2CNGA

Structural insights into the design of nonpeptidic isothiazolidinone- containing inhibitors of protein tyrosine phosphatase 1b
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
296
structure length
296
Chain Sequence
MEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into the Design of Nonpeptidic Isothiazolidinone-Containing Inhibitors of Protein- Tyrosine Phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
total genus 104
structure length 296
sequence length 296
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2cngA00
2B07A 4HJQA 3QCJA 3D9CA 3ZM0A 5K9VA 5EHPA 3F41A 2G6ZA 3EAXA 4JMKA 2OZ5A 2BGEA 3N0AA 2F6TA 3SR9A 2NZ6A 2OOQA 4RHGA 3OLRA 1C85A 1PXHA 2P4DA 4ZRTA 1M3GA 2NLKA 1NWLA 3QCFA 4H34A 3LJ8A 1WAXA 4JMJA 2DXPA 2YDUA 3AWEA 1YGRA 2I4GA 2HNQA 1ZCLA 5K24A 1C83A 3RGOA 1Q6JA 3CWEA 1OEVA 3QCHA 2CNHA 2RF6A 3EZZA 4WU3A 1KAKA 3QCKA 4R30A 1T48A 1QZ0A 1G1FA 2WGPA 3V0IA 3EMUA 2I6OA 5BX1A 3D1OA 2I5XA 4NWGA 1G7GA 1ECVA 1X24A 3QCIA 2CM8A 5KA3A 1YWFA 4Z6BA 4D3QA 2F6YA 3B7OA 1EEOA 4B04A 4KYQA 3RGQA 1R6HA 2VEVA 3V0HA 4OHEA 4GFUA 4TVVA 2HVLA 3SMEA 3S4OA 2FH7A 2I6IA 2I6JA 3AWFA 3GXGA 4HRFA 5LXQB 1J4XA 3QCBA 3ZM1A 2CMAA 1ZCKA 4NX8A 4GE5A 1G1GA 2HB1A 3MOWA 2ZMMA 1C87A 1OESA 3A5JA 3OMHA 2Y2FA 5M43A 3V0EA 2VEUA 4S0GA 1WCHA 3ZV2A 1U24A 5KA9A 2HC1A 2I1YA 1PTUA 4Y14A 2HNPA 1LQFA 2NTAA 1D5RA 4D3PA 2J16B 2B3OA 1Q6TA 1RPMA 2PI7A 2NT2A 2BIJA 2MBCA 3RO1A 1BZCA 1MKPA 2R0BA 5KA7A 3QCDA 4KI9A 2H4KA 4RKKA 2CJZA 1EENA 2I3UA 1AAXA 3D42A 1NL9A 2GP0A 4ICZA 1FPZA 2PT0A 3QCCA 1NNYA 4WOHA 5BZXA 2C7SA 3F9BA 5KACA 1I9TA 4NNDA 2F6FA 2IMGA 2CNIA 3NMEA 3I7ZA 3AWGA 1OEOX 3O4SA 4R0SA 3MOZA 5EHRA 1FQ1A 1YFOA 2CM2A 4OHIA 4GWFA 5KADA 3U96A 1OHDA 3QCLA 2OC3A 4DGPA 4JBCA 4GS0A 1OEMX 3CM3A 2HC2A 3A5KA 4Y2EA 5K9WA 1OHEA 1L8KA 4RH5A 4GE6A 1OETA 4RI4A 1BZHA 1KAVA 2VEXA 4R0TA 3S3EA 5KA1A 1G4US 4J51A 1Q6NA 1YPTA 1GFYA 4RI5A 1WRMA 1ZC0A 1L8GA 4QUNA 2ZN7A 3ZM2A 5J8RA 3RZ2A 2SHPA 1YN9A 3F9AA 2QBRA 3MMJA 1YTNA 4WU2A 1YGUA 2I4EA 2PSZA 5HDEA 4PYHA 1T4JA 2QBSA 2G59A 1C88A 3QCMA 2B4SA 3V0DA 3ZMPA 3D44A 3ZMQA 3QCNA 5I6VA 1ZZWA 2CM7A 2H4VA 4GE2A 2J17A 2I42A 1Q1MA 1YTWA 4QBEA 5KA8A 2H4GA 1U25A 4YR8B 2JJDA 1Q6PA 2OUDA 3O4TA 3O4UA 3V0JA 3S4EA 3O3LA 2F6WA 2QDCA 2CNFA 4JNBA 4GRYA 2H02A 2F46A 1LARA 4RDDA 1ONYA 2QCJA 2BGDA 3D1QA 1PA1A 2CM3A 3O5XA 5KABA 4QBWA 1Q6MA 2CMBA 4MBBA 3S3FA 1PTTA 2F71A 2B4UA 1YZ4A 4ZI4A 1U26A 4KYRA 2QBPA 4QAPA 2H03A 4GRZA 1VHRA 2I4HA 4OHDA 2A3KA 3ZM3A 2B4PA 2Q47A 1PH0A 2F6ZA 2P6XA 4BPCA 4OHHA 2QCTA 3QKPA 2M3VA 1JF7A 1JLNA 2CFVA 2QDPA 2E0TA 1A5YA 2F6VA 1T49A 1FPRA 5BUGA 1XXVA 1OHCA 2BZLA 1XBOA 5K23A 2CMCA 2I6MA 2FJMA 1YTSA 3BLTA 4QUMA 1GWZA 5BZZA 1PTYA 1G4WR 1PYNA 4QAHA 2VEWA 4OHLA 2I3RA 2CNEA 4D3RA 1XM2A 5IBSA 2Y96A 1C86A 2CNGA 3H2XA 5KA0A 4PVGA 3V0GA 1XRIA 4NWFA 2Q05A 2F70A 1NWEA 2QDMA 1BZJA 1I9SA 1I57A 5MMZB 1PA9A 2B49A 4HJPA 5IBMA 4ZN5A 2C46A 2I75A 2PBNA 1PTVA 2A8BA 3QCGA 2ESBA 4H1OA 4RH9A 2BV5A 3V0FA 1SUGA 4YAAA 3BRHA 1OEUA 3M4UA 1C84A 5KA4A 1LYVA 1G7FA 4NYHA 2QEPA 5K25A 2J16A 4BJOA 3I80A 5KA2A 2HY3A 2AHSA 2HCMA 2H04A 2HXPA 1P15A 3F81A 3QCEA 3F99A 3EU0A 4GFVA 1ONZA 4ERCA 1XXPA 2GWOA 1NO6A 5K22A 2B4OA 2GJTA 4AZ1A 3BM8A 3GXHA 4I8NA 4IKCA 5GTJA 2I6PA 4DGXA 3D1HA 1G1HA 1RXDA 1Q6SA 2NV5A 3QKQA 2VEYA 2NT7A 3BLUA 1V3AA 5AWXA 5KAAA 3S3HA 3I36A 2AZRA 2PQ5A 2QBQA 2PA5A 3S3KA 1NZ7A 1QXKA 3EB1A 3PS5A 4WTYA 2FJNA
chains in the Genus database with same CATH superfamily
2B07A 4HJQA 3QCJA 3D9CA 3ZM0A 5K9VA 5EHPA 3F41A 2G6ZA 3EAXA 2VOSA 4JMKA 2OZ5A 2BGEA 3N0AA 2F6TA 3SR9A 2NZ6A 4CVKA 2OOQA 2JFHA 4RHGA 3OLRA 1C85A 1PXHA 2P4DA 4ZRTA 1M3GA 2NLKA 1NWLA 1P31A 4BUCA 3QCFA 4H34A 3LJ8A 1WAXA 4JMJA 2DXPA 2YDUA 3AWEA 1YGRA 2I4GA 3HN7A 2HNQA 1ZCLA 5K24A 1C83A 3RGOA 1Q6JA 3CWEA 1OEVA 3QCHA 2CNHA 2RF6A 3EZZA 4WU3A 1KAKA 3QCKA 1E8CA 4R30A 1T48A 2JFGA 1QZ0A 1G1FA 2WGPA 3V0IA 3EMUA 2I6OA 5BX1A 3D1OA 2I5XA 4NWGA 1G7GA 1ECVA 1X24A 3QCIA 2CM8A 5KA3A 1YWFA 4Z6BA 4D3QA 2F6YA 3B7OA 1EEOA 4B04A 4KYQA 3RGQA 1R6HA 2VEVA 3V0HA 4QF5A 1E0DA 2GCBA 4OHEA 4GFUA 4TVVA 2HVLA 3SMEA 3S4OA 2FH7A 2I6IA 2I6JA 3ZM5A 3AWFA 3GXGA 4HRFA 5LXQB 1J4XA 3QCBA 3ZM1A 2CMAA 1ZCKA 4NX8A 4GE5A 1G1GA 2HB1A 3MOWA 2ZMMA 1C87A 1OESA 3A5JA 2WTZA 3OMHA 3NRSA 2Y2FA 3LK7A 5M43A 3V0EA 2VEUA 4S0GA 1WCHA 3ZV2A 1U24A 5KA9A 2HC1A 2I1YA 1PTUA 4Y14A 2HNPA 1LQFA 2NTAA 1D5RA 4BUBA 1O5ZA 4D3PA 2J16B 2B3OA 1Q6TA 1RPMA 2XPCA 2PI7A 3UAGA 2NT2A 2BIJA 2MBCA 3RO1A 1BZCA 1MKPA 2R0BA 1JBVA 5KA7A 3QCDA 4KI9A 2H4KA 4RKKA 2CJZA 1EENA 2I3UA 2Y1OA 1AAXA 1J6UA 3D42A 1NL9A 2GP0A 4ICZA 1FPZA 2PT0A 3QCCA 1NNYA 4WOHA 5BZXA 2C7SA 4HV4A 3F9BA 5KACA 1I9TA 4NNDA 2F6FA 2IMGA 2CNIA 3NMEA 3I7ZA 3AWGA 1OEOX 3O4SA 3ZM6A 4R0SA 3MOZA 5EHRA 1FQ1A 1YFOA 2CM2A 2Y67A 2VTEA 4OHIA 4GWFA 1FGSA 5KADA 3U96A 1OHDA 3QCLA 2OC3A 4DGPA 4JBCA 4GS0A 1OEMX 3CM3A 2HC2A 3A5KA 3MVNA 4Y2EA 5K9WA 1OHEA 1L8KA 4RH5A 4GE6A 1OETA 4RI4A 1BZHA 1KAVA 2VEXA 4R0TA 3S3EA 5KA1A 1GQQA 1GG4A 1G4US 4J51A 1Q6NA 1YPTA 1GFYA 4RI5A 1WRMA 1ZC0A 1L8GA 4QUNA 2ZN7A 3ZM2A 5J8RA 4C12A 3RZ2A 2VTDA 2SHPA 1YN9A 2XJAA 3F9AA 2QBRA 4CVLA 3MMJA 1YTNA 4WU2A 1EEHA 1YGUA 2I4EA 2PSZA 5HDEA 4PYHA 1T4JA 2QBSA 2G59A 1C88A 3QCMA 2B4SA 3V0DA 3ZMPA 2GC5A 4ZIYA 3D44A 3ZMQA 3QCNA 5I6VA 1ZZWA 2GCAA 2CM7A 2H4VA 4GE2A 2J17A 2I42A 1Q1MA 1YTWA 4QBEA 5KA8A 2H4GA 1U25A 4YR8B 2JJDA 1Q6PA 2OUDA 2AM1A 3O4TA 3O4UA 3V0JA 1W78A 3S4EA 4CVMA 3O3LA 2F6WA 2QDCA 2X5OA 2CNFA 4JNBA 4GRYA 2H02A 2F46A 2Y68A 1LARA 4RDDA 1ONYA 2QCJA 2BGDA 3D1QA 1PA1A 2CM3A 3O5XA 2VORA 5KABA 4QBWA 2UAGA 1Q6MA 2CMBA 4MBBA 3S3FA 1PTTA 4C13A 2F71A 2B4UA 1YZ4A 4ZI4A 1U26A 4KYRA 2QBPA 4QAPA 2H03A 2JFFA 4GRZA 2F00A 1VHRA 2I4HA 4OHDA 2A3KA 3ZM3A 2B4PA 2Q47A 1PH0A 2F6ZA 2P6XA 1UAGA 4BPCA 4OHHA 2QCTA 3QKPA 2M3VA 1JF7A 1JLNA 2CFVA 2QDPA 3QCZA 2E0TA 1A5YA 2F6VA 1T49A 1FPRA 5BUGA 1XXVA 1OHCA 2BZLA 1XBOA 5K23A 2CMCA 2I6MA 2FJMA 1YTSA 3BLTA 4QUMA 1GWZA 5BZZA 1PTYA 2Y66A 1G4WR 1PYNA 4QAHA 2VEWA 4OHLA 2I3RA 2CNEA 4D3RA 1XM2A 5IBSA 2Y96A 1W7KA 1C86A 2CNGA 3H2XA 3PYZA 5KA0A 4PVGA 3V0GA 1XRIA 4NWFA 2Q05A 2F70A 1NWEA 2QDMA 1BZJA 1I9SA 1I57A 5MMZB 1PA9A 2B49A 4HJPA 5IBMA 4ZN5A 2C46A 5A5FA 2I75A 2PBNA 1PTVA 2A8BA 2WJPA 3N2AA 3QCGA 2ESBA 4H1OA 4RH9A 2BV5A 3V0FA 1SUGA 4YAAA 3BRHA 1OEUA 1P3DA 4QDIA 3M4UA 1C84A 5KA4A 1LYVA 1G7FA 4NYHA 2QEPA 2UUPA 5K25A 2J16A 4BJOA 3I80A 5KA2A 4UAGA 2HY3A 2AHSA 2HCMA 2UUOA 2H04A 2HXPA 2GC6A 3ZL8A 1P15A 3F81A 3QCEA 3F99A 3EU0A 4GFVA 1ONZA 4ERCA 1XXPA 2GWOA 5A5EA 1NO6A 2AM2A 5K22A 2B4OA 2GJTA 4AZ1A 3BM8A 3GXHA 4I8NA 4IKCA 5GTJA 2I6PA 4DGXA 3D1HA 1G1HA 1RXDA 1Q6SA 2NV5A 3QKQA 2VEYA 2NT7A 3BLUA 1V3AA 5AWXA 5KAAA 3S3HA 1GQYA 3I36A 2AZRA 1JBWA 2PQ5A 2QBQA 2PA5A 3S3KA 1NZ7A 1QXKA 3EB1A 3PS5A 4WTYA 2FJNA
chains in the Genus database with same CATH topology
2B07A 4HJQA 3QCJA 3D9CA 3ZM0A 5K9VA 5EHPA 3F41A 2G6ZA 3EAXA 4JMKA 2OZ5A 2BGEA 3N0AA 2F6TA 3SR9A 2NZ6A 2OOQA 4RHGA 3OLRA 1C85A 1PXHA 2P4DA 4ZRTA 1M3GA 2NLKA 1NWLA 3QCFA 4H34A 3LJ8A 1WAXA 4JMJA 2DXPA 2YDUA 3AWEA 1YGRA 2I4GA 2HNQA 1ZCLA 5K24A 1C83A 3RGOA 1Q6JA 3CWEA 1OEVA 3QCHA 2CNHA 2RF6A 3EZZA 4WU3A 1KAKA 3QCKA 4R30A 1T48A 1QZ0A 1G1FA 2WGPA 3V0IA 3EMUA 2I6OA 5BX1A 3D1OA 2I5XA 4NWGA 1G7GA 1ECVA 1X24A 3QCIA 2CM8A 5KA3A 1YWFA 4Z6BA 4D3QA 2F6YA 3B7OA 1EEOA 4B04A 4KYQA 3RGQA 1R6HA 2VEVA 3V0HA 4OHEA 4GFUA 4TVVA 2HVLA 3SMEA 3S4OA 2FH7A 2I6IA 2I6JA 3AWFA 3GXGA 4HRFA 5LXQB 1J4XA 3QCBA 3ZM1A 2CMAA 1ZCKA 4NX8A 4GE5A 1G1GA 2HB1A 3MOWA 2ZMMA 1C87A 1OESA 3A5JA 3OMHA 2Y2FA 5M43A 3V0EA 2VEUA 4S0GA 1WCHA 3ZV2A 1U24A 5KA9A 2HC1A 2I1YA 1PTUA 4Y14A 2HNPA 1LQFA 2NTAA 1D5RA 4D3PA 2J16B 2B3OA 1Q6TA 1RPMA 2PI7A 2NT2A 2BIJA 2MBCA 3RO1A 1BZCA 1MKPA 2R0BA 5KA7A 3QCDA 4KI9A 2H4KA 4RKKA 2CJZA 1EENA 2I3UA 1AAXA 3D42A 1NL9A 2GP0A 4ICZA 1FPZA 2PT0A 3QCCA 1NNYA 4WOHA 5BZXA 2C7SA 3F9BA 5KACA 1I9TA 4NNDA 2F6FA 2IMGA 2CNIA 3NMEA 3I7ZA 3AWGA 1OEOX 3O4SA 4R0SA 3MOZA 5EHRA 1FQ1A 1YFOA 2CM2A 4OHIA 4GWFA 5KADA 3U96A 1OHDA 3QCLA 2OC3A 4DGPA 4JBCA 4GS0A 1OEMX 3CM3A 2HC2A 3A5KA 4Y2EA 5K9WA 1OHEA 1L8KA 4RH5A 4GE6A 1OETA 4RI4A 1BZHA 1KAVA 2VEXA 4R0TA 3S3EA 5KA1A 1G4US 4J51A 1Q6NA 1YPTA 1GFYA 4RI5A 1WRMA 1ZC0A 1L8GA 4QUNA 2ZN7A 3ZM2A 5J8RA 3RZ2A 2SHPA 1YN9A 3F9AA 2QBRA 3MMJA 1YTNA 4WU2A 1YGUA 2I4EA 2PSZA 5HDEA 4PYHA 1T4JA 2QBSA 2G59A 1C88A 3QCMA 2B4SA 3V0DA 3ZMPA 3D44A 3ZMQA 3QCNA 5I6VA 1ZZWA 2CM7A 2H4VA 4GE2A 2J17A 2I42A 1Q1MA 1YTWA 4QBEA 5KA8A 2H4GA 1U25A 4YR8B 2JJDA 1Q6PA 2OUDA 3O4TA 3O4UA 3V0JA 3S4EA 3O3LA 2F6WA 2QDCA 2CNFA 4JNBA 4GRYA 2H02A 2F46A 1LARA 4RDDA 1ONYA 2QCJA 2BGDA 3D1QA 1PA1A 2CM3A 3O5XA 5KABA 4QBWA 1Q6MA 2CMBA 4MBBA 3S3FA 1PTTA 2F71A 2B4UA 1YZ4A 4ZI4A 1U26A 4KYRA 2QBPA 4QAPA 2H03A 4GRZA 1VHRA 2I4HA 4OHDA 2A3KA 3ZM3A 2B4PA 2Q47A 1PH0A 2F6ZA 2P6XA 4BPCA 4OHHA 2QCTA 3QKPA 2M3VA 1JF7A 1JLNA 2CFVA 2QDPA 2E0TA 1A5YA 2F6VA 1T49A 1FPRA 5BUGA 1XXVA 1OHCA 2BZLA 1XBOA 5K23A 2CMCA 2I6MA 2FJMA 1YTSA 3BLTA 4QUMA 1GWZA 5BZZA 1PTYA 1G4WR 1PYNA 4QAHA 2VEWA 4OHLA 2I3RA 2CNEA 4D3RA 1XM2A 5IBSA 2Y96A 1C86A 2CNGA 3H2XA 5KA0A 4PVGA 3V0GA 1XRIA 4NWFA 2Q05A 2F70A 1NWEA 2QDMA 1BZJA 1I9SA 1I57A 5MMZB 1PA9A 2B49A 4HJPA 5IBMA 4ZN5A 2C46A 2I75A 2PBNA 1PTVA 2A8BA 3QCGA 2ESBA 4H1OA 4RH9A 2BV5A 3V0FA 1SUGA 4YAAA 3BRHA 1OEUA 3M4UA 1C84A 5KA4A 1LYVA 1G7FA 4NYHA 2QEPA 5K25A 2J16A 4BJOA 3I80A 5KA2A 2HY3A 2AHSA 2HCMA 2H04A 2HXPA 1P15A 3F81A 3QCEA 3F99A 3EU0A 4GFVA 1ONZA 4ERCA 1XXPA 2GWOA 1NO6A 5K22A 2B4OA 2GJTA 4AZ1A 3BM8A 3GXHA 4I8NA 4IKCA 5GTJA 2I6PA 4DGXA 3D1HA 1G1HA 1RXDA 1Q6SA 2NV5A 3QKQA 2VEYA 2NT7A 3BLUA 1V3AA 5AWXA 5KAAA 3S3HA 3I36A 2AZRA 2PQ5A 2QBQA 2PA5A 3S3KA 1NZ7A 1QXKA 3EB1A 3PS5A 4WTYA 2FJNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B07 A;  4HJQ A;  3QCJ A;  3D9C A;  3ZM0 A;  5K9V A;  5EHP A;  3F41 A;  2G6Z A;  3EAX A;  4JMK A;  2OZ5 A;  2BGE A;  3N0A A;  2F6T A;  3SR9 A;  2NZ6 A;  2OOQ A;  4RHG A;  3OLR A;  1C85 A;  1PXH A;  2P4D A;  4ZRT A;  1M3G A;  2NLK A;  1NWL A;  3QCF A;  4H34 A;  3LJ8 A;  1WAX A;  4JMJ A;  2DXP A;  2YDU A;  3AWE A;  1YGR A;  2I4G A;  2HNQ A;  1ZCL A;  5K24 A;  1C83 A;  3RGO A;  1Q6J A;  3CWE A;  1OEV A;  3QCH A;  2CNH A;  2RF6 A;  3EZZ A;  4WU3 A;  1KAK A;  3QCK A;  4R30 A;  1T48 A;  1QZ0 A;  1G1F A;  2WGP A;  3V0I A;  3EMU A;  2I6O A;  5BX1 A;  3D1O A;  2I5X A;  4NWG A;  1G7G A;  1ECV A;  1X24 A;  3QCI A;  2CM8 A;  5KA3 A;  1YWF A;  4Z6B A;  4D3Q A;  2F6Y A;  3B7O A;  1EEO A;  4B04 A;  4KYQ A;  3RGQ A;  1R6H A;  2VEV A;  3V0H A;  4OHE A;  4GFU A;  4TVV A;  2HVL A;  3SME A;  3S4O A;  2FH7 A;  2I6I A;  2I6J A;  3AWF A;  3GXG A;  4HRF A;  5LXQ B;  1J4X A;  3QCB A;  3ZM1 A;  2CMA A;  1ZCK A;  4NX8 A;  4GE5 A;  1G1G A;  2HB1 A;  3MOW A;  2ZMM A;  1C87 A;  1OES A;  3A5J A;  3OMH A;  2Y2F A;  5M43 A;  3V0E A;  2VEU A;  4S0G A;  1WCH A;  3ZV2 A;  1U24 A;  5KA9 A;  2HC1 A;  2I1Y A;  1PTU A;  4Y14 A;  2HNP A;  1LQF A;  2NTA A;  1D5R A;  4D3P A;  2J16 B;  2B3O A;  1Q6T A;  1RPM A;  2PI7 A;  2NT2 A;  2BIJ A;  2MBC A;  3RO1 A;  1BZC A;  1MKP A;  2R0B A;  5KA7 A;  3QCD A;  4KI9 A;  2H4K A;  4RKK A;  2CJZ A;  1EEN A;  2I3U A;  1AAX A;  3D42 A;  1NL9 A;  2GP0 A;  4ICZ A;  1FPZ A;  2PT0 A;  3QCC A;  1NNY A;  4WOH A;  5BZX A;  2C7S A;  3F9B A;  5KAC A;  1I9T A;  4NND A;  2F6F A;  2IMG A;  2CNI A;  3NME A;  3I7Z A;  3AWG A;  1OEO X;  3O4S A;  4R0S A;  3MOZ A;  5EHR A;  1FQ1 A;  1YFO A;  2CM2 A;  4OHI A;  4GWF A;  5KAD A;  3U96 A;  1OHD A;  3QCL A;  2OC3 A;  4DGP A;  4JBC A;  4GS0 A;  1OEM X;  3CM3 A;  2HC2 A;  3A5K A;  4Y2E A;  5K9W A;  1OHE A;  1L8K A;  4RH5 A;  4GE6 A;  1OET A;  4RI4 A;  1BZH A;  1KAV A;  2VEX A;  4R0T A;  3S3E A;  5KA1 A;  1G4U S;  4J51 A;  1Q6N A;  1YPT A;  1GFY A;  4RI5 A;  1WRM A;  1ZC0 A;  1L8G A;  4QUN A;  2ZN7 A;  3ZM2 A;  5J8R A;  3RZ2 A;  2SHP A;  1YN9 A;  3F9A A;  2QBR A;  3MMJ A;  1YTN A;  4WU2 A;  1YGU A;  2I4E A;  2PSZ A;  5HDE A;  4PYH A;  1T4J A;  2QBS A;  2G59 A;  1C88 A;  3QCM A;  2B4S A;  3V0D A;  3ZMP A;  3D44 A;  3ZMQ A;  3QCN A;  5I6V A;  1ZZW A;  2CM7 A;  2H4V A;  4GE2 A;  2J17 A;  2I42 A;  1Q1M A;  1YTW A;  4QBE A;  5KA8 A;  2H4G A;  1U25 A;  4YR8 B;  2JJD A;  1Q6P A;  2OUD A;  3O4T A;  3O4U A;  3V0J A;  3S4E A;  3O3L A;  2F6W A;  2QDC A;  2CNF A;  4JNB A;  4GRY A;  2H02 A;  2F46 A;  1LAR A;  4RDD A;  1ONY A;  2QCJ A;  2BGD A;  3D1Q A;  1PA1 A;  2CM3 A;  3O5X A;  5KAB A;  4QBW A;  1Q6M A;  2CMB A;  4MBB A;  3S3F A;  1PTT A;  2F71 A;  2B4U A;  1YZ4 A;  4ZI4 A;  1U26 A;  4KYR A;  2QBP A;  4QAP A;  2H03 A;  4GRZ A;  1VHR A;  2I4H A;  4OHD A;  2A3K A;  3ZM3 A;  2B4P A;  2Q47 A;  1PH0 A;  2F6Z A;  2P6X A;  4BPC A;  4OHH A;  2QCT A;  3QKP A;  2M3V A;  1JF7 A;  1JLN A;  2CFV A;  2QDP A;  2E0T A;  1A5Y A;  2F6V A;  1T49 A;  1FPR A;  5BUG A;  1XXV A;  1OHC A;  2BZL A;  1XBO A;  5K23 A;  2CMC A;  2I6M A;  2FJM A;  1YTS A;  3BLT A;  4QUM A;  1GWZ A;  5BZZ A;  1PTY A;  1G4W R;  1PYN A;  4QAH A;  2VEW A;  4OHL A;  2I3R A;  2CNE A;  4D3R A;  1XM2 A;  5IBS A;  2Y96 A;  1C86 A;  2CNG A;  3H2X A;  5KA0 A;  4PVG A;  3V0G A;  1XRI A;  4NWF A;  2Q05 A;  2F70 A;  1NWE A;  2QDM A;  1BZJ A;  1I9S A;  1I57 A;  5MMZ B;  1PA9 A;  2B49 A;  4HJP A;  5IBM A;  4ZN5 A;  2C46 A;  2I75 A;  2PBN A;  1PTV A;  2A8B A;  3QCG A;  2ESB A;  4H1O A;  4RH9 A;  2BV5 A;  3V0F A;  1SUG A;  4YAA A;  3BRH A;  1OEU A;  3M4U A;  1C84 A;  5KA4 A;  1LYV A;  1G7F A;  4NYH A;  2QEP A;  5K25 A;  2J16 A;  4BJO A;  3I80 A;  5KA2 A;  2HY3 A;  2AHS A;  2HCM A;  2H04 A;  2HXP A;  1P15 A;  3F81 A;  3QCE A;  3F99 A;  3EU0 A;  4GFV A;  1ONZ A;  4ERC A;  1XXP A;  2GWO A;  1NO6 A;  5K22 A;  2B4O A;  2GJT A;  4AZ1 A;  3BM8 A;  3GXH A;  4I8N A;  4IKC A;  5GTJ A;  2I6P A;  4DGX A;  3D1H A;  1G1H A;  1RXD A;  1Q6S A;  2NV5 A;  3QKQ A;  2VEY A;  2NT7 A;  3BLU A;  1V3A A;  5AWX A;  5KAA A;  3S3H A;  3I36 A;  2AZR A;  2PQ5 A;  2QBQ A;  2PA5 A;  3S3K A;  1NZ7 A;  1QXK A;  3EB1 A;  3PS5 A;  4WTY A;  2FJN A; 
#chains in the Genus database with same CATH topology
 2B07 A;  4HJQ A;  3QCJ A;  3D9C A;  3ZM0 A;  5K9V A;  5EHP A;  3F41 A;  2G6Z A;  3EAX A;  2VOS A;  4JMK A;  2OZ5 A;  2BGE A;  3N0A A;  2F6T A;  3SR9 A;  2NZ6 A;  4CVK A;  2OOQ A;  2JFH A;  4RHG A;  3OLR A;  1C85 A;  1PXH A;  2P4D A;  4ZRT A;  1M3G A;  2NLK A;  1NWL A;  1P31 A;  4BUC A;  3QCF A;  4H34 A;  3LJ8 A;  1WAX A;  4JMJ A;  2DXP A;  2YDU A;  3AWE A;  1YGR A;  2I4G A;  3HN7 A;  2HNQ A;  1ZCL A;  5K24 A;  1C83 A;  3RGO A;  1Q6J A;  3CWE A;  1OEV A;  3QCH A;  2CNH A;  2RF6 A;  3EZZ A;  4WU3 A;  1KAK A;  3QCK A;  1E8C A;  4R30 A;  1T48 A;  2JFG A;  1QZ0 A;  1G1F A;  2WGP A;  3V0I A;  3EMU A;  2I6O A;  5BX1 A;  3D1O A;  2I5X A;  4NWG A;  1G7G A;  1ECV A;  1X24 A;  3QCI A;  2CM8 A;  5KA3 A;  1YWF A;  4Z6B A;  4D3Q A;  2F6Y A;  3B7O A;  1EEO A;  4B04 A;  4KYQ A;  3RGQ A;  1R6H A;  2VEV A;  3V0H A;  4QF5 A;  1E0D A;  2GCB A;  4OHE A;  4GFU A;  4TVV A;  2HVL A;  3SME A;  3S4O A;  2FH7 A;  2I6I A;  2I6J A;  3ZM5 A;  3AWF A;  3GXG A;  4HRF A;  5LXQ B;  1J4X A;  3QCB A;  3ZM1 A;  2CMA A;  1ZCK A;  4NX8 A;  4GE5 A;  1G1G A;  2HB1 A;  3MOW A;  2ZMM A;  1C87 A;  1OES A;  3A5J A;  2WTZ A;  3OMH A;  3NRS A;  2Y2F A;  3LK7 A;  5M43 A;  3V0E A;  2VEU A;  4S0G A;  1WCH A;  3ZV2 A;  1U24 A;  5KA9 A;  2HC1 A;  2I1Y A;  1PTU A;  4Y14 A;  2HNP A;  1LQF A;  2NTA A;  1D5R A;  4BUB A;  1O5Z A;  4D3P A;  2J16 B;  2B3O A;  1Q6T A;  1RPM A;  2XPC A;  2PI7 A;  3UAG A;  2NT2 A;  2BIJ A;  2MBC A;  3RO1 A;  1BZC A;  1MKP A;  2R0B A;  1JBV A;  5KA7 A;  3QCD A;  4KI9 A;  2H4K A;  4RKK A;  2CJZ A;  1EEN A;  2I3U A;  2Y1O A;  1AAX A;  1J6U A;  3D42 A;  1NL9 A;  2GP0 A;  4ICZ A;  1FPZ A;  2PT0 A;  3QCC A;  1NNY A;  4WOH A;  5BZX A;  2C7S A;  4HV4 A;  3F9B A;  5KAC A;  1I9T A;  4NND A;  2F6F A;  2IMG A;  2CNI A;  3NME A;  3I7Z A;  3AWG A;  1OEO X;  3O4S A;  3ZM6 A;  4R0S A;  3MOZ A;  5EHR A;  1FQ1 A;  1YFO A;  2CM2 A;  2Y67 A;  2VTE A;  4OHI A;  4GWF A;  1FGS A;  5KAD A;  3U96 A;  1OHD A;  3QCL A;  2OC3 A;  4DGP A;  4JBC A;  4GS0 A;  1OEM X;  3CM3 A;  2HC2 A;  3A5K A;  3MVN A;  4Y2E A;  5K9W A;  1OHE A;  1L8K A;  4RH5 A;  4GE6 A;  1OET A;  4RI4 A;  1BZH A;  1KAV A;  2VEX A;  4R0T A;  3S3E A;  5KA1 A;  1GQQ A;  1GG4 A;  1G4U S;  4J51 A;  1Q6N A;  1YPT A;  1GFY A;  4RI5 A;  1WRM A;  1ZC0 A;  1L8G A;  4QUN A;  2ZN7 A;  3ZM2 A;  5J8R A;  4C12 A;  3RZ2 A;  2VTD A;  2SHP A;  1YN9 A;  2XJA A;  3F9A A;  2QBR A;  4CVL A;  3MMJ A;  1YTN A;  4WU2 A;  1EEH A;  1YGU A;  2I4E A;  2PSZ A;  5HDE A;  4PYH A;  1T4J A;  2QBS A;  2G59 A;  1C88 A;  3QCM A;  2B4S A;  3V0D A;  3ZMP A;  2GC5 A;  4ZIY A;  3D44 A;  3ZMQ A;  3QCN A;  5I6V A;  1ZZW A;  2GCA A;  2CM7 A;  2H4V A;  4GE2 A;  2J17 A;  2I42 A;  1Q1M A;  1YTW A;  4QBE A;  5KA8 A;  2H4G A;  1U25 A;  4YR8 B;  2JJD A;  1Q6P A;  2OUD A;  2AM1 A;  3O4T A;  3O4U A;  3V0J A;  1W78 A;  3S4E A;  4CVM A;  3O3L A;  2F6W A;  2QDC A;  2X5O A;  2CNF A;  4JNB A;  4GRY A;  2H02 A;  2F46 A;  2Y68 A;  1LAR A;  4RDD A;  1ONY A;  2QCJ A;  2BGD A;  3D1Q A;  1PA1 A;  2CM3 A;  3O5X A;  2VOR A;  5KAB A;  4QBW A;  2UAG A;  1Q6M A;  2CMB A;  4MBB A;  3S3F A;  1PTT A;  4C13 A;  2F71 A;  2B4U A;  1YZ4 A;  4ZI4 A;  1U26 A;  4KYR A;  2QBP A;  4QAP A;  2H03 A;  2JFF A;  4GRZ A;  2F00 A;  1VHR A;  2I4H A;  4OHD A;  2A3K A;  3ZM3 A;  2B4P A;  2Q47 A;  1PH0 A;  2F6Z A;  2P6X A;  1UAG A;  4BPC A;  4OHH A;  2QCT A;  3QKP A;  2M3V A;  1JF7 A;  1JLN A;  2CFV A;  2QDP A;  3QCZ A;  2E0T A;  1A5Y A;  2F6V A;  1T49 A;  1FPR A;  5BUG A;  1XXV A;  1OHC A;  2BZL A;  1XBO A;  5K23 A;  2CMC A;  2I6M A;  2FJM A;  1YTS A;  3BLT A;  4QUM A;  1GWZ A;  5BZZ A;  1PTY A;  2Y66 A;  1G4W R;  1PYN A;  4QAH A;  2VEW A;  4OHL A;  2I3R A;  2CNE A;  4D3R A;  1XM2 A;  5IBS A;  2Y96 A;  1W7K A;  1C86 A;  2CNG A;  3H2X A;  3PYZ A;  5KA0 A;  4PVG A;  3V0G A;  1XRI A;  4NWF A;  2Q05 A;  2F70 A;  1NWE A;  2QDM A;  1BZJ A;  1I9S A;  1I57 A;  5MMZ B;  1PA9 A;  2B49 A;  4HJP A;  5IBM A;  4ZN5 A;  2C46 A;  5A5F A;  2I75 A;  2PBN A;  1PTV A;  2A8B A;  2WJP A;  3N2A A;  3QCG A;  2ESB A;  4H1O A;  4RH9 A;  2BV5 A;  3V0F A;  1SUG A;  4YAA A;  3BRH A;  1OEU A;  1P3D A;  4QDI A;  3M4U A;  1C84 A;  5KA4 A;  1LYV A;  1G7F A;  4NYH A;  2QEP A;  2UUP A;  5K25 A;  2J16 A;  4BJO A;  3I80 A;  5KA2 A;  4UAG A;  2HY3 A;  2AHS A;  2HCM A;  2UUO A;  2H04 A;  2HXP A;  2GC6 A;  3ZL8 A;  1P15 A;  3F81 A;  3QCE A;  3F99 A;  3EU0 A;  4GFV A;  1ONZ A;  4ERC A;  1XXP A;  2GWO A;  5A5E A;  1NO6 A;  2AM2 A;  5K22 A;  2B4O A;  2GJT A;  4AZ1 A;  3BM8 A;  3GXH A;  4I8N A;  4IKC A;  5GTJ A;  2I6P A;  4DGX A;  3D1H A;  1G1H A;  1RXD A;  1Q6S A;  2NV5 A;  3QKQ A;  2VEY A;  2NT7 A;  3BLU A;  1V3A A;  5AWX A;  5KAA A;  3S3H A;  1GQY A;  3I36 A;  2AZR A;  1JBW A;  2PQ5 A;  2QBQ A;  2PA5 A;  3S3K A;  1NZ7 A;  1QXK A;  3EB1 A;  3PS5 A;  4WTY A;  2FJN A; 
#chains in the Genus database with same CATH homology
 2B07 A;  4HJQ A;  3QCJ A;  3D9C A;  3ZM0 A;  5K9V A;  5EHP A;  3F41 A;  2G6Z A;  3EAX A;  4JMK A;  2OZ5 A;  2BGE A;  3N0A A;  2F6T A;  3SR9 A;  2NZ6 A;  2OOQ A;  4RHG A;  3OLR A;  1C85 A;  1PXH A;  2P4D A;  4ZRT A;  1M3G A;  2NLK A;  1NWL A;  3QCF A;  4H34 A;  3LJ8 A;  1WAX A;  4JMJ A;  2DXP A;  2YDU A;  3AWE A;  1YGR A;  2I4G A;  2HNQ A;  1ZCL A;  5K24 A;  1C83 A;  3RGO A;  1Q6J A;  3CWE A;  1OEV A;  3QCH A;  2CNH A;  2RF6 A;  3EZZ A;  4WU3 A;  1KAK A;  3QCK A;  4R30 A;  1T48 A;  1QZ0 A;  1G1F A;  2WGP A;  3V0I A;  3EMU A;  2I6O A;  5BX1 A;  3D1O A;  2I5X A;  4NWG A;  1G7G A;  1ECV A;  1X24 A;  3QCI A;  2CM8 A;  5KA3 A;  1YWF A;  4Z6B A;  4D3Q A;  2F6Y A;  3B7O A;  1EEO A;  4B04 A;  4KYQ A;  3RGQ A;  1R6H A;  2VEV A;  3V0H A;  4OHE A;  4GFU A;  4TVV A;  2HVL A;  3SME A;  3S4O A;  2FH7 A;  2I6I A;  2I6J A;  3AWF A;  3GXG A;  4HRF A;  5LXQ B;  1J4X A;  3QCB A;  3ZM1 A;  2CMA A;  1ZCK A;  4NX8 A;  4GE5 A;  1G1G A;  2HB1 A;  3MOW A;  2ZMM A;  1C87 A;  1OES A;  3A5J A;  3OMH A;  2Y2F A;  5M43 A;  3V0E A;  2VEU A;  4S0G A;  1WCH A;  3ZV2 A;  1U24 A;  5KA9 A;  2HC1 A;  2I1Y A;  1PTU A;  4Y14 A;  2HNP A;  1LQF A;  2NTA A;  1D5R A;  4D3P A;  2J16 B;  2B3O A;  1Q6T A;  1RPM A;  2PI7 A;  2NT2 A;  2BIJ A;  2MBC A;  3RO1 A;  1BZC A;  1MKP A;  2R0B A;  5KA7 A;  3QCD A;  4KI9 A;  2H4K A;  4RKK A;  2CJZ A;  1EEN A;  2I3U A;  1AAX A;  3D42 A;  1NL9 A;  2GP0 A;  4ICZ A;  1FPZ A;  2PT0 A;  3QCC A;  1NNY A;  4WOH A;  5BZX A;  2C7S A;  3F9B A;  5KAC A;  1I9T A;  4NND A;  2F6F A;  2IMG A;  2CNI A;  3NME A;  3I7Z A;  3AWG A;  1OEO X;  3O4S A;  4R0S A;  3MOZ A;  5EHR A;  1FQ1 A;  1YFO A;  2CM2 A;  4OHI A;  4GWF A;  5KAD A;  3U96 A;  1OHD A;  3QCL A;  2OC3 A;  4DGP A;  4JBC A;  4GS0 A;  1OEM X;  3CM3 A;  2HC2 A;  3A5K A;  4Y2E A;  5K9W A;  1OHE A;  1L8K A;  4RH5 A;  4GE6 A;  1OET A;  4RI4 A;  1BZH A;  1KAV A;  2VEX A;  4R0T A;  3S3E A;  5KA1 A;  1G4U S;  4J51 A;  1Q6N A;  1YPT A;  1GFY A;  4RI5 A;  1WRM A;  1ZC0 A;  1L8G A;  4QUN A;  2ZN7 A;  3ZM2 A;  5J8R A;  3RZ2 A;  2SHP A;  1YN9 A;  3F9A A;  2QBR A;  3MMJ A;  1YTN A;  4WU2 A;  1YGU A;  2I4E A;  2PSZ A;  5HDE A;  4PYH A;  1T4J A;  2QBS A;  2G59 A;  1C88 A;  3QCM A;  2B4S A;  3V0D A;  3ZMP A;  3D44 A;  3ZMQ A;  3QCN A;  5I6V A;  1ZZW A;  2CM7 A;  2H4V A;  4GE2 A;  2J17 A;  2I42 A;  1Q1M A;  1YTW A;  4QBE A;  5KA8 A;  2H4G A;  1U25 A;  4YR8 B;  2JJD A;  1Q6P A;  2OUD A;  3O4T A;  3O4U A;  3V0J A;  3S4E A;  3O3L A;  2F6W A;  2QDC A;  2CNF A;  4JNB A;  4GRY A;  2H02 A;  2F46 A;  1LAR A;  4RDD A;  1ONY A;  2QCJ A;  2BGD A;  3D1Q A;  1PA1 A;  2CM3 A;  3O5X A;  5KAB A;  4QBW A;  1Q6M A;  2CMB A;  4MBB A;  3S3F A;  1PTT A;  2F71 A;  2B4U A;  1YZ4 A;  4ZI4 A;  1U26 A;  4KYR A;  2QBP A;  4QAP A;  2H03 A;  4GRZ A;  1VHR A;  2I4H A;  4OHD A;  2A3K A;  3ZM3 A;  2B4P A;  2Q47 A;  1PH0 A;  2F6Z A;  2P6X A;  4BPC A;  4OHH A;  2QCT A;  3QKP A;  2M3V A;  1JF7 A;  1JLN A;  2CFV A;  2QDP A;  2E0T A;  1A5Y A;  2F6V A;  1T49 A;  1FPR A;  5BUG A;  1XXV A;  1OHC A;  2BZL A;  1XBO A;  5K23 A;  2CMC A;  2I6M A;  2FJM A;  1YTS A;  3BLT A;  4QUM A;  1GWZ A;  5BZZ A;  1PTY A;  1G4W R;  1PYN A;  4QAH A;  2VEW A;  4OHL A;  2I3R A;  2CNE A;  4D3R A;  1XM2 A;  5IBS A;  2Y96 A;  1C86 A;  2CNG A;  3H2X A;  5KA0 A;  4PVG A;  3V0G A;  1XRI A;  4NWF A;  2Q05 A;  2F70 A;  1NWE A;  2QDM A;  1BZJ A;  1I9S A;  1I57 A;  5MMZ B;  1PA9 A;  2B49 A;  4HJP A;  5IBM A;  4ZN5 A;  2C46 A;  2I75 A;  2PBN A;  1PTV A;  2A8B A;  3QCG A;  2ESB A;  4H1O A;  4RH9 A;  2BV5 A;  3V0F A;  1SUG A;  4YAA A;  3BRH A;  1OEU A;  3M4U A;  1C84 A;  5KA4 A;  1LYV A;  1G7F A;  4NYH A;  2QEP A;  5K25 A;  2J16 A;  4BJO A;  3I80 A;  5KA2 A;  2HY3 A;  2AHS A;  2HCM A;  2H04 A;  2HXP A;  1P15 A;  3F81 A;  3QCE A;  3F99 A;  3EU0 A;  4GFV A;  1ONZ A;  4ERC A;  1XXP A;  2GWO A;  1NO6 A;  5K22 A;  2B4O A;  2GJT A;  4AZ1 A;  3BM8 A;  3GXH A;  4I8N A;  4IKC A;  5GTJ A;  2I6P A;  4DGX A;  3D1H A;  1G1H A;  1RXD A;  1Q6S A;  2NV5 A;  3QKQ A;  2VEY A;  2NT7 A;  3BLU A;  1V3A A;  5AWX A;  5KAA A;  3S3H A;  3I36 A;  2AZR A;  2PQ5 A;  2QBQ A;  2PA5 A;  3S3K A;  1NZ7 A;  1QXK A;  3EB1 A;  3PS5 A;  4WTY A;  2FJN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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