1I57A

Crystal structure of apo human ptp1b (c215s) mutant
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
284
structure length
284
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHSSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of apo protein-tyrosine phosphatase 1B C215S mutant: more than just an S --> O change.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PHOSPHO-TYROSINE PHOSPHATASE 1B
total genus 97
structure length 284
sequence length 284
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2001-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1i57A00
4PVGA 2I6JA 4NWFA 2SHPA 4Y14A 2IMGA 2CNFA 1GWZA 2AHSA 3N0AA 3CWEA 3O4TA 1AAXA 1NWEA 2CMAA 3D9CA 3F41A 2Y2FA 4D3QA 2CM8A 3O4SA 3H2XA 4YAAA 2GP0A 1PA1A 5KA3A 2ZMMA 1YGUA 4OHLA 2G6ZA 3QCLA 2CM3A 1NNYA 4QAHA 4NWGA 1YTNA 2FJNA 2Q05A 1G7FA 2GWOA 4IKCA 3RZ2A 3I80A 5BUGA 2OC3A 2HCMA 2R0BA 1EEOA 4QAPA 4RKKA 5EHPA 2QDPA 1KAKA 2HC1A 5KA0A 1PTVA 2AZRA 2QBPA 4WOHA 3QCFA 1LARA 2CFVA 1ZC0A 2ZN7A 3PS5A 1OHCA 3D1OA 3QCIA 2ESBA 4BJOA 1OHDA 2I1YA 1Q6NA 1Q6TA 2B4UA 3QCCA 3D1HA 5K23A 4J51A 1OEUA 4WU2A 2NTAA 1XM2A 4GE2A 4AZ1A 3ZMPA 2A3KA 3MMJA 2HB1A 2CMBA 2H02A 1C88A 3O4UA 1I57A 2CNGA 4ZI4A 3F81A 1C87A 1FPZA 1A5YA 2BZLA 3I36A 3QCJA 1PYNA 1G4US 5KA1A 2VEUA 1YTSA 2I4HA 5AWXA 3AWGA 2B4SA 3ZMQA 2Y96A 5J8RA 2F6YA 4RHGA 2PA5A 4WTYA 3D42A 4HRFA 4GRYA 2HNQA 3QKQA 1ZZWA 4JBCA 3AWFA 1NWLA 2CNIA 2CNEA 2DXPA 1T49A 2QEPA 3EAXA 4I8NA 1C84A 5I6VA 1VHRA 2FH7A 1Q6MA 2I4EA 3S4EA 2A8BA 4H34A 4RH5A 1GFYA 1OESA 3BLTA 2I6OA 2CNHA 5K24A 5K25A 5K9VA 2J17A 5KA9A 4TVVA 5KA4A 5KACA 1JLNA 4NNDA 2HXPA 5MMZB 2HY3A 2MBCA 1YN9A 3ZM0A 2NLKA 4ERCA 1J4XA 2B4PA 3QCDA 4RI4A 3O3LA 3F9AA 5IBSA 1P15A 2I6PA 2QBQA 1WRMA 2QBSA 1V3AA 4NX8A 4D3RA 2HNPA 1C86A 2F70A 1XXVA 3BM8A 1NZ7A 2H04A 4KYRA 1PA9A 2F6TA 3NMEA 2Q47A 2PT0A 3QCHA 2F6FA 1C83A 4JMKA 2P6XA 1BZJA 2VEWA 2HC2A 3EMUA 2OOQA 4D3PA 2JJDA 3OMHA 3U96A 1NL9A 1FQ1A 4H1OA 2G59A 1G4WR 3OLRA 1LYVA 2H4VA 2VEXA 1EENA 2B3OA 2BGDA 1RPMA 4OHEA 1ONYA 1ZCKA 1L8KA 2CMCA 4PYHA 2F71A 4NYHA 3QCBA 3BLUA 1PH0A 2QCJA 1PXHA 3S4OA 1XBOA 1YGRA 1OHEA 2I75A 1U24A 2PI7A 4QUMA 3V0HA 5HDEA 1XRIA 5GTJA 1M3GA 1OEMX 1MKPA 1LQFA 2GJTA 1R6HA 1BZCA 2HVLA 4BPCA 1T48A 3RO1A 2E0TA 1OETA 4JMJA 3V0JA 5BZZA 1Q6SA 1U26A 1WCHA 4QUNA 2CJZA 4DGPA 5BZXA 4Z6BA 1G1GA 3ZM1A 1I9TA 2F6WA 3S3KA 2I4GA 1YZ4A 1G1HA 1QXKA 4GE6A 5M43A 2P4DA 4RDDA 4RH9A 3RGQA 2M3VA 4HJPA 3F99A 3QKPA 2H4KA 2PQ5A 5IBMA 5KAAA 3BRHA 1KAVA 5K9WA 1BZHA 2CM7A 2NV5A 1YPTA 4R30A 3V0EA 2B07A 1G1FA 2J16B 3QCEA 4YR8B 1ZCLA 2I5XA 3V0IA 1YWFA 5KABA 1X24A 1ONZA 4ZN5A 4HJQA 3V0GA 2FJMA 2I3RA 2BGEA 5KA7A 5LXQB 1OEVA 4WU3A 3EZZA 4S0GA 2NT7A 3S3EA 2I6MA 4QBEA 1PTUA 1L8GA 4DGXA 1PTTA 1SUGA 1Q1MA 2NT2A 2RF6A 3S3FA 1FPRA 4GS0A 1U25A 2OUDA 2I6IA 2I3UA 1NO6A 4GFVA 3LJ8A 4Y2EA 3RGOA 5BX1A 2I42A 2QBRA 4OHHA 4ZRTA 2NZ6A 3QCNA 4MBBA 2B4OA 1YTWA 3A5JA 2PBNA 4OHIA 1G7GA 2BV5A 3ZM2A 2VEVA 3EU0A 2YDUA 1ECVA 2WGPA 2QCTA 4R0TA 3CM3A 4GFUA 1JF7A 2BIJA 4RI5A 3ZM3A 2J16A 1D5RA 5EHRA 4R0SA 3V0DA 1PTYA 4ICZA 4OHDA 2F6ZA 2CM2A 3I7ZA 3O5XA 3QCKA 4JNBA 1RXDA 3AWEA 1OEOX 4KI9A 5K22A 1YFOA 2QDCA 2VEYA 3V0FA 1QZ0A 1C85A 1WAXA 4QBWA 1Q6JA 3F9BA 3QCGA 4KYQA 4B04A 3GXHA 3SMEA 2H4GA 3M4UA 3S3HA 3A5KA 3ZV2A 3B7OA 3MOZA 5KA8A 4GWFA 2B49A 5KADA 3D1QA 2C7SA 3EB1A 2QDMA 2F46A 3D44A 1Q6PA 1T4JA 3MOWA 2OZ5A 4GRZA 3SR9A 3GXGA 5KA2A 3QCMA 2F6VA 2C46A 1I9SA 2H03A 2PSZA 4GE5A 1XXPA
chains in the Genus database with same CATH superfamily
4PVGA 2I6JA 4NWFA 1E0DA 2SHPA 4Y14A 2IMGA 2CNFA 1GQYA 1GWZA 2AHSA 3N0AA 3CWEA 3O4TA 1AAXA 1NWEA 2CMAA 3D9CA 3F41A 2Y2FA 4D3QA 4BUCA 3N2AA 2CM8A 3O4SA 3H2XA 4YAAA 2GP0A 1PA1A 5KA3A 1W78A 2ZMMA 1YGUA 2GCAA 4OHLA 2JFFA 2G6ZA 3HN7A 3QCLA 2CM3A 1NNYA 4QAHA 4NWGA 1YTNA 2FJNA 2Q05A 1G7FA 2AM2A 2GWOA 4IKCA 3RZ2A 3I80A 5BUGA 2OC3A 2HCMA 2R0BA 1EEOA 4QAPA 4RKKA 5EHPA 2QDPA 1KAKA 2HC1A 5KA0A 1PTVA 2AZRA 2QBPA 4WOHA 3QCFA 4CVLA 1LARA 2CFVA 1ZC0A 2F00A 2ZN7A 3PS5A 1OHCA 3D1OA 3QCIA 2ESBA 4BJOA 1OHDA 2I1YA 1GG4A 1Q6NA 1Q6TA 2B4UA 3QCCA 3D1HA 5K23A 4J51A 1OEUA 4WU2A 2NTAA 1XM2A 4GE2A 4AZ1A 3ZMPA 2A3KA 2WJPA 3MMJA 2HB1A 2CMBA 2H02A 1C88A 3O4UA 1I57A 2CNGA 4ZI4A 3F81A 1C87A 4ZIYA 1FPZA 1A5YA 2BZLA 3I36A 3QCJA 1PYNA 2XPCA 1G4US 3ZM5A 1W7KA 5KA1A 2VEUA 1YTSA 2I4HA 5AWXA 3AWGA 3NRSA 2B4SA 2GC6A 3ZMQA 2Y96A 5J8RA 2F6YA 4RHGA 2PA5A 4HV4A 4WTYA 3D42A 4HRFA 4GRYA 2HNQA 3QKQA 1ZZWA 4JBCA 3AWFA 1NWLA 2CNIA 2AM1A 2CNEA 2DXPA 1T49A 2VTDA 2QEPA 4CVMA 3EAXA 4I8NA 1C84A 5I6VA 1VHRA 2FH7A 1Q6MA 2I4EA 3S4EA 2A8BA 4H34A 4RH5A 1GFYA 1OESA 3BLTA 2I6OA 2CNHA 5K24A 5K25A 5K9VA 2J17A 5KA9A 4TVVA 5KA4A 5KACA 1JLNA 4NNDA 2HXPA 5MMZB 2HY3A 2MBCA 1YN9A 3ZM0A 2NLKA 4ERCA 1J4XA 2B4PA 3QCDA 4RI4A 3O3LA 3F9AA 5IBSA 1P15A 2I6PA 2QBQA 1WRMA 2QBSA 1V3AA 4NX8A 4D3RA 2HNPA 1C86A 2F70A 1XXVA 3BM8A 1NZ7A 1J6UA 2H04A 4KYRA 1PA9A 2F6TA 3NMEA 3ZL8A 1O5ZA 2UUPA 2Q47A 2PT0A 3QCHA 2F6FA 3MVNA 1C83A 4JMKA 2P6XA 1BZJA 2WTZA 2VEWA 2HC2A 3EMUA 2OOQA 4D3PA 2JJDA 2VORA 2GC5A 3OMHA 3U96A 1UAGA 1NL9A 1FQ1A 4H1OA 2G59A 1G4WR 3OLRA 4UAGA 1LYVA 2H4VA 2JFHA 2VEXA 1EENA 2B3OA 2BGDA 1RPMA 4OHEA 1ONYA 1ZCKA 1L8KA 2CMCA 4PYHA 2F71A 4NYHA 3QCBA 3BLUA 1PH0A 2QCJA 2UUOA 1PXHA 3S4OA 1XBOA 5A5FA 1YGRA 1OHEA 2I75A 1U24A 2PI7A 4QUMA 3V0HA 5HDEA 2JFGA 1XRIA 5GTJA 1M3GA 1OEMX 1MKPA 1LQFA 2GJTA 1R6HA 1JBWA 1BZCA 2HVLA 4BPCA 2Y67A 1FGSA 1T48A 3RO1A 2E0TA 1OETA 4JMJA 3V0JA 5BZZA 1Q6SA 1U26A 2GCBA 1WCHA 4QUNA 2CJZA 4DGPA 5BZXA 4Z6BA 1G1GA 3ZM1A 1I9TA 2F6WA 2Y66A 3S3KA 2I4GA 1YZ4A 1G1HA 1QXKA 4C13A 4GE6A 5M43A 2P4DA 4RDDA 4RH9A 3RGQA 3QCZA 3PYZA 2M3VA 4HJPA 3F99A 3QKPA 2H4KA 2PQ5A 5IBMA 5KAAA 3BRHA 1KAVA 5K9WA 1BZHA 2CM7A 2NV5A 1YPTA 2VTEA 4R30A 3V0EA 2B07A 1G1FA 2J16B 3QCEA 4YR8B 1GQQA 1ZCLA 2I5XA 3V0IA 3UAGA 1YWFA 5KABA 1X24A 1ONZA 4ZN5A 4HJQA 3V0GA 2FJMA 2I3RA 2BGEA 5KA7A 5LXQB 1OEVA 4WU3A 3EZZA 4S0GA 2NT7A 3S3EA 5A5EA 2I6MA 4QBEA 1PTUA 1L8GA 4DGXA 1PTTA 1SUGA 1Q1MA 2NT2A 2RF6A 3S3FA 1FPRA 4GS0A 1U25A 2OUDA 2I6IA 2I3UA 1NO6A 1EEHA 4GFVA 3LJ8A 4Y2EA 3RGOA 5BX1A 1JBVA 2I42A 2QBRA 2X5OA 4CVKA 4OHHA 4ZRTA 2NZ6A 3QCNA 4MBBA 2B4OA 1YTWA 3A5JA 2PBNA 4OHIA 1G7GA 2BV5A 3ZM2A 2VEVA 3EU0A 3ZM6A 2YDUA 1ECVA 2WGPA 4BUBA 2UAGA 2QCTA 4R0TA 3CM3A 4GFUA 1JF7A 2BIJA 2XJAA 4RI5A 3ZM3A 2J16A 1D5RA 5EHRA 4R0SA 3V0DA 2VOSA 1P31A 1PTYA 4ICZA 4OHDA 2F6ZA 2CM2A 3I7ZA 3O5XA 3QCKA 4QF5A 4JNBA 1RXDA 3AWEA 1OEOX 4KI9A 5K22A 2Y68A 1YFOA 2QDCA 2VEYA 3V0FA 1QZ0A 1C85A 1WAXA 3LK7A 4QBWA 1Q6JA 3F9BA 3QCGA 4KYQA 4B04A 3GXHA 3SMEA 2H4GA 3M4UA 3S3HA 3A5KA 3ZV2A 3B7OA 3MOZA 2Y1OA 5KA8A 4QDIA 4GWFA 2B49A 5KADA 3D1QA 2C7SA 3EB1A 2QDMA 2F46A 3D44A 1E8CA 1Q6PA 1T4JA 3MOWA 2OZ5A 4GRZA 3SR9A 3GXGA 5KA2A 3QCMA 4C12A 2F6VA 1P3DA 2C46A 1I9SA 2H03A 2PSZA 4GE5A 1XXPA
chains in the Genus database with same CATH topology
4PVGA 2I6JA 4NWFA 2SHPA 4Y14A 2IMGA 2CNFA 1GWZA 2AHSA 3N0AA 3CWEA 3O4TA 1AAXA 1NWEA 2CMAA 3D9CA 3F41A 2Y2FA 4D3QA 2CM8A 3O4SA 3H2XA 4YAAA 2GP0A 1PA1A 5KA3A 2ZMMA 1YGUA 4OHLA 2G6ZA 3QCLA 2CM3A 1NNYA 4QAHA 4NWGA 1YTNA 2FJNA 2Q05A 1G7FA 2GWOA 4IKCA 3RZ2A 3I80A 5BUGA 2OC3A 2HCMA 2R0BA 1EEOA 4QAPA 4RKKA 5EHPA 2QDPA 1KAKA 2HC1A 5KA0A 1PTVA 2AZRA 2QBPA 4WOHA 3QCFA 1LARA 2CFVA 1ZC0A 2ZN7A 3PS5A 1OHCA 3D1OA 3QCIA 2ESBA 4BJOA 1OHDA 2I1YA 1Q6NA 1Q6TA 2B4UA 3QCCA 3D1HA 5K23A 4J51A 1OEUA 4WU2A 2NTAA 1XM2A 4GE2A 4AZ1A 3ZMPA 2A3KA 3MMJA 2HB1A 2CMBA 2H02A 1C88A 3O4UA 1I57A 2CNGA 4ZI4A 3F81A 1C87A 1FPZA 1A5YA 2BZLA 3I36A 3QCJA 1PYNA 1G4US 5KA1A 2VEUA 1YTSA 2I4HA 5AWXA 3AWGA 2B4SA 3ZMQA 2Y96A 5J8RA 2F6YA 4RHGA 2PA5A 4WTYA 3D42A 4HRFA 4GRYA 2HNQA 3QKQA 1ZZWA 4JBCA 3AWFA 1NWLA 2CNIA 2CNEA 2DXPA 1T49A 2QEPA 3EAXA 4I8NA 1C84A 5I6VA 1VHRA 2FH7A 1Q6MA 2I4EA 3S4EA 2A8BA 4H34A 4RH5A 1GFYA 1OESA 3BLTA 2I6OA 2CNHA 5K24A 5K25A 5K9VA 2J17A 5KA9A 4TVVA 5KA4A 5KACA 1JLNA 4NNDA 2HXPA 5MMZB 2HY3A 2MBCA 1YN9A 3ZM0A 2NLKA 4ERCA 1J4XA 2B4PA 3QCDA 4RI4A 3O3LA 3F9AA 5IBSA 1P15A 2I6PA 2QBQA 1WRMA 2QBSA 1V3AA 4NX8A 4D3RA 2HNPA 1C86A 2F70A 1XXVA 3BM8A 1NZ7A 2H04A 4KYRA 1PA9A 2F6TA 3NMEA 2Q47A 2PT0A 3QCHA 2F6FA 1C83A 4JMKA 2P6XA 1BZJA 2VEWA 2HC2A 3EMUA 2OOQA 4D3PA 2JJDA 3OMHA 3U96A 1NL9A 1FQ1A 4H1OA 2G59A 1G4WR 3OLRA 1LYVA 2H4VA 2VEXA 1EENA 2B3OA 2BGDA 1RPMA 4OHEA 1ONYA 1ZCKA 1L8KA 2CMCA 4PYHA 2F71A 4NYHA 3QCBA 3BLUA 1PH0A 2QCJA 1PXHA 3S4OA 1XBOA 1YGRA 1OHEA 2I75A 1U24A 2PI7A 4QUMA 3V0HA 5HDEA 1XRIA 5GTJA 1M3GA 1OEMX 1MKPA 1LQFA 2GJTA 1R6HA 1BZCA 2HVLA 4BPCA 1T48A 3RO1A 2E0TA 1OETA 4JMJA 3V0JA 5BZZA 1Q6SA 1U26A 1WCHA 4QUNA 2CJZA 4DGPA 5BZXA 4Z6BA 1G1GA 3ZM1A 1I9TA 2F6WA 3S3KA 2I4GA 1YZ4A 1G1HA 1QXKA 4GE6A 5M43A 2P4DA 4RDDA 4RH9A 3RGQA 2M3VA 4HJPA 3F99A 3QKPA 2H4KA 2PQ5A 5IBMA 5KAAA 3BRHA 1KAVA 5K9WA 1BZHA 2CM7A 2NV5A 1YPTA 4R30A 3V0EA 2B07A 1G1FA 2J16B 3QCEA 4YR8B 1ZCLA 2I5XA 3V0IA 1YWFA 5KABA 1X24A 1ONZA 4ZN5A 4HJQA 3V0GA 2FJMA 2I3RA 2BGEA 5KA7A 5LXQB 1OEVA 4WU3A 3EZZA 4S0GA 2NT7A 3S3EA 2I6MA 4QBEA 1PTUA 1L8GA 4DGXA 1PTTA 1SUGA 1Q1MA 2NT2A 2RF6A 3S3FA 1FPRA 4GS0A 1U25A 2OUDA 2I6IA 2I3UA 1NO6A 4GFVA 3LJ8A 4Y2EA 3RGOA 5BX1A 2I42A 2QBRA 4OHHA 4ZRTA 2NZ6A 3QCNA 4MBBA 2B4OA 1YTWA 3A5JA 2PBNA 4OHIA 1G7GA 2BV5A 3ZM2A 2VEVA 3EU0A 2YDUA 1ECVA 2WGPA 2QCTA 4R0TA 3CM3A 4GFUA 1JF7A 2BIJA 4RI5A 3ZM3A 2J16A 1D5RA 5EHRA 4R0SA 3V0DA 1PTYA 4ICZA 4OHDA 2F6ZA 2CM2A 3I7ZA 3O5XA 3QCKA 4JNBA 1RXDA 3AWEA 1OEOX 4KI9A 5K22A 1YFOA 2QDCA 2VEYA 3V0FA 1QZ0A 1C85A 1WAXA 4QBWA 1Q6JA 3F9BA 3QCGA 4KYQA 4B04A 3GXHA 3SMEA 2H4GA 3M4UA 3S3HA 3A5KA 3ZV2A 3B7OA 3MOZA 5KA8A 4GWFA 2B49A 5KADA 3D1QA 2C7SA 3EB1A 2QDMA 2F46A 3D44A 1Q6PA 1T4JA 3MOWA 2OZ5A 4GRZA 3SR9A 3GXGA 5KA2A 3QCMA 2F6VA 2C46A 1I9SA 2H03A 2PSZA 4GE5A 1XXPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PVG A;  2I6J A;  4NWF A;  2SHP A;  4Y14 A;  2IMG A;  2CNF A;  1GWZ A;  2AHS A;  3N0A A;  3CWE A;  3O4T A;  1AAX A;  1NWE A;  2CMA A;  3D9C A;  3F41 A;  2Y2F A;  4D3Q A;  2CM8 A;  3O4S A;  3H2X A;  4YAA A;  2GP0 A;  1PA1 A;  5KA3 A;  2ZMM A;  1YGU A;  4OHL A;  2G6Z A;  3QCL A;  2CM3 A;  1NNY A;  4QAH A;  4NWG A;  1YTN A;  2FJN A;  2Q05 A;  1G7F A;  2GWO A;  4IKC A;  3RZ2 A;  3I80 A;  5BUG A;  2OC3 A;  2HCM A;  2R0B A;  1EEO A;  4QAP A;  4RKK A;  5EHP A;  2QDP A;  1KAK A;  2HC1 A;  5KA0 A;  1PTV A;  2AZR A;  2QBP A;  4WOH A;  3QCF A;  1LAR A;  2CFV A;  1ZC0 A;  2ZN7 A;  3PS5 A;  1OHC A;  3D1O A;  3QCI A;  2ESB A;  4BJO A;  1OHD A;  2I1Y A;  1Q6N A;  1Q6T A;  2B4U A;  3QCC A;  3D1H A;  5K23 A;  4J51 A;  1OEU A;  4WU2 A;  2NTA A;  1XM2 A;  4GE2 A;  4AZ1 A;  3ZMP A;  2A3K A;  3MMJ A;  2HB1 A;  2CMB A;  2H02 A;  1C88 A;  3O4U A;  1I57 A;  2CNG A;  4ZI4 A;  3F81 A;  1C87 A;  1FPZ A;  1A5Y A;  2BZL A;  3I36 A;  3QCJ A;  1PYN A;  1G4U S;  5KA1 A;  2VEU A;  1YTS A;  2I4H A;  5AWX A;  3AWG A;  2B4S A;  3ZMQ A;  2Y96 A;  5J8R A;  2F6Y A;  4RHG A;  2PA5 A;  4WTY A;  3D42 A;  4HRF A;  4GRY A;  2HNQ A;  3QKQ A;  1ZZW A;  4JBC A;  3AWF A;  1NWL A;  2CNI A;  2CNE A;  2DXP A;  1T49 A;  2QEP A;  3EAX A;  4I8N A;  1C84 A;  5I6V A;  1VHR A;  2FH7 A;  1Q6M A;  2I4E A;  3S4E A;  2A8B A;  4H34 A;  4RH5 A;  1GFY A;  1OES A;  3BLT A;  2I6O A;  2CNH A;  5K24 A;  5K25 A;  5K9V A;  2J17 A;  5KA9 A;  4TVV A;  5KA4 A;  5KAC A;  1JLN A;  4NND A;  2HXP A;  5MMZ B;  2HY3 A;  2MBC A;  1YN9 A;  3ZM0 A;  2NLK A;  4ERC A;  1J4X A;  2B4P A;  3QCD A;  4RI4 A;  3O3L A;  3F9A A;  5IBS A;  1P15 A;  2I6P A;  2QBQ A;  1WRM A;  2QBS A;  1V3A A;  4NX8 A;  4D3R A;  2HNP A;  1C86 A;  2F70 A;  1XXV A;  3BM8 A;  1NZ7 A;  2H04 A;  4KYR A;  1PA9 A;  2F6T A;  3NME A;  2Q47 A;  2PT0 A;  3QCH A;  2F6F A;  1C83 A;  4JMK A;  2P6X A;  1BZJ A;  2VEW A;  2HC2 A;  3EMU A;  2OOQ A;  4D3P A;  2JJD A;  3OMH A;  3U96 A;  1NL9 A;  1FQ1 A;  4H1O A;  2G59 A;  1G4W R;  3OLR A;  1LYV A;  2H4V A;  2VEX A;  1EEN A;  2B3O A;  2BGD A;  1RPM A;  4OHE A;  1ONY A;  1ZCK A;  1L8K A;  2CMC A;  4PYH A;  2F71 A;  4NYH A;  3QCB A;  3BLU A;  1PH0 A;  2QCJ A;  1PXH A;  3S4O A;  1XBO A;  1YGR A;  1OHE A;  2I75 A;  1U24 A;  2PI7 A;  4QUM A;  3V0H A;  5HDE A;  1XRI A;  5GTJ A;  1M3G A;  1OEM X;  1MKP A;  1LQF A;  2GJT A;  1R6H A;  1BZC A;  2HVL A;  4BPC A;  1T48 A;  3RO1 A;  2E0T A;  1OET A;  4JMJ A;  3V0J A;  5BZZ A;  1Q6S A;  1U26 A;  1WCH A;  4QUN A;  2CJZ A;  4DGP A;  5BZX A;  4Z6B A;  1G1G A;  3ZM1 A;  1I9T A;  2F6W A;  3S3K A;  2I4G A;  1YZ4 A;  1G1H A;  1QXK A;  4GE6 A;  5M43 A;  2P4D A;  4RDD A;  4RH9 A;  3RGQ A;  2M3V A;  4HJP A;  3F99 A;  3QKP A;  2H4K A;  2PQ5 A;  5IBM A;  5KAA A;  3BRH A;  1KAV A;  5K9W A;  1BZH A;  2CM7 A;  2NV5 A;  1YPT A;  4R30 A;  3V0E A;  2B07 A;  1G1F A;  2J16 B;  3QCE A;  4YR8 B;  1ZCL A;  2I5X A;  3V0I A;  1YWF A;  5KAB A;  1X24 A;  1ONZ A;  4ZN5 A;  4HJQ A;  3V0G A;  2FJM A;  2I3R A;  2BGE A;  5KA7 A;  5LXQ B;  1OEV A;  4WU3 A;  3EZZ A;  4S0G A;  2NT7 A;  3S3E A;  2I6M A;  4QBE A;  1PTU A;  1L8G A;  4DGX A;  1PTT A;  1SUG A;  1Q1M A;  2NT2 A;  2RF6 A;  3S3F A;  1FPR A;  4GS0 A;  1U25 A;  2OUD A;  2I6I A;  2I3U A;  1NO6 A;  4GFV A;  3LJ8 A;  4Y2E A;  3RGO A;  5BX1 A;  2I42 A;  2QBR A;  4OHH A;  4ZRT A;  2NZ6 A;  3QCN A;  4MBB A;  2B4O A;  1YTW A;  3A5J A;  2PBN A;  4OHI A;  1G7G A;  2BV5 A;  3ZM2 A;  2VEV A;  3EU0 A;  2YDU A;  1ECV A;  2WGP A;  2QCT A;  4R0T A;  3CM3 A;  4GFU A;  1JF7 A;  2BIJ A;  4RI5 A;  3ZM3 A;  2J16 A;  1D5R A;  5EHR A;  4R0S A;  3V0D A;  1PTY A;  4ICZ A;  4OHD A;  2F6Z A;  2CM2 A;  3I7Z A;  3O5X A;  3QCK A;  4JNB A;  1RXD A;  3AWE A;  1OEO X;  4KI9 A;  5K22 A;  1YFO A;  2QDC A;  2VEY A;  3V0F A;  1QZ0 A;  1C85 A;  1WAX A;  4QBW A;  1Q6J A;  3F9B A;  3QCG A;  4KYQ A;  4B04 A;  3GXH A;  3SME A;  2H4G A;  3M4U A;  3S3H A;  3A5K A;  3ZV2 A;  3B7O A;  3MOZ A;  5KA8 A;  4GWF A;  2B49 A;  5KAD A;  3D1Q A;  2C7S A;  3EB1 A;  2QDM A;  2F46 A;  3D44 A;  1Q6P A;  1T4J A;  3MOW A;  2OZ5 A;  4GRZ A;  3SR9 A;  3GXG A;  5KA2 A;  3QCM A;  2F6V A;  2C46 A;  1I9S A;  2H03 A;  2PSZ A;  4GE5 A;  1XXP A; 
#chains in the Genus database with same CATH topology
 4PVG A;  2I6J A;  4NWF A;  1E0D A;  2SHP A;  4Y14 A;  2IMG A;  2CNF A;  1GQY A;  1GWZ A;  2AHS A;  3N0A A;  3CWE A;  3O4T A;  1AAX A;  1NWE A;  2CMA A;  3D9C A;  3F41 A;  2Y2F A;  4D3Q A;  4BUC A;  3N2A A;  2CM8 A;  3O4S A;  3H2X A;  4YAA A;  2GP0 A;  1PA1 A;  5KA3 A;  1W78 A;  2ZMM A;  1YGU A;  2GCA A;  4OHL A;  2JFF A;  2G6Z A;  3HN7 A;  3QCL A;  2CM3 A;  1NNY A;  4QAH A;  4NWG A;  1YTN A;  2FJN A;  2Q05 A;  1G7F A;  2AM2 A;  2GWO A;  4IKC A;  3RZ2 A;  3I80 A;  5BUG A;  2OC3 A;  2HCM A;  2R0B A;  1EEO A;  4QAP A;  4RKK A;  5EHP A;  2QDP A;  1KAK A;  2HC1 A;  5KA0 A;  1PTV A;  2AZR A;  2QBP A;  4WOH A;  3QCF A;  4CVL A;  1LAR A;  2CFV A;  1ZC0 A;  2F00 A;  2ZN7 A;  3PS5 A;  1OHC A;  3D1O A;  3QCI A;  2ESB A;  4BJO A;  1OHD A;  2I1Y A;  1GG4 A;  1Q6N A;  1Q6T A;  2B4U A;  3QCC A;  3D1H A;  5K23 A;  4J51 A;  1OEU A;  4WU2 A;  2NTA A;  1XM2 A;  4GE2 A;  4AZ1 A;  3ZMP A;  2A3K A;  2WJP A;  3MMJ A;  2HB1 A;  2CMB A;  2H02 A;  1C88 A;  3O4U A;  1I57 A;  2CNG A;  4ZI4 A;  3F81 A;  1C87 A;  4ZIY A;  1FPZ A;  1A5Y A;  2BZL A;  3I36 A;  3QCJ A;  1PYN A;  2XPC A;  1G4U S;  3ZM5 A;  1W7K A;  5KA1 A;  2VEU A;  1YTS A;  2I4H A;  5AWX A;  3AWG A;  3NRS A;  2B4S A;  2GC6 A;  3ZMQ A;  2Y96 A;  5J8R A;  2F6Y A;  4RHG A;  2PA5 A;  4HV4 A;  4WTY A;  3D42 A;  4HRF A;  4GRY A;  2HNQ A;  3QKQ A;  1ZZW A;  4JBC A;  3AWF A;  1NWL A;  2CNI A;  2AM1 A;  2CNE A;  2DXP A;  1T49 A;  2VTD A;  2QEP A;  4CVM A;  3EAX A;  4I8N A;  1C84 A;  5I6V A;  1VHR A;  2FH7 A;  1Q6M A;  2I4E A;  3S4E A;  2A8B A;  4H34 A;  4RH5 A;  1GFY A;  1OES A;  3BLT A;  2I6O A;  2CNH A;  5K24 A;  5K25 A;  5K9V A;  2J17 A;  5KA9 A;  4TVV A;  5KA4 A;  5KAC A;  1JLN A;  4NND A;  2HXP A;  5MMZ B;  2HY3 A;  2MBC A;  1YN9 A;  3ZM0 A;  2NLK A;  4ERC A;  1J4X A;  2B4P A;  3QCD A;  4RI4 A;  3O3L A;  3F9A A;  5IBS A;  1P15 A;  2I6P A;  2QBQ A;  1WRM A;  2QBS A;  1V3A A;  4NX8 A;  4D3R A;  2HNP A;  1C86 A;  2F70 A;  1XXV A;  3BM8 A;  1NZ7 A;  1J6U A;  2H04 A;  4KYR A;  1PA9 A;  2F6T A;  3NME A;  3ZL8 A;  1O5Z A;  2UUP A;  2Q47 A;  2PT0 A;  3QCH A;  2F6F A;  3MVN A;  1C83 A;  4JMK A;  2P6X A;  1BZJ A;  2WTZ A;  2VEW A;  2HC2 A;  3EMU A;  2OOQ A;  4D3P A;  2JJD A;  2VOR A;  2GC5 A;  3OMH A;  3U96 A;  1UAG A;  1NL9 A;  1FQ1 A;  4H1O A;  2G59 A;  1G4W R;  3OLR A;  4UAG A;  1LYV A;  2H4V A;  2JFH A;  2VEX A;  1EEN A;  2B3O A;  2BGD A;  1RPM A;  4OHE A;  1ONY A;  1ZCK A;  1L8K A;  2CMC A;  4PYH A;  2F71 A;  4NYH A;  3QCB A;  3BLU A;  1PH0 A;  2QCJ A;  2UUO A;  1PXH A;  3S4O A;  1XBO A;  5A5F A;  1YGR A;  1OHE A;  2I75 A;  1U24 A;  2PI7 A;  4QUM A;  3V0H A;  5HDE A;  2JFG A;  1XRI A;  5GTJ A;  1M3G A;  1OEM X;  1MKP A;  1LQF A;  2GJT A;  1R6H A;  1JBW A;  1BZC A;  2HVL A;  4BPC A;  2Y67 A;  1FGS A;  1T48 A;  3RO1 A;  2E0T A;  1OET A;  4JMJ A;  3V0J A;  5BZZ A;  1Q6S A;  1U26 A;  2GCB A;  1WCH A;  4QUN A;  2CJZ A;  4DGP A;  5BZX A;  4Z6B A;  1G1G A;  3ZM1 A;  1I9T A;  2F6W A;  2Y66 A;  3S3K A;  2I4G A;  1YZ4 A;  1G1H A;  1QXK A;  4C13 A;  4GE6 A;  5M43 A;  2P4D A;  4RDD A;  4RH9 A;  3RGQ A;  3QCZ A;  3PYZ A;  2M3V A;  4HJP A;  3F99 A;  3QKP A;  2H4K A;  2PQ5 A;  5IBM A;  5KAA A;  3BRH A;  1KAV A;  5K9W A;  1BZH A;  2CM7 A;  2NV5 A;  1YPT A;  2VTE A;  4R30 A;  3V0E A;  2B07 A;  1G1F A;  2J16 B;  3QCE A;  4YR8 B;  1GQQ A;  1ZCL A;  2I5X A;  3V0I A;  3UAG A;  1YWF A;  5KAB A;  1X24 A;  1ONZ A;  4ZN5 A;  4HJQ A;  3V0G A;  2FJM A;  2I3R A;  2BGE A;  5KA7 A;  5LXQ B;  1OEV A;  4WU3 A;  3EZZ A;  4S0G A;  2NT7 A;  3S3E A;  5A5E A;  2I6M A;  4QBE A;  1PTU A;  1L8G A;  4DGX A;  1PTT A;  1SUG A;  1Q1M A;  2NT2 A;  2RF6 A;  3S3F A;  1FPR A;  4GS0 A;  1U25 A;  2OUD A;  2I6I A;  2I3U A;  1NO6 A;  1EEH A;  4GFV A;  3LJ8 A;  4Y2E A;  3RGO A;  5BX1 A;  1JBV A;  2I42 A;  2QBR A;  2X5O A;  4CVK A;  4OHH A;  4ZRT A;  2NZ6 A;  3QCN A;  4MBB A;  2B4O A;  1YTW A;  3A5J A;  2PBN A;  4OHI A;  1G7G A;  2BV5 A;  3ZM2 A;  2VEV A;  3EU0 A;  3ZM6 A;  2YDU A;  1ECV A;  2WGP A;  4BUB A;  2UAG A;  2QCT A;  4R0T A;  3CM3 A;  4GFU A;  1JF7 A;  2BIJ A;  2XJA A;  4RI5 A;  3ZM3 A;  2J16 A;  1D5R A;  5EHR A;  4R0S A;  3V0D A;  2VOS A;  1P31 A;  1PTY A;  4ICZ A;  4OHD A;  2F6Z A;  2CM2 A;  3I7Z A;  3O5X A;  3QCK A;  4QF5 A;  4JNB A;  1RXD A;  3AWE A;  1OEO X;  4KI9 A;  5K22 A;  2Y68 A;  1YFO A;  2QDC A;  2VEY A;  3V0F A;  1QZ0 A;  1C85 A;  1WAX A;  3LK7 A;  4QBW A;  1Q6J A;  3F9B A;  3QCG A;  4KYQ A;  4B04 A;  3GXH A;  3SME A;  2H4G A;  3M4U A;  3S3H A;  3A5K A;  3ZV2 A;  3B7O A;  3MOZ A;  2Y1O A;  5KA8 A;  4QDI A;  4GWF A;  2B49 A;  5KAD A;  3D1Q A;  2C7S A;  3EB1 A;  2QDM A;  2F46 A;  3D44 A;  1E8C A;  1Q6P A;  1T4J A;  3MOW A;  2OZ5 A;  4GRZ A;  3SR9 A;  3GXG A;  5KA2 A;  3QCM A;  4C12 A;  2F6V A;  1P3D A;  2C46 A;  1I9S A;  2H03 A;  2PSZ A;  4GE5 A;  1XXP A; 
#chains in the Genus database with same CATH homology
 4PVG A;  2I6J A;  4NWF A;  2SHP A;  4Y14 A;  2IMG A;  2CNF A;  1GWZ A;  2AHS A;  3N0A A;  3CWE A;  3O4T A;  1AAX A;  1NWE A;  2CMA A;  3D9C A;  3F41 A;  2Y2F A;  4D3Q A;  2CM8 A;  3O4S A;  3H2X A;  4YAA A;  2GP0 A;  1PA1 A;  5KA3 A;  2ZMM A;  1YGU A;  4OHL A;  2G6Z A;  3QCL A;  2CM3 A;  1NNY A;  4QAH A;  4NWG A;  1YTN A;  2FJN A;  2Q05 A;  1G7F A;  2GWO A;  4IKC A;  3RZ2 A;  3I80 A;  5BUG A;  2OC3 A;  2HCM A;  2R0B A;  1EEO A;  4QAP A;  4RKK A;  5EHP A;  2QDP A;  1KAK A;  2HC1 A;  5KA0 A;  1PTV A;  2AZR A;  2QBP A;  4WOH A;  3QCF A;  1LAR A;  2CFV A;  1ZC0 A;  2ZN7 A;  3PS5 A;  1OHC A;  3D1O A;  3QCI A;  2ESB A;  4BJO A;  1OHD A;  2I1Y A;  1Q6N A;  1Q6T A;  2B4U A;  3QCC A;  3D1H A;  5K23 A;  4J51 A;  1OEU A;  4WU2 A;  2NTA A;  1XM2 A;  4GE2 A;  4AZ1 A;  3ZMP A;  2A3K A;  3MMJ A;  2HB1 A;  2CMB A;  2H02 A;  1C88 A;  3O4U A;  1I57 A;  2CNG A;  4ZI4 A;  3F81 A;  1C87 A;  1FPZ A;  1A5Y A;  2BZL A;  3I36 A;  3QCJ A;  1PYN A;  1G4U S;  5KA1 A;  2VEU A;  1YTS A;  2I4H A;  5AWX A;  3AWG A;  2B4S A;  3ZMQ A;  2Y96 A;  5J8R A;  2F6Y A;  4RHG A;  2PA5 A;  4WTY A;  3D42 A;  4HRF A;  4GRY A;  2HNQ A;  3QKQ A;  1ZZW A;  4JBC A;  3AWF A;  1NWL A;  2CNI A;  2CNE A;  2DXP A;  1T49 A;  2QEP A;  3EAX A;  4I8N A;  1C84 A;  5I6V A;  1VHR A;  2FH7 A;  1Q6M A;  2I4E A;  3S4E A;  2A8B A;  4H34 A;  4RH5 A;  1GFY A;  1OES A;  3BLT A;  2I6O A;  2CNH A;  5K24 A;  5K25 A;  5K9V A;  2J17 A;  5KA9 A;  4TVV A;  5KA4 A;  5KAC A;  1JLN A;  4NND A;  2HXP A;  5MMZ B;  2HY3 A;  2MBC A;  1YN9 A;  3ZM0 A;  2NLK A;  4ERC A;  1J4X A;  2B4P A;  3QCD A;  4RI4 A;  3O3L A;  3F9A A;  5IBS A;  1P15 A;  2I6P A;  2QBQ A;  1WRM A;  2QBS A;  1V3A A;  4NX8 A;  4D3R A;  2HNP A;  1C86 A;  2F70 A;  1XXV A;  3BM8 A;  1NZ7 A;  2H04 A;  4KYR A;  1PA9 A;  2F6T A;  3NME A;  2Q47 A;  2PT0 A;  3QCH A;  2F6F A;  1C83 A;  4JMK A;  2P6X A;  1BZJ A;  2VEW A;  2HC2 A;  3EMU A;  2OOQ A;  4D3P A;  2JJD A;  3OMH A;  3U96 A;  1NL9 A;  1FQ1 A;  4H1O A;  2G59 A;  1G4W R;  3OLR A;  1LYV A;  2H4V A;  2VEX A;  1EEN A;  2B3O A;  2BGD A;  1RPM A;  4OHE A;  1ONY A;  1ZCK A;  1L8K A;  2CMC A;  4PYH A;  2F71 A;  4NYH A;  3QCB A;  3BLU A;  1PH0 A;  2QCJ A;  1PXH A;  3S4O A;  1XBO A;  1YGR A;  1OHE A;  2I75 A;  1U24 A;  2PI7 A;  4QUM A;  3V0H A;  5HDE A;  1XRI A;  5GTJ A;  1M3G A;  1OEM X;  1MKP A;  1LQF A;  2GJT A;  1R6H A;  1BZC A;  2HVL A;  4BPC A;  1T48 A;  3RO1 A;  2E0T A;  1OET A;  4JMJ A;  3V0J A;  5BZZ A;  1Q6S A;  1U26 A;  1WCH A;  4QUN A;  2CJZ A;  4DGP A;  5BZX A;  4Z6B A;  1G1G A;  3ZM1 A;  1I9T A;  2F6W A;  3S3K A;  2I4G A;  1YZ4 A;  1G1H A;  1QXK A;  4GE6 A;  5M43 A;  2P4D A;  4RDD A;  4RH9 A;  3RGQ A;  2M3V A;  4HJP A;  3F99 A;  3QKP A;  2H4K A;  2PQ5 A;  5IBM A;  5KAA A;  3BRH A;  1KAV A;  5K9W A;  1BZH A;  2CM7 A;  2NV5 A;  1YPT A;  4R30 A;  3V0E A;  2B07 A;  1G1F A;  2J16 B;  3QCE A;  4YR8 B;  1ZCL A;  2I5X A;  3V0I A;  1YWF A;  5KAB A;  1X24 A;  1ONZ A;  4ZN5 A;  4HJQ A;  3V0G A;  2FJM A;  2I3R A;  2BGE A;  5KA7 A;  5LXQ B;  1OEV A;  4WU3 A;  3EZZ A;  4S0G A;  2NT7 A;  3S3E A;  2I6M A;  4QBE A;  1PTU A;  1L8G A;  4DGX A;  1PTT A;  1SUG A;  1Q1M A;  2NT2 A;  2RF6 A;  3S3F A;  1FPR A;  4GS0 A;  1U25 A;  2OUD A;  2I6I A;  2I3U A;  1NO6 A;  4GFV A;  3LJ8 A;  4Y2E A;  3RGO A;  5BX1 A;  2I42 A;  2QBR A;  4OHH A;  4ZRT A;  2NZ6 A;  3QCN A;  4MBB A;  2B4O A;  1YTW A;  3A5J A;  2PBN A;  4OHI A;  1G7G A;  2BV5 A;  3ZM2 A;  2VEV A;  3EU0 A;  2YDU A;  1ECV A;  2WGP A;  2QCT A;  4R0T A;  3CM3 A;  4GFU A;  1JF7 A;  2BIJ A;  4RI5 A;  3ZM3 A;  2J16 A;  1D5R A;  5EHR A;  4R0S A;  3V0D A;  1PTY A;  4ICZ A;  4OHD A;  2F6Z A;  2CM2 A;  3I7Z A;  3O5X A;  3QCK A;  4JNB A;  1RXD A;  3AWE A;  1OEO X;  4KI9 A;  5K22 A;  1YFO A;  2QDC A;  2VEY A;  3V0F A;  1QZ0 A;  1C85 A;  1WAX A;  4QBW A;  1Q6J A;  3F9B A;  3QCG A;  4KYQ A;  4B04 A;  3GXH A;  3SME A;  2H4G A;  3M4U A;  3S3H A;  3A5K A;  3ZV2 A;  3B7O A;  3MOZ A;  5KA8 A;  4GWF A;  2B49 A;  5KAD A;  3D1Q A;  2C7S A;  3EB1 A;  2QDM A;  2F46 A;  3D44 A;  1Q6P A;  1T4J A;  3MOW A;  2OZ5 A;  4GRZ A;  3SR9 A;  3GXG A;  5KA2 A;  3QCM A;  2F6V A;  2C46 A;  1I9S A;  2H03 A;  2PSZ A;  4GE5 A;  1XXP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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