1G1FA

Crystal structure of protein tyrosine phosphatase 1b complexed with a tri-phosphorylated peptide (rdi(ptr)etd(ptr)(ptr)rk) from the insulin receptor kinase
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHASAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase, signaling protein
source organism Homo sapiens
molecule keywords PROTEIN TYROSINE PHOSPHATASE 1B
total genus 98
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1g1fA00
1NWEA 2HXPA 1L8KA 2WGPA 5KA8A 3ZV2A 2HC1A 2I3RA 3QCMA 2BGEA 4D3PA 4JBCA 5KA4A 1ONYA 3F9BA 2VEUA 1G7FA 4PYHA 4DGPA 1Q6MA 4GS0A 1JLNA 3QCNA 1XRIA 5EHRA 5M43A 1YGUA 1LARA 4RI4A 2QBSA 1NO6A 1SUGA 1OHEA 3EB1A 4OHEA 1FQ1A 3ZM1A 4GRZA 3S3KA 1L8GA 3QCDA 5KAAA 2PT0A 2QDMA 3O5XA 4NYHA 3S3FA 3OLRA 2ZMMA 4QUNA 1OEVA 1XXPA 2AHSA 3RZ2A 2BIJA 3EZZA 4TVVA 2PBNA 3M4UA 1AAXA 2PSZA 2VEWA 1KAVA 4JMJA 3BRHA 1XBOA 2I6OA 5IBSA 2F6VA 2M3VA 1KAKA 4RDDA 4WU2A 1BZHA 3F99A 3V0GA 5BUGA 2QBQA 4GWFA 2B4UA 4AZ1A 1J4XA 3F9AA 3V0JA 1T48A 1R6HA 4BPCA 1JF7A 3A5KA 1ZZWA 1RXDA 1PA9A 3EMUA 1YPTA 4H1OA 2FJMA 3RGQA 3BLUA 5KADA 1GWZA 1EENA 2F71A 3O3LA 1G1HA 1YFOA 4J51A 3ZM0A 2PQ5A 2FH7A 2J17A 2H04A 3H2XA 2I6MA 1ECVA 3GXHA 4ZN5A 3QCKA 2VEYA 3CM3A 3SMEA 3CWEA 1BZCA 1PH0A 1U24A 2CMCA 2P4DA 3RGOA 3I36A 4QUMA 1XXVA 5EHPA 2YDUA 2H4VA 2G59A 2F46A 4KYRA 1BZJA 1YTWA 4NWGA 1Q6JA 4Y2EA 4H34A 1VHRA 2CNEA 2F6ZA 3QCCA 4GFVA 1EEOA 3V0IA 2GP0A 2QDCA 1OESA 4RI5A 3B7OA 1D5RA 2NV5A 1OETA 1QZ0A 4WU3A 3ZMPA 4D3RA 3V0HA 3D1OA 1G4US 1PA1A 1U25A 5K9WA 3QKQA 2ZN7A 2JJDA 5BZXA 4R0SA 5HDEA 2H03A 2NTAA 2Q47A 3BM8A 1OHCA 5K9VA 1OEOX 1G7GA 3S3EA 5KA0A 2I42A 2MBCA 2QCTA 2A8BA 4OHLA 3LJ8A 3O4UA 2P6XA 3D1HA 2I6PA 2CNHA 5KACA 3S4OA 1PTYA 4JNBA 1QXKA 3OMHA 4BJOA 1M3GA 1NL9A 1RPMA 1P15A 1XM2A 4HJPA 1G4WR 2B3OA 2HC2A 1LYVA 1FPZA 4OHHA 5KA1A 4WOHA 1ZCLA 4GFUA 1LQFA 1Q6NA 4OHIA 4YR8B 1YTNA 1ZC0A 4RH5A 4QAPA 2CNIA 3MOWA 3MOZA 3QCLA 2NT2A 2NT7A 2A3KA 3QCHA 5I6VA 2IMGA 2CNFA 1ONZA 2HNQA 2PI7A 4JMKA 3BLTA 5BZZA 2F6TA 5KABA 2H4GA 3AWFA 4MBBA 3I80A 2BGDA 2GWOA 2QBRA 3MMJA 5LXQB 2B49A 3V0DA 2QEPA 2I3UA 2CM7A 1C83A 2F6FA 1A5YA 4NWFA 1C85A 2OC3A 1NWLA 4KI9A 5K24A 3QCGA 2B4PA 3A5JA 2B07A 2I1YA 4GRYA 2B4OA 1Q6SA 1FPRA 4RKKA 2HVLA 2RF6A 1PTVA 5J8RA 5KA9A 2QCJA 2NZ6A 2GJTA 1PTTA 2F6YA 5BX1A 1Q1MA 1V3AA 1PYNA 1MKPA 1U26A 2CM8A 3D1QA 2QDPA 3N0AA 2QBPA 4ZRTA 2J16A 5K22A 2I5XA 4R0TA 4Z6BA 1YTSA 2VEXA 5K23A 3SR9A 4QAHA 4S0GA 3QCBA 3F41A 1C86A 1I57A 4ZI4A 5KA3A 1ZCKA 5MMZB 3QKPA 3S4EA 1G1GA 3F81A 4Y14A 2CJZA 4RH9A 1C88A 3ZM3A 1G1FA 2HY3A 2SHPA 2F70A 2I4EA 4DGXA 2ESBA 3D44A 4NNDA 3NMEA 1YZ4A 2CNGA 3GXGA 4I8NA 2AZRA 4PVGA 2CM3A 3O4TA 5AWXA 2NLKA 2HB1A 2R0BA 5KA2A 4GE6A 3RO1A 2G6ZA 1GFYA 1T4JA 1I9SA 2H02A 1OEUA 3D42A 3EU0A 1YWFA 2OUDA 2B4SA 1OEMX 5KA7A 2I6JA 3QCIA 3ZMQA 1WCHA 3D9CA 1NZ7A 2E0TA 3O4SA 1C87A 1PXHA 1T49A 2FJNA 2Q05A 2BV5A 5IBMA 4YAAA 2HNPA 4KYQA 2OZ5A 4WTYA 2I4GA 1I9TA 1Q6TA 3EAXA 2J16B 4HJQA 4R30A 5K25A 1YN9A 2CMBA 2CMAA 4ERCA 2OOQA 3PS5A 2DXPA 2F6WA 1C84A 4ICZA 1NNYA 4NX8A 4HRFA 3AWEA 3QCJA 4RHGA 2H4KA 3AWGA 3I7ZA 2I6IA 3U96A 5GTJA 2Y2FA 2I75A 2VEVA 2CFVA 2Y96A 2C7SA 4D3QA 2I4HA 4GE5A 2HCMA 4QBEA 2BZLA 2CM2A 1Q6PA 1YGRA 4QBWA 2PA5A 3QCEA 3V0EA 1X24A 3S3HA 3ZM2A 1PTUA 3V0FA 1WRMA 4OHDA 4B04A 1WAXA 3QCFA 4IKCA 4GE2A 2C46A 1OHDA
chains in the Genus database with same CATH superfamily
1NWEA 2HXPA 1L8KA 2WGPA 5KA8A 3ZV2A 2HC1A 2I3RA 2WJPA 3QCMA 2BGEA 4D3PA 4JBCA 5KA4A 1ONYA 3F9BA 2VEUA 1G7FA 4PYHA 4DGPA 1Q6MA 4GS0A 1JLNA 2Y67A 3QCNA 1W7KA 1XRIA 5EHRA 5M43A 1YGUA 1LARA 4RI4A 2QBSA 1NO6A 5A5FA 1SUGA 1OHEA 1JBWA 3EB1A 4OHEA 1FQ1A 3ZM1A 2VTEA 4GRZA 3S3KA 1L8GA 3QCDA 5KAAA 2PT0A 2QDMA 3O5XA 4NYHA 3S3FA 2XJAA 3OLRA 2ZMMA 4QUNA 1GG4A 1OEVA 1XXPA 2AHSA 3RZ2A 2BIJA 3EZZA 4TVVA 2PBNA 3M4UA 1AAXA 2PSZA 2VEWA 1KAVA 4JMJA 3BRHA 3ZM6A 1XBOA 2I6OA 5IBSA 2F6VA 2M3VA 1KAKA 4RDDA 4WU2A 1BZHA 3F99A 3V0GA 5BUGA 2QBQA 4GWFA 2B4UA 3LK7A 4AZ1A 1J4XA 3F9AA 3V0JA 1T48A 2WTZA 1R6HA 4BPCA 1JF7A 3A5KA 1ZZWA 1RXDA 1PA9A 3EMUA 1YPTA 4H1OA 2FJMA 3RGQA 3BLUA 5KADA 1GWZA 3HN7A 1EENA 2F71A 3O3LA 1G1HA 1YFOA 4J51A 3ZM0A 2PQ5A 2FH7A 2J17A 3MVNA 2H04A 3H2XA 2I6MA 1ECVA 3GXHA 4ZN5A 3QCKA 2VEYA 3CM3A 3SMEA 3CWEA 1BZCA 1PH0A 1U24A 2CMCA 2P4DA 3RGOA 3I36A 4BUBA 4QUMA 1XXVA 5EHPA 2YDUA 1GQQA 2H4VA 2G59A 2F46A 4KYRA 1BZJA 1YTWA 4NWGA 1Q6JA 4Y2EA 4H34A 2AM1A 1VHRA 2CNEA 2F6ZA 3QCCA 4GFVA 1EEOA 2JFFA 3V0IA 2GP0A 2QDCA 1OESA 4RI5A 3B7OA 1D5RA 2NV5A 2JFGA 1OETA 1QZ0A 4WU3A 3ZMPA 4D3RA 3V0HA 3D1OA 1G4US 1PA1A 1U25A 5K9WA 3QKQA 2ZN7A 2JJDA 5BZXA 4R0SA 5HDEA 2H03A 2NTAA 2Q47A 3BM8A 1OHCA 5K9VA 1OEOX 1G7GA 3S3EA 5KA0A 2I42A 2MBCA 2QCTA 2A8BA 2UUPA 4OHLA 3ZM5A 3LJ8A 3O4UA 2P6XA 3D1HA 2I6PA 2CNHA 5KACA 3S4OA 1PTYA 4JNBA 1QXKA 3OMHA 4BJOA 1M3GA 1NL9A 1RPMA 2GC5A 1P15A 1XM2A 4HJPA 1G4WR 2B3OA 2AM2A 2HC2A 1LYVA 1FPZA 4OHHA 5KA1A 4WOHA 1ZCLA 4GFUA 1LQFA 1Q6NA 4OHIA 4YR8B 1YTNA 1ZC0A 4RH5A 4QAPA 2CNIA 3MOWA 3MOZA 2NT2A 2NT7A 2A3KA 3QCLA 3QCHA 1UAGA 2IMGA 5I6VA 2CNFA 1ONZA 2HNQA 2PI7A 4JMKA 3BLTA 5BZZA 2F6TA 5KABA 2H4GA 3AWFA 4MBBA 3I80A 2BGDA 2GWOA 2QBRA 3MMJA 5LXQB 2B49A 3V0DA 4CVLA 2JFHA 2QEPA 2I3UA 2CM7A 1C83A 2F6FA 1A5YA 4NWFA 1C85A 2OC3A 1NWLA 4KI9A 5K24A 3QCGA 2B4PA 3A5JA 2B07A 2I1YA 4GRYA 2B4OA 1Q6SA 1FPRA 2VORA 4RKKA 2HVLA 2RF6A 1PTVA 5J8RA 5KA9A 2QCJA 4BUCA 2NZ6A 2Y66A 2GJTA 1PTTA 2F6YA 5BX1A 1JBVA 1Q1MA 2UAGA 1V3AA 1PYNA 1MKPA 1U26A 2CM8A 2VOSA 3D1QA 2QDPA 3N0AA 2QBPA 4CVKA 4ZRTA 2J16A 5K22A 2I5XA 4R0TA 4Z6BA 1YTSA 3NRSA 2VEXA 4C13A 3UAGA 5K23A 4UAGA 3SR9A 4QAHA 4S0GA 3QCBA 3F41A 1C86A 1GQYA 1EEHA 1I57A 4ZI4A 4CVMA 5KA3A 1ZCKA 5MMZB 3QKPA 1P31A 3S4EA 1G1GA 3F81A 4Y14A 2GCBA 2CJZA 4RH9A 1C88A 1O5ZA 3ZM3A 1G1FA 2HY3A 1FGSA 2SHPA 2F70A 2I4EA 4DGXA 2ESBA 3D44A 4NNDA 3NMEA 1YZ4A 2CNGA 3GXGA 4I8NA 2AZRA 4C12A 4PVGA 2CM3A 3O4TA 5AWXA 2NLKA 2HB1A 2R0BA 5KA2A 4GE6A 3RO1A 2G6ZA 1GFYA 1T4JA 1I9SA 2H02A 1OEUA 2GCAA 1P3DA 1W78A 3D42A 3EU0A 1YWFA 2OUDA 2B4SA 1OEMX 5KA7A 1E0DA 2I6JA 3QCIA 3ZMQA 1WCHA 2Y68A 3D9CA 1NZ7A 2E0TA 3O4SA 1C87A 1PXHA 1T49A 2FJNA 2Q05A 2BV5A 5IBMA 3PYZA 4YAAA 2HNPA 4KYQA 2OZ5A 4WTYA 2I4GA 1I9TA 1Q6TA 3EAXA 2J16B 4HJQA 4R30A 2Y1OA 5K25A 1YN9A 2CMBA 2CMAA 4ERCA 2OOQA 3PS5A 2DXPA 3N2AA 2F6WA 1C84A 4ICZA 1NNYA 4NX8A 4HRFA 3AWEA 3QCJA 4RHGA 1J6UA 2H4KA 1E8CA 3AWGA 3QCZA 3I7ZA 2I6IA 3U96A 4QF5A 5GTJA 2Y2FA 2I75A 2VTDA 2VEVA 4ZIYA 2CFVA 2Y96A 2XPCA 2C7SA 4D3QA 2I4HA 4GE5A 2HCMA 5A5EA 4QBEA 2BZLA 2CM2A 1Q6PA 2X5OA 1YGRA 4QBWA 4QDIA 2PA5A 3QCEA 3V0EA 1X24A 2UUOA 4HV4A 2GC6A 3S3HA 3ZM2A 3ZL8A 1PTUA 3V0FA 1WRMA 4OHDA 4B04A 1WAXA 3QCFA 4IKCA 4GE2A 2C46A 2F00A 1OHDA
chains in the Genus database with same CATH topology
1NWEA 2HXPA 1L8KA 2WGPA 5KA8A 3ZV2A 2HC1A 2I3RA 3QCMA 2BGEA 4D3PA 4JBCA 5KA4A 1ONYA 3F9BA 2VEUA 1G7FA 4PYHA 4DGPA 1Q6MA 4GS0A 1JLNA 3QCNA 1XRIA 5EHRA 5M43A 1YGUA 1LARA 4RI4A 2QBSA 1NO6A 1SUGA 1OHEA 3EB1A 4OHEA 1FQ1A 3ZM1A 4GRZA 3S3KA 1L8GA 3QCDA 5KAAA 2PT0A 2QDMA 3O5XA 4NYHA 3S3FA 3OLRA 2ZMMA 4QUNA 1OEVA 1XXPA 2AHSA 3RZ2A 2BIJA 3EZZA 4TVVA 2PBNA 3M4UA 1AAXA 2PSZA 2VEWA 1KAVA 4JMJA 3BRHA 1XBOA 2I6OA 5IBSA 2F6VA 2M3VA 1KAKA 4RDDA 4WU2A 1BZHA 3F99A 3V0GA 5BUGA 2QBQA 4GWFA 2B4UA 4AZ1A 1J4XA 3F9AA 3V0JA 1T48A 1R6HA 4BPCA 1JF7A 3A5KA 1ZZWA 1RXDA 1PA9A 3EMUA 1YPTA 4H1OA 2FJMA 3RGQA 3BLUA 5KADA 1GWZA 1EENA 2F71A 3O3LA 1G1HA 1YFOA 4J51A 3ZM0A 2PQ5A 2FH7A 2J17A 2H04A 3H2XA 2I6MA 1ECVA 3GXHA 4ZN5A 3QCKA 2VEYA 3CM3A 3SMEA 3CWEA 1BZCA 1PH0A 1U24A 2CMCA 2P4DA 3RGOA 3I36A 4QUMA 1XXVA 5EHPA 2YDUA 2H4VA 2G59A 2F46A 4KYRA 1BZJA 1YTWA 4NWGA 1Q6JA 4Y2EA 4H34A 1VHRA 2CNEA 2F6ZA 3QCCA 4GFVA 1EEOA 3V0IA 2GP0A 2QDCA 1OESA 4RI5A 3B7OA 1D5RA 2NV5A 1OETA 1QZ0A 4WU3A 3ZMPA 4D3RA 3V0HA 3D1OA 1G4US 1PA1A 1U25A 5K9WA 3QKQA 2ZN7A 2JJDA 5BZXA 4R0SA 5HDEA 2H03A 2NTAA 2Q47A 3BM8A 1OHCA 5K9VA 1OEOX 1G7GA 3S3EA 5KA0A 2I42A 2MBCA 2QCTA 2A8BA 4OHLA 3LJ8A 3O4UA 2P6XA 3D1HA 2I6PA 2CNHA 5KACA 3S4OA 1PTYA 4JNBA 1QXKA 3OMHA 4BJOA 1M3GA 1NL9A 1RPMA 1P15A 1XM2A 4HJPA 1G4WR 2B3OA 2HC2A 1LYVA 1FPZA 4OHHA 5KA1A 4WOHA 1ZCLA 4GFUA 1LQFA 1Q6NA 4OHIA 4YR8B 1YTNA 1ZC0A 4RH5A 4QAPA 2CNIA 3MOWA 3MOZA 3QCLA 2NT2A 2NT7A 2A3KA 3QCHA 5I6VA 2IMGA 2CNFA 1ONZA 2HNQA 2PI7A 4JMKA 3BLTA 5BZZA 2F6TA 5KABA 2H4GA 3AWFA 4MBBA 3I80A 2BGDA 2GWOA 2QBRA 3MMJA 5LXQB 2B49A 3V0DA 2QEPA 2I3UA 2CM7A 1C83A 2F6FA 1A5YA 4NWFA 1C85A 2OC3A 1NWLA 4KI9A 5K24A 3QCGA 2B4PA 3A5JA 2B07A 2I1YA 4GRYA 2B4OA 1Q6SA 1FPRA 4RKKA 2HVLA 2RF6A 1PTVA 5J8RA 5KA9A 2QCJA 2NZ6A 2GJTA 1PTTA 2F6YA 5BX1A 1Q1MA 1V3AA 1PYNA 1MKPA 1U26A 2CM8A 3D1QA 2QDPA 3N0AA 2QBPA 4ZRTA 2J16A 5K22A 2I5XA 4R0TA 4Z6BA 1YTSA 2VEXA 5K23A 3SR9A 4QAHA 4S0GA 3QCBA 3F41A 1C86A 1I57A 4ZI4A 5KA3A 1ZCKA 5MMZB 3QKPA 3S4EA 1G1GA 3F81A 4Y14A 2CJZA 4RH9A 1C88A 3ZM3A 1G1FA 2HY3A 2SHPA 2F70A 2I4EA 4DGXA 2ESBA 3D44A 4NNDA 3NMEA 1YZ4A 2CNGA 3GXGA 4I8NA 2AZRA 4PVGA 2CM3A 3O4TA 5AWXA 2NLKA 2HB1A 2R0BA 5KA2A 4GE6A 3RO1A 2G6ZA 1GFYA 1T4JA 1I9SA 2H02A 1OEUA 3D42A 3EU0A 1YWFA 2OUDA 2B4SA 1OEMX 5KA7A 2I6JA 3QCIA 3ZMQA 1WCHA 3D9CA 1NZ7A 2E0TA 3O4SA 1C87A 1PXHA 1T49A 2FJNA 2Q05A 2BV5A 5IBMA 4YAAA 2HNPA 4KYQA 2OZ5A 4WTYA 2I4GA 1I9TA 1Q6TA 3EAXA 2J16B 4HJQA 4R30A 5K25A 1YN9A 2CMBA 2CMAA 4ERCA 2OOQA 3PS5A 2DXPA 2F6WA 1C84A 4ICZA 1NNYA 4NX8A 4HRFA 3AWEA 3QCJA 4RHGA 2H4KA 3AWGA 3I7ZA 2I6IA 3U96A 5GTJA 2Y2FA 2I75A 2VEVA 2CFVA 2Y96A 2C7SA 4D3QA 2I4HA 4GE5A 2HCMA 4QBEA 2BZLA 2CM2A 1Q6PA 1YGRA 4QBWA 2PA5A 3QCEA 3V0EA 1X24A 3S3HA 3ZM2A 1PTUA 3V0FA 1WRMA 4OHDA 4B04A 1WAXA 3QCFA 4IKCA 4GE2A 2C46A 1OHDA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1NWE A;  2HXP A;  1L8K A;  2WGP A;  5KA8 A;  3ZV2 A;  2HC1 A;  2I3R A;  3QCM A;  2BGE A;  4D3P A;  4JBC A;  5KA4 A;  1ONY A;  3F9B A;  2VEU A;  1G7F A;  4PYH A;  4DGP A;  1Q6M A;  4GS0 A;  1JLN A;  3QCN A;  1XRI A;  5EHR A;  5M43 A;  1YGU A;  1LAR A;  4RI4 A;  2QBS A;  1NO6 A;  1SUG A;  1OHE A;  3EB1 A;  4OHE A;  1FQ1 A;  3ZM1 A;  4GRZ A;  3S3K A;  1L8G A;  3QCD A;  5KAA A;  2PT0 A;  2QDM A;  3O5X A;  4NYH A;  3S3F A;  3OLR A;  2ZMM A;  4QUN A;  1OEV A;  1XXP A;  2AHS A;  3RZ2 A;  2BIJ A;  3EZZ A;  4TVV A;  2PBN A;  3M4U A;  1AAX A;  2PSZ A;  2VEW A;  1KAV A;  4JMJ A;  3BRH A;  1XBO A;  2I6O A;  5IBS A;  2F6V A;  2M3V A;  1KAK A;  4RDD A;  4WU2 A;  1BZH A;  3F99 A;  3V0G A;  5BUG A;  2QBQ A;  4GWF A;  2B4U A;  4AZ1 A;  1J4X A;  3F9A A;  3V0J A;  1T48 A;  1R6H A;  4BPC A;  1JF7 A;  3A5K A;  1ZZW A;  1RXD A;  1PA9 A;  3EMU A;  1YPT A;  4H1O A;  2FJM A;  3RGQ A;  3BLU A;  5KAD A;  1GWZ A;  1EEN A;  2F71 A;  3O3L A;  1G1H A;  1YFO A;  4J51 A;  3ZM0 A;  2PQ5 A;  2FH7 A;  2J17 A;  2H04 A;  3H2X A;  2I6M A;  1ECV A;  3GXH A;  4ZN5 A;  3QCK A;  2VEY A;  3CM3 A;  3SME A;  3CWE A;  1BZC A;  1PH0 A;  1U24 A;  2CMC A;  2P4D A;  3RGO A;  3I36 A;  4QUM A;  1XXV A;  5EHP A;  2YDU A;  2H4V A;  2G59 A;  2F46 A;  4KYR A;  1BZJ A;  1YTW A;  4NWG A;  1Q6J A;  4Y2E A;  4H34 A;  1VHR A;  2CNE A;  2F6Z A;  3QCC A;  4GFV A;  1EEO A;  3V0I A;  2GP0 A;  2QDC A;  1OES A;  4RI5 A;  3B7O A;  1D5R A;  2NV5 A;  1OET A;  1QZ0 A;  4WU3 A;  3ZMP A;  4D3R A;  3V0H A;  3D1O A;  1G4U S;  1PA1 A;  1U25 A;  5K9W A;  3QKQ A;  2ZN7 A;  2JJD A;  5BZX A;  4R0S A;  5HDE A;  2H03 A;  2NTA A;  2Q47 A;  3BM8 A;  1OHC A;  5K9V A;  1OEO X;  1G7G A;  3S3E A;  5KA0 A;  2I42 A;  2MBC A;  2QCT A;  2A8B A;  4OHL A;  3LJ8 A;  3O4U A;  2P6X A;  3D1H A;  2I6P A;  2CNH A;  5KAC A;  3S4O A;  1PTY A;  4JNB A;  1QXK A;  3OMH A;  4BJO A;  1M3G A;  1NL9 A;  1RPM A;  1P15 A;  1XM2 A;  4HJP A;  1G4W R;  2B3O A;  2HC2 A;  1LYV A;  1FPZ A;  4OHH A;  5KA1 A;  4WOH A;  1ZCL A;  4GFU A;  1LQF A;  1Q6N A;  4OHI A;  4YR8 B;  1YTN A;  1ZC0 A;  4RH5 A;  4QAP A;  2CNI A;  3MOW A;  3MOZ A;  3QCL A;  2NT2 A;  2NT7 A;  2A3K A;  3QCH A;  5I6V A;  2IMG A;  2CNF A;  1ONZ A;  2HNQ A;  2PI7 A;  4JMK A;  3BLT A;  5BZZ A;  2F6T A;  5KAB A;  2H4G A;  3AWF A;  4MBB A;  3I80 A;  2BGD A;  2GWO A;  2QBR A;  3MMJ A;  5LXQ B;  2B49 A;  3V0D A;  2QEP A;  2I3U A;  2CM7 A;  1C83 A;  2F6F A;  1A5Y A;  4NWF A;  1C85 A;  2OC3 A;  1NWL A;  4KI9 A;  5K24 A;  3QCG A;  2B4P A;  3A5J A;  2B07 A;  2I1Y A;  4GRY A;  2B4O A;  1Q6S A;  1FPR A;  4RKK A;  2HVL A;  2RF6 A;  1PTV A;  5J8R A;  5KA9 A;  2QCJ A;  2NZ6 A;  2GJT A;  1PTT A;  2F6Y A;  5BX1 A;  1Q1M A;  1V3A A;  1PYN A;  1MKP A;  1U26 A;  2CM8 A;  3D1Q A;  2QDP A;  3N0A A;  2QBP A;  4ZRT A;  2J16 A;  5K22 A;  2I5X A;  4R0T A;  4Z6B A;  1YTS A;  2VEX A;  5K23 A;  3SR9 A;  4QAH A;  4S0G A;  3QCB A;  3F41 A;  1C86 A;  1I57 A;  4ZI4 A;  5KA3 A;  1ZCK A;  5MMZ B;  3QKP A;  3S4E A;  1G1G A;  3F81 A;  4Y14 A;  2CJZ A;  4RH9 A;  1C88 A;  3ZM3 A;  1G1F A;  2HY3 A;  2SHP A;  2F70 A;  2I4E A;  4DGX A;  2ESB A;  3D44 A;  4NND A;  3NME A;  1YZ4 A;  2CNG A;  3GXG A;  4I8N A;  2AZR A;  4PVG A;  2CM3 A;  3O4T A;  5AWX A;  2NLK A;  2HB1 A;  2R0B A;  5KA2 A;  4GE6 A;  3RO1 A;  2G6Z A;  1GFY A;  1T4J A;  1I9S A;  2H02 A;  1OEU A;  3D42 A;  3EU0 A;  1YWF A;  2OUD A;  2B4S A;  1OEM X;  5KA7 A;  2I6J A;  3QCI A;  3ZMQ A;  1WCH A;  3D9C A;  1NZ7 A;  2E0T A;  3O4S A;  1C87 A;  1PXH A;  1T49 A;  2FJN A;  2Q05 A;  2BV5 A;  5IBM A;  4YAA A;  2HNP A;  4KYQ A;  2OZ5 A;  4WTY A;  2I4G A;  1I9T A;  1Q6T A;  3EAX A;  2J16 B;  4HJQ A;  4R30 A;  5K25 A;  1YN9 A;  2CMB A;  2CMA A;  4ERC A;  2OOQ A;  3PS5 A;  2DXP A;  2F6W A;  1C84 A;  4ICZ A;  1NNY A;  4NX8 A;  4HRF A;  3AWE A;  3QCJ A;  4RHG A;  2H4K A;  3AWG A;  3I7Z A;  2I6I A;  3U96 A;  5GTJ A;  2Y2F A;  2I75 A;  2VEV A;  2CFV A;  2Y96 A;  2C7S A;  4D3Q A;  2I4H A;  4GE5 A;  2HCM A;  4QBE A;  2BZL A;  2CM2 A;  1Q6P A;  1YGR A;  4QBW A;  2PA5 A;  3QCE A;  3V0E A;  1X24 A;  3S3H A;  3ZM2 A;  1PTU A;  3V0F A;  1WRM A;  4OHD A;  4B04 A;  1WAX A;  3QCF A;  4IKC A;  4GE2 A;  2C46 A;  1OHD A; 
#chains in the Genus database with same CATH topology
 1NWE A;  2HXP A;  1L8K A;  2WGP A;  5KA8 A;  3ZV2 A;  2HC1 A;  2I3R A;  2WJP A;  3QCM A;  2BGE A;  4D3P A;  4JBC A;  5KA4 A;  1ONY A;  3F9B A;  2VEU A;  1G7F A;  4PYH A;  4DGP A;  1Q6M A;  4GS0 A;  1JLN A;  2Y67 A;  3QCN A;  1W7K A;  1XRI A;  5EHR A;  5M43 A;  1YGU A;  1LAR A;  4RI4 A;  2QBS A;  1NO6 A;  5A5F A;  1SUG A;  1OHE A;  1JBW A;  3EB1 A;  4OHE A;  1FQ1 A;  3ZM1 A;  2VTE A;  4GRZ A;  3S3K A;  1L8G A;  3QCD A;  5KAA A;  2PT0 A;  2QDM A;  3O5X A;  4NYH A;  3S3F A;  2XJA A;  3OLR A;  2ZMM A;  4QUN A;  1GG4 A;  1OEV A;  1XXP A;  2AHS A;  3RZ2 A;  2BIJ A;  3EZZ A;  4TVV A;  2PBN A;  3M4U A;  1AAX A;  2PSZ A;  2VEW A;  1KAV A;  4JMJ A;  3BRH A;  3ZM6 A;  1XBO A;  2I6O A;  5IBS A;  2F6V A;  2M3V A;  1KAK A;  4RDD A;  4WU2 A;  1BZH A;  3F99 A;  3V0G A;  5BUG A;  2QBQ A;  4GWF A;  2B4U A;  3LK7 A;  4AZ1 A;  1J4X A;  3F9A A;  3V0J A;  1T48 A;  2WTZ A;  1R6H A;  4BPC A;  1JF7 A;  3A5K A;  1ZZW A;  1RXD A;  1PA9 A;  3EMU A;  1YPT A;  4H1O A;  2FJM A;  3RGQ A;  3BLU A;  5KAD A;  1GWZ A;  3HN7 A;  1EEN A;  2F71 A;  3O3L A;  1G1H A;  1YFO A;  4J51 A;  3ZM0 A;  2PQ5 A;  2FH7 A;  2J17 A;  3MVN A;  2H04 A;  3H2X A;  2I6M A;  1ECV A;  3GXH A;  4ZN5 A;  3QCK A;  2VEY A;  3CM3 A;  3SME A;  3CWE A;  1BZC A;  1PH0 A;  1U24 A;  2CMC A;  2P4D A;  3RGO A;  3I36 A;  4BUB A;  4QUM A;  1XXV A;  5EHP A;  2YDU A;  1GQQ A;  2H4V A;  2G59 A;  2F46 A;  4KYR A;  1BZJ A;  1YTW A;  4NWG A;  1Q6J A;  4Y2E A;  4H34 A;  2AM1 A;  1VHR A;  2CNE A;  2F6Z A;  3QCC A;  4GFV A;  1EEO A;  2JFF A;  3V0I A;  2GP0 A;  2QDC A;  1OES A;  4RI5 A;  3B7O A;  1D5R A;  2NV5 A;  2JFG A;  1OET A;  1QZ0 A;  4WU3 A;  3ZMP A;  4D3R A;  3V0H A;  3D1O A;  1G4U S;  1PA1 A;  1U25 A;  5K9W A;  3QKQ A;  2ZN7 A;  2JJD A;  5BZX A;  4R0S A;  5HDE A;  2H03 A;  2NTA A;  2Q47 A;  3BM8 A;  1OHC A;  5K9V A;  1OEO X;  1G7G A;  3S3E A;  5KA0 A;  2I42 A;  2MBC A;  2QCT A;  2A8B A;  2UUP A;  4OHL A;  3ZM5 A;  3LJ8 A;  3O4U A;  2P6X A;  3D1H A;  2I6P A;  2CNH A;  5KAC A;  3S4O A;  1PTY A;  4JNB A;  1QXK A;  3OMH A;  4BJO A;  1M3G A;  1NL9 A;  1RPM A;  2GC5 A;  1P15 A;  1XM2 A;  4HJP A;  1G4W R;  2B3O A;  2AM2 A;  2HC2 A;  1LYV A;  1FPZ A;  4OHH A;  5KA1 A;  4WOH A;  1ZCL A;  4GFU A;  1LQF A;  1Q6N A;  4OHI A;  4YR8 B;  1YTN A;  1ZC0 A;  4RH5 A;  4QAP A;  2CNI A;  3MOW A;  3MOZ A;  2NT2 A;  2NT7 A;  2A3K A;  3QCL A;  3QCH A;  1UAG A;  2IMG A;  5I6V A;  2CNF A;  1ONZ A;  2HNQ A;  2PI7 A;  4JMK A;  3BLT A;  5BZZ A;  2F6T A;  5KAB A;  2H4G A;  3AWF A;  4MBB A;  3I80 A;  2BGD A;  2GWO A;  2QBR A;  3MMJ A;  5LXQ B;  2B49 A;  3V0D A;  4CVL A;  2JFH A;  2QEP A;  2I3U A;  2CM7 A;  1C83 A;  2F6F A;  1A5Y A;  4NWF A;  1C85 A;  2OC3 A;  1NWL A;  4KI9 A;  5K24 A;  3QCG A;  2B4P A;  3A5J A;  2B07 A;  2I1Y A;  4GRY A;  2B4O A;  1Q6S A;  1FPR A;  2VOR A;  4RKK A;  2HVL A;  2RF6 A;  1PTV A;  5J8R A;  5KA9 A;  2QCJ A;  4BUC A;  2NZ6 A;  2Y66 A;  2GJT A;  1PTT A;  2F6Y A;  5BX1 A;  1JBV A;  1Q1M A;  2UAG A;  1V3A A;  1PYN A;  1MKP A;  1U26 A;  2CM8 A;  2VOS A;  3D1Q A;  2QDP A;  3N0A A;  2QBP A;  4CVK A;  4ZRT A;  2J16 A;  5K22 A;  2I5X A;  4R0T A;  4Z6B A;  1YTS A;  3NRS A;  2VEX A;  4C13 A;  3UAG A;  5K23 A;  4UAG A;  3SR9 A;  4QAH A;  4S0G A;  3QCB A;  3F41 A;  1C86 A;  1GQY A;  1EEH A;  1I57 A;  4ZI4 A;  4CVM A;  5KA3 A;  1ZCK A;  5MMZ B;  3QKP A;  1P31 A;  3S4E A;  1G1G A;  3F81 A;  4Y14 A;  2GCB A;  2CJZ A;  4RH9 A;  1C88 A;  1O5Z A;  3ZM3 A;  1G1F A;  2HY3 A;  1FGS A;  2SHP A;  2F70 A;  2I4E A;  4DGX A;  2ESB A;  3D44 A;  4NND A;  3NME A;  1YZ4 A;  2CNG A;  3GXG A;  4I8N A;  2AZR A;  4C12 A;  4PVG A;  2CM3 A;  3O4T A;  5AWX A;  2NLK A;  2HB1 A;  2R0B A;  5KA2 A;  4GE6 A;  3RO1 A;  2G6Z A;  1GFY A;  1T4J A;  1I9S A;  2H02 A;  1OEU A;  2GCA A;  1P3D A;  1W78 A;  3D42 A;  3EU0 A;  1YWF A;  2OUD A;  2B4S A;  1OEM X;  5KA7 A;  1E0D A;  2I6J A;  3QCI A;  3ZMQ A;  1WCH A;  2Y68 A;  3D9C A;  1NZ7 A;  2E0T A;  3O4S A;  1C87 A;  1PXH A;  1T49 A;  2FJN A;  2Q05 A;  2BV5 A;  5IBM A;  3PYZ A;  4YAA A;  2HNP A;  4KYQ A;  2OZ5 A;  4WTY A;  2I4G A;  1I9T A;  1Q6T A;  3EAX A;  2J16 B;  4HJQ A;  4R30 A;  2Y1O A;  5K25 A;  1YN9 A;  2CMB A;  2CMA A;  4ERC A;  2OOQ A;  3PS5 A;  2DXP A;  3N2A A;  2F6W A;  1C84 A;  4ICZ A;  1NNY A;  4NX8 A;  4HRF A;  3AWE A;  3QCJ A;  4RHG A;  1J6U A;  2H4K A;  1E8C A;  3AWG A;  3QCZ A;  3I7Z A;  2I6I A;  3U96 A;  4QF5 A;  5GTJ A;  2Y2F A;  2I75 A;  2VTD A;  2VEV A;  4ZIY A;  2CFV A;  2Y96 A;  2XPC A;  2C7S A;  4D3Q A;  2I4H A;  4GE5 A;  2HCM A;  5A5E A;  4QBE A;  2BZL A;  2CM2 A;  1Q6P A;  2X5O A;  1YGR A;  4QBW A;  4QDI A;  2PA5 A;  3QCE A;  3V0E A;  1X24 A;  2UUO A;  4HV4 A;  2GC6 A;  3S3H A;  3ZM2 A;  3ZL8 A;  1PTU A;  3V0F A;  1WRM A;  4OHD A;  4B04 A;  1WAX A;  3QCF A;  4IKC A;  4GE2 A;  2C46 A;  2F00 A;  1OHD A; 
#chains in the Genus database with same CATH homology
 1NWE A;  2HXP A;  1L8K A;  2WGP A;  5KA8 A;  3ZV2 A;  2HC1 A;  2I3R A;  3QCM A;  2BGE A;  4D3P A;  4JBC A;  5KA4 A;  1ONY A;  3F9B A;  2VEU A;  1G7F A;  4PYH A;  4DGP A;  1Q6M A;  4GS0 A;  1JLN A;  3QCN A;  1XRI A;  5EHR A;  5M43 A;  1YGU A;  1LAR A;  4RI4 A;  2QBS A;  1NO6 A;  1SUG A;  1OHE A;  3EB1 A;  4OHE A;  1FQ1 A;  3ZM1 A;  4GRZ A;  3S3K A;  1L8G A;  3QCD A;  5KAA A;  2PT0 A;  2QDM A;  3O5X A;  4NYH A;  3S3F A;  3OLR A;  2ZMM A;  4QUN A;  1OEV A;  1XXP A;  2AHS A;  3RZ2 A;  2BIJ A;  3EZZ A;  4TVV A;  2PBN A;  3M4U A;  1AAX A;  2PSZ A;  2VEW A;  1KAV A;  4JMJ A;  3BRH A;  1XBO A;  2I6O A;  5IBS A;  2F6V A;  2M3V A;  1KAK A;  4RDD A;  4WU2 A;  1BZH A;  3F99 A;  3V0G A;  5BUG A;  2QBQ A;  4GWF A;  2B4U A;  4AZ1 A;  1J4X A;  3F9A A;  3V0J A;  1T48 A;  1R6H A;  4BPC A;  1JF7 A;  3A5K A;  1ZZW A;  1RXD A;  1PA9 A;  3EMU A;  1YPT A;  4H1O A;  2FJM A;  3RGQ A;  3BLU A;  5KAD A;  1GWZ A;  1EEN A;  2F71 A;  3O3L A;  1G1H A;  1YFO A;  4J51 A;  3ZM0 A;  2PQ5 A;  2FH7 A;  2J17 A;  2H04 A;  3H2X A;  2I6M A;  1ECV A;  3GXH A;  4ZN5 A;  3QCK A;  2VEY A;  3CM3 A;  3SME A;  3CWE A;  1BZC A;  1PH0 A;  1U24 A;  2CMC A;  2P4D A;  3RGO A;  3I36 A;  4QUM A;  1XXV A;  5EHP A;  2YDU A;  2H4V A;  2G59 A;  2F46 A;  4KYR A;  1BZJ A;  1YTW A;  4NWG A;  1Q6J A;  4Y2E A;  4H34 A;  1VHR A;  2CNE A;  2F6Z A;  3QCC A;  4GFV A;  1EEO A;  3V0I A;  2GP0 A;  2QDC A;  1OES A;  4RI5 A;  3B7O A;  1D5R A;  2NV5 A;  1OET A;  1QZ0 A;  4WU3 A;  3ZMP A;  4D3R A;  3V0H A;  3D1O A;  1G4U S;  1PA1 A;  1U25 A;  5K9W A;  3QKQ A;  2ZN7 A;  2JJD A;  5BZX A;  4R0S A;  5HDE A;  2H03 A;  2NTA A;  2Q47 A;  3BM8 A;  1OHC A;  5K9V A;  1OEO X;  1G7G A;  3S3E A;  5KA0 A;  2I42 A;  2MBC A;  2QCT A;  2A8B A;  4OHL A;  3LJ8 A;  3O4U A;  2P6X A;  3D1H A;  2I6P A;  2CNH A;  5KAC A;  3S4O A;  1PTY A;  4JNB A;  1QXK A;  3OMH A;  4BJO A;  1M3G A;  1NL9 A;  1RPM A;  1P15 A;  1XM2 A;  4HJP A;  1G4W R;  2B3O A;  2HC2 A;  1LYV A;  1FPZ A;  4OHH A;  5KA1 A;  4WOH A;  1ZCL A;  4GFU A;  1LQF A;  1Q6N A;  4OHI A;  4YR8 B;  1YTN A;  1ZC0 A;  4RH5 A;  4QAP A;  2CNI A;  3MOW A;  3MOZ A;  3QCL A;  2NT2 A;  2NT7 A;  2A3K A;  3QCH A;  5I6V A;  2IMG A;  2CNF A;  1ONZ A;  2HNQ A;  2PI7 A;  4JMK A;  3BLT A;  5BZZ A;  2F6T A;  5KAB A;  2H4G A;  3AWF A;  4MBB A;  3I80 A;  2BGD A;  2GWO A;  2QBR A;  3MMJ A;  5LXQ B;  2B49 A;  3V0D A;  2QEP A;  2I3U A;  2CM7 A;  1C83 A;  2F6F A;  1A5Y A;  4NWF A;  1C85 A;  2OC3 A;  1NWL A;  4KI9 A;  5K24 A;  3QCG A;  2B4P A;  3A5J A;  2B07 A;  2I1Y A;  4GRY A;  2B4O A;  1Q6S A;  1FPR A;  4RKK A;  2HVL A;  2RF6 A;  1PTV A;  5J8R A;  5KA9 A;  2QCJ A;  2NZ6 A;  2GJT A;  1PTT A;  2F6Y A;  5BX1 A;  1Q1M A;  1V3A A;  1PYN A;  1MKP A;  1U26 A;  2CM8 A;  3D1Q A;  2QDP A;  3N0A A;  2QBP A;  4ZRT A;  2J16 A;  5K22 A;  2I5X A;  4R0T A;  4Z6B A;  1YTS A;  2VEX A;  5K23 A;  3SR9 A;  4QAH A;  4S0G A;  3QCB A;  3F41 A;  1C86 A;  1I57 A;  4ZI4 A;  5KA3 A;  1ZCK A;  5MMZ B;  3QKP A;  3S4E A;  1G1G A;  3F81 A;  4Y14 A;  2CJZ A;  4RH9 A;  1C88 A;  3ZM3 A;  1G1F A;  2HY3 A;  2SHP A;  2F70 A;  2I4E A;  4DGX A;  2ESB A;  3D44 A;  4NND A;  3NME A;  1YZ4 A;  2CNG A;  3GXG A;  4I8N A;  2AZR A;  4PVG A;  2CM3 A;  3O4T A;  5AWX A;  2NLK A;  2HB1 A;  2R0B A;  5KA2 A;  4GE6 A;  3RO1 A;  2G6Z A;  1GFY A;  1T4J A;  1I9S A;  2H02 A;  1OEU A;  3D42 A;  3EU0 A;  1YWF A;  2OUD A;  2B4S A;  1OEM X;  5KA7 A;  2I6J A;  3QCI A;  3ZMQ A;  1WCH A;  3D9C A;  1NZ7 A;  2E0T A;  3O4S A;  1C87 A;  1PXH A;  1T49 A;  2FJN A;  2Q05 A;  2BV5 A;  5IBM A;  4YAA A;  2HNP A;  4KYQ A;  2OZ5 A;  4WTY A;  2I4G A;  1I9T A;  1Q6T A;  3EAX A;  2J16 B;  4HJQ A;  4R30 A;  5K25 A;  1YN9 A;  2CMB A;  2CMA A;  4ERC A;  2OOQ A;  3PS5 A;  2DXP A;  2F6W A;  1C84 A;  4ICZ A;  1NNY A;  4NX8 A;  4HRF A;  3AWE A;  3QCJ A;  4RHG A;  2H4K A;  3AWG A;  3I7Z A;  2I6I A;  3U96 A;  5GTJ A;  2Y2F A;  2I75 A;  2VEV A;  2CFV A;  2Y96 A;  2C7S A;  4D3Q A;  2I4H A;  4GE5 A;  2HCM A;  4QBE A;  2BZL A;  2CM2 A;  1Q6P A;  1YGR A;  4QBW A;  2PA5 A;  3QCE A;  3V0E A;  1X24 A;  3S3H A;  3ZM2 A;  1PTU A;  3V0F A;  1WRM A;  4OHD A;  4B04 A;  1WAX A;  3QCF A;  4IKC A;  4GE2 A;  2C46 A;  1OHD A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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