1C87A

Crystal structure of protein tyrosine phosphatase 1b complexed with 2-(oxalyl-amino-4,7-dihydro-5h-thieno[2,3-c]pyran-3-carboxylic acid
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKTYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLDMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN (PROTEIN-TYROSINE PHOSPHATASE 1B)
total genus 107
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1c87A00
3MMJA 2IMGA 2B4OA 1XXVA 1M3GA 1Q6MA 3CM3A 2GWOA 2HC1A 3ZMQA 2J16B 2GJTA 5KA2A 1YN9A 1FPZA 4I8NA 5IBSA 3S3EA 4PVGA 4NWFA 4H1OA 4ZN5A 5K9WA 1T4JA 4HJQA 1G1GA 2BIJA 2CNGA 2F6WA 3LJ8A 3SR9A 2ESBA 2B4PA 1OHEA 2B49A 2Q47A 1OHDA 2I6MA 1G1HA 4WU3A 2H4KA 3OMHA 2H03A 3D1QA 2I42A 3QKPA 4RH5A 2I6IA 2GP0A 1GFYA 1Q6NA 1J4XA 3S3HA 4KYQA 1FPRA 3NMEA 2QBSA 1L8GA 1XM2A 4HRFA 3OLRA 4QUNA 3QCEA 3ZM3A 3MOWA 1BZJA 3V0IA 1YTNA 2OC3A 2CNHA 4BPCA 2B4UA 3S3KA 1FQ1A 2CNIA 2NV5A 3V0HA 1BZCA 1C87A 3GXHA 2B07A 4GE5A 3BRHA 4JNBA 1WAXA 3ZM1A 2HNQA 3V0GA 3O3LA 2AHSA 4RI5A 4OHEA 2HVLA 2Y2FA 1C86A 3QCIA 2BGEA 5BZXA 5K25A 2QBQA 4QAPA 2HXPA 4D3QA 2I3UA 2VEWA 2A3KA 5AWXA 3F9AA 3V0FA 1JLNA 4NYHA 3S4EA 3QCHA 1JF7A 5LXQB 3CWEA 3O5XA 1C88A 2AZRA 3B7OA 3F81A 1Q6TA 3I36A 1OEOX 1MKPA 3O4UA 4DGXA 3S3FA 5BUGA 3N0AA 1NWLA 2I4GA 2HB1A 1SUGA 2ZMMA 1KAVA 4RH9A 1Q1MA 1T48A 4B04A 1T49A 2OOQA 4BJOA 4RDDA 1NO6A 3O4TA 1I9SA 1I57A 3EMUA 1LARA 2C46A 1YWFA 4H34A 2B3OA 3BLUA 1QZ0A 2HC2A 4GE2A 4R0TA 4JBCA 3F9BA 5KABA 1Q6SA 3BM8A 2F6ZA 2BV5A 2QDPA 1OHCA 2VEYA 2H04A 1PYNA 2SHPA 4GFUA 1V3AA 3V0EA 3QCCA 2VEXA 1ZCKA 2E0TA 5KA3A 3QCDA 2M3VA 2YDUA 3QCGA 5K22A 3EU0A 2PSZA 1YTWA 1YFOA 2CNFA 2F46A 2CMBA 3RGQA 2G59A 4Y14A 1G1FA 1NNYA 4JMKA 5KA0A 5EHPA 4S0GA 3F41A 5EHRA 5GTJA 5IBMA 2F6FA 3ZM2A 1KAKA 2F6YA 2CM2A 3PS5A 1C84A 2PQ5A 1ONZA 5KA9A 1PTYA 2G6ZA 1GWZA 2H02A 3EB1A 4ICZA 5BX1A 2ZN7A 1OETA 1PTUA 3V0JA 4OHHA 4GS0A 2OZ5A 1NZ7A 4RI4A 1Q6JA 2Y96A 3BLTA 3MOZA 3AWGA 1ZC0A 2OUDA 2PT0A 3D1HA 2QCJA 2NTAA 1YPTA 3RGOA 3QCLA 4NNDA 2BGDA 1ZCLA 2QEPA 3EAXA 1VHRA 3H2XA 1RPMA 3RO1A 2CMAA 1L8KA 1LYVA 3AWEA 2P6XA 2NLKA 2I6PA 2P4DA 1EENA 2I3RA 5KA8A 4GRYA 3S4OA 1LQFA 1X24A 4QBEA 2I75A 1ECVA 2MBCA 2PBNA 4TVVA 4Y2EA 2QDMA 3RZ2A 3A5KA 1G4WR 3A5JA 2H4VA 2QDCA 1YGRA 5K9VA 4QUMA 3EZZA 3QCBA 3V0DA 1AAXA 1XRIA 1C83A 3I80A 2HY3A 3U96A 3QCKA 2NT7A 2QBPA 3ZM0A 5KA4A 4GRZA 4YR8B 3QCFA 3QKQA 4HJPA 3D1OA 4MBBA 1XBOA 2C7SA 2RF6A 3QCNA 5J8RA 3M4UA 5I6VA 5KA7A 3AWFA 2DXPA 2J16A 4GFVA 1R6HA 1YZ4A 5KACA 1I9TA 2I4HA 2JJDA 5KADA 4NWGA 3I7ZA 2CM3A 2R0BA 2FH7A 1G4US 2QBRA 3D9CA 1A5YA 5M43A 2F71A 2VEUA 1G7GA 1PA9A 1U25A 4WTYA 1OESA 2I6OA 2CJZA 4R0SA 1WCHA 1WRMA 3GXGA 2Q05A 1YTSA 4D3PA 1Q6PA 3F99A 4JMJA 4WU2A 1OEVA 2A8BA 2QCTA 1U24A 2CM7A 1PTVA 1XXPA 2CNEA 1U26A 4KYRA 4J51A 4OHDA 5HDEA 2I6JA 2I5XA 4OHIA 2NZ6A 4ERCA 4GWFA 4QAHA 3D42A 2I4EA 3ZMPA 4YAAA 4PYHA 2PA5A 2NT2A 2VEVA 2FJNA 3D44A 4ZI4A 4ZRTA 1PTTA 4DGPA 1NL9A 3SMEA 2B4SA 2PI7A 5K23A 1OEMX 4GE6A 5K24A 2I1YA 2CM8A 4WOHA 4IKCA 1EEOA 2HCMA 2F70A 2FJMA 4RHGA 1OEUA 1BZHA 2H4GA 1G7FA 3QCMA 4OHLA 4QBWA 5KAAA 2F6VA 1PH0A 1YGUA 4AZ1A 1ZZWA 1P15A 2CFVA 4R30A 2BZLA 2J17A 1NWEA 3O4SA 4Z6BA 4RKKA 1QXKA 1C85A 2HNPA 3ZV2A 1PA1A 2WGPA 3QCJA 5MMZB 4D3RA 1PXHA 4KI9A 2CMCA 5BZZA 4NX8A 1D5RA 1ONYA 1RXDA 5KA1A 2F6TA
chains in the Genus database with same CATH superfamily
3MMJA 2IMGA 2B4OA 1XXVA 1M3GA 1Q6MA 3CM3A 2GWOA 2HC1A 1UAGA 3ZMQA 2J16B 4CVLA 2GJTA 5KA2A 1YN9A 1FPZA 4I8NA 5IBSA 3S3EA 4PVGA 4NWFA 4H1OA 4ZN5A 5K9WA 1T4JA 4HJQA 2VORA 1G1GA 2BIJA 2CNGA 2F6WA 2AM1A 3LJ8A 3QCZA 3SR9A 2ESBA 2WJPA 2B4PA 1OHEA 2B49A 2Q47A 1OHDA 2I6MA 2VOSA 3ZL8A 1G1HA 4WU3A 2H4KA 1FGSA 3OMHA 2H03A 4C13A 3D1QA 3NRSA 1GG4A 2I42A 3QKPA 4RH5A 2I6IA 2GP0A 1GFYA 1Q6NA 1J4XA 3S3HA 4KYQA 1FPRA 3NMEA 2QBSA 1L8GA 1XM2A 4HRFA 3OLRA 4QUNA 3QCEA 3ZM3A 3MOWA 1BZJA 3V0IA 1YTNA 2OC3A 1GQQA 2CNHA 4BPCA 2JFGA 2B4UA 3S3KA 1FQ1A 2CNIA 2NV5A 3V0HA 1BZCA 1C87A 3GXHA 2B07A 4GE5A 3BRHA 4JNBA 1WAXA 3ZM1A 3ZM5A 2HNQA 3V0GA 3O3LA 2AHSA 1E8CA 4RI5A 4OHEA 2HVLA 2Y2FA 1C86A 3QCIA 2BGEA 5BZXA 5K25A 4HV4A 2QBQA 4QAPA 2HXPA 4D3QA 2I3UA 2VTDA 2VEWA 2A3KA 5AWXA 3F9AA 3V0FA 1JLNA 4NYHA 3S4EA 3QCHA 1JF7A 5LXQB 3CWEA 3O5XA 2GCBA 1C88A 2AZRA 3B7OA 3F81A 1Q6TA 3I36A 1OEOX 1MKPA 3O4UA 4DGXA 3S3FA 2WTZA 5BUGA 3LK7A 3N0AA 1NWLA 2I4GA 2HB1A 1SUGA 2ZMMA 2XPCA 5A5EA 1KAVA 4RH9A 1Q1MA 1T48A 4B04A 1T49A 2OOQA 4BJOA 4RDDA 1NO6A 3O4TA 1I9SA 1I57A 3EMUA 1LARA 2C46A 3ZM6A 1YWFA 4H34A 2B3OA 3BLUA 1QZ0A 2HC2A 4GE2A 4R0TA 4JBCA 3F9BA 5KABA 1Q6SA 3BM8A 2F6ZA 2BV5A 2QDPA 4CVMA 1OHCA 2VEYA 2H04A 1PYNA 4BUCA 2Y67A 2SHPA 4GFUA 1V3AA 3V0EA 3QCCA 2VEXA 1ZCKA 2E0TA 5KA3A 3QCDA 1W7KA 2M3VA 2YDUA 2GC6A 3UAGA 3QCGA 5K22A 3EU0A 2PSZA 1J6UA 1YTWA 1YFOA 2CNFA 2F46A 2CMBA 2UUOA 3RGQA 2G59A 4Y14A 1G1FA 1NNYA 4JMKA 5KA0A 5EHPA 4S0GA 3F41A 5EHRA 5GTJA 5IBMA 2X5OA 2F6FA 3ZM2A 1KAKA 2F6YA 2CM2A 3PS5A 1C84A 2PQ5A 1ONZA 5KA9A 1PTYA 2G6ZA 1GWZA 2H02A 3EB1A 4ICZA 5BX1A 2ZN7A 1OETA 1PTUA 4CVKA 3V0JA 4OHHA 4GS0A 2OZ5A 1NZ7A 4RI4A 1W78A 1Q6JA 2Y96A 3BLTA 3MOZA 3AWGA 1ZC0A 2JFHA 2OUDA 4QDIA 2PT0A 3D1HA 2QCJA 2NTAA 1YPTA 2XJAA 3RGOA 3QCLA 4NNDA 2BGDA 1ZCLA 2QEPA 3EAXA 1VHRA 3H2XA 1RPMA 3RO1A 2CMAA 1L8KA 1LYVA 1EEHA 3AWEA 2P6XA 2NLKA 2I6PA 2P4DA 4BUBA 1E0DA 1EENA 2I3RA 5KA8A 4GRYA 3S4OA 1LQFA 1X24A 4QBEA 2I75A 2JFFA 1ECVA 2MBCA 2PBNA 4TVVA 4Y2EA 2QDMA 3RZ2A 3A5KA 1G4WR 3A5JA 2H4VA 2QDCA 2GCAA 1YGRA 5K9VA 4QUMA 3EZZA 3QCBA 3V0DA 1AAXA 1XRIA 1C83A 3I80A 2HY3A 3U96A 3QCKA 2NT7A 2QBPA 3ZM0A 1O5ZA 4GRZA 5KA4A 4YR8B 3QCFA 3QKQA 4HJPA 3D1OA 4MBBA 1XBOA 2C7SA 4QF5A 2RF6A 3QCNA 5J8RA 3M4UA 5A5FA 5I6VA 3MVNA 5KA7A 3AWFA 2DXPA 2J16A 4GFVA 1R6HA 1YZ4A 5KACA 3HN7A 1JBWA 1I9TA 2I4HA 2JJDA 5KADA 3N2AA 4NWGA 2AM2A 3I7ZA 2CM3A 2R0BA 2GC5A 2VTEA 2FH7A 1G4US 2QBRA 3D9CA 1A5YA 5M43A 2F71A 2VEUA 1G7GA 1PA9A 1U25A 4WTYA 1OESA 2I6OA 2CJZA 4R0SA 1WCHA 1WRMA 3GXGA 2Q05A 1YTSA 4D3PA 1Q6PA 3F99A 4JMJA 4WU2A 1OEVA 2Y68A 2A8BA 2QCTA 1U24A 2CM7A 1PTVA 1XXPA 2CNEA 1U26A 4KYRA 4J51A 3PYZA 4OHDA 5HDEA 2UAGA 2I6JA 2I5XA 4OHIA 2NZ6A 4ERCA 4GWFA 4QAHA 3D42A 2I4EA 3ZMPA 4YAAA 4PYHA 2PA5A 2NT2A 4ZIYA 2VEVA 2FJNA 3D44A 4ZI4A 4ZRTA 1PTTA 4UAGA 4DGPA 1NL9A 3SMEA 2B4SA 2PI7A 5K23A 1OEMX 1JBVA 4GE6A 5K24A 2I1YA 2CM8A 4WOHA 4IKCA 1EEOA 2HCMA 2F00A 1P3DA 1GQYA 2F70A 2UUPA 2FJMA 4RHGA 1OEUA 1BZHA 2H4GA 1G7FA 2Y66A 3QCMA 4OHLA 4QBWA 5KAAA 2F6VA 1PH0A 1P31A 1YGUA 2Y1OA 4AZ1A 1ZZWA 1P15A 2CFVA 4R30A 4C12A 2BZLA 2J17A 1NWEA 3O4SA 4Z6BA 4RKKA 1QXKA 1C85A 2HNPA 3ZV2A 1PA1A 2WGPA 3QCJA 5MMZB 4D3RA 1PXHA 4KI9A 2CMCA 5BZZA 4NX8A 1D5RA 1ONYA 1RXDA 5KA1A 2F6TA
chains in the Genus database with same CATH topology
3MMJA 2IMGA 2B4OA 1XXVA 1M3GA 1Q6MA 3CM3A 2GWOA 2HC1A 3ZMQA 2J16B 2GJTA 5KA2A 1YN9A 1FPZA 4I8NA 5IBSA 3S3EA 4PVGA 4NWFA 4H1OA 4ZN5A 5K9WA 1T4JA 4HJQA 1G1GA 2BIJA 2CNGA 2F6WA 3LJ8A 3SR9A 2ESBA 2B4PA 1OHEA 2B49A 2Q47A 1OHDA 2I6MA 1G1HA 4WU3A 2H4KA 3OMHA 2H03A 3D1QA 2I42A 3QKPA 4RH5A 2I6IA 2GP0A 1GFYA 1Q6NA 1J4XA 3S3HA 4KYQA 1FPRA 3NMEA 2QBSA 1L8GA 1XM2A 4HRFA 3OLRA 4QUNA 3QCEA 3ZM3A 3MOWA 1BZJA 3V0IA 1YTNA 2OC3A 2CNHA 4BPCA 2B4UA 3S3KA 1FQ1A 2CNIA 2NV5A 3V0HA 1BZCA 1C87A 3GXHA 2B07A 4GE5A 3BRHA 4JNBA 1WAXA 3ZM1A 2HNQA 3V0GA 3O3LA 2AHSA 4RI5A 4OHEA 2HVLA 2Y2FA 1C86A 3QCIA 2BGEA 5BZXA 5K25A 2QBQA 4QAPA 2HXPA 4D3QA 2I3UA 2VEWA 2A3KA 5AWXA 3F9AA 3V0FA 1JLNA 4NYHA 3S4EA 3QCHA 1JF7A 5LXQB 3CWEA 3O5XA 1C88A 2AZRA 3B7OA 3F81A 1Q6TA 3I36A 1OEOX 1MKPA 3O4UA 4DGXA 3S3FA 5BUGA 3N0AA 1NWLA 2I4GA 2HB1A 1SUGA 2ZMMA 1KAVA 4RH9A 1Q1MA 1T48A 4B04A 1T49A 2OOQA 4BJOA 4RDDA 1NO6A 3O4TA 1I9SA 1I57A 3EMUA 1LARA 2C46A 1YWFA 4H34A 2B3OA 3BLUA 1QZ0A 2HC2A 4GE2A 4R0TA 4JBCA 3F9BA 5KABA 1Q6SA 3BM8A 2F6ZA 2BV5A 2QDPA 1OHCA 2VEYA 2H04A 1PYNA 2SHPA 4GFUA 1V3AA 3V0EA 3QCCA 2VEXA 1ZCKA 2E0TA 5KA3A 3QCDA 2M3VA 2YDUA 3QCGA 5K22A 3EU0A 2PSZA 1YTWA 1YFOA 2CNFA 2F46A 2CMBA 3RGQA 2G59A 4Y14A 1G1FA 1NNYA 4JMKA 5KA0A 5EHPA 4S0GA 3F41A 5EHRA 5GTJA 5IBMA 2F6FA 3ZM2A 1KAKA 2F6YA 2CM2A 3PS5A 1C84A 2PQ5A 1ONZA 5KA9A 1PTYA 2G6ZA 1GWZA 2H02A 3EB1A 4ICZA 5BX1A 2ZN7A 1OETA 1PTUA 3V0JA 4OHHA 4GS0A 2OZ5A 1NZ7A 4RI4A 1Q6JA 2Y96A 3BLTA 3MOZA 3AWGA 1ZC0A 2OUDA 2PT0A 3D1HA 2QCJA 2NTAA 1YPTA 3RGOA 3QCLA 4NNDA 2BGDA 1ZCLA 2QEPA 3EAXA 1VHRA 3H2XA 1RPMA 3RO1A 2CMAA 1L8KA 1LYVA 3AWEA 2P6XA 2NLKA 2I6PA 2P4DA 1EENA 2I3RA 5KA8A 4GRYA 3S4OA 1LQFA 1X24A 4QBEA 2I75A 1ECVA 2MBCA 2PBNA 4TVVA 4Y2EA 2QDMA 3RZ2A 3A5KA 1G4WR 3A5JA 2H4VA 2QDCA 1YGRA 5K9VA 4QUMA 3EZZA 3QCBA 3V0DA 1AAXA 1XRIA 1C83A 3I80A 2HY3A 3U96A 3QCKA 2NT7A 2QBPA 3ZM0A 5KA4A 4GRZA 4YR8B 3QCFA 3QKQA 4HJPA 3D1OA 4MBBA 1XBOA 2C7SA 2RF6A 3QCNA 5J8RA 3M4UA 5I6VA 5KA7A 3AWFA 2DXPA 2J16A 4GFVA 1R6HA 1YZ4A 5KACA 1I9TA 2I4HA 2JJDA 5KADA 4NWGA 3I7ZA 2CM3A 2R0BA 2FH7A 1G4US 2QBRA 3D9CA 1A5YA 5M43A 2F71A 2VEUA 1G7GA 1PA9A 1U25A 4WTYA 1OESA 2I6OA 2CJZA 4R0SA 1WCHA 1WRMA 3GXGA 2Q05A 1YTSA 4D3PA 1Q6PA 3F99A 4JMJA 4WU2A 1OEVA 2A8BA 2QCTA 1U24A 2CM7A 1PTVA 1XXPA 2CNEA 1U26A 4KYRA 4J51A 4OHDA 5HDEA 2I6JA 2I5XA 4OHIA 2NZ6A 4ERCA 4GWFA 4QAHA 3D42A 2I4EA 3ZMPA 4YAAA 4PYHA 2PA5A 2NT2A 2VEVA 2FJNA 3D44A 4ZI4A 4ZRTA 1PTTA 4DGPA 1NL9A 3SMEA 2B4SA 2PI7A 5K23A 1OEMX 4GE6A 5K24A 2I1YA 2CM8A 4WOHA 4IKCA 1EEOA 2HCMA 2F70A 2FJMA 4RHGA 1OEUA 1BZHA 2H4GA 1G7FA 3QCMA 4OHLA 4QBWA 5KAAA 2F6VA 1PH0A 1YGUA 4AZ1A 1ZZWA 1P15A 2CFVA 4R30A 2BZLA 2J17A 1NWEA 3O4SA 4Z6BA 4RKKA 1QXKA 1C85A 2HNPA 3ZV2A 1PA1A 2WGPA 3QCJA 5MMZB 4D3RA 1PXHA 4KI9A 2CMCA 5BZZA 4NX8A 1D5RA 1ONYA 1RXDA 5KA1A 2F6TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MMJ A;  2IMG A;  2B4O A;  1XXV A;  1M3G A;  1Q6M A;  3CM3 A;  2GWO A;  2HC1 A;  3ZMQ A;  2J16 B;  2GJT A;  5KA2 A;  1YN9 A;  1FPZ A;  4I8N A;  5IBS A;  3S3E A;  4PVG A;  4NWF A;  4H1O A;  4ZN5 A;  5K9W A;  1T4J A;  4HJQ A;  1G1G A;  2BIJ A;  2CNG A;  2F6W A;  3LJ8 A;  3SR9 A;  2ESB A;  2B4P A;  1OHE A;  2B49 A;  2Q47 A;  1OHD A;  2I6M A;  1G1H A;  4WU3 A;  2H4K A;  3OMH A;  2H03 A;  3D1Q A;  2I42 A;  3QKP A;  4RH5 A;  2I6I A;  2GP0 A;  1GFY A;  1Q6N A;  1J4X A;  3S3H A;  4KYQ A;  1FPR A;  3NME A;  2QBS A;  1L8G A;  1XM2 A;  4HRF A;  3OLR A;  4QUN A;  3QCE A;  3ZM3 A;  3MOW A;  1BZJ A;  3V0I A;  1YTN A;  2OC3 A;  2CNH A;  4BPC A;  2B4U A;  3S3K A;  1FQ1 A;  2CNI A;  2NV5 A;  3V0H A;  1BZC A;  1C87 A;  3GXH A;  2B07 A;  4GE5 A;  3BRH A;  4JNB A;  1WAX A;  3ZM1 A;  2HNQ A;  3V0G A;  3O3L A;  2AHS A;  4RI5 A;  4OHE A;  2HVL A;  2Y2F A;  1C86 A;  3QCI A;  2BGE A;  5BZX A;  5K25 A;  2QBQ A;  4QAP A;  2HXP A;  4D3Q A;  2I3U A;  2VEW A;  2A3K A;  5AWX A;  3F9A A;  3V0F A;  1JLN A;  4NYH A;  3S4E A;  3QCH A;  1JF7 A;  5LXQ B;  3CWE A;  3O5X A;  1C88 A;  2AZR A;  3B7O A;  3F81 A;  1Q6T A;  3I36 A;  1OEO X;  1MKP A;  3O4U A;  4DGX A;  3S3F A;  5BUG A;  3N0A A;  1NWL A;  2I4G A;  2HB1 A;  1SUG A;  2ZMM A;  1KAV A;  4RH9 A;  1Q1M A;  1T48 A;  4B04 A;  1T49 A;  2OOQ A;  4BJO A;  4RDD A;  1NO6 A;  3O4T A;  1I9S A;  1I57 A;  3EMU A;  1LAR A;  2C46 A;  1YWF A;  4H34 A;  2B3O A;  3BLU A;  1QZ0 A;  2HC2 A;  4GE2 A;  4R0T A;  4JBC A;  3F9B A;  5KAB A;  1Q6S A;  3BM8 A;  2F6Z A;  2BV5 A;  2QDP A;  1OHC A;  2VEY A;  2H04 A;  1PYN A;  2SHP A;  4GFU A;  1V3A A;  3V0E A;  3QCC A;  2VEX A;  1ZCK A;  2E0T A;  5KA3 A;  3QCD A;  2M3V A;  2YDU A;  3QCG A;  5K22 A;  3EU0 A;  2PSZ A;  1YTW A;  1YFO A;  2CNF A;  2F46 A;  2CMB A;  3RGQ A;  2G59 A;  4Y14 A;  1G1F A;  1NNY A;  4JMK A;  5KA0 A;  5EHP A;  4S0G A;  3F41 A;  5EHR A;  5GTJ A;  5IBM A;  2F6F A;  3ZM2 A;  1KAK A;  2F6Y A;  2CM2 A;  3PS5 A;  1C84 A;  2PQ5 A;  1ONZ A;  5KA9 A;  1PTY A;  2G6Z A;  1GWZ A;  2H02 A;  3EB1 A;  4ICZ A;  5BX1 A;  2ZN7 A;  1OET A;  1PTU A;  3V0J A;  4OHH A;  4GS0 A;  2OZ5 A;  1NZ7 A;  4RI4 A;  1Q6J A;  2Y96 A;  3BLT A;  3MOZ A;  3AWG A;  1ZC0 A;  2OUD A;  2PT0 A;  3D1H A;  2QCJ A;  2NTA A;  1YPT A;  3RGO A;  3QCL A;  4NND A;  2BGD A;  1ZCL A;  2QEP A;  3EAX A;  1VHR A;  3H2X A;  1RPM A;  3RO1 A;  2CMA A;  1L8K A;  1LYV A;  3AWE A;  2P6X A;  2NLK A;  2I6P A;  2P4D A;  1EEN A;  2I3R A;  5KA8 A;  4GRY A;  3S4O A;  1LQF A;  1X24 A;  4QBE A;  2I75 A;  1ECV A;  2MBC A;  2PBN A;  4TVV A;  4Y2E A;  2QDM A;  3RZ2 A;  3A5K A;  1G4W R;  3A5J A;  2H4V A;  2QDC A;  1YGR A;  5K9V A;  4QUM A;  3EZZ A;  3QCB A;  3V0D A;  1AAX A;  1XRI A;  1C83 A;  3I80 A;  2HY3 A;  3U96 A;  3QCK A;  2NT7 A;  2QBP A;  3ZM0 A;  5KA4 A;  4GRZ A;  4YR8 B;  3QCF A;  3QKQ A;  4HJP A;  3D1O A;  4MBB A;  1XBO A;  2C7S A;  2RF6 A;  3QCN A;  5J8R A;  3M4U A;  5I6V A;  5KA7 A;  3AWF A;  2DXP A;  2J16 A;  4GFV A;  1R6H A;  1YZ4 A;  5KAC A;  1I9T A;  2I4H A;  2JJD A;  5KAD A;  4NWG A;  3I7Z A;  2CM3 A;  2R0B A;  2FH7 A;  1G4U S;  2QBR A;  3D9C A;  1A5Y A;  5M43 A;  2F71 A;  2VEU A;  1G7G A;  1PA9 A;  1U25 A;  4WTY A;  1OES A;  2I6O A;  2CJZ A;  4R0S A;  1WCH A;  1WRM A;  3GXG A;  2Q05 A;  1YTS A;  4D3P A;  1Q6P A;  3F99 A;  4JMJ A;  4WU2 A;  1OEV A;  2A8B A;  2QCT A;  1U24 A;  2CM7 A;  1PTV A;  1XXP A;  2CNE A;  1U26 A;  4KYR A;  4J51 A;  4OHD A;  5HDE A;  2I6J A;  2I5X A;  4OHI A;  2NZ6 A;  4ERC A;  4GWF A;  4QAH A;  3D42 A;  2I4E A;  3ZMP A;  4YAA A;  4PYH A;  2PA5 A;  2NT2 A;  2VEV A;  2FJN A;  3D44 A;  4ZI4 A;  4ZRT A;  1PTT A;  4DGP A;  1NL9 A;  3SME A;  2B4S A;  2PI7 A;  5K23 A;  1OEM X;  4GE6 A;  5K24 A;  2I1Y A;  2CM8 A;  4WOH A;  4IKC A;  1EEO A;  2HCM A;  2F70 A;  2FJM A;  4RHG A;  1OEU A;  1BZH A;  2H4G A;  1G7F A;  3QCM A;  4OHL A;  4QBW A;  5KAA A;  2F6V A;  1PH0 A;  1YGU A;  4AZ1 A;  1ZZW A;  1P15 A;  2CFV A;  4R30 A;  2BZL A;  2J17 A;  1NWE A;  3O4S A;  4Z6B A;  4RKK A;  1QXK A;  1C85 A;  2HNP A;  3ZV2 A;  1PA1 A;  2WGP A;  3QCJ A;  5MMZ B;  4D3R A;  1PXH A;  4KI9 A;  2CMC A;  5BZZ A;  4NX8 A;  1D5R A;  1ONY A;  1RXD A;  5KA1 A;  2F6T A; 
#chains in the Genus database with same CATH topology
 3MMJ A;  2IMG A;  2B4O A;  1XXV A;  1M3G A;  1Q6M A;  3CM3 A;  2GWO A;  2HC1 A;  1UAG A;  3ZMQ A;  2J16 B;  4CVL A;  2GJT A;  5KA2 A;  1YN9 A;  1FPZ A;  4I8N A;  5IBS A;  3S3E A;  4PVG A;  4NWF A;  4H1O A;  4ZN5 A;  5K9W A;  1T4J A;  4HJQ A;  2VOR A;  1G1G A;  2BIJ A;  2CNG A;  2F6W A;  2AM1 A;  3LJ8 A;  3QCZ A;  3SR9 A;  2ESB A;  2WJP A;  2B4P A;  1OHE A;  2B49 A;  2Q47 A;  1OHD A;  2I6M A;  2VOS A;  3ZL8 A;  1G1H A;  4WU3 A;  2H4K A;  1FGS A;  3OMH A;  2H03 A;  4C13 A;  3D1Q A;  3NRS A;  1GG4 A;  2I42 A;  3QKP A;  4RH5 A;  2I6I A;  2GP0 A;  1GFY A;  1Q6N A;  1J4X A;  3S3H A;  4KYQ A;  1FPR A;  3NME A;  2QBS A;  1L8G A;  1XM2 A;  4HRF A;  3OLR A;  4QUN A;  3QCE A;  3ZM3 A;  3MOW A;  1BZJ A;  3V0I A;  1YTN A;  2OC3 A;  1GQQ A;  2CNH A;  4BPC A;  2JFG A;  2B4U A;  3S3K A;  1FQ1 A;  2CNI A;  2NV5 A;  3V0H A;  1BZC A;  1C87 A;  3GXH A;  2B07 A;  4GE5 A;  3BRH A;  4JNB A;  1WAX A;  3ZM1 A;  3ZM5 A;  2HNQ A;  3V0G A;  3O3L A;  2AHS A;  1E8C A;  4RI5 A;  4OHE A;  2HVL A;  2Y2F A;  1C86 A;  3QCI A;  2BGE A;  5BZX A;  5K25 A;  4HV4 A;  2QBQ A;  4QAP A;  2HXP A;  4D3Q A;  2I3U A;  2VTD A;  2VEW A;  2A3K A;  5AWX A;  3F9A A;  3V0F A;  1JLN A;  4NYH A;  3S4E A;  3QCH A;  1JF7 A;  5LXQ B;  3CWE A;  3O5X A;  2GCB A;  1C88 A;  2AZR A;  3B7O A;  3F81 A;  1Q6T A;  3I36 A;  1OEO X;  1MKP A;  3O4U A;  4DGX A;  3S3F A;  2WTZ A;  5BUG A;  3LK7 A;  3N0A A;  1NWL A;  2I4G A;  2HB1 A;  1SUG A;  2ZMM A;  2XPC A;  5A5E A;  1KAV A;  4RH9 A;  1Q1M A;  1T48 A;  4B04 A;  1T49 A;  2OOQ A;  4BJO A;  4RDD A;  1NO6 A;  3O4T A;  1I9S A;  1I57 A;  3EMU A;  1LAR A;  2C46 A;  3ZM6 A;  1YWF A;  4H34 A;  2B3O A;  3BLU A;  1QZ0 A;  2HC2 A;  4GE2 A;  4R0T A;  4JBC A;  3F9B A;  5KAB A;  1Q6S A;  3BM8 A;  2F6Z A;  2BV5 A;  2QDP A;  4CVM A;  1OHC A;  2VEY A;  2H04 A;  1PYN A;  4BUC A;  2Y67 A;  2SHP A;  4GFU A;  1V3A A;  3V0E A;  3QCC A;  2VEX A;  1ZCK A;  2E0T A;  5KA3 A;  3QCD A;  1W7K A;  2M3V A;  2YDU A;  2GC6 A;  3UAG A;  3QCG A;  5K22 A;  3EU0 A;  2PSZ A;  1J6U A;  1YTW A;  1YFO A;  2CNF A;  2F46 A;  2CMB A;  2UUO A;  3RGQ A;  2G59 A;  4Y14 A;  1G1F A;  1NNY A;  4JMK A;  5KA0 A;  5EHP A;  4S0G A;  3F41 A;  5EHR A;  5GTJ A;  5IBM A;  2X5O A;  2F6F A;  3ZM2 A;  1KAK A;  2F6Y A;  2CM2 A;  3PS5 A;  1C84 A;  2PQ5 A;  1ONZ A;  5KA9 A;  1PTY A;  2G6Z A;  1GWZ A;  2H02 A;  3EB1 A;  4ICZ A;  5BX1 A;  2ZN7 A;  1OET A;  1PTU A;  4CVK A;  3V0J A;  4OHH A;  4GS0 A;  2OZ5 A;  1NZ7 A;  4RI4 A;  1W78 A;  1Q6J A;  2Y96 A;  3BLT A;  3MOZ A;  3AWG A;  1ZC0 A;  2JFH A;  2OUD A;  4QDI A;  2PT0 A;  3D1H A;  2QCJ A;  2NTA A;  1YPT A;  2XJA A;  3RGO A;  3QCL A;  4NND A;  2BGD A;  1ZCL A;  2QEP A;  3EAX A;  1VHR A;  3H2X A;  1RPM A;  3RO1 A;  2CMA A;  1L8K A;  1LYV A;  1EEH A;  3AWE A;  2P6X A;  2NLK A;  2I6P A;  2P4D A;  4BUB A;  1E0D A;  1EEN A;  2I3R A;  5KA8 A;  4GRY A;  3S4O A;  1LQF A;  1X24 A;  4QBE A;  2I75 A;  2JFF A;  1ECV A;  2MBC A;  2PBN A;  4TVV A;  4Y2E A;  2QDM A;  3RZ2 A;  3A5K A;  1G4W R;  3A5J A;  2H4V A;  2QDC A;  2GCA A;  1YGR A;  5K9V A;  4QUM A;  3EZZ A;  3QCB A;  3V0D A;  1AAX A;  1XRI A;  1C83 A;  3I80 A;  2HY3 A;  3U96 A;  3QCK A;  2NT7 A;  2QBP A;  3ZM0 A;  1O5Z A;  4GRZ A;  5KA4 A;  4YR8 B;  3QCF A;  3QKQ A;  4HJP A;  3D1O A;  4MBB A;  1XBO A;  2C7S A;  4QF5 A;  2RF6 A;  3QCN A;  5J8R A;  3M4U A;  5A5F A;  5I6V A;  3MVN A;  5KA7 A;  3AWF A;  2DXP A;  2J16 A;  4GFV A;  1R6H A;  1YZ4 A;  5KAC A;  3HN7 A;  1JBW A;  1I9T A;  2I4H A;  2JJD A;  5KAD A;  3N2A A;  4NWG A;  2AM2 A;  3I7Z A;  2CM3 A;  2R0B A;  2GC5 A;  2VTE A;  2FH7 A;  1G4U S;  2QBR A;  3D9C A;  1A5Y A;  5M43 A;  2F71 A;  2VEU A;  1G7G A;  1PA9 A;  1U25 A;  4WTY A;  1OES A;  2I6O A;  2CJZ A;  4R0S A;  1WCH A;  1WRM A;  3GXG A;  2Q05 A;  1YTS A;  4D3P A;  1Q6P A;  3F99 A;  4JMJ A;  4WU2 A;  1OEV A;  2Y68 A;  2A8B A;  2QCT A;  1U24 A;  2CM7 A;  1PTV A;  1XXP A;  2CNE A;  1U26 A;  4KYR A;  4J51 A;  3PYZ A;  4OHD A;  5HDE A;  2UAG A;  2I6J A;  2I5X A;  4OHI A;  2NZ6 A;  4ERC A;  4GWF A;  4QAH A;  3D42 A;  2I4E A;  3ZMP A;  4YAA A;  4PYH A;  2PA5 A;  2NT2 A;  4ZIY A;  2VEV A;  2FJN A;  3D44 A;  4ZI4 A;  4ZRT A;  1PTT A;  4UAG A;  4DGP A;  1NL9 A;  3SME A;  2B4S A;  2PI7 A;  5K23 A;  1OEM X;  1JBV A;  4GE6 A;  5K24 A;  2I1Y A;  2CM8 A;  4WOH A;  4IKC A;  1EEO A;  2HCM A;  2F00 A;  1P3D A;  1GQY A;  2F70 A;  2UUP A;  2FJM A;  4RHG A;  1OEU A;  1BZH A;  2H4G A;  1G7F A;  2Y66 A;  3QCM A;  4OHL A;  4QBW A;  5KAA A;  2F6V A;  1PH0 A;  1P31 A;  1YGU A;  2Y1O A;  4AZ1 A;  1ZZW A;  1P15 A;  2CFV A;  4R30 A;  4C12 A;  2BZL A;  2J17 A;  1NWE A;  3O4S A;  4Z6B A;  4RKK A;  1QXK A;  1C85 A;  2HNP A;  3ZV2 A;  1PA1 A;  2WGP A;  3QCJ A;  5MMZ B;  4D3R A;  1PXH A;  4KI9 A;  2CMC A;  5BZZ A;  4NX8 A;  1D5R A;  1ONY A;  1RXD A;  5KA1 A;  2F6T A; 
#chains in the Genus database with same CATH homology
 3MMJ A;  2IMG A;  2B4O A;  1XXV A;  1M3G A;  1Q6M A;  3CM3 A;  2GWO A;  2HC1 A;  3ZMQ A;  2J16 B;  2GJT A;  5KA2 A;  1YN9 A;  1FPZ A;  4I8N A;  5IBS A;  3S3E A;  4PVG A;  4NWF A;  4H1O A;  4ZN5 A;  5K9W A;  1T4J A;  4HJQ A;  1G1G A;  2BIJ A;  2CNG A;  2F6W A;  3LJ8 A;  3SR9 A;  2ESB A;  2B4P A;  1OHE A;  2B49 A;  2Q47 A;  1OHD A;  2I6M A;  1G1H A;  4WU3 A;  2H4K A;  3OMH A;  2H03 A;  3D1Q A;  2I42 A;  3QKP A;  4RH5 A;  2I6I A;  2GP0 A;  1GFY A;  1Q6N A;  1J4X A;  3S3H A;  4KYQ A;  1FPR A;  3NME A;  2QBS A;  1L8G A;  1XM2 A;  4HRF A;  3OLR A;  4QUN A;  3QCE A;  3ZM3 A;  3MOW A;  1BZJ A;  3V0I A;  1YTN A;  2OC3 A;  2CNH A;  4BPC A;  2B4U A;  3S3K A;  1FQ1 A;  2CNI A;  2NV5 A;  3V0H A;  1BZC A;  1C87 A;  3GXH A;  2B07 A;  4GE5 A;  3BRH A;  4JNB A;  1WAX A;  3ZM1 A;  2HNQ A;  3V0G A;  3O3L A;  2AHS A;  4RI5 A;  4OHE A;  2HVL A;  2Y2F A;  1C86 A;  3QCI A;  2BGE A;  5BZX A;  5K25 A;  2QBQ A;  4QAP A;  2HXP A;  4D3Q A;  2I3U A;  2VEW A;  2A3K A;  5AWX A;  3F9A A;  3V0F A;  1JLN A;  4NYH A;  3S4E A;  3QCH A;  1JF7 A;  5LXQ B;  3CWE A;  3O5X A;  1C88 A;  2AZR A;  3B7O A;  3F81 A;  1Q6T A;  3I36 A;  1OEO X;  1MKP A;  3O4U A;  4DGX A;  3S3F A;  5BUG A;  3N0A A;  1NWL A;  2I4G A;  2HB1 A;  1SUG A;  2ZMM A;  1KAV A;  4RH9 A;  1Q1M A;  1T48 A;  4B04 A;  1T49 A;  2OOQ A;  4BJO A;  4RDD A;  1NO6 A;  3O4T A;  1I9S A;  1I57 A;  3EMU A;  1LAR A;  2C46 A;  1YWF A;  4H34 A;  2B3O A;  3BLU A;  1QZ0 A;  2HC2 A;  4GE2 A;  4R0T A;  4JBC A;  3F9B A;  5KAB A;  1Q6S A;  3BM8 A;  2F6Z A;  2BV5 A;  2QDP A;  1OHC A;  2VEY A;  2H04 A;  1PYN A;  2SHP A;  4GFU A;  1V3A A;  3V0E A;  3QCC A;  2VEX A;  1ZCK A;  2E0T A;  5KA3 A;  3QCD A;  2M3V A;  2YDU A;  3QCG A;  5K22 A;  3EU0 A;  2PSZ A;  1YTW A;  1YFO A;  2CNF A;  2F46 A;  2CMB A;  3RGQ A;  2G59 A;  4Y14 A;  1G1F A;  1NNY A;  4JMK A;  5KA0 A;  5EHP A;  4S0G A;  3F41 A;  5EHR A;  5GTJ A;  5IBM A;  2F6F A;  3ZM2 A;  1KAK A;  2F6Y A;  2CM2 A;  3PS5 A;  1C84 A;  2PQ5 A;  1ONZ A;  5KA9 A;  1PTY A;  2G6Z A;  1GWZ A;  2H02 A;  3EB1 A;  4ICZ A;  5BX1 A;  2ZN7 A;  1OET A;  1PTU A;  3V0J A;  4OHH A;  4GS0 A;  2OZ5 A;  1NZ7 A;  4RI4 A;  1Q6J A;  2Y96 A;  3BLT A;  3MOZ A;  3AWG A;  1ZC0 A;  2OUD A;  2PT0 A;  3D1H A;  2QCJ A;  2NTA A;  1YPT A;  3RGO A;  3QCL A;  4NND A;  2BGD A;  1ZCL A;  2QEP A;  3EAX A;  1VHR A;  3H2X A;  1RPM A;  3RO1 A;  2CMA A;  1L8K A;  1LYV A;  3AWE A;  2P6X A;  2NLK A;  2I6P A;  2P4D A;  1EEN A;  2I3R A;  5KA8 A;  4GRY A;  3S4O A;  1LQF A;  1X24 A;  4QBE A;  2I75 A;  1ECV A;  2MBC A;  2PBN A;  4TVV A;  4Y2E A;  2QDM A;  3RZ2 A;  3A5K A;  1G4W R;  3A5J A;  2H4V A;  2QDC A;  1YGR A;  5K9V A;  4QUM A;  3EZZ A;  3QCB A;  3V0D A;  1AAX A;  1XRI A;  1C83 A;  3I80 A;  2HY3 A;  3U96 A;  3QCK A;  2NT7 A;  2QBP A;  3ZM0 A;  5KA4 A;  4GRZ A;  4YR8 B;  3QCF A;  3QKQ A;  4HJP A;  3D1O A;  4MBB A;  1XBO A;  2C7S A;  2RF6 A;  3QCN A;  5J8R A;  3M4U A;  5I6V A;  5KA7 A;  3AWF A;  2DXP A;  2J16 A;  4GFV A;  1R6H A;  1YZ4 A;  5KAC A;  1I9T A;  2I4H A;  2JJD A;  5KAD A;  4NWG A;  3I7Z A;  2CM3 A;  2R0B A;  2FH7 A;  1G4U S;  2QBR A;  3D9C A;  1A5Y A;  5M43 A;  2F71 A;  2VEU A;  1G7G A;  1PA9 A;  1U25 A;  4WTY A;  1OES A;  2I6O A;  2CJZ A;  4R0S A;  1WCH A;  1WRM A;  3GXG A;  2Q05 A;  1YTS A;  4D3P A;  1Q6P A;  3F99 A;  4JMJ A;  4WU2 A;  1OEV A;  2A8B A;  2QCT A;  1U24 A;  2CM7 A;  1PTV A;  1XXP A;  2CNE A;  1U26 A;  4KYR A;  4J51 A;  4OHD A;  5HDE A;  2I6J A;  2I5X A;  4OHI A;  2NZ6 A;  4ERC A;  4GWF A;  4QAH A;  3D42 A;  2I4E A;  3ZMP A;  4YAA A;  4PYH A;  2PA5 A;  2NT2 A;  2VEV A;  2FJN A;  3D44 A;  4ZI4 A;  4ZRT A;  1PTT A;  4DGP A;  1NL9 A;  3SME A;  2B4S A;  2PI7 A;  5K23 A;  1OEM X;  4GE6 A;  5K24 A;  2I1Y A;  2CM8 A;  4WOH A;  4IKC A;  1EEO A;  2HCM A;  2F70 A;  2FJM A;  4RHG A;  1OEU A;  1BZH A;  2H4G A;  1G7F A;  3QCM A;  4OHL A;  4QBW A;  5KAA A;  2F6V A;  1PH0 A;  1YGU A;  4AZ1 A;  1ZZW A;  1P15 A;  2CFV A;  4R30 A;  2BZL A;  2J17 A;  1NWE A;  3O4S A;  4Z6B A;  4RKK A;  1QXK A;  1C85 A;  2HNP A;  3ZV2 A;  1PA1 A;  2WGP A;  3QCJ A;  5MMZ B;  4D3R A;  1PXH A;  4KI9 A;  2CMC A;  5BZZ A;  4NX8 A;  1D5R A;  1ONY A;  1RXD A;  5KA1 A;  2F6T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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