1G7GA

Human ptp1b catalytic domain complexes with pnu179326
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
total genus 106
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1g7gA00
2HVLA 5K9VA 1ZC0A 3ZMQA 4MBBA 2CJZA 4B04A 2CNHA 2C46A 2F71A 4QBWA 2F6WA 3QCNA 1XBOA 4H34A 1ZCKA 5LXQB 1ONZA 2CMAA 1OETA 1QZ0A 2I3RA 1U24A 4IKCA 4NX8A 1YZ4A 3RO1A 2F6TA 5K23A 2HXPA 5BX1A 2OZ5A 3D9CA 5EHRA 3V0DA 2CM7A 2NT2A 2OUDA 4NYHA 3U96A 3ZM1A 5I6VA 1PTUA 4J51A 4HJPA 4PYHA 2J17A 3O4SA 3V0HA 3MOZA 2GWOA 1LARA 1Q6SA 3D42A 3ZMPA 4WU2A 1X24A 1EEOA 2AZRA 1YWFA 2I75A 1NNYA 1PXHA 4H1OA 4R0SA 5AWXA 3S3HA 1KAVA 1JLNA 1PTVA 2PQ5A 1T48A 2VEVA 2PBNA 2CM2A 2B07A 5KA2A 3S4EA 5KADA 1ZZWA 3H2XA 1EENA 3A5KA 2H04A 5J8RA 3F99A 3QCLA 4DGPA 1D5RA 2Q47A 2BGEA 4JMJA 3F81A 2CFVA 3EAXA 2ZMMA 2CNGA 3GXHA 3PS5A 3RGOA 3SR9A 2HNPA 1C84A 1YFOA 5HDEA 4NNDA 2YDUA 1PYNA 3QCIA 1YPTA 3O3LA 4ZN5A 4GFUA 1OHCA 1C85A 3QCKA 2F70A 5KA0A 1A5YA 5KA8A 1NWLA 2NTAA 1Q1MA 3V0IA 1YTNA 2B3OA 1FQ1A 2QDCA 4I8NA 2E0TA 1ONYA 4DGXA 1P15A 5BUGA 2H4GA 2I6IA 3QCHA 1T4JA 4D3RA 4RH5A 3CWEA 5KA3A 1BZCA 5KACA 1XRIA 3QKPA 4BPCA 2G6ZA 1SUGA 3CM3A 1G7GA 2NLKA 1NL9A 1Q6JA 3BM8A 5KABA 2SHPA 4HJQA 2A8BA 1OEMX 2G59A 3F41A 2H4KA 1ECVA 2NZ6A 2QBRA 2R0BA 2HC1A 1YTSA 3BLTA 1LYVA 2P4DA 4RH9A 2J16A 3V0GA 5KA1A 1R6HA 3O5XA 2BGDA 4Y14A 1T49A 2MBCA 3I80A 2A3KA 2I6MA 3F9BA 2F6VA 4OHDA 2I1YA 3QCCA 3D1QA 2B4SA 3EMUA 3S3EA 2PA5A 1YGRA 2ZN7A 2Y96A 1RPMA 2I4EA 3S4OA 2B4UA 3OLRA 4JBCA 4QBEA 2FJNA 1G7FA 4D3PA 1PA1A 1VHRA 3S3KA 1G1GA 2PT0A 3QCBA 4KI9A 5KA9A 3I7ZA 2H03A 2CNFA 1G4US 1G1FA 3QCFA 1WRMA 2OC3A 3QCGA 2I5XA 2QBSA 1FPRA 4GFVA 1PTYA 5K22A 1U25A 5GTJA 2J16B 1ZCLA 4OHIA 2I6OA 3EZZA 2HC2A 3O4TA 5KA4A 5IBMA 1JF7A 3MMJA 2PI7A 2Y2FA 5K25A 4NWGA 2JJDA 3S3FA 4RI4A 2BV5A 4RKKA 2I3UA 3QCMA 4ERCA 2HB1A 1KAKA 2QDMA 2QEPA 1U26A 2OOQA 2CNEA 4JMKA 1J4XA 2H02A 4RI5A 4R30A 2Q05A 4WTYA 4QUNA 3EU0A 1BZJA 2GJTA 4R0TA 1G1HA 1OEUA 4GE6A 2HY3A 4ZRTA 1L8GA 1Q6NA 2GP0A 4GS0A 1C87A 3AWFA 1PH0A 1GFYA 2CM3A 2B49A 1PTTA 3QCDA 1XM2A 2FH7A 5IBSA 2M3VA 4WU3A 2NT7A 4NWFA 4GWFA 2BZLA 3ZM2A 2CNIA 3V0JA 4KYRA 2CM8A 3OMHA 2NV5A 5K9WA 2I42A 3BRHA 4TVVA 4YAAA 2C7SA 4S0GA 3RGQA 2B4OA 1RXDA 3SMEA 5M43A 1MKPA 2I6JA 1WCHA 4QUMA 3D44A 4KYQA 1OHDA 1Q6PA 1FPZA 2CMCA 5EHPA 4GE2A 1M3GA 4Y2EA 5KA7A 2F6YA 2VEWA 1GWZA 2QCJA 1I9TA 3ZM0A 2VEXA 1XXVA 5BZXA 1YN9A 2QBQA 3M4UA 3O4UA 2H4VA 4AZ1A 1L8KA 1V3AA 2WGPA 4QAPA 3NMEA 2RF6A 2AHSA 3LJ8A 4JNBA 3AWEA 1YTWA 3EB1A 3QCJA 1OESA 3A5JA 3RZ2A 1C83A 3F9AA 1NZ7A 2VEYA 4PVGA 2QBPA 3I36A 4OHLA 4RDDA 1OEOX 1LQFA 1YGUA 2HNQA 4OHHA 1BZHA 1XXPA 4D3QA 2HCMA 4GRZA 3MOWA 2I4HA 2PSZA 3V0EA 2B4PA 2ESBA 4BJOA 3GXGA 1I9SA 1C88A 3D1OA 4OHEA 2I6PA 2QCTA 3QKQA 2F6FA 2IMGA 3AWGA 2F6ZA 1AAXA 4ICZA 1PA9A 3B7OA 4ZI4A 4GRYA 2F46A 3ZM3A 4WOHA 2QDPA 2FJMA 4YR8B 5K24A 1NO6A 1WAXA 3N0AA 1NWEA 4Z6BA 4QAHA 2P6XA 1G4WR 5BZZA 1QXKA 1Q6MA 1OHEA 1Q6TA 4RHGA 3ZV2A 3V0FA 2BIJA 3QCEA 3D1HA 2DXPA 2I4GA 3BLUA 2VEUA 4GE5A 5KAAA 4HRFA 1C86A 2CMBA 5MMZB 1I57A 1OEVA
chains in the Genus database with same CATH superfamily
2HVLA 5K9VA 1ZC0A 3ZMQA 4MBBA 2CJZA 2GC5A 4B04A 2CNHA 2C46A 1GQYA 2F71A 4QBWA 2F6WA 3QCNA 1XBOA 4H34A 1ZCKA 2F00A 1GQQA 2GCBA 5LXQB 1ONZA 2CMAA 1OETA 1QZ0A 1FGSA 2I3RA 1U24A 4IKCA 4NX8A 1YZ4A 3RO1A 2F6TA 5K23A 3LK7A 2HXPA 5BX1A 2OZ5A 3D9CA 5EHRA 3V0DA 2CM7A 2NT2A 2OUDA 4NYHA 2UUOA 3U96A 3ZM1A 5A5EA 5I6VA 1PTUA 4J51A 4HJPA 1UAGA 4PYHA 2J17A 3O4SA 3V0HA 4C13A 3MOZA 4CVMA 2GWOA 1LARA 1Q6SA 3D42A 3ZMPA 4WU2A 1X24A 1EEOA 2AZRA 1YWFA 2I75A 1NNYA 1PXHA 4H1OA 4R0SA 5AWXA 3S3HA 1KAVA 1JLNA 1PTVA 2PQ5A 1T48A 3NRSA 2VEVA 2PBNA 2CM2A 2B07A 5KA2A 3S4EA 5KADA 1ZZWA 3H2XA 1EENA 3A5KA 2H04A 4QF5A 5J8RA 3F99A 3QCLA 4DGPA 1D5RA 2Q47A 2BGEA 4JMJA 3UAGA 3F81A 4CVKA 2CFVA 3EAXA 2ZMMA 2CNGA 3GXHA 3PS5A 3RGOA 3SR9A 3HN7A 2HNPA 1C84A 1YFOA 5HDEA 4NNDA 2YDUA 1PYNA 3QCIA 1YPTA 3O3LA 4ZN5A 4GFUA 1OHCA 1C85A 3QCKA 2F70A 5KA0A 1A5YA 5KA8A 1NWLA 2NTAA 1Q1MA 3V0IA 1YTNA 2B3OA 1FQ1A 2QDCA 4I8NA 4C12A 2E0TA 1ONYA 2JFHA 4DGXA 1P15A 1E0DA 5BUGA 2H4GA 2I6IA 1JBVA 3QCHA 1T4JA 4D3RA 4RH5A 3CWEA 5KA3A 1BZCA 2XPCA 2GC6A 5KACA 1XRIA 3QKPA 4BPCA 2G6ZA 1SUGA 1GG4A 3CM3A 1G7GA 2Y66A 2NLKA 1NL9A 1Q6JA 3BM8A 3N2AA 5KABA 2SHPA 4HJQA 2A8BA 1OEMX 2G59A 3F41A 2H4KA 1ECVA 2NZ6A 2QBRA 2R0BA 2HC1A 1YTSA 3BLTA 1LYVA 2P4DA 4RH9A 2J16A 3V0GA 5KA1A 1R6HA 3O5XA 2BGDA 4Y14A 1T49A 2MBCA 3I80A 2A3KA 2I6MA 3F9BA 1W7KA 2F6VA 4OHDA 2I1YA 3QCCA 2VTEA 3D1QA 2B4SA 3EMUA 4ZIYA 3S3EA 2PA5A 1YGRA 2ZN7A 2Y96A 1RPMA 2I4EA 3S4OA 2AM2A 2B4UA 3OLRA 4JBCA 3ZL8A 4QBEA 2FJNA 1G7FA 4D3PA 3PYZA 1PA1A 1VHRA 3S3KA 1G1GA 2PT0A 3ZM5A 4QDIA 3QCBA 4KI9A 5KA9A 3I7ZA 2H03A 2CNFA 1G4US 1G1FA 3QCFA 1WRMA 2OC3A 2WJPA 3QCGA 2I5XA 2QBSA 1FPRA 4GFVA 1PTYA 5K22A 1U25A 5GTJA 2J16B 1ZCLA 4OHIA 2I6OA 3EZZA 2HC2A 3O4TA 5KA4A 5IBMA 1JF7A 3MMJA 2PI7A 1JBWA 1P31A 2Y2FA 5K25A 4NWGA 2JJDA 2VTDA 4RI4A 4UAGA 3S3FA 2BV5A 1O5ZA 4RKKA 2JFGA 2I3UA 3QCMA 4ERCA 2Y1OA 2HB1A 1KAKA 2QDMA 2QEPA 1U26A 2OOQA 2CNEA 4JMKA 1J4XA 2H02A 4RI5A 4R30A 2Q05A 3ZM6A 4WTYA 4QUNA 3EU0A 1BZJA 2GJTA 4R0TA 4BUBA 1G1HA 2Y67A 1OEUA 4GE6A 2HY3A 2XJAA 4ZRTA 1L8GA 1Q6NA 2GP0A 4GS0A 2VORA 1C87A 3AWFA 1PH0A 1GFYA 2CM3A 2B49A 1PTTA 1XM2A 3MVNA 2FH7A 3QCDA 5IBSA 5A5FA 2M3VA 4WU3A 2NT7A 4NWFA 4GWFA 2BZLA 3ZM2A 2CNIA 3V0JA 4KYRA 2CM8A 3OMHA 2NV5A 5K9WA 2I42A 3BRHA 4TVVA 4YAAA 2C7SA 4HV4A 4S0GA 3RGQA 2B4OA 1RXDA 3SMEA 2VOSA 1MKPA 2I6JA 1W78A 1WCHA 4QUMA 5M43A 3D44A 4KYQA 1EEHA 1OHDA 1J6UA 4BUCA 1Q6PA 1FPZA 2CMCA 5EHPA 4GE2A 1E8CA 1M3GA 3QCZA 4Y2EA 5KA7A 2F6YA 2UAGA 2VEWA 1GWZA 2QCJA 1I9TA 3ZM0A 2VEXA 1XXVA 5BZXA 1YN9A 2QBQA 3M4UA 3O4UA 2H4VA 4AZ1A 1L8KA 1V3AA 2WGPA 4QAPA 3NMEA 2RF6A 2AHSA 3LJ8A 4CVLA 4JNBA 3AWEA 1YTWA 3EB1A 3QCJA 1OESA 3A5JA 3RZ2A 1C83A 3F9AA 1NZ7A 2VEYA 4PVGA 1P3DA 2QBPA 3I36A 4OHLA 1OEOX 4RDDA 2Y68A 1LQFA 1YGUA 2HNQA 4OHHA 1BZHA 1XXPA 4D3QA 2HCMA 4GRZA 3MOWA 2I4HA 2PSZA 3V0EA 2B4PA 2ESBA 4BJOA 3GXGA 2GCAA 2JFFA 1I9SA 1C88A 3D1OA 2X5OA 4OHEA 2I6PA 2QCTA 3QKQA 2F6FA 2IMGA 3AWGA 2F6ZA 1AAXA 4ICZA 1PA9A 3B7OA 4ZI4A 4GRYA 2F46A 3ZM3A 4WOHA 2QDPA 2FJMA 4YR8B 2UUPA 5K24A 1NO6A 1WAXA 3N0AA 1NWEA 2WTZA 4Z6BA 2AM1A 4QAHA 2P6XA 1G4WR 5BZZA 1QXKA 1Q6MA 1OHEA 1Q6TA 4RHGA 3ZV2A 3V0FA 2BIJA 3QCEA 3D1HA 2DXPA 2I4GA 3BLUA 2VEUA 4GE5A 5KAAA 4HRFA 1C86A 2CMBA 5MMZB 1I57A 1OEVA
chains in the Genus database with same CATH topology
2HVLA 5K9VA 1ZC0A 3ZMQA 4MBBA 2CJZA 4B04A 2CNHA 2C46A 2F71A 4QBWA 2F6WA 3QCNA 1XBOA 4H34A 1ZCKA 5LXQB 1ONZA 2CMAA 1OETA 1QZ0A 2I3RA 1U24A 4IKCA 4NX8A 1YZ4A 3RO1A 2F6TA 5K23A 2HXPA 5BX1A 2OZ5A 3D9CA 5EHRA 3V0DA 2CM7A 2NT2A 2OUDA 4NYHA 3U96A 3ZM1A 5I6VA 1PTUA 4J51A 4HJPA 4PYHA 2J17A 3O4SA 3V0HA 3MOZA 2GWOA 1LARA 1Q6SA 3D42A 3ZMPA 4WU2A 1X24A 1EEOA 2AZRA 1YWFA 2I75A 1NNYA 1PXHA 4H1OA 4R0SA 5AWXA 3S3HA 1KAVA 1JLNA 1PTVA 2PQ5A 1T48A 2VEVA 2PBNA 2CM2A 2B07A 5KA2A 3S4EA 5KADA 1ZZWA 3H2XA 1EENA 3A5KA 2H04A 5J8RA 3F99A 3QCLA 4DGPA 1D5RA 2Q47A 2BGEA 4JMJA 3F81A 2CFVA 3EAXA 2ZMMA 2CNGA 3GXHA 3PS5A 3RGOA 3SR9A 2HNPA 1C84A 1YFOA 5HDEA 4NNDA 2YDUA 1PYNA 3QCIA 1YPTA 3O3LA 4ZN5A 4GFUA 1OHCA 1C85A 3QCKA 2F70A 5KA0A 1A5YA 5KA8A 1NWLA 2NTAA 1Q1MA 3V0IA 1YTNA 2B3OA 1FQ1A 2QDCA 4I8NA 2E0TA 1ONYA 4DGXA 1P15A 5BUGA 2H4GA 2I6IA 3QCHA 1T4JA 4D3RA 4RH5A 3CWEA 5KA3A 1BZCA 5KACA 1XRIA 3QKPA 4BPCA 2G6ZA 1SUGA 3CM3A 1G7GA 2NLKA 1NL9A 1Q6JA 3BM8A 5KABA 2SHPA 4HJQA 2A8BA 1OEMX 2G59A 3F41A 2H4KA 1ECVA 2NZ6A 2QBRA 2R0BA 2HC1A 1YTSA 3BLTA 1LYVA 2P4DA 4RH9A 2J16A 3V0GA 5KA1A 1R6HA 3O5XA 2BGDA 4Y14A 1T49A 2MBCA 3I80A 2A3KA 2I6MA 3F9BA 2F6VA 4OHDA 2I1YA 3QCCA 3D1QA 2B4SA 3EMUA 3S3EA 2PA5A 1YGRA 2ZN7A 2Y96A 1RPMA 2I4EA 3S4OA 2B4UA 3OLRA 4JBCA 4QBEA 2FJNA 1G7FA 4D3PA 1PA1A 1VHRA 3S3KA 1G1GA 2PT0A 3QCBA 4KI9A 5KA9A 3I7ZA 2H03A 2CNFA 1G4US 1G1FA 3QCFA 1WRMA 2OC3A 3QCGA 2I5XA 2QBSA 1FPRA 4GFVA 1PTYA 5K22A 1U25A 5GTJA 2J16B 1ZCLA 4OHIA 2I6OA 3EZZA 2HC2A 3O4TA 5KA4A 5IBMA 1JF7A 3MMJA 2PI7A 2Y2FA 5K25A 4NWGA 2JJDA 3S3FA 4RI4A 2BV5A 4RKKA 2I3UA 3QCMA 4ERCA 2HB1A 1KAKA 2QDMA 2QEPA 1U26A 2OOQA 2CNEA 4JMKA 1J4XA 2H02A 4RI5A 4R30A 2Q05A 4WTYA 4QUNA 3EU0A 1BZJA 2GJTA 4R0TA 1G1HA 1OEUA 4GE6A 2HY3A 4ZRTA 1L8GA 1Q6NA 2GP0A 4GS0A 1C87A 3AWFA 1PH0A 1GFYA 2CM3A 2B49A 1PTTA 3QCDA 1XM2A 2FH7A 5IBSA 2M3VA 4WU3A 2NT7A 4NWFA 4GWFA 2BZLA 3ZM2A 2CNIA 3V0JA 4KYRA 2CM8A 3OMHA 2NV5A 5K9WA 2I42A 3BRHA 4TVVA 4YAAA 2C7SA 4S0GA 3RGQA 2B4OA 1RXDA 3SMEA 5M43A 1MKPA 2I6JA 1WCHA 4QUMA 3D44A 4KYQA 1OHDA 1Q6PA 1FPZA 2CMCA 5EHPA 4GE2A 1M3GA 4Y2EA 5KA7A 2F6YA 2VEWA 1GWZA 2QCJA 1I9TA 3ZM0A 2VEXA 1XXVA 5BZXA 1YN9A 2QBQA 3M4UA 3O4UA 2H4VA 4AZ1A 1L8KA 1V3AA 2WGPA 4QAPA 3NMEA 2RF6A 2AHSA 3LJ8A 4JNBA 3AWEA 1YTWA 3EB1A 3QCJA 1OESA 3A5JA 3RZ2A 1C83A 3F9AA 1NZ7A 2VEYA 4PVGA 2QBPA 3I36A 4OHLA 4RDDA 1OEOX 1LQFA 1YGUA 2HNQA 4OHHA 1BZHA 1XXPA 4D3QA 2HCMA 4GRZA 3MOWA 2I4HA 2PSZA 3V0EA 2B4PA 2ESBA 4BJOA 3GXGA 1I9SA 1C88A 3D1OA 4OHEA 2I6PA 2QCTA 3QKQA 2F6FA 2IMGA 3AWGA 2F6ZA 1AAXA 4ICZA 1PA9A 3B7OA 4ZI4A 4GRYA 2F46A 3ZM3A 4WOHA 2QDPA 2FJMA 4YR8B 5K24A 1NO6A 1WAXA 3N0AA 1NWEA 4Z6BA 4QAHA 2P6XA 1G4WR 5BZZA 1QXKA 1Q6MA 1OHEA 1Q6TA 4RHGA 3ZV2A 3V0FA 2BIJA 3QCEA 3D1HA 2DXPA 2I4GA 3BLUA 2VEUA 4GE5A 5KAAA 4HRFA 1C86A 2CMBA 5MMZB 1I57A 1OEVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HVL A;  5K9V A;  1ZC0 A;  3ZMQ A;  4MBB A;  2CJZ A;  4B04 A;  2CNH A;  2C46 A;  2F71 A;  4QBW A;  2F6W A;  3QCN A;  1XBO A;  4H34 A;  1ZCK A;  5LXQ B;  1ONZ A;  2CMA A;  1OET A;  1QZ0 A;  2I3R A;  1U24 A;  4IKC A;  4NX8 A;  1YZ4 A;  3RO1 A;  2F6T A;  5K23 A;  2HXP A;  5BX1 A;  2OZ5 A;  3D9C A;  5EHR A;  3V0D A;  2CM7 A;  2NT2 A;  2OUD A;  4NYH A;  3U96 A;  3ZM1 A;  5I6V A;  1PTU A;  4J51 A;  4HJP A;  4PYH A;  2J17 A;  3O4S A;  3V0H A;  3MOZ A;  2GWO A;  1LAR A;  1Q6S A;  3D42 A;  3ZMP A;  4WU2 A;  1X24 A;  1EEO A;  2AZR A;  1YWF A;  2I75 A;  1NNY A;  1PXH A;  4H1O A;  4R0S A;  5AWX A;  3S3H A;  1KAV A;  1JLN A;  1PTV A;  2PQ5 A;  1T48 A;  2VEV A;  2PBN A;  2CM2 A;  2B07 A;  5KA2 A;  3S4E A;  5KAD A;  1ZZW A;  3H2X A;  1EEN A;  3A5K A;  2H04 A;  5J8R A;  3F99 A;  3QCL A;  4DGP A;  1D5R A;  2Q47 A;  2BGE A;  4JMJ A;  3F81 A;  2CFV A;  3EAX A;  2ZMM A;  2CNG A;  3GXH A;  3PS5 A;  3RGO A;  3SR9 A;  2HNP A;  1C84 A;  1YFO A;  5HDE A;  4NND A;  2YDU A;  1PYN A;  3QCI A;  1YPT A;  3O3L A;  4ZN5 A;  4GFU A;  1OHC A;  1C85 A;  3QCK A;  2F70 A;  5KA0 A;  1A5Y A;  5KA8 A;  1NWL A;  2NTA A;  1Q1M A;  3V0I A;  1YTN A;  2B3O A;  1FQ1 A;  2QDC A;  4I8N A;  2E0T A;  1ONY A;  4DGX A;  1P15 A;  5BUG A;  2H4G A;  2I6I A;  3QCH A;  1T4J A;  4D3R A;  4RH5 A;  3CWE A;  5KA3 A;  1BZC A;  5KAC A;  1XRI A;  3QKP A;  4BPC A;  2G6Z A;  1SUG A;  3CM3 A;  1G7G A;  2NLK A;  1NL9 A;  1Q6J A;  3BM8 A;  5KAB A;  2SHP A;  4HJQ A;  2A8B A;  1OEM X;  2G59 A;  3F41 A;  2H4K A;  1ECV A;  2NZ6 A;  2QBR A;  2R0B A;  2HC1 A;  1YTS A;  3BLT A;  1LYV A;  2P4D A;  4RH9 A;  2J16 A;  3V0G A;  5KA1 A;  1R6H A;  3O5X A;  2BGD A;  4Y14 A;  1T49 A;  2MBC A;  3I80 A;  2A3K A;  2I6M A;  3F9B A;  2F6V A;  4OHD A;  2I1Y A;  3QCC A;  3D1Q A;  2B4S A;  3EMU A;  3S3E A;  2PA5 A;  1YGR A;  2ZN7 A;  2Y96 A;  1RPM A;  2I4E A;  3S4O A;  2B4U A;  3OLR A;  4JBC A;  4QBE A;  2FJN A;  1G7F A;  4D3P A;  1PA1 A;  1VHR A;  3S3K A;  1G1G A;  2PT0 A;  3QCB A;  4KI9 A;  5KA9 A;  3I7Z A;  2H03 A;  2CNF A;  1G4U S;  1G1F A;  3QCF A;  1WRM A;  2OC3 A;  3QCG A;  2I5X A;  2QBS A;  1FPR A;  4GFV A;  1PTY A;  5K22 A;  1U25 A;  5GTJ A;  2J16 B;  1ZCL A;  4OHI A;  2I6O A;  3EZZ A;  2HC2 A;  3O4T A;  5KA4 A;  5IBM A;  1JF7 A;  3MMJ A;  2PI7 A;  2Y2F A;  5K25 A;  4NWG A;  2JJD A;  3S3F A;  4RI4 A;  2BV5 A;  4RKK A;  2I3U A;  3QCM A;  4ERC A;  2HB1 A;  1KAK A;  2QDM A;  2QEP A;  1U26 A;  2OOQ A;  2CNE A;  4JMK A;  1J4X A;  2H02 A;  4RI5 A;  4R30 A;  2Q05 A;  4WTY A;  4QUN A;  3EU0 A;  1BZJ A;  2GJT A;  4R0T A;  1G1H A;  1OEU A;  4GE6 A;  2HY3 A;  4ZRT A;  1L8G A;  1Q6N A;  2GP0 A;  4GS0 A;  1C87 A;  3AWF A;  1PH0 A;  1GFY A;  2CM3 A;  2B49 A;  1PTT A;  3QCD A;  1XM2 A;  2FH7 A;  5IBS A;  2M3V A;  4WU3 A;  2NT7 A;  4NWF A;  4GWF A;  2BZL A;  3ZM2 A;  2CNI A;  3V0J A;  4KYR A;  2CM8 A;  3OMH A;  2NV5 A;  5K9W A;  2I42 A;  3BRH A;  4TVV A;  4YAA A;  2C7S A;  4S0G A;  3RGQ A;  2B4O A;  1RXD A;  3SME A;  5M43 A;  1MKP A;  2I6J A;  1WCH A;  4QUM A;  3D44 A;  4KYQ A;  1OHD A;  1Q6P A;  1FPZ A;  2CMC A;  5EHP A;  4GE2 A;  1M3G A;  4Y2E A;  5KA7 A;  2F6Y A;  2VEW A;  1GWZ A;  2QCJ A;  1I9T A;  3ZM0 A;  2VEX A;  1XXV A;  5BZX A;  1YN9 A;  2QBQ A;  3M4U A;  3O4U A;  2H4V A;  4AZ1 A;  1L8K A;  1V3A A;  2WGP A;  4QAP A;  3NME A;  2RF6 A;  2AHS A;  3LJ8 A;  4JNB A;  3AWE A;  1YTW A;  3EB1 A;  3QCJ A;  1OES A;  3A5J A;  3RZ2 A;  1C83 A;  3F9A A;  1NZ7 A;  2VEY A;  4PVG A;  2QBP A;  3I36 A;  4OHL A;  4RDD A;  1OEO X;  1LQF A;  1YGU A;  2HNQ A;  4OHH A;  1BZH A;  1XXP A;  4D3Q A;  2HCM A;  4GRZ A;  3MOW A;  2I4H A;  2PSZ A;  3V0E A;  2B4P A;  2ESB A;  4BJO A;  3GXG A;  1I9S A;  1C88 A;  3D1O A;  4OHE A;  2I6P A;  2QCT A;  3QKQ A;  2F6F A;  2IMG A;  3AWG A;  2F6Z A;  1AAX A;  4ICZ A;  1PA9 A;  3B7O A;  4ZI4 A;  4GRY A;  2F46 A;  3ZM3 A;  4WOH A;  2QDP A;  2FJM A;  4YR8 B;  5K24 A;  1NO6 A;  1WAX A;  3N0A A;  1NWE A;  4Z6B A;  4QAH A;  2P6X A;  1G4W R;  5BZZ A;  1QXK A;  1Q6M A;  1OHE A;  1Q6T A;  4RHG A;  3ZV2 A;  3V0F A;  2BIJ A;  3QCE A;  3D1H A;  2DXP A;  2I4G A;  3BLU A;  2VEU A;  4GE5 A;  5KAA A;  4HRF A;  1C86 A;  2CMB A;  5MMZ B;  1I57 A;  1OEV A; 
#chains in the Genus database with same CATH topology
 2HVL A;  5K9V A;  1ZC0 A;  3ZMQ A;  4MBB A;  2CJZ A;  2GC5 A;  4B04 A;  2CNH A;  2C46 A;  1GQY A;  2F71 A;  4QBW A;  2F6W A;  3QCN A;  1XBO A;  4H34 A;  1ZCK A;  2F00 A;  1GQQ A;  2GCB A;  5LXQ B;  1ONZ A;  2CMA A;  1OET A;  1QZ0 A;  1FGS A;  2I3R A;  1U24 A;  4IKC A;  4NX8 A;  1YZ4 A;  3RO1 A;  2F6T A;  5K23 A;  3LK7 A;  2HXP A;  5BX1 A;  2OZ5 A;  3D9C A;  5EHR A;  3V0D A;  2CM7 A;  2NT2 A;  2OUD A;  4NYH A;  2UUO A;  3U96 A;  3ZM1 A;  5A5E A;  5I6V A;  1PTU A;  4J51 A;  4HJP A;  1UAG A;  4PYH A;  2J17 A;  3O4S A;  3V0H A;  4C13 A;  3MOZ A;  4CVM A;  2GWO A;  1LAR A;  1Q6S A;  3D42 A;  3ZMP A;  4WU2 A;  1X24 A;  1EEO A;  2AZR A;  1YWF A;  2I75 A;  1NNY A;  1PXH A;  4H1O A;  4R0S A;  5AWX A;  3S3H A;  1KAV A;  1JLN A;  1PTV A;  2PQ5 A;  1T48 A;  3NRS A;  2VEV A;  2PBN A;  2CM2 A;  2B07 A;  5KA2 A;  3S4E A;  5KAD A;  1ZZW A;  3H2X A;  1EEN A;  3A5K A;  2H04 A;  4QF5 A;  5J8R A;  3F99 A;  3QCL A;  4DGP A;  1D5R A;  2Q47 A;  2BGE A;  4JMJ A;  3UAG A;  3F81 A;  4CVK A;  2CFV A;  3EAX A;  2ZMM A;  2CNG A;  3GXH A;  3PS5 A;  3RGO A;  3SR9 A;  3HN7 A;  2HNP A;  1C84 A;  1YFO A;  5HDE A;  4NND A;  2YDU A;  1PYN A;  3QCI A;  1YPT A;  3O3L A;  4ZN5 A;  4GFU A;  1OHC A;  1C85 A;  3QCK A;  2F70 A;  5KA0 A;  1A5Y A;  5KA8 A;  1NWL A;  2NTA A;  1Q1M A;  3V0I A;  1YTN A;  2B3O A;  1FQ1 A;  2QDC A;  4I8N A;  4C12 A;  2E0T A;  1ONY A;  2JFH A;  4DGX A;  1P15 A;  1E0D A;  5BUG A;  2H4G A;  2I6I A;  1JBV A;  3QCH A;  1T4J A;  4D3R A;  4RH5 A;  3CWE A;  5KA3 A;  1BZC A;  2XPC A;  2GC6 A;  5KAC A;  1XRI A;  3QKP A;  4BPC A;  2G6Z A;  1SUG A;  1GG4 A;  3CM3 A;  1G7G A;  2Y66 A;  2NLK A;  1NL9 A;  1Q6J A;  3BM8 A;  3N2A A;  5KAB A;  2SHP A;  4HJQ A;  2A8B A;  1OEM X;  2G59 A;  3F41 A;  2H4K A;  1ECV A;  2NZ6 A;  2QBR A;  2R0B A;  2HC1 A;  1YTS A;  3BLT A;  1LYV A;  2P4D A;  4RH9 A;  2J16 A;  3V0G A;  5KA1 A;  1R6H A;  3O5X A;  2BGD A;  4Y14 A;  1T49 A;  2MBC A;  3I80 A;  2A3K A;  2I6M A;  3F9B A;  1W7K A;  2F6V A;  4OHD A;  2I1Y A;  3QCC A;  2VTE A;  3D1Q A;  2B4S A;  3EMU A;  4ZIY A;  3S3E A;  2PA5 A;  1YGR A;  2ZN7 A;  2Y96 A;  1RPM A;  2I4E A;  3S4O A;  2AM2 A;  2B4U A;  3OLR A;  4JBC A;  3ZL8 A;  4QBE A;  2FJN A;  1G7F A;  4D3P A;  3PYZ A;  1PA1 A;  1VHR A;  3S3K A;  1G1G A;  2PT0 A;  3ZM5 A;  4QDI A;  3QCB A;  4KI9 A;  5KA9 A;  3I7Z A;  2H03 A;  2CNF A;  1G4U S;  1G1F A;  3QCF A;  1WRM A;  2OC3 A;  2WJP A;  3QCG A;  2I5X A;  2QBS A;  1FPR A;  4GFV A;  1PTY A;  5K22 A;  1U25 A;  5GTJ A;  2J16 B;  1ZCL A;  4OHI A;  2I6O A;  3EZZ A;  2HC2 A;  3O4T A;  5KA4 A;  5IBM A;  1JF7 A;  3MMJ A;  2PI7 A;  1JBW A;  1P31 A;  2Y2F A;  5K25 A;  4NWG A;  2JJD A;  2VTD A;  4RI4 A;  4UAG A;  3S3F A;  2BV5 A;  1O5Z A;  4RKK A;  2JFG A;  2I3U A;  3QCM A;  4ERC A;  2Y1O A;  2HB1 A;  1KAK A;  2QDM A;  2QEP A;  1U26 A;  2OOQ A;  2CNE A;  4JMK A;  1J4X A;  2H02 A;  4RI5 A;  4R30 A;  2Q05 A;  3ZM6 A;  4WTY A;  4QUN A;  3EU0 A;  1BZJ A;  2GJT A;  4R0T A;  4BUB A;  1G1H A;  2Y67 A;  1OEU A;  4GE6 A;  2HY3 A;  2XJA A;  4ZRT A;  1L8G A;  1Q6N A;  2GP0 A;  4GS0 A;  2VOR A;  1C87 A;  3AWF A;  1PH0 A;  1GFY A;  2CM3 A;  2B49 A;  1PTT A;  1XM2 A;  3MVN A;  2FH7 A;  3QCD A;  5IBS A;  5A5F A;  2M3V A;  4WU3 A;  2NT7 A;  4NWF A;  4GWF A;  2BZL A;  3ZM2 A;  2CNI A;  3V0J A;  4KYR A;  2CM8 A;  3OMH A;  2NV5 A;  5K9W A;  2I42 A;  3BRH A;  4TVV A;  4YAA A;  2C7S A;  4HV4 A;  4S0G A;  3RGQ A;  2B4O A;  1RXD A;  3SME A;  2VOS A;  1MKP A;  2I6J A;  1W78 A;  1WCH A;  4QUM A;  5M43 A;  3D44 A;  4KYQ A;  1EEH A;  1OHD A;  1J6U A;  4BUC A;  1Q6P A;  1FPZ A;  2CMC A;  5EHP A;  4GE2 A;  1E8C A;  1M3G A;  3QCZ A;  4Y2E A;  5KA7 A;  2F6Y A;  2UAG A;  2VEW A;  1GWZ A;  2QCJ A;  1I9T A;  3ZM0 A;  2VEX A;  1XXV A;  5BZX A;  1YN9 A;  2QBQ A;  3M4U A;  3O4U A;  2H4V A;  4AZ1 A;  1L8K A;  1V3A A;  2WGP A;  4QAP A;  3NME A;  2RF6 A;  2AHS A;  3LJ8 A;  4CVL A;  4JNB A;  3AWE A;  1YTW A;  3EB1 A;  3QCJ A;  1OES A;  3A5J A;  3RZ2 A;  1C83 A;  3F9A A;  1NZ7 A;  2VEY A;  4PVG A;  1P3D A;  2QBP A;  3I36 A;  4OHL A;  1OEO X;  4RDD A;  2Y68 A;  1LQF A;  1YGU A;  2HNQ A;  4OHH A;  1BZH A;  1XXP A;  4D3Q A;  2HCM A;  4GRZ A;  3MOW A;  2I4H A;  2PSZ A;  3V0E A;  2B4P A;  2ESB A;  4BJO A;  3GXG A;  2GCA A;  2JFF A;  1I9S A;  1C88 A;  3D1O A;  2X5O A;  4OHE A;  2I6P A;  2QCT A;  3QKQ A;  2F6F A;  2IMG A;  3AWG A;  2F6Z A;  1AAX A;  4ICZ A;  1PA9 A;  3B7O A;  4ZI4 A;  4GRY A;  2F46 A;  3ZM3 A;  4WOH A;  2QDP A;  2FJM A;  4YR8 B;  2UUP A;  5K24 A;  1NO6 A;  1WAX A;  3N0A A;  1NWE A;  2WTZ A;  4Z6B A;  2AM1 A;  4QAH A;  2P6X A;  1G4W R;  5BZZ A;  1QXK A;  1Q6M A;  1OHE A;  1Q6T A;  4RHG A;  3ZV2 A;  3V0F A;  2BIJ A;  3QCE A;  3D1H A;  2DXP A;  2I4G A;  3BLU A;  2VEU A;  4GE5 A;  5KAA A;  4HRF A;  1C86 A;  2CMB A;  5MMZ B;  1I57 A;  1OEV A; 
#chains in the Genus database with same CATH homology
 2HVL A;  5K9V A;  1ZC0 A;  3ZMQ A;  4MBB A;  2CJZ A;  4B04 A;  2CNH A;  2C46 A;  2F71 A;  4QBW A;  2F6W A;  3QCN A;  1XBO A;  4H34 A;  1ZCK A;  5LXQ B;  1ONZ A;  2CMA A;  1OET A;  1QZ0 A;  2I3R A;  1U24 A;  4IKC A;  4NX8 A;  1YZ4 A;  3RO1 A;  2F6T A;  5K23 A;  2HXP A;  5BX1 A;  2OZ5 A;  3D9C A;  5EHR A;  3V0D A;  2CM7 A;  2NT2 A;  2OUD A;  4NYH A;  3U96 A;  3ZM1 A;  5I6V A;  1PTU A;  4J51 A;  4HJP A;  4PYH A;  2J17 A;  3O4S A;  3V0H A;  3MOZ A;  2GWO A;  1LAR A;  1Q6S A;  3D42 A;  3ZMP A;  4WU2 A;  1X24 A;  1EEO A;  2AZR A;  1YWF A;  2I75 A;  1NNY A;  1PXH A;  4H1O A;  4R0S A;  5AWX A;  3S3H A;  1KAV A;  1JLN A;  1PTV A;  2PQ5 A;  1T48 A;  2VEV A;  2PBN A;  2CM2 A;  2B07 A;  5KA2 A;  3S4E A;  5KAD A;  1ZZW A;  3H2X A;  1EEN A;  3A5K A;  2H04 A;  5J8R A;  3F99 A;  3QCL A;  4DGP A;  1D5R A;  2Q47 A;  2BGE A;  4JMJ A;  3F81 A;  2CFV A;  3EAX A;  2ZMM A;  2CNG A;  3GXH A;  3PS5 A;  3RGO A;  3SR9 A;  2HNP A;  1C84 A;  1YFO A;  5HDE A;  4NND A;  2YDU A;  1PYN A;  3QCI A;  1YPT A;  3O3L A;  4ZN5 A;  4GFU A;  1OHC A;  1C85 A;  3QCK A;  2F70 A;  5KA0 A;  1A5Y A;  5KA8 A;  1NWL A;  2NTA A;  1Q1M A;  3V0I A;  1YTN A;  2B3O A;  1FQ1 A;  2QDC A;  4I8N A;  2E0T A;  1ONY A;  4DGX A;  1P15 A;  5BUG A;  2H4G A;  2I6I A;  3QCH A;  1T4J A;  4D3R A;  4RH5 A;  3CWE A;  5KA3 A;  1BZC A;  5KAC A;  1XRI A;  3QKP A;  4BPC A;  2G6Z A;  1SUG A;  3CM3 A;  1G7G A;  2NLK A;  1NL9 A;  1Q6J A;  3BM8 A;  5KAB A;  2SHP A;  4HJQ A;  2A8B A;  1OEM X;  2G59 A;  3F41 A;  2H4K A;  1ECV A;  2NZ6 A;  2QBR A;  2R0B A;  2HC1 A;  1YTS A;  3BLT A;  1LYV A;  2P4D A;  4RH9 A;  2J16 A;  3V0G A;  5KA1 A;  1R6H A;  3O5X A;  2BGD A;  4Y14 A;  1T49 A;  2MBC A;  3I80 A;  2A3K A;  2I6M A;  3F9B A;  2F6V A;  4OHD A;  2I1Y A;  3QCC A;  3D1Q A;  2B4S A;  3EMU A;  3S3E A;  2PA5 A;  1YGR A;  2ZN7 A;  2Y96 A;  1RPM A;  2I4E A;  3S4O A;  2B4U A;  3OLR A;  4JBC A;  4QBE A;  2FJN A;  1G7F A;  4D3P A;  1PA1 A;  1VHR A;  3S3K A;  1G1G A;  2PT0 A;  3QCB A;  4KI9 A;  5KA9 A;  3I7Z A;  2H03 A;  2CNF A;  1G4U S;  1G1F A;  3QCF A;  1WRM A;  2OC3 A;  3QCG A;  2I5X A;  2QBS A;  1FPR A;  4GFV A;  1PTY A;  5K22 A;  1U25 A;  5GTJ A;  2J16 B;  1ZCL A;  4OHI A;  2I6O A;  3EZZ A;  2HC2 A;  3O4T A;  5KA4 A;  5IBM A;  1JF7 A;  3MMJ A;  2PI7 A;  2Y2F A;  5K25 A;  4NWG A;  2JJD A;  3S3F A;  4RI4 A;  2BV5 A;  4RKK A;  2I3U A;  3QCM A;  4ERC A;  2HB1 A;  1KAK A;  2QDM A;  2QEP A;  1U26 A;  2OOQ A;  2CNE A;  4JMK A;  1J4X A;  2H02 A;  4RI5 A;  4R30 A;  2Q05 A;  4WTY A;  4QUN A;  3EU0 A;  1BZJ A;  2GJT A;  4R0T A;  1G1H A;  1OEU A;  4GE6 A;  2HY3 A;  4ZRT A;  1L8G A;  1Q6N A;  2GP0 A;  4GS0 A;  1C87 A;  3AWF A;  1PH0 A;  1GFY A;  2CM3 A;  2B49 A;  1PTT A;  3QCD A;  1XM2 A;  2FH7 A;  5IBS A;  2M3V A;  4WU3 A;  2NT7 A;  4NWF A;  4GWF A;  2BZL A;  3ZM2 A;  2CNI A;  3V0J A;  4KYR A;  2CM8 A;  3OMH A;  2NV5 A;  5K9W A;  2I42 A;  3BRH A;  4TVV A;  4YAA A;  2C7S A;  4S0G A;  3RGQ A;  2B4O A;  1RXD A;  3SME A;  5M43 A;  1MKP A;  2I6J A;  1WCH A;  4QUM A;  3D44 A;  4KYQ A;  1OHD A;  1Q6P A;  1FPZ A;  2CMC A;  5EHP A;  4GE2 A;  1M3G A;  4Y2E A;  5KA7 A;  2F6Y A;  2VEW A;  1GWZ A;  2QCJ A;  1I9T A;  3ZM0 A;  2VEX A;  1XXV A;  5BZX A;  1YN9 A;  2QBQ A;  3M4U A;  3O4U A;  2H4V A;  4AZ1 A;  1L8K A;  1V3A A;  2WGP A;  4QAP A;  3NME A;  2RF6 A;  2AHS A;  3LJ8 A;  4JNB A;  3AWE A;  1YTW A;  3EB1 A;  3QCJ A;  1OES A;  3A5J A;  3RZ2 A;  1C83 A;  3F9A A;  1NZ7 A;  2VEY A;  4PVG A;  2QBP A;  3I36 A;  4OHL A;  4RDD A;  1OEO X;  1LQF A;  1YGU A;  2HNQ A;  4OHH A;  1BZH A;  1XXP A;  4D3Q A;  2HCM A;  4GRZ A;  3MOW A;  2I4H A;  2PSZ A;  3V0E A;  2B4P A;  2ESB A;  4BJO A;  3GXG A;  1I9S A;  1C88 A;  3D1O A;  4OHE A;  2I6P A;  2QCT A;  3QKQ A;  2F6F A;  2IMG A;  3AWG A;  2F6Z A;  1AAX A;  4ICZ A;  1PA9 A;  3B7O A;  4ZI4 A;  4GRY A;  2F46 A;  3ZM3 A;  4WOH A;  2QDP A;  2FJM A;  4YR8 B;  5K24 A;  1NO6 A;  1WAX A;  3N0A A;  1NWE A;  4Z6B A;  4QAH A;  2P6X A;  1G4W R;  5BZZ A;  1QXK A;  1Q6M A;  1OHE A;  1Q6T A;  4RHG A;  3ZV2 A;  3V0F A;  2BIJ A;  3QCE A;  3D1H A;  2DXP A;  2I4G A;  3BLU A;  2VEU A;  4GE5 A;  5KAA A;  4HRF A;  1C86 A;  2CMB A;  5MMZ B;  1I57 A;  1OEV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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