YTN A;  1PTV A;  2PQ5 A;  1OHE A;  3QCJ A;  4GE5 A;  2DXP A;  4GS0 A;  2PI7 A;  2H4G A;  4OHE A;  1P15 A;  3V0G A;  3I80 A;  3GXH A;  1T49 A;  3QCK A;  3PS5 A;  3U96 A;  4PVG A;  2J16 A;  2H02 A;  5BUG A;  2I4G A;  4QBE A;  5K22 A;  5KA7 A;  4BJO A;  4RH9 A;  1ZZW A;  2OUD A;  1NWL A;  4RHG A;  4GE2 A;  2I1Y A;  3QCI A;  3ZV2 A;  1C88 A;  3QCM A;  2HNQ A;  3D44 A;  2NT7 A;  2BV5 A;  2I6M A;  3BM8 A;  2MBC A;  4MBB A;  2F70 A;  3GXG A;  3QKP A;  3O4S A;  1T48 A;  4QBW A;  3I7Z A;  1FQ1 A;  3AWE A;  1U24 A;  1BZH A;  3QCL A;  1QXK A;  5KAB A;  5KAD A;  1YGU A;  4QUN A;  2QEP A;  4NWF A;  2NT2 A;  1OEO X;  2M3V A;  5KA8 A;  2CFV A;  2OOQ A;  2C7S A;  2OC3 A;  1SUG A;  1MKP A;  5MMZ B;  2PT0 A;  4GFV A;  2QBR A;  4HJQ A;  3A5J A;  1C83 A;  4QAH A;  1G1H A;  1L8G A;  1LQF A;  2Q05 A;  2I4H A;  2QDP A;  2NZ6 A;  1JF7 A;  1PTU A;  4KYR A;  1I57 A;  2GP0 A;  2F46 A;  3NME A;  5LXQ B;  3D1Q A;  2F6T A;  4WOH A;  4ZN5 A;  4RKK A;  4D3P A;  2OZ5 A;  4YAA A;  2I75 A;  3S4E A;  2R0B A;  4ZI4 A;  3QCG A;  4RI4 A;  1G1G A;  3QCD A;  1XBO A;  5EHR A;  1PTY A;  2ZN7 A;  2RF6 A;  4WU2 A;  4OHI A;  1X24 A;  4IKC A;  5K24 A;  2CM7 A;  2Y2F A;  1OHD A;  3AWF A;  3O3L A;  4NWG A;  4ERC A;  5IBM A;  2E0T A;  5K9W A;  3QCE A;  2BGD A;  4GWF A;  2CM3 A;  2FH7 A;  4Z6B A;  2I6P A;  5HDE A;  1C85 A;  3N0A A;  3SME A;  2A3K A;  1XXV A;  1C84 A;  1YTS A;  1C87 A;  2F6V A;  1YZ4 A;  1Q6P A;  1Q6M A;  1FPZ A;  1J4X A;  1KAV A;  3AWG A;  5KA0 A;  1I9T A;  2J17 A;  3CM3 A;  2CNE A;  3ZMQ A;  2F71 A;  4S0G A;  3F99 A;  3QCH A;  1ONY A;  1I9S A;  1G7F A;  1EEO A;  3V0F A;  2CM2 A;  5KAC A;  4J51 A;  2I3U A;  2HVL A;  1NZ7 A;  4AZ1 A;  3H2X A;  3EZZ A;  4R30 A;  1BZC A;  4NND A;  2I6O A;  3F81 A;  3QKQ A;  3V0J A;  4B04 A;  3EMU A;  2PBN A;  5KA1 A;  4RI5 A;  4JMK A;  1G4W R;  2WGP A;  4I8N A;  2HY3 A;  4D3Q A;  3S3K A;  2ESB A;  3MOZ A;  1WAX A;  2F6Y A;  1WCH A;  2H04 A;  2ZMM A;  5BZX A;  2P6X A;  1QZ0 A;  4TVV A;  1NWE A;  1OHC A;  1ZC0 A;  2CNF A;  3MOW A;  4OHL A;  1D5R A;  1FPR A;  2HB1 A;  1WRM A;  2VEX A;  3ZM2 A;  3QCF A;  5J8R A;  1PTT A;  4WTY A;  2CM8 A;  2H03 A;  1JLN A;  3V0D A;  1PA1 A;  1XM2 A;  4KYQ A;  4ICZ A;  1KAK A;  3ZM3 A;  1YGR A;  1PYN A;  1OEM X;  4GRZ A;  3S3E A;  2H4V A;  1PXH A;  3RGQ A;  4D3R A;  2B4O A;  1XRI A;  2SHP A;  2B4S A;  5KA3 A;  3ZMP A;  3V0H A;  3OLR A;  1T4J A;  5GTJ A;  1PH0 A;  3O5X A;  2NTA A;  2C46 A;  2CNG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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