1GWZA

Crystal structure of the catalytic domain of the protein tyrosine phosphatase shp-1
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
283
structure length
280
Chain Sequence
FESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords SHP-1
total genus 69
structure length 280
sequence length 283
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 1998-08-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1gwzA00
2I4EA 4QUMA 4R0SA 1JF7A 2B3OA 4R30A 3BM8A 5BUGA 4GE2A 2HXPA 4BPCA 2I6JA 3CM3A 5K9WA 3EZZA 1ZCLA 4WOHA 1ZZWA 3D1HA 3D1OA 1Q6PA 2F46A 1I9SA 2VEYA 1RXDA 1KAVA 2Q05A 2QDCA 3A5KA 2CFVA 2G6ZA 5MMZB 2IMGA 5K9VA 4QBWA 3S3EA 5J8RA 2J16B 3EAXA 2B4SA 4ERCA 1YGUA 5AWXA 4HRFA 1XM2A 4JBCA 1YTNA 1QXKA 1XXPA 1C84A 3D1QA 2J16A 2F6ZA 2I6IA 5K22A 4GS0A 3QCJA 4D3RA 5K25A 4ZN5A 3F99A 1U25A 2AHSA 4HJPA 1QZ0A 2A3KA 4HJQA 3SMEA 4KYRA 3RO1A 1MKPA 2MBCA 2BV5A 2QCTA 3QCGA 4TVVA 4IKCA 2WGPA 3V0GA 4YAAA 2GJTA 1PYNA 2CM2A 1OHCA 1G1GA 2B4PA 1Q6SA 3MOZA 5BZXA 2VEWA 2I3UA 1C88A 1EENA 1NL9A 5EHPA 1YPTA 2F6VA 4ICZA 4RHGA 4RH9A 4DGPA 3QCNA 2I3RA 1M3GA 3I80A 2JJDA 2E0TA 1J4XA 4Y2EA 2PSZA 2GWOA 3QCBA 2P4DA 4D3PA 4NWGA 1L8KA 3O3LA 3BLUA 3S4EA 2H4VA 3QCDA 1OEMX 5KA0A 2CNHA 1ONZA 4NWFA 2VEUA 3O4TA 3RGQA 2ZN7A 2A8BA 1I9TA 5LXQB 4KYQA 2OUDA 1YN9A 2NT7A 5KA8A 3QCLA 5K24A 4PYHA 1PA1A 2NV5A 3MOWA 4I8NA 3V0DA 2F71A 5M43A 1BZJA 5KA1A 2QBQA 3OLRA 2B4UA 2DXPA 3NMEA 2I4HA 2NLKA 1OEOX 3EU0A 4RI4A 1FQ1A 5HDEA 1ZCKA 4OHLA 3BRHA 1Q6MA 2PBNA 4JMKA 2CNFA 5IBSA 1VHRA 2AZRA 3I7ZA 4AZ1A 1XBOA 1Q6TA 2NZ6A 2B49A 3AWGA 2QCJA 4ZI4A 3N0AA 4QBEA 3QCHA 5I6VA 2OZ5A 2BZLA 2VEXA 2I5XA 1PTTA 1I57A 2J17A 3GXHA 2HCMA 1C85A 1YGRA 3V0EA 2B07A 3PS5A 2G59A 2M3VA 2HC2A 2Y2FA 3S3HA 2F6TA 1A5YA 1L8GA 1NNYA 1YWFA 1OEUA 3QKQA 1OESA 1ZC0A 2QBSA 1YFOA 1OHEA 2OOQA 4MBBA 4OHIA 4WU2A 2PT0A 3RGOA 4RI5A 1LQFA 2F6YA 1P15A 5BX1A 1LYVA 5GTJA 2NT2A 1XRIA 1WCHA 4GWFA 4Z6BA 5EHRA 3V0FA 1T48A 2C46A 4OHHA 4J51A 2CM3A 2GP0A 1G4WR 5IBMA 2YDUA 1Q6NA 1G7GA 3EMUA 4QUNA 2FH7A 1OHDA 3D9CA 1JLNA 3ZM2A 1Q1MA 1ECVA 2CNIA 3AWFA 2VEVA 1SUGA 3I36A 2SHPA 3B7OA 4GE6A 1AAXA 3O4SA 2HVLA 2QEPA 4H34A 4GFUA 4JNBA 2OC3A 3ZV2A 1NZ7A 1ONYA 3ZMPA 2PA5A 3EB1A 2CNGA 2RF6A 5KADA 2H02A 1GWZA 3BLTA 3SR9A 3D44A 3O4UA 4GE5A 1T49A 3S3KA 1G4US 2BIJA 4QAPA 2NTAA 3V0JA 5KACA 4YR8B 5KA4A 2QDPA 3ZM3A 1WAXA 3V0IA 3RZ2A 4D3QA 1BZCA 1NWEA 3F81A 3F9BA 2I6MA 4DGXA 4R0TA 3OMHA 1GFYA 2ESBA 3A5JA 1PTUA 2CM8A 4QAHA 3F41A 2H03A 3CWEA 2F70A 1BZHA 2CNEA 4WTYA 5KAAA 4OHDA 2I6OA 2CJZA 2I4GA 2P6XA 2PI7A 2I6PA 2I42A 4OHEA 3QCCA 1C83A 2PQ5A 1U24A 2QBPA 4RKKA 4PVGA 4NYHA 1OEVA 5K23A 1U26A 2ZMMA 4KI9A 4S0GA 3QCMA 2H04A 3U96A 3GXGA 3LJ8A 1YTWA 2CMBA 2BGEA 2HC1A 4BJOA 2H4KA 3AWEA 4ZRTA 1NWLA 4RDDA 2HB1A 1LARA 2HY3A 3H2XA 3D42A 1KAKA 2Y96A 1R6HA 1YZ4A 1PA9A 2BGDA 1PTVA 4B04A 3ZM0A 4JMJA 4GRYA 1T4JA 5KA3A 1G7FA 2HNQA 1RPMA 1NO6A 3S4OA 2R0BA 1X24A 3QKPA 2H4GA 4GFVA 3F9AA 2F6WA 2QBRA 2F6FA 1YTSA 1G1HA 1OETA 3S3FA 1FPRA 3QCKA 5KABA 3O5XA 1D5RA 4NNDA 1FPZA 2FJMA 1C86A 2I75A 3QCIA 2Q47A 4WU3A 1V3AA 1PH0A 3ZMQA 5KA2A 2C7SA 1XXVA 2CMCA 3QCFA 1EEOA 1WRMA 2HNPA 3QCEA 5BZZA 1C87A 1Q6JA 2FJNA 3V0HA 5KA7A 4RH5A 2CMAA 4NX8A 1G1FA 2CM7A 2I1YA 1PTYA 1PXHA 3MMJA 4GRZA 2B4OA 4Y14A 3ZM1A 5KA9A 2QDMA 3M4UA 4H1OA
chains in the Genus database with same CATH superfamily
2I4EA 4QUMA 4R0SA 5A5FA 1JF7A 2JFGA 2B3OA 4R30A 3BM8A 5BUGA 4GE2A 2HXPA 4BPCA 2I6JA 3CM3A 5K9WA 3EZZA 1ZCLA 4WOHA 1ZZWA 3D1HA 3D1OA 1Q6PA 2F46A 1I9SA 2VEYA 2UUPA 3A5KA 1RXDA 1KAVA 2Q05A 2QDCA 1E8CA 2CFVA 2G6ZA 5MMZB 2IMGA 5K9VA 2JFFA 4QBWA 1GQYA 3S3EA 2Y67A 5J8RA 2J16B 3EAXA 2B4SA 4ERCA 1YGUA 5AWXA 4HRFA 1XM2A 4JBCA 1YTNA 1QXKA 1XXPA 1C84A 3D1QA 2J16A 2F6ZA 2I6IA 5K22A 4GS0A 3QCJA 4D3RA 5K25A 4ZN5A 3F99A 1U25A 2AHSA 4HJPA 1QZ0A 2A3KA 3UAGA 4HJQA 3SMEA 4KYRA 3RO1A 1MKPA 2MBCA 2BV5A 2QCTA 2X5OA 3QCGA 4TVVA 4IKCA 2WGPA 3V0GA 4YAAA 2GJTA 1PYNA 2CM2A 1OHCA 1G1GA 2B4PA 1Q6SA 3MOZA 5BZXA 2VEWA 2I3UA 1C88A 1EENA 1NL9A 5EHPA 2WJPA 1YPTA 2F6VA 4ICZA 4RHGA 4RH9A 4DGPA 3QCNA 2I3RA 1M3GA 3I80A 2GCAA 2VTDA 2JJDA 2Y1OA 2E0TA 1J4XA 4Y2EA 2Y66A 2PSZA 2GWOA 3QCBA 2P4DA 4D3PA 1O5ZA 4NWGA 1L8KA 3O3LA 2XPCA 3BLUA 3S4EA 2H4VA 3QCDA 1OEMX 5KA0A 2CNHA 1ONZA 4NWFA 2VEUA 3O4TA 3RGQA 2ZN7A 3ZM5A 2A8BA 1J6UA 1I9TA 5LXQB 3HN7A 4KYQA 2OUDA 1YN9A 2NT7A 5KA8A 3QCLA 5K24A 4PYHA 1PA1A 2NV5A 3MOWA 4I8NA 3V0DA 2F71A 5M43A 1BZJA 5KA1A 2QBQA 3OLRA 2B4UA 2DXPA 3NMEA 2I4HA 1JBVA 2NLKA 1OEOX 3EU0A 4RI4A 1FQ1A 5HDEA 1ZCKA 4OHLA 2Y68A 2GC6A 3BRHA 1Q6MA 2PBNA 4JMKA 2CNFA 5IBSA 1VHRA 2AZRA 3I7ZA 4AZ1A 1XBOA 1Q6TA 2NZ6A 2B49A 3AWGA 2QCJA 4ZI4A 2F00A 4HV4A 2VTEA 3N0AA 4QBEA 3QCHA 5I6VA 2OZ5A 2BZLA 2VEXA 2I5XA 1PTTA 1I57A 2J17A 3GXHA 2HCMA 1C85A 1YGRA 4CVMA 3V0EA 2B07A 3PS5A 2GCBA 2G59A 2M3VA 2HC2A 4BUCA 2Y2FA 3S3HA 2F6TA 1A5YA 1L8GA 1NNYA 1YWFA 2AM1A 1OEUA 3QKQA 1OESA 1ZC0A 2QBSA 1YFOA 1OHEA 2OOQA 4MBBA 4OHIA 4WU2A 2PT0A 3RGOA 4BUBA 4RI5A 1LQFA 2F6YA 1P15A 5BX1A 1LYVA 5GTJA 4CVKA 2NT2A 1XRIA 1WCHA 4GWFA 4Z6BA 5EHRA 2AM2A 3V0FA 1T48A 2C46A 4OHHA 4J51A 2CM3A 2GP0A 1G4WR 5IBMA 3N2AA 2YDUA 1Q6NA 1G7GA 3EMUA 4CVLA 4QUNA 2FH7A 4C13A 1OHDA 1UAGA 3D9CA 1JLNA 3ZM2A 1Q1MA 1ECVA 2CNIA 3AWFA 2UAGA 1GQQA 2VEVA 1SUGA 1P31A 3I36A 2SHPA 3B7OA 4GE6A 1AAXA 3O4SA 2HVLA 2QEPA 2XJAA 3PYZA 4H34A 1W78A 4GFUA 2OC3A 4JNBA 1P3DA 3ZV2A 1NZ7A 1ONYA 5A5EA 3ZMPA 2VORA 2PA5A 3EB1A 2CNGA 2RF6A 4QF5A 5KADA 2H02A 2UUOA 1FGSA 3BLTA 1GWZA 2WTZA 3SR9A 3D44A 3O4UA 4GE5A 1T49A 3S3KA 1G4US 2BIJA 4QAPA 4UAGA 2NTAA 3V0JA 5KACA 4YR8B 1W7KA 2QDPA 5KA4A 3ZM3A 1WAXA 3V0IA 3RZ2A 4D3QA 1BZCA 1NWEA 3F81A 3F9BA 2I6MA 2GC5A 4DGXA 4C12A 4R0TA 3OMHA 1GFYA 2ESBA 3A5JA 1PTUA 2CM8A 4QAHA 3F41A 2H03A 3NRSA 3CWEA 2F70A 1BZHA 2CNEA 4WTYA 5KAAA 4OHDA 2I6OA 2CJZA 2I4GA 2P6XA 2PI7A 2I42A 2I6PA 4OHEA 3QCCA 1C83A 2PQ5A 1U24A 3ZM6A 2QBPA 4RKKA 4PVGA 4NYHA 1OEVA 5K23A 1U26A 2ZMMA 4KI9A 4S0GA 3QCMA 3MVNA 2H04A 3U96A 3GXGA 3LK7A 3LJ8A 1JBWA 1YTWA 2CMBA 2BGEA 2HC1A 4BJOA 2H4KA 3AWEA 4ZRTA 1NWLA 4RDDA 2HB1A 1LARA 2JFHA 2HY3A 3H2XA 3D42A 1KAKA 2Y96A 1R6HA 1YZ4A 1PA9A 2BGDA 1PTVA 4B04A 3ZM0A 4JMJA 4GRYA 4QDIA 3ZL8A 1T4JA 5KA3A 1G7FA 2HNQA 1RPMA 1NO6A 3S4OA 2R0BA 1X24A 3QKPA 2H4GA 4GFVA 3F9AA 2F6WA 2QBRA 2F6FA 1YTSA 1G1HA 1OETA 3S3FA 1FPRA 3QCKA 5KABA 3O5XA 1D5RA 2VOSA 4NNDA 1E0DA 1FPZA 2FJMA 1C86A 2I75A 3QCIA 2Q47A 4WU3A 1V3AA 1PH0A 3ZMQA 5KA2A 3QCZA 2C7SA 1XXVA 2CMCA 3QCFA 1EEOA 1WRMA 2HNPA 3QCEA 1GG4A 5BZZA 1C87A 1Q6JA 1EEHA 2FJNA 4ZIYA 3V0HA 5KA7A 4RH5A 2CMAA 4NX8A 1G1FA 2CM7A 2I1YA 1PTYA 1PXHA 3MMJA 4GRZA 2B4OA 4Y14A 3ZM1A 5KA9A 2QDMA 3M4UA 4H1OA
chains in the Genus database with same CATH topology
2I4EA 4QUMA 4R0SA 1JF7A 2B3OA 4R30A 3BM8A 5BUGA 4GE2A 2HXPA 4BPCA 2I6JA 3CM3A 5K9WA 3EZZA 1ZCLA 4WOHA 1ZZWA 3D1HA 3D1OA 1Q6PA 2F46A 1I9SA 2VEYA 1RXDA 1KAVA 2Q05A 2QDCA 3A5KA 2CFVA 2G6ZA 5MMZB 2IMGA 5K9VA 4QBWA 3S3EA 5J8RA 2J16B 3EAXA 2B4SA 4ERCA 1YGUA 5AWXA 4HRFA 1XM2A 4JBCA 1YTNA 1QXKA 1XXPA 1C84A 3D1QA 2J16A 2F6ZA 2I6IA 5K22A 4GS0A 3QCJA 4D3RA 5K25A 4ZN5A 3F99A 1U25A 2AHSA 4HJPA 1QZ0A 2A3KA 4HJQA 3SMEA 4KYRA 3RO1A 1MKPA 2MBCA 2BV5A 2QCTA 3QCGA 4TVVA 4IKCA 2WGPA 3V0GA 4YAAA 2GJTA 1PYNA 2CM2A 1OHCA 1G1GA 2B4PA 1Q6SA 3MOZA 5BZXA 2VEWA 2I3UA 1C88A 1EENA 1NL9A 5EHPA 1YPTA 2F6VA 4ICZA 4RHGA 4RH9A 4DGPA 3QCNA 2I3RA 1M3GA 3I80A 2JJDA 2E0TA 1J4XA 4Y2EA 2PSZA 2GWOA 3QCBA 2P4DA 4D3PA 4NWGA 1L8KA 3O3LA 3BLUA 3S4EA 2H4VA 3QCDA 1OEMX 5KA0A 2CNHA 1ONZA 4NWFA 2VEUA 3O4TA 3RGQA 2ZN7A 2A8BA 1I9TA 5LXQB 4KYQA 2OUDA 1YN9A 2NT7A 5KA8A 3QCLA 5K24A 4PYHA 1PA1A 2NV5A 3MOWA 4I8NA 3V0DA 2F71A 5M43A 1BZJA 5KA1A 2QBQA 3OLRA 2B4UA 2DXPA 3NMEA 2I4HA 2NLKA 1OEOX 3EU0A 4RI4A 1FQ1A 5HDEA 1ZCKA 4OHLA 3BRHA 1Q6MA 2PBNA 4JMKA 2CNFA 5IBSA 1VHRA 2AZRA 3I7ZA 4AZ1A 1XBOA 1Q6TA 2NZ6A 2B49A 3AWGA 2QCJA 4ZI4A 3N0AA 4QBEA 3QCHA 5I6VA 2OZ5A 2BZLA 2VEXA 2I5XA 1PTTA 1I57A 2J17A 3GXHA 2HCMA 1C85A 1YGRA 3V0EA 2B07A 3PS5A 2G59A 2M3VA 2HC2A 2Y2FA 3S3HA 2F6TA 1A5YA 1L8GA 1NNYA 1YWFA 1OEUA 3QKQA 1OESA 1ZC0A 2QBSA 1YFOA 1OHEA 2OOQA 4MBBA 4OHIA 4WU2A 2PT0A 3RGOA 4RI5A 1LQFA 2F6YA 1P15A 5BX1A 1LYVA 5GTJA 2NT2A 1XRIA 1WCHA 4GWFA 4Z6BA 5EHRA 3V0FA 1T48A 2C46A 4OHHA 4J51A 2CM3A 2GP0A 1G4WR 5IBMA 2YDUA 1Q6NA 1G7GA 3EMUA 4QUNA 2FH7A 1OHDA 3D9CA 1JLNA 3ZM2A 1Q1MA 1ECVA 2CNIA 3AWFA 2VEVA 1SUGA 3I36A 2SHPA 3B7OA 4GE6A 1AAXA 3O4SA 2HVLA 2QEPA 4H34A 4GFUA 4JNBA 2OC3A 3ZV2A 1NZ7A 1ONYA 3ZMPA 2PA5A 3EB1A 2CNGA 2RF6A 5KADA 2H02A 1GWZA 3BLTA 3SR9A 3D44A 3O4UA 4GE5A 1T49A 3S3KA 1G4US 2BIJA 4QAPA 2NTAA 3V0JA 5KACA 4YR8B 5KA4A 2QDPA 3ZM3A 1WAXA 3V0IA 3RZ2A 4D3QA 1BZCA 1NWEA 3F81A 3F9BA 2I6MA 4DGXA 4R0TA 3OMHA 1GFYA 2ESBA 3A5JA 1PTUA 2CM8A 4QAHA 3F41A 2H03A 3CWEA 2F70A 1BZHA 2CNEA 4WTYA 5KAAA 4OHDA 2I6OA 2CJZA 2I4GA 2P6XA 2PI7A 2I6PA 2I42A 4OHEA 3QCCA 1C83A 2PQ5A 1U24A 2QBPA 4RKKA 4PVGA 4NYHA 1OEVA 5K23A 1U26A 2ZMMA 4KI9A 4S0GA 3QCMA 2H04A 3U96A 3GXGA 3LJ8A 1YTWA 2CMBA 2BGEA 2HC1A 4BJOA 2H4KA 3AWEA 4ZRTA 1NWLA 4RDDA 2HB1A 1LARA 2HY3A 3H2XA 3D42A 1KAKA 2Y96A 1R6HA 1YZ4A 1PA9A 2BGDA 1PTVA 4B04A 3ZM0A 4JMJA 4GRYA 1T4JA 5KA3A 1G7FA 2HNQA 1RPMA 1NO6A 3S4OA 2R0BA 1X24A 3QKPA 2H4GA 4GFVA 3F9AA 2F6WA 2QBRA 2F6FA 1YTSA 1G1HA 1OETA 3S3FA 1FPRA 3QCKA 5KABA 3O5XA 1D5RA 4NNDA 1FPZA 2FJMA 1C86A 2I75A 3QCIA 2Q47A 4WU3A 1V3AA 1PH0A 3ZMQA 5KA2A 2C7SA 1XXVA 2CMCA 3QCFA 1EEOA 1WRMA 2HNPA 3QCEA 5BZZA 1C87A 1Q6JA 2FJNA 3V0HA 5KA7A 4RH5A 2CMAA 4NX8A 1G1FA 2CM7A 2I1YA 1PTYA 1PXHA 3MMJA 4GRZA 2B4OA 4Y14A 3ZM1A 5KA9A 2QDMA 3M4UA 4H1OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I4E A;  4QUM A;  4R0S A;  1JF7 A;  2B3O A;  4R30 A;  3BM8 A;  5BUG A;  4GE2 A;  2HXP A;  4BPC A;  2I6J A;  3CM3 A;  5K9W A;  3EZZ A;  1ZCL A;  4WOH A;  1ZZW A;  3D1H A;  3D1O A;  1Q6P A;  2F46 A;  1I9S A;  2VEY A;  1RXD A;  1KAV A;  2Q05 A;  2QDC A;  3A5K A;  2CFV A;  2G6Z A;  5MMZ B;  2IMG A;  5K9V A;  4QBW A;  3S3E A;  5J8R A;  2J16 B;  3EAX A;  2B4S A;  4ERC A;  1YGU A;  5AWX A;  4HRF A;  1XM2 A;  4JBC A;  1YTN A;  1QXK A;  1XXP A;  1C84 A;  3D1Q A;  2J16 A;  2F6Z A;  2I6I A;  5K22 A;  4GS0 A;  3QCJ A;  4D3R A;  5K25 A;  4ZN5 A;  3F99 A;  1U25 A;  2AHS A;  4HJP A;  1QZ0 A;  2A3K A;  4HJQ A;  3SME A;  4KYR A;  3RO1 A;  1MKP A;  2MBC A;  2BV5 A;  2QCT A;  3QCG A;  4TVV A;  4IKC A;  2WGP A;  3V0G A;  4YAA A;  2GJT A;  1PYN A;  2CM2 A;  1OHC A;  1G1G A;  2B4P A;  1Q6S A;  3MOZ A;  5BZX A;  2VEW A;  2I3U A;  1C88 A;  1EEN A;  1NL9 A;  5EHP A;  1YPT A;  2F6V A;  4ICZ A;  4RHG A;  4RH9 A;  4DGP A;  3QCN A;  2I3R A;  1M3G A;  3I80 A;  2JJD A;  2E0T A;  1J4X A;  4Y2E A;  2PSZ A;  2GWO A;  3QCB A;  2P4D A;  4D3P A;  4NWG A;  1L8K A;  3O3L A;  3BLU A;  3S4E A;  2H4V A;  3QCD A;  1OEM X;  5KA0 A;  2CNH A;  1ONZ A;  4NWF A;  2VEU A;  3O4T A;  3RGQ A;  2ZN7 A;  2A8B A;  1I9T A;  5LXQ B;  4KYQ A;  2OUD A;  1YN9 A;  2NT7 A;  5KA8 A;  3QCL A;  5K24 A;  4PYH A;  1PA1 A;  2NV5 A;  3MOW A;  4I8N A;  3V0D A;  2F71 A;  5M43 A;  1BZJ A;  5KA1 A;  2QBQ A;  3OLR A;  2B4U A;  2DXP A;  3NME A;  2I4H A;  2NLK A;  1OEO X;  3EU0 A;  4RI4 A;  1FQ1 A;  5HDE A;  1ZCK A;  4OHL A;  3BRH A;  1Q6M A;  2PBN A;  4JMK A;  2CNF A;  5IBS A;  1VHR A;  2AZR A;  3I7Z A;  4AZ1 A;  1XBO A;  1Q6T A;  2NZ6 A;  2B49 A;  3AWG A;  2QCJ A;  4ZI4 A;  3N0A A;  4QBE A;  3QCH A;  5I6V A;  2OZ5 A;  2BZL A;  2VEX A;  2I5X A;  1PTT A;  1I57 A;  2J17 A;  3GXH A;  2HCM A;  1C85 A;  1YGR A;  3V0E A;  2B07 A;  3PS5 A;  2G59 A;  2M3V A;  2HC2 A;  2Y2F A;  3S3H A;  2F6T A;  1A5Y A;  1L8G A;  1NNY A;  1YWF A;  1OEU A;  3QKQ A;  1OES A;  1ZC0 A;  2QBS A;  1YFO A;  1OHE A;  2OOQ A;  4MBB A;  4OHI A;  4WU2 A;  2PT0 A;  3RGO A;  4RI5 A;  1LQF A;  2F6Y A;  1P15 A;  5BX1 A;  1LYV A;  5GTJ A;  2NT2 A;  1XRI A;  1WCH A;  4GWF A;  4Z6B A;  5EHR A;  3V0F A;  1T48 A;  2C46 A;  4OHH A;  4J51 A;  2CM3 A;  2GP0 A;  1G4W R;  5IBM A;  2YDU A;  1Q6N A;  1G7G A;  3EMU A;  4QUN A;  2FH7 A;  1OHD A;  3D9C A;  1JLN A;  3ZM2 A;  1Q1M A;  1ECV A;  2CNI A;  3AWF A;  2VEV A;  1SUG A;  3I36 A;  2SHP A;  3B7O A;  4GE6 A;  1AAX A;  3O4S A;  2HVL A;  2QEP A;  4H34 A;  4GFU A;  4JNB A;  2OC3 A;  3ZV2 A;  1NZ7 A;  1ONY A;  3ZMP A;  2PA5 A;  3EB1 A;  2CNG A;  2RF6 A;  5KAD A;  2H02 A;  1GWZ A;  3BLT A;  3SR9 A;  3D44 A;  3O4U A;  4GE5 A;  1T49 A;  3S3K A;  1G4U S;  2BIJ A;  4QAP A;  2NTA A;  3V0J A;  5KAC A;  4YR8 B;  5KA4 A;  2QDP A;  3ZM3 A;  1WAX A;  3V0I A;  3RZ2 A;  4D3Q A;  1BZC A;  1NWE A;  3F81 A;  3F9B A;  2I6M A;  4DGX A;  4R0T A;  3OMH A;  1GFY A;  2ESB A;  3A5J A;  1PTU A;  2CM8 A;  4QAH A;  3F41 A;  2H03 A;  3CWE A;  2F70 A;  1BZH A;  2CNE A;  4WTY A;  5KAA A;  4OHD A;  2I6O A;  2CJZ A;  2I4G A;  2P6X A;  2PI7 A;  2I6P A;  2I42 A;  4OHE A;  3QCC A;  1C83 A;  2PQ5 A;  1U24 A;  2QBP A;  4RKK A;  4PVG A;  4NYH A;  1OEV A;  5K23 A;  1U26 A;  2ZMM A;  4KI9 A;  4S0G A;  3QCM A;  2H04 A;  3U96 A;  3GXG A;  3LJ8 A;  1YTW A;  2CMB A;  2BGE A;  2HC1 A;  4BJO A;  2H4K A;  3AWE A;  4ZRT A;  1NWL A;  4RDD A;  2HB1 A;  1LAR A;  2HY3 A;  3H2X A;  3D42 A;  1KAK A;  2Y96 A;  1R6H A;  1YZ4 A;  1PA9 A;  2BGD A;  1PTV A;  4B04 A;  3ZM0 A;  4JMJ A;  4GRY A;  1T4J A;  5KA3 A;  1G7F A;  2HNQ A;  1RPM A;  1NO6 A;  3S4O A;  2R0B A;  1X24 A;  3QKP A;  2H4G A;  4GFV A;  3F9A A;  2F6W A;  2QBR A;  2F6F A;  1YTS A;  1G1H A;  1OET A;  3S3F A;  1FPR A;  3QCK A;  5KAB A;  3O5X A;  1D5R A;  4NND A;  1FPZ A;  2FJM A;  1C86 A;  2I75 A;  3QCI A;  2Q47 A;  4WU3 A;  1V3A A;  1PH0 A;  3ZMQ A;  5KA2 A;  2C7S A;  1XXV A;  2CMC A;  3QCF A;  1EEO A;  1WRM A;  2HNP A;  3QCE A;  5BZZ A;  1C87 A;  1Q6J A;  2FJN A;  3V0H A;  5KA7 A;  4RH5 A;  2CMA A;  4NX8 A;  1G1F A;  2CM7 A;  2I1Y A;  1PTY A;  1PXH A;  3MMJ A;  4GRZ A;  2B4O A;  4Y14 A;  3ZM1 A;  5KA9 A;  2QDM A;  3M4U A;  4H1O A; 
#chains in the Genus database with same CATH topology
 2I4E A;  4QUM A;  4R0S A;  5A5F A;  1JF7 A;  2JFG A;  2B3O A;  4R30 A;  3BM8 A;  5BUG A;  4GE2 A;  2HXP A;  4BPC A;  2I6J A;  3CM3 A;  5K9W A;  3EZZ A;  1ZCL A;  4WOH A;  1ZZW A;  3D1H A;  3D1O A;  1Q6P A;  2F46 A;  1I9S A;  2VEY A;  2UUP A;  3A5K A;  1RXD A;  1KAV A;  2Q05 A;  2QDC A;  1E8C A;  2CFV A;  2G6Z A;  5MMZ B;  2IMG A;  5K9V A;  2JFF A;  4QBW A;  1GQY A;  3S3E A;  2Y67 A;  5J8R A;  2J16 B;  3EAX A;  2B4S A;  4ERC A;  1YGU A;  5AWX A;  4HRF A;  1XM2 A;  4JBC A;  1YTN A;  1QXK A;  1XXP A;  1C84 A;  3D1Q A;  2J16 A;  2F6Z A;  2I6I A;  5K22 A;  4GS0 A;  3QCJ A;  4D3R A;  5K25 A;  4ZN5 A;  3F99 A;  1U25 A;  2AHS A;  4HJP A;  1QZ0 A;  2A3K A;  3UAG A;  4HJQ A;  3SME A;  4KYR A;  3RO1 A;  1MKP A;  2MBC A;  2BV5 A;  2QCT A;  2X5O A;  3QCG A;  4TVV A;  4IKC A;  2WGP A;  3V0G A;  4YAA A;  2GJT A;  1PYN A;  2CM2 A;  1OHC A;  1G1G A;  2B4P A;  1Q6S A;  3MOZ A;  5BZX A;  2VEW A;  2I3U A;  1C88 A;  1EEN A;  1NL9 A;  5EHP A;  2WJP A;  1YPT A;  2F6V A;  4ICZ A;  4RHG A;  4RH9 A;  4DGP A;  3QCN A;  2I3R A;  1M3G A;  3I80 A;  2GCA A;  2VTD A;  2JJD A;  2Y1O A;  2E0T A;  1J4X A;  4Y2E A;  2Y66 A;  2PSZ A;  2GWO A;  3QCB A;  2P4D A;  4D3P A;  1O5Z A;  4NWG A;  1L8K A;  3O3L A;  2XPC A;  3BLU A;  3S4E A;  2H4V A;  3QCD A;  1OEM X;  5KA0 A;  2CNH A;  1ONZ A;  4NWF A;  2VEU A;  3O4T A;  3RGQ A;  2ZN7 A;  3ZM5 A;  2A8B A;  1J6U A;  1I9T A;  5LXQ B;  3HN7 A;  4KYQ A;  2OUD A;  1YN9 A;  2NT7 A;  5KA8 A;  3QCL A;  5K24 A;  4PYH A;  1PA1 A;  2NV5 A;  3MOW A;  4I8N A;  3V0D A;  2F71 A;  5M43 A;  1BZJ A;  5KA1 A;  2QBQ A;  3OLR A;  2B4U A;  2DXP A;  3NME A;  2I4H A;  1JBV A;  2NLK A;  1OEO X;  3EU0 A;  4RI4 A;  1FQ1 A;  5HDE A;  1ZCK A;  4OHL A;  2Y68 A;  2GC6 A;  3BRH A;  1Q6M A;  2PBN A;  4JMK A;  2CNF A;  5IBS A;  1VHR A;  2AZR A;  3I7Z A;  4AZ1 A;  1XBO A;  1Q6T A;  2NZ6 A;  2B49 A;  3AWG A;  2QCJ A;  4ZI4 A;  2F00 A;  4HV4 A;  2VTE A;  3N0A A;  4QBE A;  3QCH A;  5I6V A;  2OZ5 A;  2BZL A;  2VEX A;  2I5X A;  1PTT A;  1I57 A;  2J17 A;  3GXH A;  2HCM A;  1C85 A;  1YGR A;  4CVM A;  3V0E A;  2B07 A;  3PS5 A;  2GCB A;  2G59 A;  2M3V A;  2HC2 A;  4BUC A;  2Y2F A;  3S3H A;  2F6T A;  1A5Y A;  1L8G A;  1NNY A;  1YWF A;  2AM1 A;  1OEU A;  3QKQ A;  1OES A;  1ZC0 A;  2QBS A;  1YFO A;  1OHE A;  2OOQ A;  4MBB A;  4OHI A;  4WU2 A;  2PT0 A;  3RGO A;  4BUB A;  4RI5 A;  1LQF A;  2F6Y A;  1P15 A;  5BX1 A;  1LYV A;  5GTJ A;  4CVK A;  2NT2 A;  1XRI A;  1WCH A;  4GWF A;  4Z6B A;  5EHR A;  2AM2 A;  3V0F A;  1T48 A;  2C46 A;  4OHH A;  4J51 A;  2CM3 A;  2GP0 A;  1G4W R;  5IBM A;  3N2A A;  2YDU A;  1Q6N A;  1G7G A;  3EMU A;  4CVL A;  4QUN A;  2FH7 A;  4C13 A;  1OHD A;  1UAG A;  3D9C A;  1JLN A;  3ZM2 A;  1Q1M A;  1ECV A;  2CNI A;  3AWF A;  2UAG A;  1GQQ A;  2VEV A;  1SUG A;  1P31 A;  3I36 A;  2SHP A;  3B7O A;  4GE6 A;  1AAX A;  3O4S A;  2HVL A;  2QEP A;  2XJA A;  3PYZ A;  4H34 A;  1W78 A;  4GFU A;  2OC3 A;  4JNB A;  1P3D A;  3ZV2 A;  1NZ7 A;  1ONY A;  5A5E A;  3ZMP A;  2VOR A;  2PA5 A;  3EB1 A;  2CNG A;  2RF6 A;  4QF5 A;  5KAD A;  2H02 A;  2UUO A;  1FGS A;  3BLT A;  1GWZ A;  2WTZ A;  3SR9 A;  3D44 A;  3O4U A;  4GE5 A;  1T49 A;  3S3K A;  1G4U S;  2BIJ A;  4QAP A;  4UAG A;  2NTA A;  3V0J A;  5KAC A;  4YR8 B;  1W7K A;  2QDP A;  5KA4 A;  3ZM3 A;  1WAX A;  3V0I A;  3RZ2 A;  4D3Q A;  1BZC A;  1NWE A;  3F81 A;  3F9B A;  2I6M A;  2GC5 A;  4DGX A;  4C12 A;  4R0T A;  3OMH A;  1GFY A;  2ESB A;  3A5J A;  1PTU A;  2CM8 A;  4QAH A;  3F41 A;  2H03 A;  3NRS A;  3CWE A;  2F70 A;  1BZH A;  2CNE A;  4WTY A;  5KAA A;  4OHD A;  2I6O A;  2CJZ A;  2I4G A;  2P6X A;  2PI7 A;  2I42 A;  2I6P A;  4OHE A;  3QCC A;  1C83 A;  2PQ5 A;  1U24 A;  3ZM6 A;  2QBP A;  4RKK A;  4PVG A;  4NYH A;  1OEV A;  5K23 A;  1U26 A;  2ZMM A;  4KI9 A;  4S0G A;  3QCM A;  3MVN A;  2H04 A;  3U96 A;  3GXG A;  3LK7 A;  3LJ8 A;  1JBW A;  1YTW A;  2CMB A;  2BGE A;  2HC1 A;  4BJO A;  2H4K A;  3AWE A;  4ZRT A;  1NWL A;  4RDD A;  2HB1 A;  1LAR A;  2JFH A;  2HY3 A;  3H2X A;  3D42 A;  1KAK A;  2Y96 A;  1R6H A;  1YZ4 A;  1PA9 A;  2BGD A;  1PTV A;  4B04 A;  3ZM0 A;  4JMJ A;  4GRY A;  4QDI A;  3ZL8 A;  1T4J A;  5KA3 A;  1G7F A;  2HNQ A;  1RPM A;  1NO6 A;  3S4O A;  2R0B A;  1X24 A;  3QKP A;  2H4G A;  4GFV A;  3F9A A;  2F6W A;  2QBR A;  2F6F A;  1YTS A;  1G1H A;  1OET A;  3S3F A;  1FPR A;  3QCK A;  5KAB A;  3O5X A;  1D5R A;  2VOS A;  4NND A;  1E0D A;  1FPZ A;  2FJM A;  1C86 A;  2I75 A;  3QCI A;  2Q47 A;  4WU3 A;  1V3A A;  1PH0 A;  3ZMQ A;  5KA2 A;  3QCZ A;  2C7S A;  1XXV A;  2CMC A;  3QCF A;  1EEO A;  1WRM A;  2HNP A;  3QCE A;  1GG4 A;  5BZZ A;  1C87 A;  1Q6J A;  1EEH A;  2FJN A;  4ZIY A;  3V0H A;  5KA7 A;  4RH5 A;  2CMA A;  4NX8 A;  1G1F A;  2CM7 A;  2I1Y A;  1PTY A;  1PXH A;  3MMJ A;  4GRZ A;  2B4O A;  4Y14 A;  3ZM1 A;  5KA9 A;  2QDM A;  3M4U A;  4H1O A; 
#chains in the Genus database with same CATH homology
 2I4E A;  4QUM A;  4R0S A;  1JF7 A;  2B3O A;  4R30 A;  3BM8 A;  5BUG A;  4GE2 A;  2HXP A;  4BPC A;  2I6J A;  3CM3 A;  5K9W A;  3EZZ A;  1ZCL A;  4WOH A;  1ZZW A;  3D1H A;  3D1O A;  1Q6P A;  2F46 A;  1I9S A;  2VEY A;  1RXD A;  1KAV A;  2Q05 A;  2QDC A;  3A5K A;  2CFV A;  2G6Z A;  5MMZ B;  2IMG A;  5K9V A;  4QBW A;  3S3E A;  5J8R A;  2J16 B;  3EAX A;  2B4S A;  4ERC A;  1YGU A;  5AWX A;  4HRF A;  1XM2 A;  4JBC A;  1YTN A;  1QXK A;  1XXP A;  1C84 A;  3D1Q A;  2J16 A;  2F6Z A;  2I6I A;  5K22 A;  4GS0 A;  3QCJ A;  4D3R A;  5K25 A;  4ZN5 A;  3F99 A;  1U25 A;  2AHS A;  4HJP A;  1QZ0 A;  2A3K A;  4HJQ A;  3SME A;  4KYR A;  3RO1 A;  1MKP A;  2MBC A;  2BV5 A;  2QCT A;  3QCG A;  4TVV A;  4IKC A;  2WGP A;  3V0G A;  4YAA A;  2GJT A;  1PYN A;  2CM2 A;  1OHC A;  1G1G A;  2B4P A;  1Q6S A;  3MOZ A;  5BZX A;  2VEW A;  2I3U A;  1C88 A;  1EEN A;  1NL9 A;  5EHP A;  1YPT A;  2F6V A;  4ICZ A;  4RHG A;  4RH9 A;  4DGP A;  3QCN A;  2I3R A;  1M3G A;  3I80 A;  2JJD A;  2E0T A;  1J4X A;  4Y2E A;  2PSZ A;  2GWO A;  3QCB A;  2P4D A;  4D3P A;  4NWG A;  1L8K A;  3O3L A;  3BLU A;  3S4E A;  2H4V A;  3QCD A;  1OEM X;  5KA0 A;  2CNH A;  1ONZ A;  4NWF A;  2VEU A;  3O4T A;  3RGQ A;  2ZN7 A;  2A8B A;  1I9T A;  5LXQ B;  4KYQ A;  2OUD A;  1YN9 A;  2NT7 A;  5KA8 A;  3QCL A;  5K24 A;  4PYH A;  1PA1 A;  2NV5 A;  3MOW A;  4I8N A;  3V0D A;  2F71 A;  5M43 A;  1BZJ A;  5KA1 A;  2QBQ A;  3OLR A;  2B4U A;  2DXP A;  3NME A;  2I4H A;  2NLK A;  1OEO X;  3EU0 A;  4RI4 A;  1FQ1 A;  5HDE A;  1ZCK A;  4OHL A;  3BRH A;  1Q6M A;  2PBN A;  4JMK A;  2CNF A;  5IBS A;  1VHR A;  2AZR A;  3I7Z A;  4AZ1 A;  1XBO A;  1Q6T A;  2NZ6 A;  2B49 A;  3AWG A;  2QCJ A;  4ZI4 A;  3N0A A;  4QBE A;  3QCH A;  5I6V A;  2OZ5 A;  2BZL A;  2VEX A;  2I5X A;  1PTT A;  1I57 A;  2J17 A;  3GXH A;  2HCM A;  1C85 A;  1YGR A;  3V0E A;  2B07 A;  3PS5 A;  2G59 A;  2M3V A;  2HC2 A;  2Y2F A;  3S3H A;  2F6T A;  1A5Y A;  1L8G A;  1NNY A;  1YWF A;  1OEU A;  3QKQ A;  1OES A;  1ZC0 A;  2QBS A;  1YFO A;  1OHE A;  2OOQ A;  4MBB A;  4OHI A;  4WU2 A;  2PT0 A;  3RGO A;  4RI5 A;  1LQF A;  2F6Y A;  1P15 A;  5BX1 A;  1LYV A;  5GTJ A;  2NT2 A;  1XRI A;  1WCH A;  4GWF A;  4Z6B A;  5EHR A;  3V0F A;  1T48 A;  2C46 A;  4OHH A;  4J51 A;  2CM3 A;  2GP0 A;  1G4W R;  5IBM A;  2YDU A;  1Q6N A;  1G7G A;  3EMU A;  4QUN A;  2FH7 A;  1OHD A;  3D9C A;  1JLN A;  3ZM2 A;  1Q1M A;  1ECV A;  2CNI A;  3AWF A;  2VEV A;  1SUG A;  3I36 A;  2SHP A;  3B7O A;  4GE6 A;  1AAX A;  3O4S A;  2HVL A;  2QEP A;  4H34 A;  4GFU A;  4JNB A;  2OC3 A;  3ZV2 A;  1NZ7 A;  1ONY A;  3ZMP A;  2PA5 A;  3EB1 A;  2CNG A;  2RF6 A;  5KAD A;  2H02 A;  1GWZ A;  3BLT A;  3SR9 A;  3D44 A;  3O4U A;  4GE5 A;  1T49 A;  3S3K A;  1G4U S;  2BIJ A;  4QAP A;  2NTA A;  3V0J A;  5KAC A;  4YR8 B;  5KA4 A;  2QDP A;  3ZM3 A;  1WAX A;  3V0I A;  3RZ2 A;  4D3Q A;  1BZC A;  1NWE A;  3F81 A;  3F9B A;  2I6M A;  4DGX A;  4R0T A;  3OMH A;  1GFY A;  2ESB A;  3A5J A;  1PTU A;  2CM8 A;  4QAH A;  3F41 A;  2H03 A;  3CWE A;  2F70 A;  1BZH A;  2CNE A;  4WTY A;  5KAA A;  4OHD A;  2I6O A;  2CJZ A;  2I4G A;  2P6X A;  2PI7 A;  2I6P A;  2I42 A;  4OHE A;  3QCC A;  1C83 A;  2PQ5 A;  1U24 A;  2QBP A;  4RKK A;  4PVG A;  4NYH A;  1OEV A;  5K23 A;  1U26 A;  2ZMM A;  4KI9 A;  4S0G A;  3QCM A;  2H04 A;  3U96 A;  3GXG A;  3LJ8 A;  1YTW A;  2CMB A;  2BGE A;  2HC1 A;  4BJO A;  2H4K A;  3AWE A;  4ZRT A;  1NWL A;  4RDD A;  2HB1 A;  1LAR A;  2HY3 A;  3H2X A;  3D42 A;  1KAK A;  2Y96 A;  1R6H A;  1YZ4 A;  1PA9 A;  2BGD A;  1PTV A;  4B04 A;  3ZM0 A;  4JMJ A;  4GRY A;  1T4J A;  5KA3 A;  1G7F A;  2HNQ A;  1RPM A;  1NO6 A;  3S4O A;  2R0B A;  1X24 A;  3QKP A;  2H4G A;  4GFV A;  3F9A A;  2F6W A;  2QBR A;  2F6F A;  1YTS A;  1G1H A;  1OET A;  3S3F A;  1FPR A;  3QCK A;  5KAB A;  3O5X A;  1D5R A;  4NND A;  1FPZ A;  2FJM A;  1C86 A;  2I75 A;  3QCI A;  2Q47 A;  4WU3 A;  1V3A A;  1PH0 A;  3ZMQ A;  5KA2 A;  2C7S A;  1XXV A;  2CMC A;  3QCF A;  1EEO A;  1WRM A;  2HNP A;  3QCE A;  5BZZ A;  1C87 A;  1Q6J A;  2FJN A;  3V0H A;  5KA7 A;  4RH5 A;  2CMA A;  4NX8 A;  1G1F A;  2CM7 A;  2I1Y A;  1PTY A;  1PXH A;  3MMJ A;  4GRZ A;  2B4O A;  4Y14 A;  3ZM1 A;  5KA9 A;  2QDM A;  3M4U A;  4H1O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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