1G1GA

Crystal structure of protein tyrosine phosphatase 1b complexed with a mono-phosphorylated peptide (etdy(ptr)rkggkgll) from the insulin receptor kinase
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
298
structure length
298
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHASAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.
pubmed doi rcsb
molecule tags Hydrolase, signaling protein
source organism Homo sapiens
molecule keywords PROTEIN TYROSINE PHOSPHATASE 1B
total genus 97
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-10-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1g1gA00
2HNQA 1BZHA 3QKPA 2JJDA 1C85A 2F6TA 4NX8A 3BM8A 1OEVA 1FPZA 1OHCA 2FJNA 2CJZA 3D9CA 5BUGA 1FPRA 2NV5A 2G6ZA 1C88A 2J17A 1NWEA 2ZMMA 1YGUA 2CMAA 4B04A 3QKQA 1KAKA 2AHSA 1D5RA 1OESA 2CMCA 2ESBA 2I5XA 1L8GA 5EHPA 3ZMPA 1EENA 1NO6A 3F9BA 2I42A 4GE2A 2CNEA 5K24A 2I3RA 3OLRA 2B4UA 4RHGA 4NYHA 1VHRA 2F71A 1PA1A 1XXVA 3RGQA 1LYVA 1BZJA 4WTYA 4RH5A 1C84A 2FJMA 3S3FA 2PBNA 1FQ1A 3GXHA 1QXKA 1A5YA 3O4UA 2CM8A 1PA9A 1WAXA 2HXPA 1Q6PA 2AZRA 2CNHA 4OHIA 5KA1A 3H2XA 3QCCA 2WGPA 2NT2A 2GWOA 2I3UA 2YDUA 3BLUA 3ZMQA 2F70A 5K25A 1XM2A 1NNYA 1P15A 1PTTA 2PT0A 2QDMA 2I75A 1X24A 2NLKA 2J16A 4TVVA 2GJTA 1Q6MA 3GXGA 1OHEA 2VEYA 2Q05A 2HY3A 3F41A 2F6VA 2H02A 2VEUA 2OOQA 3V0DA 4JMKA 4GRZA 1C83A 1ECVA 3QCLA 3MOZA 5K9WA 2I6PA 2QBPA 4RI4A 2B4PA 3ZV2A 2CM7A 2NT7A 1G4US 1NL9A 2PI7A 5EHRA 2FH7A 1C86A 2QBRA 1I9SA 1Q1MA 4WOHA 5BZZA 1YN9A 1YGRA 1XRIA 2I1YA 2Y96A 4H34A 3F99A 5KA4A 2B4SA 4R0TA 3V0JA 2GP0A 1G1GA 2B4OA 3F81A 5BX1A 5IBSA 2CM2A 1LQFA 2H4VA 1R6HA 3D42A 5M43A 4I8NA 1Q6JA 3BRHA 1SUGA 1LARA 5K9VA 2I6IA 1T4JA 1NZ7A 4NWFA 2G59A 1EEOA 3EU0A 2I6MA 3BLTA 1PYNA 4KYRA 2VEWA 3EAXA 3V0HA 3AWGA 4BJOA 3EMUA 3ZM2A 4Z6BA 5KA0A 4R0SA 4KI9A 5AWXA 2SHPA 2QEPA 2BGDA 3V0FA 5KA9A 4QAPA 1OEUA 1G1HA 2VEXA 2CNIA 2B49A 4DGXA 1T49A 2I4GA 1KAVA 2B07A 3F9AA 2DXPA 4WU2A 5KA3A 2Q47A 5K23A 2PA5A 1WCHA 2C7SA 2H03A 3S3HA 1PTUA 5KA7A 2QCTA 1G7FA 1T48A 1XXPA 4R30A 2RF6A 4NWGA 5KADA 4QBEA 4RI5A 1GWZA 1NWLA 3ZM0A 1OETA 2M3VA 2E0TA 4HJPA 1OHDA 3QCIA 4GS0A 4ZRTA 3O4TA 3S4OA 1YTSA 2H4GA 2I6OA 1YFOA 1Q6TA 3CWEA 1G4WR 4GFUA 3RO1A 3ZM3A 4NNDA 1PXHA 2NTAA 2PSZA 4PVGA 3O4SA 1G1FA 3QCGA 2F6FA 1I9TA 3N0AA 2I4EA 5LXQB 3QCHA 4GE5A 3CM3A 1RXDA 2CNFA 2H4KA 2OZ5A 1JLNA 1ZCKA 2H04A 4ICZA 4BPCA 1AAXA 4KYQA 3EZZA 4RKKA 1G7GA 5GTJA 2CFVA 4Y14A 2HCMA 1ZC0A 3QCJA 3QCEA 2HNPA 1L8KA 4QBWA 1ZZWA 1C87A 2Y2FA 2F6YA 2I6JA 5I6VA 5MMZB 3S4EA 2QDCA 4D3RA 4IKCA 4J51A 5KAAA 2HC1A 3V0IA 1GFYA 3NMEA 3QCFA 2ZN7A 2OC3A 3D1HA 4PYHA 1I57A 2HC2A 2MBCA 3EB1A 1WRMA 1XBOA 4AZ1A 1BZCA 4YR8B 1PTVA 5BZXA 4RDDA 2CMBA 1OEMX 4QUMA 3ZM1A 4GWFA 2BV5A 1V3AA 2CNGA 4D3PA 5J8RA 3S3KA 3AWFA 2A3KA 4ZI4A 4HJQA 3SMEA 3D44A 3LJ8A 5KACA 1U25A 2QDPA 3I36A 4OHLA 3QCDA 1Q6SA 2BIJA 2P6XA 3MMJA 3QCBA 1YTNA 4S0GA 3D1OA 5IBMA 1YPTA 3PS5A 3A5JA 2I4HA 2QBQA 3B7OA 2QBSA 1ONYA 5KA2A 2PQ5A 2J16B 4YAAA 2QCJA 1U24A 2F6WA 3QCNA 4Y2EA 3I80A 4HRFA 2IMGA 4GRYA 1ZCLA 2F46A 4ERCA 1J4XA 1JF7A 3AWEA 3O3LA 1MKPA 3S3EA 1ONZA 4GE6A 4WU3A 4OHHA 1RPMA 3QCMA 3RGOA 2NZ6A 3OMHA 2F6ZA 4GFVA 2HVLA 3D1QA 1PH0A 2CM3A 5KABA 4RH9A 4QAHA 4OHEA 5K22A 3I7ZA 3M4UA 1Q6NA 4MBBA 1PTYA 1M3GA 2BGEA 3SR9A 2C46A 2B3OA 2HB1A 1U26A 2OUDA 5HDEA 1OEOX 2P4DA 3MOWA 4JBCA 5KA8A 4QUNA 1YZ4A 3U96A 2A8BA 1YTWA 4JNBA 4OHDA 3RZ2A 1QZ0A 2VEVA 1YWFA 3A5KA 4D3QA 3O5XA 4JMJA 4ZN5A 4DGPA 3V0GA 3V0EA 4H1OA 2BZLA 3QCKA 2R0BA
chains in the Genus database with same CATH superfamily
2UUOA 2HNQA 1BZHA 2GC6A 2XPCA 3QKPA 2JJDA 1C85A 2F6TA 4NX8A 3BM8A 1OEVA 1FPZA 1OHCA 2FJNA 2CJZA 3D9CA 2F00A 5BUGA 1FPRA 1W78A 2NV5A 2G6ZA 1C88A 2J17A 1NWEA 2ZMMA 1YGUA 2CMAA 4B04A 2Y67A 3QKQA 1FGSA 1KAKA 2AHSA 1D5RA 1OESA 2CMCA 1GQYA 2ESBA 2I5XA 1L8GA 5EHPA 3ZMPA 1EENA 4BUCA 1NO6A 3F9BA 2I42A 4GE2A 2CNEA 5K24A 2I3RA 3OLRA 2B4UA 4RHGA 4NYHA 1VHRA 2F71A 1PA1A 1XXVA 3RGQA 1LYVA 2VORA 1BZJA 4WTYA 4RH5A 5A5EA 1C84A 2FJMA 3S3FA 2PBNA 1FQ1A 3GXHA 2JFFA 1UAGA 1QXKA 1A5YA 2CM8A 3O4UA 1PA9A 1WAXA 2HXPA 1Q6PA 2AZRA 2CNHA 4OHIA 5KA1A 3H2XA 3QCCA 2WGPA 2NT2A 2GWOA 2I3UA 2YDUA 3BLUA 3ZMQA 2F70A 5K25A 1XM2A 1NNYA 1O5ZA 1P15A 1PTTA 2PT0A 2QDMA 2I75A 1X24A 2NLKA 2J16A 4TVVA 2GJTA 1Q6MA 3GXGA 1OHEA 2VEYA 2Q05A 2HY3A 3F41A 2F6VA 2H02A 2VEUA 2OOQA 3V0DA 4JMKA 4ZIYA 3UAGA 4GRZA 1C83A 1ECVA 3QCLA 3MOZA 5K9WA 2JFGA 2I6PA 2QBPA 4RI4A 2B4PA 3ZV2A 2CM7A 2NT7A 1G4US 1NL9A 2PI7A 5EHRA 2FH7A 1C86A 2QBRA 1I9SA 1Q1MA 4WOHA 5BZZA 1YN9A 1YGRA 1XRIA 2I1YA 2Y96A 4H34A 4BUBA 3F99A 5KA4A 2B4SA 3PYZA 2UAGA 4R0TA 3V0JA 2XJAA 1P3DA 2GP0A 1G1GA 2B4OA 3F81A 5BX1A 5IBSA 2CM2A 1LQFA 3LK7A 2H4VA 1R6HA 3D42A 5M43A 4I8NA 1Q6JA 3BRHA 1SUGA 1LARA 5K9VA 2I6IA 1P31A 1T4JA 1NZ7A 4NWFA 2G59A 1EEOA 2I6MA 1E0DA 3BLTA 1PYNA 3EU0A 4KYRA 2VEWA 2WJPA 2VTEA 3EAXA 3V0HA 3AWGA 4BJOA 3EMUA 3ZM2A 4Z6BA 5KA0A 4R0SA 4KI9A 5AWXA 2SHPA 2QEPA 2BGDA 3V0FA 5KA9A 4QAPA 1OEUA 1G1HA 2X5OA 2VEXA 2CNIA 2B49A 4QF5A 4DGXA 2Y1OA 1T49A 2I4GA 1KAVA 2B07A 3F9AA 2DXPA 1GG4A 4WU2A 5KA3A 2Q47A 5K23A 2PA5A 1JBVA 1WCHA 2C7SA 3N2AA 2H03A 3S3HA 1PTUA 5KA7A 2QCTA 1G7FA 1T48A 1XXPA 4R30A 2GC5A 2RF6A 4NWGA 5KADA 4QBEA 4QDIA 4RI5A 1GWZA 1NWLA 3ZM0A 1OETA 2M3VA 3ZL8A 2E0TA 4HJPA 1OHDA 3QCIA 4GS0A 4ZRTA 3O4TA 1W7KA 3S4OA 1YTSA 2H4GA 2I6OA 2WTZA 1YFOA 1Q6TA 3CWEA 1G4WR 4GFUA 4CVMA 3RO1A 3ZM3A 4NNDA 1PXHA 2NTAA 2GCAA 2PSZA 3HN7A 4PVGA 3O4SA 1G1FA 3QCGA 2F6FA 1I9TA 3N0AA 3MVNA 2I4EA 5LXQB 3QCHA 4GE5A 3CM3A 1RXDA 2CNFA 2H4KA 2OZ5A 2AM1A 1JLNA 1ZCKA 2H04A 4ICZA 4HV4A 4BPCA 1AAXA 4KYQA 3QCZA 3EZZA 4RKKA 1G7GA 2VOSA 5GTJA 2CFVA 2AM2A 4Y14A 2HCMA 1ZC0A 3QCJA 3QCEA 2HNPA 1L8KA 4QBWA 2Y66A 1ZZWA 1C87A 2Y2FA 2F6YA 2I6JA 5I6VA 5MMZB 3S4EA 3NRSA 2QDCA 4C12A 5A5FA 4D3RA 4IKCA 4J51A 5KAAA 2HC1A 2UUPA 3V0IA 1GFYA 3NMEA 3QCFA 3ZM6A 2ZN7A 2OC3A 3D1HA 4PYHA 1I57A 2JFHA 2HC2A 2MBCA 2GCBA 3EB1A 1WRMA 1XBOA 4AZ1A 1BZCA 4YR8B 1PTVA 5BZXA 4RDDA 2CMBA 1OEMX 4QUMA 3ZM1A 4GWFA 2BV5A 1V3AA 2CNGA 4D3PA 5J8RA 3S3KA 3AWFA 2A3KA 4ZI4A 4HJQA 3SMEA 3D44A 3LJ8A 5KACA 1U25A 2QDPA 3I36A 4OHLA 3QCDA 1Q6SA 2BIJA 2P6XA 3MMJA 3QCBA 2VTDA 1YTNA 4S0GA 3D1OA 5IBMA 1YPTA 3PS5A 3A5JA 2I4HA 1JBWA 2QBQA 3B7OA 1GQQA 2QBSA 1ONYA 5KA2A 2PQ5A 1J6UA 2J16B 4YAAA 2QCJA 1U24A 2F6WA 3QCNA 4Y2EA 3I80A 4HRFA 2IMGA 4GRYA 1ZCLA 2F46A 4ERCA 1J4XA 1JF7A 3AWEA 3O3LA 1MKPA 3S3EA 1ONZA 4GE6A 4WU3A 4OHHA 1RPMA 3QCMA 3RGOA 2NZ6A 3OMHA 2F6ZA 4GFVA 2HVLA 3D1QA 1PH0A 2CM3A 5KABA 4RH9A 4QAHA 4OHEA 5K22A 3I7ZA 3M4UA 1Q6NA 4MBBA 1PTYA 1M3GA 2BGEA 3SR9A 2Y68A 2C46A 2B3OA 2HB1A 1U26A 4C13A 2OUDA 5HDEA 1OEOX 4CVLA 4UAGA 2P4DA 3MOWA 1EEHA 4JBCA 5KA8A 4CVKA 4QUNA 1YZ4A 3U96A 2A8BA 1YTWA 4JNBA 4OHDA 3RZ2A 1QZ0A 2VEVA 1YWFA 1E8CA 3A5KA 4D3QA 3O5XA 4JMJA 4ZN5A 4DGPA 3V0GA 3V0EA 4H1OA 2BZLA 3QCKA 2R0BA 3ZM5A
chains in the Genus database with same CATH topology
2HNQA 1BZHA 3QKPA 2JJDA 1C85A 2F6TA 4NX8A 3BM8A 1OEVA 1FPZA 1OHCA 2FJNA 2CJZA 3D9CA 5BUGA 1FPRA 2NV5A 2G6ZA 1C88A 2J17A 1NWEA 2ZMMA 1YGUA 2CMAA 4B04A 3QKQA 1KAKA 2AHSA 1D5RA 1OESA 2CMCA 2ESBA 2I5XA 1L8GA 5EHPA 3ZMPA 1EENA 1NO6A 3F9BA 2I42A 4GE2A 2CNEA 5K24A 2I3RA 3OLRA 2B4UA 4RHGA 4NYHA 1VHRA 2F71A 1PA1A 1XXVA 3RGQA 1LYVA 1BZJA 4WTYA 4RH5A 1C84A 2FJMA 3S3FA 2PBNA 1FQ1A 3GXHA 1QXKA 1A5YA 3O4UA 2CM8A 1PA9A 1WAXA 2HXPA 1Q6PA 2AZRA 2CNHA 4OHIA 5KA1A 3H2XA 3QCCA 2WGPA 2NT2A 2GWOA 2I3UA 2YDUA 3BLUA 3ZMQA 2F70A 5K25A 1XM2A 1NNYA 1P15A 1PTTA 2PT0A 2QDMA 2I75A 1X24A 2NLKA 2J16A 4TVVA 2GJTA 1Q6MA 3GXGA 1OHEA 2VEYA 2Q05A 2HY3A 3F41A 2F6VA 2H02A 2VEUA 2OOQA 3V0DA 4JMKA 4GRZA 1C83A 1ECVA 3QCLA 3MOZA 5K9WA 2I6PA 2QBPA 4RI4A 2B4PA 3ZV2A 2CM7A 2NT7A 1G4US 1NL9A 2PI7A 5EHRA 2FH7A 1C86A 2QBRA 1I9SA 1Q1MA 4WOHA 5BZZA 1YN9A 1YGRA 1XRIA 2I1YA 2Y96A 4H34A 3F99A 5KA4A 2B4SA 4R0TA 3V0JA 2GP0A 1G1GA 2B4OA 3F81A 5BX1A 5IBSA 2CM2A 1LQFA 2H4VA 1R6HA 3D42A 5M43A 4I8NA 1Q6JA 3BRHA 1SUGA 1LARA 5K9VA 2I6IA 1T4JA 1NZ7A 4NWFA 2G59A 1EEOA 3EU0A 2I6MA 3BLTA 1PYNA 4KYRA 2VEWA 3EAXA 3V0HA 3AWGA 4BJOA 3EMUA 3ZM2A 4Z6BA 5KA0A 4R0SA 4KI9A 5AWXA 2SHPA 2QEPA 2BGDA 3V0FA 5KA9A 4QAPA 1OEUA 1G1HA 2VEXA 2CNIA 2B49A 4DGXA 1T49A 2I4GA 1KAVA 2B07A 3F9AA 2DXPA 4WU2A 5KA3A 2Q47A 5K23A 2PA5A 1WCHA 2C7SA 2H03A 3S3HA 1PTUA 5KA7A 2QCTA 1G7FA 1T48A 1XXPA 4R30A 2RF6A 4NWGA 5KADA 4QBEA 4RI5A 1GWZA 1NWLA 3ZM0A 1OETA 2M3VA 2E0TA 4HJPA 1OHDA 3QCIA 4GS0A 4ZRTA 3O4TA 3S4OA 1YTSA 2H4GA 2I6OA 1YFOA 1Q6TA 3CWEA 1G4WR 4GFUA 3RO1A 3ZM3A 4NNDA 1PXHA 2NTAA 2PSZA 4PVGA 3O4SA 1G1FA 3QCGA 2F6FA 1I9TA 3N0AA 2I4EA 5LXQB 3QCHA 4GE5A 3CM3A 1RXDA 2CNFA 2H4KA 2OZ5A 1JLNA 1ZCKA 2H04A 4ICZA 4BPCA 1AAXA 4KYQA 3EZZA 4RKKA 1G7GA 5GTJA 2CFVA 4Y14A 2HCMA 1ZC0A 3QCJA 3QCEA 2HNPA 1L8KA 4QBWA 1ZZWA 1C87A 2Y2FA 2F6YA 2I6JA 5I6VA 5MMZB 3S4EA 2QDCA 4D3RA 4IKCA 4J51A 5KAAA 2HC1A 3V0IA 1GFYA 3NMEA 3QCFA 2ZN7A 2OC3A 3D1HA 4PYHA 1I57A 2HC2A 2MBCA 3EB1A 1WRMA 1XBOA 4AZ1A 1BZCA 4YR8B 1PTVA 5BZXA 4RDDA 2CMBA 1OEMX 4QUMA 3ZM1A 4GWFA 2BV5A 1V3AA 2CNGA 4D3PA 5J8RA 3S3KA 3AWFA 2A3KA 4ZI4A 4HJQA 3SMEA 3D44A 3LJ8A 5KACA 1U25A 2QDPA 3I36A 4OHLA 3QCDA 1Q6SA 2BIJA 2P6XA 3MMJA 3QCBA 1YTNA 4S0GA 3D1OA 5IBMA 1YPTA 3PS5A 3A5JA 2I4HA 2QBQA 3B7OA 2QBSA 1ONYA 5KA2A 2PQ5A 2J16B 4YAAA 2QCJA 1U24A 2F6WA 3QCNA 4Y2EA 3I80A 4HRFA 2IMGA 4GRYA 1ZCLA 2F46A 4ERCA 1J4XA 1JF7A 3AWEA 3O3LA 1MKPA 3S3EA 1ONZA 4GE6A 4WU3A 4OHHA 1RPMA 3QCMA 3RGOA 2NZ6A 3OMHA 2F6ZA 4GFVA 2HVLA 3D1QA 1PH0A 2CM3A 5KABA 4RH9A 4QAHA 4OHEA 5K22A 3I7ZA 3M4UA 1Q6NA 4MBBA 1PTYA 1M3GA 2BGEA 3SR9A 2C46A 2B3OA 2HB1A 1U26A 2OUDA 5HDEA 1OEOX 2P4DA 3MOWA 4JBCA 5KA8A 4QUNA 1YZ4A 3U96A 2A8BA 1YTWA 4JNBA 4OHDA 3RZ2A 1QZ0A 2VEVA 1YWFA 3A5KA 4D3QA 3O5XA 4JMJA 4ZN5A 4DGPA 3V0GA 3V0EA 4H1OA 2BZLA 3QCKA 2R0BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HNQ A;  1BZH A;  3QKP A;  2JJD A;  1C85 A;  2F6T A;  4NX8 A;  3BM8 A;  1OEV A;  1FPZ A;  1OHC A;  2FJN A;  2CJZ A;  3D9C A;  5BUG A;  1FPR A;  2NV5 A;  2G6Z A;  1C88 A;  2J17 A;  1NWE A;  2ZMM A;  1YGU A;  2CMA A;  4B04 A;  3QKQ A;  1KAK A;  2AHS A;  1D5R A;  1OES A;  2CMC A;  2ESB A;  2I5X A;  1L8G A;  5EHP A;  3ZMP A;  1EEN A;  1NO6 A;  3F9B A;  2I42 A;  4GE2 A;  2CNE A;  5K24 A;  2I3R A;  3OLR A;  2B4U A;  4RHG A;  4NYH A;  1VHR A;  2F71 A;  1PA1 A;  1XXV A;  3RGQ A;  1LYV A;  1BZJ A;  4WTY A;  4RH5 A;  1C84 A;  2FJM A;  3S3F A;  2PBN A;  1FQ1 A;  3GXH A;  1QXK A;  1A5Y A;  3O4U A;  2CM8 A;  1PA9 A;  1WAX A;  2HXP A;  1Q6P A;  2AZR A;  2CNH A;  4OHI A;  5KA1 A;  3H2X A;  3QCC A;  2WGP A;  2NT2 A;  2GWO A;  2I3U A;  2YDU A;  3BLU A;  3ZMQ A;  2F70 A;  5K25 A;  1XM2 A;  1NNY A;  1P15 A;  1PTT A;  2PT0 A;  2QDM A;  2I75 A;  1X24 A;  2NLK A;  2J16 A;  4TVV A;  2GJT A;  1Q6M A;  3GXG A;  1OHE A;  2VEY A;  2Q05 A;  2HY3 A;  3F41 A;  2F6V A;  2H02 A;  2VEU A;  2OOQ A;  3V0D A;  4JMK A;  4GRZ A;  1C83 A;  1ECV A;  3QCL A;  3MOZ A;  5K9W A;  2I6P A;  2QBP A;  4RI4 A;  2B4P A;  3ZV2 A;  2CM7 A;  2NT7 A;  1G4U S;  1NL9 A;  2PI7 A;  5EHR A;  2FH7 A;  1C86 A;  2QBR A;  1I9S A;  1Q1M A;  4WOH A;  5BZZ A;  1YN9 A;  1YGR A;  1XRI A;  2I1Y A;  2Y96 A;  4H34 A;  3F99 A;  5KA4 A;  2B4S A;  4R0T A;  3V0J A;  2GP0 A;  1G1G A;  2B4O A;  3F81 A;  5BX1 A;  5IBS A;  2CM2 A;  1LQF A;  2H4V A;  1R6H A;  3D42 A;  5M43 A;  4I8N A;  1Q6J A;  3BRH A;  1SUG A;  1LAR A;  5K9V A;  2I6I A;  1T4J A;  1NZ7 A;  4NWF A;  2G59 A;  1EEO A;  3EU0 A;  2I6M A;  3BLT A;  1PYN A;  4KYR A;  2VEW A;  3EAX A;  3V0H A;  3AWG A;  4BJO A;  3EMU A;  3ZM2 A;  4Z6B A;  5KA0 A;  4R0S A;  4KI9 A;  5AWX A;  2SHP A;  2QEP A;  2BGD A;  3V0F A;  5KA9 A;  4QAP A;  1OEU A;  1G1H A;  2VEX A;  2CNI A;  2B49 A;  4DGX A;  1T49 A;  2I4G A;  1KAV A;  2B07 A;  3F9A A;  2DXP A;  4WU2 A;  5KA3 A;  2Q47 A;  5K23 A;  2PA5 A;  1WCH A;  2C7S A;  2H03 A;  3S3H A;  1PTU A;  5KA7 A;  2QCT A;  1G7F A;  1T48 A;  1XXP A;  4R30 A;  2RF6 A;  4NWG A;  5KAD A;  4QBE A;  4RI5 A;  1GWZ A;  1NWL A;  3ZM0 A;  1OET A;  2M3V A;  2E0T A;  4HJP A;  1OHD A;  3QCI A;  4GS0 A;  4ZRT A;  3O4T A;  3S4O A;  1YTS A;  2H4G A;  2I6O A;  1YFO A;  1Q6T A;  3CWE A;  1G4W R;  4GFU A;  3RO1 A;  3ZM3 A;  4NND A;  1PXH A;  2NTA A;  2PSZ A;  4PVG A;  3O4S A;  1G1F A;  3QCG A;  2F6F A;  1I9T A;  3N0A A;  2I4E A;  5LXQ B;  3QCH A;  4GE5 A;  3CM3 A;  1RXD A;  2CNF A;  2H4K A;  2OZ5 A;  1JLN A;  1ZCK A;  2H04 A;  4ICZ A;  4BPC A;  1AAX A;  4KYQ A;  3EZZ A;  4RKK A;  1G7G A;  5GTJ A;  2CFV A;  4Y14 A;  2HCM A;  1ZC0 A;  3QCJ A;  3QCE A;  2HNP A;  1L8K A;  4QBW A;  1ZZW A;  1C87 A;  2Y2F A;  2F6Y A;  2I6J A;  5I6V A;  5MMZ B;  3S4E A;  2QDC A;  4D3R A;  4IKC A;  4J51 A;  5KAA A;  2HC1 A;  3V0I A;  1GFY A;  3NME A;  3QCF A;  2ZN7 A;  2OC3 A;  3D1H A;  4PYH A;  1I57 A;  2HC2 A;  2MBC A;  3EB1 A;  1WRM A;  1XBO A;  4AZ1 A;  1BZC A;  4YR8 B;  1PTV A;  5BZX A;  4RDD A;  2CMB A;  1OEM X;  4QUM A;  3ZM1 A;  4GWF A;  2BV5 A;  1V3A A;  2CNG A;  4D3P A;  5J8R A;  3S3K A;  3AWF A;  2A3K A;  4ZI4 A;  4HJQ A;  3SME A;  3D44 A;  3LJ8 A;  5KAC A;  1U25 A;  2QDP A;  3I36 A;  4OHL A;  3QCD A;  1Q6S A;  2BIJ A;  2P6X A;  3MMJ A;  3QCB A;  1YTN A;  4S0G A;  3D1O A;  5IBM A;  1YPT A;  3PS5 A;  3A5J A;  2I4H A;  2QBQ A;  3B7O A;  2QBS A;  1ONY A;  5KA2 A;  2PQ5 A;  2J16 B;  4YAA A;  2QCJ A;  1U24 A;  2F6W A;  3QCN A;  4Y2E A;  3I80 A;  4HRF A;  2IMG A;  4GRY A;  1ZCL A;  2F46 A;  4ERC A;  1J4X A;  1JF7 A;  3AWE A;  3O3L A;  1MKP A;  3S3E A;  1ONZ A;  4GE6 A;  4WU3 A;  4OHH A;  1RPM A;  3QCM A;  3RGO A;  2NZ6 A;  3OMH A;  2F6Z A;  4GFV A;  2HVL A;  3D1Q A;  1PH0 A;  2CM3 A;  5KAB A;  4RH9 A;  4QAH A;  4OHE A;  5K22 A;  3I7Z A;  3M4U A;  1Q6N A;  4MBB A;  1PTY A;  1M3G A;  2BGE A;  3SR9 A;  2C46 A;  2B3O A;  2HB1 A;  1U26 A;  2OUD A;  5HDE A;  1OEO X;  2P4D A;  3MOW A;  4JBC A;  5KA8 A;  4QUN A;  1YZ4 A;  3U96 A;  2A8B A;  1YTW A;  4JNB A;  4OHD A;  3RZ2 A;  1QZ0 A;  2VEV A;  1YWF A;  3A5K A;  4D3Q A;  3O5X A;  4JMJ A;  4ZN5 A;  4DGP A;  3V0G A;  3V0E A;  4H1O A;  2BZL A;  3QCK A;  2R0B A; 
#chains in the Genus database with same CATH topology
 2UUO A;  2HNQ A;  1BZH A;  2GC6 A;  2XPC A;  3QKP A;  2JJD A;  1C85 A;  2F6T A;  4NX8 A;  3BM8 A;  1OEV A;  1FPZ A;  1OHC A;  2FJN A;  2CJZ A;  3D9C A;  2F00 A;  5BUG A;  1FPR A;  1W78 A;  2NV5 A;  2G6Z A;  1C88 A;  2J17 A;  1NWE A;  2ZMM A;  1YGU A;  2CMA A;  4B04 A;  2Y67 A;  3QKQ A;  1FGS A;  1KAK A;  2AHS A;  1D5R A;  1OES A;  2CMC A;  1GQY A;  2ESB A;  2I5X A;  1L8G A;  5EHP A;  3ZMP A;  1EEN A;  4BUC A;  1NO6 A;  3F9B A;  2I42 A;  4GE2 A;  2CNE A;  5K24 A;  2I3R A;  3OLR A;  2B4U A;  4RHG A;  4NYH A;  1VHR A;  2F71 A;  1PA1 A;  1XXV A;  3RGQ A;  1LYV A;  2VOR A;  1BZJ A;  4WTY A;  4RH5 A;  5A5E A;  1C84 A;  2FJM A;  3S3F A;  2PBN A;  1FQ1 A;  3GXH A;  2JFF A;  1UAG A;  1QXK A;  1A5Y A;  2CM8 A;  3O4U A;  1PA9 A;  1WAX A;  2HXP A;  1Q6P A;  2AZR A;  2CNH A;  4OHI A;  5KA1 A;  3H2X A;  3QCC A;  2WGP A;  2NT2 A;  2GWO A;  2I3U A;  2YDU A;  3BLU A;  3ZMQ A;  2F70 A;  5K25 A;  1XM2 A;  1NNY A;  1O5Z A;  1P15 A;  1PTT A;  2PT0 A;  2QDM A;  2I75 A;  1X24 A;  2NLK A;  2J16 A;  4TVV A;  2GJT A;  1Q6M A;  3GXG A;  1OHE A;  2VEY A;  2Q05 A;  2HY3 A;  3F41 A;  2F6V A;  2H02 A;  2VEU A;  2OOQ A;  3V0D A;  4JMK A;  4ZIY A;  3UAG A;  4GRZ A;  1C83 A;  1ECV A;  3QCL A;  3MOZ A;  5K9W A;  2JFG A;  2I6P A;  2QBP A;  4RI4 A;  2B4P A;  3ZV2 A;  2CM7 A;  2NT7 A;  1G4U S;  1NL9 A;  2PI7 A;  5EHR A;  2FH7 A;  1C86 A;  2QBR A;  1I9S A;  1Q1M A;  4WOH A;  5BZZ A;  1YN9 A;  1YGR A;  1XRI A;  2I1Y A;  2Y96 A;  4H34 A;  4BUB A;  3F99 A;  5KA4 A;  2B4S A;  3PYZ A;  2UAG A;  4R0T A;  3V0J A;  2XJA A;  1P3D A;  2GP0 A;  1G1G A;  2B4O A;  3F81 A;  5BX1 A;  5IBS A;  2CM2 A;  1LQF A;  3LK7 A;  2H4V A;  1R6H A;  3D42 A;  5M43 A;  4I8N A;  1Q6J A;  3BRH A;  1SUG A;  1LAR A;  5K9V A;  2I6I A;  1P31 A;  1T4J A;  1NZ7 A;  4NWF A;  2G59 A;  1EEO A;  2I6M A;  1E0D A;  3BLT A;  1PYN A;  3EU0 A;  4KYR A;  2VEW A;  2WJP A;  2VTE A;  3EAX A;  3V0H A;  3AWG A;  4BJO A;  3EMU A;  3ZM2 A;  4Z6B A;  5KA0 A;  4R0S A;  4KI9 A;  5AWX A;  2SHP A;  2QEP A;  2BGD A;  3V0F A;  5KA9 A;  4QAP A;  1OEU A;  1G1H A;  2X5O A;  2VEX A;  2CNI A;  2B49 A;  4QF5 A;  4DGX A;  2Y1O A;  1T49 A;  2I4G A;  1KAV A;  2B07 A;  3F9A A;  2DXP A;  1GG4 A;  4WU2 A;  5KA3 A;  2Q47 A;  5K23 A;  2PA5 A;  1JBV A;  1WCH A;  2C7S A;  3N2A A;  2H03 A;  3S3H A;  1PTU A;  5KA7 A;  2QCT A;  1G7F A;  1T48 A;  1XXP A;  4R30 A;  2GC5 A;  2RF6 A;  4NWG A;  5KAD A;  4QBE A;  4QDI A;  4RI5 A;  1GWZ A;  1NWL A;  3ZM0 A;  1OET A;  2M3V A;  3ZL8 A;  2E0T A;  4HJP A;  1OHD A;  3QCI A;  4GS0 A;  4ZRT A;  3O4T A;  1W7K A;  3S4O A;  1YTS A;  2H4G A;  2I6O A;  2WTZ A;  1YFO A;  1Q6T A;  3CWE A;  1G4W R;  4GFU A;  4CVM A;  3RO1 A;  3ZM3 A;  4NND A;  1PXH A;  2NTA A;  2GCA A;  2PSZ A;  3HN7 A;  4PVG A;  3O4S A;  1G1F A;  3QCG A;  2F6F A;  1I9T A;  3N0A A;  3MVN A;  2I4E A;  5LXQ B;  3QCH A;  4GE5 A;  3CM3 A;  1RXD A;  2CNF A;  2H4K A;  2OZ5 A;  2AM1 A;  1JLN A;  1ZCK A;  2H04 A;  4ICZ A;  4HV4 A;  4BPC A;  1AAX A;  4KYQ A;  3QCZ A;  3EZZ A;  4RKK A;  1G7G A;  2VOS A;  5GTJ A;  2CFV A;  2AM2 A;  4Y14 A;  2HCM A;  1ZC0 A;  3QCJ A;  3QCE A;  2HNP A;  1L8K A;  4QBW A;  2Y66 A;  1ZZW A;  1C87 A;  2Y2F A;  2F6Y A;  2I6J A;  5I6V A;  5MMZ B;  3S4E A;  3NRS A;  2QDC A;  4C12 A;  5A5F A;  4D3R A;  4IKC A;  4J51 A;  5KAA A;  2HC1 A;  2UUP A;  3V0I A;  1GFY A;  3NME A;  3QCF A;  3ZM6 A;  2ZN7 A;  2OC3 A;  3D1H A;  4PYH A;  1I57 A;  2JFH A;  2HC2 A;  2MBC A;  2GCB A;  3EB1 A;  1WRM A;  1XBO A;  4AZ1 A;  1BZC A;  4YR8 B;  1PTV A;  5BZX A;  4RDD A;  2CMB A;  1OEM X;  4QUM A;  3ZM1 A;  4GWF A;  2BV5 A;  1V3A A;  2CNG A;  4D3P A;  5J8R A;  3S3K A;  3AWF A;  2A3K A;  4ZI4 A;  4HJQ A;  3SME A;  3D44 A;  3LJ8 A;  5KAC A;  1U25 A;  2QDP A;  3I36 A;  4OHL A;  3QCD A;  1Q6S A;  2BIJ A;  2P6X A;  3MMJ A;  3QCB A;  2VTD A;  1YTN A;  4S0G A;  3D1O A;  5IBM A;  1YPT A;  3PS5 A;  3A5J A;  2I4H A;  1JBW A;  2QBQ A;  3B7O A;  1GQQ A;  2QBS A;  1ONY A;  5KA2 A;  2PQ5 A;  1J6U A;  2J16 B;  4YAA A;  2QCJ A;  1U24 A;  2F6W A;  3QCN A;  4Y2E A;  3I80 A;  4HRF A;  2IMG A;  4GRY A;  1ZCL A;  2F46 A;  4ERC A;  1J4X A;  1JF7 A;  3AWE A;  3O3L A;  1MKP A;  3S3E A;  1ONZ A;  4GE6 A;  4WU3 A;  4OHH A;  1RPM A;  3QCM A;  3RGO A;  2NZ6 A;  3OMH A;  2F6Z A;  4GFV A;  2HVL A;  3D1Q A;  1PH0 A;  2CM3 A;  5KAB A;  4RH9 A;  4QAH A;  4OHE A;  5K22 A;  3I7Z A;  3M4U A;  1Q6N A;  4MBB A;  1PTY A;  1M3G A;  2BGE A;  3SR9 A;  2Y68 A;  2C46 A;  2B3O A;  2HB1 A;  1U26 A;  4C13 A;  2OUD A;  5HDE A;  1OEO X;  4CVL A;  4UAG A;  2P4D A;  3MOW A;  1EEH A;  4JBC A;  5KA8 A;  4CVK A;  4QUN A;  1YZ4 A;  3U96 A;  2A8B A;  1YTW A;  4JNB A;  4OHD A;  3RZ2 A;  1QZ0 A;  2VEV A;  1YWF A;  1E8C A;  3A5K A;  4D3Q A;  3O5X A;  4JMJ A;  4ZN5 A;  4DGP A;  3V0G A;  3V0E A;  4H1O A;  2BZL A;  3QCK A;  2R0B A;  3ZM5 A; 
#chains in the Genus database with same CATH homology
 2HNQ A;  1BZH A;  3QKP A;  2JJD A;  1C85 A;  2F6T A;  4NX8 A;  3BM8 A;  1OEV A;  1FPZ A;  1OHC A;  2FJN A;  2CJZ A;  3D9C A;  5BUG A;  1FPR A;  2NV5 A;  2G6Z A;  1C88 A;  2J17 A;  1NWE A;  2ZMM A;  1YGU A;  2CMA A;  4B04 A;  3QKQ A;  1KAK A;  2AHS A;  1D5R A;  1OES A;  2CMC A;  2ESB A;  2I5X A;  1L8G A;  5EHP A;  3ZMP A;  1EEN A;  1NO6 A;  3F9B A;  2I42 A;  4GE2 A;  2CNE A;  5K24 A;  2I3R A;  3OLR A;  2B4U A;  4RHG A;  4NYH A;  1VHR A;  2F71 A;  1PA1 A;  1XXV A;  3RGQ A;  1LYV A;  1BZJ A;  4WTY A;  4RH5 A;  1C84 A;  2FJM A;  3S3F A;  2PBN A;  1FQ1 A;  3GXH A;  1QXK A;  1A5Y A;  3O4U A;  2CM8 A;  1PA9 A;  1WAX A;  2HXP A;  1Q6P A;  2AZR A;  2CNH A;  4OHI A;  5KA1 A;  3H2X A;  3QCC A;  2WGP A;  2NT2 A;  2GWO A;  2I3U A;  2YDU A;  3BLU A;  3ZMQ A;  2F70 A;  5K25 A;  1XM2 A;  1NNY A;  1P15 A;  1PTT A;  2PT0 A;  2QDM A;  2I75 A;  1X24 A;  2NLK A;  2J16 A;  4TVV A;  2GJT A;  1Q6M A;  3GXG A;  1OHE A;  2VEY A;  2Q05 A;  2HY3 A;  3F41 A;  2F6V A;  2H02 A;  2VEU A;  2OOQ A;  3V0D A;  4JMK A;  4GRZ A;  1C83 A;  1ECV A;  3QCL A;  3MOZ A;  5K9W A;  2I6P A;  2QBP A;  4RI4 A;  2B4P A;  3ZV2 A;  2CM7 A;  2NT7 A;  1G4U S;  1NL9 A;  2PI7 A;  5EHR A;  2FH7 A;  1C86 A;  2QBR A;  1I9S A;  1Q1M A;  4WOH A;  5BZZ A;  1YN9 A;  1YGR A;  1XRI A;  2I1Y A;  2Y96 A;  4H34 A;  3F99 A;  5KA4 A;  2B4S A;  4R0T A;  3V0J A;  2GP0 A;  1G1G A;  2B4O A;  3F81 A;  5BX1 A;  5IBS A;  2CM2 A;  1LQF A;  2H4V A;  1R6H A;  3D42 A;  5M43 A;  4I8N A;  1Q6J A;  3BRH A;  1SUG A;  1LAR A;  5K9V A;  2I6I A;  1T4J A;  1NZ7 A;  4NWF A;  2G59 A;  1EEO A;  3EU0 A;  2I6M A;  3BLT A;  1PYN A;  4KYR A;  2VEW A;  3EAX A;  3V0H A;  3AWG A;  4BJO A;  3EMU A;  3ZM2 A;  4Z6B A;  5KA0 A;  4R0S A;  4KI9 A;  5AWX A;  2SHP A;  2QEP A;  2BGD A;  3V0F A;  5KA9 A;  4QAP A;  1OEU A;  1G1H A;  2VEX A;  2CNI A;  2B49 A;  4DGX A;  1T49 A;  2I4G A;  1KAV A;  2B07 A;  3F9A A;  2DXP A;  4WU2 A;  5KA3 A;  2Q47 A;  5K23 A;  2PA5 A;  1WCH A;  2C7S A;  2H03 A;  3S3H A;  1PTU A;  5KA7 A;  2QCT A;  1G7F A;  1T48 A;  1XXP A;  4R30 A;  2RF6 A;  4NWG A;  5KAD A;  4QBE A;  4RI5 A;  1GWZ A;  1NWL A;  3ZM0 A;  1OET A;  2M3V A;  2E0T A;  4HJP A;  1OHD A;  3QCI A;  4GS0 A;  4ZRT A;  3O4T A;  3S4O A;  1YTS A;  2H4G A;  2I6O A;  1YFO A;  1Q6T A;  3CWE A;  1G4W R;  4GFU A;  3RO1 A;  3ZM3 A;  4NND A;  1PXH A;  2NTA A;  2PSZ A;  4PVG A;  3O4S A;  1G1F A;  3QCG A;  2F6F A;  1I9T A;  3N0A A;  2I4E A;  5LXQ B;  3QCH A;  4GE5 A;  3CM3 A;  1RXD A;  2CNF A;  2H4K A;  2OZ5 A;  1JLN A;  1ZCK A;  2H04 A;  4ICZ A;  4BPC A;  1AAX A;  4KYQ A;  3EZZ A;  4RKK A;  1G7G A;  5GTJ A;  2CFV A;  4Y14 A;  2HCM A;  1ZC0 A;  3QCJ A;  3QCE A;  2HNP A;  1L8K A;  4QBW A;  1ZZW A;  1C87 A;  2Y2F A;  2F6Y A;  2I6J A;  5I6V A;  5MMZ B;  3S4E A;  2QDC A;  4D3R A;  4IKC A;  4J51 A;  5KAA A;  2HC1 A;  3V0I A;  1GFY A;  3NME A;  3QCF A;  2ZN7 A;  2OC3 A;  3D1H A;  4PYH A;  1I57 A;  2HC2 A;  2MBC A;  3EB1 A;  1WRM A;  1XBO A;  4AZ1 A;  1BZC A;  4YR8 B;  1PTV A;  5BZX A;  4RDD A;  2CMB A;  1OEM X;  4QUM A;  3ZM1 A;  4GWF A;  2BV5 A;  1V3A A;  2CNG A;  4D3P A;  5J8R A;  3S3K A;  3AWF A;  2A3K A;  4ZI4 A;  4HJQ A;  3SME A;  3D44 A;  3LJ8 A;  5KAC A;  1U25 A;  2QDP A;  3I36 A;  4OHL A;  3QCD A;  1Q6S A;  2BIJ A;  2P6X A;  3MMJ A;  3QCB A;  1YTN A;  4S0G A;  3D1O A;  5IBM A;  1YPT A;  3PS5 A;  3A5J A;  2I4H A;  2QBQ A;  3B7O A;  2QBS A;  1ONY A;  5KA2 A;  2PQ5 A;  2J16 B;  4YAA A;  2QCJ A;  1U24 A;  2F6W A;  3QCN A;  4Y2E A;  3I80 A;  4HRF A;  2IMG A;  4GRY A;  1ZCL A;  2F46 A;  4ERC A;  1J4X A;  1JF7 A;  3AWE A;  3O3L A;  1MKP A;  3S3E A;  1ONZ A;  4GE6 A;  4WU3 A;  4OHH A;  1RPM A;  3QCM A;  3RGO A;  2NZ6 A;  3OMH A;  2F6Z A;  4GFV A;  2HVL A;  3D1Q A;  1PH0 A;  2CM3 A;  5KAB A;  4RH9 A;  4QAH A;  4OHE A;  5K22 A;  3I7Z A;  3M4U A;  1Q6N A;  4MBB A;  1PTY A;  1M3G A;  2BGE A;  3SR9 A;  2C46 A;  2B3O A;  2HB1 A;  1U26 A;  2OUD A;  5HDE A;  1OEO X;  2P4D A;  3MOW A;  4JBC A;  5KA8 A;  4QUN A;  1YZ4 A;  3U96 A;  2A8B A;  1YTW A;  4JNB A;  4OHD A;  3RZ2 A;  1QZ0 A;  2VEV A;  1YWF A;  3A5K A;  4D3Q A;  3O5X A;  4JMJ A;  4ZN5 A;  4DGP A;  3V0G A;  3V0E A;  4H1O A;  2BZL A;  3QCK A;  2R0B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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