1Q1MA

A highly efficient approach to a selective and cell active ptp1b inhibitors
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
298
structure length
298
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein-tyrosine phosphatase, non-receptor type 1
total genus 107
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2003-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1q1mA00
4GS0A 1YN9A 5AWXA 4QUMA 4RI4A 1PTYA 1T49A 2CNHA 4WU2A 2FH7A 1G1FA 1Q6MA 2CM2A 2CMAA 3QCGA 2B07A 2H03A 2G6ZA 4RH9A 4Y14A 2H4GA 4WTYA 3I7ZA 4ZN5A 3ZM1A 2J16B 4GE5A 1G7GA 1Q1MA 2B4PA 4OHIA 2A3KA 3PS5A 4OHEA 1YTNA 2F70A 3ZV2A 1V3AA 2CM3A 2C46A 3BRHA 2BZLA 2NT7A 4JNBA 2MBCA 2PT0A 4ERCA 4JBCA 5KA4A 2F6YA 1YWFA 2VEWA 2B4SA 5KA8A 2NLKA 3ZM2A 1GWZA 2DXPA 3QCNA 4PYHA 4ICZA 2CNIA 1JLNA 5K23A 1RPMA 4RH5A 4D3PA 3ZM0A 2CFVA 3ZM3A 1YGUA 4RDDA 1YTWA 2YDUA 1T48A 5BUGA 3D1QA 3QKQA 5BX1A 2CJZA 2ESBA 2CNEA 5K9WA 5KAAA 3EB1A 2H4VA 1X24A 1XRIA 5EHRA 1XXVA 2I6MA 3I80A 3OMHA 1I9TA 3EZZA 3MOWA 4H34A 4NYHA 2J16A 4PVGA 1QXKA 1GFYA 3SMEA 3V0FA 2F46A 1JF7A 2Y2FA 4ZI4A 3RGOA 4D3RA 2ZN7A 4DGXA 3O4UA 4WU3A 2HY3A 2SHPA 4GE2A 4GWFA 2H04A 2I6OA 4NNDA 5KADA 2QBQA 4GRYA 5K25A 4Z6BA 3V0IA 2AZRA 2CMBA 4JMKA 3GXGA 2A8BA 3QCBA 2PSZA 3D44A 2AHSA 3H2XA 4KYRA 2BV5A 2P6XA 4IKCA 5KA2A 1VHRA 3D1HA 2H4KA 1ECVA 2NZ6A 1QZ0A 2VEUA 3V0DA 5LXQB 1J4XA 1G1HA 2QBPA 4TVVA 3CWEA 4YAAA 4HRFA 1Q6SA 2PI7A 2I5XA 2I3RA 2OOQA 1XBOA 4QBWA 5KA7A 4NWFA 1KAVA 1PTVA 1C88A 2I4HA 1G7FA 3MOZA 1NNYA 1NWLA 5KA0A 2I1YA 2OUDA 2GWOA 4OHLA 2FJMA 1RXDA 2CMCA 1C87A 2QCJA 1NZ7A 2I6IA 3QCFA 3O4TA 1YTSA 5MMZB 1PTUA 1FPZA 1SUGA 2CNFA 2F71A 5K9VA 5M43A 1OETA 1FPRA 3I36A 3QCJA 1OEMX 1G4US 2QBRA 1NWEA 5IBSA 4WOHA 1C86A 4Y2EA 3QCIA 1Q6PA 3QCEA 2VEVA 2I6JA 3A5KA 3SR9A 4S0GA 2QBSA 1YPTA 2BGDA 2PBNA 4R0SA 5HDEA 4GRZA 2QEPA 4QBEA 3CM3A 3BLUA 1L8GA 2I75A 2CNGA 2ZMMA 1WAXA 5K24A 5GTJA 1PA9A 3AWGA 2FJNA 2E0TA 4QAHA 2PQ5A 3AWEA 3QCDA 4RI5A 2F6TA 3LJ8A 1P15A 1T4JA 5KA9A 1BZHA 5KACA 3O4SA 2VEYA 2HNQA 4D3QA 2I6PA 4BPCA 3S4EA 1OHDA 3QCHA 3D1OA 2QDMA 4HJPA 1U25A 1BZJA 3BLTA 2HVLA 2QDCA 2B49A 1LARA 1ZCKA 2I4EA 1ZZWA 2J17A 2P4DA 4QAPA 1EEOA 1WCHA 1G1GA 2CM7A 5EHPA 4J51A 5IBMA 1M3GA 4HJQA 1I57A 1YFOA 2G59A 2GJTA 1Q6TA 3F99A 1G4WR 1ONYA 3EMUA 1YZ4A 2I42A 3S3KA 2HB1A 4AZ1A 2RF6A 2JJDA 1C83A 1PA1A 1I9SA 1U26A 1U24A 1PYNA 2HC1A 4R0TA 5BZXA 4DGPA 3OLRA 1Q6NA 4KYQA 3S3EA 1WRMA 4I8NA 1R6HA 2HXPA 1OEVA 2Q05A 1Q6JA 1YGRA 1EENA 4BJOA 3RZ2A 1L8KA 3QCKA 2I3UA 2VEXA 1C84A 2IMGA 3QCMA 3F9BA 5I6VA 1OESA 4NWGA 3V0GA 3V0HA 3EU0A 2F6WA 2HNPA 4GE6A 4R30A 1PTTA 2F6FA 1A5YA 3NMEA 3EAXA 3MMJA 3V0EA 2CM8A 3F41A 2NT2A 4KI9A 2QCTA 1OEUA 4JMJA 2WGPA 1LQFA 3V0JA 3M4UA 5KABA 4YR8B 1LYVA 1OHEA 3BM8A 1PH0A 1XM2A 5KA1A 2BIJA 3O5XA 4QUNA 2OC3A 1C85A 2Y96A 2GP0A 2BGEA 2R0BA 4H1OA 4GFVA 2HC2A 1ZC0A 1NO6A 4B04A 2Q47A 3AWFA 1PXHA 3ZMPA 2HCMA 3F81A 4MBBA 5K22A 3B7OA 2B4UA 3S4OA 1ZCLA 5KA3A 2OZ5A 3GXHA 3D42A 1OHCA 2I4GA 1OEOX 1KAKA 2F6ZA 4RHGA 3O3LA 2F6VA 3S3FA 2QDPA 3QCLA 3U96A 4RKKA 2B3OA 4ZRTA 5BZZA 2NV5A 3RGQA 3RO1A 2C7SA 2NTAA 1NL9A 1XXPA 1FQ1A 3A5JA 1AAXA 4NX8A 2H02A 3QKPA 3ZMQA 1D5RA 4OHDA 2M3VA 4GFUA 1ONZA 1MKPA 4OHHA 3D9CA 3S3HA 2B4OA 3QCCA 1BZCA 3F9AA 3N0AA 5J8RA 2PA5A
chains in the Genus database with same CATH superfamily
4GS0A 1YN9A 5AWXA 4C13A 4QUMA 4RI4A 1PTYA 1T49A 2CNHA 4WU2A 2FH7A 1G1FA 1Q6MA 2CM2A 2CMAA 2XPCA 3QCGA 3QCZA 2B07A 2H03A 2G6ZA 4RH9A 4Y14A 2H4GA 4WTYA 3I7ZA 4ZN5A 1UAGA 3ZM1A 2GCAA 2J16B 4GE5A 1G7GA 1Q1MA 2B4PA 4OHIA 2A3KA 3PS5A 4OHEA 1YTNA 2F70A 3ZV2A 1V3AA 2CM3A 2C46A 3BRHA 2BZLA 2NT7A 4JNBA 2GC6A 2MBCA 2PT0A 4ERCA 5A5FA 4JBCA 5KA4A 2F6YA 1YWFA 2VEWA 2B4SA 5KA8A 2NLKA 3ZM2A 1GWZA 2DXPA 3QCNA 4PYHA 4ICZA 2CNIA 1JLNA 5K23A 1RPMA 4RH5A 4D3PA 3ZM0A 2CFVA 3ZM3A 1YGUA 4RDDA 3HN7A 1YTWA 2YDUA 1T48A 5BUGA 3D1QA 3QKQA 5BX1A 2CJZA 1E0DA 2ESBA 2CNEA 5K9WA 5KAAA 3EB1A 2H4VA 1X24A 1XRIA 5EHRA 1XXVA 2I6MA 3I80A 3OMHA 1I9TA 3EZZA 3LK7A 3MOWA 4H34A 4NYHA 2J16A 4PVGA 1QXKA 1GFYA 3SMEA 3V0FA 2F46A 1JF7A 2Y2FA 4ZI4A 3RGOA 4D3RA 2ZN7A 4DGXA 3O4UA 4WU3A 2HY3A 2SHPA 4GE2A 4GWFA 4QF5A 2H04A 2I6OA 4NNDA 5KADA 2QBQA 4GRYA 5K25A 4Z6BA 3V0IA 2AZRA 2CMBA 4JMKA 3GXGA 3ZM6A 2A8BA 3QCBA 2PSZA 3D44A 2AHSA 3H2XA 4KYRA 2BV5A 2P6XA 1GQQA 4IKCA 5KA2A 1VHRA 3D1HA 2H4KA 1ECVA 1JBWA 2NZ6A 1QZ0A 2VEUA 3V0DA 5LXQB 1J4XA 1G1HA 2QBPA 4TVVA 2Y68A 3CWEA 4YAAA 4HRFA 1Q6SA 2PI7A 4UAGA 2I5XA 2VOSA 2I3RA 2OOQA 3UAGA 1XBOA 4QBWA 5KA7A 4NWFA 1KAVA 1PTVA 1C88A 1W7KA 1J6UA 2I4HA 1G7FA 3MOZA 1NNYA 1NWLA 5KA0A 2I1YA 2OUDA 2GWOA 2XJAA 4OHLA 2FJMA 2JFFA 1RXDA 2CMCA 1C87A 2QCJA 1NZ7A 2I6IA 3QCFA 3O4TA 1YTSA 5MMZB 1PTUA 2JFGA 1FPZA 1SUGA 2CNFA 2F71A 5K9VA 5M43A 1OETA 1FPRA 1GQYA 3I36A 3QCJA 1OEMX 1G4US 2QBRA 1NWEA 5IBSA 4WOHA 1C86A 2Y67A 4Y2EA 4BUBA 3QCIA 1Q6PA 3QCEA 2VEVA 2I6JA 3A5KA 3SR9A 4S0GA 2QBSA 1YPTA 2BGDA 2PBNA 4R0SA 5HDEA 4GRZA 2QEPA 1E8CA 4QBEA 3CM3A 3BLUA 2GC5A 4CVLA 1L8GA 2I75A 2CNGA 2ZMMA 1WAXA 5K24A 5GTJA 1PA9A 3AWGA 2FJNA 2Y66A 2E0TA 4QAHA 2PQ5A 3AWEA 3QCDA 3ZL8A 4RI5A 2X5OA 2F6TA 3LJ8A 1P15A 4QDIA 1T4JA 5KA9A 1BZHA 5KACA 3O4SA 2VEYA 2HNQA 4D3QA 2JFHA 2I6PA 4BPCA 3S4EA 1OHDA 3QCHA 3D1OA 2QDMA 4HJPA 1U25A 1BZJA 3BLTA 2HVLA 2QDCA 2B49A 1LARA 1ZCKA 2I4EA 4HV4A 1ZZWA 2J17A 2P4DA 4QAPA 1EEOA 1WCHA 1G1GA 2CM7A 3ZM5A 5EHPA 4J51A 5IBMA 1M3GA 4HJQA 1I57A 1YFOA 2G59A 2GJTA 1Q6TA 3F99A 1G4WR 1W78A 1ONYA 1EEHA 3EMUA 1YZ4A 2I42A 3S3KA 2HB1A 4AZ1A 2RF6A 2JJDA 1C83A 1PA1A 2UUOA 3MVNA 4CVKA 1I9SA 1U26A 1U24A 1PYNA 2AM2A 2HC1A 4R0TA 5BZXA 4DGPA 3OLRA 2VTEA 1Q6NA 4KYQA 3S3EA 1WRMA 4I8NA 1R6HA 2HXPA 1OEVA 2Q05A 1Q6JA 1YGRA 2F00A 1EENA 2VORA 4BJOA 3RZ2A 1L8KA 2AM1A 3QCKA 2I3UA 2VEXA 1C84A 2UUPA 2IMGA 3QCMA 3F9BA 5I6VA 1OESA 4CVMA 2GCBA 4NWGA 3V0GA 3V0HA 2F6WA 3EU0A 2HNPA 4GE6A 4R30A 3N2AA 1PTTA 2F6FA 1A5YA 3NMEA 3EAXA 3MMJA 3V0EA 2CM8A 3PYZA 3F41A 2NT2A 4KI9A 2QCTA 1OEUA 4JMJA 2WGPA 1P3DA 1LQFA 4ZIYA 3V0JA 3M4UA 5KABA 4YR8B 2UAGA 1LYVA 1OHEA 3BM8A 1PH0A 1XM2A 3NRSA 5KA1A 2BIJA 3O5XA 4QUNA 2OC3A 4BUCA 1C85A 2Y96A 2GP0A 2BGEA 2R0BA 4H1OA 4GFVA 2HC2A 1ZC0A 1NO6A 4B04A 2Q47A 3AWFA 1PXHA 3ZMPA 1O5ZA 2HCMA 3F81A 4MBBA 5K22A 3B7OA 2B4UA 3S4OA 1ZCLA 5KA3A 2OZ5A 3GXHA 3D42A 1OHCA 2I4GA 1OEOX 1KAKA 2F6ZA 2WJPA 4RHGA 3O3LA 2F6VA 3S3FA 2QDPA 3QCLA 3U96A 4C12A 4RKKA 2B3OA 4ZRTA 5BZZA 2NV5A 2VTDA 3RGQA 3RO1A 2Y1OA 2C7SA 2NTAA 1NL9A 2WTZA 1XXPA 1FQ1A 3A5JA 1AAXA 4NX8A 2H02A 1GG4A 3QKPA 3ZMQA 1D5RA 1P31A 1FGSA 4OHDA 2M3VA 4GFUA 1ONZA 5A5EA 1MKPA 4OHHA 3D9CA 3S3HA 2B4OA 3QCCA 1BZCA 3F9AA 3N0AA 5J8RA 1JBVA 2PA5A
chains in the Genus database with same CATH topology
4GS0A 1YN9A 5AWXA 4QUMA 4RI4A 1PTYA 1T49A 2CNHA 4WU2A 2FH7A 1G1FA 1Q6MA 2CM2A 2CMAA 3QCGA 2B07A 2H03A 2G6ZA 4RH9A 4Y14A 2H4GA 4WTYA 3I7ZA 4ZN5A 3ZM1A 2J16B 4GE5A 1G7GA 1Q1MA 2B4PA 4OHIA 2A3KA 3PS5A 4OHEA 1YTNA 2F70A 3ZV2A 1V3AA 2CM3A 2C46A 3BRHA 2BZLA 2NT7A 4JNBA 2MBCA 2PT0A 4ERCA 4JBCA 5KA4A 2F6YA 1YWFA 2VEWA 2B4SA 5KA8A 2NLKA 3ZM2A 1GWZA 2DXPA 3QCNA 4PYHA 4ICZA 2CNIA 1JLNA 5K23A 1RPMA 4RH5A 4D3PA 3ZM0A 2CFVA 3ZM3A 1YGUA 4RDDA 1YTWA 2YDUA 1T48A 5BUGA 3D1QA 3QKQA 5BX1A 2CJZA 2ESBA 2CNEA 5K9WA 5KAAA 3EB1A 2H4VA 1X24A 1XRIA 5EHRA 1XXVA 2I6MA 3I80A 3OMHA 1I9TA 3EZZA 3MOWA 4H34A 4NYHA 2J16A 4PVGA 1QXKA 1GFYA 3SMEA 3V0FA 2F46A 1JF7A 2Y2FA 4ZI4A 3RGOA 4D3RA 2ZN7A 4DGXA 3O4UA 4WU3A 2HY3A 2SHPA 4GE2A 4GWFA 2H04A 2I6OA 4NNDA 5KADA 2QBQA 4GRYA 5K25A 4Z6BA 3V0IA 2AZRA 2CMBA 4JMKA 3GXGA 2A8BA 3QCBA 2PSZA 3D44A 2AHSA 3H2XA 4KYRA 2BV5A 2P6XA 4IKCA 5KA2A 1VHRA 3D1HA 2H4KA 1ECVA 2NZ6A 1QZ0A 2VEUA 3V0DA 5LXQB 1J4XA 1G1HA 2QBPA 4TVVA 3CWEA 4YAAA 4HRFA 1Q6SA 2PI7A 2I5XA 2I3RA 2OOQA 1XBOA 4QBWA 5KA7A 4NWFA 1KAVA 1PTVA 1C88A 2I4HA 1G7FA 3MOZA 1NNYA 1NWLA 5KA0A 2I1YA 2OUDA 2GWOA 4OHLA 2FJMA 1RXDA 2CMCA 1C87A 2QCJA 1NZ7A 2I6IA 3QCFA 3O4TA 1YTSA 5MMZB 1PTUA 1FPZA 1SUGA 2CNFA 2F71A 5K9VA 5M43A 1OETA 1FPRA 3I36A 3QCJA 1OEMX 1G4US 2QBRA 1NWEA 5IBSA 4WOHA 1C86A 4Y2EA 3QCIA 1Q6PA 3QCEA 2VEVA 2I6JA 3A5KA 3SR9A 4S0GA 2QBSA 1YPTA 2BGDA 2PBNA 4R0SA 5HDEA 4GRZA 2QEPA 4QBEA 3CM3A 3BLUA 1L8GA 2I75A 2CNGA 2ZMMA 1WAXA 5K24A 5GTJA 1PA9A 3AWGA 2FJNA 2E0TA 4QAHA 2PQ5A 3AWEA 3QCDA 4RI5A 2F6TA 3LJ8A 1P15A 1T4JA 5KA9A 1BZHA 5KACA 3O4SA 2VEYA 2HNQA 4D3QA 2I6PA 4BPCA 3S4EA 1OHDA 3QCHA 3D1OA 2QDMA 4HJPA 1U25A 1BZJA 3BLTA 2HVLA 2QDCA 2B49A 1LARA 1ZCKA 2I4EA 1ZZWA 2J17A 2P4DA 4QAPA 1EEOA 1WCHA 1G1GA 2CM7A 5EHPA 4J51A 5IBMA 1M3GA 4HJQA 1I57A 1YFOA 2G59A 2GJTA 1Q6TA 3F99A 1G4WR 1ONYA 3EMUA 1YZ4A 2I42A 3S3KA 2HB1A 4AZ1A 2RF6A 2JJDA 1C83A 1PA1A 1I9SA 1U26A 1U24A 1PYNA 2HC1A 4R0TA 5BZXA 4DGPA 3OLRA 1Q6NA 4KYQA 3S3EA 1WRMA 4I8NA 1R6HA 2HXPA 1OEVA 2Q05A 1Q6JA 1YGRA 1EENA 4BJOA 3RZ2A 1L8KA 3QCKA 2I3UA 2VEXA 1C84A 2IMGA 3QCMA 3F9BA 5I6VA 1OESA 4NWGA 3V0GA 3V0HA 3EU0A 2F6WA 2HNPA 4GE6A 4R30A 1PTTA 2F6FA 1A5YA 3NMEA 3EAXA 3MMJA 3V0EA 2CM8A 3F41A 2NT2A 4KI9A 2QCTA 1OEUA 4JMJA 2WGPA 1LQFA 3V0JA 3M4UA 5KABA 4YR8B 1LYVA 1OHEA 3BM8A 1PH0A 1XM2A 5KA1A 2BIJA 3O5XA 4QUNA 2OC3A 1C85A 2Y96A 2GP0A 2BGEA 2R0BA 4H1OA 4GFVA 2HC2A 1ZC0A 1NO6A 4B04A 2Q47A 3AWFA 1PXHA 3ZMPA 2HCMA 3F81A 4MBBA 5K22A 3B7OA 2B4UA 3S4OA 1ZCLA 5KA3A 2OZ5A 3GXHA 3D42A 1OHCA 2I4GA 1OEOX 1KAKA 2F6ZA 4RHGA 3O3LA 2F6VA 3S3FA 2QDPA 3QCLA 3U96A 4RKKA 2B3OA 4ZRTA 5BZZA 2NV5A 3RGQA 3RO1A 2C7SA 2NTAA 1NL9A 1XXPA 1FQ1A 3A5JA 1AAXA 4NX8A 2H02A 3QKPA 3ZMQA 1D5RA 4OHDA 2M3VA 4GFUA 1ONZA 1MKPA 4OHHA 3D9CA 3S3HA 2B4OA 3QCCA 1BZCA 3F9AA 3N0AA 5J8RA 2PA5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GS0 A;  1YN9 A;  5AWX A;  4QUM A;  4RI4 A;  1PTY A;  1T49 A;  2CNH A;  4WU2 A;  2FH7 A;  1G1F A;  1Q6M A;  2CM2 A;  2CMA A;  3QCG A;  2B07 A;  2H03 A;  2G6Z A;  4RH9 A;  4Y14 A;  2H4G A;  4WTY A;  3I7Z A;  4ZN5 A;  3ZM1 A;  2J16 B;  4GE5 A;  1G7G A;  1Q1M A;  2B4P A;  4OHI A;  2A3K A;  3PS5 A;  4OHE A;  1YTN A;  2F70 A;  3ZV2 A;  1V3A A;  2CM3 A;  2C46 A;  3BRH A;  2BZL A;  2NT7 A;  4JNB A;  2MBC A;  2PT0 A;  4ERC A;  4JBC A;  5KA4 A;  2F6Y A;  1YWF A;  2VEW A;  2B4S A;  5KA8 A;  2NLK A;  3ZM2 A;  1GWZ A;  2DXP A;  3QCN A;  4PYH A;  4ICZ A;  2CNI A;  1JLN A;  5K23 A;  1RPM A;  4RH5 A;  4D3P A;  3ZM0 A;  2CFV A;  3ZM3 A;  1YGU A;  4RDD A;  1YTW A;  2YDU A;  1T48 A;  5BUG A;  3D1Q A;  3QKQ A;  5BX1 A;  2CJZ A;  2ESB A;  2CNE A;  5K9W A;  5KAA A;  3EB1 A;  2H4V A;  1X24 A;  1XRI A;  5EHR A;  1XXV A;  2I6M A;  3I80 A;  3OMH A;  1I9T A;  3EZZ A;  3MOW A;  4H34 A;  4NYH A;  2J16 A;  4PVG A;  1QXK A;  1GFY A;  3SME A;  3V0F A;  2F46 A;  1JF7 A;  2Y2F A;  4ZI4 A;  3RGO A;  4D3R A;  2ZN7 A;  4DGX A;  3O4U A;  4WU3 A;  2HY3 A;  2SHP A;  4GE2 A;  4GWF A;  2H04 A;  2I6O A;  4NND A;  5KAD A;  2QBQ A;  4GRY A;  5K25 A;  4Z6B A;  3V0I A;  2AZR A;  2CMB A;  4JMK A;  3GXG A;  2A8B A;  3QCB A;  2PSZ A;  3D44 A;  2AHS A;  3H2X A;  4KYR A;  2BV5 A;  2P6X A;  4IKC A;  5KA2 A;  1VHR A;  3D1H A;  2H4K A;  1ECV A;  2NZ6 A;  1QZ0 A;  2VEU A;  3V0D A;  5LXQ B;  1J4X A;  1G1H A;  2QBP A;  4TVV A;  3CWE A;  4YAA A;  4HRF A;  1Q6S A;  2PI7 A;  2I5X A;  2I3R A;  2OOQ A;  1XBO A;  4QBW A;  5KA7 A;  4NWF A;  1KAV A;  1PTV A;  1C88 A;  2I4H A;  1G7F A;  3MOZ A;  1NNY A;  1NWL A;  5KA0 A;  2I1Y A;  2OUD A;  2GWO A;  4OHL A;  2FJM A;  1RXD A;  2CMC A;  1C87 A;  2QCJ A;  1NZ7 A;  2I6I A;  3QCF A;  3O4T A;  1YTS A;  5MMZ B;  1PTU A;  1FPZ A;  1SUG A;  2CNF A;  2F71 A;  5K9V A;  5M43 A;  1OET A;  1FPR A;  3I36 A;  3QCJ A;  1OEM X;  1G4U S;  2QBR A;  1NWE A;  5IBS A;  4WOH A;  1C86 A;  4Y2E A;  3QCI A;  1Q6P A;  3QCE A;  2VEV A;  2I6J A;  3A5K A;  3SR9 A;  4S0G A;  2QBS A;  1YPT A;  2BGD A;  2PBN A;  4R0S A;  5HDE A;  4GRZ A;  2QEP A;  4QBE A;  3CM3 A;  3BLU A;  1L8G A;  2I75 A;  2CNG A;  2ZMM A;  1WAX A;  5K24 A;  5GTJ A;  1PA9 A;  3AWG A;  2FJN A;  2E0T A;  4QAH A;  2PQ5 A;  3AWE A;  3QCD A;  4RI5 A;  2F6T A;  3LJ8 A;  1P15 A;  1T4J A;  5KA9 A;  1BZH A;  5KAC A;  3O4S A;  2VEY A;  2HNQ A;  4D3Q A;  2I6P A;  4BPC A;  3S4E A;  1OHD A;  3QCH A;  3D1O A;  2QDM A;  4HJP A;  1U25 A;  1BZJ A;  3BLT A;  2HVL A;  2QDC A;  2B49 A;  1LAR A;  1ZCK A;  2I4E A;  1ZZW A;  2J17 A;  2P4D A;  4QAP A;  1EEO A;  1WCH A;  1G1G A;  2CM7 A;  5EHP A;  4J51 A;  5IBM A;  1M3G A;  4HJQ A;  1I57 A;  1YFO A;  2G59 A;  2GJT A;  1Q6T A;  3F99 A;  1G4W R;  1ONY A;  3EMU A;  1YZ4 A;  2I42 A;  3S3K A;  2HB1 A;  4AZ1 A;  2RF6 A;  2JJD A;  1C83 A;  1PA1 A;  1I9S A;  1U26 A;  1U24 A;  1PYN A;  2HC1 A;  4R0T A;  5BZX A;  4DGP A;  3OLR A;  1Q6N A;  4KYQ A;  3S3E A;  1WRM A;  4I8N A;  1R6H A;  2HXP A;  1OEV A;  2Q05 A;  1Q6J A;  1YGR A;  1EEN A;  4BJO A;  3RZ2 A;  1L8K A;  3QCK A;  2I3U A;  2VEX A;  1C84 A;  2IMG A;  3QCM A;  3F9B A;  5I6V A;  1OES A;  4NWG A;  3V0G A;  3V0H A;  3EU0 A;  2F6W A;  2HNP A;  4GE6 A;  4R30 A;  1PTT A;  2F6F A;  1A5Y A;  3NME A;  3EAX A;  3MMJ A;  3V0E A;  2CM8 A;  3F41 A;  2NT2 A;  4KI9 A;  2QCT A;  1OEU A;  4JMJ A;  2WGP A;  1LQF A;  3V0J A;  3M4U A;  5KAB A;  4YR8 B;  1LYV A;  1OHE A;  3BM8 A;  1PH0 A;  1XM2 A;  5KA1 A;  2BIJ A;  3O5X A;  4QUN A;  2OC3 A;  1C85 A;  2Y96 A;  2GP0 A;  2BGE A;  2R0B A;  4H1O A;  4GFV A;  2HC2 A;  1ZC0 A;  1NO6 A;  4B04 A;  2Q47 A;  3AWF A;  1PXH A;  3ZMP A;  2HCM A;  3F81 A;  4MBB A;  5K22 A;  3B7O A;  2B4U A;  3S4O A;  1ZCL A;  5KA3 A;  2OZ5 A;  3GXH A;  3D42 A;  1OHC A;  2I4G A;  1OEO X;  1KAK A;  2F6Z A;  4RHG A;  3O3L A;  2F6V A;  3S3F A;  2QDP A;  3QCL A;  3U96 A;  4RKK A;  2B3O A;  4ZRT A;  5BZZ A;  2NV5 A;  3RGQ A;  3RO1 A;  2C7S A;  2NTA A;  1NL9 A;  1XXP A;  1FQ1 A;  3A5J A;  1AAX A;  4NX8 A;  2H02 A;  3QKP A;  3ZMQ A;  1D5R A;  4OHD A;  2M3V A;  4GFU A;  1ONZ A;  1MKP A;  4OHH A;  3D9C A;  3S3H A;  2B4O A;  3QCC A;  1BZC A;  3F9A A;  3N0A A;  5J8R A;  2PA5 A; 
#chains in the Genus database with same CATH topology
 4GS0 A;  1YN9 A;  5AWX A;  4C13 A;  4QUM A;  4RI4 A;  1PTY A;  1T49 A;  2CNH A;  4WU2 A;  2FH7 A;  1G1F A;  1Q6M A;  2CM2 A;  2CMA A;  2XPC A;  3QCG A;  3QCZ A;  2B07 A;  2H03 A;  2G6Z A;  4RH9 A;  4Y14 A;  2H4G A;  4WTY A;  3I7Z A;  4ZN5 A;  1UAG A;  3ZM1 A;  2GCA A;  2J16 B;  4GE5 A;  1G7G A;  1Q1M A;  2B4P A;  4OHI A;  2A3K A;  3PS5 A;  4OHE A;  1YTN A;  2F70 A;  3ZV2 A;  1V3A A;  2CM3 A;  2C46 A;  3BRH A;  2BZL A;  2NT7 A;  4JNB A;  2GC6 A;  2MBC A;  2PT0 A;  4ERC A;  5A5F A;  4JBC A;  5KA4 A;  2F6Y A;  1YWF A;  2VEW A;  2B4S A;  5KA8 A;  2NLK A;  3ZM2 A;  1GWZ A;  2DXP A;  3QCN A;  4PYH A;  4ICZ A;  2CNI A;  1JLN A;  5K23 A;  1RPM A;  4RH5 A;  4D3P A;  3ZM0 A;  2CFV A;  3ZM3 A;  1YGU A;  4RDD A;  3HN7 A;  1YTW A;  2YDU A;  1T48 A;  5BUG A;  3D1Q A;  3QKQ A;  5BX1 A;  2CJZ A;  1E0D A;  2ESB A;  2CNE A;  5K9W A;  5KAA A;  3EB1 A;  2H4V A;  1X24 A;  1XRI A;  5EHR A;  1XXV A;  2I6M A;  3I80 A;  3OMH A;  1I9T A;  3EZZ A;  3LK7 A;  3MOW A;  4H34 A;  4NYH A;  2J16 A;  4PVG A;  1QXK A;  1GFY A;  3SME A;  3V0F A;  2F46 A;  1JF7 A;  2Y2F A;  4ZI4 A;  3RGO A;  4D3R A;  2ZN7 A;  4DGX A;  3O4U A;  4WU3 A;  2HY3 A;  2SHP A;  4GE2 A;  4GWF A;  4QF5 A;  2H04 A;  2I6O A;  4NND A;  5KAD A;  2QBQ A;  4GRY A;  5K25 A;  4Z6B A;  3V0I A;  2AZR A;  2CMB A;  4JMK A;  3GXG A;  3ZM6 A;  2A8B A;  3QCB A;  2PSZ A;  3D44 A;  2AHS A;  3H2X A;  4KYR A;  2BV5 A;  2P6X A;  1GQQ A;  4IKC A;  5KA2 A;  1VHR A;  3D1H A;  2H4K A;  1ECV A;  1JBW A;  2NZ6 A;  1QZ0 A;  2VEU A;  3V0D A;  5LXQ B;  1J4X A;  1G1H A;  2QBP A;  4TVV A;  2Y68 A;  3CWE A;  4YAA A;  4HRF A;  1Q6S A;  2PI7 A;  4UAG A;  2I5X A;  2VOS A;  2I3R A;  2OOQ A;  3UAG A;  1XBO A;  4QBW A;  5KA7 A;  4NWF A;  1KAV A;  1PTV A;  1C88 A;  1W7K A;  1J6U A;  2I4H A;  1G7F A;  3MOZ A;  1NNY A;  1NWL A;  5KA0 A;  2I1Y A;  2OUD A;  2GWO A;  2XJA A;  4OHL A;  2FJM A;  2JFF A;  1RXD A;  2CMC A;  1C87 A;  2QCJ A;  1NZ7 A;  2I6I A;  3QCF A;  3O4T A;  1YTS A;  5MMZ B;  1PTU A;  2JFG A;  1FPZ A;  1SUG A;  2CNF A;  2F71 A;  5K9V A;  5M43 A;  1OET A;  1FPR A;  1GQY A;  3I36 A;  3QCJ A;  1OEM X;  1G4U S;  2QBR A;  1NWE A;  5IBS A;  4WOH A;  1C86 A;  2Y67 A;  4Y2E A;  4BUB A;  3QCI A;  1Q6P A;  3QCE A;  2VEV A;  2I6J A;  3A5K A;  3SR9 A;  4S0G A;  2QBS A;  1YPT A;  2BGD A;  2PBN A;  4R0S A;  5HDE A;  4GRZ A;  2QEP A;  1E8C A;  4QBE A;  3CM3 A;  3BLU A;  2GC5 A;  4CVL A;  1L8G A;  2I75 A;  2CNG A;  2ZMM A;  1WAX A;  5K24 A;  5GTJ A;  1PA9 A;  3AWG A;  2FJN A;  2Y66 A;  2E0T A;  4QAH A;  2PQ5 A;  3AWE A;  3QCD A;  3ZL8 A;  4RI5 A;  2X5O A;  2F6T A;  3LJ8 A;  1P15 A;  4QDI A;  1T4J A;  5KA9 A;  1BZH A;  5KAC A;  3O4S A;  2VEY A;  2HNQ A;  4D3Q A;  2JFH A;  2I6P A;  4BPC A;  3S4E A;  1OHD A;  3QCH A;  3D1O A;  2QDM A;  4HJP A;  1U25 A;  1BZJ A;  3BLT A;  2HVL A;  2QDC A;  2B49 A;  1LAR A;  1ZCK A;  2I4E A;  4HV4 A;  1ZZW A;  2J17 A;  2P4D A;  4QAP A;  1EEO A;  1WCH A;  1G1G A;  2CM7 A;  3ZM5 A;  5EHP A;  4J51 A;  5IBM A;  1M3G A;  4HJQ A;  1I57 A;  1YFO A;  2G59 A;  2GJT A;  1Q6T A;  3F99 A;  1G4W R;  1W78 A;  1ONY A;  1EEH A;  3EMU A;  1YZ4 A;  2I42 A;  3S3K A;  2HB1 A;  4AZ1 A;  2RF6 A;  2JJD A;  1C83 A;  1PA1 A;  2UUO A;  3MVN A;  4CVK A;  1I9S A;  1U26 A;  1U24 A;  1PYN A;  2AM2 A;  2HC1 A;  4R0T A;  5BZX A;  4DGP A;  3OLR A;  2VTE A;  1Q6N A;  4KYQ A;  3S3E A;  1WRM A;  4I8N A;  1R6H A;  2HXP A;  1OEV A;  2Q05 A;  1Q6J A;  1YGR A;  2F00 A;  1EEN A;  2VOR A;  4BJO A;  3RZ2 A;  1L8K A;  2AM1 A;  3QCK A;  2I3U A;  2VEX A;  1C84 A;  2UUP A;  2IMG A;  3QCM A;  3F9B A;  5I6V A;  1OES A;  4CVM A;  2GCB A;  4NWG A;  3V0G A;  3V0H A;  2F6W A;  3EU0 A;  2HNP A;  4GE6 A;  4R30 A;  3N2A A;  1PTT A;  2F6F A;  1A5Y A;  3NME A;  3EAX A;  3MMJ A;  3V0E A;  2CM8 A;  3PYZ A;  3F41 A;  2NT2 A;  4KI9 A;  2QCT A;  1OEU A;  4JMJ A;  2WGP A;  1P3D A;  1LQF A;  4ZIY A;  3V0J A;  3M4U A;  5KAB A;  4YR8 B;  2UAG A;  1LYV A;  1OHE A;  3BM8 A;  1PH0 A;  1XM2 A;  3NRS A;  5KA1 A;  2BIJ A;  3O5X A;  4QUN A;  2OC3 A;  4BUC A;  1C85 A;  2Y96 A;  2GP0 A;  2BGE A;  2R0B A;  4H1O A;  4GFV A;  2HC2 A;  1ZC0 A;  1NO6 A;  4B04 A;  2Q47 A;  3AWF A;  1PXH A;  3ZMP A;  1O5Z A;  2HCM A;  3F81 A;  4MBB A;  5K22 A;  3B7O A;  2B4U A;  3S4O A;  1ZCL A;  5KA3 A;  2OZ5 A;  3GXH A;  3D42 A;  1OHC A;  2I4G A;  1OEO X;  1KAK A;  2F6Z A;  2WJP A;  4RHG A;  3O3L A;  2F6V A;  3S3F A;  2QDP A;  3QCL A;  3U96 A;  4C12 A;  4RKK A;  2B3O A;  4ZRT A;  5BZZ A;  2NV5 A;  2VTD A;  3RGQ A;  3RO1 A;  2Y1O A;  2C7S A;  2NTA A;  1NL9 A;  2WTZ A;  1XXP A;  1FQ1 A;  3A5J A;  1AAX A;  4NX8 A;  2H02 A;  1GG4 A;  3QKP A;  3ZMQ A;  1D5R A;  1P31 A;  1FGS A;  4OHD A;  2M3V A;  4GFU A;  1ONZ A;  5A5E A;  1MKP A;  4OHH A;  3D9C A;  3S3H A;  2B4O A;  3QCC A;  1BZC A;  3F9A A;  3N0A A;  5J8R A;  1JBV A;  2PA5 A; 
#chains in the Genus database with same CATH homology
 4GS0 A;  1YN9 A;  5AWX A;  4QUM A;  4RI4 A;  1PTY A;  1T49 A;  2CNH A;  4WU2 A;  2FH7 A;  1G1F A;  1Q6M A;  2CM2 A;  2CMA A;  3QCG A;  2B07 A;  2H03 A;  2G6Z A;  4RH9 A;  4Y14 A;  2H4G A;  4WTY A;  3I7Z A;  4ZN5 A;  3ZM1 A;  2J16 B;  4GE5 A;  1G7G A;  1Q1M A;  2B4P A;  4OHI A;  2A3K A;  3PS5 A;  4OHE A;  1YTN A;  2F70 A;  3ZV2 A;  1V3A A;  2CM3 A;  2C46 A;  3BRH A;  2BZL A;  2NT7 A;  4JNB A;  2MBC A;  2PT0 A;  4ERC A;  4JBC A;  5KA4 A;  2F6Y A;  1YWF A;  2VEW A;  2B4S A;  5KA8 A;  2NLK A;  3ZM2 A;  1GWZ A;  2DXP A;  3QCN A;  4PYH A;  4ICZ A;  2CNI A;  1JLN A;  5K23 A;  1RPM A;  4RH5 A;  4D3P A;  3ZM0 A;  2CFV A;  3ZM3 A;  1YGU A;  4RDD A;  1YTW A;  2YDU A;  1T48 A;  5BUG A;  3D1Q A;  3QKQ A;  5BX1 A;  2CJZ A;  2ESB A;  2CNE A;  5K9W A;  5KAA A;  3EB1 A;  2H4V A;  1X24 A;  1XRI A;  5EHR A;  1XXV A;  2I6M A;  3I80 A;  3OMH A;  1I9T A;  3EZZ A;  3MOW A;  4H34 A;  4NYH A;  2J16 A;  4PVG A;  1QXK A;  1GFY A;  3SME A;  3V0F A;  2F46 A;  1JF7 A;  2Y2F A;  4ZI4 A;  3RGO A;  4D3R A;  2ZN7 A;  4DGX A;  3O4U A;  4WU3 A;  2HY3 A;  2SHP A;  4GE2 A;  4GWF A;  2H04 A;  2I6O A;  4NND A;  5KAD A;  2QBQ A;  4GRY A;  5K25 A;  4Z6B A;  3V0I A;  2AZR A;  2CMB A;  4JMK A;  3GXG A;  2A8B A;  3QCB A;  2PSZ A;  3D44 A;  2AHS A;  3H2X A;  4KYR A;  2BV5 A;  2P6X A;  4IKC A;  5KA2 A;  1VHR A;  3D1H A;  2H4K A;  1ECV A;  2NZ6 A;  1QZ0 A;  2VEU A;  3V0D A;  5LXQ B;  1J4X A;  1G1H A;  2QBP A;  4TVV A;  3CWE A;  4YAA A;  4HRF A;  1Q6S A;  2PI7 A;  2I5X A;  2I3R A;  2OOQ A;  1XBO A;  4QBW A;  5KA7 A;  4NWF A;  1KAV A;  1PTV A;  1C88 A;  2I4H A;  1G7F A;  3MOZ A;  1NNY A;  1NWL A;  5KA0 A;  2I1Y A;  2OUD A;  2GWO A;  4OHL A;  2FJM A;  1RXD A;  2CMC A;  1C87 A;  2QCJ A;  1NZ7 A;  2I6I A;  3QCF A;  3O4T A;  1YTS A;  5MMZ B;  1PTU A;  1FPZ A;  1SUG A;  2CNF A;  2F71 A;  5K9V A;  5M43 A;  1OET A;  1FPR A;  3I36 A;  3QCJ A;  1OEM X;  1G4U S;  2QBR A;  1NWE A;  5IBS A;  4WOH A;  1C86 A;  4Y2E A;  3QCI A;  1Q6P A;  3QCE A;  2VEV A;  2I6J A;  3A5K A;  3SR9 A;  4S0G A;  2QBS A;  1YPT A;  2BGD A;  2PBN A;  4R0S A;  5HDE A;  4GRZ A;  2QEP A;  4QBE A;  3CM3 A;  3BLU A;  1L8G A;  2I75 A;  2CNG A;  2ZMM A;  1WAX A;  5K24 A;  5GTJ A;  1PA9 A;  3AWG A;  2FJN A;  2E0T A;  4QAH A;  2PQ5 A;  3AWE A;  3QCD A;  4RI5 A;  2F6T A;  3LJ8 A;  1P15 A;  1T4J A;  5KA9 A;  1BZH A;  5KAC A;  3O4S A;  2VEY A;  2HNQ A;  4D3Q A;  2I6P A;  4BPC A;  3S4E A;  1OHD A;  3QCH A;  3D1O A;  2QDM A;  4HJP A;  1U25 A;  1BZJ A;  3BLT A;  2HVL A;  2QDC A;  2B49 A;  1LAR A;  1ZCK A;  2I4E A;  1ZZW A;  2J17 A;  2P4D A;  4QAP A;  1EEO A;  1WCH A;  1G1G A;  2CM7 A;  5EHP A;  4J51 A;  5IBM A;  1M3G A;  4HJQ A;  1I57 A;  1YFO A;  2G59 A;  2GJT A;  1Q6T A;  3F99 A;  1G4W R;  1ONY A;  3EMU A;  1YZ4 A;  2I42 A;  3S3K A;  2HB1 A;  4AZ1 A;  2RF6 A;  2JJD A;  1C83 A;  1PA1 A;  1I9S A;  1U26 A;  1U24 A;  1PYN A;  2HC1 A;  4R0T A;  5BZX A;  4DGP A;  3OLR A;  1Q6N A;  4KYQ A;  3S3E A;  1WRM A;  4I8N A;  1R6H A;  2HXP A;  1OEV A;  2Q05 A;  1Q6J A;  1YGR A;  1EEN A;  4BJO A;  3RZ2 A;  1L8K A;  3QCK A;  2I3U A;  2VEX A;  1C84 A;  2IMG A;  3QCM A;  3F9B A;  5I6V A;  1OES A;  4NWG A;  3V0G A;  3V0H A;  3EU0 A;  2F6W A;  2HNP A;  4GE6 A;  4R30 A;  1PTT A;  2F6F A;  1A5Y A;  3NME A;  3EAX A;  3MMJ A;  3V0E A;  2CM8 A;  3F41 A;  2NT2 A;  4KI9 A;  2QCT A;  1OEU A;  4JMJ A;  2WGP A;  1LQF A;  3V0J A;  3M4U A;  5KAB A;  4YR8 B;  1LYV A;  1OHE A;  3BM8 A;  1PH0 A;  1XM2 A;  5KA1 A;  2BIJ A;  3O5X A;  4QUN A;  2OC3 A;  1C85 A;  2Y96 A;  2GP0 A;  2BGE A;  2R0B A;  4H1O A;  4GFV A;  2HC2 A;  1ZC0 A;  1NO6 A;  4B04 A;  2Q47 A;  3AWF A;  1PXH A;  3ZMP A;  2HCM A;  3F81 A;  4MBB A;  5K22 A;  3B7O A;  2B4U A;  3S4O A;  1ZCL A;  5KA3 A;  2OZ5 A;  3GXH A;  3D42 A;  1OHC A;  2I4G A;  1OEO X;  1KAK A;  2F6Z A;  4RHG A;  3O3L A;  2F6V A;  3S3F A;  2QDP A;  3QCL A;  3U96 A;  4RKK A;  2B3O A;  4ZRT A;  5BZZ A;  2NV5 A;  3RGQ A;  3RO1 A;  2C7S A;  2NTA A;  1NL9 A;  1XXP A;  1FQ1 A;  3A5J A;  1AAX A;  4NX8 A;  2H02 A;  3QKP A;  3ZMQ A;  1D5R A;  4OHD A;  2M3V A;  4GFU A;  1ONZ A;  1MKP A;  4OHH A;  3D9C A;  3S3H A;  2B4O A;  3QCC A;  1BZC A;  3F9A A;  3N0A A;  5J8R A;  2PA5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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