4QAPA

The second sphere residue t263 is important for function and activity of ptp1b through modulating wpd loop
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
299
structure length
299
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQNADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop
pubmed doi rcsb
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
molecule tags Hydrolase
source organism Homo sapiens
total genus 104
structure length 299
sequence length 299
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2014-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4qapA00
1BZCA 1ZCKA 2CNGA 4RH5A 5KACA 2PI7A 2B3OA 4QAHA 1C86A 1ONYA 2GWOA 5BX1A 3D1HA 3OLRA 4KYQA 1OETA 2QEPA 2J17A 5M43A 2NT7A 5KA9A 3QCHA 2BV5A 3SMEA 4MBBA 4RKKA 1Q6PA 4WU2A 4TVVA 5KA8A 2QBSA 1G4US 1NNYA 3F9AA 5EHRA 2F6FA 1C83A 2CMCA 2I6IA 4JNBA 2OC3A 2QBPA 1WRMA 2I5XA 4JMKA 5KA3A 5KAAA 2VEWA 3RO1A 4KYRA 3ZM0A 2H4KA 4ZI4A 2M3VA 4GE5A 4I8NA 3O5XA 4HJQA 4OHDA 3A5KA 3RZ2A 3V0FA 3CM3A 1LQFA 1WCHA 2I4HA 3D1OA 3EMUA 2B49A 2CM3A 4HJPA 2F6TA 2IMGA 4PYHA 3I36A 1G7GA 1OEUA 4PVGA 1X24A 3QKQA 5KA2A 1PTTA 3D1QA 2ZN7A 2A8BA 3QCFA 1QXKA 3QCJA 4ICZA 2C7SA 1G1GA 2F6YA 2I6OA 2A3KA 2E0TA 3RGQA 4OHIA 2I6MA 1G4WR 4Y14A 3AWGA 5AWXA 2H02A 1YTSA 2B07A 4GFVA 3SR9A 1JF7A 1ONZA 4GFUA 3PS5A 3S3KA 1OHEA 2GP0A 3QCKA 4BPCA 4NNDA 3OMHA 2VEYA 1OEMX 4IKCA 1D5RA 1G7FA 3NMEA 4NWFA 5GTJA 1PXHA 2NLKA 1Q6MA 2QCJA 1YTWA 3EAXA 3U96A 1OEOX 4NYHA 4QAPA 4D3PA 2FJNA 1SUGA 2I4GA 2F46A 5BUGA 1G1FA 3BLUA 4JMJA 3BRHA 2F71A 4DGXA 3EB1A 1C85A 2RF6A 2HNPA 3F99A 2I75A 2QDPA 4GE2A 2H03A 4GWFA 2R0BA 2B4OA 1PTUA 4GE6A 2CNFA 5KA7A 3V0DA 4RDDA 1U25A 1C88A 3V0IA 4OHEA 3QCLA 3AWFA 2F6WA 5K25A 1YWFA 1I57A 2CM2A 2J16B 2QBRA 5BZZA 1Q6TA 2FJMA 4D3QA 3ZV2A 1Q1MA 4J51A 2HVLA 3A5JA 3S3HA 3S4OA 5KADA 2NTAA 2PQ5A 2MBCA 3ZM2A 3QKPA 3MOWA 1Q6NA 1Q6JA 5LXQB 1OHDA 3QCCA 1WAXA 2JJDA 4WTYA 4QBEA 3QCDA 2HCMA 1YGRA 2I1YA 3QCEA 2OZ5A 2CJZA 3H2XA 3V0HA 2I3UA 1LYVA 1XM2A 4DGPA 3QCGA 3GXGA 1RPMA 2QBQA 3QCMA 2ZMMA 1Q6SA 2I6PA 3O3LA 1OESA 2P6XA 2NV5A 5EHPA 1YTNA 3QCIA 5IBSA 1C87A 1NWEA 2WGPA 2BZLA 1KAKA 2NZ6A 1YPTA 2Y96A 3BM8A 4KI9A 1BZJA 3GXHA 4YAAA 1OEVA 1RXDA 1XXVA 1NO6A 1EEOA 5KA0A 2HY3A 3QCNA 2H4VA 4ERCA 3V0JA 1M3GA 1KAVA 2F6ZA 4Z6BA 5KA4A 2NT2A 2Y2FA 5I6VA 2C46A 2CNHA 3N0AA 4QUMA 2F6VA 1EENA 3D9CA 2BIJA 1C84A 1V3AA 2CFVA 2F70A 1L8KA 3O4TA 1YZ4A 2SHPA 2G59A 1PTVA 1PTYA 2QDCA 4GRYA 2AHSA 3O4UA 1NWLA 1PA1A 3AWEA 1XBOA 4YR8B 1JLNA 4S0GA 1GFYA 3QCBA 2PA5A 1P15A 1YFOA 1AAXA 1QZ0A 5K22A 4RI4A 3B7OA 3V0EA 1FQ1A 1R6HA 1ECVA 1FPRA 2B4SA 2B4UA 4R0TA 2GJTA 1PH0A 1XRIA 2VEVA 2H4GA 4Y2EA 1I9SA 1XXPA 5IBMA 1YGUA 1BZHA 1J4XA 1FPZA 2H04A 3LJ8A 1YN9A 2FH7A 2I3RA 5K23A 3O4SA 2I42A 2HXPA 4ZN5A 3S3EA 3RGOA 2BGEA 2CMAA 2CM8A 2I4EA 4QUNA 3MOZA 1ZCLA 4ZRTA 2P4DA 1GWZA 3F9BA 4OHLA 5BZXA 1PYNA 2QCTA 4RH9A 2CM7A 3D44A 1MKPA 5J8RA 2AZRA 2I6JA 2PT0A 4AZ1A 4NX8A 4GRZA 1A5YA 2G6ZA 1ZC0A 4RI5A 3D42A 3EU0A 2VEUA 2OOQA 5HDEA 5K9WA 2YDUA 4H34A 4GS0A 3ZM3A 1ZZWA 5MMZB 5KA1A 4H1OA 4WOHA 4BJOA 3F41A 2HC1A 2CNEA 2DXPA 4HRFA 4D3RA 3S3FA 2PBNA 1NL9A 3I7ZA 5K9VA 2Q05A 3M4UA 2QDMA 2CNIA 5K24A 2CMBA 2PSZA 4R0SA 1T48A 3ZMPA 4B04A 2BGDA 3BLTA 2ESBA 1T49A 3V0GA 2HNQA 4QBWA 1T4JA 3CWEA 1NZ7A 2B4PA 2HB1A 1L8GA 1VHRA 4WU3A 3ZMQA 3MMJA 4OHHA 3ZM1A 4JBCA 2J16A 2OUDA 2HC2A 1I9TA 1OHCA 1PA9A 2Q47A 1LARA 4R30A 4NWGA 1U24A 1U26A 3S4EA 3I80A 2VEXA 3EZZA 4RHGA 1G1HA 3F81A 5KABA
chains in the Genus database with same CATH superfamily
1BZCA 1ZCKA 2CNGA 4RH5A 5KACA 2PI7A 2B3OA 4QAHA 1C86A 1ONYA 2GWOA 5BX1A 3D1HA 3OLRA 4KYQA 1OETA 2QEPA 4ZIYA 2J17A 5M43A 2NT7A 5KA9A 3QCHA 2BV5A 3SMEA 4MBBA 4RKKA 1Q6PA 4WU2A 4TVVA 5KA8A 2QBSA 1G4US 1NNYA 3F9AA 5EHRA 2F6FA 2XJAA 1C83A 2CMCA 2I6IA 4UAGA 2Y67A 4JNBA 2OC3A 2QBPA 1WRMA 2I5XA 4JMKA 2UUPA 5KA3A 5KAAA 2VEWA 3RO1A 4KYRA 3ZM0A 2H4KA 4ZI4A 2M3VA 4GE5A 4I8NA 3O5XA 4HJQA 4OHDA 3A5KA 3RZ2A 1E8CA 3V0FA 3CM3A 1LQFA 1WCHA 2I4HA 3D1OA 3EMUA 2B49A 2CM3A 4HJPA 2F6TA 3NRSA 2IMGA 4PYHA 3I36A 1G7GA 4QDIA 1OEUA 4PVGA 1X24A 3QKQA 5KA2A 1PTTA 4BUBA 3D1QA 2Y66A 2ZN7A 2A8BA 3QCFA 1QXKA 3QCJA 4ICZA 2C7SA 4HV4A 1G1GA 2F6YA 2I6OA 2A3KA 1UAGA 2E0TA 2GCAA 3RGQA 3PYZA 4OHIA 2I6MA 1G4WR 4Y14A 3MVNA 3AWGA 5AWXA 2H02A 4C13A 2F00A 1YTSA 2B07A 4GFVA 3SR9A 1JF7A 1ONZA 4GFUA 3PS5A 3S3KA 1OHEA 2GP0A 3QCKA 4BPCA 4NNDA 3OMHA 2VEYA 3N2AA 1OEMX 4IKCA 1D5RA 1G7FA 3NMEA 4NWFA 5GTJA 1PXHA 2NLKA 1Q6MA 5A5FA 2QCJA 1YTWA 3EAXA 3U96A 1OEOX 4NYHA 4QAPA 4D3PA 2FJNA 1SUGA 2I4GA 2GC5A 2F46A 3QCZA 2VOSA 5BUGA 1G1FA 3BLUA 4JMJA 3BRHA 2F71A 4DGXA 3EB1A 1C85A 2RF6A 2HNPA 3F99A 2I75A 2QDPA 4GE2A 2VTEA 2H03A 4GWFA 2R0BA 2B4OA 2VORA 1PTUA 4GE6A 2CNFA 5KA7A 3V0DA 4RDDA 1U25A 1C88A 3V0IA 2Y68A 4OHEA 3QCLA 3AWFA 2F6WA 5K25A 1YWFA 1I57A 2CM2A 2UAGA 2QBRA 2J16B 2AM2A 1Q6TA 2JFHA 2FJMA 5BZZA 4D3QA 4CVLA 3ZV2A 2UUOA 1Q1MA 4J51A 1P31A 2HVLA 3A5JA 3S3HA 3LK7A 3S4OA 5KADA 2WJPA 2NTAA 2PQ5A 2MBCA 3ZM2A 3QKPA 1FGSA 3MOWA 1Q6NA 1Q6JA 5LXQB 1OHDA 3QCCA 2Y1OA 1WAXA 2JJDA 4WTYA 4QBEA 3QCDA 2HCMA 1YGRA 2I1YA 3QCEA 2OZ5A 2CJZA 3H2XA 3V0HA 2I3UA 1LYVA 1XM2A 4DGPA 3GXGA 3QCGA 1RPMA 2QBQA 3QCMA 2ZMMA 1Q6SA 2I6PA 3O3LA 1OESA 2P6XA 2NV5A 5EHPA 1YTNA 3QCIA 5IBSA 1C87A 1NWEA 2WGPA 2BZLA 1KAKA 2NZ6A 1YPTA 2Y96A 3BM8A 4KI9A 5A5EA 1BZJA 3GXHA 4YAAA 1OEVA 4QF5A 1P3DA 1RXDA 2X5OA 1XXVA 4BUCA 2XPCA 1NO6A 1EEOA 5KA0A 2HY3A 3QCNA 2H4VA 4ERCA 3V0JA 1M3GA 1KAVA 2F6ZA 4Z6BA 5KA4A 2NT2A 2Y2FA 2GCBA 5I6VA 2C46A 2CNHA 3N0AA 4QUMA 3UAGA 2F6VA 1EENA 3D9CA 2BIJA 1C84A 1V3AA 2CFVA 2F70A 1L8KA 3O4TA 1YZ4A 2SHPA 2G59A 1PTVA 1PTYA 2QDCA 3ZM6A 4GRYA 3ZL8A 2AHSA 3O4UA 1NWLA 1PA1A 3AWEA 1XBOA 4YR8B 1JLNA 4S0GA 1GFYA 3QCBA 2PA5A 1P15A 1YFOA 1AAXA 1QZ0A 1W7KA 5K22A 4RI4A 2JFGA 3B7OA 3V0EA 1FQ1A 1R6HA 1ECVA 4C12A 1FPRA 2B4SA 2B4UA 4R0TA 1GQQA 2GJTA 1PH0A 1XRIA 2VEVA 2H4GA 4Y2EA 1I9SA 1XXPA 5IBMA 1YGUA 1BZHA 1J4XA 1FPZA 2H04A 3LJ8A 1YN9A 2FH7A 2I3RA 5K23A 1O5ZA 1J6UA 3O4SA 2I42A 2HXPA 4ZN5A 3S3EA 2VTDA 3RGOA 2BGEA 2CMAA 2CM8A 2I4EA 4QUNA 3MOZA 1ZCLA 4ZRTA 2AM1A 2P4DA 1GWZA 3F9BA 4OHLA 5BZXA 1PYNA 2QCTA 4RH9A 2CM7A 3D44A 1MKPA 5J8RA 2AZRA 2I6JA 2PT0A 2WTZA 4AZ1A 4NX8A 4GRZA 1A5YA 2G6ZA 1ZC0A 4RI5A 3D42A 3EU0A 2VEUA 2OOQA 5HDEA 5K9WA 2YDUA 4H34A 4CVMA 4GS0A 2JFFA 3HN7A 3ZM3A 1ZZWA 5MMZB 5KA1A 1GG4A 4H1OA 4WOHA 4BJOA 3F41A 2HC1A 2CNEA 2DXPA 4HRFA 4D3RA 1JBVA 3S3FA 2PBNA 1NL9A 3I7ZA 5K9VA 1JBWA 2Q05A 3M4UA 2QDMA 2CNIA 5K24A 2CMBA 2PSZA 4R0SA 1T48A 3ZMPA 4B04A 2BGDA 3BLTA 2ESBA 1T49A 3V0GA 2HNQA 4QBWA 1T4JA 3CWEA 2GC6A 1NZ7A 2B4PA 2HB1A 1L8GA 1VHRA 4WU3A 3ZMQA 3MMJA 4OHHA 4CVKA 1E0DA 3ZM1A 1EEHA 4JBCA 2J16A 2OUDA 3ZM5A 2HC2A 1I9TA 1OHCA 1PA9A 2Q47A 1LARA 4R30A 4NWGA 1W78A 1U24A 1U26A 3S4EA 1GQYA 3I80A 2VEXA 3EZZA 4RHGA 1G1HA 3F81A 5KABA
chains in the Genus database with same CATH topology
1BZCA 1ZCKA 2CNGA 4RH5A 5KACA 2PI7A 2B3OA 4QAHA 1C86A 1ONYA 2GWOA 5BX1A 3D1HA 3OLRA 4KYQA 1OETA 2QEPA 2J17A 5M43A 2NT7A 5KA9A 3QCHA 2BV5A 3SMEA 4MBBA 4RKKA 1Q6PA 4WU2A 4TVVA 5KA8A 2QBSA 1G4US 1NNYA 3F9AA 5EHRA 2F6FA 1C83A 2CMCA 2I6IA 4JNBA 2OC3A 2QBPA 1WRMA 2I5XA 4JMKA 5KA3A 5KAAA 2VEWA 3RO1A 4KYRA 3ZM0A 2H4KA 4ZI4A 2M3VA 4GE5A 4I8NA 3O5XA 4HJQA 4OHDA 3A5KA 3RZ2A 3V0FA 3CM3A 1LQFA 1WCHA 2I4HA 3D1OA 3EMUA 2B49A 2CM3A 4HJPA 2F6TA 2IMGA 4PYHA 3I36A 1G7GA 1OEUA 4PVGA 1X24A 3QKQA 5KA2A 1PTTA 3D1QA 2ZN7A 2A8BA 3QCFA 1QXKA 3QCJA 4ICZA 2C7SA 1G1GA 2F6YA 2I6OA 2A3KA 2E0TA 3RGQA 4OHIA 2I6MA 1G4WR 4Y14A 3AWGA 5AWXA 2H02A 1YTSA 2B07A 4GFVA 3SR9A 1JF7A 1ONZA 4GFUA 3PS5A 3S3KA 1OHEA 2GP0A 3QCKA 4BPCA 4NNDA 3OMHA 2VEYA 1OEMX 4IKCA 1D5RA 1G7FA 3NMEA 4NWFA 5GTJA 1PXHA 2NLKA 1Q6MA 2QCJA 1YTWA 3EAXA 3U96A 1OEOX 4NYHA 4QAPA 4D3PA 2FJNA 1SUGA 2I4GA 2F46A 5BUGA 1G1FA 3BLUA 4JMJA 3BRHA 2F71A 4DGXA 3EB1A 1C85A 2RF6A 2HNPA 3F99A 2I75A 2QDPA 4GE2A 2H03A 4GWFA 2R0BA 2B4OA 1PTUA 4GE6A 2CNFA 5KA7A 3V0DA 4RDDA 1U25A 1C88A 3V0IA 4OHEA 3QCLA 3AWFA 2F6WA 5K25A 1YWFA 1I57A 2CM2A 2J16B 2QBRA 5BZZA 1Q6TA 2FJMA 4D3QA 3ZV2A 1Q1MA 4J51A 2HVLA 3A5JA 3S3HA 3S4OA 5KADA 2NTAA 2PQ5A 2MBCA 3ZM2A 3QKPA 3MOWA 1Q6NA 1Q6JA 5LXQB 1OHDA 3QCCA 1WAXA 2JJDA 4WTYA 4QBEA 3QCDA 2HCMA 1YGRA 2I1YA 3QCEA 2OZ5A 2CJZA 3H2XA 3V0HA 2I3UA 1LYVA 1XM2A 4DGPA 3QCGA 3GXGA 1RPMA 2QBQA 3QCMA 2ZMMA 1Q6SA 2I6PA 3O3LA 1OESA 2P6XA 2NV5A 5EHPA 1YTNA 3QCIA 5IBSA 1C87A 1NWEA 2WGPA 2BZLA 1KAKA 2NZ6A 1YPTA 2Y96A 3BM8A 4KI9A 1BZJA 3GXHA 4YAAA 1OEVA 1RXDA 1XXVA 1NO6A 1EEOA 5KA0A 2HY3A 3QCNA 2H4VA 4ERCA 3V0JA 1M3GA 1KAVA 2F6ZA 4Z6BA 5KA4A 2NT2A 2Y2FA 5I6VA 2C46A 2CNHA 3N0AA 4QUMA 2F6VA 1EENA 3D9CA 2BIJA 1C84A 1V3AA 2CFVA 2F70A 1L8KA 3O4TA 1YZ4A 2SHPA 2G59A 1PTVA 1PTYA 2QDCA 4GRYA 2AHSA 3O4UA 1NWLA 1PA1A 3AWEA 1XBOA 4YR8B 1JLNA 4S0GA 1GFYA 3QCBA 2PA5A 1P15A 1YFOA 1AAXA 1QZ0A 5K22A 4RI4A 3B7OA 3V0EA 1FQ1A 1R6HA 1ECVA 1FPRA 2B4SA 2B4UA 4R0TA 2GJTA 1PH0A 1XRIA 2VEVA 2H4GA 4Y2EA 1I9SA 1XXPA 5IBMA 1YGUA 1BZHA 1J4XA 1FPZA 2H04A 3LJ8A 1YN9A 2FH7A 2I3RA 5K23A 3O4SA 2I42A 2HXPA 4ZN5A 3S3EA 3RGOA 2BGEA 2CMAA 2CM8A 2I4EA 4QUNA 3MOZA 1ZCLA 4ZRTA 2P4DA 1GWZA 3F9BA 4OHLA 5BZXA 1PYNA 2QCTA 4RH9A 2CM7A 3D44A 1MKPA 5J8RA 2AZRA 2I6JA 2PT0A 4AZ1A 4NX8A 4GRZA 1A5YA 2G6ZA 1ZC0A 4RI5A 3D42A 3EU0A 2VEUA 2OOQA 5HDEA 5K9WA 2YDUA 4H34A 4GS0A 3ZM3A 1ZZWA 5MMZB 5KA1A 4H1OA 4WOHA 4BJOA 3F41A 2HC1A 2CNEA 2DXPA 4HRFA 4D3RA 3S3FA 2PBNA 1NL9A 3I7ZA 5K9VA 2Q05A 3M4UA 2QDMA 2CNIA 5K24A 2CMBA 2PSZA 4R0SA 1T48A 3ZMPA 4B04A 2BGDA 3BLTA 2ESBA 1T49A 3V0GA 2HNQA 4QBWA 1T4JA 3CWEA 1NZ7A 2B4PA 2HB1A 1L8GA 1VHRA 4WU3A 3ZMQA 3MMJA 4OHHA 3ZM1A 4JBCA 2J16A 2OUDA 2HC2A 1I9TA 1OHCA 1PA9A 2Q47A 1LARA 4R30A 4NWGA 1U24A 1U26A 3S4EA 3I80A 2VEXA 3EZZA 4RHGA 1G1HA 3F81A 5KABA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BZC A;  1ZCK A;  2CNG A;  4RH5 A;  5KAC A;  2PI7 A;  2B3O A;  4QAH A;  1C86 A;  1ONY A;  2GWO A;  5BX1 A;  3D1H A;  3OLR A;  4KYQ A;  1OET A;  2QEP A;  2J17 A;  5M43 A;  2NT7 A;  5KA9 A;  3QCH A;  2BV5 A;  3SME A;  4MBB A;  4RKK A;  1Q6P A;  4WU2 A;  4TVV A;  5KA8 A;  2QBS A;  1G4U S;  1NNY A;  3F9A A;  5EHR A;  2F6F A;  1C83 A;  2CMC A;  2I6I A;  4JNB A;  2OC3 A;  2QBP A;  1WRM A;  2I5X A;  4JMK A;  5KA3 A;  5KAA A;  2VEW A;  3RO1 A;  4KYR A;  3ZM0 A;  2H4K A;  4ZI4 A;  2M3V A;  4GE5 A;  4I8N A;  3O5X A;  4HJQ A;  4OHD A;  3A5K A;  3RZ2 A;  3V0F A;  3CM3 A;  1LQF A;  1WCH A;  2I4H A;  3D1O A;  3EMU A;  2B49 A;  2CM3 A;  4HJP A;  2F6T A;  2IMG A;  4PYH A;  3I36 A;  1G7G A;  1OEU A;  4PVG A;  1X24 A;  3QKQ A;  5KA2 A;  1PTT A;  3D1Q A;  2ZN7 A;  2A8B A;  3QCF A;  1QXK A;  3QCJ A;  4ICZ A;  2C7S A;  1G1G A;  2F6Y A;  2I6O A;  2A3K A;  2E0T A;  3RGQ A;  4OHI A;  2I6M A;  1G4W R;  4Y14 A;  3AWG A;  5AWX A;  2H02 A;  1YTS A;  2B07 A;  4GFV A;  3SR9 A;  1JF7 A;  1ONZ A;  4GFU A;  3PS5 A;  3S3K A;  1OHE A;  2GP0 A;  3QCK A;  4BPC A;  4NND A;  3OMH A;  2VEY A;  1OEM X;  4IKC A;  1D5R A;  1G7F A;  3NME A;  4NWF A;  5GTJ A;  1PXH A;  2NLK A;  1Q6M A;  2QCJ A;  1YTW A;  3EAX A;  3U96 A;  1OEO X;  4NYH A;  4QAP A;  4D3P A;  2FJN A;  1SUG A;  2I4G A;  2F46 A;  5BUG A;  1G1F A;  3BLU A;  4JMJ A;  3BRH A;  2F71 A;  4DGX A;  3EB1 A;  1C85 A;  2RF6 A;  2HNP A;  3F99 A;  2I75 A;  2QDP A;  4GE2 A;  2H03 A;  4GWF A;  2R0B A;  2B4O A;  1PTU A;  4GE6 A;  2CNF A;  5KA7 A;  3V0D A;  4RDD A;  1U25 A;  1C88 A;  3V0I A;  4OHE A;  3QCL A;  3AWF A;  2F6W A;  5K25 A;  1YWF A;  1I57 A;  2CM2 A;  2J16 B;  2QBR A;  5BZZ A;  1Q6T A;  2FJM A;  4D3Q A;  3ZV2 A;  1Q1M A;  4J51 A;  2HVL A;  3A5J A;  3S3H A;  3S4O A;  5KAD A;  2NTA A;  2PQ5 A;  2MBC A;  3ZM2 A;  3QKP A;  3MOW A;  1Q6N A;  1Q6J A;  5LXQ B;  1OHD A;  3QCC A;  1WAX A;  2JJD A;  4WTY A;  4QBE A;  3QCD A;  2HCM A;  1YGR A;  2I1Y A;  3QCE A;  2OZ5 A;  2CJZ A;  3H2X A;  3V0H A;  2I3U A;  1LYV A;  1XM2 A;  4DGP A;  3QCG A;  3GXG A;  1RPM A;  2QBQ A;  3QCM A;  2ZMM A;  1Q6S A;  2I6P A;  3O3L A;  1OES A;  2P6X A;  2NV5 A;  5EHP A;  1YTN A;  3QCI A;  5IBS A;  1C87 A;  1NWE A;  2WGP A;  2BZL A;  1KAK A;  2NZ6 A;  1YPT A;  2Y96 A;  3BM8 A;  4KI9 A;  1BZJ A;  3GXH A;  4YAA A;  1OEV A;  1RXD A;  1XXV A;  1NO6 A;  1EEO A;  5KA0 A;  2HY3 A;  3QCN A;  2H4V A;  4ERC A;  3V0J A;  1M3G A;  1KAV A;  2F6Z A;  4Z6B A;  5KA4 A;  2NT2 A;  2Y2F A;  5I6V A;  2C46 A;  2CNH A;  3N0A A;  4QUM A;  2F6V A;  1EEN A;  3D9C A;  2BIJ A;  1C84 A;  1V3A A;  2CFV A;  2F70 A;  1L8K A;  3O4T A;  1YZ4 A;  2SHP A;  2G59 A;  1PTV A;  1PTY A;  2QDC A;  4GRY A;  2AHS A;  3O4U A;  1NWL A;  1PA1 A;  3AWE A;  1XBO A;  4YR8 B;  1JLN A;  4S0G A;  1GFY A;  3QCB A;  2PA5 A;  1P15 A;  1YFO A;  1AAX A;  1QZ0 A;  5K22 A;  4RI4 A;  3B7O A;  3V0E A;  1FQ1 A;  1R6H A;  1ECV A;  1FPR A;  2B4S A;  2B4U A;  4R0T A;  2GJT A;  1PH0 A;  1XRI A;  2VEV A;  2H4G A;  4Y2E A;  1I9S A;  1XXP A;  5IBM A;  1YGU A;  1BZH A;  1J4X A;  1FPZ A;  2H04 A;  3LJ8 A;  1YN9 A;  2FH7 A;  2I3R A;  5K23 A;  3O4S A;  2I42 A;  2HXP A;  4ZN5 A;  3S3E A;  3RGO A;  2BGE A;  2CMA A;  2CM8 A;  2I4E A;  4QUN A;  3MOZ A;  1ZCL A;  4ZRT A;  2P4D A;  1GWZ A;  3F9B A;  4OHL A;  5BZX A;  1PYN A;  2QCT A;  4RH9 A;  2CM7 A;  3D44 A;  1MKP A;  5J8R A;  2AZR A;  2I6J A;  2PT0 A;  4AZ1 A;  4NX8 A;  4GRZ A;  1A5Y A;  2G6Z A;  1ZC0 A;  4RI5 A;  3D42 A;  3EU0 A;  2VEU A;  2OOQ A;  5HDE A;  5K9W A;  2YDU A;  4H34 A;  4GS0 A;  3ZM3 A;  1ZZW A;  5MMZ B;  5KA1 A;  4H1O A;  4WOH A;  4BJO A;  3F41 A;  2HC1 A;  2CNE A;  2DXP A;  4HRF A;  4D3R A;  3S3F A;  2PBN A;  1NL9 A;  3I7Z A;  5K9V A;  2Q05 A;  3M4U A;  2QDM A;  2CNI A;  5K24 A;  2CMB A;  2PSZ A;  4R0S A;  1T48 A;  3ZMP A;  4B04 A;  2BGD A;  3BLT A;  2ESB A;  1T49 A;  3V0G A;  2HNQ A;  4QBW A;  1T4J A;  3CWE A;  1NZ7 A;  2B4P A;  2HB1 A;  1L8G A;  1VHR A;  4WU3 A;  3ZMQ A;  3MMJ A;  4OHH A;  3ZM1 A;  4JBC A;  2J16 A;  2OUD A;  2HC2 A;  1I9T A;  1OHC A;  1PA9 A;  2Q47 A;  1LAR A;  4R30 A;  4NWG A;  1U24 A;  1U26 A;  3S4E A;  3I80 A;  2VEX A;  3EZZ A;  4RHG A;  1G1H A;  3F81 A;  5KAB A; 
#chains in the Genus database with same CATH topology
 1BZC A;  1ZCK A;  2CNG A;  4RH5 A;  5KAC A;  2PI7 A;  2B3O A;  4QAH A;  1C86 A;  1ONY A;  2GWO A;  5BX1 A;  3D1H A;  3OLR A;  4KYQ A;  1OET A;  2QEP A;  4ZIY A;  2J17 A;  5M43 A;  2NT7 A;  5KA9 A;  3QCH A;  2BV5 A;  3SME A;  4MBB A;  4RKK A;  1Q6P A;  4WU2 A;  4TVV A;  5KA8 A;  2QBS A;  1G4U S;  1NNY A;  3F9A A;  5EHR A;  2F6F A;  2XJA A;  1C83 A;  2CMC A;  2I6I A;  4UAG A;  2Y67 A;  4JNB A;  2OC3 A;  2QBP A;  1WRM A;  2I5X A;  4JMK A;  2UUP A;  5KA3 A;  5KAA A;  2VEW A;  3RO1 A;  4KYR A;  3ZM0 A;  2H4K A;  4ZI4 A;  2M3V A;  4GE5 A;  4I8N A;  3O5X A;  4HJQ A;  4OHD A;  3A5K A;  3RZ2 A;  1E8C A;  3V0F A;  3CM3 A;  1LQF A;  1WCH A;  2I4H A;  3D1O A;  3EMU A;  2B49 A;  2CM3 A;  4HJP A;  2F6T A;  3NRS A;  2IMG A;  4PYH A;  3I36 A;  1G7G A;  4QDI A;  1OEU A;  4PVG A;  1X24 A;  3QKQ A;  5KA2 A;  1PTT A;  4BUB A;  3D1Q A;  2Y66 A;  2ZN7 A;  2A8B A;  3QCF A;  1QXK A;  3QCJ A;  4ICZ A;  2C7S A;  4HV4 A;  1G1G A;  2F6Y A;  2I6O A;  2A3K A;  1UAG A;  2E0T A;  2GCA A;  3RGQ A;  3PYZ A;  4OHI A;  2I6M A;  1G4W R;  4Y14 A;  3MVN A;  3AWG A;  5AWX A;  2H02 A;  4C13 A;  2F00 A;  1YTS A;  2B07 A;  4GFV A;  3SR9 A;  1JF7 A;  1ONZ A;  4GFU A;  3PS5 A;  3S3K A;  1OHE A;  2GP0 A;  3QCK A;  4BPC A;  4NND A;  3OMH A;  2VEY A;  3N2A A;  1OEM X;  4IKC A;  1D5R A;  1G7F A;  3NME A;  4NWF A;  5GTJ A;  1PXH A;  2NLK A;  1Q6M A;  5A5F A;  2QCJ A;  1YTW A;  3EAX A;  3U96 A;  1OEO X;  4NYH A;  4QAP A;  4D3P A;  2FJN A;  1SUG A;  2I4G A;  2GC5 A;  2F46 A;  3QCZ A;  2VOS A;  5BUG A;  1G1F A;  3BLU A;  4JMJ A;  3BRH A;  2F71 A;  4DGX A;  3EB1 A;  1C85 A;  2RF6 A;  2HNP A;  3F99 A;  2I75 A;  2QDP A;  4GE2 A;  2VTE A;  2H03 A;  4GWF A;  2R0B A;  2B4O A;  2VOR A;  1PTU A;  4GE6 A;  2CNF A;  5KA7 A;  3V0D A;  4RDD A;  1U25 A;  1C88 A;  3V0I A;  2Y68 A;  4OHE A;  3QCL A;  3AWF A;  2F6W A;  5K25 A;  1YWF A;  1I57 A;  2CM2 A;  2UAG A;  2QBR A;  2J16 B;  2AM2 A;  1Q6T A;  2JFH A;  2FJM A;  5BZZ A;  4D3Q A;  4CVL A;  3ZV2 A;  2UUO A;  1Q1M A;  4J51 A;  1P31 A;  2HVL A;  3A5J A;  3S3H A;  3LK7 A;  3S4O A;  5KAD A;  2WJP A;  2NTA A;  2PQ5 A;  2MBC A;  3ZM2 A;  3QKP A;  1FGS A;  3MOW A;  1Q6N A;  1Q6J A;  5LXQ B;  1OHD A;  3QCC A;  2Y1O A;  1WAX A;  2JJD A;  4WTY A;  4QBE A;  3QCD A;  2HCM A;  1YGR A;  2I1Y A;  3QCE A;  2OZ5 A;  2CJZ A;  3H2X A;  3V0H A;  2I3U A;  1LYV A;  1XM2 A;  4DGP A;  3GXG A;  3QCG A;  1RPM A;  2QBQ A;  3QCM A;  2ZMM A;  1Q6S A;  2I6P A;  3O3L A;  1OES A;  2P6X A;  2NV5 A;  5EHP A;  1YTN A;  3QCI A;  5IBS A;  1C87 A;  1NWE A;  2WGP A;  2BZL A;  1KAK A;  2NZ6 A;  1YPT A;  2Y96 A;  3BM8 A;  4KI9 A;  5A5E A;  1BZJ A;  3GXH A;  4YAA A;  1OEV A;  4QF5 A;  1P3D A;  1RXD A;  2X5O A;  1XXV A;  4BUC A;  2XPC A;  1NO6 A;  1EEO A;  5KA0 A;  2HY3 A;  3QCN A;  2H4V A;  4ERC A;  3V0J A;  1M3G A;  1KAV A;  2F6Z A;  4Z6B A;  5KA4 A;  2NT2 A;  2Y2F A;  2GCB A;  5I6V A;  2C46 A;  2CNH A;  3N0A A;  4QUM A;  3UAG A;  2F6V A;  1EEN A;  3D9C A;  2BIJ A;  1C84 A;  1V3A A;  2CFV A;  2F70 A;  1L8K A;  3O4T A;  1YZ4 A;  2SHP A;  2G59 A;  1PTV A;  1PTY A;  2QDC A;  3ZM6 A;  4GRY A;  3ZL8 A;  2AHS A;  3O4U A;  1NWL A;  1PA1 A;  3AWE A;  1XBO A;  4YR8 B;  1JLN A;  4S0G A;  1GFY A;  3QCB A;  2PA5 A;  1P15 A;  1YFO A;  1AAX A;  1QZ0 A;  1W7K A;  5K22 A;  4RI4 A;  2JFG A;  3B7O A;  3V0E A;  1FQ1 A;  1R6H A;  1ECV A;  4C12 A;  1FPR A;  2B4S A;  2B4U A;  4R0T A;  1GQQ A;  2GJT A;  1PH0 A;  1XRI A;  2VEV A;  2H4G A;  4Y2E A;  1I9S A;  1XXP A;  5IBM A;  1YGU A;  1BZH A;  1J4X A;  1FPZ A;  2H04 A;  3LJ8 A;  1YN9 A;  2FH7 A;  2I3R A;  5K23 A;  1O5Z A;  1J6U A;  3O4S A;  2I42 A;  2HXP A;  4ZN5 A;  3S3E A;  2VTD A;  3RGO A;  2BGE A;  2CMA A;  2CM8 A;  2I4E A;  4QUN A;  3MOZ A;  1ZCL A;  4ZRT A;  2AM1 A;  2P4D A;  1GWZ A;  3F9B A;  4OHL A;  5BZX A;  1PYN A;  2QCT A;  4RH9 A;  2CM7 A;  3D44 A;  1MKP A;  5J8R A;  2AZR A;  2I6J A;  2PT0 A;  2WTZ A;  4AZ1 A;  4NX8 A;  4GRZ A;  1A5Y A;  2G6Z A;  1ZC0 A;  4RI5 A;  3D42 A;  3EU0 A;  2VEU A;  2OOQ A;  5HDE A;  5K9W A;  2YDU A;  4H34 A;  4CVM A;  4GS0 A;  2JFF A;  3HN7 A;  3ZM3 A;  1ZZW A;  5MMZ B;  5KA1 A;  1GG4 A;  4H1O A;  4WOH A;  4BJO A;  3F41 A;  2HC1 A;  2CNE A;  2DXP A;  4HRF A;  4D3R A;  1JBV A;  3S3F A;  2PBN A;  1NL9 A;  3I7Z A;  5K9V A;  1JBW A;  2Q05 A;  3M4U A;  2QDM A;  2CNI A;  5K24 A;  2CMB A;  2PSZ A;  4R0S A;  1T48 A;  3ZMP A;  4B04 A;  2BGD A;  3BLT A;  2ESB A;  1T49 A;  3V0G A;  2HNQ A;  4QBW A;  1T4J A;  3CWE A;  2GC6 A;  1NZ7 A;  2B4P A;  2HB1 A;  1L8G A;  1VHR A;  4WU3 A;  3ZMQ A;  3MMJ A;  4OHH A;  4CVK A;  1E0D A;  3ZM1 A;  1EEH A;  4JBC A;  2J16 A;  2OUD A;  3ZM5 A;  2HC2 A;  1I9T A;  1OHC A;  1PA9 A;  2Q47 A;  1LAR A;  4R30 A;  4NWG A;  1W78 A;  1U24 A;  1U26 A;  3S4E A;  1GQY A;  3I80 A;  2VEX A;  3EZZ A;  4RHG A;  1G1H A;  3F81 A;  5KAB A; 
#chains in the Genus database with same CATH homology
 1BZC A;  1ZCK A;  2CNG A;  4RH5 A;  5KAC A;  2PI7 A;  2B3O A;  4QAH A;  1C86 A;  1ONY A;  2GWO A;  5BX1 A;  3D1H A;  3OLR A;  4KYQ A;  1OET A;  2QEP A;  2J17 A;  5M43 A;  2NT7 A;  5KA9 A;  3QCH A;  2BV5 A;  3SME A;  4MBB A;  4RKK A;  1Q6P A;  4WU2 A;  4TVV A;  5KA8 A;  2QBS A;  1G4U S;  1NNY A;  3F9A A;  5EHR A;  2F6F A;  1C83 A;  2CMC A;  2I6I A;  4JNB A;  2OC3 A;  2QBP A;  1WRM A;  2I5X A;  4JMK A;  5KA3 A;  5KAA A;  2VEW A;  3RO1 A;  4KYR A;  3ZM0 A;  2H4K A;  4ZI4 A;  2M3V A;  4GE5 A;  4I8N A;  3O5X A;  4HJQ A;  4OHD A;  3A5K A;  3RZ2 A;  3V0F A;  3CM3 A;  1LQF A;  1WCH A;  2I4H A;  3D1O A;  3EMU A;  2B49 A;  2CM3 A;  4HJP A;  2F6T A;  2IMG A;  4PYH A;  3I36 A;  1G7G A;  1OEU A;  4PVG A;  1X24 A;  3QKQ A;  5KA2 A;  1PTT A;  3D1Q A;  2ZN7 A;  2A8B A;  3QCF A;  1QXK A;  3QCJ A;  4ICZ A;  2C7S A;  1G1G A;  2F6Y A;  2I6O A;  2A3K A;  2E0T A;  3RGQ A;  4OHI A;  2I6M A;  1G4W R;  4Y14 A;  3AWG A;  5AWX A;  2H02 A;  1YTS A;  2B07 A;  4GFV A;  3SR9 A;  1JF7 A;  1ONZ A;  4GFU A;  3PS5 A;  3S3K A;  1OHE A;  2GP0 A;  3QCK A;  4BPC A;  4NND A;  3OMH A;  2VEY A;  1OEM X;  4IKC A;  1D5R A;  1G7F A;  3NME A;  4NWF A;  5GTJ A;  1PXH A;  2NLK A;  1Q6M A;  2QCJ A;  1YTW A;  3EAX A;  3U96 A;  1OEO X;  4NYH A;  4QAP A;  4D3P A;  2FJN A;  1SUG A;  2I4G A;  2F46 A;  5BUG A;  1G1F A;  3BLU A;  4JMJ A;  3BRH A;  2F71 A;  4DGX A;  3EB1 A;  1C85 A;  2RF6 A;  2HNP A;  3F99 A;  2I75 A;  2QDP A;  4GE2 A;  2H03 A;  4GWF A;  2R0B A;  2B4O A;  1PTU A;  4GE6 A;  2CNF A;  5KA7 A;  3V0D A;  4RDD A;  1U25 A;  1C88 A;  3V0I A;  4OHE A;  3QCL A;  3AWF A;  2F6W A;  5K25 A;  1YWF A;  1I57 A;  2CM2 A;  2J16 B;  2QBR A;  5BZZ A;  1Q6T A;  2FJM A;  4D3Q A;  3ZV2 A;  1Q1M A;  4J51 A;  2HVL A;  3A5J A;  3S3H A;  3S4O A;  5KAD A;  2NTA A;  2PQ5 A;  2MBC A;  3ZM2 A;  3QKP A;  3MOW A;  1Q6N A;  1Q6J A;  5LXQ B;  1OHD A;  3QCC A;  1WAX A;  2JJD A;  4WTY A;  4QBE A;  3QCD A;  2HCM A;  1YGR A;  2I1Y A;  3QCE A;  2OZ5 A;  2CJZ A;  3H2X A;  3V0H A;  2I3U A;  1LYV A;  1XM2 A;  4DGP A;  3QCG A;  3GXG A;  1RPM A;  2QBQ A;  3QCM A;  2ZMM A;  1Q6S A;  2I6P A;  3O3L A;  1OES A;  2P6X A;  2NV5 A;  5EHP A;  1YTN A;  3QCI A;  5IBS A;  1C87 A;  1NWE A;  2WGP A;  2BZL A;  1KAK A;  2NZ6 A;  1YPT A;  2Y96 A;  3BM8 A;  4KI9 A;  1BZJ A;  3GXH A;  4YAA A;  1OEV A;  1RXD A;  1XXV A;  1NO6 A;  1EEO A;  5KA0 A;  2HY3 A;  3QCN A;  2H4V A;  4ERC A;  3V0J A;  1M3G A;  1KAV A;  2F6Z A;  4Z6B A;  5KA4 A;  2NT2 A;  2Y2F A;  5I6V A;  2C46 A;  2CNH A;  3N0A A;  4QUM A;  2F6V A;  1EEN A;  3D9C A;  2BIJ A;  1C84 A;  1V3A A;  2CFV A;  2F70 A;  1L8K A;  3O4T A;  1YZ4 A;  2SHP A;  2G59 A;  1PTV A;  1PTY A;  2QDC A;  4GRY A;  2AHS A;  3O4U A;  1NWL A;  1PA1 A;  3AWE A;  1XBO A;  4YR8 B;  1JLN A;  4S0G A;  1GFY A;  3QCB A;  2PA5 A;  1P15 A;  1YFO A;  1AAX A;  1QZ0 A;  5K22 A;  4RI4 A;  3B7O A;  3V0E A;  1FQ1 A;  1R6H A;  1ECV A;  1FPR A;  2B4S A;  2B4U A;  4R0T A;  2GJT A;  1PH0 A;  1XRI A;  2VEV A;  2H4G A;  4Y2E A;  1I9S A;  1XXP A;  5IBM A;  1YGU A;  1BZH A;  1J4X A;  1FPZ A;  2H04 A;  3LJ8 A;  1YN9 A;  2FH7 A;  2I3R A;  5K23 A;  3O4S A;  2I42 A;  2HXP A;  4ZN5 A;  3S3E A;  3RGO A;  2BGE A;  2CMA A;  2CM8 A;  2I4E A;  4QUN A;  3MOZ A;  1ZCL A;  4ZRT A;  2P4D A;  1GWZ A;  3F9B A;  4OHL A;  5BZX A;  1PYN A;  2QCT A;  4RH9 A;  2CM7 A;  3D44 A;  1MKP A;  5J8R A;  2AZR A;  2I6J A;  2PT0 A;  4AZ1 A;  4NX8 A;  4GRZ A;  1A5Y A;  2G6Z A;  1ZC0 A;  4RI5 A;  3D42 A;  3EU0 A;  2VEU A;  2OOQ A;  5HDE A;  5K9W A;  2YDU A;  4H34 A;  4GS0 A;  3ZM3 A;  1ZZW A;  5MMZ B;  5KA1 A;  4H1O A;  4WOH A;  4BJO A;  3F41 A;  2HC1 A;  2CNE A;  2DXP A;  4HRF A;  4D3R A;  3S3F A;  2PBN A;  1NL9 A;  3I7Z A;  5K9V A;  2Q05 A;  3M4U A;  2QDM A;  2CNI A;  5K24 A;  2CMB A;  2PSZ A;  4R0S A;  1T48 A;  3ZMP A;  4B04 A;  2BGD A;  3BLT A;  2ESB A;  1T49 A;  3V0G A;  2HNQ A;  4QBW A;  1T4J A;  3CWE A;  1NZ7 A;  2B4P A;  2HB1 A;  1L8G A;  1VHR A;  4WU3 A;  3ZMQ A;  3MMJ A;  4OHH A;  3ZM1 A;  4JBC A;  2J16 A;  2OUD A;  2HC2 A;  1I9T A;  1OHC A;  1PA9 A;  2Q47 A;  1LAR A;  4R30 A;  4NWG A;  1U24 A;  1U26 A;  3S4E A;  3I80 A;  2VEX A;  3EZZ A;  4RHG A;  1G1H A;  3F81 A;  5KAB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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