1G7GA

Human ptp1b catalytic domain complexes with pnu179326
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
total genus 106
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2000-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1g7gA00
2CM7A 3EZZA 2E0TA 4OHLA 1M3GA 4BJOA 4QAPA 2Q47A 3QCCA 4NX8A 4KI9A 2CMBA 2B4PA 1Q1MA 3AWFA 3EMUA 2FJMA 2Q05A 2B4SA 4Y2EA 2QBSA 1R6HA 1G7GA 3RZ2A 1X24A 2I6IA 2CM2A 4RI4A 5KA3A 3QCHA 3V0GA 1FPRA 3H2XA 1NO6A 5EHPA 4ZI4A 4NNDA 1XXVA 1C88A 2B4UA 1BZJA 2CM3A 2VEUA 2I4HA 4ZN5A 3GXGA 2PA5A 2VEXA 4JBCA 1Q6JA 2H4GA 5HDEA 4IKCA 2PSZA 1PTVA 2GJTA 2HNPA 1U25A 1YGRA 3QCEA 3MOWA 4OHHA 2NZ6A 1D5RA 2OUDA 4R30A 1MKPA 3O5XA 2GWOA 2F71A 2NV5A 3BRHA 3GXHA 3S4EA 1ECVA 2HC1A 2SHPA 3N0AA 1OEOX 2J16B 5BZZA 1I57A 3I36A 1BZHA 2CNGA 4WTYA 3S4OA 1G1HA 4NYHA 5K25A 2F6WA 3F99A 2M3VA 2JJDA 4HJPA 1WCHA 2QBPA 2J17A 4QUNA 5KADA 2QBQA 2WGPA 1OETA 5KAAA 2H4VA 2B07A 1BZCA 4QBEA 4ICZA 2NT7A 1PYNA 2NTAA 4R0SA 2YDUA 5KA2A 1V3AA 3RGQA 2P4DA 5BX1A 2F46A 3O4SA 2G59A 1LQFA 5KA1A 3RGOA 2F6VA 1OHDA 2BZLA 1NWLA 4RH5A 2GP0A 2F6FA 3V0JA 2QDPA 4RHGA 3EU0A 2CM8A 3ZM3A 1YGUA 3NMEA 1AAXA 4ERCA 2Y2FA 2A3KA 3BM8A 4NWFA 2I6MA 5IBMA 1C83A 2VEVA 1XM2A 4GWFA 2C7SA 4JMKA 4RDDA 1PTYA 1YZ4A 3S3FA 3F9AA 5KA7A 5KA0A 2HB1A 1OEVA 1G4WR 4RH9A 3QCLA 3QKPA 1ZZWA 2CNFA 1T48A 3O3LA 2BGDA 1Q6SA 2PT0A 2HVLA 4GFVA 3EAXA 3I80A 4D3RA 1OHCA 4J51A 1C84A 2NT2A 2CNIA 4BPCA 1XXPA 2I6JA 2CJZA 1YTSA 2QCJA 3M4UA 2VEWA 3D1OA 1J4XA 2HXPA 2B49A 2I4GA 4S0GA 4QAHA 3ZM2A 1KAKA 4AZ1A 3B7OA 1PTTA 3QCIA 1PTUA 3OLRA 1L8GA 1XBOA 2BIJA 1Q6PA 5K23A 3V0HA 5LXQB 3ZM1A 3QCGA 4TVVA 4I8NA 5KABA 1VHRA 4RI5A 4JMJA 2CMCA 2ESBA 1QXKA 4GE2A 1JF7A 3D1QA 5KA8A 2HCMA 2H4KA 3D44A 1PA1A 2I5XA 1FPZA 1NNYA 2BGEA 1ONZA 2PI7A 5KA9A 4Y14A 4YAAA 3V0IA 2F6YA 2I6OA 4HJQA 5MMZB 3S3HA 1U24A 2ZN7A 1EENA 1EEOA 3ZMPA 1WRMA 2QDCA 1GWZA 1I9TA 2OOQA 2AZRA 1C86A 3QCKA 4H34A 4GRYA 3PS5A 2I3RA 3QCJA 4D3QA 1LYVA 3BLTA 3LJ8A 1T4JA 3QCBA 5M43A 2HY3A 3RO1A 1XRIA 4QBWA 3A5JA 2I75A 5J8RA 1P15A 4OHEA 3QCFA 3AWEA 2NLKA 1L8KA 1OHEA 3F9BA 3QCDA 3O4UA 1T49A 3CWEA 1WAXA 2AHSA 1NZ7A 1YFOA 1G7FA 5EHRA 5IBSA 2CFVA 3ZMQA 1Q6NA 1KAVA 2OC3A 1I9SA 3MOZA 1SUGA 2I3UA 2P6XA 2ZMMA 2QCTA 2B3OA 2VEYA 4PVGA 2QDMA 1ZC0A 4WOHA 2HNQA 2H04A 2I42A 3ZV2A 5K9WA 1GFYA 3V0DA 2G6ZA 2CMAA 4QUMA 3S3EA 4GRZA 5AWXA 2F6TA 4HRFA 2BV5A 5K9VA 3U96A 2RF6A 4YR8B 2FH7A 5I6VA 3A5KA 2Y96A 4MBBA 2CNHA 3V0EA 1YTNA 2OZ5A 4RKKA 4WU2A 5GTJA 1ZCLA 2F6ZA 1YPTA 2MBCA 4R0TA 1YWFA 1G1GA 2C46A 1OEUA 3BLUA 1ZCKA 1PA9A 3OMHA 1A5YA 4ZRTA 2F70A 2R0BA 2A8BA 2H02A 1LARA 1YN9A 4PYHA 4WU3A 2FJNA 3V0FA 4DGPA 4GS0A 1OESA 5K24A 3F41A 1QZ0A 4Z6BA 1PXHA 4NWGA 3D42A 1JLNA 1C85A 4JNBA 4B04A 1NWEA 3F81A 5KACA 1NL9A 4GE5A 3I7ZA 2I6PA 4D3PA 1FQ1A 1C87A 2DXPA 2J16A 5KA4A 3SR9A 1G4US 1U26A 3D1HA 3AWGA 2QEPA 2HC2A 4KYRA 1YTWA 5BZXA 2H03A 1PH0A 5BUGA 3QKQA 4OHDA 2I4EA 2PQ5A 3QCNA 4KYQA 2PBNA 3SMEA 1G1FA 3O4TA 3D9CA 2I1YA 3QCMA 1OEMX 2QBRA 4DGXA 2IMGA 3ZM0A 1ONYA 4OHIA 1Q6TA 3S3KA 4GFUA 1Q6MA 4GE6A 2CNEA 1RXDA 5K22A 3EB1A 4H1OA 3CM3A 3MMJA 2B4OA 1RPMA
chains in the Genus database with same CATH superfamily
2CM7A 3EZZA 1JBWA 2E0TA 4OHLA 1M3GA 4BJOA 1E8CA 4QAPA 2Q47A 3QCCA 4NX8A 4KI9A 2CMBA 3NRSA 2B4PA 1Q1MA 3AWFA 3EMUA 2FJMA 2Q05A 4BUBA 2B4SA 2WTZA 4Y2EA 2QBSA 1R6HA 1G7GA 3RZ2A 1X24A 2I6IA 2CM2A 4RI4A 5KA3A 3QCHA 3V0GA 1FPRA 3H2XA 1NO6A 5EHPA 4ZI4A 4NNDA 2AM2A 1XXVA 1JBVA 1C88A 2B4UA 1BZJA 2CM3A 2VEUA 2I4HA 4ZN5A 3GXGA 2PA5A 2VEXA 4JBCA 1Q6JA 2H4GA 5HDEA 4IKCA 2GJTA 2PSZA 1EEHA 1PTVA 1U25A 1YGRA 2HNPA 3MOWA 3QCEA 4OHHA 2UUPA 2NZ6A 1D5RA 2VTEA 2OUDA 4R30A 1MKPA 3O5XA 2GWOA 2F71A 2NV5A 3BRHA 3GXHA 3S4EA 1ECVA 2HC1A 2SHPA 3N0AA 1OEOX 4ZIYA 2J16B 5BZZA 1I57A 3I36A 1BZHA 2CNGA 4WTYA 2VTDA 2VORA 3S4OA 1G1HA 4NYHA 5K25A 2F6WA 3F99A 2M3VA 2JJDA 4HJPA 3ZM6A 1WCHA 2QBPA 2J17A 1P31A 4QUNA 2GC5A 5KADA 2QBQA 1GQQA 2WGPA 1OETA 5KAAA 2H4VA 2B07A 1BZCA 4QBEA 4ICZA 2NT7A 1PYNA 2NTAA 4R0SA 2YDUA 5KA2A 1V3AA 3RGQA 2P4DA 1W78A 5BX1A 2F46A 3O4SA 4QDIA 2G59A 1LQFA 2GCBA 5KA1A 3RGOA 2F6VA 1OHDA 2BZLA 1NWLA 4RH5A 2GP0A 2F6FA 3V0JA 2QDPA 4RHGA 3EU0A 2CM8A 3ZM3A 1YGUA 3NMEA 1AAXA 4ERCA 1J6UA 2Y2FA 2A3KA 3BM8A 4NWFA 2I6MA 5IBMA 4QF5A 1C83A 2VEVA 1XM2A 4GWFA 2C7SA 4JMKA 4RDDA 1PTYA 1GQYA 1YZ4A 3S3FA 3F9AA 5A5FA 5KA7A 2HB1A 1OEVA 5KA0A 1G4WR 4RH9A 2VOSA 2X5OA 3QCLA 3QKPA 1ZZWA 2CNFA 1T48A 3O3LA 2BGDA 1Q6SA 2PT0A 2HVLA 4GFVA 3EAXA 3I80A 4D3RA 1OHCA 4J51A 1C84A 2NT2A 2CNIA 4BPCA 1XXPA 2I6JA 2CJZA 1YTSA 2QCJA 3M4UA 2VEWA 3D1OA 1J4XA 2HXPA 2B49A 4HV4A 1E0DA 2I4GA 4S0GA 4QAHA 3ZM2A 1KAKA 4AZ1A 2XJAA 3B7OA 1PTTA 1UAGA 3QCIA 1PTUA 3LK7A 1L8GA 3OLRA 1XBOA 2BIJA 1Q6PA 5K23A 3V0HA 2XPCA 5LXQB 3ZM1A 1P3DA 3QCGA 4TVVA 4I8NA 5KABA 2Y66A 1VHRA 4RI5A 4JMJA 2CMCA 2ESBA 1QXKA 4CVKA 4GE2A 3ZM5A 1JF7A 1W7KA 3D1QA 5KA8A 2HCMA 2H4KA 3D44A 1PA1A 2JFHA 2I5XA 1FPZA 1NNYA 2BGEA 1ONZA 2GCAA 2PI7A 5KA9A 4Y14A 4YAAA 3V0IA 2F6YA 2I6OA 4HJQA 5MMZB 3S3HA 1U24A 2ZN7A 1EENA 1EEOA 3ZMPA 1WRMA 2QDCA 1GWZA 1I9TA 2OOQA 2AZRA 1C86A 3QCKA 4H34A 4GRYA 3PS5A 2I3RA 3QCJA 4D3QA 1LYVA 3BLTA 3LJ8A 2AM1A 1T4JA 3QCBA 5M43A 2HY3A 1FGSA 1XRIA 3RO1A 4QBWA 2UAGA 3A5JA 5A5EA 2I75A 2Y68A 5J8RA 1P15A 4OHEA 3QCFA 3AWEA 2NLKA 1L8KA 1OHEA 3F9BA 3QCDA 3PYZA 4CVMA 3O4UA 1T49A 3CWEA 1WAXA 2AHSA 1NZ7A 1YFOA 1G7FA 5EHRA 5IBSA 4C12A 2CFVA 3ZMQA 1Q6NA 1KAVA 2OC3A 1I9SA 3MOZA 1SUGA 2I3UA 2P6XA 2UUOA 2QCTA 2B3OA 2VEYA 2ZMMA 4PVGA 2QDMA 1ZC0A 3UAGA 4WOHA 2HNQA 2JFFA 2H04A 2I42A 3ZV2A 5K9WA 1GFYA 3V0DA 2G6ZA 2CMAA 4QUMA 3S3EA 4GRZA 5AWXA 2Y1OA 2F6TA 4HRFA 2BV5A 5K9VA 3U96A 2RF6A 4YR8B 2FH7A 5I6VA 3A5KA 2Y96A 4MBBA 2CNHA 2GC6A 3V0EA 1YTNA 2OZ5A 4RKKA 4WU2A 5GTJA 1ZCLA 2F6ZA 1YPTA 1O5ZA 2MBCA 4R0TA 2JFGA 1YWFA 1G1GA 2C46A 1OEUA 3BLUA 1ZCKA 1PA9A 3OMHA 1A5YA 4ZRTA 2F70A 2R0BA 3N2AA 2A8BA 2H02A 3ZL8A 4CVLA 1LARA 1YN9A 4PYHA 4WU3A 2FJNA 3V0FA 4DGPA 4GS0A 1OESA 5K24A 3F41A 1QZ0A 2Y67A 4Z6BA 1PXHA 3MVNA 4NWGA 3D42A 1JLNA 1C85A 4JNBA 4B04A 1NWEA 3F81A 5KACA 1NL9A 4GE5A 3I7ZA 2I6PA 4D3PA 1FQ1A 1C87A 2F00A 2DXPA 2J16A 5KA4A 3SR9A 1G4US 1U26A 3D1HA 3AWGA 2QEPA 2HC2A 4KYRA 1YTWA 4UAGA 5BZXA 1GG4A 2H03A 1PH0A 5BUGA 3QKQA 4OHDA 2I4EA 3HN7A 2PQ5A 3QCNA 4KYQA 2PBNA 3SMEA 1G1FA 3D9CA 3O4TA 2I1YA 3QCMA 2WJPA 1OEMX 2QBRA 4DGXA 2IMGA 3ZM0A 1ONYA 4OHIA 1Q6TA 3S3KA 4GFUA 1Q6MA 4BUCA 4GE6A 2CNEA 1RXDA 5K22A 3EB1A 4H1OA 3CM3A 3QCZA 3MMJA 2B4OA 4C13A 1RPMA
chains in the Genus database with same CATH topology
2CM7A 3EZZA 2E0TA 4OHLA 1M3GA 4BJOA 4QAPA 2Q47A 3QCCA 4NX8A 4KI9A 2CMBA 2B4PA 1Q1MA 3AWFA 3EMUA 2FJMA 2Q05A 2B4SA 4Y2EA 2QBSA 1R6HA 1G7GA 3RZ2A 1X24A 2I6IA 2CM2A 4RI4A 5KA3A 3QCHA 3V0GA 1FPRA 3H2XA 1NO6A 5EHPA 4ZI4A 4NNDA 1XXVA 1C88A 2B4UA 1BZJA 2CM3A 2VEUA 2I4HA 4ZN5A 3GXGA 2PA5A 2VEXA 4JBCA 1Q6JA 2H4GA 5HDEA 4IKCA 2PSZA 1PTVA 2GJTA 2HNPA 1U25A 1YGRA 3QCEA 3MOWA 4OHHA 2NZ6A 1D5RA 2OUDA 4R30A 1MKPA 3O5XA 2GWOA 2F71A 2NV5A 3BRHA 3GXHA 3S4EA 1ECVA 2HC1A 2SHPA 3N0AA 1OEOX 2J16B 5BZZA 1I57A 3I36A 1BZHA 2CNGA 4WTYA 3S4OA 1G1HA 4NYHA 5K25A 2F6WA 3F99A 2M3VA 2JJDA 4HJPA 1WCHA 2QBPA 2J17A 4QUNA 5KADA 2QBQA 2WGPA 1OETA 5KAAA 2H4VA 2B07A 1BZCA 4QBEA 4ICZA 2NT7A 1PYNA 2NTAA 4R0SA 2YDUA 5KA2A 1V3AA 3RGQA 2P4DA 5BX1A 2F46A 3O4SA 2G59A 1LQFA 5KA1A 3RGOA 2F6VA 1OHDA 2BZLA 1NWLA 4RH5A 2GP0A 2F6FA 3V0JA 2QDPA 4RHGA 3EU0A 2CM8A 3ZM3A 1YGUA 3NMEA 1AAXA 4ERCA 2Y2FA 2A3KA 3BM8A 4NWFA 2I6MA 5IBMA 1C83A 2VEVA 1XM2A 4GWFA 2C7SA 4JMKA 4RDDA 1PTYA 1YZ4A 3S3FA 3F9AA 5KA7A 5KA0A 2HB1A 1OEVA 1G4WR 4RH9A 3QCLA 3QKPA 1ZZWA 2CNFA 1T48A 3O3LA 2BGDA 1Q6SA 2PT0A 2HVLA 4GFVA 3EAXA 3I80A 4D3RA 1OHCA 4J51A 1C84A 2NT2A 2CNIA 4BPCA 1XXPA 2I6JA 2CJZA 1YTSA 2QCJA 3M4UA 2VEWA 3D1OA 1J4XA 2HXPA 2B49A 2I4GA 4S0GA 4QAHA 3ZM2A 1KAKA 4AZ1A 3B7OA 1PTTA 3QCIA 1PTUA 3OLRA 1L8GA 1XBOA 2BIJA 1Q6PA 5K23A 3V0HA 5LXQB 3ZM1A 3QCGA 4TVVA 4I8NA 5KABA 1VHRA 4RI5A 4JMJA 2CMCA 2ESBA 1QXKA 4GE2A 1JF7A 3D1QA 5KA8A 2HCMA 2H4KA 3D44A 1PA1A 2I5XA 1FPZA 1NNYA 2BGEA 1ONZA 2PI7A 5KA9A 4Y14A 4YAAA 3V0IA 2F6YA 2I6OA 4HJQA 5MMZB 3S3HA 1U24A 2ZN7A 1EENA 1EEOA 3ZMPA 1WRMA 2QDCA 1GWZA 1I9TA 2OOQA 2AZRA 1C86A 3QCKA 4H34A 4GRYA 3PS5A 2I3RA 3QCJA 4D3QA 1LYVA 3BLTA 3LJ8A 1T4JA 3QCBA 5M43A 2HY3A 3RO1A 1XRIA 4QBWA 3A5JA 2I75A 5J8RA 1P15A 4OHEA 3QCFA 3AWEA 2NLKA 1L8KA 1OHEA 3F9BA 3QCDA 3O4UA 1T49A 3CWEA 1WAXA 2AHSA 1NZ7A 1YFOA 1G7FA 5EHRA 5IBSA 2CFVA 3ZMQA 1Q6NA 1KAVA 2OC3A 1I9SA 3MOZA 1SUGA 2I3UA 2P6XA 2ZMMA 2QCTA 2B3OA 2VEYA 4PVGA 2QDMA 1ZC0A 4WOHA 2HNQA 2H04A 2I42A 3ZV2A 5K9WA 1GFYA 3V0DA 2G6ZA 2CMAA 4QUMA 3S3EA 4GRZA 5AWXA 2F6TA 4HRFA 2BV5A 5K9VA 3U96A 2RF6A 4YR8B 2FH7A 5I6VA 3A5KA 2Y96A 4MBBA 2CNHA 3V0EA 1YTNA 2OZ5A 4RKKA 4WU2A 5GTJA 1ZCLA 2F6ZA 1YPTA 2MBCA 4R0TA 1YWFA 1G1GA 2C46A 1OEUA 3BLUA 1ZCKA 1PA9A 3OMHA 1A5YA 4ZRTA 2F70A 2R0BA 2A8BA 2H02A 1LARA 1YN9A 4PYHA 4WU3A 2FJNA 3V0FA 4DGPA 4GS0A 1OESA 5K24A 3F41A 1QZ0A 4Z6BA 1PXHA 4NWGA 3D42A 1JLNA 1C85A 4JNBA 4B04A 1NWEA 3F81A 5KACA 1NL9A 4GE5A 3I7ZA 2I6PA 4D3PA 1FQ1A 1C87A 2DXPA 2J16A 5KA4A 3SR9A 1G4US 1U26A 3D1HA 3AWGA 2QEPA 2HC2A 4KYRA 1YTWA 5BZXA 2H03A 1PH0A 5BUGA 3QKQA 4OHDA 2I4EA 2PQ5A 3QCNA 4KYQA 2PBNA 3SMEA 1G1FA 3O4TA 3D9CA 2I1YA 3QCMA 1OEMX 2QBRA 4DGXA 2IMGA 3ZM0A 1ONYA 4OHIA 1Q6TA 3S3KA 4GFUA 1Q6MA 4GE6A 2CNEA 1RXDA 5K22A 3EB1A 4H1OA 3CM3A 3MMJA 2B4OA 1RPMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CM7 A;  3EZZ A;  2E0T A;  4OHL A;  1M3G A;  4BJO A;  4QAP A;  2Q47 A;  3QCC A;  4NX8 A;  4KI9 A;  2CMB A;  2B4P A;  1Q1M A;  3AWF A;  3EMU A;  2FJM A;  2Q05 A;  2B4S A;  4Y2E A;  2QBS A;  1R6H A;  1G7G A;  3RZ2 A;  1X24 A;  2I6I A;  2CM2 A;  4RI4 A;  5KA3 A;  3QCH A;  3V0G A;  1FPR A;  3H2X A;  1NO6 A;  5EHP A;  4ZI4 A;  4NND A;  1XXV A;  1C88 A;  2B4U A;  1BZJ A;  2CM3 A;  2VEU A;  2I4H A;  4ZN5 A;  3GXG A;  2PA5 A;  2VEX A;  4JBC A;  1Q6J A;  2H4G A;  5HDE A;  4IKC A;  2PSZ A;  1PTV A;  2GJT A;  2HNP A;  1U25 A;  1YGR A;  3QCE A;  3MOW A;  4OHH A;  2NZ6 A;  1D5R A;  2OUD A;  4R30 A;  1MKP A;  3O5X A;  2GWO A;  2F71 A;  2NV5 A;  3BRH A;  3GXH A;  3S4E A;  1ECV A;  2HC1 A;  2SHP A;  3N0A A;  1OEO X;  2J16 B;  5BZZ A;  1I57 A;  3I36 A;  1BZH A;  2CNG A;  4WTY A;  3S4O A;  1G1H A;  4NYH A;  5K25 A;  2F6W A;  3F99 A;  2M3V A;  2JJD A;  4HJP A;  1WCH A;  2QBP A;  2J17 A;  4QUN A;  5KAD A;  2QBQ A;  2WGP A;  1OET A;  5KAA A;  2H4V A;  2B07 A;  1BZC A;  4QBE A;  4ICZ A;  2NT7 A;  1PYN A;  2NTA A;  4R0S A;  2YDU A;  5KA2 A;  1V3A A;  3RGQ A;  2P4D A;  5BX1 A;  2F46 A;  3O4S A;  2G59 A;  1LQF A;  5KA1 A;  3RGO A;  2F6V A;  1OHD A;  2BZL A;  1NWL A;  4RH5 A;  2GP0 A;  2F6F A;  3V0J A;  2QDP A;  4RHG A;  3EU0 A;  2CM8 A;  3ZM3 A;  1YGU A;  3NME A;  1AAX A;  4ERC A;  2Y2F A;  2A3K A;  3BM8 A;  4NWF A;  2I6M A;  5IBM A;  1C83 A;  2VEV A;  1XM2 A;  4GWF A;  2C7S A;  4JMK A;  4RDD A;  1PTY A;  1YZ4 A;  3S3F A;  3F9A A;  5KA7 A;  5KA0 A;  2HB1 A;  1OEV A;  1G4W R;  4RH9 A;  3QCL A;  3QKP A;  1ZZW A;  2CNF A;  1T48 A;  3O3L A;  2BGD A;  1Q6S A;  2PT0 A;  2HVL A;  4GFV A;  3EAX A;  3I80 A;  4D3R A;  1OHC A;  4J51 A;  1C84 A;  2NT2 A;  2CNI A;  4BPC A;  1XXP A;  2I6J A;  2CJZ A;  1YTS A;  2QCJ A;  3M4U A;  2VEW A;  3D1O A;  1J4X A;  2HXP A;  2B49 A;  2I4G A;  4S0G A;  4QAH A;  3ZM2 A;  1KAK A;  4AZ1 A;  3B7O A;  1PTT A;  3QCI A;  1PTU A;  3OLR A;  1L8G A;  1XBO A;  2BIJ A;  1Q6P A;  5K23 A;  3V0H A;  5LXQ B;  3ZM1 A;  3QCG A;  4TVV A;  4I8N A;  5KAB A;  1VHR A;  4RI5 A;  4JMJ A;  2CMC A;  2ESB A;  1QXK A;  4GE2 A;  1JF7 A;  3D1Q A;  5KA8 A;  2HCM A;  2H4K A;  3D44 A;  1PA1 A;  2I5X A;  1FPZ A;  1NNY A;  2BGE A;  1ONZ A;  2PI7 A;  5KA9 A;  4Y14 A;  4YAA A;  3V0I A;  2F6Y A;  2I6O A;  4HJQ A;  5MMZ B;  3S3H A;  1U24 A;  2ZN7 A;  1EEN A;  1EEO A;  3ZMP A;  1WRM A;  2QDC A;  1GWZ A;  1I9T A;  2OOQ A;  2AZR A;  1C86 A;  3QCK A;  4H34 A;  4GRY A;  3PS5 A;  2I3R A;  3QCJ A;  4D3Q A;  1LYV A;  3BLT A;  3LJ8 A;  1T4J A;  3QCB A;  5M43 A;  2HY3 A;  3RO1 A;  1XRI A;  4QBW A;  3A5J A;  2I75 A;  5J8R A;  1P15 A;  4OHE A;  3QCF A;  3AWE A;  2NLK A;  1L8K A;  1OHE A;  3F9B A;  3QCD A;  3O4U A;  1T49 A;  3CWE A;  1WAX A;  2AHS A;  1NZ7 A;  1YFO A;  1G7F A;  5EHR A;  5IBS A;  2CFV A;  3ZMQ A;  1Q6N A;  1KAV A;  2OC3 A;  1I9S A;  3MOZ A;  1SUG A;  2I3U A;  2P6X A;  2ZMM A;  2QCT A;  2B3O A;  2VEY A;  4PVG A;  2QDM A;  1ZC0 A;  4WOH A;  2HNQ A;  2H04 A;  2I42 A;  3ZV2 A;  5K9W A;  1GFY A;  3V0D A;  2G6Z A;  2CMA A;  4QUM A;  3S3E A;  4GRZ A;  5AWX A;  2F6T A;  4HRF A;  2BV5 A;  5K9V A;  3U96 A;  2RF6 A;  4YR8 B;  2FH7 A;  5I6V A;  3A5K A;  2Y96 A;  4MBB A;  2CNH A;  3V0E A;  1YTN A;  2OZ5 A;  4RKK A;  4WU2 A;  5GTJ A;  1ZCL A;  2F6Z A;  1YPT A;  2MBC A;  4R0T A;  1YWF A;  1G1G A;  2C46 A;  1OEU A;  3BLU A;  1ZCK A;  1PA9 A;  3OMH A;  1A5Y A;  4ZRT A;  2F70 A;  2R0B A;  2A8B A;  2H02 A;  1LAR A;  1YN9 A;  4PYH A;  4WU3 A;  2FJN A;  3V0F A;  4DGP A;  4GS0 A;  1OES A;  5K24 A;  3F41 A;  1QZ0 A;  4Z6B A;  1PXH A;  4NWG A;  3D42 A;  1JLN A;  1C85 A;  4JNB A;  4B04 A;  1NWE A;  3F81 A;  5KAC A;  1NL9 A;  4GE5 A;  3I7Z A;  2I6P A;  4D3P A;  1FQ1 A;  1C87 A;  2DXP A;  2J16 A;  5KA4 A;  3SR9 A;  1G4U S;  1U26 A;  3D1H A;  3AWG A;  2QEP A;  2HC2 A;  4KYR A;  1YTW A;  5BZX A;  2H03 A;  1PH0 A;  5BUG A;  3QKQ A;  4OHD A;  2I4E A;  2PQ5 A;  3QCN A;  4KYQ A;  2PBN A;  3SME A;  1G1F A;  3O4T A;  3D9C A;  2I1Y A;  3QCM A;  1OEM X;  2QBR A;  4DGX A;  2IMG A;  3ZM0 A;  1ONY A;  4OHI A;  1Q6T A;  3S3K A;  4GFU A;  1Q6M A;  4GE6 A;  2CNE A;  1RXD A;  5K22 A;  3EB1 A;  4H1O A;  3CM3 A;  3MMJ A;  2B4O A;  1RPM A; 
#chains in the Genus database with same CATH topology
 2CM7 A;  3EZZ A;  1JBW A;  2E0T A;  4OHL A;  1M3G A;  4BJO A;  1E8C A;  4QAP A;  2Q47 A;  3QCC A;  4NX8 A;  4KI9 A;  2CMB A;  3NRS A;  2B4P A;  1Q1M A;  3AWF A;  3EMU A;  2FJM A;  2Q05 A;  4BUB A;  2B4S A;  2WTZ A;  4Y2E A;  2QBS A;  1R6H A;  1G7G A;  3RZ2 A;  1X24 A;  2I6I A;  2CM2 A;  4RI4 A;  5KA3 A;  3QCH A;  3V0G A;  1FPR A;  3H2X A;  1NO6 A;  5EHP A;  4ZI4 A;  4NND A;  2AM2 A;  1XXV A;  1JBV A;  1C88 A;  2B4U A;  1BZJ A;  2CM3 A;  2VEU A;  2I4H A;  4ZN5 A;  3GXG A;  2PA5 A;  2VEX A;  4JBC A;  1Q6J A;  2H4G A;  5HDE A;  4IKC A;  2GJT A;  2PSZ A;  1EEH A;  1PTV A;  1U25 A;  1YGR A;  2HNP A;  3MOW A;  3QCE A;  4OHH A;  2UUP A;  2NZ6 A;  1D5R A;  2VTE A;  2OUD A;  4R30 A;  1MKP A;  3O5X A;  2GWO A;  2F71 A;  2NV5 A;  3BRH A;  3GXH A;  3S4E A;  1ECV A;  2HC1 A;  2SHP A;  3N0A A;  1OEO X;  4ZIY A;  2J16 B;  5BZZ A;  1I57 A;  3I36 A;  1BZH A;  2CNG A;  4WTY A;  2VTD A;  2VOR A;  3S4O A;  1G1H A;  4NYH A;  5K25 A;  2F6W A;  3F99 A;  2M3V A;  2JJD A;  4HJP A;  3ZM6 A;  1WCH A;  2QBP A;  2J17 A;  1P31 A;  4QUN A;  2GC5 A;  5KAD A;  2QBQ A;  1GQQ A;  2WGP A;  1OET A;  5KAA A;  2H4V A;  2B07 A;  1BZC A;  4QBE A;  4ICZ A;  2NT7 A;  1PYN A;  2NTA A;  4R0S A;  2YDU A;  5KA2 A;  1V3A A;  3RGQ A;  2P4D A;  1W78 A;  5BX1 A;  2F46 A;  3O4S A;  4QDI A;  2G59 A;  1LQF A;  2GCB A;  5KA1 A;  3RGO A;  2F6V A;  1OHD A;  2BZL A;  1NWL A;  4RH5 A;  2GP0 A;  2F6F A;  3V0J A;  2QDP A;  4RHG A;  3EU0 A;  2CM8 A;  3ZM3 A;  1YGU A;  3NME A;  1AAX A;  4ERC A;  1J6U A;  2Y2F A;  2A3K A;  3BM8 A;  4NWF A;  2I6M A;  5IBM A;  4QF5 A;  1C83 A;  2VEV A;  1XM2 A;  4GWF A;  2C7S A;  4JMK A;  4RDD A;  1PTY A;  1GQY A;  1YZ4 A;  3S3F A;  3F9A A;  5A5F A;  5KA7 A;  2HB1 A;  1OEV A;  5KA0 A;  1G4W R;  4RH9 A;  2VOS A;  2X5O A;  3QCL A;  3QKP A;  1ZZW A;  2CNF A;  1T48 A;  3O3L A;  2BGD A;  1Q6S A;  2PT0 A;  2HVL A;  4GFV A;  3EAX A;  3I80 A;  4D3R A;  1OHC A;  4J51 A;  1C84 A;  2NT2 A;  2CNI A;  4BPC A;  1XXP A;  2I6J A;  2CJZ A;  1YTS A;  2QCJ A;  3M4U A;  2VEW A;  3D1O A;  1J4X A;  2HXP A;  2B49 A;  4HV4 A;  1E0D A;  2I4G A;  4S0G A;  4QAH A;  3ZM2 A;  1KAK A;  4AZ1 A;  2XJA A;  3B7O A;  1PTT A;  1UAG A;  3QCI A;  1PTU A;  3LK7 A;  1L8G A;  3OLR A;  1XBO A;  2BIJ A;  1Q6P A;  5K23 A;  3V0H A;  2XPC A;  5LXQ B;  3ZM1 A;  1P3D A;  3QCG A;  4TVV A;  4I8N A;  5KAB A;  2Y66 A;  1VHR A;  4RI5 A;  4JMJ A;  2CMC A;  2ESB A;  1QXK A;  4CVK A;  4GE2 A;  3ZM5 A;  1JF7 A;  1W7K A;  3D1Q A;  5KA8 A;  2HCM A;  2H4K A;  3D44 A;  1PA1 A;  2JFH A;  2I5X A;  1FPZ A;  1NNY A;  2BGE A;  1ONZ A;  2GCA A;  2PI7 A;  5KA9 A;  4Y14 A;  4YAA A;  3V0I A;  2F6Y A;  2I6O A;  4HJQ A;  5MMZ B;  3S3H A;  1U24 A;  2ZN7 A;  1EEN A;  1EEO A;  3ZMP A;  1WRM A;  2QDC A;  1GWZ A;  1I9T A;  2OOQ A;  2AZR A;  1C86 A;  3QCK A;  4H34 A;  4GRY A;  3PS5 A;  2I3R A;  3QCJ A;  4D3Q A;  1LYV A;  3BLT A;  3LJ8 A;  2AM1 A;  1T4J A;  3QCB A;  5M43 A;  2HY3 A;  1FGS A;  1XRI A;  3RO1 A;  4QBW A;  2UAG A;  3A5J A;  5A5E A;  2I75 A;  2Y68 A;  5J8R A;  1P15 A;  4OHE A;  3QCF A;  3AWE A;  2NLK A;  1L8K A;  1OHE A;  3F9B A;  3QCD A;  3PYZ A;  4CVM A;  3O4U A;  1T49 A;  3CWE A;  1WAX A;  2AHS A;  1NZ7 A;  1YFO A;  1G7F A;  5EHR A;  5IBS A;  4C12 A;  2CFV A;  3ZMQ A;  1Q6N A;  1KAV A;  2OC3 A;  1I9S A;  3MOZ A;  1SUG A;  2I3U A;  2P6X A;  2UUO A;  2QCT A;  2B3O A;  2VEY A;  2ZMM A;  4PVG A;  2QDM A;  1ZC0 A;  3UAG A;  4WOH A;  2HNQ A;  2JFF A;  2H04 A;  2I42 A;  3ZV2 A;  5K9W A;  1GFY A;  3V0D A;  2G6Z A;  2CMA A;  4QUM A;  3S3E A;  4GRZ A;  5AWX A;  2Y1O A;  2F6T A;  4HRF A;  2BV5 A;  5K9V A;  3U96 A;  2RF6 A;  4YR8 B;  2FH7 A;  5I6V A;  3A5K A;  2Y96 A;  4MBB A;  2CNH A;  2GC6 A;  3V0E A;  1YTN A;  2OZ5 A;  4RKK A;  4WU2 A;  5GTJ A;  1ZCL A;  2F6Z A;  1YPT A;  1O5Z A;  2MBC A;  4R0T A;  2JFG A;  1YWF A;  1G1G A;  2C46 A;  1OEU A;  3BLU A;  1ZCK A;  1PA9 A;  3OMH A;  1A5Y A;  4ZRT A;  2F70 A;  2R0B A;  3N2A A;  2A8B A;  2H02 A;  3ZL8 A;  4CVL A;  1LAR A;  1YN9 A;  4PYH A;  4WU3 A;  2FJN A;  3V0F A;  4DGP A;  4GS0 A;  1OES A;  5K24 A;  3F41 A;  1QZ0 A;  2Y67 A;  4Z6B A;  1PXH A;  3MVN A;  4NWG A;  3D42 A;  1JLN A;  1C85 A;  4JNB A;  4B04 A;  1NWE A;  3F81 A;  5KAC A;  1NL9 A;  4GE5 A;  3I7Z A;  2I6P A;  4D3P A;  1FQ1 A;  1C87 A;  2F00 A;  2DXP A;  2J16 A;  5KA4 A;  3SR9 A;  1G4U S;  1U26 A;  3D1H A;  3AWG A;  2QEP A;  2HC2 A;  4KYR A;  1YTW A;  4UAG A;  5BZX A;  1GG4 A;  2H03 A;  1PH0 A;  5BUG A;  3QKQ A;  4OHD A;  2I4E A;  3HN7 A;  2PQ5 A;  3QCN A;  4KYQ A;  2PBN A;  3SME A;  1G1F A;  3D9C A;  3O4T A;  2I1Y A;  3QCM A;  2WJP A;  1OEM X;  2QBR A;  4DGX A;  2IMG A;  3ZM0 A;  1ONY A;  4OHI A;  1Q6T A;  3S3K A;  4GFU A;  1Q6M A;  4BUC A;  4GE6 A;  2CNE A;  1RXD A;  5K22 A;  3EB1 A;  4H1O A;  3CM3 A;  3QCZ A;  3MMJ A;  2B4O A;  4C13 A;  1RPM A; 
#chains in the Genus database with same CATH homology
 2CM7 A;  3EZZ A;  2E0T A;  4OHL A;  1M3G A;  4BJO A;  4QAP A;  2Q47 A;  3QCC A;  4NX8 A;  4KI9 A;  2CMB A;  2B4P A;  1Q1M A;  3AWF A;  3EMU A;  2FJM A;  2Q05 A;  2B4S A;  4Y2E A;  2QBS A;  1R6H A;  1G7G A;  3RZ2 A;  1X24 A;  2I6I A;  2CM2 A;  4RI4 A;  5KA3 A;  3QCH A;  3V0G A;  1FPR A;  3H2X A;  1NO6 A;  5EHP A;  4ZI4 A;  4NND A;  1XXV A;  1C88 A;  2B4U A;  1BZJ A;  2CM3 A;  2VEU A;  2I4H A;  4ZN5 A;  3GXG A;  2PA5 A;  2VEX A;  4JBC A;  1Q6J A;  2H4G A;  5HDE A;  4IKC A;  2PSZ A;  1PTV A;  2GJT A;  2HNP A;  1U25 A;  1YGR A;  3QCE A;  3MOW A;  4OHH A;  2NZ6 A;  1D5R A;  2OUD A;  4R30 A;  1MKP A;  3O5X A;  2GWO A;  2F71 A;  2NV5 A;  3BRH A;  3GXH A;  3S4E A;  1ECV A;  2HC1 A;  2SHP A;  3N0A A;  1OEO X;  2J16 B;  5BZZ A;  1I57 A;  3I36 A;  1BZH A;  2CNG A;  4WTY A;  3S4O A;  1G1H A;  4NYH A;  5K25 A;  2F6W A;  3F99 A;  2M3V A;  2JJD A;  4HJP A;  1WCH A;  2QBP A;  2J17 A;  4QUN A;  5KAD A;  2QBQ A;  2WGP A;  1OET A;  5KAA A;  2H4V A;  2B07 A;  1BZC A;  4QBE A;  4ICZ A;  2NT7 A;  1PYN A;  2NTA A;  4R0S A;  2YDU A;  5KA2 A;  1V3A A;  3RGQ A;  2P4D A;  5BX1 A;  2F46 A;  3O4S A;  2G59 A;  1LQF A;  5KA1 A;  3RGO A;  2F6V A;  1OHD A;  2BZL A;  1NWL A;  4RH5 A;  2GP0 A;  2F6F A;  3V0J A;  2QDP A;  4RHG A;  3EU0 A;  2CM8 A;  3ZM3 A;  1YGU A;  3NME A;  1AAX A;  4ERC A;  2Y2F A;  2A3K A;  3BM8 A;  4NWF A;  2I6M A;  5IBM A;  1C83 A;  2VEV A;  1XM2 A;  4GWF A;  2C7S A;  4JMK A;  4RDD A;  1PTY A;  1YZ4 A;  3S3F A;  3F9A A;  5KA7 A;  5KA0 A;  2HB1 A;  1OEV A;  1G4W R;  4RH9 A;  3QCL A;  3QKP A;  1ZZW A;  2CNF A;  1T48 A;  3O3L A;  2BGD A;  1Q6S A;  2PT0 A;  2HVL A;  4GFV A;  3EAX A;  3I80 A;  4D3R A;  1OHC A;  4J51 A;  1C84 A;  2NT2 A;  2CNI A;  4BPC A;  1XXP A;  2I6J A;  2CJZ A;  1YTS A;  2QCJ A;  3M4U A;  2VEW A;  3D1O A;  1J4X A;  2HXP A;  2B49 A;  2I4G A;  4S0G A;  4QAH A;  3ZM2 A;  1KAK A;  4AZ1 A;  3B7O A;  1PTT A;  3QCI A;  1PTU A;  3OLR A;  1L8G A;  1XBO A;  2BIJ A;  1Q6P A;  5K23 A;  3V0H A;  5LXQ B;  3ZM1 A;  3QCG A;  4TVV A;  4I8N A;  5KAB A;  1VHR A;  4RI5 A;  4JMJ A;  2CMC A;  2ESB A;  1QXK A;  4GE2 A;  1JF7 A;  3D1Q A;  5KA8 A;  2HCM A;  2H4K A;  3D44 A;  1PA1 A;  2I5X A;  1FPZ A;  1NNY A;  2BGE A;  1ONZ A;  2PI7 A;  5KA9 A;  4Y14 A;  4YAA A;  3V0I A;  2F6Y A;  2I6O A;  4HJQ A;  5MMZ B;  3S3H A;  1U24 A;  2ZN7 A;  1EEN A;  1EEO A;  3ZMP A;  1WRM A;  2QDC A;  1GWZ A;  1I9T A;  2OOQ A;  2AZR A;  1C86 A;  3QCK A;  4H34 A;  4GRY A;  3PS5 A;  2I3R A;  3QCJ A;  4D3Q A;  1LYV A;  3BLT A;  3LJ8 A;  1T4J A;  3QCB A;  5M43 A;  2HY3 A;  3RO1 A;  1XRI A;  4QBW A;  3A5J A;  2I75 A;  5J8R A;  1P15 A;  4OHE A;  3QCF A;  3AWE A;  2NLK A;  1L8K A;  1OHE A;  3F9B A;  3QCD A;  3O4U A;  1T49 A;  3CWE A;  1WAX A;  2AHS A;  1NZ7 A;  1YFO A;  1G7F A;  5EHR A;  5IBS A;  2CFV A;  3ZMQ A;  1Q6N A;  1KAV A;  2OC3 A;  1I9S A;  3MOZ A;  1SUG A;  2I3U A;  2P6X A;  2ZMM A;  2QCT A;  2B3O A;  2VEY A;  4PVG A;  2QDM A;  1ZC0 A;  4WOH A;  2HNQ A;  2H04 A;  2I42 A;  3ZV2 A;  5K9W A;  1GFY A;  3V0D A;  2G6Z A;  2CMA A;  4QUM A;  3S3E A;  4GRZ A;  5AWX A;  2F6T A;  4HRF A;  2BV5 A;  5K9V A;  3U96 A;  2RF6 A;  4YR8 B;  2FH7 A;  5I6V A;  3A5K A;  2Y96 A;  4MBB A;  2CNH A;  3V0E A;  1YTN A;  2OZ5 A;  4RKK A;  4WU2 A;  5GTJ A;  1ZCL A;  2F6Z A;  1YPT A;  2MBC A;  4R0T A;  1YWF A;  1G1G A;  2C46 A;  1OEU A;  3BLU A;  1ZCK A;  1PA9 A;  3OMH A;  1A5Y A;  4ZRT A;  2F70 A;  2R0B A;  2A8B A;  2H02 A;  1LAR A;  1YN9 A;  4PYH A;  4WU3 A;  2FJN A;  3V0F A;  4DGP A;  4GS0 A;  1OES A;  5K24 A;  3F41 A;  1QZ0 A;  4Z6B A;  1PXH A;  4NWG A;  3D42 A;  1JLN A;  1C85 A;  4JNB A;  4B04 A;  1NWE A;  3F81 A;  5KAC A;  1NL9 A;  4GE5 A;  3I7Z A;  2I6P A;  4D3P A;  1FQ1 A;  1C87 A;  2DXP A;  2J16 A;  5KA4 A;  3SR9 A;  1G4U S;  1U26 A;  3D1H A;  3AWG A;  2QEP A;  2HC2 A;  4KYR A;  1YTW A;  5BZX A;  2H03 A;  1PH0 A;  5BUG A;  3QKQ A;  4OHD A;  2I4E A;  2PQ5 A;  3QCN A;  4KYQ A;  2PBN A;  3SME A;  1G1F A;  3O4T A;  3D9C A;  2I1Y A;  3QCM A;  1OEM X;  2QBR A;  4DGX A;  2IMG A;  3ZM0 A;  1ONY A;  4OHI A;  1Q6T A;  3S3K A;  4GFU A;  1Q6M A;  4GE6 A;  2CNE A;  1RXD A;  5K22 A;  3EB1 A;  4H1O A;  3CM3 A;  3MMJ A;  2B4O A;  1RPM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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