2F6TA

Protein tyrosine phosphatase 1b with sulfamic acid inhibitors
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase, non-receptor type 1
total genus 112
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2005-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2f6tA00
2HC2A 1G4US 2C46A 1QZ0A 1OEOX 5LXQB 3S3FA 1WRMA 2QDCA 4GE6A 3N0AA 2H02A 3D42A 3D44A 1XXPA 3QCMA 5MMZB 2RF6A 2QBSA 4I8NA 1I57A 1NZ7A 1Q1MA 1OHDA 2I6MA 5KA7A 4HJQA 1YPTA 1PTUA 1A5YA 5IBSA 1C85A 3V0JA 4DGPA 4RH9A 2I3RA 1NWLA 1QXKA 4WOHA 2B3OA 2VEWA 3H2XA 4QBEA 4QUMA 3V0IA 4NYHA 3QCNA 1ZCKA 3LJ8A 5KACA 1YFOA 1ZC0A 1YGUA 3OLRA 1ECVA 2HNPA 1NO6A 2QDPA 2QCJA 2FH7A 4YAAA 2FJMA 1Q6MA 3CWEA 2CM7A 5AWXA 2PA5A 2AZRA 2CM2A 2QBQA 2NT7A 3BLUA 3QCDA 4R30A 5K22A 5BZXA 2DXPA 1YGRA 3O5XA 1VHRA 4DGXA 3QCLA 4NWFA 2CMBA 2F6VA 2G59A 2HCMA 1C87A 3EAXA 5K9VA 1D5RA 1T49A 2I6OA 3F81A 5BUGA 4D3QA 1L8KA 3D1HA 2OZ5A 2B4SA 4KYQA 3RZ2A 2Y2FA 2MBCA 3MOWA 5KA0A 3F9BA 2I1YA 2BZLA 3I7ZA 1ZZWA 1OEVA 2B4OA 3QCJA 1RPMA 3ZM3A 2I75A 2VEYA 4NX8A 1MKPA 1NNYA 4PYHA 3S4EA 4GFUA 1JF7A 2J17A 2PSZA 2A8BA 1OETA 3QCFA 2F6WA 2BIJA 1KAKA 3O4SA 3QKPA 3V0DA 2F71A 4QUNA 3ZM0A 4QBWA 2CNGA 1OEMX 1U25A 1Q6SA 1PXHA 1ONYA 3MOZA 2H4GA 2I3UA 1RXDA 3AWGA 2F6YA 3V0EA 2NT2A 4WU3A 2SHPA 4D3PA 3EMUA 2VEVA 1Q6PA 2GP0A 1ZCLA 2J16B 1Q6NA 2I6PA 3S3EA 2J16A 1LYVA 3U96A 1OHCA 2VEXA 2I4GA 3B7OA 1FPZA 5K25A 2CNIA 1GWZA 4R0TA 1V3AA 1G1HA 3MMJA 2HVLA 2H04A 5IBMA 5K9WA 2P4DA 2H03A 4YR8B 3QKQA 4TVVA 5KA1A 2AHSA 2CMCA 1G7FA 2R0BA 4BJOA 1T48A 1PA1A 2M3VA 2Y96A 1C88A 4H34A 5I6VA 3BRHA 4H1OA 2QBPA 4AZ1A 3QCBA 2QBRA 4QAPA 1PA9A 1PYNA 3CM3A 2CFVA 1YTWA 4KI9A 1FQ1A 5KADA 3M4UA 5KABA 1P15A 1C86A 2CJZA 1FPRA 2CM3A 4RDDA 5KA2A 4WU2A 1T4JA 3PS5A 3ZMPA 1I9SA 2YDUA 4S0GA 4GRZA 4JBCA 3RO1A 5KA3A 2B07A 4JNBA 1EENA 4RI5A 4HJPA 4NNDA 4GE2A 4B04A 4IKCA 4ZRTA 1BZJA 1YWFA 4RKKA 2GJTA 1PTTA 1JLNA 4ZI4A 2H4VA 5KA4A 3I36A 2BGEA 2CNFA 4PVGA 1J4XA 4RH5A 1LARA 3BM8A 1OHEA 2QCTA 3A5KA 3QCGA 1I9TA 4OHEA 3V0HA 1NL9A 2OC3A 2NLKA 1G7GA 1AAXA 1Q6JA 3F9AA 1YN9A 4OHLA 3ZV2A 2OUDA 4ICZA 3RGOA 1U24A 3BLTA 3EB1A 3OMHA 3ZM1A 2G6ZA 2QEPA 4BPCA 2FJNA 1SUGA 2ZN7A 4KYRA 3SR9A 4HRFA 3D1OA 4Z6BA 4OHHA 5HDEA 2B4UA 4Y14A 4ERCA 3QCIA 1EEOA 2ESBA 3O3LA 4GS0A 5KA9A 2PT0A 5EHRA 1XXVA 5J8RA 2GWOA 4JMJA 2P6XA 2IMGA 4R0SA 5BX1A 4WTYA 3GXGA 4OHIA 2OOQA 5K23A 1LQFA 1BZHA 1PTYA 4GE5A 3O4UA 4GWFA 2F6FA 2I4EA 3QCHA 1KAVA 2QDMA 1G1GA 2I4HA 1U26A 2WGPA 1C84A 4NWGA 2HY3A 5KAAA 1OESA 2BGDA 4Y2EA 4ZN5A 2PQ5A 4D3RA 3QCKA 3S3KA 3RGQA 1ONZA 2ZMMA 3NMEA 3S4OA 1YTNA 1WCHA 4JMKA 1XM2A 5M43A 2Q47A 2NZ6A 5KA8A 2E0TA 1BZCA 4MBBA 4J51A 2HNQA 1PH0A 1M3GA 1PTVA 3GXHA 1R6HA 2CM8A 4QAHA 2VEUA 2CNEA 2HXPA 2H4KA 5GTJA 2I6IA 2F70A 5K24A 2CNHA 2NV5A 2B49A 3SMEA 2C7SA 2PBNA 2F46A 1X24A 4GRYA 3ZM2A 3QCEA 1WAXA 3S3HA 2F6ZA 2BV5A 1YZ4A 3F99A 3AWEA 3F41A 1G1FA 2NTAA 3D1QA 4RHGA 1L8GA 1OEUA 1Q6TA 2HB1A 3EU0A 1XRIA 3AWFA 1GFYA 1NWEA 4GFVA 2JJDA 3V0FA 2B4PA 2I6JA 3EZZA 2HC1A 2CMAA 2F6TA 1XBOA 4OHDA 3V0GA 3A5JA 2I42A 2A3KA 3QCCA 3D9CA 4RI4A 1YTSA 3ZMQA 2I5XA 3O4TA 5EHPA 5BZZA 3I80A 1G4WR 2PI7A 2Q05A 1C83A
chains in the Genus database with same CATH superfamily
2HC2A 1G4US 2C46A 1QZ0A 2F00A 1OEOX 5LXQB 3S3FA 1WRMA 2QDCA 4GE6A 3N0AA 2H02A 3D42A 3D44A 1XXPA 3QCMA 5MMZB 2RF6A 2QBSA 2VOSA 4I8NA 1I57A 1NZ7A 1Q1MA 1OHDA 2I6MA 5KA7A 4HJQA 1YPTA 1PTUA 1A5YA 5IBSA 1EEHA 2Y66A 1C85A 3V0JA 4DGPA 4RH9A 2I3RA 1NWLA 1E8CA 4C13A 4CVKA 1QXKA 4WOHA 2B3OA 4CVMA 2VEWA 3H2XA 4QBEA 4QUMA 3V0IA 4NYHA 3QCNA 1ZCKA 3LJ8A 4UAGA 1JBWA 2JFFA 5KACA 2UUOA 1YFOA 1ZC0A 1YGUA 3OLRA 1ECVA 2HNPA 1NO6A 2QDPA 2QCJA 2FH7A 4YAAA 2FJMA 1Q6MA 3CWEA 2CM7A 5AWXA 2X5OA 2PA5A 2AZRA 2UUPA 2CM2A 2QBQA 2NT7A 3BLUA 3QCDA 4R30A 5K22A 5BZXA 2DXPA 1YGRA 3O5XA 1VHRA 4DGXA 3QCLA 4NWFA 2CMBA 2F6VA 2G59A 2HCMA 4C12A 1C87A 3EAXA 5K9VA 1D5RA 1T49A 2I6OA 3F81A 5BUGA 4D3QA 1L8KA 3D1HA 2OZ5A 3PYZA 2B4SA 4KYQA 3RZ2A 2Y2FA 2MBCA 3MOWA 5A5FA 5KA0A 3F9BA 2I1YA 2BZLA 3I7ZA 1ZZWA 2AM2A 1OEVA 2B4OA 3QCJA 1RPMA 3ZM3A 2I75A 2VEYA 4NX8A 1MKPA 1NNYA 4PYHA 4QDIA 3S4EA 4GFUA 4BUBA 1O5ZA 1JF7A 4ZIYA 2J17A 2PSZA 2A8BA 1OETA 3QCFA 2F6WA 2BIJA 1KAKA 3O4SA 3QKPA 3V0DA 2F71A 4QUNA 1GQQA 3ZM0A 4QBWA 2CNGA 2Y67A 1OEMX 1U25A 1Q6SA 1PXHA 1ONYA 3MOZA 2H4GA 2I3UA 2Y1OA 1UAGA 1RXDA 3AWGA 2F6YA 3V0EA 2NT2A 4WU3A 2SHPA 1E0DA 4D3PA 3EMUA 2VEVA 1Q6PA 2GP0A 1ZCLA 2J16B 1Q6NA 2I6PA 3S3EA 2J16A 1LYVA 3U96A 1OHCA 2VEXA 2I4GA 3B7OA 4HV4A 1FPZA 5K25A 2CNIA 3ZM5A 1GWZA 2VTDA 4R0TA 1V3AA 1G1HA 3MMJA 2HVLA 2H04A 5IBMA 5K9WA 2GCBA 2P4DA 2H03A 4YR8B 3QKQA 4TVVA 5KA1A 2AHSA 2CMCA 2Y68A 1G7FA 2GC5A 2R0BA 4BJOA 1T48A 1PA1A 2M3VA 1GQYA 2Y96A 1C88A 4H34A 5I6VA 3BRHA 4H1OA 2QBPA 4AZ1A 3QCBA 2QBRA 4QAPA 1PA9A 1PYNA 4QF5A 3CM3A 2CFVA 1YTWA 4KI9A 1FQ1A 1P31A 5KADA 3UAGA 3M4UA 5KABA 1P15A 1C86A 2CJZA 1FPRA 3MVNA 3ZL8A 2CM3A 4RDDA 5KA2A 4WU2A 1T4JA 3PS5A 3ZMPA 1I9SA 2YDUA 2VTEA 1FGSA 4S0GA 4GRZA 4JBCA 3RO1A 5KA3A 2B07A 4JNBA 1EENA 4RI5A 4HJPA 4NNDA 4GE2A 4B04A 4IKCA 5A5EA 4ZRTA 1BZJA 1YWFA 4RKKA 1J6UA 2GJTA 1PTTA 1JLNA 4ZI4A 2H4VA 2VORA 5KA4A 4BUCA 2UAGA 3I36A 2BGEA 2CNFA 4PVGA 1J4XA 4RH5A 1LARA 3BM8A 1OHEA 2QCTA 3A5KA 3QCGA 1I9TA 4OHEA 3V0HA 1NL9A 2OC3A 2NLKA 1G7GA 1AAXA 2XPCA 1Q6JA 3F9AA 3N2AA 1YN9A 4OHLA 3ZV2A 2OUDA 4ICZA 3RGOA 1U24A 3BLTA 3EB1A 3OMHA 3ZM1A 2G6ZA 2QEPA 4BPCA 2FJNA 1SUGA 2ZN7A 4KYRA 3SR9A 4HRFA 3D1OA 4Z6BA 4OHHA 5HDEA 2B4UA 4Y14A 4ERCA 3QCIA 1EEOA 2ESBA 3O3LA 4GS0A 5KA9A 2PT0A 5EHRA 1XXVA 3QCZA 5J8RA 2GWOA 4JMJA 2P6XA 2IMGA 4R0SA 5BX1A 4WTYA 3GXGA 2JFHA 4OHIA 2OOQA 5K23A 1LQFA 1BZHA 1PTYA 4GE5A 3O4UA 4GWFA 2F6FA 2I4EA 3QCHA 1KAVA 2QDMA 2WJPA 1G1GA 2AM1A 2I4HA 1U26A 2WGPA 1C84A 4NWGA 2HY3A 5KAAA 1OESA 2BGDA 3HN7A 4Y2EA 4ZN5A 1GG4A 2PQ5A 4D3RA 3QCKA 3S3KA 1P3DA 3RGQA 1ONZA 2ZMMA 3NMEA 3S4OA 1YTNA 1WCHA 4JMKA 1XM2A 5M43A 2Q47A 2NZ6A 5KA8A 2E0TA 1BZCA 4MBBA 4J51A 2HNQA 1PH0A 1M3GA 1PTVA 3GXHA 1JBVA 1R6HA 2CM8A 2WTZA 4QAHA 2JFGA 2VEUA 2CNEA 2HXPA 2H4KA 5GTJA 2I6IA 2F70A 5K24A 2CNHA 2NV5A 2B49A 3SMEA 2C7SA 2PBNA 2F46A 1X24A 4GRYA 3ZM2A 3ZM6A 3QCEA 1WAXA 3S3HA 2F6ZA 2BV5A 3LK7A 1YZ4A 3F99A 3AWEA 3F41A 1G1FA 2NTAA 3D1QA 4RHGA 1L8GA 1OEUA 1Q6TA 2HB1A 3EU0A 1XRIA 3AWFA 1W78A 1GFYA 1NWEA 3NRSA 4GFVA 2JJDA 3V0FA 2B4PA 2I6JA 3EZZA 2HC1A 2CMAA 2GCAA 2F6TA 1XBOA 4OHDA 3V0GA 2XJAA 3A5JA 2I42A 2A3KA 3QCCA 3D9CA 4CVLA 4RI4A 1YTSA 1W7KA 3ZMQA 2I5XA 3O4TA 5EHPA 5BZZA 2GC6A 3I80A 1G4WR 2PI7A 2Q05A 1C83A
chains in the Genus database with same CATH topology
2HC2A 1G4US 2C46A 1QZ0A 1OEOX 5LXQB 3S3FA 1WRMA 2QDCA 4GE6A 3N0AA 2H02A 3D42A 3D44A 1XXPA 3QCMA 5MMZB 2RF6A 2QBSA 4I8NA 1I57A 1NZ7A 1Q1MA 1OHDA 2I6MA 5KA7A 4HJQA 1YPTA 1PTUA 1A5YA 5IBSA 1C85A 3V0JA 4DGPA 4RH9A 2I3RA 1NWLA 1QXKA 4WOHA 2B3OA 2VEWA 3H2XA 4QBEA 4QUMA 3V0IA 4NYHA 3QCNA 1ZCKA 3LJ8A 5KACA 1YFOA 1ZC0A 1YGUA 3OLRA 1ECVA 2HNPA 1NO6A 2QDPA 2QCJA 2FH7A 4YAAA 2FJMA 1Q6MA 3CWEA 2CM7A 5AWXA 2PA5A 2AZRA 2CM2A 2QBQA 2NT7A 3BLUA 3QCDA 4R30A 5K22A 5BZXA 2DXPA 1YGRA 3O5XA 1VHRA 4DGXA 3QCLA 4NWFA 2CMBA 2F6VA 2G59A 2HCMA 1C87A 3EAXA 5K9VA 1D5RA 1T49A 2I6OA 3F81A 5BUGA 4D3QA 1L8KA 3D1HA 2OZ5A 2B4SA 4KYQA 3RZ2A 2Y2FA 2MBCA 3MOWA 5KA0A 3F9BA 2I1YA 2BZLA 3I7ZA 1ZZWA 1OEVA 2B4OA 3QCJA 1RPMA 3ZM3A 2I75A 2VEYA 4NX8A 1MKPA 1NNYA 4PYHA 3S4EA 4GFUA 1JF7A 2J17A 2PSZA 2A8BA 1OETA 3QCFA 2F6WA 2BIJA 1KAKA 3O4SA 3QKPA 3V0DA 2F71A 4QUNA 3ZM0A 4QBWA 2CNGA 1OEMX 1U25A 1Q6SA 1PXHA 1ONYA 3MOZA 2H4GA 2I3UA 1RXDA 3AWGA 2F6YA 3V0EA 2NT2A 4WU3A 2SHPA 4D3PA 3EMUA 2VEVA 1Q6PA 2GP0A 1ZCLA 2J16B 1Q6NA 2I6PA 3S3EA 2J16A 1LYVA 3U96A 1OHCA 2VEXA 2I4GA 3B7OA 1FPZA 5K25A 2CNIA 1GWZA 4R0TA 1V3AA 1G1HA 3MMJA 2HVLA 2H04A 5IBMA 5K9WA 2P4DA 2H03A 4YR8B 3QKQA 4TVVA 5KA1A 2AHSA 2CMCA 1G7FA 2R0BA 4BJOA 1T48A 1PA1A 2M3VA 2Y96A 1C88A 4H34A 5I6VA 3BRHA 4H1OA 2QBPA 4AZ1A 3QCBA 2QBRA 4QAPA 1PA9A 1PYNA 3CM3A 2CFVA 1YTWA 4KI9A 1FQ1A 5KADA 3M4UA 5KABA 1P15A 1C86A 2CJZA 1FPRA 2CM3A 4RDDA 5KA2A 4WU2A 1T4JA 3PS5A 3ZMPA 1I9SA 2YDUA 4S0GA 4GRZA 4JBCA 3RO1A 5KA3A 2B07A 4JNBA 1EENA 4RI5A 4HJPA 4NNDA 4GE2A 4B04A 4IKCA 4ZRTA 1BZJA 1YWFA 4RKKA 2GJTA 1PTTA 1JLNA 4ZI4A 2H4VA 5KA4A 3I36A 2BGEA 2CNFA 4PVGA 1J4XA 4RH5A 1LARA 3BM8A 1OHEA 2QCTA 3A5KA 3QCGA 1I9TA 4OHEA 3V0HA 1NL9A 2OC3A 2NLKA 1G7GA 1AAXA 1Q6JA 3F9AA 1YN9A 4OHLA 3ZV2A 2OUDA 4ICZA 3RGOA 1U24A 3BLTA 3EB1A 3OMHA 3ZM1A 2G6ZA 2QEPA 4BPCA 2FJNA 1SUGA 2ZN7A 4KYRA 3SR9A 4HRFA 3D1OA 4Z6BA 4OHHA 5HDEA 2B4UA 4Y14A 4ERCA 3QCIA 1EEOA 2ESBA 3O3LA 4GS0A 5KA9A 2PT0A 5EHRA 1XXVA 5J8RA 2GWOA 4JMJA 2P6XA 2IMGA 4R0SA 5BX1A 4WTYA 3GXGA 4OHIA 2OOQA 5K23A 1LQFA 1BZHA 1PTYA 4GE5A 3O4UA 4GWFA 2F6FA 2I4EA 3QCHA 1KAVA 2QDMA 1G1GA 2I4HA 1U26A 2WGPA 1C84A 4NWGA 2HY3A 5KAAA 1OESA 2BGDA 4Y2EA 4ZN5A 2PQ5A 4D3RA 3QCKA 3S3KA 3RGQA 1ONZA 2ZMMA 3NMEA 3S4OA 1YTNA 1WCHA 4JMKA 1XM2A 5M43A 2Q47A 2NZ6A 5KA8A 2E0TA 1BZCA 4MBBA 4J51A 2HNQA 1PH0A 1M3GA 1PTVA 3GXHA 1R6HA 2CM8A 4QAHA 2VEUA 2CNEA 2HXPA 2H4KA 5GTJA 2I6IA 2F70A 5K24A 2CNHA 2NV5A 2B49A 3SMEA 2C7SA 2PBNA 2F46A 1X24A 4GRYA 3ZM2A 3QCEA 1WAXA 3S3HA 2F6ZA 2BV5A 1YZ4A 3F99A 3AWEA 3F41A 1G1FA 2NTAA 3D1QA 4RHGA 1L8GA 1OEUA 1Q6TA 2HB1A 3EU0A 1XRIA 3AWFA 1GFYA 1NWEA 4GFVA 2JJDA 3V0FA 2B4PA 2I6JA 3EZZA 2HC1A 2CMAA 2F6TA 1XBOA 4OHDA 3V0GA 3A5JA 2I42A 2A3KA 3QCCA 3D9CA 4RI4A 1YTSA 3ZMQA 2I5XA 3O4TA 5EHPA 5BZZA 3I80A 1G4WR 2PI7A 2Q05A 1C83A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HC2 A;  1G4U S;  2C46 A;  1QZ0 A;  1OEO X;  5LXQ B;  3S3F A;  1WRM A;  2QDC A;  4GE6 A;  3N0A A;  2H02 A;  3D42 A;  3D44 A;  1XXP A;  3QCM A;  5MMZ B;  2RF6 A;  2QBS A;  4I8N A;  1I57 A;  1NZ7 A;  1Q1M A;  1OHD A;  2I6M A;  5KA7 A;  4HJQ A;  1YPT A;  1PTU A;  1A5Y A;  5IBS A;  1C85 A;  3V0J A;  4DGP A;  4RH9 A;  2I3R A;  1NWL A;  1QXK A;  4WOH A;  2B3O A;  2VEW A;  3H2X A;  4QBE A;  4QUM A;  3V0I A;  4NYH A;  3QCN A;  1ZCK A;  3LJ8 A;  5KAC A;  1YFO A;  1ZC0 A;  1YGU A;  3OLR A;  1ECV A;  2HNP A;  1NO6 A;  2QDP A;  2QCJ A;  2FH7 A;  4YAA A;  2FJM A;  1Q6M A;  3CWE A;  2CM7 A;  5AWX A;  2PA5 A;  2AZR A;  2CM2 A;  2QBQ A;  2NT7 A;  3BLU A;  3QCD A;  4R30 A;  5K22 A;  5BZX A;  2DXP A;  1YGR A;  3O5X A;  1VHR A;  4DGX A;  3QCL A;  4NWF A;  2CMB A;  2F6V A;  2G59 A;  2HCM A;  1C87 A;  3EAX A;  5K9V A;  1D5R A;  1T49 A;  2I6O A;  3F81 A;  5BUG A;  4D3Q A;  1L8K A;  3D1H A;  2OZ5 A;  2B4S A;  4KYQ A;  3RZ2 A;  2Y2F A;  2MBC A;  3MOW A;  5KA0 A;  3F9B A;  2I1Y A;  2BZL A;  3I7Z A;  1ZZW A;  1OEV A;  2B4O A;  3QCJ A;  1RPM A;  3ZM3 A;  2I75 A;  2VEY A;  4NX8 A;  1MKP A;  1NNY A;  4PYH A;  3S4E A;  4GFU A;  1JF7 A;  2J17 A;  2PSZ A;  2A8B A;  1OET A;  3QCF A;  2F6W A;  2BIJ A;  1KAK A;  3O4S A;  3QKP A;  3V0D A;  2F71 A;  4QUN A;  3ZM0 A;  4QBW A;  2CNG A;  1OEM X;  1U25 A;  1Q6S A;  1PXH A;  1ONY A;  3MOZ A;  2H4G A;  2I3U A;  1RXD A;  3AWG A;  2F6Y A;  3V0E A;  2NT2 A;  4WU3 A;  2SHP A;  4D3P A;  3EMU A;  2VEV A;  1Q6P A;  2GP0 A;  1ZCL A;  2J16 B;  1Q6N A;  2I6P A;  3S3E A;  2J16 A;  1LYV A;  3U96 A;  1OHC A;  2VEX A;  2I4G A;  3B7O A;  1FPZ A;  5K25 A;  2CNI A;  1GWZ A;  4R0T A;  1V3A A;  1G1H A;  3MMJ A;  2HVL A;  2H04 A;  5IBM A;  5K9W A;  2P4D A;  2H03 A;  4YR8 B;  3QKQ A;  4TVV A;  5KA1 A;  2AHS A;  2CMC A;  1G7F A;  2R0B A;  4BJO A;  1T48 A;  1PA1 A;  2M3V A;  2Y96 A;  1C88 A;  4H34 A;  5I6V A;  3BRH A;  4H1O A;  2QBP A;  4AZ1 A;  3QCB A;  2QBR A;  4QAP A;  1PA9 A;  1PYN A;  3CM3 A;  2CFV A;  1YTW A;  4KI9 A;  1FQ1 A;  5KAD A;  3M4U A;  5KAB A;  1P15 A;  1C86 A;  2CJZ A;  1FPR A;  2CM3 A;  4RDD A;  5KA2 A;  4WU2 A;  1T4J A;  3PS5 A;  3ZMP A;  1I9S A;  2YDU A;  4S0G A;  4GRZ A;  4JBC A;  3RO1 A;  5KA3 A;  2B07 A;  4JNB A;  1EEN A;  4RI5 A;  4HJP A;  4NND A;  4GE2 A;  4B04 A;  4IKC A;  4ZRT A;  1BZJ A;  1YWF A;  4RKK A;  2GJT A;  1PTT A;  1JLN A;  4ZI4 A;  2H4V A;  5KA4 A;  3I36 A;  2BGE A;  2CNF A;  4PVG A;  1J4X A;  4RH5 A;  1LAR A;  3BM8 A;  1OHE A;  2QCT A;  3A5K A;  3QCG A;  1I9T A;  4OHE A;  3V0H A;  1NL9 A;  2OC3 A;  2NLK A;  1G7G A;  1AAX A;  1Q6J A;  3F9A A;  1YN9 A;  4OHL A;  3ZV2 A;  2OUD A;  4ICZ A;  3RGO A;  1U24 A;  3BLT A;  3EB1 A;  3OMH A;  3ZM1 A;  2G6Z A;  2QEP A;  4BPC A;  2FJN A;  1SUG A;  2ZN7 A;  4KYR A;  3SR9 A;  4HRF A;  3D1O A;  4Z6B A;  4OHH A;  5HDE A;  2B4U A;  4Y14 A;  4ERC A;  3QCI A;  1EEO A;  2ESB A;  3O3L A;  4GS0 A;  5KA9 A;  2PT0 A;  5EHR A;  1XXV A;  5J8R A;  2GWO A;  4JMJ A;  2P6X A;  2IMG A;  4R0S A;  5BX1 A;  4WTY A;  3GXG A;  4OHI A;  2OOQ A;  5K23 A;  1LQF A;  1BZH A;  1PTY A;  4GE5 A;  3O4U A;  4GWF A;  2F6F A;  2I4E A;  3QCH A;  1KAV A;  2QDM A;  1G1G A;  2I4H A;  1U26 A;  2WGP A;  1C84 A;  4NWG A;  2HY3 A;  5KAA A;  1OES A;  2BGD A;  4Y2E A;  4ZN5 A;  2PQ5 A;  4D3R A;  3QCK A;  3S3K A;  3RGQ A;  1ONZ A;  2ZMM A;  3NME A;  3S4O A;  1YTN A;  1WCH A;  4JMK A;  1XM2 A;  5M43 A;  2Q47 A;  2NZ6 A;  5KA8 A;  2E0T A;  1BZC A;  4MBB A;  4J51 A;  2HNQ A;  1PH0 A;  1M3G A;  1PTV A;  3GXH A;  1R6H A;  2CM8 A;  4QAH A;  2VEU A;  2CNE A;  2HXP A;  2H4K A;  5GTJ A;  2I6I A;  2F70 A;  5K24 A;  2CNH A;  2NV5 A;  2B49 A;  3SME A;  2C7S A;  2PBN A;  2F46 A;  1X24 A;  4GRY A;  3ZM2 A;  3QCE A;  1WAX A;  3S3H A;  2F6Z A;  2BV5 A;  1YZ4 A;  3F99 A;  3AWE A;  3F41 A;  1G1F A;  2NTA A;  3D1Q A;  4RHG A;  1L8G A;  1OEU A;  1Q6T A;  2HB1 A;  3EU0 A;  1XRI A;  3AWF A;  1GFY A;  1NWE A;  4GFV A;  2JJD A;  3V0F A;  2B4P A;  2I6J A;  3EZZ A;  2HC1 A;  2CMA A;  2F6T A;  1XBO A;  4OHD A;  3V0G A;  3A5J A;  2I42 A;  2A3K A;  3QCC A;  3D9C A;  4RI4 A;  1YTS A;  3ZMQ A;  2I5X A;  3O4T A;  5EHP A;  5BZZ A;  3I80 A;  1G4W R;  2PI7 A;  2Q05 A;  1C83 A; 
#chains in the Genus database with same CATH topology
 2HC2 A;  1G4U S;  2C46 A;  1QZ0 A;  2F00 A;  1OEO X;  5LXQ B;  3S3F A;  1WRM A;  2QDC A;  4GE6 A;  3N0A A;  2H02 A;  3D42 A;  3D44 A;  1XXP A;  3QCM A;  5MMZ B;  2RF6 A;  2QBS A;  2VOS A;  4I8N A;  1I57 A;  1NZ7 A;  1Q1M A;  1OHD A;  2I6M A;  5KA7 A;  4HJQ A;  1YPT A;  1PTU A;  1A5Y A;  5IBS A;  1EEH A;  2Y66 A;  1C85 A;  3V0J A;  4DGP A;  4RH9 A;  2I3R A;  1NWL A;  1E8C A;  4C13 A;  4CVK A;  1QXK A;  4WOH A;  2B3O A;  4CVM A;  2VEW A;  3H2X A;  4QBE A;  4QUM A;  3V0I A;  4NYH A;  3QCN A;  1ZCK A;  3LJ8 A;  4UAG A;  1JBW A;  2JFF A;  5KAC A;  2UUO A;  1YFO A;  1ZC0 A;  1YGU A;  3OLR A;  1ECV A;  2HNP A;  1NO6 A;  2QDP A;  2QCJ A;  2FH7 A;  4YAA A;  2FJM A;  1Q6M A;  3CWE A;  2CM7 A;  5AWX A;  2X5O A;  2PA5 A;  2AZR A;  2UUP A;  2CM2 A;  2QBQ A;  2NT7 A;  3BLU A;  3QCD A;  4R30 A;  5K22 A;  5BZX A;  2DXP A;  1YGR A;  3O5X A;  1VHR A;  4DGX A;  3QCL A;  4NWF A;  2CMB A;  2F6V A;  2G59 A;  2HCM A;  4C12 A;  1C87 A;  3EAX A;  5K9V A;  1D5R A;  1T49 A;  2I6O A;  3F81 A;  5BUG A;  4D3Q A;  1L8K A;  3D1H A;  2OZ5 A;  3PYZ A;  2B4S A;  4KYQ A;  3RZ2 A;  2Y2F A;  2MBC A;  3MOW A;  5A5F A;  5KA0 A;  3F9B A;  2I1Y A;  2BZL A;  3I7Z A;  1ZZW A;  2AM2 A;  1OEV A;  2B4O A;  3QCJ A;  1RPM A;  3ZM3 A;  2I75 A;  2VEY A;  4NX8 A;  1MKP A;  1NNY A;  4PYH A;  4QDI A;  3S4E A;  4GFU A;  4BUB A;  1O5Z A;  1JF7 A;  4ZIY A;  2J17 A;  2PSZ A;  2A8B A;  1OET A;  3QCF A;  2F6W A;  2BIJ A;  1KAK A;  3O4S A;  3QKP A;  3V0D A;  2F71 A;  4QUN A;  1GQQ A;  3ZM0 A;  4QBW A;  2CNG A;  2Y67 A;  1OEM X;  1U25 A;  1Q6S A;  1PXH A;  1ONY A;  3MOZ A;  2H4G A;  2I3U A;  2Y1O A;  1UAG A;  1RXD A;  3AWG A;  2F6Y A;  3V0E A;  2NT2 A;  4WU3 A;  2SHP A;  1E0D A;  4D3P A;  3EMU A;  2VEV A;  1Q6P A;  2GP0 A;  1ZCL A;  2J16 B;  1Q6N A;  2I6P A;  3S3E A;  2J16 A;  1LYV A;  3U96 A;  1OHC A;  2VEX A;  2I4G A;  3B7O A;  4HV4 A;  1FPZ A;  5K25 A;  2CNI A;  3ZM5 A;  1GWZ A;  2VTD A;  4R0T A;  1V3A A;  1G1H A;  3MMJ A;  2HVL A;  2H04 A;  5IBM A;  5K9W A;  2GCB A;  2P4D A;  2H03 A;  4YR8 B;  3QKQ A;  4TVV A;  5KA1 A;  2AHS A;  2CMC A;  2Y68 A;  1G7F A;  2GC5 A;  2R0B A;  4BJO A;  1T48 A;  1PA1 A;  2M3V A;  1GQY A;  2Y96 A;  1C88 A;  4H34 A;  5I6V A;  3BRH A;  4H1O A;  2QBP A;  4AZ1 A;  3QCB A;  2QBR A;  4QAP A;  1PA9 A;  1PYN A;  4QF5 A;  3CM3 A;  2CFV A;  1YTW A;  4KI9 A;  1FQ1 A;  1P31 A;  5KAD A;  3UAG A;  3M4U A;  5KAB A;  1P15 A;  1C86 A;  2CJZ A;  1FPR A;  3MVN A;  3ZL8 A;  2CM3 A;  4RDD A;  5KA2 A;  4WU2 A;  1T4J A;  3PS5 A;  3ZMP A;  1I9S A;  2YDU A;  2VTE A;  1FGS A;  4S0G A;  4GRZ A;  4JBC A;  3RO1 A;  5KA3 A;  2B07 A;  4JNB A;  1EEN A;  4RI5 A;  4HJP A;  4NND A;  4GE2 A;  4B04 A;  4IKC A;  5A5E A;  4ZRT A;  1BZJ A;  1YWF A;  4RKK A;  1J6U A;  2GJT A;  1PTT A;  1JLN A;  4ZI4 A;  2H4V A;  2VOR A;  5KA4 A;  4BUC A;  2UAG A;  3I36 A;  2BGE A;  2CNF A;  4PVG A;  1J4X A;  4RH5 A;  1LAR A;  3BM8 A;  1OHE A;  2QCT A;  3A5K A;  3QCG A;  1I9T A;  4OHE A;  3V0H A;  1NL9 A;  2OC3 A;  2NLK A;  1G7G A;  1AAX A;  2XPC A;  1Q6J A;  3F9A A;  3N2A A;  1YN9 A;  4OHL A;  3ZV2 A;  2OUD A;  4ICZ A;  3RGO A;  1U24 A;  3BLT A;  3EB1 A;  3OMH A;  3ZM1 A;  2G6Z A;  2QEP A;  4BPC A;  2FJN A;  1SUG A;  2ZN7 A;  4KYR A;  3SR9 A;  4HRF A;  3D1O A;  4Z6B A;  4OHH A;  5HDE A;  2B4U A;  4Y14 A;  4ERC A;  3QCI A;  1EEO A;  2ESB A;  3O3L A;  4GS0 A;  5KA9 A;  2PT0 A;  5EHR A;  1XXV A;  3QCZ A;  5J8R A;  2GWO A;  4JMJ A;  2P6X A;  2IMG A;  4R0S A;  5BX1 A;  4WTY A;  3GXG A;  2JFH A;  4OHI A;  2OOQ A;  5K23 A;  1LQF A;  1BZH A;  1PTY A;  4GE5 A;  3O4U A;  4GWF A;  2F6F A;  2I4E A;  3QCH A;  1KAV A;  2QDM A;  2WJP A;  1G1G A;  2AM1 A;  2I4H A;  1U26 A;  2WGP A;  1C84 A;  4NWG A;  2HY3 A;  5KAA A;  1OES A;  2BGD A;  3HN7 A;  4Y2E A;  4ZN5 A;  1GG4 A;  2PQ5 A;  4D3R A;  3QCK A;  3S3K A;  1P3D A;  3RGQ A;  1ONZ A;  2ZMM A;  3NME A;  3S4O A;  1YTN A;  1WCH A;  4JMK A;  1XM2 A;  5M43 A;  2Q47 A;  2NZ6 A;  5KA8 A;  2E0T A;  1BZC A;  4MBB A;  4J51 A;  2HNQ A;  1PH0 A;  1M3G A;  1PTV A;  3GXH A;  1JBV A;  1R6H A;  2CM8 A;  2WTZ A;  4QAH A;  2JFG A;  2VEU A;  2CNE A;  2HXP A;  2H4K A;  5GTJ A;  2I6I A;  2F70 A;  5K24 A;  2CNH A;  2NV5 A;  2B49 A;  3SME A;  2C7S A;  2PBN A;  2F46 A;  1X24 A;  4GRY A;  3ZM2 A;  3ZM6 A;  3QCE A;  1WAX A;  3S3H A;  2F6Z A;  2BV5 A;  3LK7 A;  1YZ4 A;  3F99 A;  3AWE A;  3F41 A;  1G1F A;  2NTA A;  3D1Q A;  4RHG A;  1L8G A;  1OEU A;  1Q6T A;  2HB1 A;  3EU0 A;  1XRI A;  3AWF A;  1W78 A;  1GFY A;  1NWE A;  3NRS A;  4GFV A;  2JJD A;  3V0F A;  2B4P A;  2I6J A;  3EZZ A;  2HC1 A;  2CMA A;  2GCA A;  2F6T A;  1XBO A;  4OHD A;  3V0G A;  2XJA A;  3A5J A;  2I42 A;  2A3K A;  3QCC A;  3D9C A;  4CVL A;  4RI4 A;  1YTS A;  1W7K A;  3ZMQ A;  2I5X A;  3O4T A;  5EHP A;  5BZZ A;  2GC6 A;  3I80 A;  1G4W R;  2PI7 A;  2Q05 A;  1C83 A; 
#chains in the Genus database with same CATH homology
 2HC2 A;  1G4U S;  2C46 A;  1QZ0 A;  1OEO X;  5LXQ B;  3S3F A;  1WRM A;  2QDC A;  4GE6 A;  3N0A A;  2H02 A;  3D42 A;  3D44 A;  1XXP A;  3QCM A;  5MMZ B;  2RF6 A;  2QBS A;  4I8N A;  1I57 A;  1NZ7 A;  1Q1M A;  1OHD A;  2I6M A;  5KA7 A;  4HJQ A;  1YPT A;  1PTU A;  1A5Y A;  5IBS A;  1C85 A;  3V0J A;  4DGP A;  4RH9 A;  2I3R A;  1NWL A;  1QXK A;  4WOH A;  2B3O A;  2VEW A;  3H2X A;  4QBE A;  4QUM A;  3V0I A;  4NYH A;  3QCN A;  1ZCK A;  3LJ8 A;  5KAC A;  1YFO A;  1ZC0 A;  1YGU A;  3OLR A;  1ECV A;  2HNP A;  1NO6 A;  2QDP A;  2QCJ A;  2FH7 A;  4YAA A;  2FJM A;  1Q6M A;  3CWE A;  2CM7 A;  5AWX A;  2PA5 A;  2AZR A;  2CM2 A;  2QBQ A;  2NT7 A;  3BLU A;  3QCD A;  4R30 A;  5K22 A;  5BZX A;  2DXP A;  1YGR A;  3O5X A;  1VHR A;  4DGX A;  3QCL A;  4NWF A;  2CMB A;  2F6V A;  2G59 A;  2HCM A;  1C87 A;  3EAX A;  5K9V A;  1D5R A;  1T49 A;  2I6O A;  3F81 A;  5BUG A;  4D3Q A;  1L8K A;  3D1H A;  2OZ5 A;  2B4S A;  4KYQ A;  3RZ2 A;  2Y2F A;  2MBC A;  3MOW A;  5KA0 A;  3F9B A;  2I1Y A;  2BZL A;  3I7Z A;  1ZZW A;  1OEV A;  2B4O A;  3QCJ A;  1RPM A;  3ZM3 A;  2I75 A;  2VEY A;  4NX8 A;  1MKP A;  1NNY A;  4PYH A;  3S4E A;  4GFU A;  1JF7 A;  2J17 A;  2PSZ A;  2A8B A;  1OET A;  3QCF A;  2F6W A;  2BIJ A;  1KAK A;  3O4S A;  3QKP A;  3V0D A;  2F71 A;  4QUN A;  3ZM0 A;  4QBW A;  2CNG A;  1OEM X;  1U25 A;  1Q6S A;  1PXH A;  1ONY A;  3MOZ A;  2H4G A;  2I3U A;  1RXD A;  3AWG A;  2F6Y A;  3V0E A;  2NT2 A;  4WU3 A;  2SHP A;  4D3P A;  3EMU A;  2VEV A;  1Q6P A;  2GP0 A;  1ZCL A;  2J16 B;  1Q6N A;  2I6P A;  3S3E A;  2J16 A;  1LYV A;  3U96 A;  1OHC A;  2VEX A;  2I4G A;  3B7O A;  1FPZ A;  5K25 A;  2CNI A;  1GWZ A;  4R0T A;  1V3A A;  1G1H A;  3MMJ A;  2HVL A;  2H04 A;  5IBM A;  5K9W A;  2P4D A;  2H03 A;  4YR8 B;  3QKQ A;  4TVV A;  5KA1 A;  2AHS A;  2CMC A;  1G7F A;  2R0B A;  4BJO A;  1T48 A;  1PA1 A;  2M3V A;  2Y96 A;  1C88 A;  4H34 A;  5I6V A;  3BRH A;  4H1O A;  2QBP A;  4AZ1 A;  3QCB A;  2QBR A;  4QAP A;  1PA9 A;  1PYN A;  3CM3 A;  2CFV A;  1YTW A;  4KI9 A;  1FQ1 A;  5KAD A;  3M4U A;  5KAB A;  1P15 A;  1C86 A;  2CJZ A;  1FPR A;  2CM3 A;  4RDD A;  5KA2 A;  4WU2 A;  1T4J A;  3PS5 A;  3ZMP A;  1I9S A;  2YDU A;  4S0G A;  4GRZ A;  4JBC A;  3RO1 A;  5KA3 A;  2B07 A;  4JNB A;  1EEN A;  4RI5 A;  4HJP A;  4NND A;  4GE2 A;  4B04 A;  4IKC A;  4ZRT A;  1BZJ A;  1YWF A;  4RKK A;  2GJT A;  1PTT A;  1JLN A;  4ZI4 A;  2H4V A;  5KA4 A;  3I36 A;  2BGE A;  2CNF A;  4PVG A;  1J4X A;  4RH5 A;  1LAR A;  3BM8 A;  1OHE A;  2QCT A;  3A5K A;  3QCG A;  1I9T A;  4OHE A;  3V0H A;  1NL9 A;  2OC3 A;  2NLK A;  1G7G A;  1AAX A;  1Q6J A;  3F9A A;  1YN9 A;  4OHL A;  3ZV2 A;  2OUD A;  4ICZ A;  3RGO A;  1U24 A;  3BLT A;  3EB1 A;  3OMH A;  3ZM1 A;  2G6Z A;  2QEP A;  4BPC A;  2FJN A;  1SUG A;  2ZN7 A;  4KYR A;  3SR9 A;  4HRF A;  3D1O A;  4Z6B A;  4OHH A;  5HDE A;  2B4U A;  4Y14 A;  4ERC A;  3QCI A;  1EEO A;  2ESB A;  3O3L A;  4GS0 A;  5KA9 A;  2PT0 A;  5EHR A;  1XXV A;  5J8R A;  2GWO A;  4JMJ A;  2P6X A;  2IMG A;  4R0S A;  5BX1 A;  4WTY A;  3GXG A;  4OHI A;  2OOQ A;  5K23 A;  1LQF A;  1BZH A;  1PTY A;  4GE5 A;  3O4U A;  4GWF A;  2F6F A;  2I4E A;  3QCH A;  1KAV A;  2QDM A;  1G1G A;  2I4H A;  1U26 A;  2WGP A;  1C84 A;  4NWG A;  2HY3 A;  5KAA A;  1OES A;  2BGD A;  4Y2E A;  4ZN5 A;  2PQ5 A;  4D3R A;  3QCK A;  3S3K A;  3RGQ A;  1ONZ A;  2ZMM A;  3NME A;  3S4O A;  1YTN A;  1WCH A;  4JMK A;  1XM2 A;  5M43 A;  2Q47 A;  2NZ6 A;  5KA8 A;  2E0T A;  1BZC A;  4MBB A;  4J51 A;  2HNQ A;  1PH0 A;  1M3G A;  1PTV A;  3GXH A;  1R6H A;  2CM8 A;  4QAH A;  2VEU A;  2CNE A;  2HXP A;  2H4K A;  5GTJ A;  2I6I A;  2F70 A;  5K24 A;  2CNH A;  2NV5 A;  2B49 A;  3SME A;  2C7S A;  2PBN A;  2F46 A;  1X24 A;  4GRY A;  3ZM2 A;  3QCE A;  1WAX A;  3S3H A;  2F6Z A;  2BV5 A;  1YZ4 A;  3F99 A;  3AWE A;  3F41 A;  1G1F A;  2NTA A;  3D1Q A;  4RHG A;  1L8G A;  1OEU A;  1Q6T A;  2HB1 A;  3EU0 A;  1XRI A;  3AWF A;  1GFY A;  1NWE A;  4GFV A;  2JJD A;  3V0F A;  2B4P A;  2I6J A;  3EZZ A;  2HC1 A;  2CMA A;  2F6T A;  1XBO A;  4OHD A;  3V0G A;  3A5J A;  2I42 A;  2A3K A;  3QCC A;  3D9C A;  4RI4 A;  1YTS A;  3ZMQ A;  2I5X A;  3O4T A;  5EHP A;  5BZZ A;  3I80 A;  1G4W R;  2PI7 A;  2Q05 A;  1C83 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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