1KAVA

Human tyrosine phosphatase 1b complexed with an inhibitor
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
total genus 106
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2001-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1kavA00
2IMGA 3S4EA 2QCJA 1XRIA 2J16B 1Q6PA 2F6TA 1NZ7A 5KA7A 2QBRA 1KAVA 5KA9A 1ONZA 3O4SA 4PVGA 3V0IA 3I80A 1XBOA 5HDEA 1L8KA 1Q6MA 1R6HA 2B07A 1PTUA 4H1OA 4WOHA 1FQ1A 4R30A 4PYHA 2HY3A 2OUDA 1T49A 1FPRA 2H4GA 1OHCA 2ZMMA 1Q1MA 2G6ZA 3QCHA 2PBNA 2SHPA 4KYQA 3ZV2A 2BZLA 2HB1A 2QCTA 3O3LA 2F6YA 2I6JA 4R0TA 1I57A 5KA2A 5K23A 3CWEA 2PQ5A 3ZM2A 4Z6BA 1M3GA 3ZM0A 1NNYA 3SR9A 2HXPA 2CNHA 4S0GA 1OHEA 3BLUA 3QCFA 1PH0A 2QEPA 2VEVA 3V0HA 4GRYA 3F81A 4JNBA 3BRHA 2A3KA 3QCCA 2HCMA 2Y96A 2JJDA 5GTJA 1XM2A 5KA8A 2VEWA 1ZC0A 1LARA 3OMHA 1YTNA 2I1YA 2OZ5A 4KI9A 4GRZA 3V0EA 2I6IA 3RGOA 4Y2EA 1C83A 2BV5A 2J16A 4RI5A 1C88A 5LXQB 2ZN7A 3QCBA 4QUNA 5M43A 4J51A 2CM8A 2I75A 3ZM3A 2QBPA 4JMKA 3CM3A 3N0AA 3QCLA 2H4VA 2F70A 4WU3A 2P4DA 2MBCA 3QKQA 4D3PA 3PS5A 1ZZWA 1G1GA 2H4KA 3EAXA 3V0JA 2FJMA 4WTYA 1T4JA 4OHHA 3QCKA 2QDCA 3NMEA 3O4TA 5KABA 3GXGA 1YGRA 1Q6TA 1XXVA 3SMEA 1G4US 1I9SA 3QKPA 2WGPA 1C87A 3D44A 2F6FA 2I4EA 2ESBA 4HJQA 2CNEA 2PT0A 2QBQA 2CM2A 3V0FA 1WCHA 1OEOX 2RF6A 3S3FA 4ZRTA 2NTAA 3B7OA 4JBCA 4NWFA 2CJZA 1YPTA 5KADA 1YTWA 2BGDA 2I6MA 4NYHA 2I4HA 1U24A 5K9VA 3AWGA 2CMAA 1VHRA 3V0GA 2NLKA 1GFYA 2VEUA 2CMBA 4JMJA 3ZM1A 2QBSA 4B04A 1YGUA 4YR8B 4HRFA 1MKPA 3O4UA 1YFOA 2HC2A 4I8NA 1C86A 1QZ0A 3AWFA 3S3HA 1GWZA 1NO6A 3OLRA 5KAAA 3RO1A 2H03A 2AZRA 1OETA 2R0BA 3QCMA 4BPCA 1XXPA 2CNGA 3QCJA 1PTTA 1ONYA 2CFVA 4OHLA 3A5JA 1KAKA 1Q6SA 2PSZA 3S3KA 4ERCA 2P6XA 1JF7A 3D1QA 1AAXA 2C46A 3A5KA 3EU0A 2HNQA 3D9CA 1RPMA 1G1HA 5KACA 5EHPA 4QAPA 1NL9A 1OHDA 2I6PA 4GWFA 4GFUA 5IBSA 3I7ZA 4NWGA 1LYVA 1PA1A 1FPZA 2B4SA 3O5XA 1EENA 1QXKA 1YN9A 3MMJA 3ZMPA 1WAXA 2FH7A 2CM3A 4RDDA 2YDUA 1BZJA 2F6ZA 1A5YA 2PA5A 3F99A 3QCGA 2B4PA 1Q6JA 3EZZA 5KA3A 2VEXA 4ZI4A 2C7SA 5KA4A 2F6WA 1JLNA 1T48A 4RH5A 2Q47A 4ZN5A 3U96A 4QBWA 4NX8A 3EMUA 1J4XA 1PYNA 2NV5A 2B3OA 5K9WA 2FJNA 3S4OA 2NT7A 1OEMX 1D5RA 3RZ2A 1U26A 1ZCLA 2I4GA 2NT2A 3F9BA 3QCDA 3F9AA 4RH9A 2HVLA 1LQFA 4RKKA 2QDPA 3V0DA 2F6VA 5AWXA 2I42A 3D42A 5J8RA 3BM8A 3H2XA 5KA1A 2Q05A 4H34A 2I6OA 1EEOA 2OOQA 2GJTA 2I3UA 4GE2A 1ZCKA 2H02A 3AWEA 1NWEA 2CM7A 2F71A 1NWLA 1Q6NA 5BZXA 3QCNA 2A8BA 2GWOA 3M4UA 2G59A 2B49A 3EB1A 1BZCA 1OESA 5MMZB 1G1FA 4GE6A 4AZ1A 1YWFA 2AHSA 4R0SA 1PA9A 4GE5A 2B4UA 1U25A 3D1HA 2PI7A 3S3EA 1I9TA 2H04A 3QCEA 4HJPA 1P15A 4D3RA 2F46A 4YAAA 2OC3A 2BIJA 2HNPA 4NNDA 3MOZA 2Y2FA 2DXPA 4BJOA 1WRMA 3QCIA 1SUGA 4QAHA 4Y14A 1PTYA 4D3QA 1X24A 5K25A 4QUMA 3BLTA 2BGEA 5BZZA 4GFVA 4QBEA 4TVVA 4MBBA 2M3VA 2VEYA 4RHGA 1G7FA 1V3AA 3GXHA 1OEVA 3D1OA 4DGPA 5BX1A 4GS0A 3ZMQA 5EHRA 5K22A 5K24A 1OEUA 4ICZA 4OHIA 3RGQA 2NZ6A 5IBMA 1RXDA 2GP0A 2I5XA 1BZHA 1C85A 4OHEA 5BUGA 1C84A 4WU2A 1PXHA 4DGXA 4KYRA 2CNIA 3I36A 4RI4A 2CMCA 2HC1A 1L8GA 1YTSA 2E0TA 1YZ4A 2B4OA 2I3RA 2QDMA 2CNFA 1G7GA 5I6VA 1G4WR 2J17A 3F41A 5KA0A 3LJ8A 4IKCA 3MOWA 1ECVA 1PTVA 4OHDA
chains in the Genus database with same CATH superfamily
2IMGA 3S4EA 2QCJA 1XRIA 2J16B 1Q6PA 2F6TA 3LK7A 1NZ7A 5KA7A 2QBRA 1KAVA 2VTDA 5KA9A 2GCBA 1ONZA 1GG4A 3O4SA 4PVGA 3V0IA 3I80A 1XBOA 5HDEA 1L8KA 1Q6MA 1R6HA 2B07A 2GC6A 1PTUA 4H1OA 4WOHA 1FQ1A 4R30A 4PYHA 2HY3A 2OUDA 1T49A 1FPRA 2H4GA 2Y67A 1OHCA 1GQYA 2ZMMA 1Q1MA 2G6ZA 3QCHA 2PBNA 2SHPA 4KYQA 3ZV2A 2BZLA 2HB1A 2QCTA 3O3LA 2F6YA 2I6JA 4R0TA 1I57A 5KA2A 5K23A 3CWEA 2PQ5A 3ZM2A 4Z6BA 1M3GA 3ZM0A 1NNYA 3SR9A 4BUCA 2HXPA 4C13A 2CNHA 2X5OA 2GC5A 4S0GA 1OHEA 2Y68A 3BLUA 3QCFA 1PH0A 2QEPA 2VEVA 3V0HA 4GRYA 3F81A 4JNBA 3BRHA 3ZL8A 3ZM6A 2A3KA 3QCCA 2HCMA 2Y96A 2JJDA 5GTJA 1XM2A 5KA8A 2VEWA 1ZC0A 1LARA 3OMHA 1YTNA 2I1YA 2OZ5A 2UUPA 4KI9A 4GRZA 3V0EA 2I6IA 3RGOA 4Y2EA 4UAGA 1C83A 2BV5A 2J16A 2VTEA 4RI5A 1C88A 5LXQB 2ZN7A 3QCBA 4QUNA 5M43A 4J51A 2CM8A 1P3DA 2I75A 3ZM3A 2QBPA 4JMKA 3CM3A 3N0AA 3QCLA 2H4VA 2F70A 4WU3A 4HV4A 2P4DA 2MBCA 3QKQA 4D3PA 3PS5A 1ZZWA 1G1GA 2H4KA 3EAXA 3V0JA 2FJMA 4WTYA 1T4JA 4OHHA 1JBVA 3QCKA 2QDCA 3NMEA 2WTZA 3O4TA 5KABA 3GXGA 1YGRA 1Q6TA 2AM2A 1XXVA 2JFFA 3SMEA 1G4US 3HN7A 1I9SA 3QKPA 2WGPA 1UAGA 2JFHA 1C87A 3D44A 2F6FA 2I4EA 2ESBA 4HJQA 2CNEA 2PT0A 2QBQA 2CM2A 2VOSA 3V0FA 1WCHA 1OEOX 2RF6A 3S3FA 4ZRTA 2NTAA 3B7OA 4JBCA 4NWFA 2CJZA 2UAGA 1YPTA 5KADA 1YTWA 1W7KA 2BGDA 2I6MA 1E0DA 4NYHA 2I4HA 1U24A 5K9VA 3AWGA 2CMAA 1VHRA 3V0GA 3UAGA 2NLKA 1GFYA 2VEUA 2CMBA 4JMJA 3ZM1A 2QBSA 4B04A 1YGUA 3QCZA 4HRFA 4YR8B 1MKPA 3O4UA 1YFOA 2HC2A 4I8NA 1C86A 1QZ0A 3AWFA 3S3HA 1GWZA 1NO6A 3OLRA 5KAAA 3RO1A 2H03A 2AZRA 1OETA 2R0BA 3QCMA 4BPCA 1XXPA 2CNGA 3QCJA 1PTTA 1ONYA 2CFVA 4OHLA 4CVMA 3A5JA 1KAKA 1Q6SA 2Y66A 2PSZA 3S3KA 4ERCA 2P6XA 1J6UA 1JF7A 3D1QA 1AAXA 2C46A 3A5KA 3EU0A 2HNQA 5A5EA 3D9CA 1RPMA 1G1HA 4QDIA 5KACA 5EHPA 4QAPA 1NL9A 1OHDA 2I6PA 4GWFA 4GFUA 5IBSA 3I7ZA 4NWGA 1LYVA 1PA1A 1FPZA 2B4SA 3O5XA 1EENA 3MVNA 1QXKA 2JFGA 1YN9A 1E8CA 3MMJA 3ZMPA 1WAXA 2FH7A 2CM3A 4RDDA 2YDUA 2VORA 1BZJA 2F6ZA 1A5YA 2PA5A 3F99A 3QCGA 2B4PA 1Q6JA 3EZZA 5KA3A 2UUOA 2VEXA 4ZI4A 2C7SA 5KA4A 4ZIYA 2F6WA 1JLNA 1T48A 4RH5A 2Q47A 4ZN5A 3U96A 4QBWA 2GCAA 4NX8A 3EMUA 1J4XA 4QF5A 1PYNA 2NV5A 2B3OA 1W78A 5K9WA 2FJNA 2XJAA 3S4OA 2NT7A 1OEMX 1D5RA 3RZ2A 2WJPA 3NRSA 1U26A 1ZCLA 2I4GA 2NT2A 3F9BA 3QCDA 3F9AA 4RH9A 2HVLA 1LQFA 4RKKA 2QDPA 3V0DA 2F6VA 5AWXA 2I42A 1O5ZA 3D42A 5J8RA 1P31A 3BM8A 3H2XA 5KA1A 2F00A 2Q05A 4H34A 2I6OA 1EEOA 2OOQA 2GJTA 2I3UA 4GE2A 1ZCKA 2H02A 3AWEA 1NWEA 2CM7A 2F71A 1NWLA 1Q6NA 4C12A 5BZXA 3QCNA 2A8BA 3ZM5A 2GWOA 3M4UA 2G59A 2B49A 3EB1A 1BZCA 1OESA 5MMZB 1G1FA 5A5FA 4GE6A 4AZ1A 1YWFA 2AHSA 4R0SA 1EEHA 1PA9A 4GE5A 2B4UA 1U25A 3D1HA 2PI7A 3S3EA 1I9TA 2H04A 3QCEA 4HJPA 1P15A 4D3RA 2F46A 1FGSA 2OC3A 4YAAA 2BIJA 2HNPA 4NNDA 3MOZA 2Y2FA 2DXPA 4BJOA 1WRMA 3QCIA 1SUGA 4QAHA 4CVLA 4Y14A 1PTYA 4D3QA 1X24A 5K25A 4QUMA 3BLTA 2BGEA 5BZZA 4GFVA 4QBEA 1JBWA 4TVVA 4MBBA 2M3VA 2VEYA 4RHGA 1G7FA 1V3AA 3GXHA 1OEVA 3D1OA 4DGPA 5BX1A 4GS0A 3ZMQA 1GQQA 5EHRA 5K22A 5K24A 1OEUA 4ICZA 4OHIA 3RGQA 2NZ6A 2Y1OA 5IBMA 2AM1A 1RXDA 2GP0A 2I5XA 1BZHA 1C85A 4OHEA 5BUGA 1C84A 4WU2A 1PXHA 4DGXA 4KYRA 3PYZA 2CNIA 3I36A 4BUBA 4RI4A 2CMCA 2HC1A 1L8GA 4CVKA 1YTSA 2E0TA 1YZ4A 2B4OA 2I3RA 2QDMA 2CNFA 1G7GA 5I6VA 1G4WR 2J17A 3F41A 5KA0A 2XPCA 3LJ8A 4IKCA 3MOWA 1ECVA 3N2AA 1PTVA 4OHDA
chains in the Genus database with same CATH topology
2IMGA 3S4EA 2QCJA 1XRIA 2J16B 1Q6PA 2F6TA 1NZ7A 5KA7A 2QBRA 1KAVA 5KA9A 1ONZA 3O4SA 4PVGA 3V0IA 3I80A 1XBOA 5HDEA 1L8KA 1Q6MA 1R6HA 2B07A 1PTUA 4H1OA 4WOHA 1FQ1A 4R30A 4PYHA 2HY3A 2OUDA 1T49A 1FPRA 2H4GA 1OHCA 2ZMMA 1Q1MA 2G6ZA 3QCHA 2PBNA 2SHPA 4KYQA 3ZV2A 2BZLA 2HB1A 2QCTA 3O3LA 2F6YA 2I6JA 4R0TA 1I57A 5KA2A 5K23A 3CWEA 2PQ5A 3ZM2A 4Z6BA 1M3GA 3ZM0A 1NNYA 3SR9A 2HXPA 2CNHA 4S0GA 1OHEA 3BLUA 3QCFA 1PH0A 2QEPA 2VEVA 3V0HA 4GRYA 3F81A 4JNBA 3BRHA 2A3KA 3QCCA 2HCMA 2Y96A 2JJDA 5GTJA 1XM2A 5KA8A 2VEWA 1ZC0A 1LARA 3OMHA 1YTNA 2I1YA 2OZ5A 4KI9A 4GRZA 3V0EA 2I6IA 3RGOA 4Y2EA 1C83A 2BV5A 2J16A 4RI5A 1C88A 5LXQB 2ZN7A 3QCBA 4QUNA 5M43A 4J51A 2CM8A 2I75A 3ZM3A 2QBPA 4JMKA 3CM3A 3N0AA 3QCLA 2H4VA 2F70A 4WU3A 2P4DA 2MBCA 3QKQA 4D3PA 3PS5A 1ZZWA 1G1GA 2H4KA 3EAXA 3V0JA 2FJMA 4WTYA 1T4JA 4OHHA 3QCKA 2QDCA 3NMEA 3O4TA 5KABA 3GXGA 1YGRA 1Q6TA 1XXVA 3SMEA 1G4US 1I9SA 3QKPA 2WGPA 1C87A 3D44A 2F6FA 2I4EA 2ESBA 4HJQA 2CNEA 2PT0A 2QBQA 2CM2A 3V0FA 1WCHA 1OEOX 2RF6A 3S3FA 4ZRTA 2NTAA 3B7OA 4JBCA 4NWFA 2CJZA 1YPTA 5KADA 1YTWA 2BGDA 2I6MA 4NYHA 2I4HA 1U24A 5K9VA 3AWGA 2CMAA 1VHRA 3V0GA 2NLKA 1GFYA 2VEUA 2CMBA 4JMJA 3ZM1A 2QBSA 4B04A 1YGUA 4YR8B 4HRFA 1MKPA 3O4UA 1YFOA 2HC2A 4I8NA 1C86A 1QZ0A 3AWFA 3S3HA 1GWZA 1NO6A 3OLRA 5KAAA 3RO1A 2H03A 2AZRA 1OETA 2R0BA 3QCMA 4BPCA 1XXPA 2CNGA 3QCJA 1PTTA 1ONYA 2CFVA 4OHLA 3A5JA 1KAKA 1Q6SA 2PSZA 3S3KA 4ERCA 2P6XA 1JF7A 3D1QA 1AAXA 2C46A 3A5KA 3EU0A 2HNQA 3D9CA 1RPMA 1G1HA 5KACA 5EHPA 4QAPA 1NL9A 1OHDA 2I6PA 4GWFA 4GFUA 5IBSA 3I7ZA 4NWGA 1LYVA 1PA1A 1FPZA 2B4SA 3O5XA 1EENA 1QXKA 1YN9A 3MMJA 3ZMPA 1WAXA 2FH7A 2CM3A 4RDDA 2YDUA 1BZJA 2F6ZA 1A5YA 2PA5A 3F99A 3QCGA 2B4PA 1Q6JA 3EZZA 5KA3A 2VEXA 4ZI4A 2C7SA 5KA4A 2F6WA 1JLNA 1T48A 4RH5A 2Q47A 4ZN5A 3U96A 4QBWA 4NX8A 3EMUA 1J4XA 1PYNA 2NV5A 2B3OA 5K9WA 2FJNA 3S4OA 2NT7A 1OEMX 1D5RA 3RZ2A 1U26A 1ZCLA 2I4GA 2NT2A 3F9BA 3QCDA 3F9AA 4RH9A 2HVLA 1LQFA 4RKKA 2QDPA 3V0DA 2F6VA 5AWXA 2I42A 3D42A 5J8RA 3BM8A 3H2XA 5KA1A 2Q05A 4H34A 2I6OA 1EEOA 2OOQA 2GJTA 2I3UA 4GE2A 1ZCKA 2H02A 3AWEA 1NWEA 2CM7A 2F71A 1NWLA 1Q6NA 5BZXA 3QCNA 2A8BA 2GWOA 3M4UA 2G59A 2B49A 3EB1A 1BZCA 1OESA 5MMZB 1G1FA 4GE6A 4AZ1A 1YWFA 2AHSA 4R0SA 1PA9A 4GE5A 2B4UA 1U25A 3D1HA 2PI7A 3S3EA 1I9TA 2H04A 3QCEA 4HJPA 1P15A 4D3RA 2F46A 4YAAA 2OC3A 2BIJA 2HNPA 4NNDA 3MOZA 2Y2FA 2DXPA 4BJOA 1WRMA 3QCIA 1SUGA 4QAHA 4Y14A 1PTYA 4D3QA 1X24A 5K25A 4QUMA 3BLTA 2BGEA 5BZZA 4GFVA 4QBEA 4TVVA 4MBBA 2M3VA 2VEYA 4RHGA 1G7FA 1V3AA 3GXHA 1OEVA 3D1OA 4DGPA 5BX1A 4GS0A 3ZMQA 5EHRA 5K22A 5K24A 1OEUA 4ICZA 4OHIA 3RGQA 2NZ6A 5IBMA 1RXDA 2GP0A 2I5XA 1BZHA 1C85A 4OHEA 5BUGA 1C84A 4WU2A 1PXHA 4DGXA 4KYRA 2CNIA 3I36A 4RI4A 2CMCA 2HC1A 1L8GA 1YTSA 2E0TA 1YZ4A 2B4OA 2I3RA 2QDMA 2CNFA 1G7GA 5I6VA 1G4WR 2J17A 3F41A 5KA0A 3LJ8A 4IKCA 3MOWA 1ECVA 1PTVA 4OHDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IMG A;  3S4E A;  2QCJ A;  1XRI A;  2J16 B;  1Q6P A;  2F6T A;  1NZ7 A;  5KA7 A;  2QBR A;  1KAV A;  5KA9 A;  1ONZ A;  3O4S A;  4PVG A;  3V0I A;  3I80 A;  1XBO A;  5HDE A;  1L8K A;  1Q6M A;  1R6H A;  2B07 A;  1PTU A;  4H1O A;  4WOH A;  1FQ1 A;  4R30 A;  4PYH A;  2HY3 A;  2OUD A;  1T49 A;  1FPR A;  2H4G A;  1OHC A;  2ZMM A;  1Q1M A;  2G6Z A;  3QCH A;  2PBN A;  2SHP A;  4KYQ A;  3ZV2 A;  2BZL A;  2HB1 A;  2QCT A;  3O3L A;  2F6Y A;  2I6J A;  4R0T A;  1I57 A;  5KA2 A;  5K23 A;  3CWE A;  2PQ5 A;  3ZM2 A;  4Z6B A;  1M3G A;  3ZM0 A;  1NNY A;  3SR9 A;  2HXP A;  2CNH A;  4S0G A;  1OHE A;  3BLU A;  3QCF A;  1PH0 A;  2QEP A;  2VEV A;  3V0H A;  4GRY A;  3F81 A;  4JNB A;  3BRH A;  2A3K A;  3QCC A;  2HCM A;  2Y96 A;  2JJD A;  5GTJ A;  1XM2 A;  5KA8 A;  2VEW A;  1ZC0 A;  1LAR A;  3OMH A;  1YTN A;  2I1Y A;  2OZ5 A;  4KI9 A;  4GRZ A;  3V0E A;  2I6I A;  3RGO A;  4Y2E A;  1C83 A;  2BV5 A;  2J16 A;  4RI5 A;  1C88 A;  5LXQ B;  2ZN7 A;  3QCB A;  4QUN A;  5M43 A;  4J51 A;  2CM8 A;  2I75 A;  3ZM3 A;  2QBP A;  4JMK A;  3CM3 A;  3N0A A;  3QCL A;  2H4V A;  2F70 A;  4WU3 A;  2P4D A;  2MBC A;  3QKQ A;  4D3P A;  3PS5 A;  1ZZW A;  1G1G A;  2H4K A;  3EAX A;  3V0J A;  2FJM A;  4WTY A;  1T4J A;  4OHH A;  3QCK A;  2QDC A;  3NME A;  3O4T A;  5KAB A;  3GXG A;  1YGR A;  1Q6T A;  1XXV A;  3SME A;  1G4U S;  1I9S A;  3QKP A;  2WGP A;  1C87 A;  3D44 A;  2F6F A;  2I4E A;  2ESB A;  4HJQ A;  2CNE A;  2PT0 A;  2QBQ A;  2CM2 A;  3V0F A;  1WCH A;  1OEO X;  2RF6 A;  3S3F A;  4ZRT A;  2NTA A;  3B7O A;  4JBC A;  4NWF A;  2CJZ A;  1YPT A;  5KAD A;  1YTW A;  2BGD A;  2I6M A;  4NYH A;  2I4H A;  1U24 A;  5K9V A;  3AWG A;  2CMA A;  1VHR A;  3V0G A;  2NLK A;  1GFY A;  2VEU A;  2CMB A;  4JMJ A;  3ZM1 A;  2QBS A;  4B04 A;  1YGU A;  4YR8 B;  4HRF A;  1MKP A;  3O4U A;  1YFO A;  2HC2 A;  4I8N A;  1C86 A;  1QZ0 A;  3AWF A;  3S3H A;  1GWZ A;  1NO6 A;  3OLR A;  5KAA A;  3RO1 A;  2H03 A;  2AZR A;  1OET A;  2R0B A;  3QCM A;  4BPC A;  1XXP A;  2CNG A;  3QCJ A;  1PTT A;  1ONY A;  2CFV A;  4OHL A;  3A5J A;  1KAK A;  1Q6S A;  2PSZ A;  3S3K A;  4ERC A;  2P6X A;  1JF7 A;  3D1Q A;  1AAX A;  2C46 A;  3A5K A;  3EU0 A;  2HNQ A;  3D9C A;  1RPM A;  1G1H A;  5KAC A;  5EHP A;  4QAP A;  1NL9 A;  1OHD A;  2I6P A;  4GWF A;  4GFU A;  5IBS A;  3I7Z A;  4NWG A;  1LYV A;  1PA1 A;  1FPZ A;  2B4S A;  3O5X A;  1EEN A;  1QXK A;  1YN9 A;  3MMJ A;  3ZMP A;  1WAX A;  2FH7 A;  2CM3 A;  4RDD A;  2YDU A;  1BZJ A;  2F6Z A;  1A5Y A;  2PA5 A;  3F99 A;  3QCG A;  2B4P A;  1Q6J A;  3EZZ A;  5KA3 A;  2VEX A;  4ZI4 A;  2C7S A;  5KA4 A;  2F6W A;  1JLN A;  1T48 A;  4RH5 A;  2Q47 A;  4ZN5 A;  3U96 A;  4QBW A;  4NX8 A;  3EMU A;  1J4X A;  1PYN A;  2NV5 A;  2B3O A;  5K9W A;  2FJN A;  3S4O A;  2NT7 A;  1OEM X;  1D5R A;  3RZ2 A;  1U26 A;  1ZCL A;  2I4G A;  2NT2 A;  3F9B A;  3QCD A;  3F9A A;  4RH9 A;  2HVL A;  1LQF A;  4RKK A;  2QDP A;  3V0D A;  2F6V A;  5AWX A;  2I42 A;  3D42 A;  5J8R A;  3BM8 A;  3H2X A;  5KA1 A;  2Q05 A;  4H34 A;  2I6O A;  1EEO A;  2OOQ A;  2GJT A;  2I3U A;  4GE2 A;  1ZCK A;  2H02 A;  3AWE A;  1NWE A;  2CM7 A;  2F71 A;  1NWL A;  1Q6N A;  5BZX A;  3QCN A;  2A8B A;  2GWO A;  3M4U A;  2G59 A;  2B49 A;  3EB1 A;  1BZC A;  1OES A;  5MMZ B;  1G1F A;  4GE6 A;  4AZ1 A;  1YWF A;  2AHS A;  4R0S A;  1PA9 A;  4GE5 A;  2B4U A;  1U25 A;  3D1H A;  2PI7 A;  3S3E A;  1I9T A;  2H04 A;  3QCE A;  4HJP A;  1P15 A;  4D3R A;  2F46 A;  4YAA A;  2OC3 A;  2BIJ A;  2HNP A;  4NND A;  3MOZ A;  2Y2F A;  2DXP A;  4BJO A;  1WRM A;  3QCI A;  1SUG A;  4QAH A;  4Y14 A;  1PTY A;  4D3Q A;  1X24 A;  5K25 A;  4QUM A;  3BLT A;  2BGE A;  5BZZ A;  4GFV A;  4QBE A;  4TVV A;  4MBB A;  2M3V A;  2VEY A;  4RHG A;  1G7F A;  1V3A A;  3GXH A;  1OEV A;  3D1O A;  4DGP A;  5BX1 A;  4GS0 A;  3ZMQ A;  5EHR A;  5K22 A;  5K24 A;  1OEU A;  4ICZ A;  4OHI A;  3RGQ A;  2NZ6 A;  5IBM A;  1RXD A;  2GP0 A;  2I5X A;  1BZH A;  1C85 A;  4OHE A;  5BUG A;  1C84 A;  4WU2 A;  1PXH A;  4DGX A;  4KYR A;  2CNI A;  3I36 A;  4RI4 A;  2CMC A;  2HC1 A;  1L8G A;  1YTS A;  2E0T A;  1YZ4 A;  2B4O A;  2I3R A;  2QDM A;  2CNF A;  1G7G A;  5I6V A;  1G4W R;  2J17 A;  3F41 A;  5KA0 A;  3LJ8 A;  4IKC A;  3MOW A;  1ECV A;  1PTV A;  4OHD A; 
#chains in the Genus database with same CATH topology
 2IMG A;  3S4E A;  2QCJ A;  1XRI A;  2J16 B;  1Q6P A;  2F6T A;  3LK7 A;  1NZ7 A;  5KA7 A;  2QBR A;  1KAV A;  2VTD A;  5KA9 A;  2GCB A;  1ONZ A;  1GG4 A;  3O4S A;  4PVG A;  3V0I A;  3I80 A;  1XBO A;  5HDE A;  1L8K A;  1Q6M A;  1R6H A;  2B07 A;  2GC6 A;  1PTU A;  4H1O A;  4WOH A;  1FQ1 A;  4R30 A;  4PYH A;  2HY3 A;  2OUD A;  1T49 A;  1FPR A;  2H4G A;  2Y67 A;  1OHC A;  1GQY A;  2ZMM A;  1Q1M A;  2G6Z A;  3QCH A;  2PBN A;  2SHP A;  4KYQ A;  3ZV2 A;  2BZL A;  2HB1 A;  2QCT A;  3O3L A;  2F6Y A;  2I6J A;  4R0T A;  1I57 A;  5KA2 A;  5K23 A;  3CWE A;  2PQ5 A;  3ZM2 A;  4Z6B A;  1M3G A;  3ZM0 A;  1NNY A;  3SR9 A;  4BUC A;  2HXP A;  4C13 A;  2CNH A;  2X5O A;  2GC5 A;  4S0G A;  1OHE A;  2Y68 A;  3BLU A;  3QCF A;  1PH0 A;  2QEP A;  2VEV A;  3V0H A;  4GRY A;  3F81 A;  4JNB A;  3BRH A;  3ZL8 A;  3ZM6 A;  2A3K A;  3QCC A;  2HCM A;  2Y96 A;  2JJD A;  5GTJ A;  1XM2 A;  5KA8 A;  2VEW A;  1ZC0 A;  1LAR A;  3OMH A;  1YTN A;  2I1Y A;  2OZ5 A;  2UUP A;  4KI9 A;  4GRZ A;  3V0E A;  2I6I A;  3RGO A;  4Y2E A;  4UAG A;  1C83 A;  2BV5 A;  2J16 A;  2VTE A;  4RI5 A;  1C88 A;  5LXQ B;  2ZN7 A;  3QCB A;  4QUN A;  5M43 A;  4J51 A;  2CM8 A;  1P3D A;  2I75 A;  3ZM3 A;  2QBP A;  4JMK A;  3CM3 A;  3N0A A;  3QCL A;  2H4V A;  2F70 A;  4WU3 A;  4HV4 A;  2P4D A;  2MBC A;  3QKQ A;  4D3P A;  3PS5 A;  1ZZW A;  1G1G A;  2H4K A;  3EAX A;  3V0J A;  2FJM A;  4WTY A;  1T4J A;  4OHH A;  1JBV A;  3QCK A;  2QDC A;  3NME A;  2WTZ A;  3O4T A;  5KAB A;  3GXG A;  1YGR A;  1Q6T A;  2AM2 A;  1XXV A;  2JFF A;  3SME A;  1G4U S;  3HN7 A;  1I9S A;  3QKP A;  2WGP A;  1UAG A;  2JFH A;  1C87 A;  3D44 A;  2F6F A;  2I4E A;  2ESB A;  4HJQ A;  2CNE A;  2PT0 A;  2QBQ A;  2CM2 A;  2VOS A;  3V0F A;  1WCH A;  1OEO X;  2RF6 A;  3S3F A;  4ZRT A;  2NTA A;  3B7O A;  4JBC A;  4NWF A;  2CJZ A;  2UAG A;  1YPT A;  5KAD A;  1YTW A;  1W7K A;  2BGD A;  2I6M A;  1E0D A;  4NYH A;  2I4H A;  1U24 A;  5K9V A;  3AWG A;  2CMA A;  1VHR A;  3V0G A;  3UAG A;  2NLK A;  1GFY A;  2VEU A;  2CMB A;  4JMJ A;  3ZM1 A;  2QBS A;  4B04 A;  1YGU A;  3QCZ A;  4HRF A;  4YR8 B;  1MKP A;  3O4U A;  1YFO A;  2HC2 A;  4I8N A;  1C86 A;  1QZ0 A;  3AWF A;  3S3H A;  1GWZ A;  1NO6 A;  3OLR A;  5KAA A;  3RO1 A;  2H03 A;  2AZR A;  1OET A;  2R0B A;  3QCM A;  4BPC A;  1XXP A;  2CNG A;  3QCJ A;  1PTT A;  1ONY A;  2CFV A;  4OHL A;  4CVM A;  3A5J A;  1KAK A;  1Q6S A;  2Y66 A;  2PSZ A;  3S3K A;  4ERC A;  2P6X A;  1J6U A;  1JF7 A;  3D1Q A;  1AAX A;  2C46 A;  3A5K A;  3EU0 A;  2HNQ A;  5A5E A;  3D9C A;  1RPM A;  1G1H A;  4QDI A;  5KAC A;  5EHP A;  4QAP A;  1NL9 A;  1OHD A;  2I6P A;  4GWF A;  4GFU A;  5IBS A;  3I7Z A;  4NWG A;  1LYV A;  1PA1 A;  1FPZ A;  2B4S A;  3O5X A;  1EEN A;  3MVN A;  1QXK A;  2JFG A;  1YN9 A;  1E8C A;  3MMJ A;  3ZMP A;  1WAX A;  2FH7 A;  2CM3 A;  4RDD A;  2YDU A;  2VOR A;  1BZJ A;  2F6Z A;  1A5Y A;  2PA5 A;  3F99 A;  3QCG A;  2B4P A;  1Q6J A;  3EZZ A;  5KA3 A;  2UUO A;  2VEX A;  4ZI4 A;  2C7S A;  5KA4 A;  4ZIY A;  2F6W A;  1JLN A;  1T48 A;  4RH5 A;  2Q47 A;  4ZN5 A;  3U96 A;  4QBW A;  2GCA A;  4NX8 A;  3EMU A;  1J4X A;  4QF5 A;  1PYN A;  2NV5 A;  2B3O A;  1W78 A;  5K9W A;  2FJN A;  2XJA A;  3S4O A;  2NT7 A;  1OEM X;  1D5R A;  3RZ2 A;  2WJP A;  3NRS A;  1U26 A;  1ZCL A;  2I4G A;  2NT2 A;  3F9B A;  3QCD A;  3F9A A;  4RH9 A;  2HVL A;  1LQF A;  4RKK A;  2QDP A;  3V0D A;  2F6V A;  5AWX A;  2I42 A;  1O5Z A;  3D42 A;  5J8R A;  1P31 A;  3BM8 A;  3H2X A;  5KA1 A;  2F00 A;  2Q05 A;  4H34 A;  2I6O A;  1EEO A;  2OOQ A;  2GJT A;  2I3U A;  4GE2 A;  1ZCK A;  2H02 A;  3AWE A;  1NWE A;  2CM7 A;  2F71 A;  1NWL A;  1Q6N A;  4C12 A;  5BZX A;  3QCN A;  2A8B A;  3ZM5 A;  2GWO A;  3M4U A;  2G59 A;  2B49 A;  3EB1 A;  1BZC A;  1OES A;  5MMZ B;  1G1F A;  5A5F A;  4GE6 A;  4AZ1 A;  1YWF A;  2AHS A;  4R0S A;  1EEH A;  1PA9 A;  4GE5 A;  2B4U A;  1U25 A;  3D1H A;  2PI7 A;  3S3E A;  1I9T A;  2H04 A;  3QCE A;  4HJP A;  1P15 A;  4D3R A;  2F46 A;  1FGS A;  2OC3 A;  4YAA A;  2BIJ A;  2HNP A;  4NND A;  3MOZ A;  2Y2F A;  2DXP A;  4BJO A;  1WRM A;  3QCI A;  1SUG A;  4QAH A;  4CVL A;  4Y14 A;  1PTY A;  4D3Q A;  1X24 A;  5K25 A;  4QUM A;  3BLT A;  2BGE A;  5BZZ A;  4GFV A;  4QBE A;  1JBW A;  4TVV A;  4MBB A;  2M3V A;  2VEY A;  4RHG A;  1G7F A;  1V3A A;  3GXH A;  1OEV A;  3D1O A;  4DGP A;  5BX1 A;  4GS0 A;  3ZMQ A;  1GQQ A;  5EHR A;  5K22 A;  5K24 A;  1OEU A;  4ICZ A;  4OHI A;  3RGQ A;  2NZ6 A;  2Y1O A;  5IBM A;  2AM1 A;  1RXD A;  2GP0 A;  2I5X A;  1BZH A;  1C85 A;  4OHE A;  5BUG A;  1C84 A;  4WU2 A;  1PXH A;  4DGX A;  4KYR A;  3PYZ A;  2CNI A;  3I36 A;  4BUB A;  4RI4 A;  2CMC A;  2HC1 A;  1L8G A;  4CVK A;  1YTS A;  2E0T A;  1YZ4 A;  2B4O A;  2I3R A;  2QDM A;  2CNF A;  1G7G A;  5I6V A;  1G4W R;  2J17 A;  3F41 A;  5KA0 A;  2XPC A;  3LJ8 A;  4IKC A;  3MOW A;  1ECV A;  3N2A A;  1PTV A;  4OHD A; 
#chains in the Genus database with same CATH homology
 2IMG A;  3S4E A;  2QCJ A;  1XRI A;  2J16 B;  1Q6P A;  2F6T A;  1NZ7 A;  5KA7 A;  2QBR A;  1KAV A;  5KA9 A;  1ONZ A;  3O4S A;  4PVG A;  3V0I A;  3I80 A;  1XBO A;  5HDE A;  1L8K A;  1Q6M A;  1R6H A;  2B07 A;  1PTU A;  4H1O A;  4WOH A;  1FQ1 A;  4R30 A;  4PYH A;  2HY3 A;  2OUD A;  1T49 A;  1FPR A;  2H4G A;  1OHC A;  2ZMM A;  1Q1M A;  2G6Z A;  3QCH A;  2PBN A;  2SHP A;  4KYQ A;  3ZV2 A;  2BZL A;  2HB1 A;  2QCT A;  3O3L A;  2F6Y A;  2I6J A;  4R0T A;  1I57 A;  5KA2 A;  5K23 A;  3CWE A;  2PQ5 A;  3ZM2 A;  4Z6B A;  1M3G A;  3ZM0 A;  1NNY A;  3SR9 A;  2HXP A;  2CNH A;  4S0G A;  1OHE A;  3BLU A;  3QCF A;  1PH0 A;  2QEP A;  2VEV A;  3V0H A;  4GRY A;  3F81 A;  4JNB A;  3BRH A;  2A3K A;  3QCC A;  2HCM A;  2Y96 A;  2JJD A;  5GTJ A;  1XM2 A;  5KA8 A;  2VEW A;  1ZC0 A;  1LAR A;  3OMH A;  1YTN A;  2I1Y A;  2OZ5 A;  4KI9 A;  4GRZ A;  3V0E A;  2I6I A;  3RGO A;  4Y2E A;  1C83 A;  2BV5 A;  2J16 A;  4RI5 A;  1C88 A;  5LXQ B;  2ZN7 A;  3QCB A;  4QUN A;  5M43 A;  4J51 A;  2CM8 A;  2I75 A;  3ZM3 A;  2QBP A;  4JMK A;  3CM3 A;  3N0A A;  3QCL A;  2H4V A;  2F70 A;  4WU3 A;  2P4D A;  2MBC A;  3QKQ A;  4D3P A;  3PS5 A;  1ZZW A;  1G1G A;  2H4K A;  3EAX A;  3V0J A;  2FJM A;  4WTY A;  1T4J A;  4OHH A;  3QCK A;  2QDC A;  3NME A;  3O4T A;  5KAB A;  3GXG A;  1YGR A;  1Q6T A;  1XXV A;  3SME A;  1G4U S;  1I9S A;  3QKP A;  2WGP A;  1C87 A;  3D44 A;  2F6F A;  2I4E A;  2ESB A;  4HJQ A;  2CNE A;  2PT0 A;  2QBQ A;  2CM2 A;  3V0F A;  1WCH A;  1OEO X;  2RF6 A;  3S3F A;  4ZRT A;  2NTA A;  3B7O A;  4JBC A;  4NWF A;  2CJZ A;  1YPT A;  5KAD A;  1YTW A;  2BGD A;  2I6M A;  4NYH A;  2I4H A;  1U24 A;  5K9V A;  3AWG A;  2CMA A;  1VHR A;  3V0G A;  2NLK A;  1GFY A;  2VEU A;  2CMB A;  4JMJ A;  3ZM1 A;  2QBS A;  4B04 A;  1YGU A;  4YR8 B;  4HRF A;  1MKP A;  3O4U A;  1YFO A;  2HC2 A;  4I8N A;  1C86 A;  1QZ0 A;  3AWF A;  3S3H A;  1GWZ A;  1NO6 A;  3OLR A;  5KAA A;  3RO1 A;  2H03 A;  2AZR A;  1OET A;  2R0B A;  3QCM A;  4BPC A;  1XXP A;  2CNG A;  3QCJ A;  1PTT A;  1ONY A;  2CFV A;  4OHL A;  3A5J A;  1KAK A;  1Q6S A;  2PSZ A;  3S3K A;  4ERC A;  2P6X A;  1JF7 A;  3D1Q A;  1AAX A;  2C46 A;  3A5K A;  3EU0 A;  2HNQ A;  3D9C A;  1RPM A;  1G1H A;  5KAC A;  5EHP A;  4QAP A;  1NL9 A;  1OHD A;  2I6P A;  4GWF A;  4GFU A;  5IBS A;  3I7Z A;  4NWG A;  1LYV A;  1PA1 A;  1FPZ A;  2B4S A;  3O5X A;  1EEN A;  1QXK A;  1YN9 A;  3MMJ A;  3ZMP A;  1WAX A;  2FH7 A;  2CM3 A;  4RDD A;  2YDU A;  1BZJ A;  2F6Z A;  1A5Y A;  2PA5 A;  3F99 A;  3QCG A;  2B4P A;  1Q6J A;  3EZZ A;  5KA3 A;  2VEX A;  4ZI4 A;  2C7S A;  5KA4 A;  2F6W A;  1JLN A;  1T48 A;  4RH5 A;  2Q47 A;  4ZN5 A;  3U96 A;  4QBW A;  4NX8 A;  3EMU A;  1J4X A;  1PYN A;  2NV5 A;  2B3O A;  5K9W A;  2FJN A;  3S4O A;  2NT7 A;  1OEM X;  1D5R A;  3RZ2 A;  1U26 A;  1ZCL A;  2I4G A;  2NT2 A;  3F9B A;  3QCD A;  3F9A A;  4RH9 A;  2HVL A;  1LQF A;  4RKK A;  2QDP A;  3V0D A;  2F6V A;  5AWX A;  2I42 A;  3D42 A;  5J8R A;  3BM8 A;  3H2X A;  5KA1 A;  2Q05 A;  4H34 A;  2I6O A;  1EEO A;  2OOQ A;  2GJT A;  2I3U A;  4GE2 A;  1ZCK A;  2H02 A;  3AWE A;  1NWE A;  2CM7 A;  2F71 A;  1NWL A;  1Q6N A;  5BZX A;  3QCN A;  2A8B A;  2GWO A;  3M4U A;  2G59 A;  2B49 A;  3EB1 A;  1BZC A;  1OES A;  5MMZ B;  1G1F A;  4GE6 A;  4AZ1 A;  1YWF A;  2AHS A;  4R0S A;  1PA9 A;  4GE5 A;  2B4U A;  1U25 A;  3D1H A;  2PI7 A;  3S3E A;  1I9T A;  2H04 A;  3QCE A;  4HJP A;  1P15 A;  4D3R A;  2F46 A;  4YAA A;  2OC3 A;  2BIJ A;  2HNP A;  4NND A;  3MOZ A;  2Y2F A;  2DXP A;  4BJO A;  1WRM A;  3QCI A;  1SUG A;  4QAH A;  4Y14 A;  1PTY A;  4D3Q A;  1X24 A;  5K25 A;  4QUM A;  3BLT A;  2BGE A;  5BZZ A;  4GFV A;  4QBE A;  4TVV A;  4MBB A;  2M3V A;  2VEY A;  4RHG A;  1G7F A;  1V3A A;  3GXH A;  1OEV A;  3D1O A;  4DGP A;  5BX1 A;  4GS0 A;  3ZMQ A;  5EHR A;  5K22 A;  5K24 A;  1OEU A;  4ICZ A;  4OHI A;  3RGQ A;  2NZ6 A;  5IBM A;  1RXD A;  2GP0 A;  2I5X A;  1BZH A;  1C85 A;  4OHE A;  5BUG A;  1C84 A;  4WU2 A;  1PXH A;  4DGX A;  4KYR A;  2CNI A;  3I36 A;  4RI4 A;  2CMC A;  2HC1 A;  1L8G A;  1YTS A;  2E0T A;  1YZ4 A;  2B4O A;  2I3R A;  2QDM A;  2CNF A;  1G7G A;  5I6V A;  1G4W R;  2J17 A;  3F41 A;  5KA0 A;  3LJ8 A;  4IKC A;  3MOW A;  1ECV A;  1PTV A;  4OHD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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