1Q6NA

The structure of phosphotyrosine phosphatase 1b in complex with compound 4
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
289
structure length
289
Chain Sequence
KLEFMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structural Basis for the Selectivity of Benzotriazole Inhibitors of Ptp1B
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein-tyrosine phosphatase, non-receptor type 1
total genus 98
structure length 289
sequence length 289
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2003-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1q6nA00
3S3EA 5GTJA 2I3RA 2CNIA 3V0EA 2H4KA 1YGUA 4GS0A 4BJOA 2H02A 1I57A 2BIJA 1P15A 2OC3A 1PTYA 5KABA 2QCJA 3BLTA 1XBOA 4WU2A 2I1YA 1NNYA 4HJQA 4J51A 4GE5A 1T49A 2VEXA 3F9AA 1OEUA 2Y2FA 4NWFA 4AZ1A 4RDDA 2B4PA 1LARA 1LQFA 3I7ZA 5M43A 2I6IA 1BZJA 2JJDA 3F9BA 4OHIA 3A5KA 5K22A 4ICZA 1Q6PA 4GFVA 3A5JA 2VEYA 1GWZA 1D5RA 3OLRA 1FPZA 2I6OA 2CMAA 1YZ4A 1YTSA 3QCGA 5KA8A 2AZRA 2I75A 3D44A 3EMUA 2PA5A 2M3VA 3V0IA 2B49A 4HRFA 1OESA 4QBWA 4NYHA 4YR8B 3SR9A 1QZ0A 4TVVA 2CMCA 2GWOA 2F71A 2NV5A 5HDEA 3BLUA 3S3KA 4GRZA 3O3LA 1C85A 5AWXA 5KA1A 1R6HA 5MMZB 4ZI4A 5J8RA 2A8BA 1OHDA 1I9TA 4H1OA 1Q1MA 1XXVA 2PSZA 1RXDA 1SUGA 3AWEA 1M3GA 4ERCA 1C86A 1PTTA 5K25A 2I6MA 1I9SA 1L8KA 5BX1A 3QCMA 1C83A 1PXHA 3F41A 2QEPA 3NMEA 4RKKA 2I6PA 2HB1A 2CNGA 4NWGA 3U96A 3V0HA 1YFOA 4GE6A 1Q6NA 3CM3A 4GWFA 1PH0A 1BZCA 3EB1A 2CNFA 2QCTA 1G7FA 1OEVA 5LXQB 2J17A 2NLKA 3ZM0A 4WOHA 4KI9A 5KACA 3QCKA 1U26A 2B4OA 2Q05A 2QBQA 5KAAA 4GFUA 1U25A 3QCBA 4QBEA 4QUMA 3ZV2A 2CM3A 4OHHA 3ZM3A 2PQ5A 2QDPA 2P6XA 1T48A 1G4US 2BV5A 2C7SA 2OUDA 4IKCA 2F6YA 4B04A 2BZLA 2QDCA 4Y14A 4BPCA 4ZRTA 3S3HA 2ZMMA 4R30A 1YTNA 2G59A 2CFVA 1PA1A 2J16B 2F6WA 3QCDA 3EZZA 2F6TA 2F6FA 3RGOA 4PYHA 3QCFA 3SMEA 2NT7A 1OETA 3QKQA 2YDUA 1ZZWA 1J4XA 2C46A 1U24A 3S4OA 1RPMA 4R0TA 1XRIA 4PVGA 2Q47A 2BGDA 2HC2A 4WU3A 1KAVA 3EAXA 1FPRA 4RH5A 3D42A 3QCHA 4Y2EA 2B07A 5KA3A 2SHPA 2A3KA 3O5XA 3O4UA 2HXPA 4RI5A 1PA9A 1XXPA 1YGRA 3I80A 1MKPA 3ZMPA 3AWGA 2HNQA 5BZZA 4RH9A 2WGPA 2AHSA 3B7OA 4DGPA 2B4UA 5KADA 4NNDA 4QUNA 3MOZA 1JLNA 5IBSA 5KA7A 1G4WR 1KAKA 2P4DA 2QBRA 2GP0A 5KA4A 4DGXA 1VHRA 4D3RA 3D1QA 2F46A 3N0AA 2FJNA 1YTWA 2HCMA 2I4EA 3S4EA 1AAXA 4WTYA 4MBBA 2NTAA 2R0BA 1Q6TA 2I42A 1PTVA 4GRYA 3QKPA 1WCHA 4GE2A 3QCCA 3EU0A 4YAAA 2E0TA 4D3QA 2I6JA 1OEMX 3D9CA 4OHEA 2B4SA 2FJMA 1L8GA 2CM8A 5EHRA 1ECVA 4JMJA 1Q6JA 5K24A 2CJZA 2H04A 3RZ2A 1LYVA 1C87A 2QDMA 2ZN7A 4QAHA 4RHGA 3V0GA 5BZXA 1OHCA 4OHDA 1PYNA 5BUGA 2I4GA 3AWFA 1YPTA 3GXGA 2I3UA 4R0SA 3M4UA 1C84A 1BZHA 2H4GA 4Z6BA 1ZCKA 2CM2A 2GJTA 2CM7A 3O4TA 1G1FA 1WAXA 2J16A 3F81A 4I8NA 2VEUA 2IMGA 3O4SA 2DXPA 3QCLA 1QXKA 2MBCA 4KYQA 2PT0A 2FH7A 2I5XA 2B3OA 3QCIA 1Q6SA 1A5YA 3QCEA 1EENA 3QCNA 4KYRA 1YN9A 4S0GA 3F99A 3S3FA 1ONZA 1JF7A 1G7GA 1ZCLA 2QBPA 3BM8A 1Q6MA 5KA9A 2BGEA 4JBCA 1PTUA 2CNHA 2RF6A 3V0JA 1WRMA 2CMBA 4JNBA 1FQ1A 1ONYA 2VEWA 1C88A 3D1OA 4HJPA 1V3AA 3RO1A 3ZMQA 2F6ZA 2NT2A 3I36A 1T4JA 1NWEA 2G6ZA 4JMKA 5K9VA 1NZ7A 2H03A 3MOWA 1NL9A 3OMHA 1OEOX 1G1GA 3V0DA 5K23A 2NZ6A 3BRHA 1X24A 5IBMA 2HVLA 5K9WA 1NO6A 2HC1A 2HNPA 3GXHA 5EHPA 2OOQA 5KA2A 3QCJA 4D3PA 1XM2A 2ESBA 3LJ8A 2PBNA 2VEVA 3RGQA 1EEOA 4ZN5A 2QBSA 3CWEA 4H34A 3ZM2A 2F6VA 2H4VA 2OZ5A 3ZM1A 2Y96A 5KA0A 2HY3A 1YWFA 4NX8A 1GFYA 2CNEA 3H2XA 5I6VA 1OHEA 2F70A 1NWLA 2I4HA 4OHLA 2PI7A 1ZC0A 3MMJA 1G1HA 4RI4A 3PS5A 3D1HA 3V0FA 4QAPA
chains in the Genus database with same CATH superfamily
3S3EA 5GTJA 2I3RA 2CNIA 3V0EA 2H4KA 1YGUA 4GS0A 4BJOA 1JBWA 2H02A 1I57A 2BIJA 1P15A 2OC3A 1PTYA 4QDIA 5KABA 2QCJA 4CVKA 3BLTA 1XBOA 4WU2A 2I1YA 1NNYA 4HJQA 4J51A 4GE5A 1T49A 2VEXA 3F9AA 1OEUA 2Y2FA 4NWFA 4AZ1A 4RDDA 2B4PA 1LARA 1LQFA 3I7ZA 5M43A 2I6IA 1BZJA 2JJDA 3F9BA 4OHIA 3A5KA 5K22A 4ICZA 1Q6PA 4GFVA 3A5JA 2VEYA 1GWZA 1D5RA 3OLRA 1FPZA 2I6OA 2CMAA 1YZ4A 1YTSA 3QCGA 3UAGA 5KA8A 4CVLA 2AZRA 2I75A 3D44A 3EMUA 2PA5A 2M3VA 3V0IA 2B49A 4HRFA 1OESA 4QBWA 4NYHA 4YR8B 3SR9A 1QZ0A 4TVVA 2CMCA 2GWOA 2F71A 2AM1A 2NV5A 5HDEA 3BLUA 3S3KA 4GRZA 3O3LA 1C85A 5AWXA 2GCBA 5KA1A 1R6HA 2F00A 5MMZB 4ZI4A 5J8RA 2A8BA 1OHDA 1I9TA 2JFHA 4H1OA 1Q1MA 1XXVA 2PSZA 1RXDA 1SUGA 3AWEA 1M3GA 4ERCA 1C86A 1PTTA 5K25A 2I6MA 2Y68A 1I9SA 1L8KA 5BX1A 3QCMA 1PXHA 1C83A 3F41A 2QEPA 3NMEA 4RKKA 2I6PA 2HB1A 2CNGA 4NWGA 3U96A 3V0HA 1YFOA 4GE6A 1Q6NA 3CM3A 3HN7A 4GWFA 1PH0A 1BZCA 3EB1A 2CNFA 2QCTA 1G7FA 1OEVA 5LXQB 2J17A 2AM2A 2NLKA 3ZM0A 4WOHA 4KI9A 5KACA 3QCKA 1U26A 2B4OA 2Q05A 2QBQA 5KAAA 4GFUA 1U25A 3QCBA 4QBEA 4QUMA 3ZV2A 2CM3A 4OHHA 1W7KA 2X5OA 3ZM3A 2PQ5A 2QDPA 2P6XA 1T48A 1G4US 2BV5A 2C7SA 2OUDA 4IKCA 2F6YA 4B04A 2UAGA 1E8CA 2BZLA 1W78A 2QDCA 4Y14A 4BPCA 4ZRTA 3S3HA 2ZMMA 4R30A 1YTNA 1E0DA 2G59A 2CFVA 1PA1A 2J16B 2F6WA 3QCDA 3EZZA 2F6TA 2F6FA 3RGOA 2WTZA 4PYHA 2UUOA 3QCFA 5A5FA 1GG4A 3SMEA 2NT7A 1OETA 3QKQA 2YDUA 1ZZWA 4CVMA 3ZM5A 1J4XA 2C46A 1U24A 4ZIYA 3S4OA 1RPMA 4R0TA 1XRIA 2VTEA 4BUBA 4PVGA 2Q47A 2BGDA 2HC2A 4WU3A 1KAVA 3EAXA 1FPRA 4RH5A 3D42A 4HV4A 3QCHA 3ZL8A 4Y2EA 2B07A 5KA3A 2SHPA 4UAGA 2A3KA 3O5XA 3O4UA 2HXPA 4RI5A 1PA9A 1XXPA 1YGRA 3I80A 1MKPA 3ZMPA 2GC6A 3AWGA 2HNQA 5BZZA 4RH9A 2WGPA 2AHSA 3B7OA 4DGPA 2B4UA 5KADA 4NNDA 2Y67A 4QUNA 3MOZA 1JLNA 1UAGA 5IBSA 5KA7A 1G4WR 1KAKA 2P4DA 2QBRA 2GP0A 5KA4A 4DGXA 1VHRA 4D3RA 3D1QA 2F46A 3N0AA 2FJNA 1YTWA 2HCMA 2I4EA 3S4EA 1AAXA 4WTYA 4C12A 4MBBA 2NTAA 2R0BA 1Q6TA 2I42A 1PTVA 4GRYA 3QKPA 1WCHA 4GE2A 3QCCA 3EU0A 4YAAA 2E0TA 4D3QA 2I6JA 1GQQA 1OEMX 3D9CA 4OHEA 2B4SA 2FJMA 1L8GA 2CM8A 2VORA 5EHRA 1ECVA 4JMJA 1Q6JA 5K24A 5A5EA 2CJZA 2H04A 3RZ2A 1LYVA 1C87A 2QDMA 2ZN7A 4QAHA 4RHGA 3V0GA 5BZXA 1OHCA 4OHDA 1PYNA 5BUGA 2I4GA 3LK7A 3AWFA 1YPTA 3GXGA 2I3UA 4R0SA 3M4UA 1C84A 1BZHA 2H4GA 4Z6BA 1ZCKA 2CM2A 2GJTA 2CM7A 3O4TA 1G1FA 3ZM6A 1WAXA 2J16A 3F81A 3NRSA 4I8NA 2VEUA 2IMGA 3O4SA 2DXPA 2XJAA 3QCLA 1QXKA 2MBCA 2Y1OA 4KYQA 2PT0A 2FH7A 2I5XA 2JFFA 2B3OA 2JFGA 3QCIA 2VOSA 1Q6SA 1A5YA 3QCEA 1EENA 3QCNA 4KYRA 1JBVA 1YN9A 4S0GA 3F99A 3S3FA 1ONZA 1O5ZA 3QCZA 1JF7A 1G7GA 1ZCLA 2QBPA 4QF5A 3MVNA 3BM8A 1Q6MA 5KA9A 2GC5A 2BGEA 4JBCA 1PTUA 1GQYA 2CNHA 2RF6A 3V0JA 1WRMA 2CMBA 4JNBA 1FQ1A 1ONYA 2VEWA 1C88A 3D1OA 4HJPA 1V3AA 3RO1A 3ZMQA 4C13A 2Y66A 2WJPA 2F6ZA 2NT2A 3I36A 1T4JA 1P3DA 1NWEA 2G6ZA 4JMKA 3PYZA 5K9VA 1NZ7A 2H03A 3MOWA 1NL9A 3OMHA 1EEHA 1OEOX 1G1GA 3V0DA 5K23A 2NZ6A 3BRHA 1X24A 5IBMA 2HVLA 5K9WA 1NO6A 2HC1A 3N2AA 2HNPA 3GXHA 5EHPA 2OOQA 5KA2A 3QCJA 4D3PA 1XM2A 2ESBA 3LJ8A 2PBNA 2VEVA 3RGQA 1EEOA 1P31A 4ZN5A 2UUPA 2QBSA 3CWEA 4H34A 3ZM2A 2F6VA 2H4VA 2OZ5A 3ZM1A 2Y96A 1FGSA 5KA0A 2HY3A 1YWFA 4NX8A 2VTDA 1GFYA 4BUCA 2CNEA 3H2XA 5I6VA 1OHEA 2F70A 1NWLA 2I4HA 4OHLA 2PI7A 2GCAA 1ZC0A 3MMJA 1J6UA 1G1HA 4RI4A 3PS5A 2XPCA 3D1HA 3V0FA 4QAPA
chains in the Genus database with same CATH topology
3S3EA 5GTJA 2I3RA 2CNIA 3V0EA 2H4KA 1YGUA 4GS0A 4BJOA 2H02A 1I57A 2BIJA 1P15A 2OC3A 1PTYA 5KABA 2QCJA 3BLTA 1XBOA 4WU2A 2I1YA 1NNYA 4HJQA 4J51A 4GE5A 1T49A 2VEXA 3F9AA 1OEUA 2Y2FA 4NWFA 4AZ1A 4RDDA 2B4PA 1LARA 1LQFA 3I7ZA 5M43A 2I6IA 1BZJA 2JJDA 3F9BA 4OHIA 3A5KA 5K22A 4ICZA 1Q6PA 4GFVA 3A5JA 2VEYA 1GWZA 1D5RA 3OLRA 1FPZA 2I6OA 2CMAA 1YZ4A 1YTSA 3QCGA 5KA8A 2AZRA 2I75A 3D44A 3EMUA 2PA5A 2M3VA 3V0IA 2B49A 4HRFA 1OESA 4QBWA 4NYHA 4YR8B 3SR9A 1QZ0A 4TVVA 2CMCA 2GWOA 2F71A 2NV5A 5HDEA 3BLUA 3S3KA 4GRZA 3O3LA 1C85A 5AWXA 5KA1A 1R6HA 5MMZB 4ZI4A 5J8RA 2A8BA 1OHDA 1I9TA 4H1OA 1Q1MA 1XXVA 2PSZA 1RXDA 1SUGA 3AWEA 1M3GA 4ERCA 1C86A 1PTTA 5K25A 2I6MA 1I9SA 1L8KA 5BX1A 3QCMA 1C83A 1PXHA 3F41A 2QEPA 3NMEA 4RKKA 2I6PA 2HB1A 2CNGA 4NWGA 3U96A 3V0HA 1YFOA 4GE6A 1Q6NA 3CM3A 4GWFA 1PH0A 1BZCA 3EB1A 2CNFA 2QCTA 1G7FA 1OEVA 5LXQB 2J17A 2NLKA 3ZM0A 4WOHA 4KI9A 5KACA 3QCKA 1U26A 2B4OA 2Q05A 2QBQA 5KAAA 4GFUA 1U25A 3QCBA 4QBEA 4QUMA 3ZV2A 2CM3A 4OHHA 3ZM3A 2PQ5A 2QDPA 2P6XA 1T48A 1G4US 2BV5A 2C7SA 2OUDA 4IKCA 2F6YA 4B04A 2BZLA 2QDCA 4Y14A 4BPCA 4ZRTA 3S3HA 2ZMMA 4R30A 1YTNA 2G59A 2CFVA 1PA1A 2J16B 2F6WA 3QCDA 3EZZA 2F6TA 2F6FA 3RGOA 4PYHA 3QCFA 3SMEA 2NT7A 1OETA 3QKQA 2YDUA 1ZZWA 1J4XA 2C46A 1U24A 3S4OA 1RPMA 4R0TA 1XRIA 4PVGA 2Q47A 2BGDA 2HC2A 4WU3A 1KAVA 3EAXA 1FPRA 4RH5A 3D42A 3QCHA 4Y2EA 2B07A 5KA3A 2SHPA 2A3KA 3O5XA 3O4UA 2HXPA 4RI5A 1PA9A 1XXPA 1YGRA 3I80A 1MKPA 3ZMPA 3AWGA 2HNQA 5BZZA 4RH9A 2WGPA 2AHSA 3B7OA 4DGPA 2B4UA 5KADA 4NNDA 4QUNA 3MOZA 1JLNA 5IBSA 5KA7A 1G4WR 1KAKA 2P4DA 2QBRA 2GP0A 5KA4A 4DGXA 1VHRA 4D3RA 3D1QA 2F46A 3N0AA 2FJNA 1YTWA 2HCMA 2I4EA 3S4EA 1AAXA 4WTYA 4MBBA 2NTAA 2R0BA 1Q6TA 2I42A 1PTVA 4GRYA 3QKPA 1WCHA 4GE2A 3QCCA 3EU0A 4YAAA 2E0TA 4D3QA 2I6JA 1OEMX 3D9CA 4OHEA 2B4SA 2FJMA 1L8GA 2CM8A 5EHRA 1ECVA 4JMJA 1Q6JA 5K24A 2CJZA 2H04A 3RZ2A 1LYVA 1C87A 2QDMA 2ZN7A 4QAHA 4RHGA 3V0GA 5BZXA 1OHCA 4OHDA 1PYNA 5BUGA 2I4GA 3AWFA 1YPTA 3GXGA 2I3UA 4R0SA 3M4UA 1C84A 1BZHA 2H4GA 4Z6BA 1ZCKA 2CM2A 2GJTA 2CM7A 3O4TA 1G1FA 1WAXA 2J16A 3F81A 4I8NA 2VEUA 2IMGA 3O4SA 2DXPA 3QCLA 1QXKA 2MBCA 4KYQA 2PT0A 2FH7A 2I5XA 2B3OA 3QCIA 1Q6SA 1A5YA 3QCEA 1EENA 3QCNA 4KYRA 1YN9A 4S0GA 3F99A 3S3FA 1ONZA 1JF7A 1G7GA 1ZCLA 2QBPA 3BM8A 1Q6MA 5KA9A 2BGEA 4JBCA 1PTUA 2CNHA 2RF6A 3V0JA 1WRMA 2CMBA 4JNBA 1FQ1A 1ONYA 2VEWA 1C88A 3D1OA 4HJPA 1V3AA 3RO1A 3ZMQA 2F6ZA 2NT2A 3I36A 1T4JA 1NWEA 2G6ZA 4JMKA 5K9VA 1NZ7A 2H03A 3MOWA 1NL9A 3OMHA 1OEOX 1G1GA 3V0DA 5K23A 2NZ6A 3BRHA 1X24A 5IBMA 2HVLA 5K9WA 1NO6A 2HC1A 2HNPA 3GXHA 5EHPA 2OOQA 5KA2A 3QCJA 4D3PA 1XM2A 2ESBA 3LJ8A 2PBNA 2VEVA 3RGQA 1EEOA 4ZN5A 2QBSA 3CWEA 4H34A 3ZM2A 2F6VA 2H4VA 2OZ5A 3ZM1A 2Y96A 5KA0A 2HY3A 1YWFA 4NX8A 1GFYA 2CNEA 3H2XA 5I6VA 1OHEA 2F70A 1NWLA 2I4HA 4OHLA 2PI7A 1ZC0A 3MMJA 1G1HA 4RI4A 3PS5A 3D1HA 3V0FA 4QAPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S3E A;  5GTJ A;  2I3R A;  2CNI A;  3V0E A;  2H4K A;  1YGU A;  4GS0 A;  4BJO A;  2H02 A;  1I57 A;  2BIJ A;  1P15 A;  2OC3 A;  1PTY A;  5KAB A;  2QCJ A;  3BLT A;  1XBO A;  4WU2 A;  2I1Y A;  1NNY A;  4HJQ A;  4J51 A;  4GE5 A;  1T49 A;  2VEX A;  3F9A A;  1OEU A;  2Y2F A;  4NWF A;  4AZ1 A;  4RDD A;  2B4P A;  1LAR A;  1LQF A;  3I7Z A;  5M43 A;  2I6I A;  1BZJ A;  2JJD A;  3F9B A;  4OHI A;  3A5K A;  5K22 A;  4ICZ A;  1Q6P A;  4GFV A;  3A5J A;  2VEY A;  1GWZ A;  1D5R A;  3OLR A;  1FPZ A;  2I6O A;  2CMA A;  1YZ4 A;  1YTS A;  3QCG A;  5KA8 A;  2AZR A;  2I75 A;  3D44 A;  3EMU A;  2PA5 A;  2M3V A;  3V0I A;  2B49 A;  4HRF A;  1OES A;  4QBW A;  4NYH A;  4YR8 B;  3SR9 A;  1QZ0 A;  4TVV A;  2CMC A;  2GWO A;  2F71 A;  2NV5 A;  5HDE A;  3BLU A;  3S3K A;  4GRZ A;  3O3L A;  1C85 A;  5AWX A;  5KA1 A;  1R6H A;  5MMZ B;  4ZI4 A;  5J8R A;  2A8B A;  1OHD A;  1I9T A;  4H1O A;  1Q1M A;  1XXV A;  2PSZ A;  1RXD A;  1SUG A;  3AWE A;  1M3G A;  4ERC A;  1C86 A;  1PTT A;  5K25 A;  2I6M A;  1I9S A;  1L8K A;  5BX1 A;  3QCM A;  1C83 A;  1PXH A;  3F41 A;  2QEP A;  3NME A;  4RKK A;  2I6P A;  2HB1 A;  2CNG A;  4NWG A;  3U96 A;  3V0H A;  1YFO A;  4GE6 A;  1Q6N A;  3CM3 A;  4GWF A;  1PH0 A;  1BZC A;  3EB1 A;  2CNF A;  2QCT A;  1G7F A;  1OEV A;  5LXQ B;  2J17 A;  2NLK A;  3ZM0 A;  4WOH A;  4KI9 A;  5KAC A;  3QCK A;  1U26 A;  2B4O A;  2Q05 A;  2QBQ A;  5KAA A;  4GFU A;  1U25 A;  3QCB A;  4QBE A;  4QUM A;  3ZV2 A;  2CM3 A;  4OHH A;  3ZM3 A;  2PQ5 A;  2QDP A;  2P6X A;  1T48 A;  1G4U S;  2BV5 A;  2C7S A;  2OUD A;  4IKC A;  2F6Y A;  4B04 A;  2BZL A;  2QDC A;  4Y14 A;  4BPC A;  4ZRT A;  3S3H A;  2ZMM A;  4R30 A;  1YTN A;  2G59 A;  2CFV A;  1PA1 A;  2J16 B;  2F6W A;  3QCD A;  3EZZ A;  2F6T A;  2F6F A;  3RGO A;  4PYH A;  3QCF A;  3SME A;  2NT7 A;  1OET A;  3QKQ A;  2YDU A;  1ZZW A;  1J4X A;  2C46 A;  1U24 A;  3S4O A;  1RPM A;  4R0T A;  1XRI A;  4PVG A;  2Q47 A;  2BGD A;  2HC2 A;  4WU3 A;  1KAV A;  3EAX A;  1FPR A;  4RH5 A;  3D42 A;  3QCH A;  4Y2E A;  2B07 A;  5KA3 A;  2SHP A;  2A3K A;  3O5X A;  3O4U A;  2HXP A;  4RI5 A;  1PA9 A;  1XXP A;  1YGR A;  3I80 A;  1MKP A;  3ZMP A;  3AWG A;  2HNQ A;  5BZZ A;  4RH9 A;  2WGP A;  2AHS A;  3B7O A;  4DGP A;  2B4U A;  5KAD A;  4NND A;  4QUN A;  3MOZ A;  1JLN A;  5IBS A;  5KA7 A;  1G4W R;  1KAK A;  2P4D A;  2QBR A;  2GP0 A;  5KA4 A;  4DGX A;  1VHR A;  4D3R A;  3D1Q A;  2F46 A;  3N0A A;  2FJN A;  1YTW A;  2HCM A;  2I4E A;  3S4E A;  1AAX A;  4WTY A;  4MBB A;  2NTA A;  2R0B A;  1Q6T A;  2I42 A;  1PTV A;  4GRY A;  3QKP A;  1WCH A;  4GE2 A;  3QCC A;  3EU0 A;  4YAA A;  2E0T A;  4D3Q A;  2I6J A;  1OEM X;  3D9C A;  4OHE A;  2B4S A;  2FJM A;  1L8G A;  2CM8 A;  5EHR A;  1ECV A;  4JMJ A;  1Q6J A;  5K24 A;  2CJZ A;  2H04 A;  3RZ2 A;  1LYV A;  1C87 A;  2QDM A;  2ZN7 A;  4QAH A;  4RHG A;  3V0G A;  5BZX A;  1OHC A;  4OHD A;  1PYN A;  5BUG A;  2I4G A;  3AWF A;  1YPT A;  3GXG A;  2I3U A;  4R0S A;  3M4U A;  1C84 A;  1BZH A;  2H4G A;  4Z6B A;  1ZCK A;  2CM2 A;  2GJT A;  2CM7 A;  3O4T A;  1G1F A;  1WAX A;  2J16 A;  3F81 A;  4I8N A;  2VEU A;  2IMG A;  3O4S A;  2DXP A;  3QCL A;  1QXK A;  2MBC A;  4KYQ A;  2PT0 A;  2FH7 A;  2I5X A;  2B3O A;  3QCI A;  1Q6S A;  1A5Y A;  3QCE A;  1EEN A;  3QCN A;  4KYR A;  1YN9 A;  4S0G A;  3F99 A;  3S3F A;  1ONZ A;  1JF7 A;  1G7G A;  1ZCL A;  2QBP A;  3BM8 A;  1Q6M A;  5KA9 A;  2BGE A;  4JBC A;  1PTU A;  2CNH A;  2RF6 A;  3V0J A;  1WRM A;  2CMB A;  4JNB A;  1FQ1 A;  1ONY A;  2VEW A;  1C88 A;  3D1O A;  4HJP A;  1V3A A;  3RO1 A;  3ZMQ A;  2F6Z A;  2NT2 A;  3I36 A;  1T4J A;  1NWE A;  2G6Z A;  4JMK A;  5K9V A;  1NZ7 A;  2H03 A;  3MOW A;  1NL9 A;  3OMH A;  1OEO X;  1G1G A;  3V0D A;  5K23 A;  2NZ6 A;  3BRH A;  1X24 A;  5IBM A;  2HVL A;  5K9W A;  1NO6 A;  2HC1 A;  2HNP A;  3GXH A;  5EHP A;  2OOQ A;  5KA2 A;  3QCJ A;  4D3P A;  1XM2 A;  2ESB A;  3LJ8 A;  2PBN A;  2VEV A;  3RGQ A;  1EEO A;  4ZN5 A;  2QBS A;  3CWE A;  4H34 A;  3ZM2 A;  2F6V A;  2H4V A;  2OZ5 A;  3ZM1 A;  2Y96 A;  5KA0 A;  2HY3 A;  1YWF A;  4NX8 A;  1GFY A;  2CNE A;  3H2X A;  5I6V A;  1OHE A;  2F70 A;  1NWL A;  2I4H A;  4OHL A;  2PI7 A;  1ZC0 A;  3MMJ A;  1G1H A;  4RI4 A;  3PS5 A;  3D1H A;  3V0F A;  4QAP A; 
#chains in the Genus database with same CATH topology
 3S3E A;  5GTJ A;  2I3R A;  2CNI A;  3V0E A;  2H4K A;  1YGU A;  4GS0 A;  4BJO A;  1JBW A;  2H02 A;  1I57 A;  2BIJ A;  1P15 A;  2OC3 A;  1PTY A;  4QDI A;  5KAB A;  2QCJ A;  4CVK A;  3BLT A;  1XBO A;  4WU2 A;  2I1Y A;  1NNY A;  4HJQ A;  4J51 A;  4GE5 A;  1T49 A;  2VEX A;  3F9A A;  1OEU A;  2Y2F A;  4NWF A;  4AZ1 A;  4RDD A;  2B4P A;  1LAR A;  1LQF A;  3I7Z A;  5M43 A;  2I6I A;  1BZJ A;  2JJD A;  3F9B A;  4OHI A;  3A5K A;  5K22 A;  4ICZ A;  1Q6P A;  4GFV A;  3A5J A;  2VEY A;  1GWZ A;  1D5R A;  3OLR A;  1FPZ A;  2I6O A;  2CMA A;  1YZ4 A;  1YTS A;  3QCG A;  3UAG A;  5KA8 A;  4CVL A;  2AZR A;  2I75 A;  3D44 A;  3EMU A;  2PA5 A;  2M3V A;  3V0I A;  2B49 A;  4HRF A;  1OES A;  4QBW A;  4NYH A;  4YR8 B;  3SR9 A;  1QZ0 A;  4TVV A;  2CMC A;  2GWO A;  2F71 A;  2AM1 A;  2NV5 A;  5HDE A;  3BLU A;  3S3K A;  4GRZ A;  3O3L A;  1C85 A;  5AWX A;  2GCB A;  5KA1 A;  1R6H A;  2F00 A;  5MMZ B;  4ZI4 A;  5J8R A;  2A8B A;  1OHD A;  1I9T A;  2JFH A;  4H1O A;  1Q1M A;  1XXV A;  2PSZ A;  1RXD A;  1SUG A;  3AWE A;  1M3G A;  4ERC A;  1C86 A;  1PTT A;  5K25 A;  2I6M A;  2Y68 A;  1I9S A;  1L8K A;  5BX1 A;  3QCM A;  1PXH A;  1C83 A;  3F41 A;  2QEP A;  3NME A;  4RKK A;  2I6P A;  2HB1 A;  2CNG A;  4NWG A;  3U96 A;  3V0H A;  1YFO A;  4GE6 A;  1Q6N A;  3CM3 A;  3HN7 A;  4GWF A;  1PH0 A;  1BZC A;  3EB1 A;  2CNF A;  2QCT A;  1G7F A;  1OEV A;  5LXQ B;  2J17 A;  2AM2 A;  2NLK A;  3ZM0 A;  4WOH A;  4KI9 A;  5KAC A;  3QCK A;  1U26 A;  2B4O A;  2Q05 A;  2QBQ A;  5KAA A;  4GFU A;  1U25 A;  3QCB A;  4QBE A;  4QUM A;  3ZV2 A;  2CM3 A;  4OHH A;  1W7K A;  2X5O A;  3ZM3 A;  2PQ5 A;  2QDP A;  2P6X A;  1T48 A;  1G4U S;  2BV5 A;  2C7S A;  2OUD A;  4IKC A;  2F6Y A;  4B04 A;  2UAG A;  1E8C A;  2BZL A;  1W78 A;  2QDC A;  4Y14 A;  4BPC A;  4ZRT A;  3S3H A;  2ZMM A;  4R30 A;  1YTN A;  1E0D A;  2G59 A;  2CFV A;  1PA1 A;  2J16 B;  2F6W A;  3QCD A;  3EZZ A;  2F6T A;  2F6F A;  3RGO A;  2WTZ A;  4PYH A;  2UUO A;  3QCF A;  5A5F A;  1GG4 A;  3SME A;  2NT7 A;  1OET A;  3QKQ A;  2YDU A;  1ZZW A;  4CVM A;  3ZM5 A;  1J4X A;  2C46 A;  1U24 A;  4ZIY A;  3S4O A;  1RPM A;  4R0T A;  1XRI A;  2VTE A;  4BUB A;  4PVG A;  2Q47 A;  2BGD A;  2HC2 A;  4WU3 A;  1KAV A;  3EAX A;  1FPR A;  4RH5 A;  3D42 A;  4HV4 A;  3QCH A;  3ZL8 A;  4Y2E A;  2B07 A;  5KA3 A;  2SHP A;  4UAG A;  2A3K A;  3O5X A;  3O4U A;  2HXP A;  4RI5 A;  1PA9 A;  1XXP A;  1YGR A;  3I80 A;  1MKP A;  3ZMP A;  2GC6 A;  3AWG A;  2HNQ A;  5BZZ A;  4RH9 A;  2WGP A;  2AHS A;  3B7O A;  4DGP A;  2B4U A;  5KAD A;  4NND A;  2Y67 A;  4QUN A;  3MOZ A;  1JLN A;  1UAG A;  5IBS A;  5KA7 A;  1G4W R;  1KAK A;  2P4D A;  2QBR A;  2GP0 A;  5KA4 A;  4DGX A;  1VHR A;  4D3R A;  3D1Q A;  2F46 A;  3N0A A;  2FJN A;  1YTW A;  2HCM A;  2I4E A;  3S4E A;  1AAX A;  4WTY A;  4C12 A;  4MBB A;  2NTA A;  2R0B A;  1Q6T A;  2I42 A;  1PTV A;  4GRY A;  3QKP A;  1WCH A;  4GE2 A;  3QCC A;  3EU0 A;  4YAA A;  2E0T A;  4D3Q A;  2I6J A;  1GQQ A;  1OEM X;  3D9C A;  4OHE A;  2B4S A;  2FJM A;  1L8G A;  2CM8 A;  2VOR A;  5EHR A;  1ECV A;  4JMJ A;  1Q6J A;  5K24 A;  5A5E A;  2CJZ A;  2H04 A;  3RZ2 A;  1LYV A;  1C87 A;  2QDM A;  2ZN7 A;  4QAH A;  4RHG A;  3V0G A;  5BZX A;  1OHC A;  4OHD A;  1PYN A;  5BUG A;  2I4G A;  3LK7 A;  3AWF A;  1YPT A;  3GXG A;  2I3U A;  4R0S A;  3M4U A;  1C84 A;  1BZH A;  2H4G A;  4Z6B A;  1ZCK A;  2CM2 A;  2GJT A;  2CM7 A;  3O4T A;  1G1F A;  3ZM6 A;  1WAX A;  2J16 A;  3F81 A;  3NRS A;  4I8N A;  2VEU A;  2IMG A;  3O4S A;  2DXP A;  2XJA A;  3QCL A;  1QXK A;  2MBC A;  2Y1O A;  4KYQ A;  2PT0 A;  2FH7 A;  2I5X A;  2JFF A;  2B3O A;  2JFG A;  3QCI A;  2VOS A;  1Q6S A;  1A5Y A;  3QCE A;  1EEN A;  3QCN A;  4KYR A;  1JBV A;  1YN9 A;  4S0G A;  3F99 A;  3S3F A;  1ONZ A;  1O5Z A;  3QCZ A;  1JF7 A;  1G7G A;  1ZCL A;  2QBP A;  4QF5 A;  3MVN A;  3BM8 A;  1Q6M A;  5KA9 A;  2GC5 A;  2BGE A;  4JBC A;  1PTU A;  1GQY A;  2CNH A;  2RF6 A;  3V0J A;  1WRM A;  2CMB A;  4JNB A;  1FQ1 A;  1ONY A;  2VEW A;  1C88 A;  3D1O A;  4HJP A;  1V3A A;  3RO1 A;  3ZMQ A;  4C13 A;  2Y66 A;  2WJP A;  2F6Z A;  2NT2 A;  3I36 A;  1T4J A;  1P3D A;  1NWE A;  2G6Z A;  4JMK A;  3PYZ A;  5K9V A;  1NZ7 A;  2H03 A;  3MOW A;  1NL9 A;  3OMH A;  1EEH A;  1OEO X;  1G1G A;  3V0D A;  5K23 A;  2NZ6 A;  3BRH A;  1X24 A;  5IBM A;  2HVL A;  5K9W A;  1NO6 A;  2HC1 A;  3N2A A;  2HNP A;  3GXH A;  5EHP A;  2OOQ A;  5KA2 A;  3QCJ A;  4D3P A;  1XM2 A;  2ESB A;  3LJ8 A;  2PBN A;  2VEV A;  3RGQ A;  1EEO A;  1P31 A;  4ZN5 A;  2UUP A;  2QBS A;  3CWE A;  4H34 A;  3ZM2 A;  2F6V A;  2H4V A;  2OZ5 A;  3ZM1 A;  2Y96 A;  1FGS A;  5KA0 A;  2HY3 A;  1YWF A;  4NX8 A;  2VTD A;  1GFY A;  4BUC A;  2CNE A;  3H2X A;  5I6V A;  1OHE A;  2F70 A;  1NWL A;  2I4H A;  4OHL A;  2PI7 A;  2GCA A;  1ZC0 A;  3MMJ A;  1J6U A;  1G1H A;  4RI4 A;  3PS5 A;  2XPC A;  3D1H A;  3V0F A;  4QAP A; 
#chains in the Genus database with same CATH homology
 3S3E A;  5GTJ A;  2I3R A;  2CNI A;  3V0E A;  2H4K A;  1YGU A;  4GS0 A;  4BJO A;  2H02 A;  1I57 A;  2BIJ A;  1P15 A;  2OC3 A;  1PTY A;  5KAB A;  2QCJ A;  3BLT A;  1XBO A;  4WU2 A;  2I1Y A;  1NNY A;  4HJQ A;  4J51 A;  4GE5 A;  1T49 A;  2VEX A;  3F9A A;  1OEU A;  2Y2F A;  4NWF A;  4AZ1 A;  4RDD A;  2B4P A;  1LAR A;  1LQF A;  3I7Z A;  5M43 A;  2I6I A;  1BZJ A;  2JJD A;  3F9B A;  4OHI A;  3A5K A;  5K22 A;  4ICZ A;  1Q6P A;  4GFV A;  3A5J A;  2VEY A;  1GWZ A;  1D5R A;  3OLR A;  1FPZ A;  2I6O A;  2CMA A;  1YZ4 A;  1YTS A;  3QCG A;  5KA8 A;  2AZR A;  2I75 A;  3D44 A;  3EMU A;  2PA5 A;  2M3V A;  3V0I A;  2B49 A;  4HRF A;  1OES A;  4QBW A;  4NYH A;  4YR8 B;  3SR9 A;  1QZ0 A;  4TVV A;  2CMC A;  2GWO A;  2F71 A;  2NV5 A;  5HDE A;  3BLU A;  3S3K A;  4GRZ A;  3O3L A;  1C85 A;  5AWX A;  5KA1 A;  1R6H A;  5MMZ B;  4ZI4 A;  5J8R A;  2A8B A;  1OHD A;  1I9T A;  4H1O A;  1Q1M A;  1XXV A;  2PSZ A;  1RXD A;  1SUG A;  3AWE A;  1M3G A;  4ERC A;  1C86 A;  1PTT A;  5K25 A;  2I6M A;  1I9S A;  1L8K A;  5BX1 A;  3QCM A;  1C83 A;  1PXH A;  3F41 A;  2QEP A;  3NME A;  4RKK A;  2I6P A;  2HB1 A;  2CNG A;  4NWG A;  3U96 A;  3V0H A;  1YFO A;  4GE6 A;  1Q6N A;  3CM3 A;  4GWF A;  1PH0 A;  1BZC A;  3EB1 A;  2CNF A;  2QCT A;  1G7F A;  1OEV A;  5LXQ B;  2J17 A;  2NLK A;  3ZM0 A;  4WOH A;  4KI9 A;  5KAC A;  3QCK A;  1U26 A;  2B4O A;  2Q05 A;  2QBQ A;  5KAA A;  4GFU A;  1U25 A;  3QCB A;  4QBE A;  4QUM A;  3ZV2 A;  2CM3 A;  4OHH A;  3ZM3 A;  2PQ5 A;  2QDP A;  2P6X A;  1T48 A;  1G4U S;  2BV5 A;  2C7S A;  2OUD A;  4IKC A;  2F6Y A;  4B04 A;  2BZL A;  2QDC A;  4Y14 A;  4BPC A;  4ZRT A;  3S3H A;  2ZMM A;  4R30 A;  1YTN A;  2G59 A;  2CFV A;  1PA1 A;  2J16 B;  2F6W A;  3QCD A;  3EZZ A;  2F6T A;  2F6F A;  3RGO A;  4PYH A;  3QCF A;  3SME A;  2NT7 A;  1OET A;  3QKQ A;  2YDU A;  1ZZW A;  1J4X A;  2C46 A;  1U24 A;  3S4O A;  1RPM A;  4R0T A;  1XRI A;  4PVG A;  2Q47 A;  2BGD A;  2HC2 A;  4WU3 A;  1KAV A;  3EAX A;  1FPR A;  4RH5 A;  3D42 A;  3QCH A;  4Y2E A;  2B07 A;  5KA3 A;  2SHP A;  2A3K A;  3O5X A;  3O4U A;  2HXP A;  4RI5 A;  1PA9 A;  1XXP A;  1YGR A;  3I80 A;  1MKP A;  3ZMP A;  3AWG A;  2HNQ A;  5BZZ A;  4RH9 A;  2WGP A;  2AHS A;  3B7O A;  4DGP A;  2B4U A;  5KAD A;  4NND A;  4QUN A;  3MOZ A;  1JLN A;  5IBS A;  5KA7 A;  1G4W R;  1KAK A;  2P4D A;  2QBR A;  2GP0 A;  5KA4 A;  4DGX A;  1VHR A;  4D3R A;  3D1Q A;  2F46 A;  3N0A A;  2FJN A;  1YTW A;  2HCM A;  2I4E A;  3S4E A;  1AAX A;  4WTY A;  4MBB A;  2NTA A;  2R0B A;  1Q6T A;  2I42 A;  1PTV A;  4GRY A;  3QKP A;  1WCH A;  4GE2 A;  3QCC A;  3EU0 A;  4YAA A;  2E0T A;  4D3Q A;  2I6J A;  1OEM X;  3D9C A;  4OHE A;  2B4S A;  2FJM A;  1L8G A;  2CM8 A;  5EHR A;  1ECV A;  4JMJ A;  1Q6J A;  5K24 A;  2CJZ A;  2H04 A;  3RZ2 A;  1LYV A;  1C87 A;  2QDM A;  2ZN7 A;  4QAH A;  4RHG A;  3V0G A;  5BZX A;  1OHC A;  4OHD A;  1PYN A;  5BUG A;  2I4G A;  3AWF A;  1YPT A;  3GXG A;  2I3U A;  4R0S A;  3M4U A;  1C84 A;  1BZH A;  2H4G A;  4Z6B A;  1ZCK A;  2CM2 A;  2GJT A;  2CM7 A;  3O4T A;  1G1F A;  1WAX A;  2J16 A;  3F81 A;  4I8N A;  2VEU A;  2IMG A;  3O4S A;  2DXP A;  3QCL A;  1QXK A;  2MBC A;  4KYQ A;  2PT0 A;  2FH7 A;  2I5X A;  2B3O A;  3QCI A;  1Q6S A;  1A5Y A;  3QCE A;  1EEN A;  3QCN A;  4KYR A;  1YN9 A;  4S0G A;  3F99 A;  3S3F A;  1ONZ A;  1JF7 A;  1G7G A;  1ZCL A;  2QBP A;  3BM8 A;  1Q6M A;  5KA9 A;  2BGE A;  4JBC A;  1PTU A;  2CNH A;  2RF6 A;  3V0J A;  1WRM A;  2CMB A;  4JNB A;  1FQ1 A;  1ONY A;  2VEW A;  1C88 A;  3D1O A;  4HJP A;  1V3A A;  3RO1 A;  3ZMQ A;  2F6Z A;  2NT2 A;  3I36 A;  1T4J A;  1NWE A;  2G6Z A;  4JMK A;  5K9V A;  1NZ7 A;  2H03 A;  3MOW A;  1NL9 A;  3OMH A;  1OEO X;  1G1G A;  3V0D A;  5K23 A;  2NZ6 A;  3BRH A;  1X24 A;  5IBM A;  2HVL A;  5K9W A;  1NO6 A;  2HC1 A;  2HNP A;  3GXH A;  5EHP A;  2OOQ A;  5KA2 A;  3QCJ A;  4D3P A;  1XM2 A;  2ESB A;  3LJ8 A;  2PBN A;  2VEV A;  3RGQ A;  1EEO A;  4ZN5 A;  2QBS A;  3CWE A;  4H34 A;  3ZM2 A;  2F6V A;  2H4V A;  2OZ5 A;  3ZM1 A;  2Y96 A;  5KA0 A;  2HY3 A;  1YWF A;  4NX8 A;  1GFY A;  2CNE A;  3H2X A;  5I6V A;  1OHE A;  2F70 A;  1NWL A;  2I4H A;  4OHL A;  2PI7 A;  1ZC0 A;  3MMJ A;  1G1H A;  4RI4 A;  3PS5 A;  3D1H A;  3V0F A;  4QAP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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