1FPRA

Crystal structure of the complex formed between the catalytic domain of shp-1 and an in vitro peptide substrate py469 derived from shps-1.
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
284
structure length
284
Chain Sequence
GFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE 1C
total genus 81
structure length 284
sequence length 284
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1fprA00
2OZ5A 1T48A 2I6PA 1BZCA 3QCMA 5KA4A 4WU2A 1YTSA 4OHIA 1PA1A 3EB1A 4WOHA 3I7ZA 4BJOA 2G59A 4Y2EA 1U26A 3NMEA 4RI4A 1MKPA 1D5RA 2B4SA 2B49A 1LYVA 2QCTA 2I1YA 3F81A 4Z6BA 3OMHA 2F6ZA 1ECVA 2RF6A 2AZRA 4JBCA 3AWEA 2CNHA 1JLNA 3I80A 1YFOA 3QCEA 1ZCLA 1OESA 2A8BA 3O3LA 2HXPA 1OETA 4GFVA 1QXKA 2E0TA 4PYHA 4WTYA 4QAHA 4GE2A 4RH5A 2H4KA 1X24A 3CWEA 1G7FA 3ZM2A 3BM8A 3MMJA 2A3KA 3BLTA 2Q47A 5IBMA 2I5XA 2I4GA 1M3GA 2QEPA 4D3RA 4GS0A 1Q6PA 4RHGA 3ZM3A 4DGXA 2CFVA 2NZ6A 2WGPA 2F6VA 3QKPA 2CJZA 2CM2A 3V0HA 4MBBA 1R6HA 3A5JA 3V0FA 3A5KA 2F6TA 3ZM1A 5KADA 2I6MA 2VEVA 3S4OA 3ZMQA 4D3PA 1YTNA 5KA3A 4NWFA 4OHDA 4I8NA 2HB1A 3V0EA 2PBNA 2P6XA 3EU0A 1YPTA 1NNYA 1OEOX 2QBSA 2I4HA 1G1FA 2GJTA 4B04A 1YGUA 1KAKA 3RO1A 2VEUA 5KA2A 2ESBA 4ZI4A 2IMGA 2FJMA 4JMJA 4HRFA 5KACA 2AHSA 1XXPA 1YN9A 1VHRA 1EENA 4HJPA 4DGPA 4YR8B 3QCBA 2HCMA 3V0IA 1OHDA 2QCJA 4OHLA 2I4EA 2ZMMA 2GP0A 1Q6JA 3QKQA 2QBRA 5BZXA 2H04A 2I3UA 1NO6A 1G1HA 4S0GA 1C83A 3QCKA 1U25A 2OOQA 3GXGA 2GWOA 1P15A 4NYHA 3D42A 2NV5A 3O5XA 2YDUA 2HNQA 1Q6NA 4Y14A 3F9AA 3PS5A 3O4UA 1C86A 2QBQA 2I42A 1ZZWA 1NL9A 1XXVA 4NWGA 4GE6A 1XM2A 2FJNA 3EZZA 2H4GA 3D44A 2QDCA 1YZ4A 1I9TA 3GXHA 4IKCA 5BUGA 1L8KA 1NWLA 5K25A 2NT7A 4RH9A 2BIJA 4KI9A 5K22A 2FH7A 2C46A 2F71A 1YGRA 2BGEA 2DXPA 4R0TA 2Y2FA 1PH0A 1ZCKA 3O4TA 3O4SA 4NNDA 3QCNA 3D9CA 2PQ5A 5KAAA 3EMUA 1Q6MA 3RZ2A 3S3FA 1ONYA 4ZN5A 2PSZA 4R30A 2CMCA 5EHRA 3MOZA 1ZC0A 2CMAA 2CNIA 1QZ0A 2Q05A 3S3HA 4AZ1A 1Q6TA 2R0BA 1G4WR 2CNGA 4JMKA 2VEYA 3QCDA 3QCLA 1SUGA 1GFYA 3BLUA 2J17A 2F46A 1OEMX 4NX8A 4GRYA 4H34A 2CM7A 2PT0A 3D1HA 1PXHA 4ZRTA 5MMZB 2B07A 2PI7A 1G7GA 4TVVA 2I3RA 2CM3A 2HY3A 1T4JA 3AWFA 1NZ7A 2F6FA 3V0DA 3RGQA 4KYQA 3RGOA 3ZMPA 1XRIA 3F41A 1FPRA 3QCGA 2MBCA 4H1OA 4GFUA 5AWXA 4QUMA 5BZZA 3I36A 1G1GA 2VEWA 1C88A 1G4US 3ZV2A 2I75A 1I57A 5K23A 2F6YA 3S3EA 4KYRA 1U24A 4HJQA 1PYNA 5K24A 5K9VA 4GRZA 1WAXA 5BX1A 3AWGA 5GTJA 3OLRA 2J16B 2OC3A 2F70A 4RKKA 1FPZA 2B4OA 5KA1A 4RI5A 1OEUA 5HDEA 2P4DA 3S3KA 1BZJA 2OUDA 1LQFA 1C85A 3LJ8A 1Q1MA 2VEXA 4OHEA 2HC1A 3F9BA 5LXQB 1T49A 1C84A 2H02A 5IBSA 2B4UA 3EAXA 2NT2A 4D3QA 5EHPA 1Q6SA 2JJDA 1XBOA 2M3VA 3QCFA 4QUNA 3QCJA 2CM8A 5K9WA 3F99A 3D1QA 5KABA 2QDMA 1WRMA 1GWZA 3SMEA 1RXDA 5I6VA 4BPCA 1PTUA 3QCCA 2PA5A 1YWFA 4GWFA 3H2XA 4J51A 5KA8A 1PTVA 2CNEA 4QAPA 3QCIA 1A5YA 3ZM0A 2I6OA 2BGDA 2NTAA 5M43A 3D1OA 4JNBA 4PVGA 2BV5A 3B7OA 2HC2A 4OHHA 4YAAA 2C7SA 3SR9A 4QBEA 1NWEA 3M4UA 3BRHA 2H4VA 2QBPA 1AAXA 4RDDA 2HNPA 2ZN7A 3QCHA 4GE5A 2G6ZA 1OHEA 1L8GA 1YTWA 1BZHA 5KA9A 4ICZA 3S4EA 2BZLA 1WCHA 1C87A 1OHCA 1FQ1A 1RPMA 2I6JA 2F6WA 1EEOA 2I6IA 5KA0A 2CNFA 1J4XA 2Y96A 1PTTA 1PTYA 1JF7A 2QDPA 3V0JA 4ERCA 2NLKA 2B4PA 2HVLA 5KA7A 1PA9A 2H03A 3U96A 1V3AA 3N0AA 4R0SA 5J8RA 1OEVA 1I9SA 1LARA 3MOWA 2CMBA 1ONZA 2B3OA 3CM3A 4QBWA 3V0GA 4WU3A 1KAVA 2J16A 2SHPA
chains in the Genus database with same CATH superfamily
2OZ5A 1T48A 2I6PA 1BZCA 4QF5A 3QCMA 4CVKA 5KA4A 4WU2A 1YTSA 4OHIA 1PA1A 3EB1A 1W78A 4WOHA 3I7ZA 4BJOA 2G59A 4Y2EA 1U26A 3NMEA 4RI4A 1MKPA 1D5RA 2B4SA 1GG4A 2B49A 1LYVA 2QCTA 2I1YA 3F81A 4Z6BA 3OMHA 2JFGA 2F6ZA 1ECVA 2RF6A 2AZRA 4JBCA 3AWEA 2CNHA 1JLNA 2JFHA 3I80A 1YFOA 5A5EA 2GCAA 5A5FA 3QCEA 1ZCLA 1OESA 2A8BA 3O3LA 2HXPA 2GCBA 1OETA 4GFVA 1E0DA 1QXKA 2E0TA 4PYHA 4WTYA 4QAHA 4GE2A 4RH5A 2H4KA 1X24A 3CWEA 1G7FA 3ZM2A 3BM8A 3MMJA 2A3KA 3BLTA 2Q47A 5IBMA 2I5XA 2I4GA 1M3GA 2QEPA 4D3RA 4GS0A 1Q6PA 4RHGA 3ZM3A 4DGXA 2CFVA 2NZ6A 2WGPA 2F6VA 2UUPA 3QKPA 2CJZA 2CM2A 3V0HA 1JBVA 1R6HA 4MBBA 3A5JA 2VORA 3V0FA 3A5KA 2F6TA 3ZM1A 5KADA 2I6MA 2VEVA 3S4OA 3ZMQA 4D3PA 1YTNA 5KA3A 1P3DA 4NWFA 4OHDA 4I8NA 2HB1A 3V0EA 2PBNA 2P6XA 3EU0A 1YPTA 2Y66A 1NNYA 1OEOX 2QBSA 2I4HA 1G1FA 2GJTA 2WTZA 4B04A 3PYZA 2F00A 1YGUA 1KAKA 3RO1A 2VEUA 5KA2A 2ESBA 4ZI4A 2IMGA 2FJMA 4JMJA 4HRFA 5KACA 2AHSA 1XXPA 1YN9A 1VHRA 1EENA 4HJPA 4DGPA 4YR8B 3QCBA 2HCMA 3V0IA 1OHDA 2QCJA 4OHLA 2I4EA 2AM2A 2ZMMA 2GP0A 1Q6JA 2VTDA 2XPCA 3QKQA 1E8CA 2QBRA 5BZXA 3MVNA 2H04A 2I3UA 1NO6A 1G1HA 4S0GA 1C83A 3QCKA 1U25A 2OOQA 3GXGA 2GWOA 1P15A 4NYHA 3HN7A 3D42A 2NV5A 3O5XA 2YDUA 2HNQA 1Q6NA 4Y14A 3F9AA 3PS5A 3O4UA 1C86A 2QBQA 2I42A 1ZZWA 1NL9A 4CVLA 1XXVA 4NWGA 4GE6A 1XM2A 2FJNA 4C13A 3EZZA 2H4GA 3QCZA 3D44A 2QDCA 1YZ4A 1I9TA 3GXHA 4IKCA 5BUGA 1L8KA 1NWLA 5K25A 3LK7A 2NT7A 4RH9A 1GQQA 2BIJA 4KI9A 5K22A 2FH7A 2C46A 2F71A 1YGRA 2BGEA 2DXPA 2Y67A 4R0TA 2Y2FA 1PH0A 1FGSA 4UAGA 1ZCKA 3O4TA 3O4SA 4NNDA 3QCNA 3D9CA 2PQ5A 5KAAA 3EMUA 1Q6MA 3RZ2A 3S3FA 1ONYA 2AM1A 2PSZA 4R30A 4ZN5A 2CMCA 5EHRA 3MOZA 1ZC0A 2CMAA 2CNIA 1QZ0A 2Q05A 3S3HA 4AZ1A 3NRSA 1Q6TA 2R0BA 1G4WR 2CNGA 4JMKA 2VEYA 3QCDA 3QCLA 3ZL8A 1SUGA 1GFYA 3BLUA 2J17A 2F46A 1OEMX 4NX8A 4GRYA 4H34A 3UAGA 2CM7A 2PT0A 3D1HA 1PXHA 4ZRTA 5MMZB 2B07A 2PI7A 1G7GA 4TVVA 2I3RA 2CM3A 2HY3A 1T4JA 1W7KA 3AWFA 1NZ7A 2F6FA 3V0DA 3RGQA 4KYQA 3RGOA 2Y68A 2XJAA 3ZMPA 1XRIA 3F41A 1FPRA 3QCGA 2MBCA 4H1OA 4GFUA 5AWXA 4QUMA 5BZZA 3I36A 1G1GA 4HV4A 2VEWA 1C88A 1G4US 3ZV2A 2I75A 1I57A 5K23A 2GC5A 2F6YA 3S3EA 4KYRA 1U24A 4HJQA 1PYNA 5K24A 5K9VA 4GRZA 1WAXA 5BX1A 3AWGA 5GTJA 3OLRA 2J16B 2OC3A 2F70A 4RKKA 1FPZA 2B4OA 5KA1A 4RI5A 1OEUA 5HDEA 2P4DA 3S3KA 1BZJA 4QDIA 2OUDA 1LQFA 1C85A 3LJ8A 1O5ZA 2VOSA 1Q1MA 2VEXA 4OHEA 2HC1A 3F9BA 5LXQB 1T49A 1C84A 2H02A 5IBSA 2B4UA 3EAXA 2NT2A 4D3QA 5EHPA 1Q6SA 2JJDA 1XBOA 2M3VA 3QCFA 4QUNA 3QCJA 2CM8A 5K9WA 3F99A 3D1QA 5KABA 2QDMA 1WRMA 1GWZA 3SMEA 2UAGA 3ZM6A 1RXDA 5I6VA 4BPCA 1PTUA 2UUOA 2PA5A 3QCCA 1YWFA 4GWFA 3H2XA 1UAGA 4J51A 5KA8A 1PTVA 2CNEA 4QAPA 3QCIA 1A5YA 3ZM0A 2I6OA 2BGDA 2NTAA 1P31A 5M43A 3D1OA 4JNBA 4PVGA 2BV5A 2WJPA 3B7OA 2Y1OA 2HC2A 4OHHA 2VTEA 4YAAA 2X5OA 2C7SA 3SR9A 4QBEA 1NWEA 3M4UA 4BUBA 3BRHA 3ZM5A 2H4VA 2QBPA 1AAXA 4RDDA 2HNPA 2ZN7A 3QCHA 4GE5A 3N2AA 2G6ZA 1OHEA 1L8GA 4CVMA 1YTWA 1J6UA 1GQYA 1BZHA 5KA9A 1EEHA 4ICZA 3S4EA 1JBWA 2BZLA 1WCHA 1C87A 1OHCA 1FQ1A 1RPMA 2I6JA 2F6WA 1EEOA 2I6IA 5KA0A 2CNFA 1J4XA 2Y96A 1PTTA 1PTYA 1JF7A 2QDPA 3V0JA 4ERCA 2NLKA 2B4PA 2HVLA 2GC6A 2JFFA 5KA7A 4ZIYA 1PA9A 2H03A 4C12A 3U96A 1V3AA 3N0AA 4R0SA 5J8RA 1OEVA 4BUCA 1I9SA 1LARA 3MOWA 2CMBA 1ONZA 2B3OA 3CM3A 4QBWA 3V0GA 4WU3A 1KAVA 2J16A 2SHPA
chains in the Genus database with same CATH topology
2OZ5A 1T48A 2I6PA 1BZCA 3QCMA 5KA4A 4WU2A 1YTSA 4OHIA 1PA1A 3EB1A 4WOHA 3I7ZA 4BJOA 2G59A 4Y2EA 1U26A 3NMEA 4RI4A 1MKPA 1D5RA 2B4SA 2B49A 1LYVA 2QCTA 2I1YA 3F81A 4Z6BA 3OMHA 2F6ZA 1ECVA 2RF6A 2AZRA 4JBCA 3AWEA 2CNHA 1JLNA 3I80A 1YFOA 3QCEA 1ZCLA 1OESA 2A8BA 3O3LA 2HXPA 1OETA 4GFVA 1QXKA 2E0TA 4PYHA 4WTYA 4QAHA 4GE2A 4RH5A 2H4KA 1X24A 3CWEA 1G7FA 3ZM2A 3BM8A 3MMJA 2A3KA 3BLTA 2Q47A 5IBMA 2I5XA 2I4GA 1M3GA 2QEPA 4D3RA 4GS0A 1Q6PA 4RHGA 3ZM3A 4DGXA 2CFVA 2NZ6A 2WGPA 2F6VA 3QKPA 2CJZA 2CM2A 3V0HA 4MBBA 1R6HA 3A5JA 3V0FA 3A5KA 2F6TA 3ZM1A 5KADA 2I6MA 2VEVA 3S4OA 3ZMQA 4D3PA 1YTNA 5KA3A 4NWFA 4OHDA 4I8NA 2HB1A 3V0EA 2PBNA 2P6XA 3EU0A 1YPTA 1NNYA 1OEOX 2QBSA 2I4HA 1G1FA 2GJTA 4B04A 1YGUA 1KAKA 3RO1A 2VEUA 5KA2A 2ESBA 4ZI4A 2IMGA 2FJMA 4JMJA 4HRFA 5KACA 2AHSA 1XXPA 1YN9A 1VHRA 1EENA 4HJPA 4DGPA 4YR8B 3QCBA 2HCMA 3V0IA 1OHDA 2QCJA 4OHLA 2I4EA 2ZMMA 2GP0A 1Q6JA 3QKQA 2QBRA 5BZXA 2H04A 2I3UA 1NO6A 1G1HA 4S0GA 1C83A 3QCKA 1U25A 2OOQA 3GXGA 2GWOA 1P15A 4NYHA 3D42A 2NV5A 3O5XA 2YDUA 2HNQA 1Q6NA 4Y14A 3F9AA 3PS5A 3O4UA 1C86A 2QBQA 2I42A 1ZZWA 1NL9A 1XXVA 4NWGA 4GE6A 1XM2A 2FJNA 3EZZA 2H4GA 3D44A 2QDCA 1YZ4A 1I9TA 3GXHA 4IKCA 5BUGA 1L8KA 1NWLA 5K25A 2NT7A 4RH9A 2BIJA 4KI9A 5K22A 2FH7A 2C46A 2F71A 1YGRA 2BGEA 2DXPA 4R0TA 2Y2FA 1PH0A 1ZCKA 3O4TA 3O4SA 4NNDA 3QCNA 3D9CA 2PQ5A 5KAAA 3EMUA 1Q6MA 3RZ2A 3S3FA 1ONYA 4ZN5A 2PSZA 4R30A 2CMCA 5EHRA 3MOZA 1ZC0A 2CMAA 2CNIA 1QZ0A 2Q05A 3S3HA 4AZ1A 1Q6TA 2R0BA 1G4WR 2CNGA 4JMKA 2VEYA 3QCDA 3QCLA 1SUGA 1GFYA 3BLUA 2J17A 2F46A 1OEMX 4NX8A 4GRYA 4H34A 2CM7A 2PT0A 3D1HA 1PXHA 4ZRTA 5MMZB 2B07A 2PI7A 1G7GA 4TVVA 2I3RA 2CM3A 2HY3A 1T4JA 3AWFA 1NZ7A 2F6FA 3V0DA 3RGQA 4KYQA 3RGOA 3ZMPA 1XRIA 3F41A 1FPRA 3QCGA 2MBCA 4H1OA 4GFUA 5AWXA 4QUMA 5BZZA 3I36A 1G1GA 2VEWA 1C88A 1G4US 3ZV2A 2I75A 1I57A 5K23A 2F6YA 3S3EA 4KYRA 1U24A 4HJQA 1PYNA 5K24A 5K9VA 4GRZA 1WAXA 5BX1A 3AWGA 5GTJA 3OLRA 2J16B 2OC3A 2F70A 4RKKA 1FPZA 2B4OA 5KA1A 4RI5A 1OEUA 5HDEA 2P4DA 3S3KA 1BZJA 2OUDA 1LQFA 1C85A 3LJ8A 1Q1MA 2VEXA 4OHEA 2HC1A 3F9BA 5LXQB 1T49A 1C84A 2H02A 5IBSA 2B4UA 3EAXA 2NT2A 4D3QA 5EHPA 1Q6SA 2JJDA 1XBOA 2M3VA 3QCFA 4QUNA 3QCJA 2CM8A 5K9WA 3F99A 3D1QA 5KABA 2QDMA 1WRMA 1GWZA 3SMEA 1RXDA 5I6VA 4BPCA 1PTUA 3QCCA 2PA5A 1YWFA 4GWFA 3H2XA 4J51A 5KA8A 1PTVA 2CNEA 4QAPA 3QCIA 1A5YA 3ZM0A 2I6OA 2BGDA 2NTAA 5M43A 3D1OA 4JNBA 4PVGA 2BV5A 3B7OA 2HC2A 4OHHA 4YAAA 2C7SA 3SR9A 4QBEA 1NWEA 3M4UA 3BRHA 2H4VA 2QBPA 1AAXA 4RDDA 2HNPA 2ZN7A 3QCHA 4GE5A 2G6ZA 1OHEA 1L8GA 1YTWA 1BZHA 5KA9A 4ICZA 3S4EA 2BZLA 1WCHA 1C87A 1OHCA 1FQ1A 1RPMA 2I6JA 2F6WA 1EEOA 2I6IA 5KA0A 2CNFA 1J4XA 2Y96A 1PTTA 1PTYA 1JF7A 2QDPA 3V0JA 4ERCA 2NLKA 2B4PA 2HVLA 5KA7A 1PA9A 2H03A 3U96A 1V3AA 3N0AA 4R0SA 5J8RA 1OEVA 1I9SA 1LARA 3MOWA 2CMBA 1ONZA 2B3OA 3CM3A 4QBWA 3V0GA 4WU3A 1KAVA 2J16A 2SHPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OZ5 A;  1T48 A;  2I6P A;  1BZC A;  3QCM A;  5KA4 A;  4WU2 A;  1YTS A;  4OHI A;  1PA1 A;  3EB1 A;  4WOH A;  3I7Z A;  4BJO A;  2G59 A;  4Y2E A;  1U26 A;  3NME A;  4RI4 A;  1MKP A;  1D5R A;  2B4S A;  2B49 A;  1LYV A;  2QCT A;  2I1Y A;  3F81 A;  4Z6B A;  3OMH A;  2F6Z A;  1ECV A;  2RF6 A;  2AZR A;  4JBC A;  3AWE A;  2CNH A;  1JLN A;  3I80 A;  1YFO A;  3QCE A;  1ZCL A;  1OES A;  2A8B A;  3O3L A;  2HXP A;  1OET A;  4GFV A;  1QXK A;  2E0T A;  4PYH A;  4WTY A;  4QAH A;  4GE2 A;  4RH5 A;  2H4K A;  1X24 A;  3CWE A;  1G7F A;  3ZM2 A;  3BM8 A;  3MMJ A;  2A3K A;  3BLT A;  2Q47 A;  5IBM A;  2I5X A;  2I4G A;  1M3G A;  2QEP A;  4D3R A;  4GS0 A;  1Q6P A;  4RHG A;  3ZM3 A;  4DGX A;  2CFV A;  2NZ6 A;  2WGP A;  2F6V A;  3QKP A;  2CJZ A;  2CM2 A;  3V0H A;  4MBB A;  1R6H A;  3A5J A;  3V0F A;  3A5K A;  2F6T A;  3ZM1 A;  5KAD A;  2I6M A;  2VEV A;  3S4O A;  3ZMQ A;  4D3P A;  1YTN A;  5KA3 A;  4NWF A;  4OHD A;  4I8N A;  2HB1 A;  3V0E A;  2PBN A;  2P6X A;  3EU0 A;  1YPT A;  1NNY A;  1OEO X;  2QBS A;  2I4H A;  1G1F A;  2GJT A;  4B04 A;  1YGU A;  1KAK A;  3RO1 A;  2VEU A;  5KA2 A;  2ESB A;  4ZI4 A;  2IMG A;  2FJM A;  4JMJ A;  4HRF A;  5KAC A;  2AHS A;  1XXP A;  1YN9 A;  1VHR A;  1EEN A;  4HJP A;  4DGP A;  4YR8 B;  3QCB A;  2HCM A;  3V0I A;  1OHD A;  2QCJ A;  4OHL A;  2I4E A;  2ZMM A;  2GP0 A;  1Q6J A;  3QKQ A;  2QBR A;  5BZX A;  2H04 A;  2I3U A;  1NO6 A;  1G1H A;  4S0G A;  1C83 A;  3QCK A;  1U25 A;  2OOQ A;  3GXG A;  2GWO A;  1P15 A;  4NYH A;  3D42 A;  2NV5 A;  3O5X A;  2YDU A;  2HNQ A;  1Q6N A;  4Y14 A;  3F9A A;  3PS5 A;  3O4U A;  1C86 A;  2QBQ A;  2I42 A;  1ZZW A;  1NL9 A;  1XXV A;  4NWG A;  4GE6 A;  1XM2 A;  2FJN A;  3EZZ A;  2H4G A;  3D44 A;  2QDC A;  1YZ4 A;  1I9T A;  3GXH A;  4IKC A;  5BUG A;  1L8K A;  1NWL A;  5K25 A;  2NT7 A;  4RH9 A;  2BIJ A;  4KI9 A;  5K22 A;  2FH7 A;  2C46 A;  2F71 A;  1YGR A;  2BGE A;  2DXP A;  4R0T A;  2Y2F A;  1PH0 A;  1ZCK A;  3O4T A;  3O4S A;  4NND A;  3QCN A;  3D9C A;  2PQ5 A;  5KAA A;  3EMU A;  1Q6M A;  3RZ2 A;  3S3F A;  1ONY A;  4ZN5 A;  2PSZ A;  4R30 A;  2CMC A;  5EHR A;  3MOZ A;  1ZC0 A;  2CMA A;  2CNI A;  1QZ0 A;  2Q05 A;  3S3H A;  4AZ1 A;  1Q6T A;  2R0B A;  1G4W R;  2CNG A;  4JMK A;  2VEY A;  3QCD A;  3QCL A;  1SUG A;  1GFY A;  3BLU A;  2J17 A;  2F46 A;  1OEM X;  4NX8 A;  4GRY A;  4H34 A;  2CM7 A;  2PT0 A;  3D1H A;  1PXH A;  4ZRT A;  5MMZ B;  2B07 A;  2PI7 A;  1G7G A;  4TVV A;  2I3R A;  2CM3 A;  2HY3 A;  1T4J A;  3AWF A;  1NZ7 A;  2F6F A;  3V0D A;  3RGQ A;  4KYQ A;  3RGO A;  3ZMP A;  1XRI A;  3F41 A;  1FPR A;  3QCG A;  2MBC A;  4H1O A;  4GFU A;  5AWX A;  4QUM A;  5BZZ A;  3I36 A;  1G1G A;  2VEW A;  1C88 A;  1G4U S;  3ZV2 A;  2I75 A;  1I57 A;  5K23 A;  2F6Y A;  3S3E A;  4KYR A;  1U24 A;  4HJQ A;  1PYN A;  5K24 A;  5K9V A;  4GRZ A;  1WAX A;  5BX1 A;  3AWG A;  5GTJ A;  3OLR A;  2J16 B;  2OC3 A;  2F70 A;  4RKK A;  1FPZ A;  2B4O A;  5KA1 A;  4RI5 A;  1OEU A;  5HDE A;  2P4D A;  3S3K A;  1BZJ A;  2OUD A;  1LQF A;  1C85 A;  3LJ8 A;  1Q1M A;  2VEX A;  4OHE A;  2HC1 A;  3F9B A;  5LXQ B;  1T49 A;  1C84 A;  2H02 A;  5IBS A;  2B4U A;  3EAX A;  2NT2 A;  4D3Q A;  5EHP A;  1Q6S A;  2JJD A;  1XBO A;  2M3V A;  3QCF A;  4QUN A;  3QCJ A;  2CM8 A;  5K9W A;  3F99 A;  3D1Q A;  5KAB A;  2QDM A;  1WRM A;  1GWZ A;  3SME A;  1RXD A;  5I6V A;  4BPC A;  1PTU A;  3QCC A;  2PA5 A;  1YWF A;  4GWF A;  3H2X A;  4J51 A;  5KA8 A;  1PTV A;  2CNE A;  4QAP A;  3QCI A;  1A5Y A;  3ZM0 A;  2I6O A;  2BGD A;  2NTA A;  5M43 A;  3D1O A;  4JNB A;  4PVG A;  2BV5 A;  3B7O A;  2HC2 A;  4OHH A;  4YAA A;  2C7S A;  3SR9 A;  4QBE A;  1NWE A;  3M4U A;  3BRH A;  2H4V A;  2QBP A;  1AAX A;  4RDD A;  2HNP A;  2ZN7 A;  3QCH A;  4GE5 A;  2G6Z A;  1OHE A;  1L8G A;  1YTW A;  1BZH A;  5KA9 A;  4ICZ A;  3S4E A;  2BZL A;  1WCH A;  1C87 A;  1OHC A;  1FQ1 A;  1RPM A;  2I6J A;  2F6W A;  1EEO A;  2I6I A;  5KA0 A;  2CNF A;  1J4X A;  2Y96 A;  1PTT A;  1PTY A;  1JF7 A;  2QDP A;  3V0J A;  4ERC A;  2NLK A;  2B4P A;  2HVL A;  5KA7 A;  1PA9 A;  2H03 A;  3U96 A;  1V3A A;  3N0A A;  4R0S A;  5J8R A;  1OEV A;  1I9S A;  1LAR A;  3MOW A;  2CMB A;  1ONZ A;  2B3O A;  3CM3 A;  4QBW A;  3V0G A;  4WU3 A;  1KAV A;  2J16 A;  2SHP A; 
#chains in the Genus database with same CATH topology
 2OZ5 A;  1T48 A;  2I6P A;  1BZC A;  4QF5 A;  3QCM A;  4CVK A;  5KA4 A;  4WU2 A;  1YTS A;  4OHI A;  1PA1 A;  3EB1 A;  1W78 A;  4WOH A;  3I7Z A;  4BJO A;  2G59 A;  4Y2E A;  1U26 A;  3NME A;  4RI4 A;  1MKP A;  1D5R A;  2B4S A;  1GG4 A;  2B49 A;  1LYV A;  2QCT A;  2I1Y A;  3F81 A;  4Z6B A;  3OMH A;  2JFG A;  2F6Z A;  1ECV A;  2RF6 A;  2AZR A;  4JBC A;  3AWE A;  2CNH A;  1JLN A;  2JFH A;  3I80 A;  1YFO A;  5A5E A;  2GCA A;  5A5F A;  3QCE A;  1ZCL A;  1OES A;  2A8B A;  3O3L A;  2HXP A;  2GCB A;  1OET A;  4GFV A;  1E0D A;  1QXK A;  2E0T A;  4PYH A;  4WTY A;  4QAH A;  4GE2 A;  4RH5 A;  2H4K A;  1X24 A;  3CWE A;  1G7F A;  3ZM2 A;  3BM8 A;  3MMJ A;  2A3K A;  3BLT A;  2Q47 A;  5IBM A;  2I5X A;  2I4G A;  1M3G A;  2QEP A;  4D3R A;  4GS0 A;  1Q6P A;  4RHG A;  3ZM3 A;  4DGX A;  2CFV A;  2NZ6 A;  2WGP A;  2F6V A;  2UUP A;  3QKP A;  2CJZ A;  2CM2 A;  3V0H A;  1JBV A;  1R6H A;  4MBB A;  3A5J A;  2VOR A;  3V0F A;  3A5K A;  2F6T A;  3ZM1 A;  5KAD A;  2I6M A;  2VEV A;  3S4O A;  3ZMQ A;  4D3P A;  1YTN A;  5KA3 A;  1P3D A;  4NWF A;  4OHD A;  4I8N A;  2HB1 A;  3V0E A;  2PBN A;  2P6X A;  3EU0 A;  1YPT A;  2Y66 A;  1NNY A;  1OEO X;  2QBS A;  2I4H A;  1G1F A;  2GJT A;  2WTZ A;  4B04 A;  3PYZ A;  2F00 A;  1YGU A;  1KAK A;  3RO1 A;  2VEU A;  5KA2 A;  2ESB A;  4ZI4 A;  2IMG A;  2FJM A;  4JMJ A;  4HRF A;  5KAC A;  2AHS A;  1XXP A;  1YN9 A;  1VHR A;  1EEN A;  4HJP A;  4DGP A;  4YR8 B;  3QCB A;  2HCM A;  3V0I A;  1OHD A;  2QCJ A;  4OHL A;  2I4E A;  2AM2 A;  2ZMM A;  2GP0 A;  1Q6J A;  2VTD A;  2XPC A;  3QKQ A;  1E8C A;  2QBR A;  5BZX A;  3MVN A;  2H04 A;  2I3U A;  1NO6 A;  1G1H A;  4S0G A;  1C83 A;  3QCK A;  1U25 A;  2OOQ A;  3GXG A;  2GWO A;  1P15 A;  4NYH A;  3HN7 A;  3D42 A;  2NV5 A;  3O5X A;  2YDU A;  2HNQ A;  1Q6N A;  4Y14 A;  3F9A A;  3PS5 A;  3O4U A;  1C86 A;  2QBQ A;  2I42 A;  1ZZW A;  1NL9 A;  4CVL A;  1XXV A;  4NWG A;  4GE6 A;  1XM2 A;  2FJN A;  4C13 A;  3EZZ A;  2H4G A;  3QCZ A;  3D44 A;  2QDC A;  1YZ4 A;  1I9T A;  3GXH A;  4IKC A;  5BUG A;  1L8K A;  1NWL A;  5K25 A;  3LK7 A;  2NT7 A;  4RH9 A;  1GQQ A;  2BIJ A;  4KI9 A;  5K22 A;  2FH7 A;  2C46 A;  2F71 A;  1YGR A;  2BGE A;  2DXP A;  2Y67 A;  4R0T A;  2Y2F A;  1PH0 A;  1FGS A;  4UAG A;  1ZCK A;  3O4T A;  3O4S A;  4NND A;  3QCN A;  3D9C A;  2PQ5 A;  5KAA A;  3EMU A;  1Q6M A;  3RZ2 A;  3S3F A;  1ONY A;  2AM1 A;  2PSZ A;  4R30 A;  4ZN5 A;  2CMC A;  5EHR A;  3MOZ A;  1ZC0 A;  2CMA A;  2CNI A;  1QZ0 A;  2Q05 A;  3S3H A;  4AZ1 A;  3NRS A;  1Q6T A;  2R0B A;  1G4W R;  2CNG A;  4JMK A;  2VEY A;  3QCD A;  3QCL A;  3ZL8 A;  1SUG A;  1GFY A;  3BLU A;  2J17 A;  2F46 A;  1OEM X;  4NX8 A;  4GRY A;  4H34 A;  3UAG A;  2CM7 A;  2PT0 A;  3D1H A;  1PXH A;  4ZRT A;  5MMZ B;  2B07 A;  2PI7 A;  1G7G A;  4TVV A;  2I3R A;  2CM3 A;  2HY3 A;  1T4J A;  1W7K A;  3AWF A;  1NZ7 A;  2F6F A;  3V0D A;  3RGQ A;  4KYQ A;  3RGO A;  2Y68 A;  2XJA A;  3ZMP A;  1XRI A;  3F41 A;  1FPR A;  3QCG A;  2MBC A;  4H1O A;  4GFU A;  5AWX A;  4QUM A;  5BZZ A;  3I36 A;  1G1G A;  4HV4 A;  2VEW A;  1C88 A;  1G4U S;  3ZV2 A;  2I75 A;  1I57 A;  5K23 A;  2GC5 A;  2F6Y A;  3S3E A;  4KYR A;  1U24 A;  4HJQ A;  1PYN A;  5K24 A;  5K9V A;  4GRZ A;  1WAX A;  5BX1 A;  3AWG A;  5GTJ A;  3OLR A;  2J16 B;  2OC3 A;  2F70 A;  4RKK A;  1FPZ A;  2B4O A;  5KA1 A;  4RI5 A;  1OEU A;  5HDE A;  2P4D A;  3S3K A;  1BZJ A;  4QDI A;  2OUD A;  1LQF A;  1C85 A;  3LJ8 A;  1O5Z A;  2VOS A;  1Q1M A;  2VEX A;  4OHE A;  2HC1 A;  3F9B A;  5LXQ B;  1T49 A;  1C84 A;  2H02 A;  5IBS A;  2B4U A;  3EAX A;  2NT2 A;  4D3Q A;  5EHP A;  1Q6S A;  2JJD A;  1XBO A;  2M3V A;  3QCF A;  4QUN A;  3QCJ A;  2CM8 A;  5K9W A;  3F99 A;  3D1Q A;  5KAB A;  2QDM A;  1WRM A;  1GWZ A;  3SME A;  2UAG A;  3ZM6 A;  1RXD A;  5I6V A;  4BPC A;  1PTU A;  2UUO A;  2PA5 A;  3QCC A;  1YWF A;  4GWF A;  3H2X A;  1UAG A;  4J51 A;  5KA8 A;  1PTV A;  2CNE A;  4QAP A;  3QCI A;  1A5Y A;  3ZM0 A;  2I6O A;  2BGD A;  2NTA A;  1P31 A;  5M43 A;  3D1O A;  4JNB A;  4PVG A;  2BV5 A;  2WJP A;  3B7O A;  2Y1O A;  2HC2 A;  4OHH A;  2VTE A;  4YAA A;  2X5O A;  2C7S A;  3SR9 A;  4QBE A;  1NWE A;  3M4U A;  4BUB A;  3BRH A;  3ZM5 A;  2H4V A;  2QBP A;  1AAX A;  4RDD A;  2HNP A;  2ZN7 A;  3QCH A;  4GE5 A;  3N2A A;  2G6Z A;  1OHE A;  1L8G A;  4CVM A;  1YTW A;  1J6U A;  1GQY A;  1BZH A;  5KA9 A;  1EEH A;  4ICZ A;  3S4E A;  1JBW A;  2BZL A;  1WCH A;  1C87 A;  1OHC A;  1FQ1 A;  1RPM A;  2I6J A;  2F6W A;  1EEO A;  2I6I A;  5KA0 A;  2CNF A;  1J4X A;  2Y96 A;  1PTT A;  1PTY A;  1JF7 A;  2QDP A;  3V0J A;  4ERC A;  2NLK A;  2B4P A;  2HVL A;  2GC6 A;  2JFF A;  5KA7 A;  4ZIY A;  1PA9 A;  2H03 A;  4C12 A;  3U96 A;  1V3A A;  3N0A A;  4R0S A;  5J8R A;  1OEV A;  4BUC A;  1I9S A;  1LAR A;  3MOW A;  2CMB A;  1ONZ A;  2B3O A;  3CM3 A;  4QBW A;  3V0G A;  4WU3 A;  1KAV A;  2J16 A;  2SHP A; 
#chains in the Genus database with same CATH homology
 2OZ5 A;  1T48 A;  2I6P A;  1BZC A;  3QCM A;  5KA4 A;  4WU2 A;  1YTS A;  4OHI A;  1PA1 A;  3EB1 A;  4WOH A;  3I7Z A;  4BJO A;  2G59 A;  4Y2E A;  1U26 A;  3NME A;  4RI4 A;  1MKP A;  1D5R A;  2B4S A;  2B49 A;  1LYV A;  2QCT A;  2I1Y A;  3F81 A;  4Z6B A;  3OMH A;  2F6Z A;  1ECV A;  2RF6 A;  2AZR A;  4JBC A;  3AWE A;  2CNH A;  1JLN A;  3I80 A;  1YFO A;  3QCE A;  1ZCL A;  1OES A;  2A8B A;  3O3L A;  2HXP A;  1OET A;  4GFV A;  1QXK A;  2E0T A;  4PYH A;  4WTY A;  4QAH A;  4GE2 A;  4RH5 A;  2H4K A;  1X24 A;  3CWE A;  1G7F A;  3ZM2 A;  3BM8 A;  3MMJ A;  2A3K A;  3BLT A;  2Q47 A;  5IBM A;  2I5X A;  2I4G A;  1M3G A;  2QEP A;  4D3R A;  4GS0 A;  1Q6P A;  4RHG A;  3ZM3 A;  4DGX A;  2CFV A;  2NZ6 A;  2WGP A;  2F6V A;  3QKP A;  2CJZ A;  2CM2 A;  3V0H A;  4MBB A;  1R6H A;  3A5J A;  3V0F A;  3A5K A;  2F6T A;  3ZM1 A;  5KAD A;  2I6M A;  2VEV A;  3S4O A;  3ZMQ A;  4D3P A;  1YTN A;  5KA3 A;  4NWF A;  4OHD A;  4I8N A;  2HB1 A;  3V0E A;  2PBN A;  2P6X A;  3EU0 A;  1YPT A;  1NNY A;  1OEO X;  2QBS A;  2I4H A;  1G1F A;  2GJT A;  4B04 A;  1YGU A;  1KAK A;  3RO1 A;  2VEU A;  5KA2 A;  2ESB A;  4ZI4 A;  2IMG A;  2FJM A;  4JMJ A;  4HRF A;  5KAC A;  2AHS A;  1XXP A;  1YN9 A;  1VHR A;  1EEN A;  4HJP A;  4DGP A;  4YR8 B;  3QCB A;  2HCM A;  3V0I A;  1OHD A;  2QCJ A;  4OHL A;  2I4E A;  2ZMM A;  2GP0 A;  1Q6J A;  3QKQ A;  2QBR A;  5BZX A;  2H04 A;  2I3U A;  1NO6 A;  1G1H A;  4S0G A;  1C83 A;  3QCK A;  1U25 A;  2OOQ A;  3GXG A;  2GWO A;  1P15 A;  4NYH A;  3D42 A;  2NV5 A;  3O5X A;  2YDU A;  2HNQ A;  1Q6N A;  4Y14 A;  3F9A A;  3PS5 A;  3O4U A;  1C86 A;  2QBQ A;  2I42 A;  1ZZW A;  1NL9 A;  1XXV A;  4NWG A;  4GE6 A;  1XM2 A;  2FJN A;  3EZZ A;  2H4G A;  3D44 A;  2QDC A;  1YZ4 A;  1I9T A;  3GXH A;  4IKC A;  5BUG A;  1L8K A;  1NWL A;  5K25 A;  2NT7 A;  4RH9 A;  2BIJ A;  4KI9 A;  5K22 A;  2FH7 A;  2C46 A;  2F71 A;  1YGR A;  2BGE A;  2DXP A;  4R0T A;  2Y2F A;  1PH0 A;  1ZCK A;  3O4T A;  3O4S A;  4NND A;  3QCN A;  3D9C A;  2PQ5 A;  5KAA A;  3EMU A;  1Q6M A;  3RZ2 A;  3S3F A;  1ONY A;  4ZN5 A;  2PSZ A;  4R30 A;  2CMC A;  5EHR A;  3MOZ A;  1ZC0 A;  2CMA A;  2CNI A;  1QZ0 A;  2Q05 A;  3S3H A;  4AZ1 A;  1Q6T A;  2R0B A;  1G4W R;  2CNG A;  4JMK A;  2VEY A;  3QCD A;  3QCL A;  1SUG A;  1GFY A;  3BLU A;  2J17 A;  2F46 A;  1OEM X;  4NX8 A;  4GRY A;  4H34 A;  2CM7 A;  2PT0 A;  3D1H A;  1PXH A;  4ZRT A;  5MMZ B;  2B07 A;  2PI7 A;  1G7G A;  4TVV A;  2I3R A;  2CM3 A;  2HY3 A;  1T4J A;  3AWF A;  1NZ7 A;  2F6F A;  3V0D A;  3RGQ A;  4KYQ A;  3RGO A;  3ZMP A;  1XRI A;  3F41 A;  1FPR A;  3QCG A;  2MBC A;  4H1O A;  4GFU A;  5AWX A;  4QUM A;  5BZZ A;  3I36 A;  1G1G A;  2VEW A;  1C88 A;  1G4U S;  3ZV2 A;  2I75 A;  1I57 A;  5K23 A;  2F6Y A;  3S3E A;  4KYR A;  1U24 A;  4HJQ A;  1PYN A;  5K24 A;  5K9V A;  4GRZ A;  1WAX A;  5BX1 A;  3AWG A;  5GTJ A;  3OLR A;  2J16 B;  2OC3 A;  2F70 A;  4RKK A;  1FPZ A;  2B4O A;  5KA1 A;  4RI5 A;  1OEU A;  5HDE A;  2P4D A;  3S3K A;  1BZJ A;  2OUD A;  1LQF A;  1C85 A;  3LJ8 A;  1Q1M A;  2VEX A;  4OHE A;  2HC1 A;  3F9B A;  5LXQ B;  1T49 A;  1C84 A;  2H02 A;  5IBS A;  2B4U A;  3EAX A;  2NT2 A;  4D3Q A;  5EHP A;  1Q6S A;  2JJD A;  1XBO A;  2M3V A;  3QCF A;  4QUN A;  3QCJ A;  2CM8 A;  5K9W A;  3F99 A;  3D1Q A;  5KAB A;  2QDM A;  1WRM A;  1GWZ A;  3SME A;  1RXD A;  5I6V A;  4BPC A;  1PTU A;  3QCC A;  2PA5 A;  1YWF A;  4GWF A;  3H2X A;  4J51 A;  5KA8 A;  1PTV A;  2CNE A;  4QAP A;  3QCI A;  1A5Y A;  3ZM0 A;  2I6O A;  2BGD A;  2NTA A;  5M43 A;  3D1O A;  4JNB A;  4PVG A;  2BV5 A;  3B7O A;  2HC2 A;  4OHH A;  4YAA A;  2C7S A;  3SR9 A;  4QBE A;  1NWE A;  3M4U A;  3BRH A;  2H4V A;  2QBP A;  1AAX A;  4RDD A;  2HNP A;  2ZN7 A;  3QCH A;  4GE5 A;  2G6Z A;  1OHE A;  1L8G A;  1YTW A;  1BZH A;  5KA9 A;  4ICZ A;  3S4E A;  2BZL A;  1WCH A;  1C87 A;  1OHC A;  1FQ1 A;  1RPM A;  2I6J A;  2F6W A;  1EEO A;  2I6I A;  5KA0 A;  2CNF A;  1J4X A;  2Y96 A;  1PTT A;  1PTY A;  1JF7 A;  2QDP A;  3V0J A;  4ERC A;  2NLK A;  2B4P A;  2HVL A;  5KA7 A;  1PA9 A;  2H03 A;  3U96 A;  1V3A A;  3N0A A;  4R0S A;  5J8R A;  1OEV A;  1I9S A;  1LAR A;  3MOW A;  2CMB A;  1ONZ A;  2B3O A;  3CM3 A;  4QBW A;  3V0G A;  4WU3 A;  1KAV A;  2J16 A;  2SHP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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