1AAXA

Crystal structure of protein tyrosine phosphatase 1b complexed with two bis(para-phosphophenyl)methane (bppm) molecules
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHSSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN TYROSINE PHOSPHATASE 1B
total genus 110
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 1997-01-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1aaxA00
2I6PA 2Q05A 2GP0A 1LARA 2C7SA 1T48A 3O4UA 2HC1A 5KACA 1I57A 1YTNA 2HB1A 3QKQA 1OHDA 1I9SA 1ZC0A 1RPMA 4GFVA 2H04A 5IBSA 2QDPA 4QBWA 1NZ7A 2BV5A 2WGPA 3AWGA 3O5XA 1KAVA 5GTJA 2F6VA 1G4WR 3A5JA 1PTYA 5BX1A 2JJDA 4NWGA 2PQ5A 2CNEA 3QCJA 1NL9A 3ZMPA 1YTWA 2B4OA 3D42A 2A8BA 3O3LA 2VEYA 4J51A 3QCLA 1C88A 1C85A 3D9CA 3F99A 4YAAA 2B4UA 3V0DA 1R6HA 1MKPA 1X24A 3GXHA 2CM8A 1ONYA 4QAPA 4RKKA 2B07A 3AWEA 1PTTA 2CNIA 3EB1A 4HJPA 3ZM0A 5KA0A 3QCDA 3N0AA 2CMAA 2HVLA 2I4GA 2HC2A 2QBRA 2CJZA 4GRZA 2VEXA 4D3QA 2NTAA 2C46A 2ESBA 5LXQB 3M4UA 3QCCA 1FQ1A 2F71A 4OHIA 1PTUA 1L8GA 2B4PA 1C83A 1LYVA 4RI5A 4GE6A 3QCKA 2J16A 2I4EA 4H1OA 3SR9A 5BUGA 2OOQA 3ZMQA 4BPCA 5AWXA 1OEUA 2I6IA 2R0BA 4OHHA 2BIJA 3S3HA 1RXDA 4ICZA 1G1GA 1NWEA 1QXKA 3LJ8A 4YR8B 3BLUA 1G1HA 3EZZA 3QCIA 4Y14A 5KADA 3D1QA 3O4SA 2H03A 5J8RA 4R0TA 1NNYA 4PVGA 2I42A 1ZZWA 2F46A 2ZMMA 4S0GA 4AZ1A 5BZXA 3I36A 2SHPA 1JLNA 1WCHA 1YFOA 2FH7A 2NZ6A 3V0GA 4I8NA 4DGXA 2DXPA 4IKCA 1YGRA 2BZLA 1JF7A 4NX8A 3D1OA 1YTSA 1ZCLA 1LQFA 3F9AA 1OEOX 1FPRA 1YN9A 1SUGA 5KA1A 2B49A 2HNQA 1XM2A 2QCJA 3QCGA 1T4JA 2Y2FA 4NWFA 5K9WA 2F6FA 3EMUA 4KYRA 2OC3A 4KYQA 1KAKA 2F6WA 5K9VA 2CM2A 2E0TA 4ERCA 2I6MA 4GWFA 2H4KA 2H4VA 2QEPA 2ZN7A 1Q6JA 2I1YA 3V0FA 3ZM3A 2CMBA 2VEWA 1OHEA 2GJTA 1G7FA 2PA5A 4NNDA 3S3KA 1C87A 1ZCKA 2G6ZA 2FJMA 2I6JA 4QUMA 1L8KA 2RF6A 3MOWA 4OHEA 3RZ2A 3A5KA 2OUDA 2I75A 3B7OA 3SMEA 4JMJA 3PS5A 2CNGA 3V0EA 4H34A 4HJQA 3QCNA 4QUNA 4GE2A 5K25A 1Q1MA 4JNBA 3BLTA 1BZCA 1AAXA 1QZ0A 4HRFA 4WOHA 4WU2A 4WTYA 1PTVA 1Q6SA 2CFVA 3RO1A 3EU0A 1OESA 2HY3A 1Q6NA 1PYNA 3NMEA 2FJNA 4BJOA 1ONZA 2H02A 2B4SA 4JBCA 1G4US 3ZV2A 3V0IA 4OHLA 1EENA 3EAXA 1G1FA 2F6YA 2J16B 5KAAA 5KA4A 1PA1A 2CM3A 3MOZA 5I6VA 1GWZA 5KA3A 3BM8A 3V0HA 3I7ZA 1OETA 2OZ5A 4ZI4A 3S4EA 3F81A 4Y2EA 3QCFA 3QCBA 2Y96A 4ZN5A 3S4OA 4RHGA 3BRHA 2QBQA 2QCTA 5BZZA 3D44A 4KI9A 5KA2A 2G59A 2GWOA 1YPTA 2I3RA 2CNHA 2I5XA 4DGPA 3I80A 3V0JA 2QDCA 1D5RA 3D1HA 2MBCA 1PA9A 1VHRA 1Q6TA 2PT0A 1I9TA 2NT7A 2VEUA 2QDMA 3S3EA 4GRYA 1EEOA 5IBMA 1U24A 2I3UA 2NLKA 1A5YA 1WRMA 4NYHA 1NO6A 1C84A 1T49A 4ZRTA 4RI4A 1J4XA 1G7GA 1M3GA 4GFUA 3S3FA 2CMCA 3RGQA 2F6TA 5M43A 3F41A 1P15A 1YZ4A 5MMZB 1YGUA 4RH9A 5K22A 2H4GA 4D3RA 2HNPA 4Z6BA 1ECVA 4QBEA 2QBSA 2HXPA 2P4DA 3OMHA 2QBPA 3AWFA 2I4HA 3QCEA 3H2XA 2M3VA 2PI7A 5EHPA 1OEVA 2VEVA 2BGEA 5K24A 3CWEA 4JMKA 2F70A 2I6OA 5EHRA 5KA7A 1XBOA 1NWLA 2AZRA 4RDDA 5KA9A 5KABA 1WAXA 2CM7A 3OLRA 4R30A 3O4TA 4TVVA 3U96A 2NV5A 4B04A 2CNFA 1Q6PA 2PSZA 1GFYA 1C86A 3ZM1A 5KA8A 2PBNA 1Q6MA 3RGOA 1YWFA 1OEMX 3MMJA 1XRIA 4MBBA 3ZM2A 2Q47A 5HDEA 3GXGA 3F9BA 3QKPA 1U26A 4OHDA 1U25A 2YDUA 1FPZA 2BGDA 4GE5A 3QCMA 2AHSA 2J17A 3CM3A 2P6XA 4R0SA 2F6ZA 1OHCA 1XXVA 2B3OA 4D3PA 2IMGA 4GS0A 1PH0A 2NT2A 4PYHA 2A3KA 4WU3A 1BZJA 1PXHA 5K23A 1XXPA 3QCHA 4RH5A 2HCMA 4QAHA 1V3AA 1BZHA
chains in the Genus database with same CATH superfamily
1GQYA 2I6PA 2Q05A 2GP0A 2WTZA 1LARA 2C7SA 1T48A 3O4UA 2HC1A 5KACA 1I57A 1YTNA 2JFHA 2HB1A 3QKQA 1OHDA 1I9SA 1ZC0A 1RPMA 4GFVA 2H04A 5IBSA 2QDPA 4QBWA 1NZ7A 2BV5A 2WGPA 3AWGA 3O5XA 1KAVA 5GTJA 2F6VA 1G4WR 3A5JA 1PTYA 5BX1A 2JJDA 4NWGA 2PQ5A 2CNEA 3QCJA 1NL9A 3ZMPA 1YTWA 2B4OA 3D42A 2A8BA 3O3LA 2VEYA 4J51A 3QCLA 1C88A 1C85A 3D9CA 3F99A 4YAAA 2B4UA 4BUBA 3V0DA 1R6HA 1MKPA 1X24A 3GXHA 2JFFA 2CM8A 1ONYA 4QAPA 4RKKA 2B07A 3AWEA 1PTTA 2CNIA 3EB1A 4HJPA 3ZM0A 5KA0A 3QCDA 3N0AA 2CMAA 2HVLA 2I4GA 2HC2A 2QBRA 2CJZA 2JFGA 4GRZA 2VEXA 4D3QA 2NTAA 2C46A 3QCZA 2ESBA 5LXQB 3M4UA 3QCCA 1FQ1A 2F71A 4OHIA 1PTUA 1L8GA 2B4PA 1C83A 1LYVA 4RI5A 4GE6A 3QCKA 2J16A 2I4EA 4H1OA 3SR9A 5BUGA 2OOQA 3ZMQA 4BPCA 5AWXA 3MVNA 1OEUA 2I6IA 2R0BA 2Y1OA 4OHHA 2F00A 2BIJA 2GC6A 3S3HA 1RXDA 2GCBA 4ICZA 1G1GA 1NWEA 1QXKA 3LJ8A 4YR8B 3BLUA 1G1HA 3EZZA 3HN7A 3QCIA 2VOSA 4Y14A 5KADA 3D1QA 3O4SA 1E8CA 1W7KA 2H03A 5J8RA 4R0TA 1NNYA 4PVGA 2I42A 1ZZWA 2F46A 2ZMMA 4S0GA 4AZ1A 5BZXA 3ZM5A 3I36A 2SHPA 1JLNA 1WCHA 3N2AA 1YFOA 2FH7A 2NZ6A 3V0GA 2GCAA 4I8NA 4DGXA 2DXPA 4IKCA 1YGRA 2VTDA 2BZLA 1E0DA 1JF7A 1GQQA 4NX8A 3D1OA 1YTSA 1ZCLA 1LQFA 3F9AA 1OEOX 1FPRA 1YN9A 1SUGA 2VTEA 5KA1A 2B49A 2HNQA 1XM2A 3ZL8A 2QCJA 3QCGA 2UUOA 1T4JA 2Y2FA 4NWFA 5K9WA 2F6FA 2GC5A 2Y67A 3UAGA 3EMUA 4KYRA 2OC3A 4KYQA 1KAKA 3PYZA 2F6WA 5K9VA 2CM2A 2E0TA 2VORA 4ERCA 2I6MA 4GWFA 2H4KA 2H4VA 2QEPA 2ZN7A 1Q6JA 2I1YA 3V0FA 3ZM3A 2CMBA 2VEWA 1OHEA 2WJPA 2GJTA 1G7FA 2PA5A 4NNDA 3S3KA 1C87A 1ZCKA 2G6ZA 2FJMA 2I6JA 4QUMA 1L8KA 2RF6A 3MOWA 4OHEA 3RZ2A 3ZM6A 3A5KA 2OUDA 2I75A 3B7OA 3SMEA 4JMJA 3PS5A 2CNGA 3V0EA 4H34A 4HJQA 3QCNA 4QUNA 4GE2A 5K25A 1Q1MA 4JNBA 3BLTA 5A5FA 1BZCA 1AAXA 1QZ0A 4HRFA 4WOHA 4WU2A 4WTYA 1PTVA 1JBWA 1Q6SA 2CFVA 3RO1A 3EU0A 1OESA 2HY3A 1Q6NA 1PYNA 3NMEA 1EEHA 1W78A 2FJNA 4BJOA 1ONZA 2H02A 2B4SA 4JBCA 1G4US 3ZV2A 3V0IA 4OHLA 1EENA 3EAXA 1G1FA 2F6YA 2J16B 5KAAA 5KA4A 1PA1A 2CM3A 2Y68A 3MOZA 5I6VA 3LK7A 1GWZA 5KA3A 2XJAA 3BM8A 3V0HA 3I7ZA 1OETA 2OZ5A 4ZI4A 3S4EA 3F81A 4Y2EA 2UUPA 3QCFA 3QCBA 2AM1A 2Y96A 4ZN5A 3S4OA 4RHGA 3BRHA 2QBQA 2QCTA 5BZZA 2X5OA 3D44A 4KI9A 5KA2A 4ZIYA 2XPCA 2G59A 2GWOA 1YPTA 2I3RA 2CNHA 2I5XA 4CVLA 4DGPA 1GG4A 4QF5A 3I80A 4BUCA 3V0JA 2QDCA 1D5RA 4HV4A 3D1HA 2MBCA 1PA9A 1VHRA 1P31A 1Q6TA 4CVMA 2PT0A 1I9TA 2NT7A 2VEUA 2QDMA 1JBVA 3S3EA 1FGSA 4GRYA 1EEOA 5IBMA 1U24A 2I3UA 2NLKA 1A5YA 1WRMA 4NYHA 1NO6A 1C84A 1T49A 4ZRTA 4RI4A 1J4XA 1G7GA 1M3GA 4GFUA 3S3FA 1J6UA 2CMCA 3RGQA 2F6TA 5M43A 3F41A 2Y66A 1P15A 1YZ4A 5MMZB 1YGUA 4RH9A 5K22A 2H4GA 4D3RA 2HNPA 4Z6BA 1ECVA 4QDIA 4QBEA 2QBSA 2HXPA 2P4DA 3OMHA 2QBPA 3AWFA 2I4HA 3QCEA 4C13A 3H2XA 2M3VA 2PI7A 5EHPA 1OEVA 2VEVA 2AM2A 2BGEA 5K24A 3CWEA 4JMKA 1UAGA 2F70A 2I6OA 3NRSA 5EHRA 5KA7A 1XBOA 1NWLA 2AZRA 1O5ZA 4RDDA 5KA9A 5KABA 1WAXA 2CM7A 3OLRA 4R30A 3O4TA 4TVVA 1P3DA 3U96A 2NV5A 4B04A 2CNFA 1Q6PA 2PSZA 1GFYA 1C86A 3ZM1A 4UAGA 5KA8A 2PBNA 1Q6MA 3RGOA 1YWFA 1OEMX 3MMJA 1XRIA 4MBBA 3ZM2A 2Q47A 5HDEA 3GXGA 3F9BA 3QKPA 2UAGA 1U26A 4OHDA 1U25A 2YDUA 1FPZA 2BGDA 4GE5A 3QCMA 2AHSA 2J17A 3CM3A 2P6XA 4R0SA 5A5EA 2F6ZA 1OHCA 1XXVA 2B3OA 4D3PA 2IMGA 4GS0A 4CVKA 1PH0A 2NT2A 4PYHA 2A3KA 4WU3A 1BZJA 4C12A 1PXHA 5K23A 1XXPA 3QCHA 4RH5A 2HCMA 4QAHA 1V3AA 1BZHA
chains in the Genus database with same CATH topology
2I6PA 2Q05A 2GP0A 1LARA 2C7SA 1T48A 3O4UA 2HC1A 5KACA 1I57A 1YTNA 2HB1A 3QKQA 1OHDA 1I9SA 1ZC0A 1RPMA 4GFVA 2H04A 5IBSA 2QDPA 4QBWA 1NZ7A 2BV5A 2WGPA 3AWGA 3O5XA 1KAVA 5GTJA 2F6VA 1G4WR 3A5JA 1PTYA 5BX1A 2JJDA 4NWGA 2PQ5A 2CNEA 3QCJA 1NL9A 3ZMPA 1YTWA 2B4OA 3D42A 2A8BA 3O3LA 2VEYA 4J51A 3QCLA 1C88A 1C85A 3D9CA 3F99A 4YAAA 2B4UA 3V0DA 1R6HA 1MKPA 1X24A 3GXHA 2CM8A 1ONYA 4QAPA 4RKKA 2B07A 3AWEA 1PTTA 2CNIA 3EB1A 4HJPA 3ZM0A 5KA0A 3QCDA 3N0AA 2CMAA 2HVLA 2I4GA 2HC2A 2QBRA 2CJZA 4GRZA 2VEXA 4D3QA 2NTAA 2C46A 2ESBA 5LXQB 3M4UA 3QCCA 1FQ1A 2F71A 4OHIA 1PTUA 1L8GA 2B4PA 1C83A 1LYVA 4RI5A 4GE6A 3QCKA 2J16A 2I4EA 4H1OA 3SR9A 5BUGA 2OOQA 3ZMQA 4BPCA 5AWXA 1OEUA 2I6IA 2R0BA 4OHHA 2BIJA 3S3HA 1RXDA 4ICZA 1G1GA 1NWEA 1QXKA 3LJ8A 4YR8B 3BLUA 1G1HA 3EZZA 3QCIA 4Y14A 5KADA 3D1QA 3O4SA 2H03A 5J8RA 4R0TA 1NNYA 4PVGA 2I42A 1ZZWA 2F46A 2ZMMA 4S0GA 4AZ1A 5BZXA 3I36A 2SHPA 1JLNA 1WCHA 1YFOA 2FH7A 2NZ6A 3V0GA 4I8NA 4DGXA 2DXPA 4IKCA 1YGRA 2BZLA 1JF7A 4NX8A 3D1OA 1YTSA 1ZCLA 1LQFA 3F9AA 1OEOX 1FPRA 1YN9A 1SUGA 5KA1A 2B49A 2HNQA 1XM2A 2QCJA 3QCGA 1T4JA 2Y2FA 4NWFA 5K9WA 2F6FA 3EMUA 4KYRA 2OC3A 4KYQA 1KAKA 2F6WA 5K9VA 2CM2A 2E0TA 4ERCA 2I6MA 4GWFA 2H4KA 2H4VA 2QEPA 2ZN7A 1Q6JA 2I1YA 3V0FA 3ZM3A 2CMBA 2VEWA 1OHEA 2GJTA 1G7FA 2PA5A 4NNDA 3S3KA 1C87A 1ZCKA 2G6ZA 2FJMA 2I6JA 4QUMA 1L8KA 2RF6A 3MOWA 4OHEA 3RZ2A 3A5KA 2OUDA 2I75A 3B7OA 3SMEA 4JMJA 3PS5A 2CNGA 3V0EA 4H34A 4HJQA 3QCNA 4QUNA 4GE2A 5K25A 1Q1MA 4JNBA 3BLTA 1BZCA 1AAXA 1QZ0A 4HRFA 4WOHA 4WU2A 4WTYA 1PTVA 1Q6SA 2CFVA 3RO1A 3EU0A 1OESA 2HY3A 1Q6NA 1PYNA 3NMEA 2FJNA 4BJOA 1ONZA 2H02A 2B4SA 4JBCA 1G4US 3ZV2A 3V0IA 4OHLA 1EENA 3EAXA 1G1FA 2F6YA 2J16B 5KAAA 5KA4A 1PA1A 2CM3A 3MOZA 5I6VA 1GWZA 5KA3A 3BM8A 3V0HA 3I7ZA 1OETA 2OZ5A 4ZI4A 3S4EA 3F81A 4Y2EA 3QCFA 3QCBA 2Y96A 4ZN5A 3S4OA 4RHGA 3BRHA 2QBQA 2QCTA 5BZZA 3D44A 4KI9A 5KA2A 2G59A 2GWOA 1YPTA 2I3RA 2CNHA 2I5XA 4DGPA 3I80A 3V0JA 2QDCA 1D5RA 3D1HA 2MBCA 1PA9A 1VHRA 1Q6TA 2PT0A 1I9TA 2NT7A 2VEUA 2QDMA 3S3EA 4GRYA 1EEOA 5IBMA 1U24A 2I3UA 2NLKA 1A5YA 1WRMA 4NYHA 1NO6A 1C84A 1T49A 4ZRTA 4RI4A 1J4XA 1G7GA 1M3GA 4GFUA 3S3FA 2CMCA 3RGQA 2F6TA 5M43A 3F41A 1P15A 1YZ4A 5MMZB 1YGUA 4RH9A 5K22A 2H4GA 4D3RA 2HNPA 4Z6BA 1ECVA 4QBEA 2QBSA 2HXPA 2P4DA 3OMHA 2QBPA 3AWFA 2I4HA 3QCEA 3H2XA 2M3VA 2PI7A 5EHPA 1OEVA 2VEVA 2BGEA 5K24A 3CWEA 4JMKA 2F70A 2I6OA 5EHRA 5KA7A 1XBOA 1NWLA 2AZRA 4RDDA 5KA9A 5KABA 1WAXA 2CM7A 3OLRA 4R30A 3O4TA 4TVVA 3U96A 2NV5A 4B04A 2CNFA 1Q6PA 2PSZA 1GFYA 1C86A 3ZM1A 5KA8A 2PBNA 1Q6MA 3RGOA 1YWFA 1OEMX 3MMJA 1XRIA 4MBBA 3ZM2A 2Q47A 5HDEA 3GXGA 3F9BA 3QKPA 1U26A 4OHDA 1U25A 2YDUA 1FPZA 2BGDA 4GE5A 3QCMA 2AHSA 2J17A 3CM3A 2P6XA 4R0SA 2F6ZA 1OHCA 1XXVA 2B3OA 4D3PA 2IMGA 4GS0A 1PH0A 2NT2A 4PYHA 2A3KA 4WU3A 1BZJA 1PXHA 5K23A 1XXPA 3QCHA 4RH5A 2HCMA 4QAHA 1V3AA 1BZHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I6P A;  2Q05 A;  2GP0 A;  1LAR A;  2C7S A;  1T48 A;  3O4U A;  2HC1 A;  5KAC A;  1I57 A;  1YTN A;  2HB1 A;  3QKQ A;  1OHD A;  1I9S A;  1ZC0 A;  1RPM A;  4GFV A;  2H04 A;  5IBS A;  2QDP A;  4QBW A;  1NZ7 A;  2BV5 A;  2WGP A;  3AWG A;  3O5X A;  1KAV A;  5GTJ A;  2F6V A;  1G4W R;  3A5J A;  1PTY A;  5BX1 A;  2JJD A;  4NWG A;  2PQ5 A;  2CNE A;  3QCJ A;  1NL9 A;  3ZMP A;  1YTW A;  2B4O A;  3D42 A;  2A8B A;  3O3L A;  2VEY A;  4J51 A;  3QCL A;  1C88 A;  1C85 A;  3D9C A;  3F99 A;  4YAA A;  2B4U A;  3V0D A;  1R6H A;  1MKP A;  1X24 A;  3GXH A;  2CM8 A;  1ONY A;  4QAP A;  4RKK A;  2B07 A;  3AWE A;  1PTT A;  2CNI A;  3EB1 A;  4HJP A;  3ZM0 A;  5KA0 A;  3QCD A;  3N0A A;  2CMA A;  2HVL A;  2I4G A;  2HC2 A;  2QBR A;  2CJZ A;  4GRZ A;  2VEX A;  4D3Q A;  2NTA A;  2C46 A;  2ESB A;  5LXQ B;  3M4U A;  3QCC A;  1FQ1 A;  2F71 A;  4OHI A;  1PTU A;  1L8G A;  2B4P A;  1C83 A;  1LYV A;  4RI5 A;  4GE6 A;  3QCK A;  2J16 A;  2I4E A;  4H1O A;  3SR9 A;  5BUG A;  2OOQ A;  3ZMQ A;  4BPC A;  5AWX A;  1OEU A;  2I6I A;  2R0B A;  4OHH A;  2BIJ A;  3S3H A;  1RXD A;  4ICZ A;  1G1G A;  1NWE A;  1QXK A;  3LJ8 A;  4YR8 B;  3BLU A;  1G1H A;  3EZZ A;  3QCI A;  4Y14 A;  5KAD A;  3D1Q A;  3O4S A;  2H03 A;  5J8R A;  4R0T A;  1NNY A;  4PVG A;  2I42 A;  1ZZW A;  2F46 A;  2ZMM A;  4S0G A;  4AZ1 A;  5BZX A;  3I36 A;  2SHP A;  1JLN A;  1WCH A;  1YFO A;  2FH7 A;  2NZ6 A;  3V0G A;  4I8N A;  4DGX A;  2DXP A;  4IKC A;  1YGR A;  2BZL A;  1JF7 A;  4NX8 A;  3D1O A;  1YTS A;  1ZCL A;  1LQF A;  3F9A A;  1OEO X;  1FPR A;  1YN9 A;  1SUG A;  5KA1 A;  2B49 A;  2HNQ A;  1XM2 A;  2QCJ A;  3QCG A;  1T4J A;  2Y2F A;  4NWF A;  5K9W A;  2F6F A;  3EMU A;  4KYR A;  2OC3 A;  4KYQ A;  1KAK A;  2F6W A;  5K9V A;  2CM2 A;  2E0T A;  4ERC A;  2I6M A;  4GWF A;  2H4K A;  2H4V A;  2QEP A;  2ZN7 A;  1Q6J A;  2I1Y A;  3V0F A;  3ZM3 A;  2CMB A;  2VEW A;  1OHE A;  2GJT A;  1G7F A;  2PA5 A;  4NND A;  3S3K A;  1C87 A;  1ZCK A;  2G6Z A;  2FJM A;  2I6J A;  4QUM A;  1L8K A;  2RF6 A;  3MOW A;  4OHE A;  3RZ2 A;  3A5K A;  2OUD A;  2I75 A;  3B7O A;  3SME A;  4JMJ A;  3PS5 A;  2CNG A;  3V0E A;  4H34 A;  4HJQ A;  3QCN A;  4QUN A;  4GE2 A;  5K25 A;  1Q1M A;  4JNB A;  3BLT A;  1BZC A;  1AAX A;  1QZ0 A;  4HRF A;  4WOH A;  4WU2 A;  4WTY A;  1PTV A;  1Q6S A;  2CFV A;  3RO1 A;  3EU0 A;  1OES A;  2HY3 A;  1Q6N A;  1PYN A;  3NME A;  2FJN A;  4BJO A;  1ONZ A;  2H02 A;  2B4S A;  4JBC A;  1G4U S;  3ZV2 A;  3V0I A;  4OHL A;  1EEN A;  3EAX A;  1G1F A;  2F6Y A;  2J16 B;  5KAA A;  5KA4 A;  1PA1 A;  2CM3 A;  3MOZ A;  5I6V A;  1GWZ A;  5KA3 A;  3BM8 A;  3V0H A;  3I7Z A;  1OET A;  2OZ5 A;  4ZI4 A;  3S4E A;  3F81 A;  4Y2E A;  3QCF A;  3QCB A;  2Y96 A;  4ZN5 A;  3S4O A;  4RHG A;  3BRH A;  2QBQ A;  2QCT A;  5BZZ A;  3D44 A;  4KI9 A;  5KA2 A;  2G59 A;  2GWO A;  1YPT A;  2I3R A;  2CNH A;  2I5X A;  4DGP A;  3I80 A;  3V0J A;  2QDC A;  1D5R A;  3D1H A;  2MBC A;  1PA9 A;  1VHR A;  1Q6T A;  2PT0 A;  1I9T A;  2NT7 A;  2VEU A;  2QDM A;  3S3E A;  4GRY A;  1EEO A;  5IBM A;  1U24 A;  2I3U A;  2NLK A;  1A5Y A;  1WRM A;  4NYH A;  1NO6 A;  1C84 A;  1T49 A;  4ZRT A;  4RI4 A;  1J4X A;  1G7G A;  1M3G A;  4GFU A;  3S3F A;  2CMC A;  3RGQ A;  2F6T A;  5M43 A;  3F41 A;  1P15 A;  1YZ4 A;  5MMZ B;  1YGU A;  4RH9 A;  5K22 A;  2H4G A;  4D3R A;  2HNP A;  4Z6B A;  1ECV A;  4QBE A;  2QBS A;  2HXP A;  2P4D A;  3OMH A;  2QBP A;  3AWF A;  2I4H A;  3QCE A;  3H2X A;  2M3V A;  2PI7 A;  5EHP A;  1OEV A;  2VEV A;  2BGE A;  5K24 A;  3CWE A;  4JMK A;  2F70 A;  2I6O A;  5EHR A;  5KA7 A;  1XBO A;  1NWL A;  2AZR A;  4RDD A;  5KA9 A;  5KAB A;  1WAX A;  2CM7 A;  3OLR A;  4R30 A;  3O4T A;  4TVV A;  3U96 A;  2NV5 A;  4B04 A;  2CNF A;  1Q6P A;  2PSZ A;  1GFY A;  1C86 A;  3ZM1 A;  5KA8 A;  2PBN A;  1Q6M A;  3RGO A;  1YWF A;  1OEM X;  3MMJ A;  1XRI A;  4MBB A;  3ZM2 A;  2Q47 A;  5HDE A;  3GXG A;  3F9B A;  3QKP A;  1U26 A;  4OHD A;  1U25 A;  2YDU A;  1FPZ A;  2BGD A;  4GE5 A;  3QCM A;  2AHS A;  2J17 A;  3CM3 A;  2P6X A;  4R0S A;  2F6Z A;  1OHC A;  1XXV A;  2B3O A;  4D3P A;  2IMG A;  4GS0 A;  1PH0 A;  2NT2 A;  4PYH A;  2A3K A;  4WU3 A;  1BZJ A;  1PXH A;  5K23 A;  1XXP A;  3QCH A;  4RH5 A;  2HCM A;  4QAH A;  1V3A A;  1BZH A; 
#chains in the Genus database with same CATH topology
 1GQY A;  2I6P A;  2Q05 A;  2GP0 A;  2WTZ A;  1LAR A;  2C7S A;  1T48 A;  3O4U A;  2HC1 A;  5KAC A;  1I57 A;  1YTN A;  2JFH A;  2HB1 A;  3QKQ A;  1OHD A;  1I9S A;  1ZC0 A;  1RPM A;  4GFV A;  2H04 A;  5IBS A;  2QDP A;  4QBW A;  1NZ7 A;  2BV5 A;  2WGP A;  3AWG A;  3O5X A;  1KAV A;  5GTJ A;  2F6V A;  1G4W R;  3A5J A;  1PTY A;  5BX1 A;  2JJD A;  4NWG A;  2PQ5 A;  2CNE A;  3QCJ A;  1NL9 A;  3ZMP A;  1YTW A;  2B4O A;  3D42 A;  2A8B A;  3O3L A;  2VEY A;  4J51 A;  3QCL A;  1C88 A;  1C85 A;  3D9C A;  3F99 A;  4YAA A;  2B4U A;  4BUB A;  3V0D A;  1R6H A;  1MKP A;  1X24 A;  3GXH A;  2JFF A;  2CM8 A;  1ONY A;  4QAP A;  4RKK A;  2B07 A;  3AWE A;  1PTT A;  2CNI A;  3EB1 A;  4HJP A;  3ZM0 A;  5KA0 A;  3QCD A;  3N0A A;  2CMA A;  2HVL A;  2I4G A;  2HC2 A;  2QBR A;  2CJZ A;  2JFG A;  4GRZ A;  2VEX A;  4D3Q A;  2NTA A;  2C46 A;  3QCZ A;  2ESB A;  5LXQ B;  3M4U A;  3QCC A;  1FQ1 A;  2F71 A;  4OHI A;  1PTU A;  1L8G A;  2B4P A;  1C83 A;  1LYV A;  4RI5 A;  4GE6 A;  3QCK A;  2J16 A;  2I4E A;  4H1O A;  3SR9 A;  5BUG A;  2OOQ A;  3ZMQ A;  4BPC A;  5AWX A;  3MVN A;  1OEU A;  2I6I A;  2R0B A;  2Y1O A;  4OHH A;  2F00 A;  2BIJ A;  2GC6 A;  3S3H A;  1RXD A;  2GCB A;  4ICZ A;  1G1G A;  1NWE A;  1QXK A;  3LJ8 A;  4YR8 B;  3BLU A;  1G1H A;  3EZZ A;  3HN7 A;  3QCI A;  2VOS A;  4Y14 A;  5KAD A;  3D1Q A;  3O4S A;  1E8C A;  1W7K A;  2H03 A;  5J8R A;  4R0T A;  1NNY A;  4PVG A;  2I42 A;  1ZZW A;  2F46 A;  2ZMM A;  4S0G A;  4AZ1 A;  5BZX A;  3ZM5 A;  3I36 A;  2SHP A;  1JLN A;  1WCH A;  3N2A A;  1YFO A;  2FH7 A;  2NZ6 A;  3V0G A;  2GCA A;  4I8N A;  4DGX A;  2DXP A;  4IKC A;  1YGR A;  2VTD A;  2BZL A;  1E0D A;  1JF7 A;  1GQQ A;  4NX8 A;  3D1O A;  1YTS A;  1ZCL A;  1LQF A;  3F9A A;  1OEO X;  1FPR A;  1YN9 A;  1SUG A;  2VTE A;  5KA1 A;  2B49 A;  2HNQ A;  1XM2 A;  3ZL8 A;  2QCJ A;  3QCG A;  2UUO A;  1T4J A;  2Y2F A;  4NWF A;  5K9W A;  2F6F A;  2GC5 A;  2Y67 A;  3UAG A;  3EMU A;  4KYR A;  2OC3 A;  4KYQ A;  1KAK A;  3PYZ A;  2F6W A;  5K9V A;  2CM2 A;  2E0T A;  2VOR A;  4ERC A;  2I6M A;  4GWF A;  2H4K A;  2H4V A;  2QEP A;  2ZN7 A;  1Q6J A;  2I1Y A;  3V0F A;  3ZM3 A;  2CMB A;  2VEW A;  1OHE A;  2WJP A;  2GJT A;  1G7F A;  2PA5 A;  4NND A;  3S3K A;  1C87 A;  1ZCK A;  2G6Z A;  2FJM A;  2I6J A;  4QUM A;  1L8K A;  2RF6 A;  3MOW A;  4OHE A;  3RZ2 A;  3ZM6 A;  3A5K A;  2OUD A;  2I75 A;  3B7O A;  3SME A;  4JMJ A;  3PS5 A;  2CNG A;  3V0E A;  4H34 A;  4HJQ A;  3QCN A;  4QUN A;  4GE2 A;  5K25 A;  1Q1M A;  4JNB A;  3BLT A;  5A5F A;  1BZC A;  1AAX A;  1QZ0 A;  4HRF A;  4WOH A;  4WU2 A;  4WTY A;  1PTV A;  1JBW A;  1Q6S A;  2CFV A;  3RO1 A;  3EU0 A;  1OES A;  2HY3 A;  1Q6N A;  1PYN A;  3NME A;  1EEH A;  1W78 A;  2FJN A;  4BJO A;  1ONZ A;  2H02 A;  2B4S A;  4JBC A;  1G4U S;  3ZV2 A;  3V0I A;  4OHL A;  1EEN A;  3EAX A;  1G1F A;  2F6Y A;  2J16 B;  5KAA A;  5KA4 A;  1PA1 A;  2CM3 A;  2Y68 A;  3MOZ A;  5I6V A;  3LK7 A;  1GWZ A;  5KA3 A;  2XJA A;  3BM8 A;  3V0H A;  3I7Z A;  1OET A;  2OZ5 A;  4ZI4 A;  3S4E A;  3F81 A;  4Y2E A;  2UUP A;  3QCF A;  3QCB A;  2AM1 A;  2Y96 A;  4ZN5 A;  3S4O A;  4RHG A;  3BRH A;  2QBQ A;  2QCT A;  5BZZ A;  2X5O A;  3D44 A;  4KI9 A;  5KA2 A;  4ZIY A;  2XPC A;  2G59 A;  2GWO A;  1YPT A;  2I3R A;  2CNH A;  2I5X A;  4CVL A;  4DGP A;  1GG4 A;  4QF5 A;  3I80 A;  4BUC A;  3V0J A;  2QDC A;  1D5R A;  4HV4 A;  3D1H A;  2MBC A;  1PA9 A;  1VHR A;  1P31 A;  1Q6T A;  4CVM A;  2PT0 A;  1I9T A;  2NT7 A;  2VEU A;  2QDM A;  1JBV A;  3S3E A;  1FGS A;  4GRY A;  1EEO A;  5IBM A;  1U24 A;  2I3U A;  2NLK A;  1A5Y A;  1WRM A;  4NYH A;  1NO6 A;  1C84 A;  1T49 A;  4ZRT A;  4RI4 A;  1J4X A;  1G7G A;  1M3G A;  4GFU A;  3S3F A;  1J6U A;  2CMC A;  3RGQ A;  2F6T A;  5M43 A;  3F41 A;  2Y66 A;  1P15 A;  1YZ4 A;  5MMZ B;  1YGU A;  4RH9 A;  5K22 A;  2H4G A;  4D3R A;  2HNP A;  4Z6B A;  1ECV A;  4QDI A;  4QBE A;  2QBS A;  2HXP A;  2P4D A;  3OMH A;  2QBP A;  3AWF A;  2I4H A;  3QCE A;  4C13 A;  3H2X A;  2M3V A;  2PI7 A;  5EHP A;  1OEV A;  2VEV A;  2AM2 A;  2BGE A;  5K24 A;  3CWE A;  4JMK A;  1UAG A;  2F70 A;  2I6O A;  3NRS A;  5EHR A;  5KA7 A;  1XBO A;  1NWL A;  2AZR A;  1O5Z A;  4RDD A;  5KA9 A;  5KAB A;  1WAX A;  2CM7 A;  3OLR A;  4R30 A;  3O4T A;  4TVV A;  1P3D A;  3U96 A;  2NV5 A;  4B04 A;  2CNF A;  1Q6P A;  2PSZ A;  1GFY A;  1C86 A;  3ZM1 A;  4UAG A;  5KA8 A;  2PBN A;  1Q6M A;  3RGO A;  1YWF A;  1OEM X;  3MMJ A;  1XRI A;  4MBB A;  3ZM2 A;  2Q47 A;  5HDE A;  3GXG A;  3F9B A;  3QKP A;  2UAG A;  1U26 A;  4OHD A;  1U25 A;  2YDU A;  1FPZ A;  2BGD A;  4GE5 A;  3QCM A;  2AHS A;  2J17 A;  3CM3 A;  2P6X A;  4R0S A;  5A5E A;  2F6Z A;  1OHC A;  1XXV A;  2B3O A;  4D3P A;  2IMG A;  4GS0 A;  4CVK A;  1PH0 A;  2NT2 A;  4PYH A;  2A3K A;  4WU3 A;  1BZJ A;  4C12 A;  1PXH A;  5K23 A;  1XXP A;  3QCH A;  4RH5 A;  2HCM A;  4QAH A;  1V3A A;  1BZH A; 
#chains in the Genus database with same CATH homology
 2I6P A;  2Q05 A;  2GP0 A;  1LAR A;  2C7S A;  1T48 A;  3O4U A;  2HC1 A;  5KAC A;  1I57 A;  1YTN A;  2HB1 A;  3QKQ A;  1OHD A;  1I9S A;  1ZC0 A;  1RPM A;  4GFV A;  2H04 A;  5IBS A;  2QDP A;  4QBW A;  1NZ7 A;  2BV5 A;  2WGP A;  3AWG A;  3O5X A;  1KAV A;  5GTJ A;  2F6V A;  1G4W R;  3A5J A;  1PTY A;  5BX1 A;  2JJD A;  4NWG A;  2PQ5 A;  2CNE A;  3QCJ A;  1NL9 A;  3ZMP A;  1YTW A;  2B4O A;  3D42 A;  2A8B A;  3O3L A;  2VEY A;  4J51 A;  3QCL A;  1C88 A;  1C85 A;  3D9C A;  3F99 A;  4YAA A;  2B4U A;  3V0D A;  1R6H A;  1MKP A;  1X24 A;  3GXH A;  2CM8 A;  1ONY A;  4QAP A;  4RKK A;  2B07 A;  3AWE A;  1PTT A;  2CNI A;  3EB1 A;  4HJP A;  3ZM0 A;  5KA0 A;  3QCD A;  3N0A A;  2CMA A;  2HVL A;  2I4G A;  2HC2 A;  2QBR A;  2CJZ A;  4GRZ A;  2VEX A;  4D3Q A;  2NTA A;  2C46 A;  2ESB A;  5LXQ B;  3M4U A;  3QCC A;  1FQ1 A;  2F71 A;  4OHI A;  1PTU A;  1L8G A;  2B4P A;  1C83 A;  1LYV A;  4RI5 A;  4GE6 A;  3QCK A;  2J16 A;  2I4E A;  4H1O A;  3SR9 A;  5BUG A;  2OOQ A;  3ZMQ A;  4BPC A;  5AWX A;  1OEU A;  2I6I A;  2R0B A;  4OHH A;  2BIJ A;  3S3H A;  1RXD A;  4ICZ A;  1G1G A;  1NWE A;  1QXK A;  3LJ8 A;  4YR8 B;  3BLU A;  1G1H A;  3EZZ A;  3QCI A;  4Y14 A;  5KAD A;  3D1Q A;  3O4S A;  2H03 A;  5J8R A;  4R0T A;  1NNY A;  4PVG A;  2I42 A;  1ZZW A;  2F46 A;  2ZMM A;  4S0G A;  4AZ1 A;  5BZX A;  3I36 A;  2SHP A;  1JLN A;  1WCH A;  1YFO A;  2FH7 A;  2NZ6 A;  3V0G A;  4I8N A;  4DGX A;  2DXP A;  4IKC A;  1YGR A;  2BZL A;  1JF7 A;  4NX8 A;  3D1O A;  1YTS A;  1ZCL A;  1LQF A;  3F9A A;  1OEO X;  1FPR A;  1YN9 A;  1SUG A;  5KA1 A;  2B49 A;  2HNQ A;  1XM2 A;  2QCJ A;  3QCG A;  1T4J A;  2Y2F A;  4NWF A;  5K9W A;  2F6F A;  3EMU A;  4KYR A;  2OC3 A;  4KYQ A;  1KAK A;  2F6W A;  5K9V A;  2CM2 A;  2E0T A;  4ERC A;  2I6M A;  4GWF A;  2H4K A;  2H4V A;  2QEP A;  2ZN7 A;  1Q6J A;  2I1Y A;  3V0F A;  3ZM3 A;  2CMB A;  2VEW A;  1OHE A;  2GJT A;  1G7F A;  2PA5 A;  4NND A;  3S3K A;  1C87 A;  1ZCK A;  2G6Z A;  2FJM A;  2I6J A;  4QUM A;  1L8K A;  2RF6 A;  3MOW A;  4OHE A;  3RZ2 A;  3A5K A;  2OUD A;  2I75 A;  3B7O A;  3SME A;  4JMJ A;  3PS5 A;  2CNG A;  3V0E A;  4H34 A;  4HJQ A;  3QCN A;  4QUN A;  4GE2 A;  5K25 A;  1Q1M A;  4JNB A;  3BLT A;  1BZC A;  1AAX A;  1QZ0 A;  4HRF A;  4WOH A;  4WU2 A;  4WTY A;  1PTV A;  1Q6S A;  2CFV A;  3RO1 A;  3EU0 A;  1OES A;  2HY3 A;  1Q6N A;  1PYN A;  3NME A;  2FJN A;  4BJO A;  1ONZ A;  2H02 A;  2B4S A;  4JBC A;  1G4U S;  3ZV2 A;  3V0I A;  4OHL A;  1EEN A;  3EAX A;  1G1F A;  2F6Y A;  2J16 B;  5KAA A;  5KA4 A;  1PA1 A;  2CM3 A;  3MOZ A;  5I6V A;  1GWZ A;  5KA3 A;  3BM8 A;  3V0H A;  3I7Z A;  1OET A;  2OZ5 A;  4ZI4 A;  3S4E A;  3F81 A;  4Y2E A;  3QCF A;  3QCB A;  2Y96 A;  4ZN5 A;  3S4O A;  4RHG A;  3BRH A;  2QBQ A;  2QCT A;  5BZZ A;  3D44 A;  4KI9 A;  5KA2 A;  2G59 A;  2GWO A;  1YPT A;  2I3R A;  2CNH A;  2I5X A;  4DGP A;  3I80 A;  3V0J A;  2QDC A;  1D5R A;  3D1H A;  2MBC A;  1PA9 A;  1VHR A;  1Q6T A;  2PT0 A;  1I9T A;  2NT7 A;  2VEU A;  2QDM A;  3S3E A;  4GRY A;  1EEO A;  5IBM A;  1U24 A;  2I3U A;  2NLK A;  1A5Y A;  1WRM A;  4NYH A;  1NO6 A;  1C84 A;  1T49 A;  4ZRT A;  4RI4 A;  1J4X A;  1G7G A;  1M3G A;  4GFU A;  3S3F A;  2CMC A;  3RGQ A;  2F6T A;  5M43 A;  3F41 A;  1P15 A;  1YZ4 A;  5MMZ B;  1YGU A;  4RH9 A;  5K22 A;  2H4G A;  4D3R A;  2HNP A;  4Z6B A;  1ECV A;  4QBE A;  2QBS A;  2HXP A;  2P4D A;  3OMH A;  2QBP A;  3AWF A;  2I4H A;  3QCE A;  3H2X A;  2M3V A;  2PI7 A;  5EHP A;  1OEV A;  2VEV A;  2BGE A;  5K24 A;  3CWE A;  4JMK A;  2F70 A;  2I6O A;  5EHR A;  5KA7 A;  1XBO A;  1NWL A;  2AZR A;  4RDD A;  5KA9 A;  5KAB A;  1WAX A;  2CM7 A;  3OLR A;  4R30 A;  3O4T A;  4TVV A;  3U96 A;  2NV5 A;  4B04 A;  2CNF A;  1Q6P A;  2PSZ A;  1GFY A;  1C86 A;  3ZM1 A;  5KA8 A;  2PBN A;  1Q6M A;  3RGO A;  1YWF A;  1OEM X;  3MMJ A;  1XRI A;  4MBB A;  3ZM2 A;  2Q47 A;  5HDE A;  3GXG A;  3F9B A;  3QKP A;  1U26 A;  4OHD A;  1U25 A;  2YDU A;  1FPZ A;  2BGD A;  4GE5 A;  3QCM A;  2AHS A;  2J17 A;  3CM3 A;  2P6X A;  4R0S A;  2F6Z A;  1OHC A;  1XXV A;  2B3O A;  4D3P A;  2IMG A;  4GS0 A;  1PH0 A;  2NT2 A;  4PYH A;  2A3K A;  4WU3 A;  1BZJ A;  1PXH A;  5K23 A;  1XXP A;  3QCH A;  4RH5 A;  2HCM A;  4QAH A;  1V3A A;  1BZH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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