1T49A

Allosteric inhibition of protein tyrosine phosphatase 1b
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
282
structure length
282
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Allosteric inhibition of protein tyrosine phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein-tyrosine phosphatase, non-receptor type 1
total genus 96
structure length 282
sequence length 282
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2004-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1t49A00
4JNBA 2B4SA 1KAVA 2I6PA 2H03A 2C46A 2I1YA 5KA8A 2OUDA 1Q6TA 2RF6A 2HC1A 3CM3A 1BZHA 2I3RA 4QUMA 1QZ0A 2Q05A 2HC2A 5M43A 1Q6NA 1ZCLA 5K25A 5BUGA 2QBPA 1OHEA 5K9WA 2G6ZA 2F6ZA 2OC3A 2H04A 2QBRA 1NO6A 2FJMA 2NTAA 3U96A 5EHPA 3ZM0A 5BX1A 1PA9A 1XXPA 3D44A 4S0GA 4ZI4A 2HNQA 5GTJA 3F9BA 3S3FA 2NZ6A 1AAXA 5KA1A 1JLNA 1GFYA 1G1GA 3RGQA 4KI9A 2CMBA 4I8NA 2NLKA 2B4UA 3MOWA 2AZRA 3ZMPA 2I6OA 4D3RA 1YPTA 1Q6SA 2CM2A 1G7GA 3QCBA 3V0JA 2ESBA 4TVVA 2CNFA 2G59A 4ZRTA 1NNYA 2B49A 1Q1MA 3O3LA 2R0BA 3QCJA 2QDMA 3ZM3A 2WGPA 2FH7A 2CM3A 4QUNA 2I6JA 1VHRA 1OESA 4YAAA 1C88A 3S4OA 4KYRA 2CNIA 1MKPA 5I6VA 4BJOA 2BGDA 1Q6JA 2F46A 4RI4A 4B04A 3D1HA 3SR9A 5KA3A 3V0FA 2F6YA 1PTTA 5KACA 5HDEA 2F6FA 3RGOA 3I36A 3D1OA 5KA9A 2H02A 2SHPA 2BGEA 1NWEA 2DXPA 3O5XA 1FPZA 3QCFA 3S4EA 2CNHA 5KA2A 3F81A 1U25A 3MOZA 2FJNA 1JF7A 1OEUA 1ECVA 3I7ZA 1EEOA 2PBNA 2F6TA 3QCKA 5K23A 5KA4A 2F6VA 4GRZA 1U26A 2Y96A 1NZ7A 3H2XA 4RH5A 4DGPA 2BIJA 5AWXA 1XM2A 3S3KA 2ZMMA 2GP0A 3I80A 1I57A 1G1HA 1R6HA 2PI7A 2HVLA 1OEMX 1ONYA 4NX8A 4HRFA 2QBSA 3O4TA 1PA1A 4JBCA 2I4HA 2GWOA 2J17A 2JJDA 2BZLA 3QCEA 4H1OA 1YFOA 1PYNA 3LJ8A 4GE5A 3F99A 4HJPA 3BLTA 3ZM1A 2Y2FA 1D5RA 3EZZA 4KYQA 1G1FA 4OHLA 4ZN5A 2J16B 2HB1A 4GS0A 1OHCA 1XXVA 4WOHA 4WTYA 1C87A 4GE6A 1G4US 3QKQA 5J8RA 1V3AA 4GWFA 1QXKA 1G4WR 3O4SA 2QBQA 1ZC0A 1LQFA 1U24A 4YR8B 2C7SA 1GWZA 3AWEA 4GE2A 3EAXA 1OEVA 1RPMA 5EHRA 4PYHA 3V0EA 2PA5A 4NWGA 2E0TA 2H4KA 1YZ4A 3BRHA 3AWFA 3AWGA 1WRMA 3OLRA 2QDCA 4JMJA 2PQ5A 5K24A 2P6XA 3EMUA 4PVGA 1A5YA 3QCDA 3PS5A 4WU2A 1BZCA 2HNPA 4IKCA 2F6WA 1OEOX 1C86A 4HJQA 1RXDA 1YN9A 3S3HA 2CM8A 2CMCA 2A3KA 1OHDA 3D42A 1YGRA 4GRYA 2VEVA 5K22A 1J4XA 2B3OA 1Q6MA 1LARA 1T49A 2IMGA 1C83A 5KABA 4OHIA 1L8KA 1C84A 3V0HA 2CM7A 4BPCA 1YTSA 2ZN7A 2F70A 1I9SA 2I6IA 4RKKA 1ZCKA 2PSZA 4D3QA 1NWLA 3QCLA 1BZJA 2H4VA 4QAHA 4R30A 3ZMQA 1ZZWA 3QCHA 1OETA 4AZ1A 2QDPA 2I5XA 3QCGA 2QCJA 1Q6PA 5LXQB 2CFVA 3O4UA 3QCIA 5BZXA 4J51A 2VEXA 4DGXA 1I9TA 1PH0A 1PTUA 2OZ5A 4Z6BA 3SMEA 4GFVA 3V0DA 2CNGA 2I42A 3V0GA 2I4EA 2Q47A 1YTNA 5KA7A 1EENA 1PTYA 3QCCA 3B7OA 1XBOA 4MBBA 4D3PA 5KA0A 1T48A 2OOQA 1PXHA 1FPRA 2I6MA 4H34A 2MBCA 2HXPA 5KADA 2VEUA 3BM8A 3M4UA 2NT7A 3ZM2A 4RI5A 4RHGA 4OHEA 1FQ1A 3V0IA 2QCTA 1C85A 3F41A 3S3EA 2AHSA 3NMEA 4JMKA 1NL9A 2HY3A 3BLUA 3GXHA 2VEWA 1YGUA 4GFUA 5K9VA 2YDUA 3D9CA 4Y2EA 1ONZA 4NNDA 2BV5A 2H4GA 2HCMA 4R0TA 1M3GA 3A5KA 2J16A 2NT2A 2NV5A 3OMHA 4QBWA 3RZ2A 4Y14A 1PTVA 1L8GA 2A8BA 5BZZA 2VEYA 3EU0A 1SUGA 3GXGA 2I4GA 4QAPA 3RO1A 3QKPA 3D1QA 4QBEA 3QCMA 1X24A 2F71A 2QEPA 2CMAA 3MMJA 1YWFA 1G7FA 2GJTA 2I75A 4WU3A 5IBMA 4R0SA 2I3UA 4OHDA 3A5JA 2M3VA 3ZV2A 5KAAA 1P15A 5MMZB 1WCHA 1T4JA 3N0AA 4ICZA 1XRIA 5IBSA 3CWEA 3QCNA 2CJZA 1KAKA 2B4OA 3EB1A 1LYVA 2CNEA 4ERCA 2PT0A 4RDDA 3F9AA 2B07A 4NWFA 4OHHA 1WAXA 1YTWA 4NYHA 2P4DA 4RH9A 2B4PA
chains in the Genus database with same CATH superfamily
4JNBA 2B4SA 1KAVA 2I6PA 1JBWA 1UAGA 2H03A 2C46A 2I1YA 5KA8A 5A5FA 2OUDA 1Q6TA 2RF6A 2HC1A 3CM3A 1BZHA 2I3RA 4QUMA 1QZ0A 2Q05A 2HC2A 5M43A 1Q6NA 1ZCLA 5K25A 5BUGA 2QBPA 1OHEA 5K9WA 2G6ZA 2F6ZA 2OC3A 2H04A 2QBRA 1NO6A 2FJMA 2NTAA 3U96A 5EHPA 3ZM0A 5BX1A 1PA9A 4BUCA 1XXPA 3D44A 4S0GA 4ZI4A 2HNQA 5GTJA 3F9BA 3S3FA 4HV4A 2NZ6A 1AAXA 5KA1A 1JLNA 1GFYA 1G1GA 3RGQA 4KI9A 2CMBA 4I8NA 2NLKA 2B4UA 5A5EA 3MOWA 2AZRA 3ZMPA 1GG4A 2I6OA 4D3RA 2Y1OA 1YPTA 4UAGA 1Q6SA 2CM2A 3UAGA 1G7GA 3QCBA 3V0JA 2ESBA 4CVKA 1P3DA 4TVVA 2GCAA 2CNFA 2G59A 4ZRTA 1NNYA 2B49A 1O5ZA 1Q1MA 3O3LA 2R0BA 3QCJA 2QDMA 3ZM3A 2WGPA 2FH7A 2CM3A 4QUNA 2I6JA 3PYZA 1VHRA 1OESA 4YAAA 1C88A 3S4OA 4KYRA 2VTDA 2CNIA 1E8CA 1MKPA 5I6VA 4BJOA 2BGDA 1Q6JA 2F46A 4QDIA 4RI4A 3QCZA 4B04A 3D1HA 3SR9A 4C12A 5KA3A 3V0FA 2F6YA 1PTTA 5KACA 3MVNA 5HDEA 2F6FA 3RGOA 3I36A 3D1OA 5KA9A 2H02A 2SHPA 2BGEA 1NWEA 2DXPA 3O5XA 1FPZA 3QCFA 3S4EA 2CNHA 5KA2A 2AM2A 3F81A 1U25A 2VORA 3MOZA 2FJNA 1JF7A 1OEUA 2VTEA 1ECVA 2X5OA 3I7ZA 1EEOA 2PBNA 2F6TA 3QCKA 5K23A 5KA4A 2F6VA 4GRZA 2UUPA 1U26A 2Y96A 1NZ7A 2WTZA 3H2XA 4RH5A 4DGPA 3ZL8A 2BIJA 5AWXA 1FGSA 1XM2A 3S3KA 2ZMMA 2GP0A 3I80A 1I57A 1G1HA 1R6HA 2XJAA 2PI7A 2HVLA 1OEMX 1ONYA 2JFFA 4NX8A 4HRFA 2QBSA 3O4TA 1PA1A 4JBCA 2I4HA 2GWOA 2J17A 2JJDA 2BZLA 3QCEA 4H1OA 1YFOA 1PYNA 3LJ8A 4GE5A 3F99A 4HJPA 3BLTA 3ZM1A 2Y2FA 1D5RA 3EZZA 4KYQA 1G1FA 4OHLA 4ZN5A 2J16B 2HB1A 4GS0A 1OHCA 1XXVA 4WOHA 4WTYA 1C87A 4GE6A 1G4US 3QKQA 5J8RA 1V3AA 4GWFA 1QXKA 1G4WR 3O4SA 2QBQA 1ZC0A 1LQFA 1U24A 4YR8B 2C7SA 1GWZA 3AWEA 4GE2A 3EAXA 1OEVA 1RPMA 5EHRA 4PYHA 1GQYA 3V0EA 2PA5A 4NWGA 2JFGA 2E0TA 4CVMA 2H4KA 1W7KA 1EEHA 1YZ4A 3BRHA 3AWFA 3AWGA 1WRMA 3OLRA 2QDCA 4JMJA 2PQ5A 5K24A 2P6XA 3EMUA 4PVGA 1A5YA 3QCDA 3PS5A 4WU2A 1BZCA 2HNPA 4IKCA 2F6WA 1OEOX 1C86A 4HJQA 1RXDA 1YN9A 3S3HA 2CM8A 2CMCA 2A3KA 2XPCA 2AM1A 1OHDA 3D42A 1YGRA 4GRYA 2VEVA 2JFHA 5K22A 1J4XA 2B3OA 1Q6MA 1LARA 1T49A 2IMGA 1C83A 5KABA 4OHIA 1L8KA 1C84A 3HN7A 3V0HA 2CM7A 4BPCA 1YTSA 2ZN7A 2F70A 3ZM5A 1I9SA 2I6IA 4RKKA 1ZCKA 2PSZA 4C13A 4D3QA 4CVLA 1NWLA 3QCLA 1BZJA 1P31A 2H4VA 4QAHA 2WJPA 2GC5A 4R30A 3ZMQA 1ZZWA 3QCHA 1OETA 4AZ1A 2QDPA 2I5XA 3QCGA 2QCJA 1Q6PA 5LXQB 1J6UA 2CFVA 3O4UA 3QCIA 5BZXA 2Y66A 4J51A 2VEXA 4DGXA 1I9TA 1PH0A 1PTUA 2OZ5A 4Z6BA 3SMEA 4GFVA 3V0DA 2CNGA 2I42A 1E0DA 3V0GA 2I4EA 4QF5A 2Q47A 1YTNA 5KA7A 1EENA 1PTYA 3QCCA 3B7OA 1XBOA 2Y67A 4MBBA 3ZM6A 4D3PA 5KA0A 1T48A 2OOQA 1PXHA 3LK7A 2GC6A 1FPRA 2I6MA 4H34A 2MBCA 1JBVA 2HXPA 5KADA 2VEUA 3BM8A 3M4UA 2NT7A 3ZM2A 4RI5A 4RHGA 4OHEA 1FQ1A 3V0IA 2QCTA 1C85A 2VOSA 3F41A 3S3EA 2AHSA 3NMEA 4JMKA 4BUBA 2UUOA 1NL9A 2HY3A 3BLUA 2UAGA 2VEWA 1YGUA 3GXHA 4GFUA 5K9VA 2YDUA 3D9CA 4Y2EA 1ONZA 4NNDA 2BV5A 2H4GA 2HCMA 4R0TA 2F00A 1M3GA 3A5KA 2J16A 2NT2A 2NV5A 3OMHA 4QBWA 1W78A 2GCBA 3RZ2A 4Y14A 1PTVA 1L8GA 2A8BA 3NRSA 2VEYA 5BZZA 3EU0A 1SUGA 3GXGA 2I4GA 3N2AA 4QAPA 3RO1A 3QKPA 3D1QA 4QBEA 3QCMA 1X24A 2F71A 2QEPA 2CMAA 3MMJA 1YWFA 4ZIYA 1G7FA 2GJTA 2I75A 4WU3A 5IBMA 4R0SA 2I3UA 4OHDA 3A5JA 2M3VA 3ZV2A 5KAAA 1GQQA 1P15A 5MMZB 1WCHA 1T4JA 3N0AA 4ICZA 1XRIA 5IBSA 3CWEA 3QCNA 2CJZA 1KAKA 2B4OA 3EB1A 1LYVA 2CNEA 4ERCA 2PT0A 2Y68A 4RDDA 3F9AA 2B07A 4NWFA 4OHHA 1WAXA 1YTWA 4NYHA 2P4DA 4RH9A 2B4PA
chains in the Genus database with same CATH topology
4JNBA 2B4SA 1KAVA 2I6PA 2H03A 2C46A 2I1YA 5KA8A 2OUDA 1Q6TA 2RF6A 2HC1A 3CM3A 1BZHA 2I3RA 4QUMA 1QZ0A 2Q05A 2HC2A 5M43A 1Q6NA 1ZCLA 5K25A 5BUGA 2QBPA 1OHEA 5K9WA 2G6ZA 2F6ZA 2OC3A 2H04A 2QBRA 1NO6A 2FJMA 2NTAA 3U96A 5EHPA 3ZM0A 5BX1A 1PA9A 1XXPA 3D44A 4S0GA 4ZI4A 2HNQA 5GTJA 3F9BA 3S3FA 2NZ6A 1AAXA 5KA1A 1JLNA 1GFYA 1G1GA 3RGQA 4KI9A 2CMBA 4I8NA 2NLKA 2B4UA 3MOWA 2AZRA 3ZMPA 2I6OA 4D3RA 1YPTA 1Q6SA 2CM2A 1G7GA 3QCBA 3V0JA 2ESBA 4TVVA 2CNFA 2G59A 4ZRTA 1NNYA 2B49A 1Q1MA 3O3LA 2R0BA 3QCJA 2QDMA 3ZM3A 2WGPA 2FH7A 2CM3A 4QUNA 2I6JA 1VHRA 1OESA 4YAAA 1C88A 3S4OA 4KYRA 2CNIA 1MKPA 5I6VA 4BJOA 2BGDA 1Q6JA 2F46A 4RI4A 4B04A 3D1HA 3SR9A 5KA3A 3V0FA 2F6YA 1PTTA 5KACA 5HDEA 2F6FA 3RGOA 3I36A 3D1OA 5KA9A 2H02A 2SHPA 2BGEA 1NWEA 2DXPA 3O5XA 1FPZA 3QCFA 3S4EA 2CNHA 5KA2A 3F81A 1U25A 3MOZA 2FJNA 1JF7A 1OEUA 1ECVA 3I7ZA 1EEOA 2PBNA 2F6TA 3QCKA 5K23A 5KA4A 2F6VA 4GRZA 1U26A 2Y96A 1NZ7A 3H2XA 4RH5A 4DGPA 2BIJA 5AWXA 1XM2A 3S3KA 2ZMMA 2GP0A 3I80A 1I57A 1G1HA 1R6HA 2PI7A 2HVLA 1OEMX 1ONYA 4NX8A 4HRFA 2QBSA 3O4TA 1PA1A 4JBCA 2I4HA 2GWOA 2J17A 2JJDA 2BZLA 3QCEA 4H1OA 1YFOA 1PYNA 3LJ8A 4GE5A 3F99A 4HJPA 3BLTA 3ZM1A 2Y2FA 1D5RA 3EZZA 4KYQA 1G1FA 4OHLA 4ZN5A 2J16B 2HB1A 4GS0A 1OHCA 1XXVA 4WOHA 4WTYA 1C87A 4GE6A 1G4US 3QKQA 5J8RA 1V3AA 4GWFA 1QXKA 1G4WR 3O4SA 2QBQA 1ZC0A 1LQFA 1U24A 4YR8B 2C7SA 1GWZA 3AWEA 4GE2A 3EAXA 1OEVA 1RPMA 5EHRA 4PYHA 3V0EA 2PA5A 4NWGA 2E0TA 2H4KA 1YZ4A 3BRHA 3AWFA 3AWGA 1WRMA 3OLRA 2QDCA 4JMJA 2PQ5A 5K24A 2P6XA 3EMUA 4PVGA 1A5YA 3QCDA 3PS5A 4WU2A 1BZCA 2HNPA 4IKCA 2F6WA 1OEOX 1C86A 4HJQA 1RXDA 1YN9A 3S3HA 2CM8A 2CMCA 2A3KA 1OHDA 3D42A 1YGRA 4GRYA 2VEVA 5K22A 1J4XA 2B3OA 1Q6MA 1LARA 1T49A 2IMGA 1C83A 5KABA 4OHIA 1L8KA 1C84A 3V0HA 2CM7A 4BPCA 1YTSA 2ZN7A 2F70A 1I9SA 2I6IA 4RKKA 1ZCKA 2PSZA 4D3QA 1NWLA 3QCLA 1BZJA 2H4VA 4QAHA 4R30A 3ZMQA 1ZZWA 3QCHA 1OETA 4AZ1A 2QDPA 2I5XA 3QCGA 2QCJA 1Q6PA 5LXQB 2CFVA 3O4UA 3QCIA 5BZXA 4J51A 2VEXA 4DGXA 1I9TA 1PH0A 1PTUA 2OZ5A 4Z6BA 3SMEA 4GFVA 3V0DA 2CNGA 2I42A 3V0GA 2I4EA 2Q47A 1YTNA 5KA7A 1EENA 1PTYA 3QCCA 3B7OA 1XBOA 4MBBA 4D3PA 5KA0A 1T48A 2OOQA 1PXHA 1FPRA 2I6MA 4H34A 2MBCA 2HXPA 5KADA 2VEUA 3BM8A 3M4UA 2NT7A 3ZM2A 4RI5A 4RHGA 4OHEA 1FQ1A 3V0IA 2QCTA 1C85A 3F41A 3S3EA 2AHSA 3NMEA 4JMKA 1NL9A 2HY3A 3BLUA 3GXHA 2VEWA 1YGUA 4GFUA 5K9VA 2YDUA 3D9CA 4Y2EA 1ONZA 4NNDA 2BV5A 2H4GA 2HCMA 4R0TA 1M3GA 3A5KA 2J16A 2NT2A 2NV5A 3OMHA 4QBWA 3RZ2A 4Y14A 1PTVA 1L8GA 2A8BA 5BZZA 2VEYA 3EU0A 1SUGA 3GXGA 2I4GA 4QAPA 3RO1A 3QKPA 3D1QA 4QBEA 3QCMA 1X24A 2F71A 2QEPA 2CMAA 3MMJA 1YWFA 1G7FA 2GJTA 2I75A 4WU3A 5IBMA 4R0SA 2I3UA 4OHDA 3A5JA 2M3VA 3ZV2A 5KAAA 1P15A 5MMZB 1WCHA 1T4JA 3N0AA 4ICZA 1XRIA 5IBSA 3CWEA 3QCNA 2CJZA 1KAKA 2B4OA 3EB1A 1LYVA 2CNEA 4ERCA 2PT0A 4RDDA 3F9AA 2B07A 4NWFA 4OHHA 1WAXA 1YTWA 4NYHA 2P4DA 4RH9A 2B4PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JNB A;  2B4S A;  1KAV A;  2I6P A;  2H03 A;  2C46 A;  2I1Y A;  5KA8 A;  2OUD A;  1Q6T A;  2RF6 A;  2HC1 A;  3CM3 A;  1BZH A;  2I3R A;  4QUM A;  1QZ0 A;  2Q05 A;  2HC2 A;  5M43 A;  1Q6N A;  1ZCL A;  5K25 A;  5BUG A;  2QBP A;  1OHE A;  5K9W A;  2G6Z A;  2F6Z A;  2OC3 A;  2H04 A;  2QBR A;  1NO6 A;  2FJM A;  2NTA A;  3U96 A;  5EHP A;  3ZM0 A;  5BX1 A;  1PA9 A;  1XXP A;  3D44 A;  4S0G A;  4ZI4 A;  2HNQ A;  5GTJ A;  3F9B A;  3S3F A;  2NZ6 A;  1AAX A;  5KA1 A;  1JLN A;  1GFY A;  1G1G A;  3RGQ A;  4KI9 A;  2CMB A;  4I8N A;  2NLK A;  2B4U A;  3MOW A;  2AZR A;  3ZMP A;  2I6O A;  4D3R A;  1YPT A;  1Q6S A;  2CM2 A;  1G7G A;  3QCB A;  3V0J A;  2ESB A;  4TVV A;  2CNF A;  2G59 A;  4ZRT A;  1NNY A;  2B49 A;  1Q1M A;  3O3L A;  2R0B A;  3QCJ A;  2QDM A;  3ZM3 A;  2WGP A;  2FH7 A;  2CM3 A;  4QUN A;  2I6J A;  1VHR A;  1OES A;  4YAA A;  1C88 A;  3S4O A;  4KYR A;  2CNI A;  1MKP A;  5I6V A;  4BJO A;  2BGD A;  1Q6J A;  2F46 A;  4RI4 A;  4B04 A;  3D1H A;  3SR9 A;  5KA3 A;  3V0F A;  2F6Y A;  1PTT A;  5KAC A;  5HDE A;  2F6F A;  3RGO A;  3I36 A;  3D1O A;  5KA9 A;  2H02 A;  2SHP A;  2BGE A;  1NWE A;  2DXP A;  3O5X A;  1FPZ A;  3QCF A;  3S4E A;  2CNH A;  5KA2 A;  3F81 A;  1U25 A;  3MOZ A;  2FJN A;  1JF7 A;  1OEU A;  1ECV A;  3I7Z A;  1EEO A;  2PBN A;  2F6T A;  3QCK A;  5K23 A;  5KA4 A;  2F6V A;  4GRZ A;  1U26 A;  2Y96 A;  1NZ7 A;  3H2X A;  4RH5 A;  4DGP A;  2BIJ A;  5AWX A;  1XM2 A;  3S3K A;  2ZMM A;  2GP0 A;  3I80 A;  1I57 A;  1G1H A;  1R6H A;  2PI7 A;  2HVL A;  1OEM X;  1ONY A;  4NX8 A;  4HRF A;  2QBS A;  3O4T A;  1PA1 A;  4JBC A;  2I4H A;  2GWO A;  2J17 A;  2JJD A;  2BZL A;  3QCE A;  4H1O A;  1YFO A;  1PYN A;  3LJ8 A;  4GE5 A;  3F99 A;  4HJP A;  3BLT A;  3ZM1 A;  2Y2F A;  1D5R A;  3EZZ A;  4KYQ A;  1G1F A;  4OHL A;  4ZN5 A;  2J16 B;  2HB1 A;  4GS0 A;  1OHC A;  1XXV A;  4WOH A;  4WTY A;  1C87 A;  4GE6 A;  1G4U S;  3QKQ A;  5J8R A;  1V3A A;  4GWF A;  1QXK A;  1G4W R;  3O4S A;  2QBQ A;  1ZC0 A;  1LQF A;  1U24 A;  4YR8 B;  2C7S A;  1GWZ A;  3AWE A;  4GE2 A;  3EAX A;  1OEV A;  1RPM A;  5EHR A;  4PYH A;  3V0E A;  2PA5 A;  4NWG A;  2E0T A;  2H4K A;  1YZ4 A;  3BRH A;  3AWF A;  3AWG A;  1WRM A;  3OLR A;  2QDC A;  4JMJ A;  2PQ5 A;  5K24 A;  2P6X A;  3EMU A;  4PVG A;  1A5Y A;  3QCD A;  3PS5 A;  4WU2 A;  1BZC A;  2HNP A;  4IKC A;  2F6W A;  1OEO X;  1C86 A;  4HJQ A;  1RXD A;  1YN9 A;  3S3H A;  2CM8 A;  2CMC A;  2A3K A;  1OHD A;  3D42 A;  1YGR A;  4GRY A;  2VEV A;  5K22 A;  1J4X A;  2B3O A;  1Q6M A;  1LAR A;  1T49 A;  2IMG A;  1C83 A;  5KAB A;  4OHI A;  1L8K A;  1C84 A;  3V0H A;  2CM7 A;  4BPC A;  1YTS A;  2ZN7 A;  2F70 A;  1I9S A;  2I6I A;  4RKK A;  1ZCK A;  2PSZ A;  4D3Q A;  1NWL A;  3QCL A;  1BZJ A;  2H4V A;  4QAH A;  4R30 A;  3ZMQ A;  1ZZW A;  3QCH A;  1OET A;  4AZ1 A;  2QDP A;  2I5X A;  3QCG A;  2QCJ A;  1Q6P A;  5LXQ B;  2CFV A;  3O4U A;  3QCI A;  5BZX A;  4J51 A;  2VEX A;  4DGX A;  1I9T A;  1PH0 A;  1PTU A;  2OZ5 A;  4Z6B A;  3SME A;  4GFV A;  3V0D A;  2CNG A;  2I42 A;  3V0G A;  2I4E A;  2Q47 A;  1YTN A;  5KA7 A;  1EEN A;  1PTY A;  3QCC A;  3B7O A;  1XBO A;  4MBB A;  4D3P A;  5KA0 A;  1T48 A;  2OOQ A;  1PXH A;  1FPR A;  2I6M A;  4H34 A;  2MBC A;  2HXP A;  5KAD A;  2VEU A;  3BM8 A;  3M4U A;  2NT7 A;  3ZM2 A;  4RI5 A;  4RHG A;  4OHE A;  1FQ1 A;  3V0I A;  2QCT A;  1C85 A;  3F41 A;  3S3E A;  2AHS A;  3NME A;  4JMK A;  1NL9 A;  2HY3 A;  3BLU A;  3GXH A;  2VEW A;  1YGU A;  4GFU A;  5K9V A;  2YDU A;  3D9C A;  4Y2E A;  1ONZ A;  4NND A;  2BV5 A;  2H4G A;  2HCM A;  4R0T A;  1M3G A;  3A5K A;  2J16 A;  2NT2 A;  2NV5 A;  3OMH A;  4QBW A;  3RZ2 A;  4Y14 A;  1PTV A;  1L8G A;  2A8B A;  5BZZ A;  2VEY A;  3EU0 A;  1SUG A;  3GXG A;  2I4G A;  4QAP A;  3RO1 A;  3QKP A;  3D1Q A;  4QBE A;  3QCM A;  1X24 A;  2F71 A;  2QEP A;  2CMA A;  3MMJ A;  1YWF A;  1G7F A;  2GJT A;  2I75 A;  4WU3 A;  5IBM A;  4R0S A;  2I3U A;  4OHD A;  3A5J A;  2M3V A;  3ZV2 A;  5KAA A;  1P15 A;  5MMZ B;  1WCH A;  1T4J A;  3N0A A;  4ICZ A;  1XRI A;  5IBS A;  3CWE A;  3QCN A;  2CJZ A;  1KAK A;  2B4O A;  3EB1 A;  1LYV A;  2CNE A;  4ERC A;  2PT0 A;  4RDD A;  3F9A A;  2B07 A;  4NWF A;  4OHH A;  1WAX A;  1YTW A;  4NYH A;  2P4D A;  4RH9 A;  2B4P A; 
#chains in the Genus database with same CATH topology
 4JNB A;  2B4S A;  1KAV A;  2I6P A;  1JBW A;  1UAG A;  2H03 A;  2C46 A;  2I1Y A;  5KA8 A;  5A5F A;  2OUD A;  1Q6T A;  2RF6 A;  2HC1 A;  3CM3 A;  1BZH A;  2I3R A;  4QUM A;  1QZ0 A;  2Q05 A;  2HC2 A;  5M43 A;  1Q6N A;  1ZCL A;  5K25 A;  5BUG A;  2QBP A;  1OHE A;  5K9W A;  2G6Z A;  2F6Z A;  2OC3 A;  2H04 A;  2QBR A;  1NO6 A;  2FJM A;  2NTA A;  3U96 A;  5EHP A;  3ZM0 A;  5BX1 A;  1PA9 A;  4BUC A;  1XXP A;  3D44 A;  4S0G A;  4ZI4 A;  2HNQ A;  5GTJ A;  3F9B A;  3S3F A;  4HV4 A;  2NZ6 A;  1AAX A;  5KA1 A;  1JLN A;  1GFY A;  1G1G A;  3RGQ A;  4KI9 A;  2CMB A;  4I8N A;  2NLK A;  2B4U A;  5A5E A;  3MOW A;  2AZR A;  3ZMP A;  1GG4 A;  2I6O A;  4D3R A;  2Y1O A;  1YPT A;  4UAG A;  1Q6S A;  2CM2 A;  3UAG A;  1G7G A;  3QCB A;  3V0J A;  2ESB A;  4CVK A;  1P3D A;  4TVV A;  2GCA A;  2CNF A;  2G59 A;  4ZRT A;  1NNY A;  2B49 A;  1O5Z A;  1Q1M A;  3O3L A;  2R0B A;  3QCJ A;  2QDM A;  3ZM3 A;  2WGP A;  2FH7 A;  2CM3 A;  4QUN A;  2I6J A;  3PYZ A;  1VHR A;  1OES A;  4YAA A;  1C88 A;  3S4O A;  4KYR A;  2VTD A;  2CNI A;  1E8C A;  1MKP A;  5I6V A;  4BJO A;  2BGD A;  1Q6J A;  2F46 A;  4QDI A;  4RI4 A;  3QCZ A;  4B04 A;  3D1H A;  3SR9 A;  4C12 A;  5KA3 A;  3V0F A;  2F6Y A;  1PTT A;  5KAC A;  3MVN A;  5HDE A;  2F6F A;  3RGO A;  3I36 A;  3D1O A;  5KA9 A;  2H02 A;  2SHP A;  2BGE A;  1NWE A;  2DXP A;  3O5X A;  1FPZ A;  3QCF A;  3S4E A;  2CNH A;  5KA2 A;  2AM2 A;  3F81 A;  1U25 A;  2VOR A;  3MOZ A;  2FJN A;  1JF7 A;  1OEU A;  2VTE A;  1ECV A;  2X5O A;  3I7Z A;  1EEO A;  2PBN A;  2F6T A;  3QCK A;  5K23 A;  5KA4 A;  2F6V A;  4GRZ A;  2UUP A;  1U26 A;  2Y96 A;  1NZ7 A;  2WTZ A;  3H2X A;  4RH5 A;  4DGP A;  3ZL8 A;  2BIJ A;  5AWX A;  1FGS A;  1XM2 A;  3S3K A;  2ZMM A;  2GP0 A;  3I80 A;  1I57 A;  1G1H A;  1R6H A;  2XJA A;  2PI7 A;  2HVL A;  1OEM X;  1ONY A;  2JFF A;  4NX8 A;  4HRF A;  2QBS A;  3O4T A;  1PA1 A;  4JBC A;  2I4H A;  2GWO A;  2J17 A;  2JJD A;  2BZL A;  3QCE A;  4H1O A;  1YFO A;  1PYN A;  3LJ8 A;  4GE5 A;  3F99 A;  4HJP A;  3BLT A;  3ZM1 A;  2Y2F A;  1D5R A;  3EZZ A;  4KYQ A;  1G1F A;  4OHL A;  4ZN5 A;  2J16 B;  2HB1 A;  4GS0 A;  1OHC A;  1XXV A;  4WOH A;  4WTY A;  1C87 A;  4GE6 A;  1G4U S;  3QKQ A;  5J8R A;  1V3A A;  4GWF A;  1QXK A;  1G4W R;  3O4S A;  2QBQ A;  1ZC0 A;  1LQF A;  1U24 A;  4YR8 B;  2C7S A;  1GWZ A;  3AWE A;  4GE2 A;  3EAX A;  1OEV A;  1RPM A;  5EHR A;  4PYH A;  1GQY A;  3V0E A;  2PA5 A;  4NWG A;  2JFG A;  2E0T A;  4CVM A;  2H4K A;  1W7K A;  1EEH A;  1YZ4 A;  3BRH A;  3AWF A;  3AWG A;  1WRM A;  3OLR A;  2QDC A;  4JMJ A;  2PQ5 A;  5K24 A;  2P6X A;  3EMU A;  4PVG A;  1A5Y A;  3QCD A;  3PS5 A;  4WU2 A;  1BZC A;  2HNP A;  4IKC A;  2F6W A;  1OEO X;  1C86 A;  4HJQ A;  1RXD A;  1YN9 A;  3S3H A;  2CM8 A;  2CMC A;  2A3K A;  2XPC A;  2AM1 A;  1OHD A;  3D42 A;  1YGR A;  4GRY A;  2VEV A;  2JFH A;  5K22 A;  1J4X A;  2B3O A;  1Q6M A;  1LAR A;  1T49 A;  2IMG A;  1C83 A;  5KAB A;  4OHI A;  1L8K A;  1C84 A;  3HN7 A;  3V0H A;  2CM7 A;  4BPC A;  1YTS A;  2ZN7 A;  2F70 A;  3ZM5 A;  1I9S A;  2I6I A;  4RKK A;  1ZCK A;  2PSZ A;  4C13 A;  4D3Q A;  4CVL A;  1NWL A;  3QCL A;  1BZJ A;  1P31 A;  2H4V A;  4QAH A;  2WJP A;  2GC5 A;  4R30 A;  3ZMQ A;  1ZZW A;  3QCH A;  1OET A;  4AZ1 A;  2QDP A;  2I5X A;  3QCG A;  2QCJ A;  1Q6P A;  5LXQ B;  1J6U A;  2CFV A;  3O4U A;  3QCI A;  5BZX A;  2Y66 A;  4J51 A;  2VEX A;  4DGX A;  1I9T A;  1PH0 A;  1PTU A;  2OZ5 A;  4Z6B A;  3SME A;  4GFV A;  3V0D A;  2CNG A;  2I42 A;  1E0D A;  3V0G A;  2I4E A;  4QF5 A;  2Q47 A;  1YTN A;  5KA7 A;  1EEN A;  1PTY A;  3QCC A;  3B7O A;  1XBO A;  2Y67 A;  4MBB A;  3ZM6 A;  4D3P A;  5KA0 A;  1T48 A;  2OOQ A;  1PXH A;  3LK7 A;  2GC6 A;  1FPR A;  2I6M A;  4H34 A;  2MBC A;  1JBV A;  2HXP A;  5KAD A;  2VEU A;  3BM8 A;  3M4U A;  2NT7 A;  3ZM2 A;  4RI5 A;  4RHG A;  4OHE A;  1FQ1 A;  3V0I A;  2QCT A;  1C85 A;  2VOS A;  3F41 A;  3S3E A;  2AHS A;  3NME A;  4JMK A;  4BUB A;  2UUO A;  1NL9 A;  2HY3 A;  3BLU A;  2UAG A;  2VEW A;  1YGU A;  3GXH A;  4GFU A;  5K9V A;  2YDU A;  3D9C A;  4Y2E A;  1ONZ A;  4NND A;  2BV5 A;  2H4G A;  2HCM A;  4R0T A;  2F00 A;  1M3G A;  3A5K A;  2J16 A;  2NT2 A;  2NV5 A;  3OMH A;  4QBW A;  1W78 A;  2GCB A;  3RZ2 A;  4Y14 A;  1PTV A;  1L8G A;  2A8B A;  3NRS A;  2VEY A;  5BZZ A;  3EU0 A;  1SUG A;  3GXG A;  2I4G A;  3N2A A;  4QAP A;  3RO1 A;  3QKP A;  3D1Q A;  4QBE A;  3QCM A;  1X24 A;  2F71 A;  2QEP A;  2CMA A;  3MMJ A;  1YWF A;  4ZIY A;  1G7F A;  2GJT A;  2I75 A;  4WU3 A;  5IBM A;  4R0S A;  2I3U A;  4OHD A;  3A5J A;  2M3V A;  3ZV2 A;  5KAA A;  1GQQ A;  1P15 A;  5MMZ B;  1WCH A;  1T4J A;  3N0A A;  4ICZ A;  1XRI A;  5IBS A;  3CWE A;  3QCN A;  2CJZ A;  1KAK A;  2B4O A;  3EB1 A;  1LYV A;  2CNE A;  4ERC A;  2PT0 A;  2Y68 A;  4RDD A;  3F9A A;  2B07 A;  4NWF A;  4OHH A;  1WAX A;  1YTW A;  4NYH A;  2P4D A;  4RH9 A;  2B4P A; 
#chains in the Genus database with same CATH homology
 4JNB A;  2B4S A;  1KAV A;  2I6P A;  2H03 A;  2C46 A;  2I1Y A;  5KA8 A;  2OUD A;  1Q6T A;  2RF6 A;  2HC1 A;  3CM3 A;  1BZH A;  2I3R A;  4QUM A;  1QZ0 A;  2Q05 A;  2HC2 A;  5M43 A;  1Q6N A;  1ZCL A;  5K25 A;  5BUG A;  2QBP A;  1OHE A;  5K9W A;  2G6Z A;  2F6Z A;  2OC3 A;  2H04 A;  2QBR A;  1NO6 A;  2FJM A;  2NTA A;  3U96 A;  5EHP A;  3ZM0 A;  5BX1 A;  1PA9 A;  1XXP A;  3D44 A;  4S0G A;  4ZI4 A;  2HNQ A;  5GTJ A;  3F9B A;  3S3F A;  2NZ6 A;  1AAX A;  5KA1 A;  1JLN A;  1GFY A;  1G1G A;  3RGQ A;  4KI9 A;  2CMB A;  4I8N A;  2NLK A;  2B4U A;  3MOW A;  2AZR A;  3ZMP A;  2I6O A;  4D3R A;  1YPT A;  1Q6S A;  2CM2 A;  1G7G A;  3QCB A;  3V0J A;  2ESB A;  4TVV A;  2CNF A;  2G59 A;  4ZRT A;  1NNY A;  2B49 A;  1Q1M A;  3O3L A;  2R0B A;  3QCJ A;  2QDM A;  3ZM3 A;  2WGP A;  2FH7 A;  2CM3 A;  4QUN A;  2I6J A;  1VHR A;  1OES A;  4YAA A;  1C88 A;  3S4O A;  4KYR A;  2CNI A;  1MKP A;  5I6V A;  4BJO A;  2BGD A;  1Q6J A;  2F46 A;  4RI4 A;  4B04 A;  3D1H A;  3SR9 A;  5KA3 A;  3V0F A;  2F6Y A;  1PTT A;  5KAC A;  5HDE A;  2F6F A;  3RGO A;  3I36 A;  3D1O A;  5KA9 A;  2H02 A;  2SHP A;  2BGE A;  1NWE A;  2DXP A;  3O5X A;  1FPZ A;  3QCF A;  3S4E A;  2CNH A;  5KA2 A;  3F81 A;  1U25 A;  3MOZ A;  2FJN A;  1JF7 A;  1OEU A;  1ECV A;  3I7Z A;  1EEO A;  2PBN A;  2F6T A;  3QCK A;  5K23 A;  5KA4 A;  2F6V A;  4GRZ A;  1U26 A;  2Y96 A;  1NZ7 A;  3H2X A;  4RH5 A;  4DGP A;  2BIJ A;  5AWX A;  1XM2 A;  3S3K A;  2ZMM A;  2GP0 A;  3I80 A;  1I57 A;  1G1H A;  1R6H A;  2PI7 A;  2HVL A;  1OEM X;  1ONY A;  4NX8 A;  4HRF A;  2QBS A;  3O4T A;  1PA1 A;  4JBC A;  2I4H A;  2GWO A;  2J17 A;  2JJD A;  2BZL A;  3QCE A;  4H1O A;  1YFO A;  1PYN A;  3LJ8 A;  4GE5 A;  3F99 A;  4HJP A;  3BLT A;  3ZM1 A;  2Y2F A;  1D5R A;  3EZZ A;  4KYQ A;  1G1F A;  4OHL A;  4ZN5 A;  2J16 B;  2HB1 A;  4GS0 A;  1OHC A;  1XXV A;  4WOH A;  4WTY A;  1C87 A;  4GE6 A;  1G4U S;  3QKQ A;  5J8R A;  1V3A A;  4GWF A;  1QXK A;  1G4W R;  3O4S A;  2QBQ A;  1ZC0 A;  1LQF A;  1U24 A;  4YR8 B;  2C7S A;  1GWZ A;  3AWE A;  4GE2 A;  3EAX A;  1OEV A;  1RPM A;  5EHR A;  4PYH A;  3V0E A;  2PA5 A;  4NWG A;  2E0T A;  2H4K A;  1YZ4 A;  3BRH A;  3AWF A;  3AWG A;  1WRM A;  3OLR A;  2QDC A;  4JMJ A;  2PQ5 A;  5K24 A;  2P6X A;  3EMU A;  4PVG A;  1A5Y A;  3QCD A;  3PS5 A;  4WU2 A;  1BZC A;  2HNP A;  4IKC A;  2F6W A;  1OEO X;  1C86 A;  4HJQ A;  1RXD A;  1YN9 A;  3S3H A;  2CM8 A;  2CMC A;  2A3K A;  1OHD A;  3D42 A;  1YGR A;  4GRY A;  2VEV A;  5K22 A;  1J4X A;  2B3O A;  1Q6M A;  1LAR A;  1T49 A;  2IMG A;  1C83 A;  5KAB A;  4OHI A;  1L8K A;  1C84 A;  3V0H A;  2CM7 A;  4BPC A;  1YTS A;  2ZN7 A;  2F70 A;  1I9S A;  2I6I A;  4RKK A;  1ZCK A;  2PSZ A;  4D3Q A;  1NWL A;  3QCL A;  1BZJ A;  2H4V A;  4QAH A;  4R30 A;  3ZMQ A;  1ZZW A;  3QCH A;  1OET A;  4AZ1 A;  2QDP A;  2I5X A;  3QCG A;  2QCJ A;  1Q6P A;  5LXQ B;  2CFV A;  3O4U A;  3QCI A;  5BZX A;  4J51 A;  2VEX A;  4DGX A;  1I9T A;  1PH0 A;  1PTU A;  2OZ5 A;  4Z6B A;  3SME A;  4GFV A;  3V0D A;  2CNG A;  2I42 A;  3V0G A;  2I4E A;  2Q47 A;  1YTN A;  5KA7 A;  1EEN A;  1PTY A;  3QCC A;  3B7O A;  1XBO A;  4MBB A;  4D3P A;  5KA0 A;  1T48 A;  2OOQ A;  1PXH A;  1FPR A;  2I6M A;  4H34 A;  2MBC A;  2HXP A;  5KAD A;  2VEU A;  3BM8 A;  3M4U A;  2NT7 A;  3ZM2 A;  4RI5 A;  4RHG A;  4OHE A;  1FQ1 A;  3V0I A;  2QCT A;  1C85 A;  3F41 A;  3S3E A;  2AHS A;  3NME A;  4JMK A;  1NL9 A;  2HY3 A;  3BLU A;  3GXH A;  2VEW A;  1YGU A;  4GFU A;  5K9V A;  2YDU A;  3D9C A;  4Y2E A;  1ONZ A;  4NND A;  2BV5 A;  2H4G A;  2HCM A;  4R0T A;  1M3G A;  3A5K A;  2J16 A;  2NT2 A;  2NV5 A;  3OMH A;  4QBW A;  3RZ2 A;  4Y14 A;  1PTV A;  1L8G A;  2A8B A;  5BZZ A;  2VEY A;  3EU0 A;  1SUG A;  3GXG A;  2I4G A;  4QAP A;  3RO1 A;  3QKP A;  3D1Q A;  4QBE A;  3QCM A;  1X24 A;  2F71 A;  2QEP A;  2CMA A;  3MMJ A;  1YWF A;  1G7F A;  2GJT A;  2I75 A;  4WU3 A;  5IBM A;  4R0S A;  2I3U A;  4OHD A;  3A5J A;  2M3V A;  3ZV2 A;  5KAA A;  1P15 A;  5MMZ B;  1WCH A;  1T4J A;  3N0A A;  4ICZ A;  1XRI A;  5IBS A;  3CWE A;  3QCN A;  2CJZ A;  1KAK A;  2B4O A;  3EB1 A;  1LYV A;  2CNE A;  4ERC A;  2PT0 A;  4RDD A;  3F9A A;  2B07 A;  4NWF A;  4OHH A;  1WAX A;  1YTW A;  4NYH A;  2P4D A;  4RH9 A;  2B4P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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