1KAKA

Human tyrosine phosphatase 1b complexed with an inhibitor
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
total genus 99
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2001-11-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1kakA00
3F99A 4ERCA 2QEPA 2VEUA 2I5XA 5BZZA 2GWOA 1YPTA 3GXGA 2ZN7A 2OC3A 1U24A 3O4TA 4BPCA 1T49A 4OHIA 4ZRTA 3QCFA 5M43A 4NWFA 3QCIA 4JBCA 4JMKA 3V0IA 1FPRA 2H02A 4OHDA 1G4WR 1NZ7A 2I6JA 3BLUA 4OHEA 3QCHA 4JNBA 2H4KA 1C88A 1YTSA 3EB1A 4HJPA 1LQFA 2H03A 5GTJA 2I75A 4H1OA 2CM7A 3F9AA 2I4HA 2OOQA 1EENA 3S3FA 4BJOA 4NWGA 1ONZA 3S3EA 4QBWA 4R0TA 1L8KA 1WRMA 1NWEA 5KA9A 2SHPA 5KA0A 2CFVA 2F46A 2J16B 1PA1A 2F6YA 3SMEA 2AHSA 4RI5A 2GJTA 2VEVA 1PTYA 3ZM0A 2HB1A 3ZM2A 3V0GA 3F41A 1A5YA 4KYRA 2IMGA 1YTNA 3U96A 4ZN5A 5LXQB 2QBQA 1XXPA 3A5JA 3A5KA 2CM2A 3O5XA 1X24A 3O4UA 4KI9A 5KAAA 1OEOX 2CMAA 2QBSA 2HNPA 1JLNA 5KADA 1QXKA 1LYVA 2QDPA 4PYHA 1XRIA 1V3AA 3CWEA 5KABA 2I3RA 2PA5A 5K9VA 2F70A 1XM2A 1YN9A 2CMCA 4QAHA 5K25A 5HDEA 3RZ2A 5MMZB 3EMUA 4RH5A 3MOZA 2B4SA 3EAXA 2F6TA 2MBCA 4GFVA 1NNYA 3D1OA 3V0JA 2B4PA 2RF6A 3ZV2A 4J51A 4ZI4A 2I4GA 1R6HA 2NV5A 3QCDA 4D3RA 3B7OA 3BM8A 2I6MA 1PYNA 4WU3A 1RXDA 2VEXA 4GE2A 1OEUA 4ICZA 2P6XA 5I6VA 1PXHA 1G7FA 1BZCA 2VEWA 3OLRA 1T48A 4GFUA 2NZ6A 1C87A 2HNQA 2I4EA 2I3UA 3BLTA 3AWFA 4WTYA 2H4GA 2HXPA 1PTTA 5EHRA 1T4JA 5KA2A 1GFYA 1FPZA 2E0TA 2PBNA 3F9BA 4QUNA 3OMHA 4OHLA 2OUDA 2NLKA 2Y96A 5KACA 2FJNA 3S3HA 1XXVA 5KA4A 2J17A 2FH7A 1PTVA 3ZM1A 2YDUA 2CM8A 1OEMX 3N0AA 3O4SA 4JMJA 1C85A 4TVVA 4D3PA 4Y2EA 5KA7A 5KA3A 2ZMMA 2CNHA 4B04A 4GE5A 4WOHA 2BGEA 1PA9A 2C46A 2F6WA 4QAPA 2CJZA 3S3KA 1MKPA 4QUMA 4RI4A 1Q6NA 1PTUA 3D44A 5K24A 5K23A 1C84A 3D1HA 4OHHA 3D9CA 2ESBA 3V0EA 1LARA 3V0HA 1ZC0A 2G6ZA 1ZCKA 3LJ8A 1J4XA 2G59A 1JF7A 1KAVA 4YR8B 1GWZA 1ZZWA 3QCMA 3QCCA 2J16A 3V0DA 1OETA 1WCHA 1Q6JA 1RPMA 1Q1MA 2QBRA 2R0BA 2I6PA 3QCLA 4IKCA 2QDMA 3CM3A 5AWXA 3RGQA 2JJDA 2C7SA 2Q05A 2HC2A 4NNDA 4RHGA 1I9SA 1YGRA 2Q47A 1OHEA 2Y2FA 3QCBA 2CNGA 2QBPA 3BRHA 3EU0A 5K9WA 1YTWA 1U26A 2M3VA 2QCTA 2F6VA 1EEOA 1PH0A 1D5RA 1VHRA 1G1GA 2HCMA 4WU2A 3QCGA 1Q6PA 2I6IA 2H04A 1P15A 1BZJA 4HJQA 1NWLA 4D3QA 4DGXA 3D1QA 4R0SA 5IBSA 3QCEA 3F81A 1OHDA 2WGPA 5J8RA 1M3GA 4S0GA 3MMJA 2B07A 4HRFA 2B3OA 2A3KA 2VEYA 3I7ZA 3QCNA 2CNEA 3O3LA 3QCKA 2AZRA 1U25A 1G1HA 2PT0A 2NT2A 2NTAA 3ZM3A 2FJMA 2CM3A 2F71A 1OHCA 5KA8A 1I9TA 2B4OA 2BV5A 4R30A 1C86A 5EHPA 3AWEA 2BIJA 2BGDA 4PVGA 3EZZA 4H34A 2HY3A 4GWFA 1NL9A 4QBEA 4Y14A 2DXPA 1YFOA 4RKKA 4KYQA 2QDCA 4MBBA 3SR9A 1Q6MA 1XBOA 2BZLA 4I8NA 3AWGA 1L8GA 5BZXA 1YWFA 5IBMA 2OZ5A 1I57A 2B4UA 1G4US 2PI7A 1G7GA 4Z6BA 1ZCLA 3GXHA 4GRZA 4NYHA 2HVLA 4DGPA 1BZHA 3ZMQA 1Q6TA 1G1FA 2PQ5A 1QZ0A 3M4UA 1NO6A 3NMEA 3H2XA 5K22A 2B49A 1FQ1A 3S4EA 4RDDA 1OESA 1SUGA 4RH9A 1ECVA 2F6FA 3MOWA 3PS5A 4GE6A 2A8BA 1AAXA 3RGOA 1WAXA 3ZMPA 3D42A 3QCJA 1KAKA 2QCJA 3S4OA 2P4DA 4GS0A 1OEVA 2F6ZA 2H4VA 1YZ4A 3V0FA 4GRYA 2GP0A 3I36A 2I1YA 3RO1A 3I80A 4YAAA 3QKPA 2PSZA 1YGUA 4AZ1A 2CNFA 1ONYA 4NX8A 5KA1A 5BX1A 2CMBA 2I42A 2I6OA 2NT7A 3QKQA 2CNIA 2HC1A 1Q6SA 5BUGA 1C83A
chains in the Genus database with same CATH superfamily
3F99A 4ERCA 2QEPA 4QDIA 2VEUA 2I5XA 5BZZA 2VORA 1J6UA 2GWOA 1YPTA 3GXGA 2ZN7A 2OC3A 1U24A 3O4TA 4BPCA 1T49A 4OHIA 4ZRTA 3QCFA 5M43A 4NWFA 3QCIA 4JBCA 4JMKA 3V0IA 1FPRA 2H02A 4OHDA 1G4WR 1NZ7A 2I6JA 3HN7A 3BLUA 4OHEA 3QCHA 4JNBA 2H4KA 1C88A 1YTSA 3EB1A 4HJPA 1LQFA 2H03A 5GTJA 2I75A 4H1OA 2CM7A 3F9AA 2I4HA 2OOQA 1EENA 3S3FA 4BJOA 2Y1OA 4NWGA 1ONZA 1O5ZA 3S3EA 4QBWA 4R0TA 1L8KA 1WRMA 1NWEA 5KA9A 5A5EA 2SHPA 5KA0A 3UAGA 2CFVA 2F46A 2GCAA 2J16B 1PA1A 2F6YA 3SMEA 2AM1A 2AHSA 4RI5A 2GJTA 2VEVA 1PTYA 3ZM0A 2HB1A 2JFFA 2Y67A 3ZM2A 3V0GA 3F41A 1A5YA 4KYRA 2XPCA 2IMGA 1YTNA 3U96A 4ZN5A 5LXQB 2QBQA 4BUCA 1XXPA 3A5JA 3A5KA 2CM2A 3O5XA 1X24A 3O4UA 4KI9A 5KAAA 1OEOX 2CMAA 2QBSA 2HNPA 1JLNA 2X5OA 1QXKA 5KADA 1LYVA 2QDPA 4PYHA 1XRIA 1V3AA 3CWEA 3LK7A 5KABA 2I3RA 2PA5A 5K9VA 2XJAA 3NRSA 2F70A 1XM2A 1YN9A 2CMCA 4QAHA 5K25A 1JBVA 5HDEA 3RZ2A 5MMZB 3EMUA 4RH5A 3MOZA 2B4SA 3EAXA 2F6TA 2MBCA 4GFVA 1NNYA 3D1OA 3V0JA 2B4PA 2RF6A 3ZV2A 1EEHA 4J51A 4BUBA 4ZI4A 2I4GA 1R6HA 2NV5A 3QCDA 4D3RA 3B7OA 3BM8A 2I6MA 1PYNA 4WU3A 2AM2A 1RXDA 2VEXA 4GE2A 2F00A 3ZM6A 1OEUA 4ICZA 2P6XA 2Y68A 5I6VA 1PXHA 1G7FA 1BZCA 2GCBA 2VEWA 3OLRA 1T48A 4GFUA 2NZ6A 1C87A 2HNQA 2I4EA 2I3UA 3BLTA 3AWFA 4CVKA 4WTYA 2H4GA 2HXPA 1PTTA 5EHRA 1T4JA 5KA2A 1GFYA 1FPZA 2E0TA 2PBNA 3F9BA 4QUNA 3OMHA 4OHLA 2OUDA 2NLKA 2Y96A 5KACA 2FJNA 3S3HA 1XXVA 5KA4A 2J17A 2UAGA 2FH7A 1PTVA 3ZM1A 2YDUA 2CM8A 1OEMX 3N0AA 3O4SA 4JMJA 1C85A 4TVVA 4D3PA 4Y2EA 5KA7A 5KA3A 2ZMMA 2CNHA 4B04A 4GE5A 4WOHA 2BGEA 1PA9A 2C46A 2F6WA 4QAPA 2CJZA 3S3KA 2VTDA 1MKPA 4QUMA 4RI4A 1Q6NA 1PTUA 3D44A 5K24A 1W78A 5K23A 1C84A 3D1HA 4OHHA 3D9CA 2ESBA 3V0EA 1LARA 3V0HA 1GQQA 1ZC0A 2G6ZA 1ZCKA 3LJ8A 1J4XA 2G59A 1JF7A 1KAVA 4YR8B 1GWZA 1ZZWA 3QCMA 2GC5A 3QCCA 2J16A 3V0DA 1OETA 1WCHA 1Q6JA 4CVMA 1RPMA 1Q1MA 2QBRA 2R0BA 2I6PA 3QCLA 4IKCA 2QDMA 3CM3A 5AWXA 3RGQA 2JJDA 2C7SA 2Q05A 2HC2A 4NNDA 1JBWA 2Y66A 4RHGA 1I9SA 1P3DA 4C12A 1YGRA 2Q47A 1OHEA 2Y2FA 3QCBA 2CNGA 2QBPA 3BRHA 3EU0A 5K9WA 1YTWA 1U26A 2M3VA 2QCTA 2F6VA 1EEOA 1PH0A 1D5RA 1VHRA 1G1GA 2HCMA 3ZM5A 4WU2A 2WJPA 3QCGA 1Q6PA 2I6IA 2H04A 1P15A 4UAGA 1BZJA 3N2AA 4HJQA 1NWLA 4D3QA 4DGXA 2UUPA 3D1QA 4R0SA 1W7KA 2JFGA 2GC6A 5IBSA 3QCEA 3F81A 1OHDA 2WGPA 5J8RA 1M3GA 3MVNA 4S0GA 3MMJA 2B07A 4HRFA 2VOSA 2B3OA 2A3KA 2VEYA 3ZL8A 3I7ZA 3QCNA 2CNEA 3O3LA 3QCKA 2AZRA 1U25A 1G1HA 2PT0A 2NT2A 2NTAA 3ZM3A 2FJMA 2CM3A 3QCZA 2F71A 1OHCA 5KA8A 1I9TA 2B4OA 2BV5A 4R30A 1C86A 5EHPA 3AWEA 4QF5A 2BIJA 5A5FA 2BGDA 4PVGA 4CVLA 3EZZA 4H34A 2HY3A 4GWFA 1NL9A 4QBEA 4Y14A 2WTZA 2DXPA 1YFOA 4RKKA 4KYQA 2QDCA 2UUOA 4MBBA 3SR9A 1Q6MA 1XBOA 2BZLA 4I8NA 3AWGA 1L8GA 5BZXA 1YWFA 5IBMA 2OZ5A 1I57A 2B4UA 1G4US 1E0DA 2PI7A 1G7GA 4Z6BA 1ZCLA 4C13A 1P31A 3GXHA 4GRZA 4NYHA 4HV4A 2HVLA 4DGPA 1BZHA 1UAGA 3ZMQA 1Q6TA 1E8CA 1G1FA 2PQ5A 1QZ0A 3M4UA 1NO6A 3NMEA 3H2XA 5K22A 2B49A 1FQ1A 3S4EA 4RDDA 1OESA 1SUGA 2VTEA 4RH9A 1ECVA 2F6FA 3MOWA 3PS5A 4GE6A 2A8BA 1GG4A 1AAXA 3RGOA 1WAXA 4ZIYA 3ZMPA 3D42A 3QCJA 1KAKA 1FGSA 2QCJA 3S4OA 2P4DA 4GS0A 1OEVA 2F6ZA 2H4VA 1YZ4A 3V0FA 4GRYA 2GP0A 3I36A 2I1YA 3RO1A 3I80A 4YAAA 3QKPA 2PSZA 3PYZA 1YGUA 4AZ1A 2CNFA 1ONYA 4NX8A 5KA1A 5BX1A 2CMBA 2I42A 2I6OA 2NT7A 1GQYA 3QKQA 2CNIA 2HC1A 1Q6SA 5BUGA 2JFHA 1C83A
chains in the Genus database with same CATH topology
3F99A 4ERCA 2QEPA 2VEUA 2I5XA 5BZZA 2GWOA 1YPTA 3GXGA 2ZN7A 2OC3A 1U24A 3O4TA 4BPCA 1T49A 4OHIA 4ZRTA 3QCFA 5M43A 4NWFA 3QCIA 4JBCA 4JMKA 3V0IA 1FPRA 2H02A 4OHDA 1G4WR 1NZ7A 2I6JA 3BLUA 4OHEA 3QCHA 4JNBA 2H4KA 1C88A 1YTSA 3EB1A 4HJPA 1LQFA 2H03A 5GTJA 2I75A 4H1OA 2CM7A 3F9AA 2I4HA 2OOQA 1EENA 3S3FA 4BJOA 4NWGA 1ONZA 3S3EA 4QBWA 4R0TA 1L8KA 1WRMA 1NWEA 5KA9A 2SHPA 5KA0A 2CFVA 2F46A 2J16B 1PA1A 2F6YA 3SMEA 2AHSA 4RI5A 2GJTA 2VEVA 1PTYA 3ZM0A 2HB1A 3ZM2A 3V0GA 3F41A 1A5YA 4KYRA 2IMGA 1YTNA 3U96A 4ZN5A 5LXQB 2QBQA 1XXPA 3A5JA 3A5KA 2CM2A 3O5XA 1X24A 3O4UA 4KI9A 5KAAA 1OEOX 2CMAA 2QBSA 2HNPA 1JLNA 5KADA 1QXKA 1LYVA 2QDPA 4PYHA 1XRIA 1V3AA 3CWEA 5KABA 2I3RA 2PA5A 5K9VA 2F70A 1XM2A 1YN9A 2CMCA 4QAHA 5K25A 5HDEA 3RZ2A 5MMZB 3EMUA 4RH5A 3MOZA 2B4SA 3EAXA 2F6TA 2MBCA 4GFVA 1NNYA 3D1OA 3V0JA 2B4PA 2RF6A 3ZV2A 4J51A 4ZI4A 2I4GA 1R6HA 2NV5A 3QCDA 4D3RA 3B7OA 3BM8A 2I6MA 1PYNA 4WU3A 1RXDA 2VEXA 4GE2A 1OEUA 4ICZA 2P6XA 5I6VA 1PXHA 1G7FA 1BZCA 2VEWA 3OLRA 1T48A 4GFUA 2NZ6A 1C87A 2HNQA 2I4EA 2I3UA 3BLTA 3AWFA 4WTYA 2H4GA 2HXPA 1PTTA 5EHRA 1T4JA 5KA2A 1GFYA 1FPZA 2E0TA 2PBNA 3F9BA 4QUNA 3OMHA 4OHLA 2OUDA 2NLKA 2Y96A 5KACA 2FJNA 3S3HA 1XXVA 5KA4A 2J17A 2FH7A 1PTVA 3ZM1A 2YDUA 2CM8A 1OEMX 3N0AA 3O4SA 4JMJA 1C85A 4TVVA 4D3PA 4Y2EA 5KA7A 5KA3A 2ZMMA 2CNHA 4B04A 4GE5A 4WOHA 2BGEA 1PA9A 2C46A 2F6WA 4QAPA 2CJZA 3S3KA 1MKPA 4QUMA 4RI4A 1Q6NA 1PTUA 3D44A 5K24A 5K23A 1C84A 3D1HA 4OHHA 3D9CA 2ESBA 3V0EA 1LARA 3V0HA 1ZC0A 2G6ZA 1ZCKA 3LJ8A 1J4XA 2G59A 1JF7A 1KAVA 4YR8B 1GWZA 1ZZWA 3QCMA 3QCCA 2J16A 3V0DA 1OETA 1WCHA 1Q6JA 1RPMA 1Q1MA 2QBRA 2R0BA 2I6PA 3QCLA 4IKCA 2QDMA 3CM3A 5AWXA 3RGQA 2JJDA 2C7SA 2Q05A 2HC2A 4NNDA 4RHGA 1I9SA 1YGRA 2Q47A 1OHEA 2Y2FA 3QCBA 2CNGA 2QBPA 3BRHA 3EU0A 5K9WA 1YTWA 1U26A 2M3VA 2QCTA 2F6VA 1EEOA 1PH0A 1D5RA 1VHRA 1G1GA 2HCMA 4WU2A 3QCGA 1Q6PA 2I6IA 2H04A 1P15A 1BZJA 4HJQA 1NWLA 4D3QA 4DGXA 3D1QA 4R0SA 5IBSA 3QCEA 3F81A 1OHDA 2WGPA 5J8RA 1M3GA 4S0GA 3MMJA 2B07A 4HRFA 2B3OA 2A3KA 2VEYA 3I7ZA 3QCNA 2CNEA 3O3LA 3QCKA 2AZRA 1U25A 1G1HA 2PT0A 2NT2A 2NTAA 3ZM3A 2FJMA 2CM3A 2F71A 1OHCA 5KA8A 1I9TA 2B4OA 2BV5A 4R30A 1C86A 5EHPA 3AWEA 2BIJA 2BGDA 4PVGA 3EZZA 4H34A 2HY3A 4GWFA 1NL9A 4QBEA 4Y14A 2DXPA 1YFOA 4RKKA 4KYQA 2QDCA 4MBBA 3SR9A 1Q6MA 1XBOA 2BZLA 4I8NA 3AWGA 1L8GA 5BZXA 1YWFA 5IBMA 2OZ5A 1I57A 2B4UA 1G4US 2PI7A 1G7GA 4Z6BA 1ZCLA 3GXHA 4GRZA 4NYHA 2HVLA 4DGPA 1BZHA 3ZMQA 1Q6TA 1G1FA 2PQ5A 1QZ0A 3M4UA 1NO6A 3NMEA 3H2XA 5K22A 2B49A 1FQ1A 3S4EA 4RDDA 1OESA 1SUGA 4RH9A 1ECVA 2F6FA 3MOWA 3PS5A 4GE6A 2A8BA 1AAXA 3RGOA 1WAXA 3ZMPA 3D42A 3QCJA 1KAKA 2QCJA 3S4OA 2P4DA 4GS0A 1OEVA 2F6ZA 2H4VA 1YZ4A 3V0FA 4GRYA 2GP0A 3I36A 2I1YA 3RO1A 3I80A 4YAAA 3QKPA 2PSZA 1YGUA 4AZ1A 2CNFA 1ONYA 4NX8A 5KA1A 5BX1A 2CMBA 2I42A 2I6OA 2NT7A 3QKQA 2CNIA 2HC1A 1Q6SA 5BUGA 1C83A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F99 A;  4ERC A;  2QEP A;  2VEU A;  2I5X A;  5BZZ A;  2GWO A;  1YPT A;  3GXG A;  2ZN7 A;  2OC3 A;  1U24 A;  3O4T A;  4BPC A;  1T49 A;  4OHI A;  4ZRT A;  3QCF A;  5M43 A;  4NWF A;  3QCI A;  4JBC A;  4JMK A;  3V0I A;  1FPR A;  2H02 A;  4OHD A;  1G4W R;  1NZ7 A;  2I6J A;  3BLU A;  4OHE A;  3QCH A;  4JNB A;  2H4K A;  1C88 A;  1YTS A;  3EB1 A;  4HJP A;  1LQF A;  2H03 A;  5GTJ A;  2I75 A;  4H1O A;  2CM7 A;  3F9A A;  2I4H A;  2OOQ A;  1EEN A;  3S3F A;  4BJO A;  4NWG A;  1ONZ A;  3S3E A;  4QBW A;  4R0T A;  1L8K A;  1WRM A;  1NWE A;  5KA9 A;  2SHP A;  5KA0 A;  2CFV A;  2F46 A;  2J16 B;  1PA1 A;  2F6Y A;  3SME A;  2AHS A;  4RI5 A;  2GJT A;  2VEV A;  1PTY A;  3ZM0 A;  2HB1 A;  3ZM2 A;  3V0G A;  3F41 A;  1A5Y A;  4KYR A;  2IMG A;  1YTN A;  3U96 A;  4ZN5 A;  5LXQ B;  2QBQ A;  1XXP A;  3A5J A;  3A5K A;  2CM2 A;  3O5X A;  1X24 A;  3O4U A;  4KI9 A;  5KAA A;  1OEO X;  2CMA A;  2QBS A;  2HNP A;  1JLN A;  5KAD A;  1QXK A;  1LYV A;  2QDP A;  4PYH A;  1XRI A;  1V3A A;  3CWE A;  5KAB A;  2I3R A;  2PA5 A;  5K9V A;  2F70 A;  1XM2 A;  1YN9 A;  2CMC A;  4QAH A;  5K25 A;  5HDE A;  3RZ2 A;  5MMZ B;  3EMU A;  4RH5 A;  3MOZ A;  2B4S A;  3EAX A;  2F6T A;  2MBC A;  4GFV A;  1NNY A;  3D1O A;  3V0J A;  2B4P A;  2RF6 A;  3ZV2 A;  4J51 A;  4ZI4 A;  2I4G A;  1R6H A;  2NV5 A;  3QCD A;  4D3R A;  3B7O A;  3BM8 A;  2I6M A;  1PYN A;  4WU3 A;  1RXD A;  2VEX A;  4GE2 A;  1OEU A;  4ICZ A;  2P6X A;  5I6V A;  1PXH A;  1G7F A;  1BZC A;  2VEW A;  3OLR A;  1T48 A;  4GFU A;  2NZ6 A;  1C87 A;  2HNQ A;  2I4E A;  2I3U A;  3BLT A;  3AWF A;  4WTY A;  2H4G A;  2HXP A;  1PTT A;  5EHR A;  1T4J A;  5KA2 A;  1GFY A;  1FPZ A;  2E0T A;  2PBN A;  3F9B A;  4QUN A;  3OMH A;  4OHL A;  2OUD A;  2NLK A;  2Y96 A;  5KAC A;  2FJN A;  3S3H A;  1XXV A;  5KA4 A;  2J17 A;  2FH7 A;  1PTV A;  3ZM1 A;  2YDU A;  2CM8 A;  1OEM X;  3N0A A;  3O4S A;  4JMJ A;  1C85 A;  4TVV A;  4D3P A;  4Y2E A;  5KA7 A;  5KA3 A;  2ZMM A;  2CNH A;  4B04 A;  4GE5 A;  4WOH A;  2BGE A;  1PA9 A;  2C46 A;  2F6W A;  4QAP A;  2CJZ A;  3S3K A;  1MKP A;  4QUM A;  4RI4 A;  1Q6N A;  1PTU A;  3D44 A;  5K24 A;  5K23 A;  1C84 A;  3D1H A;  4OHH A;  3D9C A;  2ESB A;  3V0E A;  1LAR A;  3V0H A;  1ZC0 A;  2G6Z A;  1ZCK A;  3LJ8 A;  1J4X A;  2G59 A;  1JF7 A;  1KAV A;  4YR8 B;  1GWZ A;  1ZZW A;  3QCM A;  3QCC A;  2J16 A;  3V0D A;  1OET A;  1WCH A;  1Q6J A;  1RPM A;  1Q1M A;  2QBR A;  2R0B A;  2I6P A;  3QCL A;  4IKC A;  2QDM A;  3CM3 A;  5AWX A;  3RGQ A;  2JJD A;  2C7S A;  2Q05 A;  2HC2 A;  4NND A;  4RHG A;  1I9S A;  1YGR A;  2Q47 A;  1OHE A;  2Y2F A;  3QCB A;  2CNG A;  2QBP A;  3BRH A;  3EU0 A;  5K9W A;  1YTW A;  1U26 A;  2M3V A;  2QCT A;  2F6V A;  1EEO A;  1PH0 A;  1D5R A;  1VHR A;  1G1G A;  2HCM A;  4WU2 A;  3QCG A;  1Q6P A;  2I6I A;  2H04 A;  1P15 A;  1BZJ A;  4HJQ A;  1NWL A;  4D3Q A;  4DGX A;  3D1Q A;  4R0S A;  5IBS A;  3QCE A;  3F81 A;  1OHD A;  2WGP A;  5J8R A;  1M3G A;  4S0G A;  3MMJ A;  2B07 A;  4HRF A;  2B3O A;  2A3K A;  2VEY A;  3I7Z A;  3QCN A;  2CNE A;  3O3L A;  3QCK A;  2AZR A;  1U25 A;  1G1H A;  2PT0 A;  2NT2 A;  2NTA A;  3ZM3 A;  2FJM A;  2CM3 A;  2F71 A;  1OHC A;  5KA8 A;  1I9T A;  2B4O A;  2BV5 A;  4R30 A;  1C86 A;  5EHP A;  3AWE A;  2BIJ A;  2BGD A;  4PVG A;  3EZZ A;  4H34 A;  2HY3 A;  4GWF A;  1NL9 A;  4QBE A;  4Y14 A;  2DXP A;  1YFO A;  4RKK A;  4KYQ A;  2QDC A;  4MBB A;  3SR9 A;  1Q6M A;  1XBO A;  2BZL A;  4I8N A;  3AWG A;  1L8G A;  5BZX A;  1YWF A;  5IBM A;  2OZ5 A;  1I57 A;  2B4U A;  1G4U S;  2PI7 A;  1G7G A;  4Z6B A;  1ZCL A;  3GXH A;  4GRZ A;  4NYH A;  2HVL A;  4DGP A;  1BZH A;  3ZMQ A;  1Q6T A;  1G1F A;  2PQ5 A;  1QZ0 A;  3M4U A;  1NO6 A;  3NME A;  3H2X A;  5K22 A;  2B49 A;  1FQ1 A;  3S4E A;  4RDD A;  1OES A;  1SUG A;  4RH9 A;  1ECV A;  2F6F A;  3MOW A;  3PS5 A;  4GE6 A;  2A8B A;  1AAX A;  3RGO A;  1WAX A;  3ZMP A;  3D42 A;  3QCJ A;  1KAK A;  2QCJ A;  3S4O A;  2P4D A;  4GS0 A;  1OEV A;  2F6Z A;  2H4V A;  1YZ4 A;  3V0F A;  4GRY A;  2GP0 A;  3I36 A;  2I1Y A;  3RO1 A;  3I80 A;  4YAA A;  3QKP A;  2PSZ A;  1YGU A;  4AZ1 A;  2CNF A;  1ONY A;  4NX8 A;  5KA1 A;  5BX1 A;  2CMB A;  2I42 A;  2I6O A;  2NT7 A;  3QKQ A;  2CNI A;  2HC1 A;  1Q6S A;  5BUG A;  1C83 A; 
#chains in the Genus database with same CATH topology
 3F99 A;  4ERC A;  2QEP A;  4QDI A;  2VEU A;  2I5X A;  5BZZ A;  2VOR A;  1J6U A;  2GWO A;  1YPT A;  3GXG A;  2ZN7 A;  2OC3 A;  1U24 A;  3O4T A;  4BPC A;  1T49 A;  4OHI A;  4ZRT A;  3QCF A;  5M43 A;  4NWF A;  3QCI A;  4JBC A;  4JMK A;  3V0I A;  1FPR A;  2H02 A;  4OHD A;  1G4W R;  1NZ7 A;  2I6J A;  3HN7 A;  3BLU A;  4OHE A;  3QCH A;  4JNB A;  2H4K A;  1C88 A;  1YTS A;  3EB1 A;  4HJP A;  1LQF A;  2H03 A;  5GTJ A;  2I75 A;  4H1O A;  2CM7 A;  3F9A A;  2I4H A;  2OOQ A;  1EEN A;  3S3F A;  4BJO A;  2Y1O A;  4NWG A;  1ONZ A;  1O5Z A;  3S3E A;  4QBW A;  4R0T A;  1L8K A;  1WRM A;  1NWE A;  5KA9 A;  5A5E A;  2SHP A;  5KA0 A;  3UAG A;  2CFV A;  2F46 A;  2GCA A;  2J16 B;  1PA1 A;  2F6Y A;  3SME A;  2AM1 A;  2AHS A;  4RI5 A;  2GJT A;  2VEV A;  1PTY A;  3ZM0 A;  2HB1 A;  2JFF A;  2Y67 A;  3ZM2 A;  3V0G A;  3F41 A;  1A5Y A;  4KYR A;  2XPC A;  2IMG A;  1YTN A;  3U96 A;  4ZN5 A;  5LXQ B;  2QBQ A;  4BUC A;  1XXP A;  3A5J A;  3A5K A;  2CM2 A;  3O5X A;  1X24 A;  3O4U A;  4KI9 A;  5KAA A;  1OEO X;  2CMA A;  2QBS A;  2HNP A;  1JLN A;  2X5O A;  1QXK A;  5KAD A;  1LYV A;  2QDP A;  4PYH A;  1XRI A;  1V3A A;  3CWE A;  3LK7 A;  5KAB A;  2I3R A;  2PA5 A;  5K9V A;  2XJA A;  3NRS A;  2F70 A;  1XM2 A;  1YN9 A;  2CMC A;  4QAH A;  5K25 A;  1JBV A;  5HDE A;  3RZ2 A;  5MMZ B;  3EMU A;  4RH5 A;  3MOZ A;  2B4S A;  3EAX A;  2F6T A;  2MBC A;  4GFV A;  1NNY A;  3D1O A;  3V0J A;  2B4P A;  2RF6 A;  3ZV2 A;  1EEH A;  4J51 A;  4BUB A;  4ZI4 A;  2I4G A;  1R6H A;  2NV5 A;  3QCD A;  4D3R A;  3B7O A;  3BM8 A;  2I6M A;  1PYN A;  4WU3 A;  2AM2 A;  1RXD A;  2VEX A;  4GE2 A;  2F00 A;  3ZM6 A;  1OEU A;  4ICZ A;  2P6X A;  2Y68 A;  5I6V A;  1PXH A;  1G7F A;  1BZC A;  2GCB A;  2VEW A;  3OLR A;  1T48 A;  4GFU A;  2NZ6 A;  1C87 A;  2HNQ A;  2I4E A;  2I3U A;  3BLT A;  3AWF A;  4CVK A;  4WTY A;  2H4G A;  2HXP A;  1PTT A;  5EHR A;  1T4J A;  5KA2 A;  1GFY A;  1FPZ A;  2E0T A;  2PBN A;  3F9B A;  4QUN A;  3OMH A;  4OHL A;  2OUD A;  2NLK A;  2Y96 A;  5KAC A;  2FJN A;  3S3H A;  1XXV A;  5KA4 A;  2J17 A;  2UAG A;  2FH7 A;  1PTV A;  3ZM1 A;  2YDU A;  2CM8 A;  1OEM X;  3N0A A;  3O4S A;  4JMJ A;  1C85 A;  4TVV A;  4D3P A;  4Y2E A;  5KA7 A;  5KA3 A;  2ZMM A;  2CNH A;  4B04 A;  4GE5 A;  4WOH A;  2BGE A;  1PA9 A;  2C46 A;  2F6W A;  4QAP A;  2CJZ A;  3S3K A;  2VTD A;  1MKP A;  4QUM A;  4RI4 A;  1Q6N A;  1PTU A;  3D44 A;  5K24 A;  1W78 A;  5K23 A;  1C84 A;  3D1H A;  4OHH A;  3D9C A;  2ESB A;  3V0E A;  1LAR A;  3V0H A;  1GQQ A;  1ZC0 A;  2G6Z A;  1ZCK A;  3LJ8 A;  1J4X A;  2G59 A;  1JF7 A;  1KAV A;  4YR8 B;  1GWZ A;  1ZZW A;  3QCM A;  2GC5 A;  3QCC A;  2J16 A;  3V0D A;  1OET A;  1WCH A;  1Q6J A;  4CVM A;  1RPM A;  1Q1M A;  2QBR A;  2R0B A;  2I6P A;  3QCL A;  4IKC A;  2QDM A;  3CM3 A;  5AWX A;  3RGQ A;  2JJD A;  2C7S A;  2Q05 A;  2HC2 A;  4NND A;  1JBW A;  2Y66 A;  4RHG A;  1I9S A;  1P3D A;  4C12 A;  1YGR A;  2Q47 A;  1OHE A;  2Y2F A;  3QCB A;  2CNG A;  2QBP A;  3BRH A;  3EU0 A;  5K9W A;  1YTW A;  1U26 A;  2M3V A;  2QCT A;  2F6V A;  1EEO A;  1PH0 A;  1D5R A;  1VHR A;  1G1G A;  2HCM A;  3ZM5 A;  4WU2 A;  2WJP A;  3QCG A;  1Q6P A;  2I6I A;  2H04 A;  1P15 A;  4UAG A;  1BZJ A;  3N2A A;  4HJQ A;  1NWL A;  4D3Q A;  4DGX A;  2UUP A;  3D1Q A;  4R0S A;  1W7K A;  2JFG A;  2GC6 A;  5IBS A;  3QCE A;  3F81 A;  1OHD A;  2WGP A;  5J8R A;  1M3G A;  3MVN A;  4S0G A;  3MMJ A;  2B07 A;  4HRF A;  2VOS A;  2B3O A;  2A3K A;  2VEY A;  3ZL8 A;  3I7Z A;  3QCN A;  2CNE A;  3O3L A;  3QCK A;  2AZR A;  1U25 A;  1G1H A;  2PT0 A;  2NT2 A;  2NTA A;  3ZM3 A;  2FJM A;  2CM3 A;  3QCZ A;  2F71 A;  1OHC A;  5KA8 A;  1I9T A;  2B4O A;  2BV5 A;  4R30 A;  1C86 A;  5EHP A;  3AWE A;  4QF5 A;  2BIJ A;  5A5F A;  2BGD A;  4PVG A;  4CVL A;  3EZZ A;  4H34 A;  2HY3 A;  4GWF A;  1NL9 A;  4QBE A;  4Y14 A;  2WTZ A;  2DXP A;  1YFO A;  4RKK A;  4KYQ A;  2QDC A;  2UUO A;  4MBB A;  3SR9 A;  1Q6M A;  1XBO A;  2BZL A;  4I8N A;  3AWG A;  1L8G A;  5BZX A;  1YWF A;  5IBM A;  2OZ5 A;  1I57 A;  2B4U A;  1G4U S;  1E0D A;  2PI7 A;  1G7G A;  4Z6B A;  1ZCL A;  4C13 A;  1P31 A;  3GXH A;  4GRZ A;  4NYH A;  4HV4 A;  2HVL A;  4DGP A;  1BZH A;  1UAG A;  3ZMQ A;  1Q6T A;  1E8C A;  1G1F A;  2PQ5 A;  1QZ0 A;  3M4U A;  1NO6 A;  3NME A;  3H2X A;  5K22 A;  2B49 A;  1FQ1 A;  3S4E A;  4RDD A;  1OES A;  1SUG A;  2VTE A;  4RH9 A;  1ECV A;  2F6F A;  3MOW A;  3PS5 A;  4GE6 A;  2A8B A;  1GG4 A;  1AAX A;  3RGO A;  1WAX A;  4ZIY A;  3ZMP A;  3D42 A;  3QCJ A;  1KAK A;  1FGS A;  2QCJ A;  3S4O A;  2P4D A;  4GS0 A;  1OEV A;  2F6Z A;  2H4V A;  1YZ4 A;  3V0F A;  4GRY A;  2GP0 A;  3I36 A;  2I1Y A;  3RO1 A;  3I80 A;  4YAA A;  3QKP A;  2PSZ A;  3PYZ A;  1YGU A;  4AZ1 A;  2CNF A;  1ONY A;  4NX8 A;  5KA1 A;  5BX1 A;  2CMB A;  2I42 A;  2I6O A;  2NT7 A;  1GQY A;  3QKQ A;  2CNI A;  2HC1 A;  1Q6S A;  5BUG A;  2JFH A;  1C83 A; 
#chains in the Genus database with same CATH homology
 3F99 A;  4ERC A;  2QEP A;  2VEU A;  2I5X A;  5BZZ A;  2GWO A;  1YPT A;  3GXG A;  2ZN7 A;  2OC3 A;  1U24 A;  3O4T A;  4BPC A;  1T49 A;  4OHI A;  4ZRT A;  3QCF A;  5M43 A;  4NWF A;  3QCI A;  4JBC A;  4JMK A;  3V0I A;  1FPR A;  2H02 A;  4OHD A;  1G4W R;  1NZ7 A;  2I6J A;  3BLU A;  4OHE A;  3QCH A;  4JNB A;  2H4K A;  1C88 A;  1YTS A;  3EB1 A;  4HJP A;  1LQF A;  2H03 A;  5GTJ A;  2I75 A;  4H1O A;  2CM7 A;  3F9A A;  2I4H A;  2OOQ A;  1EEN A;  3S3F A;  4BJO A;  4NWG A;  1ONZ A;  3S3E A;  4QBW A;  4R0T A;  1L8K A;  1WRM A;  1NWE A;  5KA9 A;  2SHP A;  5KA0 A;  2CFV A;  2F46 A;  2J16 B;  1PA1 A;  2F6Y A;  3SME A;  2AHS A;  4RI5 A;  2GJT A;  2VEV A;  1PTY A;  3ZM0 A;  2HB1 A;  3ZM2 A;  3V0G A;  3F41 A;  1A5Y A;  4KYR A;  2IMG A;  1YTN A;  3U96 A;  4ZN5 A;  5LXQ B;  2QBQ A;  1XXP A;  3A5J A;  3A5K A;  2CM2 A;  3O5X A;  1X24 A;  3O4U A;  4KI9 A;  5KAA A;  1OEO X;  2CMA A;  2QBS A;  2HNP A;  1JLN A;  5KAD A;  1QXK A;  1LYV A;  2QDP A;  4PYH A;  1XRI A;  1V3A A;  3CWE A;  5KAB A;  2I3R A;  2PA5 A;  5K9V A;  2F70 A;  1XM2 A;  1YN9 A;  2CMC A;  4QAH A;  5K25 A;  5HDE A;  3RZ2 A;  5MMZ B;  3EMU A;  4RH5 A;  3MOZ A;  2B4S A;  3EAX A;  2F6T A;  2MBC A;  4GFV A;  1NNY A;  3D1O A;  3V0J A;  2B4P A;  2RF6 A;  3ZV2 A;  4J51 A;  4ZI4 A;  2I4G A;  1R6H A;  2NV5 A;  3QCD A;  4D3R A;  3B7O A;  3BM8 A;  2I6M A;  1PYN A;  4WU3 A;  1RXD A;  2VEX A;  4GE2 A;  1OEU A;  4ICZ A;  2P6X A;  5I6V A;  1PXH A;  1G7F A;  1BZC A;  2VEW A;  3OLR A;  1T48 A;  4GFU A;  2NZ6 A;  1C87 A;  2HNQ A;  2I4E A;  2I3U A;  3BLT A;  3AWF A;  4WTY A;  2H4G A;  2HXP A;  1PTT A;  5EHR A;  1T4J A;  5KA2 A;  1GFY A;  1FPZ A;  2E0T A;  2PBN A;  3F9B A;  4QUN A;  3OMH A;  4OHL A;  2OUD A;  2NLK A;  2Y96 A;  5KAC A;  2FJN A;  3S3H A;  1XXV A;  5KA4 A;  2J17 A;  2FH7 A;  1PTV A;  3ZM1 A;  2YDU A;  2CM8 A;  1OEM X;  3N0A A;  3O4S A;  4JMJ A;  1C85 A;  4TVV A;  4D3P A;  4Y2E A;  5KA7 A;  5KA3 A;  2ZMM A;  2CNH A;  4B04 A;  4GE5 A;  4WOH A;  2BGE A;  1PA9 A;  2C46 A;  2F6W A;  4QAP A;  2CJZ A;  3S3K A;  1MKP A;  4QUM A;  4RI4 A;  1Q6N A;  1PTU A;  3D44 A;  5K24 A;  5K23 A;  1C84 A;  3D1H A;  4OHH A;  3D9C A;  2ESB A;  3V0E A;  1LAR A;  3V0H A;  1ZC0 A;  2G6Z A;  1ZCK A;  3LJ8 A;  1J4X A;  2G59 A;  1JF7 A;  1KAV A;  4YR8 B;  1GWZ A;  1ZZW A;  3QCM A;  3QCC A;  2J16 A;  3V0D A;  1OET A;  1WCH A;  1Q6J A;  1RPM A;  1Q1M A;  2QBR A;  2R0B A;  2I6P A;  3QCL A;  4IKC A;  2QDM A;  3CM3 A;  5AWX A;  3RGQ A;  2JJD A;  2C7S A;  2Q05 A;  2HC2 A;  4NND A;  4RHG A;  1I9S A;  1YGR A;  2Q47 A;  1OHE A;  2Y2F A;  3QCB A;  2CNG A;  2QBP A;  3BRH A;  3EU0 A;  5K9W A;  1YTW A;  1U26 A;  2M3V A;  2QCT A;  2F6V A;  1EEO A;  1PH0 A;  1D5R A;  1VHR A;  1G1G A;  2HCM A;  4WU2 A;  3QCG A;  1Q6P A;  2I6I A;  2H04 A;  1P15 A;  1BZJ A;  4HJQ A;  1NWL A;  4D3Q A;  4DGX A;  3D1Q A;  4R0S A;  5IBS A;  3QCE A;  3F81 A;  1OHD A;  2WGP A;  5J8R A;  1M3G A;  4S0G A;  3MMJ A;  2B07 A;  4HRF A;  2B3O A;  2A3K A;  2VEY A;  3I7Z A;  3QCN A;  2CNE A;  3O3L A;  3QCK A;  2AZR A;  1U25 A;  1G1H A;  2PT0 A;  2NT2 A;  2NTA A;  3ZM3 A;  2FJM A;  2CM3 A;  2F71 A;  1OHC A;  5KA8 A;  1I9T A;  2B4O A;  2BV5 A;  4R30 A;  1C86 A;  5EHP A;  3AWE A;  2BIJ A;  2BGD A;  4PVG A;  3EZZ A;  4H34 A;  2HY3 A;  4GWF A;  1NL9 A;  4QBE A;  4Y14 A;  2DXP A;  1YFO A;  4RKK A;  4KYQ A;  2QDC A;  4MBB A;  3SR9 A;  1Q6M A;  1XBO A;  2BZL A;  4I8N A;  3AWG A;  1L8G A;  5BZX A;  1YWF A;  5IBM A;  2OZ5 A;  1I57 A;  2B4U A;  1G4U S;  2PI7 A;  1G7G A;  4Z6B A;  1ZCL A;  3GXH A;  4GRZ A;  4NYH A;  2HVL A;  4DGP A;  1BZH A;  3ZMQ A;  1Q6T A;  1G1F A;  2PQ5 A;  1QZ0 A;  3M4U A;  1NO6 A;  3NME A;  3H2X A;  5K22 A;  2B49 A;  1FQ1 A;  3S4E A;  4RDD A;  1OES A;  1SUG A;  4RH9 A;  1ECV A;  2F6F A;  3MOW A;  3PS5 A;  4GE6 A;  2A8B A;  1AAX A;  3RGO A;  1WAX A;  3ZMP A;  3D42 A;  3QCJ A;  1KAK A;  2QCJ A;  3S4O A;  2P4D A;  4GS0 A;  1OEV A;  2F6Z A;  2H4V A;  1YZ4 A;  3V0F A;  4GRY A;  2GP0 A;  3I36 A;  2I1Y A;  3RO1 A;  3I80 A;  4YAA A;  3QKP A;  2PSZ A;  1YGU A;  4AZ1 A;  2CNF A;  1ONY A;  4NX8 A;  5KA1 A;  5BX1 A;  2CMB A;  2I42 A;  2I6O A;  2NT7 A;  3QKQ A;  2CNI A;  2HC1 A;  1Q6S A;  5BUG A;  1C83 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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