2F70A

Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase, non-receptor type 1
total genus 108
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2005-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2f70A00
2FJMA 3QKQA 1GFYA 2M3VA 4JBCA 1I9TA 1PTTA 1ZC0A 3H2XA 3EAXA 4OHIA 2GJTA 2AZRA 3D42A 1XM2A 2CMCA 3BRHA 2F70A 1Q1MA 2PQ5A 2HC1A 1PYNA 1OETA 1G4WR 3RGQA 2I3UA 2QEPA 1G7GA 2QBQA 4YR8B 3S4EA 2F6VA 2B49A 5IBSA 2IMGA 5BX1A 5I6VA 2VEUA 3I80A 1I57A 3F9BA 2HNPA 2I6OA 2NTAA 2NZ6A 3CWEA 4D3RA 3EB1A 3A5KA 4RH9A 1J4XA 3V0IA 2I4GA 4RKKA 1EENA 3QCMA 2F6WA 3A5JA 2QCJA 1G4US 1L8GA 1G7FA 5KA0A 2H04A 4H1OA 2C7SA 1X24A 4J51A 1XBOA 3QCBA 4GE6A 1OHDA 2A3KA 3S3KA 4OHEA 2CNIA 2B4OA 3I7ZA 2PT0A 3D1QA 5KA3A 2CMBA 5AWXA 2QDPA 2VEWA 2WGPA 2HB1A 1PA1A 1BZJA 2HCMA 3QCHA 1C85A 1OHEA 2F6YA 3EZZA 4JMKA 3ZMQA 1YWFA 4GFUA 3D44A 2PI7A 4HJQA 3U96A 5KA2A 3GXGA 4IKCA 1PA9A 2QBSA 3D1OA 2BGDA 3V0JA 1R6HA 5K22A 1FPRA 3ZM1A 5K23A 1MKPA 4GRYA 3F9AA 1EEOA 2BV5A 1T49A 3QKPA 5KADA 1YN9A 5KA4A 2BIJA 2ESBA 1NL9A 1XRIA 1PTUA 1SUGA 1BZCA 4OHLA 4BPCA 2NT2A 4JNBA 4ERCA 2CNHA 3QCIA 3EU0A 2FJNA 1YZ4A 2YDUA 1U25A 2B4SA 2CM8A 4NX8A 5K9VA 1C87A 2Y96A 4AZ1A 1G1FA 4RH5A 2A8BA 4NNDA 4R30A 2BZLA 3LJ8A 2DXPA 1P15A 2I5XA 1YFOA 3V0EA 3ZMPA 1KAVA 3S3FA 2J16B 3O3LA 3BLUA 4MBBA 2OUDA 5K24A 4NWFA 2ZN7A 1KAKA 3SR9A 1BZHA 4NWGA 1Q6NA 5IBMA 1Q6MA 4BJOA 1FPZA 5HDEA 2MBCA 2CM3A 1Q6SA 2JJDA 2H4VA 1I9SA 4ZRTA 1OEUA 2VEXA 3QCNA 3PS5A 3NMEA 2NV5A 4DGXA 4WTYA 3QCKA 1OHCA 2F46A 1YTSA 2F6ZA 2RF6A 1D5RA 1NO6A 5KABA 4Y14A 1M3GA 3BLTA 2B07A 1T48A 1ONZA 4PYHA 1WAXA 5GTJA 1PTYA 5KA8A 3RZ2A 4R0TA 3OLRA 5BZZA 2I6JA 4PVGA 3V0GA 2I4EA 3QCFA 2J16A 2NLKA 2P4DA 4ICZA 2Y2FA 4R0SA 1YGUA 5J8RA 3SMEA 2B3OA 1OEOX 3QCGA 4WOHA 5LXQB 3F81A 2CFVA 3GXHA 5EHRA 3S4OA 1ZZWA 4QUMA 2B4PA 2QCTA 2CMAA 4JMJA 3S3EA 4DGPA 2GWOA 3QCLA 2SHPA 2H02A 2FH7A 3M4UA 4OHDA 1C88A 3QCDA 2CNEA 2I3RA 4D3PA 4KYQA 2F71A 4Y2EA 2R0BA 3AWEA 4QUNA 2PBNA 5KAAA 2NT7A 2OZ5A 4RI5A 2J17A 3V0DA 5MMZB 4GFVA 1JF7A 4QBEA 5EHPA 2I1YA 2H03A 1Q6TA 5KA1A 2I75A 4QAHA 3V0FA 2BGEA 1WRMA 2I6PA 1YGRA 2C46A 4TVVA 3V0HA 1ZCLA 1NWEA 5BZXA 1NNYA 2H4GA 1QXKA 4GE2A 1T4JA 4ZN5A 4GE5A 2I4HA 1PXHA 2I42A 1XXPA 3MOZA 1RXDA 1YTWA 2VEVA 2GP0A 2CM7A 5KA9A 2HNQA 4S0GA 4I8NA 4YAAA 2ZMMA 1GWZA 2QDMA 3ZM2A 1XXVA 1RPMA 1Q6JA 2P6XA 5KACA 2Q47A 1U24A 4KYRA 3D9CA 4HRFA 1G1HA 1ECVA 1V3AA 2QBPA 1L8KA 3OMHA 3O4UA 2OOQA 1LARA 4WU2A 1YTNA 3QCJA 1U26A 2E0TA 3AWGA 3O4TA 5K25A 5K9WA 2PSZA 3QCCA 1NWLA 2QBRA 1AAXA 1OEMX 1VHRA 4QAPA 2F6FA 1PTVA 3O5XA 3MOWA 2HXPA 3N0AA 4RHGA 2CNGA 1A5YA 4RI4A 3QCEA 3F41A 1JLNA 5M43A 2QDCA 1LYVA 1ONYA 4ZI4A 1YPTA 3MMJA 3RGOA 2HC2A 3B7OA 4B04A 1C86A 1WCHA 4QBWA 1QZ0A 2I6IA 3CM3A 3RO1A 3ZM3A 1OEVA 1OESA 1ZCKA 3ZV2A 2HVLA 1G1GA 2OC3A 3D1HA 2CJZA 4RDDA 4OHHA 4KI9A 1LQFA 2F6TA 1PH0A 2AHSA 4H34A 2VEYA 2B4UA 3S3HA 3BM8A 3EMUA 5KA7A 2I6MA 2G59A 4GWFA 4NYHA 4HJPA 2CNFA 4GRZA 2HY3A 2Q05A 3I36A 5BUGA 3O4SA 1NZ7A 1C84A 2CM2A 3AWFA 2H4KA 4Z6BA 4WU3A 1FQ1A 1Q6PA 3F99A 3ZM0A 4GS0A 1C83A 2PA5A 2G6ZA 4D3QA
chains in the Genus database with same CATH superfamily
2FJMA 3QKQA 1GFYA 2M3VA 4JBCA 1I9TA 1PTTA 1ZC0A 3MVNA 3H2XA 3EAXA 4OHIA 2GJTA 3UAGA 2GCAA 2AZRA 3D42A 1XM2A 2CMCA 3BRHA 2F70A 1Q1MA 2PQ5A 2HC1A 1PYNA 2Y68A 1OETA 1G4WR 1JBWA 3RGQA 2I3UA 2QEPA 1G7GA 4CVMA 3N2AA 2VTDA 2QBQA 4YR8B 3S4EA 1O5ZA 2F6VA 2B49A 5IBSA 2IMGA 5BX1A 5I6VA 2VEUA 3I80A 1I57A 3F9BA 2HNPA 2UAGA 2I6OA 2NTAA 2NZ6A 3CWEA 4D3RA 3EB1A 3A5KA 4RH9A 1J4XA 3V0IA 2I4GA 4RKKA 1EENA 3QCMA 2F6WA 3A5JA 2QCJA 1G4US 1L8GA 1G7FA 5A5FA 5KA0A 2H04A 4H1OA 2C7SA 1X24A 4J51A 1XBOA 3QCBA 4GE6A 1OHDA 2A3KA 3S3KA 4OHEA 2CNIA 2B4OA 1P31A 3I7ZA 2WTZA 2PT0A 3D1QA 5KA3A 2CMBA 5AWXA 2QDPA 2F00A 2VEWA 2WGPA 1FGSA 2HB1A 1PA1A 1BZJA 2HCMA 3QCHA 1C85A 2WJPA 1OHEA 2F6YA 3EZZA 4BUBA 4JMKA 3ZMQA 2GC6A 2Y66A 1YWFA 4GFUA 4CVLA 3D44A 2PI7A 4HJQA 3U96A 5KA2A 3GXGA 4IKCA 1PA9A 2X5OA 2QBSA 3D1OA 2JFHA 2BGDA 3V0JA 1R6HA 5K22A 1FPRA 3ZM1A 5K23A 1MKPA 2AM2A 3F9AA 4GRYA 1EEOA 2BV5A 1T49A 3QKPA 5KADA 1YN9A 5KA4A 2BIJA 2ESBA 1NL9A 1XRIA 1PTUA 1SUGA 1BZCA 4OHLA 4BPCA 2NT2A 4C12A 4JNBA 4ERCA 2CNHA 3QCIA 2XPCA 3EU0A 2FJNA 1YZ4A 2JFFA 2YDUA 1U25A 2B4SA 2CM8A 4NX8A 4QF5A 5K9VA 1C87A 2Y96A 2GCBA 4AZ1A 1G1FA 4RH5A 2A8BA 4NNDA 4R30A 2BZLA 3LJ8A 3ZL8A 2DXPA 1JBVA 1P15A 2I5XA 1GQYA 4C13A 1YFOA 3V0EA 3ZMPA 1KAVA 3S3FA 2J16B 3O3LA 3BLUA 4MBBA 2OUDA 1GG4A 5K24A 4NWFA 4QDIA 2ZN7A 1KAKA 3SR9A 1BZHA 4NWGA 1GQQA 1Q6NA 5IBMA 1Q6MA 4BJOA 1FPZA 3HN7A 5HDEA 2MBCA 2CM3A 1Q6SA 2JJDA 2H4VA 1I9SA 4ZRTA 1OEUA 2Y1OA 2VEXA 3QCNA 3PS5A 3NMEA 2NV5A 4DGXA 4WTYA 3QCKA 1OHCA 2F46A 1YTSA 2F6ZA 2VTEA 1E8CA 2RF6A 1D5RA 1NO6A 5KABA 4Y14A 1M3GA 3BLTA 2B07A 1T48A 1ONZA 4PYHA 1WAXA 5GTJA 1PTYA 5KA8A 3RZ2A 4R0TA 3NRSA 3OLRA 5BZZA 2I6JA 4PVGA 3V0GA 1EEHA 2I4EA 3PYZA 3QCFA 2J16A 2NLKA 2P4DA 4ICZA 4ZIYA 2Y2FA 4R0SA 1YGUA 5J8RA 3SMEA 2B3OA 1OEOX 3QCGA 4WOHA 2XJAA 5LXQB 3F81A 2CFVA 3GXHA 5EHRA 3S4OA 1ZZWA 4QUMA 2B4PA 2QCTA 2CMAA 4JMJA 3S3EA 4DGPA 2GWOA 3QCLA 2SHPA 2H02A 2FH7A 3M4UA 4OHDA 2VOSA 1C88A 3QCDA 2CNEA 2I3RA 4D3PA 4KYQA 2F71A 4Y2EA 2R0BA 3AWEA 4QUNA 2PBNA 5KAAA 2NT7A 1W7KA 2OZ5A 4RI5A 2J17A 3V0DA 3QCZA 5MMZB 4GFVA 1JF7A 4QBEA 5EHPA 2JFGA 2I1YA 2H03A 1Q6TA 5KA1A 2I75A 4QAHA 3V0FA 2BGEA 3ZM5A 1J6UA 1WRMA 2I6PA 1YGRA 2C46A 4TVVA 3V0HA 1ZCLA 1NWEA 5BZXA 1NNYA 2H4GA 1QXKA 4GE2A 1T4JA 4ZN5A 2AM1A 4GE5A 2I4HA 1PXHA 2I42A 1XXPA 3MOZA 1RXDA 1YTWA 2VEVA 5A5EA 2GP0A 2CM7A 5KA9A 2HNQA 4S0GA 4I8NA 4YAAA 2ZMMA 1GWZA 2QDMA 3ZM2A 1XXVA 1RPMA 1Q6JA 2P6XA 4BUCA 5KACA 2Q47A 1U24A 4KYRA 3D9CA 4HRFA 1G1HA 1ECVA 1V3AA 2QBPA 1L8KA 3OMHA 1P3DA 2VORA 3O4UA 1E0DA 2OOQA 1LARA 4WU2A 1YTNA 3QCJA 1U26A 2E0TA 3AWGA 3O4TA 5K25A 5K9WA 2PSZA 3QCCA 1NWLA 2QBRA 1AAXA 1OEMX 1VHRA 4QAPA 2F6FA 1PTVA 3O5XA 3MOWA 2HXPA 3N0AA 4RHGA 2CNGA 1A5YA 4RI4A 3QCEA 4HV4A 3F41A 1JLNA 5M43A 2QDCA 1LYVA 1ONYA 4ZI4A 1W78A 1YPTA 3MMJA 3RGOA 2HC2A 3B7OA 4B04A 4CVKA 1C86A 1WCHA 4QBWA 1QZ0A 2I6IA 3CM3A 3RO1A 3ZM3A 1OEVA 1OESA 1ZCKA 3ZV2A 2HVLA 1G1GA 3LK7A 2OC3A 3D1HA 2CJZA 4RDDA 4OHHA 4KI9A 1LQFA 2F6TA 1PH0A 2AHSA 4H34A 2VEYA 1UAGA 2B4UA 4UAGA 3S3HA 3BM8A 2GC5A 3EMUA 5KA7A 2I6MA 2G59A 4GWFA 4NYHA 4HJPA 2CNFA 4GRZA 2HY3A 2Q05A 3ZM6A 3I36A 5BUGA 3O4SA 1NZ7A 1C84A 2CM2A 3AWFA 2H4KA 4Z6BA 4WU3A 1FQ1A 2UUPA 1Q6PA 2Y67A 3F99A 3ZM0A 2UUOA 4GS0A 1C83A 2PA5A 2G6ZA 4D3QA
chains in the Genus database with same CATH topology
2FJMA 3QKQA 1GFYA 2M3VA 4JBCA 1I9TA 1PTTA 1ZC0A 3H2XA 3EAXA 4OHIA 2GJTA 2AZRA 3D42A 1XM2A 2CMCA 3BRHA 2F70A 1Q1MA 2PQ5A 2HC1A 1PYNA 1OETA 1G4WR 3RGQA 2I3UA 2QEPA 1G7GA 2QBQA 4YR8B 3S4EA 2F6VA 2B49A 5IBSA 2IMGA 5BX1A 5I6VA 2VEUA 3I80A 1I57A 3F9BA 2HNPA 2I6OA 2NTAA 2NZ6A 3CWEA 4D3RA 3EB1A 3A5KA 4RH9A 1J4XA 3V0IA 2I4GA 4RKKA 1EENA 3QCMA 2F6WA 3A5JA 2QCJA 1G4US 1L8GA 1G7FA 5KA0A 2H04A 4H1OA 2C7SA 1X24A 4J51A 1XBOA 3QCBA 4GE6A 1OHDA 2A3KA 3S3KA 4OHEA 2CNIA 2B4OA 3I7ZA 2PT0A 3D1QA 5KA3A 2CMBA 5AWXA 2QDPA 2VEWA 2WGPA 2HB1A 1PA1A 1BZJA 2HCMA 3QCHA 1C85A 1OHEA 2F6YA 3EZZA 4JMKA 3ZMQA 1YWFA 4GFUA 3D44A 2PI7A 4HJQA 3U96A 5KA2A 3GXGA 4IKCA 1PA9A 2QBSA 3D1OA 2BGDA 3V0JA 1R6HA 5K22A 1FPRA 3ZM1A 5K23A 1MKPA 4GRYA 3F9AA 1EEOA 2BV5A 1T49A 3QKPA 5KADA 1YN9A 5KA4A 2BIJA 2ESBA 1NL9A 1XRIA 1PTUA 1SUGA 1BZCA 4OHLA 4BPCA 2NT2A 4JNBA 4ERCA 2CNHA 3QCIA 3EU0A 2FJNA 1YZ4A 2YDUA 1U25A 2B4SA 2CM8A 4NX8A 5K9VA 1C87A 2Y96A 4AZ1A 1G1FA 4RH5A 2A8BA 4NNDA 4R30A 2BZLA 3LJ8A 2DXPA 1P15A 2I5XA 1YFOA 3V0EA 3ZMPA 1KAVA 3S3FA 2J16B 3O3LA 3BLUA 4MBBA 2OUDA 5K24A 4NWFA 2ZN7A 1KAKA 3SR9A 1BZHA 4NWGA 1Q6NA 5IBMA 1Q6MA 4BJOA 1FPZA 5HDEA 2MBCA 2CM3A 1Q6SA 2JJDA 2H4VA 1I9SA 4ZRTA 1OEUA 2VEXA 3QCNA 3PS5A 3NMEA 2NV5A 4DGXA 4WTYA 3QCKA 1OHCA 2F46A 1YTSA 2F6ZA 2RF6A 1D5RA 1NO6A 5KABA 4Y14A 1M3GA 3BLTA 2B07A 1T48A 1ONZA 4PYHA 1WAXA 5GTJA 1PTYA 5KA8A 3RZ2A 4R0TA 3OLRA 5BZZA 2I6JA 4PVGA 3V0GA 2I4EA 3QCFA 2J16A 2NLKA 2P4DA 4ICZA 2Y2FA 4R0SA 1YGUA 5J8RA 3SMEA 2B3OA 1OEOX 3QCGA 4WOHA 5LXQB 3F81A 2CFVA 3GXHA 5EHRA 3S4OA 1ZZWA 4QUMA 2B4PA 2QCTA 2CMAA 4JMJA 3S3EA 4DGPA 2GWOA 3QCLA 2SHPA 2H02A 2FH7A 3M4UA 4OHDA 1C88A 3QCDA 2CNEA 2I3RA 4D3PA 4KYQA 2F71A 4Y2EA 2R0BA 3AWEA 4QUNA 2PBNA 5KAAA 2NT7A 2OZ5A 4RI5A 2J17A 3V0DA 5MMZB 4GFVA 1JF7A 4QBEA 5EHPA 2I1YA 2H03A 1Q6TA 5KA1A 2I75A 4QAHA 3V0FA 2BGEA 1WRMA 2I6PA 1YGRA 2C46A 4TVVA 3V0HA 1ZCLA 1NWEA 5BZXA 1NNYA 2H4GA 1QXKA 4GE2A 1T4JA 4ZN5A 4GE5A 2I4HA 1PXHA 2I42A 1XXPA 3MOZA 1RXDA 1YTWA 2VEVA 2GP0A 2CM7A 5KA9A 2HNQA 4S0GA 4I8NA 4YAAA 2ZMMA 1GWZA 2QDMA 3ZM2A 1XXVA 1RPMA 1Q6JA 2P6XA 5KACA 2Q47A 1U24A 4KYRA 3D9CA 4HRFA 1G1HA 1ECVA 1V3AA 2QBPA 1L8KA 3OMHA 3O4UA 2OOQA 1LARA 4WU2A 1YTNA 3QCJA 1U26A 2E0TA 3AWGA 3O4TA 5K25A 5K9WA 2PSZA 3QCCA 1NWLA 2QBRA 1AAXA 1OEMX 1VHRA 4QAPA 2F6FA 1PTVA 3O5XA 3MOWA 2HXPA 3N0AA 4RHGA 2CNGA 1A5YA 4RI4A 3QCEA 3F41A 1JLNA 5M43A 2QDCA 1LYVA 1ONYA 4ZI4A 1YPTA 3MMJA 3RGOA 2HC2A 3B7OA 4B04A 1C86A 1WCHA 4QBWA 1QZ0A 2I6IA 3CM3A 3RO1A 3ZM3A 1OEVA 1OESA 1ZCKA 3ZV2A 2HVLA 1G1GA 2OC3A 3D1HA 2CJZA 4RDDA 4OHHA 4KI9A 1LQFA 2F6TA 1PH0A 2AHSA 4H34A 2VEYA 2B4UA 3S3HA 3BM8A 3EMUA 5KA7A 2I6MA 2G59A 4GWFA 4NYHA 4HJPA 2CNFA 4GRZA 2HY3A 2Q05A 3I36A 5BUGA 3O4SA 1NZ7A 1C84A 2CM2A 3AWFA 2H4KA 4Z6BA 4WU3A 1FQ1A 1Q6PA 3F99A 3ZM0A 4GS0A 1C83A 2PA5A 2G6ZA 4D3QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FJM A;  3QKQ A;  1GFY A;  2M3V A;  4JBC A;  1I9T A;  1PTT A;  1ZC0 A;  3H2X A;  3EAX A;  4OHI A;  2GJT A;  2AZR A;  3D42 A;  1XM2 A;  2CMC A;  3BRH A;  2F70 A;  1Q1M A;  2PQ5 A;  2HC1 A;  1PYN A;  1OET A;  1G4W R;  3RGQ A;  2I3U A;  2QEP A;  1G7G A;  2QBQ A;  4YR8 B;  3S4E A;  2F6V A;  2B49 A;  5IBS A;  2IMG A;  5BX1 A;  5I6V A;  2VEU A;  3I80 A;  1I57 A;  3F9B A;  2HNP A;  2I6O A;  2NTA A;  2NZ6 A;  3CWE A;  4D3R A;  3EB1 A;  3A5K A;  4RH9 A;  1J4X A;  3V0I A;  2I4G A;  4RKK A;  1EEN A;  3QCM A;  2F6W A;  3A5J A;  2QCJ A;  1G4U S;  1L8G A;  1G7F A;  5KA0 A;  2H04 A;  4H1O A;  2C7S A;  1X24 A;  4J51 A;  1XBO A;  3QCB A;  4GE6 A;  1OHD A;  2A3K A;  3S3K A;  4OHE A;  2CNI A;  2B4O A;  3I7Z A;  2PT0 A;  3D1Q A;  5KA3 A;  2CMB A;  5AWX A;  2QDP A;  2VEW A;  2WGP A;  2HB1 A;  1PA1 A;  1BZJ A;  2HCM A;  3QCH A;  1C85 A;  1OHE A;  2F6Y A;  3EZZ A;  4JMK A;  3ZMQ A;  1YWF A;  4GFU A;  3D44 A;  2PI7 A;  4HJQ A;  3U96 A;  5KA2 A;  3GXG A;  4IKC A;  1PA9 A;  2QBS A;  3D1O A;  2BGD A;  3V0J A;  1R6H A;  5K22 A;  1FPR A;  3ZM1 A;  5K23 A;  1MKP A;  4GRY A;  3F9A A;  1EEO A;  2BV5 A;  1T49 A;  3QKP A;  5KAD A;  1YN9 A;  5KA4 A;  2BIJ A;  2ESB A;  1NL9 A;  1XRI A;  1PTU A;  1SUG A;  1BZC A;  4OHL A;  4BPC A;  2NT2 A;  4JNB A;  4ERC A;  2CNH A;  3QCI A;  3EU0 A;  2FJN A;  1YZ4 A;  2YDU A;  1U25 A;  2B4S A;  2CM8 A;  4NX8 A;  5K9V A;  1C87 A;  2Y96 A;  4AZ1 A;  1G1F A;  4RH5 A;  2A8B A;  4NND A;  4R30 A;  2BZL A;  3LJ8 A;  2DXP A;  1P15 A;  2I5X A;  1YFO A;  3V0E A;  3ZMP A;  1KAV A;  3S3F A;  2J16 B;  3O3L A;  3BLU A;  4MBB A;  2OUD A;  5K24 A;  4NWF A;  2ZN7 A;  1KAK A;  3SR9 A;  1BZH A;  4NWG A;  1Q6N A;  5IBM A;  1Q6M A;  4BJO A;  1FPZ A;  5HDE A;  2MBC A;  2CM3 A;  1Q6S A;  2JJD A;  2H4V A;  1I9S A;  4ZRT A;  1OEU A;  2VEX A;  3QCN A;  3PS5 A;  3NME A;  2NV5 A;  4DGX A;  4WTY A;  3QCK A;  1OHC A;  2F46 A;  1YTS A;  2F6Z A;  2RF6 A;  1D5R A;  1NO6 A;  5KAB A;  4Y14 A;  1M3G A;  3BLT A;  2B07 A;  1T48 A;  1ONZ A;  4PYH A;  1WAX A;  5GTJ A;  1PTY A;  5KA8 A;  3RZ2 A;  4R0T A;  3OLR A;  5BZZ A;  2I6J A;  4PVG A;  3V0G A;  2I4E A;  3QCF A;  2J16 A;  2NLK A;  2P4D A;  4ICZ A;  2Y2F A;  4R0S A;  1YGU A;  5J8R A;  3SME A;  2B3O A;  1OEO X;  3QCG A;  4WOH A;  5LXQ B;  3F81 A;  2CFV A;  3GXH A;  5EHR A;  3S4O A;  1ZZW A;  4QUM A;  2B4P A;  2QCT A;  2CMA A;  4JMJ A;  3S3E A;  4DGP A;  2GWO A;  3QCL A;  2SHP A;  2H02 A;  2FH7 A;  3M4U A;  4OHD A;  1C88 A;  3QCD A;  2CNE A;  2I3R A;  4D3P A;  4KYQ A;  2F71 A;  4Y2E A;  2R0B A;  3AWE A;  4QUN A;  2PBN A;  5KAA A;  2NT7 A;  2OZ5 A;  4RI5 A;  2J17 A;  3V0D A;  5MMZ B;  4GFV A;  1JF7 A;  4QBE A;  5EHP A;  2I1Y A;  2H03 A;  1Q6T A;  5KA1 A;  2I75 A;  4QAH A;  3V0F A;  2BGE A;  1WRM A;  2I6P A;  1YGR A;  2C46 A;  4TVV A;  3V0H A;  1ZCL A;  1NWE A;  5BZX A;  1NNY A;  2H4G A;  1QXK A;  4GE2 A;  1T4J A;  4ZN5 A;  4GE5 A;  2I4H A;  1PXH A;  2I42 A;  1XXP A;  3MOZ A;  1RXD A;  1YTW A;  2VEV A;  2GP0 A;  2CM7 A;  5KA9 A;  2HNQ A;  4S0G A;  4I8N A;  4YAA A;  2ZMM A;  1GWZ A;  2QDM A;  3ZM2 A;  1XXV A;  1RPM A;  1Q6J A;  2P6X A;  5KAC A;  2Q47 A;  1U24 A;  4KYR A;  3D9C A;  4HRF A;  1G1H A;  1ECV A;  1V3A A;  2QBP A;  1L8K A;  3OMH A;  3O4U A;  2OOQ A;  1LAR A;  4WU2 A;  1YTN A;  3QCJ A;  1U26 A;  2E0T A;  3AWG A;  3O4T A;  5K25 A;  5K9W A;  2PSZ A;  3QCC A;  1NWL A;  2QBR A;  1AAX A;  1OEM X;  1VHR A;  4QAP A;  2F6F A;  1PTV A;  3O5X A;  3MOW A;  2HXP A;  3N0A A;  4RHG A;  2CNG A;  1A5Y A;  4RI4 A;  3QCE A;  3F41 A;  1JLN A;  5M43 A;  2QDC A;  1LYV A;  1ONY A;  4ZI4 A;  1YPT A;  3MMJ A;  3RGO A;  2HC2 A;  3B7O A;  4B04 A;  1C86 A;  1WCH A;  4QBW A;  1QZ0 A;  2I6I A;  3CM3 A;  3RO1 A;  3ZM3 A;  1OEV A;  1OES A;  1ZCK A;  3ZV2 A;  2HVL A;  1G1G A;  2OC3 A;  3D1H A;  2CJZ A;  4RDD A;  4OHH A;  4KI9 A;  1LQF A;  2F6T A;  1PH0 A;  2AHS A;  4H34 A;  2VEY A;  2B4U A;  3S3H A;  3BM8 A;  3EMU A;  5KA7 A;  2I6M A;  2G59 A;  4GWF A;  4NYH A;  4HJP A;  2CNF A;  4GRZ A;  2HY3 A;  2Q05 A;  3I36 A;  5BUG A;  3O4S A;  1NZ7 A;  1C84 A;  2CM2 A;  3AWF A;  2H4K A;  4Z6B A;  4WU3 A;  1FQ1 A;  1Q6P A;  3F99 A;  3ZM0 A;  4GS0 A;  1C83 A;  2PA5 A;  2G6Z A;  4D3Q A; 
#chains in the Genus database with same CATH topology
 2FJM A;  3QKQ A;  1GFY A;  2M3V A;  4JBC A;  1I9T A;  1PTT A;  1ZC0 A;  3MVN A;  3H2X A;  3EAX A;  4OHI A;  2GJT A;  3UAG A;  2GCA A;  2AZR A;  3D42 A;  1XM2 A;  2CMC A;  3BRH A;  2F70 A;  1Q1M A;  2PQ5 A;  2HC1 A;  1PYN A;  2Y68 A;  1OET A;  1G4W R;  1JBW A;  3RGQ A;  2I3U A;  2QEP A;  1G7G A;  4CVM A;  3N2A A;  2VTD A;  2QBQ A;  4YR8 B;  3S4E A;  1O5Z A;  2F6V A;  2B49 A;  5IBS A;  2IMG A;  5BX1 A;  5I6V A;  2VEU A;  3I80 A;  1I57 A;  3F9B A;  2HNP A;  2UAG A;  2I6O A;  2NTA A;  2NZ6 A;  3CWE A;  4D3R A;  3EB1 A;  3A5K A;  4RH9 A;  1J4X A;  3V0I A;  2I4G A;  4RKK A;  1EEN A;  3QCM A;  2F6W A;  3A5J A;  2QCJ A;  1G4U S;  1L8G A;  1G7F A;  5A5F A;  5KA0 A;  2H04 A;  4H1O A;  2C7S A;  1X24 A;  4J51 A;  1XBO A;  3QCB A;  4GE6 A;  1OHD A;  2A3K A;  3S3K A;  4OHE A;  2CNI A;  2B4O A;  1P31 A;  3I7Z A;  2WTZ A;  2PT0 A;  3D1Q A;  5KA3 A;  2CMB A;  5AWX A;  2QDP A;  2F00 A;  2VEW A;  2WGP A;  1FGS A;  2HB1 A;  1PA1 A;  1BZJ A;  2HCM A;  3QCH A;  1C85 A;  2WJP A;  1OHE A;  2F6Y A;  3EZZ A;  4BUB A;  4JMK A;  3ZMQ A;  2GC6 A;  2Y66 A;  1YWF A;  4GFU A;  4CVL A;  3D44 A;  2PI7 A;  4HJQ A;  3U96 A;  5KA2 A;  3GXG A;  4IKC A;  1PA9 A;  2X5O A;  2QBS A;  3D1O A;  2JFH A;  2BGD A;  3V0J A;  1R6H A;  5K22 A;  1FPR A;  3ZM1 A;  5K23 A;  1MKP A;  2AM2 A;  3F9A A;  4GRY A;  1EEO A;  2BV5 A;  1T49 A;  3QKP A;  5KAD A;  1YN9 A;  5KA4 A;  2BIJ A;  2ESB A;  1NL9 A;  1XRI A;  1PTU A;  1SUG A;  1BZC A;  4OHL A;  4BPC A;  2NT2 A;  4C12 A;  4JNB A;  4ERC A;  2CNH A;  3QCI A;  2XPC A;  3EU0 A;  2FJN A;  1YZ4 A;  2JFF A;  2YDU A;  1U25 A;  2B4S A;  2CM8 A;  4NX8 A;  4QF5 A;  5K9V A;  1C87 A;  2Y96 A;  2GCB A;  4AZ1 A;  1G1F A;  4RH5 A;  2A8B A;  4NND A;  4R30 A;  2BZL A;  3LJ8 A;  3ZL8 A;  2DXP A;  1JBV A;  1P15 A;  2I5X A;  1GQY A;  4C13 A;  1YFO A;  3V0E A;  3ZMP A;  1KAV A;  3S3F A;  2J16 B;  3O3L A;  3BLU A;  4MBB A;  2OUD A;  1GG4 A;  5K24 A;  4NWF A;  4QDI A;  2ZN7 A;  1KAK A;  3SR9 A;  1BZH A;  4NWG A;  1GQQ A;  1Q6N A;  5IBM A;  1Q6M A;  4BJO A;  1FPZ A;  3HN7 A;  5HDE A;  2MBC A;  2CM3 A;  1Q6S A;  2JJD A;  2H4V A;  1I9S A;  4ZRT A;  1OEU A;  2Y1O A;  2VEX A;  3QCN A;  3PS5 A;  3NME A;  2NV5 A;  4DGX A;  4WTY A;  3QCK A;  1OHC A;  2F46 A;  1YTS A;  2F6Z A;  2VTE A;  1E8C A;  2RF6 A;  1D5R A;  1NO6 A;  5KAB A;  4Y14 A;  1M3G A;  3BLT A;  2B07 A;  1T48 A;  1ONZ A;  4PYH A;  1WAX A;  5GTJ A;  1PTY A;  5KA8 A;  3RZ2 A;  4R0T A;  3NRS A;  3OLR A;  5BZZ A;  2I6J A;  4PVG A;  3V0G A;  1EEH A;  2I4E A;  3PYZ A;  3QCF A;  2J16 A;  2NLK A;  2P4D A;  4ICZ A;  4ZIY A;  2Y2F A;  4R0S A;  1YGU A;  5J8R A;  3SME A;  2B3O A;  1OEO X;  3QCG A;  4WOH A;  2XJA A;  5LXQ B;  3F81 A;  2CFV A;  3GXH A;  5EHR A;  3S4O A;  1ZZW A;  4QUM A;  2B4P A;  2QCT A;  2CMA A;  4JMJ A;  3S3E A;  4DGP A;  2GWO A;  3QCL A;  2SHP A;  2H02 A;  2FH7 A;  3M4U A;  4OHD A;  2VOS A;  1C88 A;  3QCD A;  2CNE A;  2I3R A;  4D3P A;  4KYQ A;  2F71 A;  4Y2E A;  2R0B A;  3AWE A;  4QUN A;  2PBN A;  5KAA A;  2NT7 A;  1W7K A;  2OZ5 A;  4RI5 A;  2J17 A;  3V0D A;  3QCZ A;  5MMZ B;  4GFV A;  1JF7 A;  4QBE A;  5EHP A;  2JFG A;  2I1Y A;  2H03 A;  1Q6T A;  5KA1 A;  2I75 A;  4QAH A;  3V0F A;  2BGE A;  3ZM5 A;  1J6U A;  1WRM A;  2I6P A;  1YGR A;  2C46 A;  4TVV A;  3V0H A;  1ZCL A;  1NWE A;  5BZX A;  1NNY A;  2H4G A;  1QXK A;  4GE2 A;  1T4J A;  4ZN5 A;  2AM1 A;  4GE5 A;  2I4H A;  1PXH A;  2I42 A;  1XXP A;  3MOZ A;  1RXD A;  1YTW A;  2VEV A;  5A5E A;  2GP0 A;  2CM7 A;  5KA9 A;  2HNQ A;  4S0G A;  4I8N A;  4YAA A;  2ZMM A;  1GWZ A;  2QDM A;  3ZM2 A;  1XXV A;  1RPM A;  1Q6J A;  2P6X A;  4BUC A;  5KAC A;  2Q47 A;  1U24 A;  4KYR A;  3D9C A;  4HRF A;  1G1H A;  1ECV A;  1V3A A;  2QBP A;  1L8K A;  3OMH A;  1P3D A;  2VOR A;  3O4U A;  1E0D A;  2OOQ A;  1LAR A;  4WU2 A;  1YTN A;  3QCJ A;  1U26 A;  2E0T A;  3AWG A;  3O4T A;  5K25 A;  5K9W A;  2PSZ A;  3QCC A;  1NWL A;  2QBR A;  1AAX A;  1OEM X;  1VHR A;  4QAP A;  2F6F A;  1PTV A;  3O5X A;  3MOW A;  2HXP A;  3N0A A;  4RHG A;  2CNG A;  1A5Y A;  4RI4 A;  3QCE A;  4HV4 A;  3F41 A;  1JLN A;  5M43 A;  2QDC A;  1LYV A;  1ONY A;  4ZI4 A;  1W78 A;  1YPT A;  3MMJ A;  3RGO A;  2HC2 A;  3B7O A;  4B04 A;  4CVK A;  1C86 A;  1WCH A;  4QBW A;  1QZ0 A;  2I6I A;  3CM3 A;  3RO1 A;  3ZM3 A;  1OEV A;  1OES A;  1ZCK A;  3ZV2 A;  2HVL A;  1G1G A;  3LK7 A;  2OC3 A;  3D1H A;  2CJZ A;  4RDD A;  4OHH A;  4KI9 A;  1LQF A;  2F6T A;  1PH0 A;  2AHS A;  4H34 A;  2VEY A;  1UAG A;  2B4U A;  4UAG A;  3S3H A;  3BM8 A;  2GC5 A;  3EMU A;  5KA7 A;  2I6M A;  2G59 A;  4GWF A;  4NYH A;  4HJP A;  2CNF A;  4GRZ A;  2HY3 A;  2Q05 A;  3ZM6 A;  3I36 A;  5BUG A;  3O4S A;  1NZ7 A;  1C84 A;  2CM2 A;  3AWF A;  2H4K A;  4Z6B A;  4WU3 A;  1FQ1 A;  2UUP A;  1Q6P A;  2Y67 A;  3F99 A;  3ZM0 A;  2UUO A;  4GS0 A;  1C83 A;  2PA5 A;  2G6Z A;  4D3Q A; 
#chains in the Genus database with same CATH homology
 2FJM A;  3QKQ A;  1GFY A;  2M3V A;  4JBC A;  1I9T A;  1PTT A;  1ZC0 A;  3H2X A;  3EAX A;  4OHI A;  2GJT A;  2AZR A;  3D42 A;  1XM2 A;  2CMC A;  3BRH A;  2F70 A;  1Q1M A;  2PQ5 A;  2HC1 A;  1PYN A;  1OET A;  1G4W R;  3RGQ A;  2I3U A;  2QEP A;  1G7G A;  2QBQ A;  4YR8 B;  3S4E A;  2F6V A;  2B49 A;  5IBS A;  2IMG A;  5BX1 A;  5I6V A;  2VEU A;  3I80 A;  1I57 A;  3F9B A;  2HNP A;  2I6O A;  2NTA A;  2NZ6 A;  3CWE A;  4D3R A;  3EB1 A;  3A5K A;  4RH9 A;  1J4X A;  3V0I A;  2I4G A;  4RKK A;  1EEN A;  3QCM A;  2F6W A;  3A5J A;  2QCJ A;  1G4U S;  1L8G A;  1G7F A;  5KA0 A;  2H04 A;  4H1O A;  2C7S A;  1X24 A;  4J51 A;  1XBO A;  3QCB A;  4GE6 A;  1OHD A;  2A3K A;  3S3K A;  4OHE A;  2CNI A;  2B4O A;  3I7Z A;  2PT0 A;  3D1Q A;  5KA3 A;  2CMB A;  5AWX A;  2QDP A;  2VEW A;  2WGP A;  2HB1 A;  1PA1 A;  1BZJ A;  2HCM A;  3QCH A;  1C85 A;  1OHE A;  2F6Y A;  3EZZ A;  4JMK A;  3ZMQ A;  1YWF A;  4GFU A;  3D44 A;  2PI7 A;  4HJQ A;  3U96 A;  5KA2 A;  3GXG A;  4IKC A;  1PA9 A;  2QBS A;  3D1O A;  2BGD A;  3V0J A;  1R6H A;  5K22 A;  1FPR A;  3ZM1 A;  5K23 A;  1MKP A;  4GRY A;  3F9A A;  1EEO A;  2BV5 A;  1T49 A;  3QKP A;  5KAD A;  1YN9 A;  5KA4 A;  2BIJ A;  2ESB A;  1NL9 A;  1XRI A;  1PTU A;  1SUG A;  1BZC A;  4OHL A;  4BPC A;  2NT2 A;  4JNB A;  4ERC A;  2CNH A;  3QCI A;  3EU0 A;  2FJN A;  1YZ4 A;  2YDU A;  1U25 A;  2B4S A;  2CM8 A;  4NX8 A;  5K9V A;  1C87 A;  2Y96 A;  4AZ1 A;  1G1F A;  4RH5 A;  2A8B A;  4NND A;  4R30 A;  2BZL A;  3LJ8 A;  2DXP A;  1P15 A;  2I5X A;  1YFO A;  3V0E A;  3ZMP A;  1KAV A;  3S3F A;  2J16 B;  3O3L A;  3BLU A;  4MBB A;  2OUD A;  5K24 A;  4NWF A;  2ZN7 A;  1KAK A;  3SR9 A;  1BZH A;  4NWG A;  1Q6N A;  5IBM A;  1Q6M A;  4BJO A;  1FPZ A;  5HDE A;  2MBC A;  2CM3 A;  1Q6S A;  2JJD A;  2H4V A;  1I9S A;  4ZRT A;  1OEU A;  2VEX A;  3QCN A;  3PS5 A;  3NME A;  2NV5 A;  4DGX A;  4WTY A;  3QCK A;  1OHC A;  2F46 A;  1YTS A;  2F6Z A;  2RF6 A;  1D5R A;  1NO6 A;  5KAB A;  4Y14 A;  1M3G A;  3BLT A;  2B07 A;  1T48 A;  1ONZ A;  4PYH A;  1WAX A;  5GTJ A;  1PTY A;  5KA8 A;  3RZ2 A;  4R0T A;  3OLR A;  5BZZ A;  2I6J A;  4PVG A;  3V0G A;  2I4E A;  3QCF A;  2J16 A;  2NLK A;  2P4D A;  4ICZ A;  2Y2F A;  4R0S A;  1YGU A;  5J8R A;  3SME A;  2B3O A;  1OEO X;  3QCG A;  4WOH A;  5LXQ B;  3F81 A;  2CFV A;  3GXH A;  5EHR A;  3S4O A;  1ZZW A;  4QUM A;  2B4P A;  2QCT A;  2CMA A;  4JMJ A;  3S3E A;  4DGP A;  2GWO A;  3QCL A;  2SHP A;  2H02 A;  2FH7 A;  3M4U A;  4OHD A;  1C88 A;  3QCD A;  2CNE A;  2I3R A;  4D3P A;  4KYQ A;  2F71 A;  4Y2E A;  2R0B A;  3AWE A;  4QUN A;  2PBN A;  5KAA A;  2NT7 A;  2OZ5 A;  4RI5 A;  2J17 A;  3V0D A;  5MMZ B;  4GFV A;  1JF7 A;  4QBE A;  5EHP A;  2I1Y A;  2H03 A;  1Q6T A;  5KA1 A;  2I75 A;  4QAH A;  3V0F A;  2BGE A;  1WRM A;  2I6P A;  1YGR A;  2C46 A;  4TVV A;  3V0H A;  1ZCL A;  1NWE A;  5BZX A;  1NNY A;  2H4G A;  1QXK A;  4GE2 A;  1T4J A;  4ZN5 A;  4GE5 A;  2I4H A;  1PXH A;  2I42 A;  1XXP A;  3MOZ A;  1RXD A;  1YTW A;  2VEV A;  2GP0 A;  2CM7 A;  5KA9 A;  2HNQ A;  4S0G A;  4I8N A;  4YAA A;  2ZMM A;  1GWZ A;  2QDM A;  3ZM2 A;  1XXV A;  1RPM A;  1Q6J A;  2P6X A;  5KAC A;  2Q47 A;  1U24 A;  4KYR A;  3D9C A;  4HRF A;  1G1H A;  1ECV A;  1V3A A;  2QBP A;  1L8K A;  3OMH A;  3O4U A;  2OOQ A;  1LAR A;  4WU2 A;  1YTN A;  3QCJ A;  1U26 A;  2E0T A;  3AWG A;  3O4T A;  5K25 A;  5K9W A;  2PSZ A;  3QCC A;  1NWL A;  2QBR A;  1AAX A;  1OEM X;  1VHR A;  4QAP A;  2F6F A;  1PTV A;  3O5X A;  3MOW A;  2HXP A;  3N0A A;  4RHG A;  2CNG A;  1A5Y A;  4RI4 A;  3QCE A;  3F41 A;  1JLN A;  5M43 A;  2QDC A;  1LYV A;  1ONY A;  4ZI4 A;  1YPT A;  3MMJ A;  3RGO A;  2HC2 A;  3B7O A;  4B04 A;  1C86 A;  1WCH A;  4QBW A;  1QZ0 A;  2I6I A;  3CM3 A;  3RO1 A;  3ZM3 A;  1OEV A;  1OES A;  1ZCK A;  3ZV2 A;  2HVL A;  1G1G A;  2OC3 A;  3D1H A;  2CJZ A;  4RDD A;  4OHH A;  4KI9 A;  1LQF A;  2F6T A;  1PH0 A;  2AHS A;  4H34 A;  2VEY A;  2B4U A;  3S3H A;  3BM8 A;  3EMU A;  5KA7 A;  2I6M A;  2G59 A;  4GWF A;  4NYH A;  4HJP A;  2CNF A;  4GRZ A;  2HY3 A;  2Q05 A;  3I36 A;  5BUG A;  3O4S A;  1NZ7 A;  1C84 A;  2CM2 A;  3AWF A;  2H4K A;  4Z6B A;  4WU3 A;  1FQ1 A;  1Q6P A;  3F99 A;  3ZM0 A;  4GS0 A;  1C83 A;  2PA5 A;  2G6Z A;  4D3Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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