1LQFA

Structure of ptp1b in complex with a peptidic bisphosphonate inhibitor
Total Genus 99

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
287
structure length
287
Chain Sequence
KLEFMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords protein-tyrosine phosphatase, non-receptor type 1
total genus 99
structure length 287
sequence length 287
chains with identical sequence B, C, D
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2002-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1lqfA00
2GWOA 4NYHA 4PYHA 3S3HA 3F81A 4WU2A 3F99A 2M3VA 5BUGA 4Y14A 5EHPA 3BLUA 3ZM0A 3V0JA 1LARA 1OEUA 1KAVA 1ONZA 2HC2A 3RO1A 1L8GA 1U24A 1RPMA 1YPTA 2VEYA 2NT2A 3S4EA 3AWGA 2B4PA 2A3KA 4AZ1A 4Z6BA 1C88A 4GFUA 4YR8B 5KADA 4GE6A 3QCDA 4R30A 2F6TA 3QCFA 3QCMA 3A5KA 3QKPA 3QCKA 5K23A 4GE5A 3U96A 1WCHA 2BZLA 4RI5A 2C46A 3RGOA 4BJOA 1NO6A 1BZHA 3D42A 1ZCLA 3EB1A 2MBCA 1OHEA 1Q6TA 3D9CA 4J51A 3I36A 4GE2A 4I8NA 5I6VA 2RF6A 4NNDA 1SUGA 3V0IA 2QBSA 1ONYA 2CNIA 2F6FA 5KA3A 1OESA 3V0GA 2F6WA 4RH5A 1PXHA 5KABA 1PA1A 3QKQA 2YDUA 5HDEA 1C86A 2PA5A 5KAAA 1G4WR 1R6HA 2I3UA 2QCJA 1OHDA 4PVGA 2H4GA 1G1HA 2I6IA 2I6OA 1AAXA 4WOHA 2HNPA 1L8KA 5KA0A 1U25A 1J4XA 4D3RA 2PQ5A 2VEVA 1P15A 2I1YA 3SMEA 2HNQA 5AWXA 3LJ8A 2I6PA 3D44A 1EEOA 2B3OA 2H4KA 2I6MA 1Q6JA 1YFOA 2CM7A 3V0FA 1WAXA 3QCJA 1PTYA 3ZMQA 4RI4A 3I7ZA 4DGXA 4QAHA 4ZI4A 5KA7A 2CNEA 3EAXA 1Q6MA 2DXPA 1D5RA 4H34A 2CFVA 4NX8A 1ECVA 2J16A 2C7SA 2F6YA 2I6JA 4JMKA 1NL9A 2QEPA 2VEXA 3QCGA 1GFYA 2QBQA 3GXGA 4GRYA 3A5JA 2NZ6A 3O4SA 2PT0A 1I57A 1Q6NA 4R0SA 2QDPA 3O5XA 1PH0A 3NMEA 2QCTA 2OOQA 2GP0A 3CWEA 5K25A 2I4GA 3MMJA 3RGQA 4B04A 2PSZA 3ZM2A 1M3GA 1OEOX 2NV5A 2H02A 4NWGA 4RDDA 5M43A 4QBWA 3I80A 2B4UA 1YGRA 2CMBA 1I9SA 2BV5A 2J16B 4D3QA 2CMCA 1G1GA 2ZMMA 1YN9A 4OHEA 2VEWA 1VHRA 3EMUA 2BGEA 5IBSA 5EHRA 2P4DA 3S3KA 4RKKA 4ZN5A 1C87A 4JBCA 2NTAA 4IKCA 2I5XA 5GTJA 1G1FA 5K24A 1PTUA 2CJZA 1Q6PA 2OZ5A 4HJPA 2QDMA 1PTVA 1MKPA 4Y2EA 1PYNA 2BIJA 2H03A 4OHIA 3MOZA 3M4UA 4RH9A 4H1OA 4D3PA 4GS0A 3V0EA 4TVVA 1QZ0A 2QBRA 5KA9A 2HY3A 2CNGA 3V0HA 1PA9A 1NZ7A 3D1OA 3RZ2A 2Q47A 3QCEA 4NWFA 1V3AA 1C85A 4ZRTA 3PS5A 2ESBA 3ZM3A 1I9TA 1GWZA 5LXQB 4HRFA 2WGPA 2P6XA 2QBPA 2I42A 1XXVA 2BGDA 1Q1MA 3BM8A 2SHPA 3QCHA 1OHCA 1YGUA 5KACA 2VEUA 1G7FA 4OHHA 1T48A 2CMAA 1OETA 1LYVA 5BZZA 4QUMA 2OUDA 2E0TA 4S0GA 3BRHA 3S4OA 1YZ4A 1YTWA 3SR9A 4ICZA 2I3RA 1OEMX 2A8BA 2B4SA 2I4HA 2FH7A 3V0DA 1OEVA 5KA1A 4GFVA 4WU3A 4QAPA 3B7OA 3ZMPA 2PI7A 3QCNA 1NNYA 3MOWA 4KYRA 1XM2A 2F6ZA 5K9WA 3N0AA 4OHLA 1G4US 4HJQA 4WTYA 4DGPA 5K9VA 2GJTA 2I4EA 1NWLA 1QXKA 3OMHA 1C83A 2FJMA 3BLTA 1FPRA 4GWFA 1X24A 2NT7A 2NLKA 2QDCA 1ZCKA 1FQ1A 2F6VA 3QCCA 1YWFA 3OLRA 3GXHA 1YTSA 1PTTA 2ZN7A 4JMJA 3AWFA 3D1QA 2Q05A 1ZZWA 3F9BA 4MBBA 3F9AA 2B07A 2HCMA 1XRIA 1RXDA 1EENA 1T4JA 2OC3A 2CM8A 1G7GA 1YTNA 4BPCA 3CM3A 3ZV2A 3AWEA 3H2XA 4QUNA 5BX1A 2HXPA 2G59A 5KA4A 4RHGA 3F41A 4YAAA 5BZXA 2HC1A 1WRMA 1FPZA 1JF7A 2HVLA 2IMGA 1LQFA 3D1HA 3O4UA 1BZJA 4ERCA 2CM2A 2J17A 4KYQA 5K22A 2I75A 5KA8A 4KI9A 3S3EA 2CNHA 2AZRA 1XXPA 5J8RA 1A5YA 3EZZA 2H04A 2JJDA 3S3FA 2PBNA 2FJNA 3O3LA 5KA2A 2F70A 1C84A 2G6ZA 4GRZA 2F46A 1ZC0A 3O4TA 5IBMA 4OHDA 3ZM1A 2CM3A 2B49A 1T49A 3EU0A 2Y2FA 3QCBA 1BZCA 1Q6SA 2R0BA 3QCIA 1XBOA 1JLNA 2CNFA 2HB1A 5MMZB 2AHSA 4QBEA 4R0TA 3QCLA 4JNBA 2Y96A 1KAKA 2B4OA 1U26A 2H4VA 2F71A 1NWEA
chains in the Genus database with same CATH superfamily
2GWOA 4NYHA 4PYHA 3S3HA 3F81A 4WU2A 1E8CA 3F99A 2M3VA 5BUGA 4Y14A 5EHPA 3BLUA 3ZM0A 3V0JA 1LARA 1OEUA 1KAVA 1ONZA 2HC2A 3RO1A 1L8GA 1J6UA 1U24A 1RPMA 1YPTA 2VEYA 2NT2A 3S4EA 3AWGA 2B4PA 2A3KA 4AZ1A 4Z6BA 1C88A 4GFUA 4YR8B 5KADA 4GE6A 3QCDA 4R30A 2F6TA 3QCFA 3QCMA 3A5KA 1O5ZA 3QKPA 3MVNA 3QCKA 5K23A 4GE5A 3U96A 1WCHA 2BZLA 4RI5A 2C46A 2GC5A 1JBVA 3RGOA 4BJOA 1NO6A 1BZHA 3D42A 3UAGA 1ZCLA 3EB1A 2MBCA 1OHEA 1Q6TA 3QCZA 3D9CA 4J51A 3I36A 4GE2A 4I8NA 5I6VA 2RF6A 4NNDA 4C13A 1SUGA 3V0IA 1GG4A 2QBSA 1ONYA 1UAGA 2CNIA 2F6FA 2GCAA 5KA3A 1OESA 3V0GA 2F6WA 4RH5A 1PXHA 5KABA 1PA1A 3QKQA 2YDUA 5HDEA 1C86A 2PA5A 2Y1OA 5KAAA 2QCJA 1G4WR 1R6HA 2I3UA 1GQYA 1OHDA 4PVGA 2H4GA 3N2AA 1G1HA 2I6IA 3PYZA 2I6OA 1AAXA 4WOHA 2HNPA 1EEHA 2WJPA 1L8KA 5KA0A 1U25A 1J4XA 2VORA 4D3RA 2PQ5A 2VEVA 1P15A 2I1YA 3SMEA 2HNQA 5AWXA 3LJ8A 2I6PA 3D44A 1EEOA 2B3OA 2H4KA 3ZM5A 2I6MA 1Q6JA 1YFOA 2CM7A 3V0FA 1WAXA 3QCJA 1PTYA 3ZMQA 4RI4A 3I7ZA 4DGXA 4QAHA 4ZI4A 5KA7A 2CNEA 2F00A 3EAXA 1Q6MA 2DXPA 1D5RA 4H34A 2CFVA 4NX8A 1ECVA 2J16A 2C7SA 2F6YA 1P3DA 2I6JA 4JMKA 1NL9A 2QEPA 4C12A 2JFGA 2VEXA 2X5OA 3QCGA 1GFYA 2QBQA 3GXGA 4GRYA 3A5JA 2NZ6A 3O4SA 2PT0A 1I57A 1Q6NA 4R0SA 2QDPA 4BUCA 3O5XA 1PH0A 3NMEA 3LK7A 2QCTA 2OOQA 2GP0A 3CWEA 5K25A 2I4GA 1FGSA 3MMJA 3RGQA 4B04A 2PSZA 3ZM2A 1M3GA 1OEOX 2NV5A 2H02A 4NWGA 4RDDA 5M43A 4QBWA 3I80A 2B4UA 1YGRA 2CMBA 1I9SA 2BV5A 2J16B 4D3QA 2CMCA 1G1GA 2ZMMA 1YN9A 4OHEA 2Y67A 2VEWA 1VHRA 3EMUA 2BGEA 5IBSA 5EHRA 2P4DA 3S3KA 4RKKA 4ZN5A 1C87A 2XPCA 4JBCA 2NTAA 4IKCA 2I5XA 5GTJA 1G1FA 5K24A 1PTUA 2CJZA 1Q6PA 2OZ5A 4HJPA 2QDMA 1PTVA 1MKPA 4Y2EA 1PYNA 2BIJA 2H03A 4OHIA 3MOZA 3M4UA 4RH9A 4HV4A 4H1OA 4D3PA 2GC6A 4GS0A 3V0EA 2VOSA 4TVVA 4BUBA 1QZ0A 2JFFA 2QBRA 4ZIYA 5KA9A 2AM1A 2HY3A 2CNGA 3V0HA 1PA9A 1NZ7A 3D1OA 3RZ2A 2Q47A 3QCEA 4NWFA 1E0DA 1V3AA 1C85A 4ZRTA 3PS5A 2ESBA 2Y66A 2UUOA 3ZM3A 1I9TA 1GWZA 4UAGA 5LXQB 4HRFA 2WGPA 2P6XA 2QBPA 2I42A 1XXVA 2VTDA 2BGDA 1Q1MA 3BM8A 2SHPA 3QCHA 1OHCA 1YGUA 4QF5A 2VEUA 5KACA 1G7FA 4OHHA 1T48A 2CMAA 1OETA 1LYVA 5BZZA 4QUMA 2OUDA 2E0TA 2Y68A 2XJAA 4S0GA 3BRHA 3S4OA 1YZ4A 1YTWA 3SR9A 4ICZA 2I3RA 5A5EA 1GQQA 1OEMX 2A8BA 2B4SA 2I4HA 2FH7A 3V0DA 1OEVA 5KA1A 4GFVA 4WU3A 4QAPA 3B7OA 3ZMPA 2PI7A 2UUPA 2GCBA 3QCNA 1NNYA 3MOWA 4KYRA 1XM2A 2F6ZA 1W7KA 5K9WA 3N0AA 4OHLA 1G4US 4HJQA 4WTYA 4DGPA 5K9VA 2GJTA 2I4EA 2UAGA 1NWLA 1QXKA 3OMHA 1C83A 2FJMA 3BLTA 1FPRA 4GWFA 1X24A 2NT7A 2NLKA 2QDCA 1ZCKA 1FQ1A 2F6VA 3QCCA 1YWFA 3OLRA 3GXHA 1YTSA 1PTTA 2ZN7A 4JMJA 3AWFA 3D1QA 2Q05A 1ZZWA 3F9BA 4CVMA 3ZL8A 4MBBA 3F9AA 2B07A 1P31A 2HCMA 1XRIA 1RXDA 1EENA 1T4JA 2OC3A 2CM8A 1G7GA 1YTNA 4BPCA 3CM3A 3ZV2A 3AWEA 3H2XA 4QUNA 3ZM6A 5BX1A 2HXPA 2G59A 4CVKA 2VTEA 5KA4A 4RHGA 1JBWA 1W78A 3F41A 4YAAA 5BZXA 2HC1A 1WRMA 4CVLA 1FPZA 1JF7A 2HVLA 2IMGA 1LQFA 3D1HA 3O4UA 1BZJA 4ERCA 2CM2A 2J17A 4KYQA 5K22A 2I75A 5KA8A 4KI9A 3S3EA 2CNHA 2AZRA 1XXPA 5J8RA 1A5YA 3EZZA 4QDIA 2H04A 2JJDA 3S3FA 2PBNA 2FJNA 3O3LA 5KA2A 3NRSA 3HN7A 2F70A 1C84A 2G6ZA 4GRZA 2F46A 1ZC0A 3O4TA 5IBMA 4OHDA 3ZM1A 2CM3A 2B49A 1T49A 3EU0A 2Y2FA 3QCBA 1BZCA 1Q6SA 2R0BA 3QCIA 1XBOA 1JLNA 2CNFA 2HB1A 5MMZB 2AHSA 4QBEA 4R0TA 5A5FA 3QCLA 4JNBA 2WTZA 2Y96A 1KAKA 2B4OA 2AM2A 1U26A 2H4VA 2F71A 1NWEA 2JFHA
chains in the Genus database with same CATH topology
2GWOA 4NYHA 4PYHA 3S3HA 3F81A 4WU2A 3F99A 2M3VA 5BUGA 4Y14A 5EHPA 3BLUA 3ZM0A 3V0JA 1LARA 1OEUA 1KAVA 1ONZA 2HC2A 3RO1A 1L8GA 1U24A 1RPMA 1YPTA 2VEYA 2NT2A 3S4EA 3AWGA 2B4PA 2A3KA 4AZ1A 4Z6BA 1C88A 4GFUA 4YR8B 5KADA 4GE6A 3QCDA 4R30A 2F6TA 3QCFA 3QCMA 3A5KA 3QKPA 3QCKA 5K23A 4GE5A 3U96A 1WCHA 2BZLA 4RI5A 2C46A 3RGOA 4BJOA 1NO6A 1BZHA 3D42A 1ZCLA 3EB1A 2MBCA 1OHEA 1Q6TA 3D9CA 4J51A 3I36A 4GE2A 4I8NA 5I6VA 2RF6A 4NNDA 1SUGA 3V0IA 2QBSA 1ONYA 2CNIA 2F6FA 5KA3A 1OESA 3V0GA 2F6WA 4RH5A 1PXHA 5KABA 1PA1A 3QKQA 2YDUA 5HDEA 1C86A 2PA5A 5KAAA 1G4WR 1R6HA 2I3UA 2QCJA 1OHDA 4PVGA 2H4GA 1G1HA 2I6IA 2I6OA 1AAXA 4WOHA 2HNPA 1L8KA 5KA0A 1U25A 1J4XA 4D3RA 2PQ5A 2VEVA 1P15A 2I1YA 3SMEA 2HNQA 5AWXA 3LJ8A 2I6PA 3D44A 1EEOA 2B3OA 2H4KA 2I6MA 1Q6JA 1YFOA 2CM7A 3V0FA 1WAXA 3QCJA 1PTYA 3ZMQA 4RI4A 3I7ZA 4DGXA 4QAHA 4ZI4A 5KA7A 2CNEA 3EAXA 1Q6MA 2DXPA 1D5RA 4H34A 2CFVA 4NX8A 1ECVA 2J16A 2C7SA 2F6YA 2I6JA 4JMKA 1NL9A 2QEPA 2VEXA 3QCGA 1GFYA 2QBQA 3GXGA 4GRYA 3A5JA 2NZ6A 3O4SA 2PT0A 1I57A 1Q6NA 4R0SA 2QDPA 3O5XA 1PH0A 3NMEA 2QCTA 2OOQA 2GP0A 3CWEA 5K25A 2I4GA 3MMJA 3RGQA 4B04A 2PSZA 3ZM2A 1M3GA 1OEOX 2NV5A 2H02A 4NWGA 4RDDA 5M43A 4QBWA 3I80A 2B4UA 1YGRA 2CMBA 1I9SA 2BV5A 2J16B 4D3QA 2CMCA 1G1GA 2ZMMA 1YN9A 4OHEA 2VEWA 1VHRA 3EMUA 2BGEA 5IBSA 5EHRA 2P4DA 3S3KA 4RKKA 4ZN5A 1C87A 4JBCA 2NTAA 4IKCA 2I5XA 5GTJA 1G1FA 5K24A 1PTUA 2CJZA 1Q6PA 2OZ5A 4HJPA 2QDMA 1PTVA 1MKPA 4Y2EA 1PYNA 2BIJA 2H03A 4OHIA 3MOZA 3M4UA 4RH9A 4H1OA 4D3PA 4GS0A 3V0EA 4TVVA 1QZ0A 2QBRA 5KA9A 2HY3A 2CNGA 3V0HA 1PA9A 1NZ7A 3D1OA 3RZ2A 2Q47A 3QCEA 4NWFA 1V3AA 1C85A 4ZRTA 3PS5A 2ESBA 3ZM3A 1I9TA 1GWZA 5LXQB 4HRFA 2WGPA 2P6XA 2QBPA 2I42A 1XXVA 2BGDA 1Q1MA 3BM8A 2SHPA 3QCHA 1OHCA 1YGUA 5KACA 2VEUA 1G7FA 4OHHA 1T48A 2CMAA 1OETA 1LYVA 5BZZA 4QUMA 2OUDA 2E0TA 4S0GA 3BRHA 3S4OA 1YZ4A 1YTWA 3SR9A 4ICZA 2I3RA 1OEMX 2A8BA 2B4SA 2I4HA 2FH7A 3V0DA 1OEVA 5KA1A 4GFVA 4WU3A 4QAPA 3B7OA 3ZMPA 2PI7A 3QCNA 1NNYA 3MOWA 4KYRA 1XM2A 2F6ZA 5K9WA 3N0AA 4OHLA 1G4US 4HJQA 4WTYA 4DGPA 5K9VA 2GJTA 2I4EA 1NWLA 1QXKA 3OMHA 1C83A 2FJMA 3BLTA 1FPRA 4GWFA 1X24A 2NT7A 2NLKA 2QDCA 1ZCKA 1FQ1A 2F6VA 3QCCA 1YWFA 3OLRA 3GXHA 1YTSA 1PTTA 2ZN7A 4JMJA 3AWFA 3D1QA 2Q05A 1ZZWA 3F9BA 4MBBA 3F9AA 2B07A 2HCMA 1XRIA 1RXDA 1EENA 1T4JA 2OC3A 2CM8A 1G7GA 1YTNA 4BPCA 3CM3A 3ZV2A 3AWEA 3H2XA 4QUNA 5BX1A 2HXPA 2G59A 5KA4A 4RHGA 3F41A 4YAAA 5BZXA 2HC1A 1WRMA 1FPZA 1JF7A 2HVLA 2IMGA 1LQFA 3D1HA 3O4UA 1BZJA 4ERCA 2CM2A 2J17A 4KYQA 5K22A 2I75A 5KA8A 4KI9A 3S3EA 2CNHA 2AZRA 1XXPA 5J8RA 1A5YA 3EZZA 2H04A 2JJDA 3S3FA 2PBNA 2FJNA 3O3LA 5KA2A 2F70A 1C84A 2G6ZA 4GRZA 2F46A 1ZC0A 3O4TA 5IBMA 4OHDA 3ZM1A 2CM3A 2B49A 1T49A 3EU0A 2Y2FA 3QCBA 1BZCA 1Q6SA 2R0BA 3QCIA 1XBOA 1JLNA 2CNFA 2HB1A 5MMZB 2AHSA 4QBEA 4R0TA 3QCLA 4JNBA 2Y96A 1KAKA 2B4OA 1U26A 2H4VA 2F71A 1NWEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GWO A;  4NYH A;  4PYH A;  3S3H A;  3F81 A;  4WU2 A;  3F99 A;  2M3V A;  5BUG A;  4Y14 A;  5EHP A;  3BLU A;  3ZM0 A;  3V0J A;  1LAR A;  1OEU A;  1KAV A;  1ONZ A;  2HC2 A;  3RO1 A;  1L8G A;  1U24 A;  1RPM A;  1YPT A;  2VEY A;  2NT2 A;  3S4E A;  3AWG A;  2B4P A;  2A3K A;  4AZ1 A;  4Z6B A;  1C88 A;  4GFU A;  4YR8 B;  5KAD A;  4GE6 A;  3QCD A;  4R30 A;  2F6T A;  3QCF A;  3QCM A;  3A5K A;  3QKP A;  3QCK A;  5K23 A;  4GE5 A;  3U96 A;  1WCH A;  2BZL A;  4RI5 A;  2C46 A;  3RGO A;  4BJO A;  1NO6 A;  1BZH A;  3D42 A;  1ZCL A;  3EB1 A;  2MBC A;  1OHE A;  1Q6T A;  3D9C A;  4J51 A;  3I36 A;  4GE2 A;  4I8N A;  5I6V A;  2RF6 A;  4NND A;  1SUG A;  3V0I A;  2QBS A;  1ONY A;  2CNI A;  2F6F A;  5KA3 A;  1OES A;  3V0G A;  2F6W A;  4RH5 A;  1PXH A;  5KAB A;  1PA1 A;  3QKQ A;  2YDU A;  5HDE A;  1C86 A;  2PA5 A;  5KAA A;  1G4W R;  1R6H A;  2I3U A;  2QCJ A;  1OHD A;  4PVG A;  2H4G A;  1G1H A;  2I6I A;  2I6O A;  1AAX A;  4WOH A;  2HNP A;  1L8K A;  5KA0 A;  1U25 A;  1J4X A;  4D3R A;  2PQ5 A;  2VEV A;  1P15 A;  2I1Y A;  3SME A;  2HNQ A;  5AWX A;  3LJ8 A;  2I6P A;  3D44 A;  1EEO A;  2B3O A;  2H4K A;  2I6M A;  1Q6J A;  1YFO A;  2CM7 A;  3V0F A;  1WAX A;  3QCJ A;  1PTY A;  3ZMQ A;  4RI4 A;  3I7Z A;  4DGX A;  4QAH A;  4ZI4 A;  5KA7 A;  2CNE A;  3EAX A;  1Q6M A;  2DXP A;  1D5R A;  4H34 A;  2CFV A;  4NX8 A;  1ECV A;  2J16 A;  2C7S A;  2F6Y A;  2I6J A;  4JMK A;  1NL9 A;  2QEP A;  2VEX A;  3QCG A;  1GFY A;  2QBQ A;  3GXG A;  4GRY A;  3A5J A;  2NZ6 A;  3O4S A;  2PT0 A;  1I57 A;  1Q6N A;  4R0S A;  2QDP A;  3O5X A;  1PH0 A;  3NME A;  2QCT A;  2OOQ A;  2GP0 A;  3CWE A;  5K25 A;  2I4G A;  3MMJ A;  3RGQ A;  4B04 A;  2PSZ A;  3ZM2 A;  1M3G A;  1OEO X;  2NV5 A;  2H02 A;  4NWG A;  4RDD A;  5M43 A;  4QBW A;  3I80 A;  2B4U A;  1YGR A;  2CMB A;  1I9S A;  2BV5 A;  2J16 B;  4D3Q A;  2CMC A;  1G1G A;  2ZMM A;  1YN9 A;  4OHE A;  2VEW A;  1VHR A;  3EMU A;  2BGE A;  5IBS A;  5EHR A;  2P4D A;  3S3K A;  4RKK A;  4ZN5 A;  1C87 A;  4JBC A;  2NTA A;  4IKC A;  2I5X A;  5GTJ A;  1G1F A;  5K24 A;  1PTU A;  2CJZ A;  1Q6P A;  2OZ5 A;  4HJP A;  2QDM A;  1PTV A;  1MKP A;  4Y2E A;  1PYN A;  2BIJ A;  2H03 A;  4OHI A;  3MOZ A;  3M4U A;  4RH9 A;  4H1O A;  4D3P A;  4GS0 A;  3V0E A;  4TVV A;  1QZ0 A;  2QBR A;  5KA9 A;  2HY3 A;  2CNG A;  3V0H A;  1PA9 A;  1NZ7 A;  3D1O A;  3RZ2 A;  2Q47 A;  3QCE A;  4NWF A;  1V3A A;  1C85 A;  4ZRT A;  3PS5 A;  2ESB A;  3ZM3 A;  1I9T A;  1GWZ A;  5LXQ B;  4HRF A;  2WGP A;  2P6X A;  2QBP A;  2I42 A;  1XXV A;  2BGD A;  1Q1M A;  3BM8 A;  2SHP A;  3QCH A;  1OHC A;  1YGU A;  5KAC A;  2VEU A;  1G7F A;  4OHH A;  1T48 A;  2CMA A;  1OET A;  1LYV A;  5BZZ A;  4QUM A;  2OUD A;  2E0T A;  4S0G A;  3BRH A;  3S4O A;  1YZ4 A;  1YTW A;  3SR9 A;  4ICZ A;  2I3R A;  1OEM X;  2A8B A;  2B4S A;  2I4H A;  2FH7 A;  3V0D A;  1OEV A;  5KA1 A;  4GFV A;  4WU3 A;  4QAP A;  3B7O A;  3ZMP A;  2PI7 A;  3QCN A;  1NNY A;  3MOW A;  4KYR A;  1XM2 A;  2F6Z A;  5K9W A;  3N0A A;  4OHL A;  1G4U S;  4HJQ A;  4WTY A;  4DGP A;  5K9V A;  2GJT A;  2I4E A;  1NWL A;  1QXK A;  3OMH A;  1C83 A;  2FJM A;  3BLT A;  1FPR A;  4GWF A;  1X24 A;  2NT7 A;  2NLK A;  2QDC A;  1ZCK A;  1FQ1 A;  2F6V A;  3QCC A;  1YWF A;  3OLR A;  3GXH A;  1YTS A;  1PTT A;  2ZN7 A;  4JMJ A;  3AWF A;  3D1Q A;  2Q05 A;  1ZZW A;  3F9B A;  4MBB A;  3F9A A;  2B07 A;  2HCM A;  1XRI A;  1RXD A;  1EEN A;  1T4J A;  2OC3 A;  2CM8 A;  1G7G A;  1YTN A;  4BPC A;  3CM3 A;  3ZV2 A;  3AWE A;  3H2X A;  4QUN A;  5BX1 A;  2HXP A;  2G59 A;  5KA4 A;  4RHG A;  3F41 A;  4YAA A;  5BZX A;  2HC1 A;  1WRM A;  1FPZ A;  1JF7 A;  2HVL A;  2IMG A;  1LQF A;  3D1H A;  3O4U A;  1BZJ A;  4ERC A;  2CM2 A;  2J17 A;  4KYQ A;  5K22 A;  2I75 A;  5KA8 A;  4KI9 A;  3S3E A;  2CNH A;  2AZR A;  1XXP A;  5J8R A;  1A5Y A;  3EZZ A;  2H04 A;  2JJD A;  3S3F A;  2PBN A;  2FJN A;  3O3L A;  5KA2 A;  2F70 A;  1C84 A;  2G6Z A;  4GRZ A;  2F46 A;  1ZC0 A;  3O4T A;  5IBM A;  4OHD A;  3ZM1 A;  2CM3 A;  2B49 A;  1T49 A;  3EU0 A;  2Y2F A;  3QCB A;  1BZC A;  1Q6S A;  2R0B A;  3QCI A;  1XBO A;  1JLN A;  2CNF A;  2HB1 A;  5MMZ B;  2AHS A;  4QBE A;  4R0T A;  3QCL A;  4JNB A;  2Y96 A;  1KAK A;  2B4O A;  1U26 A;  2H4V A;  2F71 A;  1NWE A; 
#chains in the Genus database with same CATH topology
 2GWO A;  4NYH A;  4PYH A;  3S3H A;  3F81 A;  4WU2 A;  1E8C A;  3F99 A;  2M3V A;  5BUG A;  4Y14 A;  5EHP A;  3BLU A;  3ZM0 A;  3V0J A;  1LAR A;  1OEU A;  1KAV A;  1ONZ A;  2HC2 A;  3RO1 A;  1L8G A;  1J6U A;  1U24 A;  1RPM A;  1YPT A;  2VEY A;  2NT2 A;  3S4E A;  3AWG A;  2B4P A;  2A3K A;  4AZ1 A;  4Z6B A;  1C88 A;  4GFU A;  4YR8 B;  5KAD A;  4GE6 A;  3QCD A;  4R30 A;  2F6T A;  3QCF A;  3QCM A;  3A5K A;  1O5Z A;  3QKP A;  3MVN A;  3QCK A;  5K23 A;  4GE5 A;  3U96 A;  1WCH A;  2BZL A;  4RI5 A;  2C46 A;  2GC5 A;  1JBV A;  3RGO A;  4BJO A;  1NO6 A;  1BZH A;  3D42 A;  3UAG A;  1ZCL A;  3EB1 A;  2MBC A;  1OHE A;  1Q6T A;  3QCZ A;  3D9C A;  4J51 A;  3I36 A;  4GE2 A;  4I8N A;  5I6V A;  2RF6 A;  4NND A;  4C13 A;  1SUG A;  3V0I A;  1GG4 A;  2QBS A;  1ONY A;  1UAG A;  2CNI A;  2F6F A;  2GCA A;  5KA3 A;  1OES A;  3V0G A;  2F6W A;  4RH5 A;  1PXH A;  5KAB A;  1PA1 A;  3QKQ A;  2YDU A;  5HDE A;  1C86 A;  2PA5 A;  2Y1O A;  5KAA A;  2QCJ A;  1G4W R;  1R6H A;  2I3U A;  1GQY A;  1OHD A;  4PVG A;  2H4G A;  3N2A A;  1G1H A;  2I6I A;  3PYZ A;  2I6O A;  1AAX A;  4WOH A;  2HNP A;  1EEH A;  2WJP A;  1L8K A;  5KA0 A;  1U25 A;  1J4X A;  2VOR A;  4D3R A;  2PQ5 A;  2VEV A;  1P15 A;  2I1Y A;  3SME A;  2HNQ A;  5AWX A;  3LJ8 A;  2I6P A;  3D44 A;  1EEO A;  2B3O A;  2H4K A;  3ZM5 A;  2I6M A;  1Q6J A;  1YFO A;  2CM7 A;  3V0F A;  1WAX A;  3QCJ A;  1PTY A;  3ZMQ A;  4RI4 A;  3I7Z A;  4DGX A;  4QAH A;  4ZI4 A;  5KA7 A;  2CNE A;  2F00 A;  3EAX A;  1Q6M A;  2DXP A;  1D5R A;  4H34 A;  2CFV A;  4NX8 A;  1ECV A;  2J16 A;  2C7S A;  2F6Y A;  1P3D A;  2I6J A;  4JMK A;  1NL9 A;  2QEP A;  4C12 A;  2JFG A;  2VEX A;  2X5O A;  3QCG A;  1GFY A;  2QBQ A;  3GXG A;  4GRY A;  3A5J A;  2NZ6 A;  3O4S A;  2PT0 A;  1I57 A;  1Q6N A;  4R0S A;  2QDP A;  4BUC A;  3O5X A;  1PH0 A;  3NME A;  3LK7 A;  2QCT A;  2OOQ A;  2GP0 A;  3CWE A;  5K25 A;  2I4G A;  1FGS A;  3MMJ A;  3RGQ A;  4B04 A;  2PSZ A;  3ZM2 A;  1M3G A;  1OEO X;  2NV5 A;  2H02 A;  4NWG A;  4RDD A;  5M43 A;  4QBW A;  3I80 A;  2B4U A;  1YGR A;  2CMB A;  1I9S A;  2BV5 A;  2J16 B;  4D3Q A;  2CMC A;  1G1G A;  2ZMM A;  1YN9 A;  4OHE A;  2Y67 A;  2VEW A;  1VHR A;  3EMU A;  2BGE A;  5IBS A;  5EHR A;  2P4D A;  3S3K A;  4RKK A;  4ZN5 A;  1C87 A;  2XPC A;  4JBC A;  2NTA A;  4IKC A;  2I5X A;  5GTJ A;  1G1F A;  5K24 A;  1PTU A;  2CJZ A;  1Q6P A;  2OZ5 A;  4HJP A;  2QDM A;  1PTV A;  1MKP A;  4Y2E A;  1PYN A;  2BIJ A;  2H03 A;  4OHI A;  3MOZ A;  3M4U A;  4RH9 A;  4HV4 A;  4H1O A;  4D3P A;  2GC6 A;  4GS0 A;  3V0E A;  2VOS A;  4TVV A;  4BUB A;  1QZ0 A;  2JFF A;  2QBR A;  4ZIY A;  5KA9 A;  2AM1 A;  2HY3 A;  2CNG A;  3V0H A;  1PA9 A;  1NZ7 A;  3D1O A;  3RZ2 A;  2Q47 A;  3QCE A;  4NWF A;  1E0D A;  1V3A A;  1C85 A;  4ZRT A;  3PS5 A;  2ESB A;  2Y66 A;  2UUO A;  3ZM3 A;  1I9T A;  1GWZ A;  4UAG A;  5LXQ B;  4HRF A;  2WGP A;  2P6X A;  2QBP A;  2I42 A;  1XXV A;  2VTD A;  2BGD A;  1Q1M A;  3BM8 A;  2SHP A;  3QCH A;  1OHC A;  1YGU A;  4QF5 A;  2VEU A;  5KAC A;  1G7F A;  4OHH A;  1T48 A;  2CMA A;  1OET A;  1LYV A;  5BZZ A;  4QUM A;  2OUD A;  2E0T A;  2Y68 A;  2XJA A;  4S0G A;  3BRH A;  3S4O A;  1YZ4 A;  1YTW A;  3SR9 A;  4ICZ A;  2I3R A;  5A5E A;  1GQQ A;  1OEM X;  2A8B A;  2B4S A;  2I4H A;  2FH7 A;  3V0D A;  1OEV A;  5KA1 A;  4GFV A;  4WU3 A;  4QAP A;  3B7O A;  3ZMP A;  2PI7 A;  2UUP A;  2GCB A;  3QCN A;  1NNY A;  3MOW A;  4KYR A;  1XM2 A;  2F6Z A;  1W7K A;  5K9W A;  3N0A A;  4OHL A;  1G4U S;  4HJQ A;  4WTY A;  4DGP A;  5K9V A;  2GJT A;  2I4E A;  2UAG A;  1NWL A;  1QXK A;  3OMH A;  1C83 A;  2FJM A;  3BLT A;  1FPR A;  4GWF A;  1X24 A;  2NT7 A;  2NLK A;  2QDC A;  1ZCK A;  1FQ1 A;  2F6V A;  3QCC A;  1YWF A;  3OLR A;  3GXH A;  1YTS A;  1PTT A;  2ZN7 A;  4JMJ A;  3AWF A;  3D1Q A;  2Q05 A;  1ZZW A;  3F9B A;  4CVM A;  3ZL8 A;  4MBB A;  3F9A A;  2B07 A;  1P31 A;  2HCM A;  1XRI A;  1RXD A;  1EEN A;  1T4J A;  2OC3 A;  2CM8 A;  1G7G A;  1YTN A;  4BPC A;  3CM3 A;  3ZV2 A;  3AWE A;  3H2X A;  4QUN A;  3ZM6 A;  5BX1 A;  2HXP A;  2G59 A;  4CVK A;  2VTE A;  5KA4 A;  4RHG A;  1JBW A;  1W78 A;  3F41 A;  4YAA A;  5BZX A;  2HC1 A;  1WRM A;  4CVL A;  1FPZ A;  1JF7 A;  2HVL A;  2IMG A;  1LQF A;  3D1H A;  3O4U A;  1BZJ A;  4ERC A;  2CM2 A;  2J17 A;  4KYQ A;  5K22 A;  2I75 A;  5KA8 A;  4KI9 A;  3S3E A;  2CNH A;  2AZR A;  1XXP A;  5J8R A;  1A5Y A;  3EZZ A;  4QDI A;  2H04 A;  2JJD A;  3S3F A;  2PBN A;  2FJN A;  3O3L A;  5KA2 A;  3NRS A;  3HN7 A;  2F70 A;  1C84 A;  2G6Z A;  4GRZ A;  2F46 A;  1ZC0 A;  3O4T A;  5IBM A;  4OHD A;  3ZM1 A;  2CM3 A;  2B49 A;  1T49 A;  3EU0 A;  2Y2F A;  3QCB A;  1BZC A;  1Q6S A;  2R0B A;  3QCI A;  1XBO A;  1JLN A;  2CNF A;  2HB1 A;  5MMZ B;  2AHS A;  4QBE A;  4R0T A;  5A5F A;  3QCL A;  4JNB A;  2WTZ A;  2Y96 A;  1KAK A;  2B4O A;  2AM2 A;  1U26 A;  2H4V A;  2F71 A;  1NWE A;  2JFH A; 
#chains in the Genus database with same CATH homology
 2GWO A;  4NYH A;  4PYH A;  3S3H A;  3F81 A;  4WU2 A;  3F99 A;  2M3V A;  5BUG A;  4Y14 A;  5EHP A;  3BLU A;  3ZM0 A;  3V0J A;  1LAR A;  1OEU A;  1KAV A;  1ONZ A;  2HC2 A;  3RO1 A;  1L8G A;  1U24 A;  1RPM A;  1YPT A;  2VEY A;  2NT2 A;  3S4E A;  3AWG A;  2B4P A;  2A3K A;  4AZ1 A;  4Z6B A;  1C88 A;  4GFU A;  4YR8 B;  5KAD A;  4GE6 A;  3QCD A;  4R30 A;  2F6T A;  3QCF A;  3QCM A;  3A5K A;  3QKP A;  3QCK A;  5K23 A;  4GE5 A;  3U96 A;  1WCH A;  2BZL A;  4RI5 A;  2C46 A;  3RGO A;  4BJO A;  1NO6 A;  1BZH A;  3D42 A;  1ZCL A;  3EB1 A;  2MBC A;  1OHE A;  1Q6T A;  3D9C A;  4J51 A;  3I36 A;  4GE2 A;  4I8N A;  5I6V A;  2RF6 A;  4NND A;  1SUG A;  3V0I A;  2QBS A;  1ONY A;  2CNI A;  2F6F A;  5KA3 A;  1OES A;  3V0G A;  2F6W A;  4RH5 A;  1PXH A;  5KAB A;  1PA1 A;  3QKQ A;  2YDU A;  5HDE A;  1C86 A;  2PA5 A;  5KAA A;  1G4W R;  1R6H A;  2I3U A;  2QCJ A;  1OHD A;  4PVG A;  2H4G A;  1G1H A;  2I6I A;  2I6O A;  1AAX A;  4WOH A;  2HNP A;  1L8K A;  5KA0 A;  1U25 A;  1J4X A;  4D3R A;  2PQ5 A;  2VEV A;  1P15 A;  2I1Y A;  3SME A;  2HNQ A;  5AWX A;  3LJ8 A;  2I6P A;  3D44 A;  1EEO A;  2B3O A;  2H4K A;  2I6M A;  1Q6J A;  1YFO A;  2CM7 A;  3V0F A;  1WAX A;  3QCJ A;  1PTY A;  3ZMQ A;  4RI4 A;  3I7Z A;  4DGX A;  4QAH A;  4ZI4 A;  5KA7 A;  2CNE A;  3EAX A;  1Q6M A;  2DXP A;  1D5R A;  4H34 A;  2CFV A;  4NX8 A;  1ECV A;  2J16 A;  2C7S A;  2F6Y A;  2I6J A;  4JMK A;  1NL9 A;  2QEP A;  2VEX A;  3QCG A;  1GFY A;  2QBQ A;  3GXG A;  4GRY A;  3A5J A;  2NZ6 A;  3O4S A;  2PT0 A;  1I57 A;  1Q6N A;  4R0S A;  2QDP A;  3O5X A;  1PH0 A;  3NME A;  2QCT A;  2OOQ A;  2GP0 A;  3CWE A;  5K25 A;  2I4G A;  3MMJ A;  3RGQ A;  4B04 A;  2PSZ A;  3ZM2 A;  1M3G A;  1OEO X;  2NV5 A;  2H02 A;  4NWG A;  4RDD A;  5M43 A;  4QBW A;  3I80 A;  2B4U A;  1YGR A;  2CMB A;  1I9S A;  2BV5 A;  2J16 B;  4D3Q A;  2CMC A;  1G1G A;  2ZMM A;  1YN9 A;  4OHE A;  2VEW A;  1VHR A;  3EMU A;  2BGE A;  5IBS A;  5EHR A;  2P4D A;  3S3K A;  4RKK A;  4ZN5 A;  1C87 A;  4JBC A;  2NTA A;  4IKC A;  2I5X A;  5GTJ A;  1G1F A;  5K24 A;  1PTU A;  2CJZ A;  1Q6P A;  2OZ5 A;  4HJP A;  2QDM A;  1PTV A;  1MKP A;  4Y2E A;  1PYN A;  2BIJ A;  2H03 A;  4OHI A;  3MOZ A;  3M4U A;  4RH9 A;  4H1O A;  4D3P A;  4GS0 A;  3V0E A;  4TVV A;  1QZ0 A;  2QBR A;  5KA9 A;  2HY3 A;  2CNG A;  3V0H A;  1PA9 A;  1NZ7 A;  3D1O A;  3RZ2 A;  2Q47 A;  3QCE A;  4NWF A;  1V3A A;  1C85 A;  4ZRT A;  3PS5 A;  2ESB A;  3ZM3 A;  1I9T A;  1GWZ A;  5LXQ B;  4HRF A;  2WGP A;  2P6X A;  2QBP A;  2I42 A;  1XXV A;  2BGD A;  1Q1M A;  3BM8 A;  2SHP A;  3QCH A;  1OHC A;  1YGU A;  5KAC A;  2VEU A;  1G7F A;  4OHH A;  1T48 A;  2CMA A;  1OET A;  1LYV A;  5BZZ A;  4QUM A;  2OUD A;  2E0T A;  4S0G A;  3BRH A;  3S4O A;  1YZ4 A;  1YTW A;  3SR9 A;  4ICZ A;  2I3R A;  1OEM X;  2A8B A;  2B4S A;  2I4H A;  2FH7 A;  3V0D A;  1OEV A;  5KA1 A;  4GFV A;  4WU3 A;  4QAP A;  3B7O A;  3ZMP A;  2PI7 A;  3QCN A;  1NNY A;  3MOW A;  4KYR A;  1XM2 A;  2F6Z A;  5K9W A;  3N0A A;  4OHL A;  1G4U S;  4HJQ A;  4WTY A;  4DGP A;  5K9V A;  2GJT A;  2I4E A;  1NWL A;  1QXK A;  3OMH A;  1C83 A;  2FJM A;  3BLT A;  1FPR A;  4GWF A;  1X24 A;  2NT7 A;  2NLK A;  2QDC A;  1ZCK A;  1FQ1 A;  2F6V A;  3QCC A;  1YWF A;  3OLR A;  3GXH A;  1YTS A;  1PTT A;  2ZN7 A;  4JMJ A;  3AWF A;  3D1Q A;  2Q05 A;  1ZZW A;  3F9B A;  4MBB A;  3F9A A;  2B07 A;  2HCM A;  1XRI A;  1RXD A;  1EEN A;  1T4J A;  2OC3 A;  2CM8 A;  1G7G A;  1YTN A;  4BPC A;  3CM3 A;  3ZV2 A;  3AWE A;  3H2X A;  4QUN A;  5BX1 A;  2HXP A;  2G59 A;  5KA4 A;  4RHG A;  3F41 A;  4YAA A;  5BZX A;  2HC1 A;  1WRM A;  1FPZ A;  1JF7 A;  2HVL A;  2IMG A;  1LQF A;  3D1H A;  3O4U A;  1BZJ A;  4ERC A;  2CM2 A;  2J17 A;  4KYQ A;  5K22 A;  2I75 A;  5KA8 A;  4KI9 A;  3S3E A;  2CNH A;  2AZR A;  1XXP A;  5J8R A;  1A5Y A;  3EZZ A;  2H04 A;  2JJD A;  3S3F A;  2PBN A;  2FJN A;  3O3L A;  5KA2 A;  2F70 A;  1C84 A;  2G6Z A;  4GRZ A;  2F46 A;  1ZC0 A;  3O4T A;  5IBM A;  4OHD A;  3ZM1 A;  2CM3 A;  2B49 A;  1T49 A;  3EU0 A;  2Y2F A;  3QCB A;  1BZC A;  1Q6S A;  2R0B A;  3QCI A;  1XBO A;  1JLN A;  2CNF A;  2HB1 A;  5MMZ B;  2AHS A;  4QBE A;  4R0T A;  3QCL A;  4JNB A;  2Y96 A;  1KAK A;  2B4O A;  1U26 A;  2H4V A;  2F71 A;  1NWE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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