1G1FA

Crystal structure of protein tyrosine phosphatase 1b complexed with a tri-phosphorylated peptide (rdi(ptr)etd(ptr)(ptr)rk) from the insulin receptor kinase
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHASAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase, signaling protein
source organism Homo sapiens
molecule keywords PROTEIN TYROSINE PHOSPHATASE 1B
total genus 98
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1g1fA00
3EAXA 1L8KA 2H04A 3V0FA 2CM8A 1J4XA 2BIJA 1G7FA 1YN9A 2ZN7A 3V0DA 2CM7A 3QCEA 1U24A 2VEXA 5KACA 2H03A 2MBCA 1FQ1A 3EB1A 4YR8B 3A5KA 1XRIA 2OUDA 1OETA 3ZM0A 2VEWA 2RF6A 3OLRA 2VEVA 2VEUA 5AWXA 1WAXA 3QCGA 4GFUA 3AWFA 2QDPA 4JMJA 2BGDA 4ZRTA 3D1HA 2GWOA 1PH0A 1PTTA 5KA7A 1C83A 1Q1MA 4NWGA 1PXHA 3N0AA 3SR9A 4R30A 5KAAA 3AWGA 3ZMQA 3EZZA 2NLKA 4GE6A 2HB1A 4GE5A 2B4UA 3S3KA 1ONZA 5BX1A 4Z6BA 2HXPA 2FJNA 2QBQA 2QDCA 4B04A 1OHEA 2DXPA 2F6FA 4ZI4A 2OOQA 2F46A 1PTYA 3QCKA 1T4JA 1RXDA 1YZ4A 2I6JA 4OHDA 1U26A 3S4OA 1LYVA 1ECVA 4JMKA 2IMGA 4RDDA 3NMEA 1C87A 2CNGA 2G6ZA 2PQ5A 1R6HA 2QDMA 2NTAA 4BJOA 5IBMA 5KA1A 2ZMMA 3ZMPA 5K22A 3SMEA 4WU3A 2B07A 3EU0A 1YGUA 3MOWA 4D3RA 4QAPA 2P4DA 4KYQA 1NNYA 3BRHA 3V0JA 5KABA 2I6IA 1ZC0A 2F71A 4QAHA 4RHGA 3OMHA 3V0EA 3ZM2A 1Q6NA 1C85A 2CM2A 3QCCA 2VEYA 1FPRA 3QCHA 2NZ6A 5EHPA 3B7OA 5K9VA 4RH5A 3M4UA 4RH9A 1NZ7A 2G59A 4QBWA 3O4TA 3MMJA 2GJTA 2HC2A 2BV5A 1YPTA 1OHDA 1LQFA 4ZN5A 2H4GA 2HNQA 2QBRA 5K25A 3D42A 4WU2A 1EEOA 2F70A 4OHHA 2CJZA 2I3RA 2QCTA 1SUGA 1OHCA 2F6VA 2J17A 5KA8A 5K24A 1M3GA 3QKPA 1KAVA 3MOZA 4HJQA 3GXGA 4RI4A 1D5RA 5BZXA 3QCBA 2Q05A 4D3PA 1PA1A 5MMZB 2I6PA 1ZCKA 1C84A 1YGRA 3RZ2A 1XXVA 3V0IA 3O4UA 5BUGA 2I4HA 5K9WA 4ICZA 3GXHA 5KADA 1G1HA 2CMBA 1T49A 4HJPA 2B49A 2QCJA 3QCJA 1BZHA 3U96A 3RO1A 2BZLA 1PYNA 1Q6SA 2HY3A 3CWEA 1T48A 4GRZA 5KA0A 1OEUA 4ERCA 2BGEA 1WRMA 1JLNA 2CNFA 4AZ1A 4Y14A 1G1GA 4JBCA 1FPZA 1V3AA 2C7SA 3BLTA 1NWLA 2Y2FA 2B3OA 1I57A 2SHPA 2I75A 5BZZA 1OESA 4Y2EA 4S0GA 1PTVA 4JNBA 1ONYA 1LARA 1QZ0A 4KYRA 4YAAA 2P6XA 2HVLA 3D9CA 5J8RA 3F81A 4GS0A 5KA4A 1VHRA 2ESBA 4HRFA 2NT2A 2F6WA 2CNIA 2F6ZA 3LJ8A 2CNHA 3A5JA 1L8GA 3QCIA 2I4GA 3S4EA 2F6TA 4GWFA 4WOHA 1NO6A 4RKKA 1P15A 1A5YA 3D1QA 2PSZA 1C86A 2I1YA 4GFVA 4QUMA 1GFYA 5KA3A 5M43A 3V0GA 1NL9A 3F9AA 1PTUA 4QBEA 2B4SA 1YTNA 2J16B 4D3QA 2I3UA 4RI5A 2HCMA 2H02A 4IKCA 3QCMA 5GTJA 3ZM1A 1YTSA 3PS5A 1Q6MA 4KI9A 1AAXA 3QKQA 2CMAA 5I6VA 3D44A 3I36A 2PBNA 2HNPA 3F41A 1I9SA 4TVVA 4WTYA 4H1OA 2B4PA 2FH7A 4OHEA 1C88A 5KA9A 1YTWA 5HDEA 2PT0A 3H2XA 1XM2A 1OEMX 1G1FA 1MKPA 1EENA 3O4SA 2B4OA 1OEVA 4R0TA 1JF7A 2F6YA 2I42A 3BM8A 3F99A 4J51A 4R0SA 1G4US 4NNDA 1OEOX 4QUNA 4H34A 1YFOA 4I8NA 2J16A 1KAKA 4GE2A 1XXPA 2H4KA 2QBSA 2E0TA 4OHLA 4NX8A 1QXKA 2A8BA 2R0BA 2AHSA 3S3HA 2QBPA 1I9TA 1XBOA 2A3KA 2Q47A 2Y96A 4NYHA 5K23A 2I6MA 3S3FA 1ZZWA 3BLUA 1BZJA 3QCFA 4PYHA 3ZM3A 3AWEA 2I4EA 3I7ZA 2OZ5A 1Q6TA 3S3EA 2I5XA 1X24A 1Q6JA 4GRYA 4NWFA 1BZCA 2PA5A 4MBBA 3V0HA 1Q6PA 1YWFA 3F9BA 5IBSA 3QCLA 2HC1A 2CMCA 1GWZA 2OC3A 2JJDA 4DGXA 1NWEA 2I6OA 2WGPA 3EMUA 3CM3A 1PA9A 1ZCLA 3QCNA 3O5XA 4OHIA 2C46A 2CM3A 3O3LA 3QCDA 1RPMA 1G4WR 2FJMA 3RGQA 2M3VA 2PI7A 5LXQB 1G7GA 2YDUA 5KA2A 5EHRA 2GP0A 3D1OA 4BPCA 4DGPA 3ZV2A 4PVGA 2QEPA 3I80A 1WCHA 2NV5A 2AZRA 2CFVA 1U25A 2NT7A 2CNEA 3RGOA 2H4VA
chains in the Genus database with same CATH superfamily
3EAXA 2UUOA 1L8KA 2H04A 3V0FA 2CM8A 1J4XA 2BIJA 1G7FA 1YN9A 2F00A 2ZN7A 3V0DA 2CM7A 1U24A 3QCEA 2VEXA 5KACA 2H03A 2MBCA 1FQ1A 3EB1A 4YR8B 3A5KA 1XRIA 2OUDA 1OETA 3ZM0A 4BUCA 2VEWA 2RF6A 3OLRA 2VEVA 2VEUA 5AWXA 1WAXA 3QCGA 4GFUA 3AWFA 2QDPA 4JMJA 2BGDA 4ZRTA 3D1HA 2GWOA 1PH0A 1PTTA 5KA7A 1C83A 1Q1MA 4NWGA 1PXHA 3N0AA 3SR9A 4R30A 5KAAA 3AWGA 3ZMQA 3EZZA 2NLKA 4GE6A 2HB1A 4GE5A 2B4UA 3S3KA 1ONZA 5BX1A 4Z6BA 2HXPA 2FJNA 2QBQA 2QDCA 4CVMA 4B04A 4CVKA 1OHEA 2DXPA 1GQQA 2F6FA 4ZI4A 2OOQA 2GC6A 2F46A 1PTYA 3QCKA 1T4JA 1RXDA 3QCZA 1YZ4A 2AM2A 2I6JA 2UUPA 5A5FA 4OHDA 1U26A 3S4OA 1LYVA 1ECVA 4JMKA 2IMGA 4RDDA 3NMEA 4C12A 1C87A 2CNGA 2GCAA 2G6ZA 2PQ5A 1R6HA 2QDMA 2NTAA 4BJOA 5IBMA 5KA1A 2ZMMA 3ZMPA 5K22A 3SMEA 2WJPA 4WU3A 2B07A 4BUBA 4ZIYA 3EU0A 1YGUA 3MOWA 4D3RA 4QAPA 1JBWA 2P4DA 4KYQA 1NNYA 3BRHA 3V0JA 5KABA 2I6IA 1ZC0A 2F71A 4QAHA 2VTEA 4RHGA 3OMHA 4C13A 3V0EA 3ZM2A 3HN7A 5A5EA 1Q6NA 1C85A 2CM2A 3QCCA 2VEYA 1FPRA 3QCHA 2NZ6A 5EHPA 3B7OA 5K9VA 4RH5A 3M4UA 4RH9A 1NZ7A 2G59A 4QBWA 3O4TA 3MMJA 2GJTA 2HC2A 1UAGA 1JBVA 2BV5A 1E8CA 1YPTA 1OHDA 1LQFA 4ZN5A 2H4GA 2HNQA 2QBRA 5K25A 3D42A 4WU2A 2XPCA 1EEOA 2F70A 4OHHA 2CJZA 2I3RA 2QCTA 1SUGA 1OHCA 2F6VA 2J17A 1GQYA 3MVNA 5KA8A 5K24A 1M3GA 3QKPA 1W78A 1KAVA 3MOZA 4HJQA 3GXGA 4RI4A 1D5RA 5BZXA 3QCBA 2Q05A 4QDIA 1PA1A 4D3PA 5MMZB 2I6PA 1ZCKA 1C84A 1YGRA 3RZ2A 2Y66A 1XXVA 3V0IA 3O4UA 5BUGA 2I4HA 5K9WA 4ICZA 3GXHA 5KADA 1G1HA 2CMBA 1T49A 4HJPA 2B49A 2QCJA 3QCJA 1BZHA 2X5OA 3U96A 3RO1A 2BZLA 1PYNA 1Q6SA 2HY3A 3CWEA 2JFHA 1T48A 4GRZA 5KA0A 1OEUA 4ERCA 2BGEA 1WRMA 1JLNA 2CNFA 3NRSA 4AZ1A 4Y14A 1G1GA 4JBCA 1FPZA 3LK7A 1V3AA 2C7SA 3BLTA 1NWLA 2Y2FA 2B3OA 1I57A 2SHPA 2I75A 5BZZA 1OESA 2VOSA 4Y2EA 4S0GA 1PTVA 4JNBA 1ONYA 1LARA 1QZ0A 4KYRA 1J6UA 4YAAA 2UAGA 2P6XA 2HVLA 3D9CA 5J8RA 1P31A 3F81A 4GS0A 5KA4A 1VHRA 2ESBA 4HRFA 2NT2A 2F6WA 2CNIA 2F6ZA 3LJ8A 2CNHA 3A5JA 1L8GA 3QCIA 2I4GA 3S4EA 2F6TA 4GWFA 4WOHA 3PYZA 1NO6A 4RKKA 1P15A 1A5YA 3D1QA 2PSZA 1C86A 1O5ZA 2I1YA 4GFVA 4QUMA 1GFYA 5KA3A 5M43A 3V0GA 1NL9A 3F9AA 1PTUA 4QBEA 2B4SA 1YTNA 2J16B 4D3QA 3ZM6A 2I3UA 4RI5A 2HCMA 2H02A 4IKCA 3QCMA 2Y68A 5GTJA 3ZL8A 3ZM1A 1YTSA 3PS5A 1Q6MA 4KI9A 1AAXA 3QKQA 2CMAA 5I6VA 3D44A 1W7KA 2VTDA 3I36A 2PBNA 2HNPA 3F41A 1I9SA 4TVVA 4WTYA 4H1OA 2B4PA 2FH7A 2AM1A 1C88A 4OHEA 1P3DA 5KA9A 1YTWA 3UAGA 1GG4A 5HDEA 2PT0A 3H2XA 1XM2A 1FGSA 1EEHA 1OEMX 1G1FA 1MKPA 1EENA 3O4SA 2B4OA 1OEVA 4R0TA 1JF7A 2F6YA 2I42A 3BM8A 3F99A 4J51A 4R0SA 1G4US 4NNDA 1OEOX 4QUNA 4H34A 1YFOA 4I8NA 2J16A 1KAKA 2Y1OA 4GE2A 1XXPA 2H4KA 2QBSA 2E0TA 4OHLA 4NX8A 1QXKA 2A8BA 2R0BA 2AHSA 3S3HA 2QBPA 2JFGA 1I9TA 1XBOA 2A3KA 2Q47A 2VORA 3ZM5A 1E0DA 2Y96A 4NYHA 5K23A 2I6MA 3S3FA 1ZZWA 3BLUA 2GCBA 1BZJA 3QCFA 4PYHA 3ZM3A 3AWEA 2I4EA 3I7ZA 2OZ5A 1Q6TA 3S3EA 2I5XA 1X24A 1Q6JA 4GRYA 4CVLA 4NWFA 1BZCA 2PA5A 2XJAA 4MBBA 2Y67A 2JFFA 3V0HA 1Q6PA 1YWFA 3F9BA 5IBSA 3QCLA 2HC1A 2CMCA 1GWZA 2OC3A 2JJDA 4DGXA 1NWEA 2I6OA 2WGPA 3EMUA 3CM3A 1PA9A 1ZCLA 3QCNA 2WTZA 3O5XA 2GC5A 4OHIA 2C46A 2CM3A 3O3LA 3QCDA 4QF5A 1RPMA 1G4WR 2FJMA 3RGQA 2M3VA 2PI7A 5LXQB 1G7GA 2YDUA 5KA2A 5EHRA 2GP0A 3D1OA 4BPCA 4DGPA 4HV4A 3ZV2A 4PVGA 2QEPA 3I80A 1WCHA 2NV5A 2AZRA 3N2AA 2CFVA 1U25A 2NT7A 4UAGA 2CNEA 3RGOA 2H4VA
chains in the Genus database with same CATH topology
3EAXA 1L8KA 2H04A 3V0FA 2CM8A 1J4XA 2BIJA 1G7FA 1YN9A 2ZN7A 3V0DA 2CM7A 3QCEA 1U24A 2VEXA 5KACA 2H03A 2MBCA 1FQ1A 3EB1A 4YR8B 3A5KA 1XRIA 2OUDA 1OETA 3ZM0A 2VEWA 2RF6A 3OLRA 2VEVA 2VEUA 5AWXA 1WAXA 3QCGA 4GFUA 3AWFA 2QDPA 4JMJA 2BGDA 4ZRTA 3D1HA 2GWOA 1PH0A 1PTTA 5KA7A 1C83A 1Q1MA 4NWGA 1PXHA 3N0AA 3SR9A 4R30A 5KAAA 3AWGA 3ZMQA 3EZZA 2NLKA 4GE6A 2HB1A 4GE5A 2B4UA 3S3KA 1ONZA 5BX1A 4Z6BA 2HXPA 2FJNA 2QBQA 2QDCA 4B04A 1OHEA 2DXPA 2F6FA 4ZI4A 2OOQA 2F46A 1PTYA 3QCKA 1T4JA 1RXDA 1YZ4A 2I6JA 4OHDA 1U26A 3S4OA 1LYVA 1ECVA 4JMKA 2IMGA 4RDDA 3NMEA 1C87A 2CNGA 2G6ZA 2PQ5A 1R6HA 2QDMA 2NTAA 4BJOA 5IBMA 5KA1A 2ZMMA 3ZMPA 5K22A 3SMEA 4WU3A 2B07A 3EU0A 1YGUA 3MOWA 4D3RA 4QAPA 2P4DA 4KYQA 1NNYA 3BRHA 3V0JA 5KABA 2I6IA 1ZC0A 2F71A 4QAHA 4RHGA 3OMHA 3V0EA 3ZM2A 1Q6NA 1C85A 2CM2A 3QCCA 2VEYA 1FPRA 3QCHA 2NZ6A 5EHPA 3B7OA 5K9VA 4RH5A 3M4UA 4RH9A 1NZ7A 2G59A 4QBWA 3O4TA 3MMJA 2GJTA 2HC2A 2BV5A 1YPTA 1OHDA 1LQFA 4ZN5A 2H4GA 2HNQA 2QBRA 5K25A 3D42A 4WU2A 1EEOA 2F70A 4OHHA 2CJZA 2I3RA 2QCTA 1SUGA 1OHCA 2F6VA 2J17A 5KA8A 5K24A 1M3GA 3QKPA 1KAVA 3MOZA 4HJQA 3GXGA 4RI4A 1D5RA 5BZXA 3QCBA 2Q05A 4D3PA 1PA1A 5MMZB 2I6PA 1ZCKA 1C84A 1YGRA 3RZ2A 1XXVA 3V0IA 3O4UA 5BUGA 2I4HA 5K9WA 4ICZA 3GXHA 5KADA 1G1HA 2CMBA 1T49A 4HJPA 2B49A 2QCJA 3QCJA 1BZHA 3U96A 3RO1A 2BZLA 1PYNA 1Q6SA 2HY3A 3CWEA 1T48A 4GRZA 5KA0A 1OEUA 4ERCA 2BGEA 1WRMA 1JLNA 2CNFA 4AZ1A 4Y14A 1G1GA 4JBCA 1FPZA 1V3AA 2C7SA 3BLTA 1NWLA 2Y2FA 2B3OA 1I57A 2SHPA 2I75A 5BZZA 1OESA 4Y2EA 4S0GA 1PTVA 4JNBA 1ONYA 1LARA 1QZ0A 4KYRA 4YAAA 2P6XA 2HVLA 3D9CA 5J8RA 3F81A 4GS0A 5KA4A 1VHRA 2ESBA 4HRFA 2NT2A 2F6WA 2CNIA 2F6ZA 3LJ8A 2CNHA 3A5JA 1L8GA 3QCIA 2I4GA 3S4EA 2F6TA 4GWFA 4WOHA 1NO6A 4RKKA 1P15A 1A5YA 3D1QA 2PSZA 1C86A 2I1YA 4GFVA 4QUMA 1GFYA 5KA3A 5M43A 3V0GA 1NL9A 3F9AA 1PTUA 4QBEA 2B4SA 1YTNA 2J16B 4D3QA 2I3UA 4RI5A 2HCMA 2H02A 4IKCA 3QCMA 5GTJA 3ZM1A 1YTSA 3PS5A 1Q6MA 4KI9A 1AAXA 3QKQA 2CMAA 5I6VA 3D44A 3I36A 2PBNA 2HNPA 3F41A 1I9SA 4TVVA 4WTYA 4H1OA 2B4PA 2FH7A 4OHEA 1C88A 5KA9A 1YTWA 5HDEA 2PT0A 3H2XA 1XM2A 1OEMX 1G1FA 1MKPA 1EENA 3O4SA 2B4OA 1OEVA 4R0TA 1JF7A 2F6YA 2I42A 3BM8A 3F99A 4J51A 4R0SA 1G4US 4NNDA 1OEOX 4QUNA 4H34A 1YFOA 4I8NA 2J16A 1KAKA 4GE2A 1XXPA 2H4KA 2QBSA 2E0TA 4OHLA 4NX8A 1QXKA 2A8BA 2R0BA 2AHSA 3S3HA 2QBPA 1I9TA 1XBOA 2A3KA 2Q47A 2Y96A 4NYHA 5K23A 2I6MA 3S3FA 1ZZWA 3BLUA 1BZJA 3QCFA 4PYHA 3ZM3A 3AWEA 2I4EA 3I7ZA 2OZ5A 1Q6TA 3S3EA 2I5XA 1X24A 1Q6JA 4GRYA 4NWFA 1BZCA 2PA5A 4MBBA 3V0HA 1Q6PA 1YWFA 3F9BA 5IBSA 3QCLA 2HC1A 2CMCA 1GWZA 2OC3A 2JJDA 4DGXA 1NWEA 2I6OA 2WGPA 3EMUA 3CM3A 1PA9A 1ZCLA 3QCNA 3O5XA 4OHIA 2C46A 2CM3A 3O3LA 3QCDA 1RPMA 1G4WR 2FJMA 3RGQA 2M3VA 2PI7A 5LXQB 1G7GA 2YDUA 5KA2A 5EHRA 2GP0A 3D1OA 4BPCA 4DGPA 3ZV2A 4PVGA 2QEPA 3I80A 1WCHA 2NV5A 2AZRA 2CFVA 1U25A 2NT7A 2CNEA 3RGOA 2H4VA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3EAX A;  1L8K A;  2H04 A;  3V0F A;  2CM8 A;  1J4X A;  2BIJ A;  1G7F A;  1YN9 A;  2ZN7 A;  3V0D A;  2CM7 A;  3QCE A;  1U24 A;  2VEX A;  5KAC A;  2H03 A;  2MBC A;  1FQ1 A;  3EB1 A;  4YR8 B;  3A5K A;  1XRI A;  2OUD A;  1OET A;  3ZM0 A;  2VEW A;  2RF6 A;  3OLR A;  2VEV A;  2VEU A;  5AWX A;  1WAX A;  3QCG A;  4GFU A;  3AWF A;  2QDP A;  4JMJ A;  2BGD A;  4ZRT A;  3D1H A;  2GWO A;  1PH0 A;  1PTT A;  5KA7 A;  1C83 A;  1Q1M A;  4NWG A;  1PXH A;  3N0A A;  3SR9 A;  4R30 A;  5KAA A;  3AWG A;  3ZMQ A;  3EZZ A;  2NLK A;  4GE6 A;  2HB1 A;  4GE5 A;  2B4U A;  3S3K A;  1ONZ A;  5BX1 A;  4Z6B A;  2HXP A;  2FJN A;  2QBQ A;  2QDC A;  4B04 A;  1OHE A;  2DXP A;  2F6F A;  4ZI4 A;  2OOQ A;  2F46 A;  1PTY A;  3QCK A;  1T4J A;  1RXD A;  1YZ4 A;  2I6J A;  4OHD A;  1U26 A;  3S4O A;  1LYV A;  1ECV A;  4JMK A;  2IMG A;  4RDD A;  3NME A;  1C87 A;  2CNG A;  2G6Z A;  2PQ5 A;  1R6H A;  2QDM A;  2NTA A;  4BJO A;  5IBM A;  5KA1 A;  2ZMM A;  3ZMP A;  5K22 A;  3SME A;  4WU3 A;  2B07 A;  3EU0 A;  1YGU A;  3MOW A;  4D3R A;  4QAP A;  2P4D A;  4KYQ A;  1NNY A;  3BRH A;  3V0J A;  5KAB A;  2I6I A;  1ZC0 A;  2F71 A;  4QAH A;  4RHG A;  3OMH A;  3V0E A;  3ZM2 A;  1Q6N A;  1C85 A;  2CM2 A;  3QCC A;  2VEY A;  1FPR A;  3QCH A;  2NZ6 A;  5EHP A;  3B7O A;  5K9V A;  4RH5 A;  3M4U A;  4RH9 A;  1NZ7 A;  2G59 A;  4QBW A;  3O4T A;  3MMJ A;  2GJT A;  2HC2 A;  2BV5 A;  1YPT A;  1OHD A;  1LQF A;  4ZN5 A;  2H4G A;  2HNQ A;  2QBR A;  5K25 A;  3D42 A;  4WU2 A;  1EEO A;  2F70 A;  4OHH A;  2CJZ A;  2I3R A;  2QCT A;  1SUG A;  1OHC A;  2F6V A;  2J17 A;  5KA8 A;  5K24 A;  1M3G A;  3QKP A;  1KAV A;  3MOZ A;  4HJQ A;  3GXG A;  4RI4 A;  1D5R A;  5BZX A;  3QCB A;  2Q05 A;  4D3P A;  1PA1 A;  5MMZ B;  2I6P A;  1ZCK A;  1C84 A;  1YGR A;  3RZ2 A;  1XXV A;  3V0I A;  3O4U A;  5BUG A;  2I4H A;  5K9W A;  4ICZ A;  3GXH A;  5KAD A;  1G1H A;  2CMB A;  1T49 A;  4HJP A;  2B49 A;  2QCJ A;  3QCJ A;  1BZH A;  3U96 A;  3RO1 A;  2BZL A;  1PYN A;  1Q6S A;  2HY3 A;  3CWE A;  1T48 A;  4GRZ A;  5KA0 A;  1OEU A;  4ERC A;  2BGE A;  1WRM A;  1JLN A;  2CNF A;  4AZ1 A;  4Y14 A;  1G1G A;  4JBC A;  1FPZ A;  1V3A A;  2C7S A;  3BLT A;  1NWL A;  2Y2F A;  2B3O A;  1I57 A;  2SHP A;  2I75 A;  5BZZ A;  1OES A;  4Y2E A;  4S0G A;  1PTV A;  4JNB A;  1ONY A;  1LAR A;  1QZ0 A;  4KYR A;  4YAA A;  2P6X A;  2HVL A;  3D9C A;  5J8R A;  3F81 A;  4GS0 A;  5KA4 A;  1VHR A;  2ESB A;  4HRF A;  2NT2 A;  2F6W A;  2CNI A;  2F6Z A;  3LJ8 A;  2CNH A;  3A5J A;  1L8G A;  3QCI A;  2I4G A;  3S4E A;  2F6T A;  4GWF A;  4WOH A;  1NO6 A;  4RKK A;  1P15 A;  1A5Y A;  3D1Q A;  2PSZ A;  1C86 A;  2I1Y A;  4GFV A;  4QUM A;  1GFY A;  5KA3 A;  5M43 A;  3V0G A;  1NL9 A;  3F9A A;  1PTU A;  4QBE A;  2B4S A;  1YTN A;  2J16 B;  4D3Q A;  2I3U A;  4RI5 A;  2HCM A;  2H02 A;  4IKC A;  3QCM A;  5GTJ A;  3ZM1 A;  1YTS A;  3PS5 A;  1Q6M A;  4KI9 A;  1AAX A;  3QKQ A;  2CMA A;  5I6V A;  3D44 A;  3I36 A;  2PBN A;  2HNP A;  3F41 A;  1I9S A;  4TVV A;  4WTY A;  4H1O A;  2B4P A;  2FH7 A;  4OHE A;  1C88 A;  5KA9 A;  1YTW A;  5HDE A;  2PT0 A;  3H2X A;  1XM2 A;  1OEM X;  1G1F A;  1MKP A;  1EEN A;  3O4S A;  2B4O A;  1OEV A;  4R0T A;  1JF7 A;  2F6Y A;  2I42 A;  3BM8 A;  3F99 A;  4J51 A;  4R0S A;  1G4U S;  4NND A;  1OEO X;  4QUN A;  4H34 A;  1YFO A;  4I8N A;  2J16 A;  1KAK A;  4GE2 A;  1XXP A;  2H4K A;  2QBS A;  2E0T A;  4OHL A;  4NX8 A;  1QXK A;  2A8B A;  2R0B A;  2AHS A;  3S3H A;  2QBP A;  1I9T A;  1XBO A;  2A3K A;  2Q47 A;  2Y96 A;  4NYH A;  5K23 A;  2I6M A;  3S3F A;  1ZZW A;  3BLU A;  1BZJ A;  3QCF A;  4PYH A;  3ZM3 A;  3AWE A;  2I4E A;  3I7Z A;  2OZ5 A;  1Q6T A;  3S3E A;  2I5X A;  1X24 A;  1Q6J A;  4GRY A;  4NWF A;  1BZC A;  2PA5 A;  4MBB A;  3V0H A;  1Q6P A;  1YWF A;  3F9B A;  5IBS A;  3QCL A;  2HC1 A;  2CMC A;  1GWZ A;  2OC3 A;  2JJD A;  4DGX A;  1NWE A;  2I6O A;  2WGP A;  3EMU A;  3CM3 A;  1PA9 A;  1ZCL A;  3QCN A;  3O5X A;  4OHI A;  2C46 A;  2CM3 A;  3O3L A;  3QCD A;  1RPM A;  1G4W R;  2FJM A;  3RGQ A;  2M3V A;  2PI7 A;  5LXQ B;  1G7G A;  2YDU A;  5KA2 A;  5EHR A;  2GP0 A;  3D1O A;  4BPC A;  4DGP A;  3ZV2 A;  4PVG A;  2QEP A;  3I80 A;  1WCH A;  2NV5 A;  2AZR A;  2CFV A;  1U25 A;  2NT7 A;  2CNE A;  3RGO A;  2H4V A; 
#chains in the Genus database with same CATH topology
 3EAX A;  2UUO A;  1L8K A;  2H04 A;  3V0F A;  2CM8 A;  1J4X A;  2BIJ A;  1G7F A;  1YN9 A;  2F00 A;  2ZN7 A;  3V0D A;  2CM7 A;  1U24 A;  3QCE A;  2VEX A;  5KAC A;  2H03 A;  2MBC A;  1FQ1 A;  3EB1 A;  4YR8 B;  3A5K A;  1XRI A;  2OUD A;  1OET A;  3ZM0 A;  4BUC A;  2VEW A;  2RF6 A;  3OLR A;  2VEV A;  2VEU A;  5AWX A;  1WAX A;  3QCG A;  4GFU A;  3AWF A;  2QDP A;  4JMJ A;  2BGD A;  4ZRT A;  3D1H A;  2GWO A;  1PH0 A;  1PTT A;  5KA7 A;  1C83 A;  1Q1M A;  4NWG A;  1PXH A;  3N0A A;  3SR9 A;  4R30 A;  5KAA A;  3AWG A;  3ZMQ A;  3EZZ A;  2NLK A;  4GE6 A;  2HB1 A;  4GE5 A;  2B4U A;  3S3K A;  1ONZ A;  5BX1 A;  4Z6B A;  2HXP A;  2FJN A;  2QBQ A;  2QDC A;  4CVM A;  4B04 A;  4CVK A;  1OHE A;  2DXP A;  1GQQ A;  2F6F A;  4ZI4 A;  2OOQ A;  2GC6 A;  2F46 A;  1PTY A;  3QCK A;  1T4J A;  1RXD A;  3QCZ A;  1YZ4 A;  2AM2 A;  2I6J A;  2UUP A;  5A5F A;  4OHD A;  1U26 A;  3S4O A;  1LYV A;  1ECV A;  4JMK A;  2IMG A;  4RDD A;  3NME A;  4C12 A;  1C87 A;  2CNG A;  2GCA A;  2G6Z A;  2PQ5 A;  1R6H A;  2QDM A;  2NTA A;  4BJO A;  5IBM A;  5KA1 A;  2ZMM A;  3ZMP A;  5K22 A;  3SME A;  2WJP A;  4WU3 A;  2B07 A;  4BUB A;  4ZIY A;  3EU0 A;  1YGU A;  3MOW A;  4D3R A;  4QAP A;  1JBW A;  2P4D A;  4KYQ A;  1NNY A;  3BRH A;  3V0J A;  5KAB A;  2I6I A;  1ZC0 A;  2F71 A;  4QAH A;  2VTE A;  4RHG A;  3OMH A;  4C13 A;  3V0E A;  3ZM2 A;  3HN7 A;  5A5E A;  1Q6N A;  1C85 A;  2CM2 A;  3QCC A;  2VEY A;  1FPR A;  3QCH A;  2NZ6 A;  5EHP A;  3B7O A;  5K9V A;  4RH5 A;  3M4U A;  4RH9 A;  1NZ7 A;  2G59 A;  4QBW A;  3O4T A;  3MMJ A;  2GJT A;  2HC2 A;  1UAG A;  1JBV A;  2BV5 A;  1E8C A;  1YPT A;  1OHD A;  1LQF A;  4ZN5 A;  2H4G A;  2HNQ A;  2QBR A;  5K25 A;  3D42 A;  4WU2 A;  2XPC A;  1EEO A;  2F70 A;  4OHH A;  2CJZ A;  2I3R A;  2QCT A;  1SUG A;  1OHC A;  2F6V A;  2J17 A;  1GQY A;  3MVN A;  5KA8 A;  5K24 A;  1M3G A;  3QKP A;  1W78 A;  1KAV A;  3MOZ A;  4HJQ A;  3GXG A;  4RI4 A;  1D5R A;  5BZX A;  3QCB A;  2Q05 A;  4QDI A;  1PA1 A;  4D3P A;  5MMZ B;  2I6P A;  1ZCK A;  1C84 A;  1YGR A;  3RZ2 A;  2Y66 A;  1XXV A;  3V0I A;  3O4U A;  5BUG A;  2I4H A;  5K9W A;  4ICZ A;  3GXH A;  5KAD A;  1G1H A;  2CMB A;  1T49 A;  4HJP A;  2B49 A;  2QCJ A;  3QCJ A;  1BZH A;  2X5O A;  3U96 A;  3RO1 A;  2BZL A;  1PYN A;  1Q6S A;  2HY3 A;  3CWE A;  2JFH A;  1T48 A;  4GRZ A;  5KA0 A;  1OEU A;  4ERC A;  2BGE A;  1WRM A;  1JLN A;  2CNF A;  3NRS A;  4AZ1 A;  4Y14 A;  1G1G A;  4JBC A;  1FPZ A;  3LK7 A;  1V3A A;  2C7S A;  3BLT A;  1NWL A;  2Y2F A;  2B3O A;  1I57 A;  2SHP A;  2I75 A;  5BZZ A;  1OES A;  2VOS A;  4Y2E A;  4S0G A;  1PTV A;  4JNB A;  1ONY A;  1LAR A;  1QZ0 A;  4KYR A;  1J6U A;  4YAA A;  2UAG A;  2P6X A;  2HVL A;  3D9C A;  5J8R A;  1P31 A;  3F81 A;  4GS0 A;  5KA4 A;  1VHR A;  2ESB A;  4HRF A;  2NT2 A;  2F6W A;  2CNI A;  2F6Z A;  3LJ8 A;  2CNH A;  3A5J A;  1L8G A;  3QCI A;  2I4G A;  3S4E A;  2F6T A;  4GWF A;  4WOH A;  3PYZ A;  1NO6 A;  4RKK A;  1P15 A;  1A5Y A;  3D1Q A;  2PSZ A;  1C86 A;  1O5Z A;  2I1Y A;  4GFV A;  4QUM A;  1GFY A;  5KA3 A;  5M43 A;  3V0G A;  1NL9 A;  3F9A A;  1PTU A;  4QBE A;  2B4S A;  1YTN A;  2J16 B;  4D3Q A;  3ZM6 A;  2I3U A;  4RI5 A;  2HCM A;  2H02 A;  4IKC A;  3QCM A;  2Y68 A;  5GTJ A;  3ZL8 A;  3ZM1 A;  1YTS A;  3PS5 A;  1Q6M A;  4KI9 A;  1AAX A;  3QKQ A;  2CMA A;  5I6V A;  3D44 A;  1W7K A;  2VTD A;  3I36 A;  2PBN A;  2HNP A;  3F41 A;  1I9S A;  4TVV A;  4WTY A;  4H1O A;  2B4P A;  2FH7 A;  2AM1 A;  1C88 A;  4OHE A;  1P3D A;  5KA9 A;  1YTW A;  3UAG A;  1GG4 A;  5HDE A;  2PT0 A;  3H2X A;  1XM2 A;  1FGS A;  1EEH A;  1OEM X;  1G1F A;  1MKP A;  1EEN A;  3O4S A;  2B4O A;  1OEV A;  4R0T A;  1JF7 A;  2F6Y A;  2I42 A;  3BM8 A;  3F99 A;  4J51 A;  4R0S A;  1G4U S;  4NND A;  1OEO X;  4QUN A;  4H34 A;  1YFO A;  4I8N A;  2J16 A;  1KAK A;  2Y1O A;  4GE2 A;  1XXP A;  2H4K A;  2QBS A;  2E0T A;  4OHL A;  4NX8 A;  1QXK A;  2A8B A;  2R0B A;  2AHS A;  3S3H A;  2QBP A;  2JFG A;  1I9T A;  1XBO A;  2A3K A;  2Q47 A;  2VOR A;  3ZM5 A;  1E0D A;  2Y96 A;  4NYH A;  5K23 A;  2I6M A;  3S3F A;  1ZZW A;  3BLU A;  2GCB A;  1BZJ A;  3QCF A;  4PYH A;  3ZM3 A;  3AWE A;  2I4E A;  3I7Z A;  2OZ5 A;  1Q6T A;  3S3E A;  2I5X A;  1X24 A;  1Q6J A;  4GRY A;  4CVL A;  4NWF A;  1BZC A;  2PA5 A;  2XJA A;  4MBB A;  2Y67 A;  2JFF A;  3V0H A;  1Q6P A;  1YWF A;  3F9B A;  5IBS A;  3QCL A;  2HC1 A;  2CMC A;  1GWZ A;  2OC3 A;  2JJD A;  4DGX A;  1NWE A;  2I6O A;  2WGP A;  3EMU A;  3CM3 A;  1PA9 A;  1ZCL A;  3QCN A;  2WTZ A;  3O5X A;  2GC5 A;  4OHI A;  2C46 A;  2CM3 A;  3O3L A;  3QCD A;  4QF5 A;  1RPM A;  1G4W R;  2FJM A;  3RGQ A;  2M3V A;  2PI7 A;  5LXQ B;  1G7G A;  2YDU A;  5KA2 A;  5EHR A;  2GP0 A;  3D1O A;  4BPC A;  4DGP A;  4HV4 A;  3ZV2 A;  4PVG A;  2QEP A;  3I80 A;  1WCH A;  2NV5 A;  2AZR A;  3N2A A;  2CFV A;  1U25 A;  2NT7 A;  4UAG A;  2CNE A;  3RGO A;  2H4V A; 
#chains in the Genus database with same CATH homology
 3EAX A;  1L8K A;  2H04 A;  3V0F A;  2CM8 A;  1J4X A;  2BIJ A;  1G7F A;  1YN9 A;  2ZN7 A;  3V0D A;  2CM7 A;  3QCE A;  1U24 A;  2VEX A;  5KAC A;  2H03 A;  2MBC A;  1FQ1 A;  3EB1 A;  4YR8 B;  3A5K A;  1XRI A;  2OUD A;  1OET A;  3ZM0 A;  2VEW A;  2RF6 A;  3OLR A;  2VEV A;  2VEU A;  5AWX A;  1WAX A;  3QCG A;  4GFU A;  3AWF A;  2QDP A;  4JMJ A;  2BGD A;  4ZRT A;  3D1H A;  2GWO A;  1PH0 A;  1PTT A;  5KA7 A;  1C83 A;  1Q1M A;  4NWG A;  1PXH A;  3N0A A;  3SR9 A;  4R30 A;  5KAA A;  3AWG A;  3ZMQ A;  3EZZ A;  2NLK A;  4GE6 A;  2HB1 A;  4GE5 A;  2B4U A;  3S3K A;  1ONZ A;  5BX1 A;  4Z6B A;  2HXP A;  2FJN A;  2QBQ A;  2QDC A;  4B04 A;  1OHE A;  2DXP A;  2F6F A;  4ZI4 A;  2OOQ A;  2F46 A;  1PTY A;  3QCK A;  1T4J A;  1RXD A;  1YZ4 A;  2I6J A;  4OHD A;  1U26 A;  3S4O A;  1LYV A;  1ECV A;  4JMK A;  2IMG A;  4RDD A;  3NME A;  1C87 A;  2CNG A;  2G6Z A;  2PQ5 A;  1R6H A;  2QDM A;  2NTA A;  4BJO A;  5IBM A;  5KA1 A;  2ZMM A;  3ZMP A;  5K22 A;  3SME A;  4WU3 A;  2B07 A;  3EU0 A;  1YGU A;  3MOW A;  4D3R A;  4QAP A;  2P4D A;  4KYQ A;  1NNY A;  3BRH A;  3V0J A;  5KAB A;  2I6I A;  1ZC0 A;  2F71 A;  4QAH A;  4RHG A;  3OMH A;  3V0E A;  3ZM2 A;  1Q6N A;  1C85 A;  2CM2 A;  3QCC A;  2VEY A;  1FPR A;  3QCH A;  2NZ6 A;  5EHP A;  3B7O A;  5K9V A;  4RH5 A;  3M4U A;  4RH9 A;  1NZ7 A;  2G59 A;  4QBW A;  3O4T A;  3MMJ A;  2GJT A;  2HC2 A;  2BV5 A;  1YPT A;  1OHD A;  1LQF A;  4ZN5 A;  2H4G A;  2HNQ A;  2QBR A;  5K25 A;  3D42 A;  4WU2 A;  1EEO A;  2F70 A;  4OHH A;  2CJZ A;  2I3R A;  2QCT A;  1SUG A;  1OHC A;  2F6V A;  2J17 A;  5KA8 A;  5K24 A;  1M3G A;  3QKP A;  1KAV A;  3MOZ A;  4HJQ A;  3GXG A;  4RI4 A;  1D5R A;  5BZX A;  3QCB A;  2Q05 A;  4D3P A;  1PA1 A;  5MMZ B;  2I6P A;  1ZCK A;  1C84 A;  1YGR A;  3RZ2 A;  1XXV A;  3V0I A;  3O4U A;  5BUG A;  2I4H A;  5K9W A;  4ICZ A;  3GXH A;  5KAD A;  1G1H A;  2CMB A;  1T49 A;  4HJP A;  2B49 A;  2QCJ A;  3QCJ A;  1BZH A;  3U96 A;  3RO1 A;  2BZL A;  1PYN A;  1Q6S A;  2HY3 A;  3CWE A;  1T48 A;  4GRZ A;  5KA0 A;  1OEU A;  4ERC A;  2BGE A;  1WRM A;  1JLN A;  2CNF A;  4AZ1 A;  4Y14 A;  1G1G A;  4JBC A;  1FPZ A;  1V3A A;  2C7S A;  3BLT A;  1NWL A;  2Y2F A;  2B3O A;  1I57 A;  2SHP A;  2I75 A;  5BZZ A;  1OES A;  4Y2E A;  4S0G A;  1PTV A;  4JNB A;  1ONY A;  1LAR A;  1QZ0 A;  4KYR A;  4YAA A;  2P6X A;  2HVL A;  3D9C A;  5J8R A;  3F81 A;  4GS0 A;  5KA4 A;  1VHR A;  2ESB A;  4HRF A;  2NT2 A;  2F6W A;  2CNI A;  2F6Z A;  3LJ8 A;  2CNH A;  3A5J A;  1L8G A;  3QCI A;  2I4G A;  3S4E A;  2F6T A;  4GWF A;  4WOH A;  1NO6 A;  4RKK A;  1P15 A;  1A5Y A;  3D1Q A;  2PSZ A;  1C86 A;  2I1Y A;  4GFV A;  4QUM A;  1GFY A;  5KA3 A;  5M43 A;  3V0G A;  1NL9 A;  3F9A A;  1PTU A;  4QBE A;  2B4S A;  1YTN A;  2J16 B;  4D3Q A;  2I3U A;  4RI5 A;  2HCM A;  2H02 A;  4IKC A;  3QCM A;  5GTJ A;  3ZM1 A;  1YTS A;  3PS5 A;  1Q6M A;  4KI9 A;  1AAX A;  3QKQ A;  2CMA A;  5I6V A;  3D44 A;  3I36 A;  2PBN A;  2HNP A;  3F41 A;  1I9S A;  4TVV A;  4WTY A;  4H1O A;  2B4P A;  2FH7 A;  4OHE A;  1C88 A;  5KA9 A;  1YTW A;  5HDE A;  2PT0 A;  3H2X A;  1XM2 A;  1OEM X;  1G1F A;  1MKP A;  1EEN A;  3O4S A;  2B4O A;  1OEV A;  4R0T A;  1JF7 A;  2F6Y A;  2I42 A;  3BM8 A;  3F99 A;  4J51 A;  4R0S A;  1G4U S;  4NND A;  1OEO X;  4QUN A;  4H34 A;  1YFO A;  4I8N A;  2J16 A;  1KAK A;  4GE2 A;  1XXP A;  2H4K A;  2QBS A;  2E0T A;  4OHL A;  4NX8 A;  1QXK A;  2A8B A;  2R0B A;  2AHS A;  3S3H A;  2QBP A;  1I9T A;  1XBO A;  2A3K A;  2Q47 A;  2Y96 A;  4NYH A;  5K23 A;  2I6M A;  3S3F A;  1ZZW A;  3BLU A;  1BZJ A;  3QCF A;  4PYH A;  3ZM3 A;  3AWE A;  2I4E A;  3I7Z A;  2OZ5 A;  1Q6T A;  3S3E A;  2I5X A;  1X24 A;  1Q6J A;  4GRY A;  4NWF A;  1BZC A;  2PA5 A;  4MBB A;  3V0H A;  1Q6P A;  1YWF A;  3F9B A;  5IBS A;  3QCL A;  2HC1 A;  2CMC A;  1GWZ A;  2OC3 A;  2JJD A;  4DGX A;  1NWE A;  2I6O A;  2WGP A;  3EMU A;  3CM3 A;  1PA9 A;  1ZCL A;  3QCN A;  3O5X A;  4OHI A;  2C46 A;  2CM3 A;  3O3L A;  3QCD A;  1RPM A;  1G4W R;  2FJM A;  3RGQ A;  2M3V A;  2PI7 A;  5LXQ B;  1G7G A;  2YDU A;  5KA2 A;  5EHR A;  2GP0 A;  3D1O A;  4BPC A;  4DGP A;  3ZV2 A;  4PVG A;  2QEP A;  3I80 A;  1WCH A;  2NV5 A;  2AZR A;  2CFV A;  1U25 A;  2NT7 A;  2CNE A;  3RGO A;  2H4V A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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