1M3GA

Solution structure of the catalytic domain of mapk phosphatase pac-1: insights into substrate-induced enzymatic activation
Total Genus 29
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
145
structure length
145
Chain Sequence
QGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHSQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structure of the MAPK Phosphatase PAC-1 Catalytic Domain Insights into Substrate-Induced Enzymatic Activation of MKP
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords DUAL SPECIFICITY PROTEIN PHOSPHATASE 2
total genus 29
structure length 145
sequence length 145
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2002-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1m3gA00
2H04A 2ZN7A 4BJOA 2HNPA 1X24A 3BLUA 4GS0A 2I42A 4YAAA 3ZM2A 1ZCKA 3CM3A 2I5XA 4D3RA 3O3LA 5BZXA 1JF7A 5K22A 3I7ZA 1ZZWA 3SMEA 5EHRA 1YGUA 1Q6JA 4QAPA 2BIJA 2OZ5A 3F41A 3AWFA 3EMUA 2B4PA 2QBPA 3QKPA 3EB1A 3O4UA 2PA5A 4D3QA 1G7FA 2HB1A 2I75A 1YGRA 2VEVA 1Q6PA 4NWGA 3D1HA 5KAAA 2B4OA 1PA9A 3AWEA 4ZI4A 5K9VA 1JLNA 2G6ZA 3BM8A 4OHLA 4R30A 5KA0A 2CM8A 3V0GA 4GE5A 1ZC0A 2B3OA 5MMZB 1OEOX 2I6MA 4GE2A 2B4UA 1YN9A 2HVLA 3ZMPA 4B04A 1R6HA 2F71A 5KA4A 1I9SA 4RDDA 3ZV2A 2BV5A 4OHEA 4GRYA 1XXVA 2F6FA 2VEYA 1PYNA 1YTSA 3D9CA 4NWFA 5AWXA 1PXHA 3CWEA 5KADA 4I8NA 2CNIA 1U24A 2H4GA 5HDEA 1ONYA 2A3KA 3QCDA 1SUGA 1GFYA 1NNYA 1V3AA 3S3HA 3ZM3A 2OOQA 3V0EA 3QCNA 2QBQA 1WRMA 1NWEA 4OHHA 2QEPA 4QUMA 3MOZA 2P4DA 3F9BA 4WU3A 3H2XA 2FJMA 4H1OA 4ERCA 2J16A 1PTYA 1XRIA 2I4HA 3S4EA 4R0SA 2HY3A 2QCTA 5IBMA 2M3VA 3V0DA 2CM7A 4QBEA 4QUNA 3N0AA 1Q6TA 2CMBA 1AAXA 1VHRA 4OHDA 3RGOA 3ZM0A 2Q05A 4JMJA 2MBCA 3QCEA 2CJZA 2CM2A 2PBNA 2YDUA 1I57A 2CM3A 4RHGA 4Z6BA 1OHDA 2F6YA 2HC2A 3S4OA 3ZMQA 2A8BA 2AHSA 3QCBA 2I6JA 1I9TA 2B07A 2OC3A 2PQ5A 1OEVA 2PT0A 2R0BA 4PYHA 3SR9A 2H4VA 1NL9A 2WGPA 5M43A 1T4JA 1YWFA 1WCHA 4DGXA 1G7GA 2J16B 4GWFA 3QCIA 3ZM1A 1KAKA 3RGQA 1L8KA 4OHIA 2F6ZA 2HC1A 2HCMA 1C86A 2P6XA 4TVVA 1PA1A 3A5JA 3NMEA 1KAVA 2Q47A 5KABA 3V0IA 1Q6MA 3O5XA 1YZ4A 2H02A 4RH9A 2GWOA 1NWLA 3QCJA 5J8RA 1OEMX 1G4WR 1Q1MA 5KA7A 1OHEA 2I3RA 3QCMA 2I4EA 2PSZA 1ONZA 1Q6SA 5K23A 2BGDA 2NTAA 4Y2EA 1MKPA 4KI9A 1ZCLA 3F99A 4KYQA 1BZJA 1P15A 2Y2FA 3D44A 2JJDA 4GE6A 4RI5A 1OETA 1PTUA 2NT2A 3BLTA 2H03A 1RXDA 1ECVA 1LQFA 2F6TA 1PH0A 5KA1A 1U26A 3F81A 5LXQB 1D5RA 2CFVA 2ZMMA 2I6IA 5GTJA 4HJQA 2QBSA 4ZN5A 2CNGA 2QBRA 2DXPA 4QAHA 1YTWA 2F46A 4JMKA 2CMAA 2QDMA 2GP0A 5K9WA 2NLKA 1XXPA 2VEUA 3EAXA 4BPCA 3B7OA 4WU2A 1C88A 4R0TA 2RF6A 1T49A 3I36A 3GXHA 5K25A 2CNFA 4WTYA 4IKCA 4AZ1A 1T48A 2B4SA 3BRHA 3QCHA 2IMGA 2H4KA 1XBOA 4RKKA 3F9AA 5IBSA 1RPMA 1J4XA 1QZ0A 3M4UA 2BZLA 2QCJA 2I1YA 2NT7A 4RH5A 4MBBA 2PI7A 5EHPA 4RI4A 2QDPA 4Y14A 2I6PA 2VEXA 4PVGA 4H34A 4D3PA 2CNHA 4NNDA 1FPZA 1C83A 1G1HA 3S3KA 2B49A 1A5YA 1C84A 3RO1A 3D42A 3O4TA 3V0HA 1OHCA 2AZRA 1PTVA 1YTNA 1PTTA 3QCFA 1Q6NA 2I4GA 3A5KA 1YFOA 1C87A 1GWZA 2GJTA 3QCLA 4NX8A 4GRZA 1G1FA 3AWGA 3QCKA 4ZRTA 3QKQA 3I80A 2VEWA 3V0FA 4HJPA 2I3UA 3OMHA 1EEOA 1OESA 5BUGA 3D1OA 1XM2A 1BZCA 1U25A 4GFVA 2J17A 3RZ2A 3U96A 3MOWA 2FJNA 3S3EA 3PS5A 2F6WA 4JBCA 2F70A 1NZ7A 3OLRA 4DGPA 4YR8B 1G1GA 2ESBA 1EENA 3GXGA 2I6OA 3LJ8A 2CMCA 1WAXA 4JNBA 2C7SA 3V0JA 2BGEA 4J51A 4ICZA 2QDCA 1BZHA 1M3GA 3O4SA 4NYHA 2SHPA 2F6VA 1QXKA 2FH7A 1FPRA 3EU0A 2HXPA 1OEUA 2NV5A 2CNEA 5KACA 1FQ1A 5KA2A 5KA8A 2E0TA 4GFUA 3QCCA 2C46A 1YPTA 4HRFA 4QBWA 4KYRA 1G4US 5KA3A 4S0GA 1L8GA 3D1QA 3EZZA 1LARA 2G59A 1LYVA 2HNQA 2Y96A 5I6VA 1NO6A 1C85A 2OUDA 3S3FA 5BZZA 5KA9A 3MMJA 3QCGA 4WOHA 5K24A 5BX1A 2NZ6A
chains in the Genus database with same CATH superfamily
2VTDA 2H04A 2ZN7A 4BJOA 2HNPA 1X24A 3BLUA 4GS0A 2I42A 4YAAA 3ZM2A 1ZCKA 3CM3A 2I5XA 4D3RA 5A5EA 3O3LA 5BZXA 1JF7A 5K22A 3I7ZA 1ZZWA 3SMEA 2WTZA 1YGUA 1Q6JA 5EHRA 3LK7A 4QAPA 1GQQA 3UAGA 2BIJA 2OZ5A 3F41A 3AWFA 3EMUA 2B4PA 1J6UA 4HV4A 1EEHA 2QBPA 3QKPA 3EB1A 3O4UA 3ZL8A 2PA5A 4D3QA 1G7FA 2HB1A 2I75A 1YGRA 4C12A 4CVLA 2VEVA 1Q6PA 4NWGA 1JBVA 3D1HA 5KAAA 2B4OA 2JFFA 1PA9A 3AWEA 4ZI4A 5K9VA 1JLNA 2G6ZA 3BM8A 4OHLA 4R30A 5KA0A 2CM8A 3V0GA 4GE5A 1ZC0A 2B3OA 5MMZB 1OEOX 2I6MA 4GE2A 2B4UA 1YN9A 2HVLA 4QDIA 3ZMPA 4B04A 1R6HA 2F71A 5KA4A 1I9SA 4RDDA 3ZV2A 1FGSA 2BV5A 4OHEA 4GRYA 1GG4A 1XXVA 2F6FA 2VEYA 1PYNA 1YTSA 3D9CA 4NWFA 4UAGA 5AWXA 1PXHA 3CWEA 5KADA 4I8NA 2CNIA 1U24A 1E0DA 2H4GA 5HDEA 1ONYA 2GCAA 2A3KA 3QCDA 1SUGA 2JFGA 1GFYA 1NNYA 1V3AA 2AM2A 3S3HA 3ZM3A 2OOQA 3V0EA 3QCNA 2QBQA 1WRMA 1NWEA 4OHHA 2AM1A 2QEPA 3NRSA 4QUMA 4QF5A 3MOZA 2P4DA 3F9BA 4WU3A 3H2XA 5A5FA 2FJMA 4H1OA 4ERCA 2J16A 1PTYA 1XRIA 2I4HA 3S4EA 3ZM5A 4R0SA 2HY3A 2QCTA 5IBMA 2M3VA 3V0DA 2CM7A 4QBEA 4QUNA 3N0AA 1Q6TA 2CMBA 1AAXA 1VHRA 4OHDA 3RGOA 3ZM0A 2Q05A 4JMJA 2MBCA 3QCEA 2CJZA 2CM2A 2PBNA 2YDUA 1I57A 2CM3A 3MVNA 4RHGA 4Z6BA 1OHDA 2F6YA 2UUPA 2GCBA 2HC2A 3PYZA 3S4OA 3ZMQA 2A8BA 2AHSA 3QCBA 2I6JA 1I9TA 4CVMA 2B07A 2OC3A 2PQ5A 1OEVA 2PT0A 2R0BA 4PYHA 3SR9A 2H4VA 1NL9A 2WGPA 5M43A 1T4JA 1YWFA 1WCHA 4DGXA 1W7KA 1G7GA 2J16B 4GWFA 3QCIA 1O5ZA 3ZM1A 1KAKA 3RGQA 1L8KA 4OHIA 2F6ZA 2HC1A 2HCMA 1C86A 2P6XA 4TVVA 1PA1A 3A5JA 3NMEA 1KAVA 2Q47A 2VORA 5KABA 3V0IA 1Q6MA 3O5XA 1YZ4A 2H02A 4RH9A 2GWOA 4C13A 1NWLA 3QCJA 2VTEA 5J8RA 1OEMX 1G4WR 3N2AA 1Q1MA 5KA7A 1OHEA 1JBWA 2I3RA 3QCMA 2I4EA 2PSZA 1ONZA 1Q6SA 5K23A 2BGDA 2NTAA 4Y2EA 4BUCA 1MKPA 4KI9A 1ZCLA 1GQYA 3F99A 4KYQA 2Y66A 1BZJA 1P15A 2Y2FA 3D44A 2JJDA 4GE6A 4RI5A 1OETA 1PTUA 2NT2A 3BLTA 2H03A 1RXDA 1ECVA 2F00A 1LQFA 2F6TA 1PH0A 5KA1A 1U26A 3F81A 5LXQB 1D5RA 2CFVA 2ZMMA 2I6IA 5GTJA 4HJQA 2QBSA 4ZN5A 2CNGA 2QBRA 2DXPA 4QAHA 1YTWA 2F46A 4JMKA 2CMAA 2QDMA 2GP0A 1E8CA 5K9WA 2NLKA 1XXPA 2VEUA 3EAXA 1UAGA 4BPCA 3B7OA 4WU2A 1C88A 4R0TA 2RF6A 1T49A 3I36A 3GXHA 5K25A 2CNFA 4WTYA 4IKCA 1W78A 4AZ1A 1T48A 2B4SA 2XPCA 3BRHA 3QCHA 2IMGA 2H4KA 1XBOA 4RKKA 3F9AA 5IBSA 1RPMA 1J4XA 4ZIYA 1QZ0A 3M4UA 2BZLA 2QCJA 2I1YA 2NT7A 4RH5A 4MBBA 2PI7A 5EHPA 2Y1OA 4RI4A 3HN7A 2QDPA 4Y14A 2I6PA 2VEXA 4PVGA 4H34A 4D3PA 2CNHA 4NNDA 1FPZA 1C83A 1G1HA 3S3KA 2UUOA 2B49A 1A5YA 1C84A 3RO1A 3D42A 3O4TA 3V0HA 2Y67A 1OHCA 2AZRA 1PTVA 1YTNA 1PTTA 3QCFA 1Q6NA 2I4GA 3A5KA 1YFOA 1C87A 1GWZA 2GJTA 3QCLA 4NX8A 4GRZA 1G1FA 3AWGA 3QCKA 4ZRTA 3QKQA 4CVKA 3I80A 2WJPA 2VEWA 3V0FA 4HJPA 2I3UA 3OMHA 1EEOA 1OESA 5BUGA 3D1OA 1XM2A 1BZCA 1U25A 4GFVA 2J17A 3RZ2A 3U96A 3MOWA 2FJNA 3S3EA 3PS5A 2F6WA 4JBCA 2F70A 2VOSA 1NZ7A 3OLRA 4DGPA 4YR8B 1G1GA 2ESBA 2X5OA 1P31A 1EENA 3GXGA 2I6OA 3LJ8A 2CMCA 3QCZA 1WAXA 4JNBA 2C7SA 3V0JA 2BGEA 4J51A 4ICZA 2QDCA 2GC6A 1BZHA 1M3GA 3O4SA 2UAGA 4NYHA 2SHPA 2F6VA 1QXKA 2FH7A 1FPRA 3EU0A 2GC5A 2HXPA 1OEUA 2NV5A 2CNEA 5KACA 1FQ1A 5KA2A 5KA8A 2Y68A 2JFHA 2E0TA 4GFUA 3QCCA 2C46A 1YPTA 2XJAA 4HRFA 4QBWA 4KYRA 1G4US 5KA3A 4S0GA 1L8GA 1P3DA 3D1QA 3EZZA 3ZM6A 1LARA 2G59A 1LYVA 2HNQA 2Y96A 5I6VA 1NO6A 1C85A 2OUDA 3S3FA 5BZZA 5KA9A 3MMJA 3QCGA 4BUBA 4WOHA 5K24A 5BX1A 2NZ6A
chains in the Genus database with same CATH topology
2H04A 2ZN7A 4BJOA 2HNPA 1X24A 3BLUA 4GS0A 2I42A 4YAAA 3ZM2A 1ZCKA 3CM3A 2I5XA 4D3RA 3O3LA 5BZXA 1JF7A 5K22A 3I7ZA 1ZZWA 3SMEA 5EHRA 1YGUA 1Q6JA 4QAPA 2BIJA 2OZ5A 3F41A 3AWFA 3EMUA 2B4PA 2QBPA 3QKPA 3EB1A 3O4UA 2PA5A 4D3QA 1G7FA 2HB1A 2I75A 1YGRA 2VEVA 1Q6PA 4NWGA 3D1HA 5KAAA 2B4OA 1PA9A 3AWEA 4ZI4A 5K9VA 1JLNA 2G6ZA 3BM8A 4OHLA 4R30A 5KA0A 2CM8A 3V0GA 4GE5A 1ZC0A 2B3OA 5MMZB 1OEOX 2I6MA 4GE2A 2B4UA 1YN9A 2HVLA 3ZMPA 4B04A 1R6HA 2F71A 5KA4A 1I9SA 4RDDA 3ZV2A 2BV5A 4OHEA 4GRYA 1XXVA 2F6FA 2VEYA 1PYNA 1YTSA 3D9CA 4NWFA 5AWXA 1PXHA 3CWEA 5KADA 4I8NA 2CNIA 1U24A 2H4GA 5HDEA 1ONYA 2A3KA 3QCDA 1SUGA 1GFYA 1NNYA 1V3AA 3S3HA 3ZM3A 2OOQA 3V0EA 3QCNA 2QBQA 1WRMA 1NWEA 4OHHA 2QEPA 4QUMA 3MOZA 2P4DA 3F9BA 4WU3A 3H2XA 2FJMA 4H1OA 4ERCA 2J16A 1PTYA 1XRIA 2I4HA 3S4EA 4R0SA 2HY3A 2QCTA 5IBMA 2M3VA 3V0DA 2CM7A 4QBEA 4QUNA 3N0AA 1Q6TA 2CMBA 1AAXA 1VHRA 4OHDA 3RGOA 3ZM0A 2Q05A 4JMJA 2MBCA 3QCEA 2CJZA 2CM2A 2PBNA 2YDUA 1I57A 2CM3A 4RHGA 4Z6BA 1OHDA 2F6YA 2HC2A 3S4OA 3ZMQA 2A8BA 2AHSA 3QCBA 2I6JA 1I9TA 2B07A 2OC3A 2PQ5A 1OEVA 2PT0A 2R0BA 4PYHA 3SR9A 2H4VA 1NL9A 2WGPA 5M43A 1T4JA 1YWFA 1WCHA 4DGXA 1G7GA 2J16B 4GWFA 3QCIA 3ZM1A 1KAKA 3RGQA 1L8KA 4OHIA 2F6ZA 2HC1A 2HCMA 1C86A 2P6XA 4TVVA 1PA1A 3A5JA 3NMEA 1KAVA 2Q47A 5KABA 3V0IA 1Q6MA 3O5XA 1YZ4A 2H02A 4RH9A 2GWOA 1NWLA 3QCJA 5J8RA 1OEMX 1G4WR 1Q1MA 5KA7A 1OHEA 2I3RA 3QCMA 2I4EA 2PSZA 1ONZA 1Q6SA 5K23A 2BGDA 2NTAA 4Y2EA 1MKPA 4KI9A 1ZCLA 3F99A 4KYQA 1BZJA 1P15A 2Y2FA 3D44A 2JJDA 4GE6A 4RI5A 1OETA 1PTUA 2NT2A 3BLTA 2H03A 1RXDA 1ECVA 1LQFA 2F6TA 1PH0A 5KA1A 1U26A 3F81A 5LXQB 1D5RA 2CFVA 2ZMMA 2I6IA 5GTJA 4HJQA 2QBSA 4ZN5A 2CNGA 2QBRA 2DXPA 4QAHA 1YTWA 2F46A 4JMKA 2CMAA 2QDMA 2GP0A 5K9WA 2NLKA 1XXPA 2VEUA 3EAXA 4BPCA 3B7OA 4WU2A 1C88A 4R0TA 2RF6A 1T49A 3I36A 3GXHA 5K25A 2CNFA 4WTYA 4IKCA 4AZ1A 1T48A 2B4SA 3BRHA 3QCHA 2IMGA 2H4KA 1XBOA 4RKKA 3F9AA 5IBSA 1RPMA 1J4XA 1QZ0A 3M4UA 2BZLA 2QCJA 2I1YA 2NT7A 4RH5A 4MBBA 2PI7A 5EHPA 4RI4A 2QDPA 4Y14A 2I6PA 2VEXA 4PVGA 4H34A 4D3PA 2CNHA 4NNDA 1FPZA 1C83A 1G1HA 3S3KA 2B49A 1A5YA 1C84A 3RO1A 3D42A 3O4TA 3V0HA 1OHCA 2AZRA 1PTVA 1YTNA 1PTTA 3QCFA 1Q6NA 2I4GA 3A5KA 1YFOA 1C87A 1GWZA 2GJTA 3QCLA 4NX8A 4GRZA 1G1FA 3AWGA 3QCKA 4ZRTA 3QKQA 3I80A 2VEWA 3V0FA 4HJPA 2I3UA 3OMHA 1EEOA 1OESA 5BUGA 3D1OA 1XM2A 1BZCA 1U25A 4GFVA 2J17A 3RZ2A 3U96A 3MOWA 2FJNA 3S3EA 3PS5A 2F6WA 4JBCA 2F70A 1NZ7A 3OLRA 4DGPA 4YR8B 1G1GA 2ESBA 1EENA 3GXGA 2I6OA 3LJ8A 2CMCA 1WAXA 4JNBA 2C7SA 3V0JA 2BGEA 4J51A 4ICZA 2QDCA 1BZHA 1M3GA 3O4SA 4NYHA 2SHPA 2F6VA 1QXKA 2FH7A 1FPRA 3EU0A 2HXPA 1OEUA 2NV5A 2CNEA 5KACA 1FQ1A 5KA2A 5KA8A 2E0TA 4GFUA 3QCCA 2C46A 1YPTA 4HRFA 4QBWA 4KYRA 1G4US 5KA3A 4S0GA 1L8GA 3D1QA 3EZZA 1LARA 2G59A 1LYVA 2HNQA 2Y96A 5I6VA 1NO6A 1C85A 2OUDA 3S3FA 5BZZA 5KA9A 3MMJA 3QCGA 4WOHA 5K24A 5BX1A 2NZ6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H04 A;  2ZN7 A;  4BJO A;  2HNP A;  1X24 A;  3BLU A;  4GS0 A;  2I42 A;  4YAA A;  3ZM2 A;  1ZCK A;  3CM3 A;  2I5X A;  4D3R A;  3O3L A;  5BZX A;  1JF7 A;  5K22 A;  3I7Z A;  1ZZW A;  3SME A;  5EHR A;  1YGU A;  1Q6J A;  4QAP A;  2BIJ A;  2OZ5 A;  3F41 A;  3AWF A;  3EMU A;  2B4P A;  2QBP A;  3QKP A;  3EB1 A;  3O4U A;  2PA5 A;  4D3Q A;  1G7F A;  2HB1 A;  2I75 A;  1YGR A;  2VEV A;  1Q6P A;  4NWG A;  3D1H A;  5KAA A;  2B4O A;  1PA9 A;  3AWE A;  4ZI4 A;  5K9V A;  1JLN A;  2G6Z A;  3BM8 A;  4OHL A;  4R30 A;  5KA0 A;  2CM8 A;  3V0G A;  4GE5 A;  1ZC0 A;  2B3O A;  5MMZ B;  1OEO X;  2I6M A;  4GE2 A;  2B4U A;  1YN9 A;  2HVL A;  3ZMP A;  4B04 A;  1R6H A;  2F71 A;  5KA4 A;  1I9S A;  4RDD A;  3ZV2 A;  2BV5 A;  4OHE A;  4GRY A;  1XXV A;  2F6F A;  2VEY A;  1PYN A;  1YTS A;  3D9C A;  4NWF A;  5AWX A;  1PXH A;  3CWE A;  5KAD A;  4I8N A;  2CNI A;  1U24 A;  2H4G A;  5HDE A;  1ONY A;  2A3K A;  3QCD A;  1SUG A;  1GFY A;  1NNY A;  1V3A A;  3S3H A;  3ZM3 A;  2OOQ A;  3V0E A;  3QCN A;  2QBQ A;  1WRM A;  1NWE A;  4OHH A;  2QEP A;  4QUM A;  3MOZ A;  2P4D A;  3F9B A;  4WU3 A;  3H2X A;  2FJM A;  4H1O A;  4ERC A;  2J16 A;  1PTY A;  1XRI A;  2I4H A;  3S4E A;  4R0S A;  2HY3 A;  2QCT A;  5IBM A;  2M3V A;  3V0D A;  2CM7 A;  4QBE A;  4QUN A;  3N0A A;  1Q6T A;  2CMB A;  1AAX A;  1VHR A;  4OHD A;  3RGO A;  3ZM0 A;  2Q05 A;  4JMJ A;  2MBC A;  3QCE A;  2CJZ A;  2CM2 A;  2PBN A;  2YDU A;  1I57 A;  2CM3 A;  4RHG A;  4Z6B A;  1OHD A;  2F6Y A;  2HC2 A;  3S4O A;  3ZMQ A;  2A8B A;  2AHS A;  3QCB A;  2I6J A;  1I9T A;  2B07 A;  2OC3 A;  2PQ5 A;  1OEV A;  2PT0 A;  2R0B A;  4PYH A;  3SR9 A;  2H4V A;  1NL9 A;  2WGP A;  5M43 A;  1T4J A;  1YWF A;  1WCH A;  4DGX A;  1G7G A;  2J16 B;  4GWF A;  3QCI A;  3ZM1 A;  1KAK A;  3RGQ A;  1L8K A;  4OHI A;  2F6Z A;  2HC1 A;  2HCM A;  1C86 A;  2P6X A;  4TVV A;  1PA1 A;  3A5J A;  3NME A;  1KAV A;  2Q47 A;  5KAB A;  3V0I A;  1Q6M A;  3O5X A;  1YZ4 A;  2H02 A;  4RH9 A;  2GWO A;  1NWL A;  3QCJ A;  5J8R A;  1OEM X;  1G4W R;  1Q1M A;  5KA7 A;  1OHE A;  2I3R A;  3QCM A;  2I4E A;  2PSZ A;  1ONZ A;  1Q6S A;  5K23 A;  2BGD A;  2NTA A;  4Y2E A;  1MKP A;  4KI9 A;  1ZCL A;  3F99 A;  4KYQ A;  1BZJ A;  1P15 A;  2Y2F A;  3D44 A;  2JJD A;  4GE6 A;  4RI5 A;  1OET A;  1PTU A;  2NT2 A;  3BLT A;  2H03 A;  1RXD A;  1ECV A;  1LQF A;  2F6T A;  1PH0 A;  5KA1 A;  1U26 A;  3F81 A;  5LXQ B;  1D5R A;  2CFV A;  2ZMM A;  2I6I A;  5GTJ A;  4HJQ A;  2QBS A;  4ZN5 A;  2CNG A;  2QBR A;  2DXP A;  4QAH A;  1YTW A;  2F46 A;  4JMK A;  2CMA A;  2QDM A;  2GP0 A;  5K9W A;  2NLK A;  1XXP A;  2VEU A;  3EAX A;  4BPC A;  3B7O A;  4WU2 A;  1C88 A;  4R0T A;  2RF6 A;  1T49 A;  3I36 A;  3GXH A;  5K25 A;  2CNF A;  4WTY A;  4IKC A;  4AZ1 A;  1T48 A;  2B4S A;  3BRH A;  3QCH A;  2IMG A;  2H4K A;  1XBO A;  4RKK A;  3F9A A;  5IBS A;  1RPM A;  1J4X A;  1QZ0 A;  3M4U A;  2BZL A;  2QCJ A;  2I1Y A;  2NT7 A;  4RH5 A;  4MBB A;  2PI7 A;  5EHP A;  4RI4 A;  2QDP A;  4Y14 A;  2I6P A;  2VEX A;  4PVG A;  4H34 A;  4D3P A;  2CNH A;  4NND A;  1FPZ A;  1C83 A;  1G1H A;  3S3K A;  2B49 A;  1A5Y A;  1C84 A;  3RO1 A;  3D42 A;  3O4T A;  3V0H A;  1OHC A;  2AZR A;  1PTV A;  1YTN A;  1PTT A;  3QCF A;  1Q6N A;  2I4G A;  3A5K A;  1YFO A;  1C87 A;  1GWZ A;  2GJT A;  3QCL A;  4NX8 A;  4GRZ A;  1G1F A;  3AWG A;  3QCK A;  4ZRT A;  3QKQ A;  3I80 A;  2VEW A;  3V0F A;  4HJP A;  2I3U A;  3OMH A;  1EEO A;  1OES A;  5BUG A;  3D1O A;  1XM2 A;  1BZC A;  1U25 A;  4GFV A;  2J17 A;  3RZ2 A;  3U96 A;  3MOW A;  2FJN A;  3S3E A;  3PS5 A;  2F6W A;  4JBC A;  2F70 A;  1NZ7 A;  3OLR A;  4DGP A;  4YR8 B;  1G1G A;  2ESB A;  1EEN A;  3GXG A;  2I6O A;  3LJ8 A;  2CMC A;  1WAX A;  4JNB A;  2C7S A;  3V0J A;  2BGE A;  4J51 A;  4ICZ A;  2QDC A;  1BZH A;  1M3G A;  3O4S A;  4NYH A;  2SHP A;  2F6V A;  1QXK A;  2FH7 A;  1FPR A;  3EU0 A;  2HXP A;  1OEU A;  2NV5 A;  2CNE A;  5KAC A;  1FQ1 A;  5KA2 A;  5KA8 A;  2E0T A;  4GFU A;  3QCC A;  2C46 A;  1YPT A;  4HRF A;  4QBW A;  4KYR A;  1G4U S;  5KA3 A;  4S0G A;  1L8G A;  3D1Q A;  3EZZ A;  1LAR A;  2G59 A;  1LYV A;  2HNQ A;  2Y96 A;  5I6V A;  1NO6 A;  1C85 A;  2OUD A;  3S3F A;  5BZZ A;  5KA9 A;  3MMJ A;  3QCG A;  4WOH A;  5K24 A;  5BX1 A;  2NZ6 A; 
#chains in the Genus database with same CATH topology
 2VTD A;  2H04 A;  2ZN7 A;  4BJO A;  2HNP A;  1X24 A;  3BLU A;  4GS0 A;  2I42 A;  4YAA A;  3ZM2 A;  1ZCK A;  3CM3 A;  2I5X A;  4D3R A;  5A5E A;  3O3L A;  5BZX A;  1JF7 A;  5K22 A;  3I7Z A;  1ZZW A;  3SME A;  2WTZ A;  1YGU A;  1Q6J A;  5EHR A;  3LK7 A;  4QAP A;  1GQQ A;  3UAG A;  2BIJ A;  2OZ5 A;  3F41 A;  3AWF A;  3EMU A;  2B4P A;  1J6U A;  4HV4 A;  1EEH A;  2QBP A;  3QKP A;  3EB1 A;  3O4U A;  3ZL8 A;  2PA5 A;  4D3Q A;  1G7F A;  2HB1 A;  2I75 A;  1YGR A;  4C12 A;  4CVL A;  2VEV A;  1Q6P A;  4NWG A;  1JBV A;  3D1H A;  5KAA A;  2B4O A;  2JFF A;  1PA9 A;  3AWE A;  4ZI4 A;  5K9V A;  1JLN A;  2G6Z A;  3BM8 A;  4OHL A;  4R30 A;  5KA0 A;  2CM8 A;  3V0G A;  4GE5 A;  1ZC0 A;  2B3O A;  5MMZ B;  1OEO X;  2I6M A;  4GE2 A;  2B4U A;  1YN9 A;  2HVL A;  4QDI A;  3ZMP A;  4B04 A;  1R6H A;  2F71 A;  5KA4 A;  1I9S A;  4RDD A;  3ZV2 A;  1FGS A;  2BV5 A;  4OHE A;  4GRY A;  1GG4 A;  1XXV A;  2F6F A;  2VEY A;  1PYN A;  1YTS A;  3D9C A;  4NWF A;  4UAG A;  5AWX A;  1PXH A;  3CWE A;  5KAD A;  4I8N A;  2CNI A;  1U24 A;  1E0D A;  2H4G A;  5HDE A;  1ONY A;  2GCA A;  2A3K A;  3QCD A;  1SUG A;  2JFG A;  1GFY A;  1NNY A;  1V3A A;  2AM2 A;  3S3H A;  3ZM3 A;  2OOQ A;  3V0E A;  3QCN A;  2QBQ A;  1WRM A;  1NWE A;  4OHH A;  2AM1 A;  2QEP A;  3NRS A;  4QUM A;  4QF5 A;  3MOZ A;  2P4D A;  3F9B A;  4WU3 A;  3H2X A;  5A5F A;  2FJM A;  4H1O A;  4ERC A;  2J16 A;  1PTY A;  1XRI A;  2I4H A;  3S4E A;  3ZM5 A;  4R0S A;  2HY3 A;  2QCT A;  5IBM A;  2M3V A;  3V0D A;  2CM7 A;  4QBE A;  4QUN A;  3N0A A;  1Q6T A;  2CMB A;  1AAX A;  1VHR A;  4OHD A;  3RGO A;  3ZM0 A;  2Q05 A;  4JMJ A;  2MBC A;  3QCE A;  2CJZ A;  2CM2 A;  2PBN A;  2YDU A;  1I57 A;  2CM3 A;  3MVN A;  4RHG A;  4Z6B A;  1OHD A;  2F6Y A;  2UUP A;  2GCB A;  2HC2 A;  3PYZ A;  3S4O A;  3ZMQ A;  2A8B A;  2AHS A;  3QCB A;  2I6J A;  1I9T A;  4CVM A;  2B07 A;  2OC3 A;  2PQ5 A;  1OEV A;  2PT0 A;  2R0B A;  4PYH A;  3SR9 A;  2H4V A;  1NL9 A;  2WGP A;  5M43 A;  1T4J A;  1YWF A;  1WCH A;  4DGX A;  1W7K A;  1G7G A;  2J16 B;  4GWF A;  3QCI A;  1O5Z A;  3ZM1 A;  1KAK A;  3RGQ A;  1L8K A;  4OHI A;  2F6Z A;  2HC1 A;  2HCM A;  1C86 A;  2P6X A;  4TVV A;  1PA1 A;  3A5J A;  3NME A;  1KAV A;  2Q47 A;  2VOR A;  5KAB A;  3V0I A;  1Q6M A;  3O5X A;  1YZ4 A;  2H02 A;  4RH9 A;  2GWO A;  4C13 A;  1NWL A;  3QCJ A;  2VTE A;  5J8R A;  1OEM X;  1G4W R;  3N2A A;  1Q1M A;  5KA7 A;  1OHE A;  1JBW A;  2I3R A;  3QCM A;  2I4E A;  2PSZ A;  1ONZ A;  1Q6S A;  5K23 A;  2BGD A;  2NTA A;  4Y2E A;  4BUC A;  1MKP A;  4KI9 A;  1ZCL A;  1GQY A;  3F99 A;  4KYQ A;  2Y66 A;  1BZJ A;  1P15 A;  2Y2F A;  3D44 A;  2JJD A;  4GE6 A;  4RI5 A;  1OET A;  1PTU A;  2NT2 A;  3BLT A;  2H03 A;  1RXD A;  1ECV A;  2F00 A;  1LQF A;  2F6T A;  1PH0 A;  5KA1 A;  1U26 A;  3F81 A;  5LXQ B;  1D5R A;  2CFV A;  2ZMM A;  2I6I A;  5GTJ A;  4HJQ A;  2QBS A;  4ZN5 A;  2CNG A;  2QBR A;  2DXP A;  4QAH A;  1YTW A;  2F46 A;  4JMK A;  2CMA A;  2QDM A;  2GP0 A;  1E8C A;  5K9W A;  2NLK A;  1XXP A;  2VEU A;  3EAX A;  1UAG A;  4BPC A;  3B7O A;  4WU2 A;  1C88 A;  4R0T A;  2RF6 A;  1T49 A;  3I36 A;  3GXH A;  5K25 A;  2CNF A;  4WTY A;  4IKC A;  1W78 A;  4AZ1 A;  1T48 A;  2B4S A;  2XPC A;  3BRH A;  3QCH A;  2IMG A;  2H4K A;  1XBO A;  4RKK A;  3F9A A;  5IBS A;  1RPM A;  1J4X A;  4ZIY A;  1QZ0 A;  3M4U A;  2BZL A;  2QCJ A;  2I1Y A;  2NT7 A;  4RH5 A;  4MBB A;  2PI7 A;  5EHP A;  2Y1O A;  4RI4 A;  3HN7 A;  2QDP A;  4Y14 A;  2I6P A;  2VEX A;  4PVG A;  4H34 A;  4D3P A;  2CNH A;  4NND A;  1FPZ A;  1C83 A;  1G1H A;  3S3K A;  2UUO A;  2B49 A;  1A5Y A;  1C84 A;  3RO1 A;  3D42 A;  3O4T A;  3V0H A;  2Y67 A;  1OHC A;  2AZR A;  1PTV A;  1YTN A;  1PTT A;  3QCF A;  1Q6N A;  2I4G A;  3A5K A;  1YFO A;  1C87 A;  1GWZ A;  2GJT A;  3QCL A;  4NX8 A;  4GRZ A;  1G1F A;  3AWG A;  3QCK A;  4ZRT A;  3QKQ A;  4CVK A;  3I80 A;  2WJP A;  2VEW A;  3V0F A;  4HJP A;  2I3U A;  3OMH A;  1EEO A;  1OES A;  5BUG A;  3D1O A;  1XM2 A;  1BZC A;  1U25 A;  4GFV A;  2J17 A;  3RZ2 A;  3U96 A;  3MOW A;  2FJN A;  3S3E A;  3PS5 A;  2F6W A;  4JBC A;  2F70 A;  2VOS A;  1NZ7 A;  3OLR A;  4DGP A;  4YR8 B;  1G1G A;  2ESB A;  2X5O A;  1P31 A;  1EEN A;  3GXG A;  2I6O A;  3LJ8 A;  2CMC A;  3QCZ A;  1WAX A;  4JNB A;  2C7S A;  3V0J A;  2BGE A;  4J51 A;  4ICZ A;  2QDC A;  2GC6 A;  1BZH A;  1M3G A;  3O4S A;  2UAG A;  4NYH A;  2SHP A;  2F6V A;  1QXK A;  2FH7 A;  1FPR A;  3EU0 A;  2GC5 A;  2HXP A;  1OEU A;  2NV5 A;  2CNE A;  5KAC A;  1FQ1 A;  5KA2 A;  5KA8 A;  2Y68 A;  2JFH A;  2E0T A;  4GFU A;  3QCC A;  2C46 A;  1YPT A;  2XJA A;  4HRF A;  4QBW A;  4KYR A;  1G4U S;  5KA3 A;  4S0G A;  1L8G A;  1P3D A;  3D1Q A;  3EZZ A;  3ZM6 A;  1LAR A;  2G59 A;  1LYV A;  2HNQ A;  2Y96 A;  5I6V A;  1NO6 A;  1C85 A;  2OUD A;  3S3F A;  5BZZ A;  5KA9 A;  3MMJ A;  3QCG A;  4BUB A;  4WOH A;  5K24 A;  5BX1 A;  2NZ6 A; 
#chains in the Genus database with same CATH homology
 2H04 A;  2ZN7 A;  4BJO A;  2HNP A;  1X24 A;  3BLU A;  4GS0 A;  2I42 A;  4YAA A;  3ZM2 A;  1ZCK A;  3CM3 A;  2I5X A;  4D3R A;  3O3L A;  5BZX A;  1JF7 A;  5K22 A;  3I7Z A;  1ZZW A;  3SME A;  5EHR A;  1YGU A;  1Q6J A;  4QAP A;  2BIJ A;  2OZ5 A;  3F41 A;  3AWF A;  3EMU A;  2B4P A;  2QBP A;  3QKP A;  3EB1 A;  3O4U A;  2PA5 A;  4D3Q A;  1G7F A;  2HB1 A;  2I75 A;  1YGR A;  2VEV A;  1Q6P A;  4NWG A;  3D1H A;  5KAA A;  2B4O A;  1PA9 A;  3AWE A;  4ZI4 A;  5K9V A;  1JLN A;  2G6Z A;  3BM8 A;  4OHL A;  4R30 A;  5KA0 A;  2CM8 A;  3V0G A;  4GE5 A;  1ZC0 A;  2B3O A;  5MMZ B;  1OEO X;  2I6M A;  4GE2 A;  2B4U A;  1YN9 A;  2HVL A;  3ZMP A;  4B04 A;  1R6H A;  2F71 A;  5KA4 A;  1I9S A;  4RDD A;  3ZV2 A;  2BV5 A;  4OHE A;  4GRY A;  1XXV A;  2F6F A;  2VEY A;  1PYN A;  1YTS A;  3D9C A;  4NWF A;  5AWX A;  1PXH A;  3CWE A;  5KAD A;  4I8N A;  2CNI A;  1U24 A;  2H4G A;  5HDE A;  1ONY A;  2A3K A;  3QCD A;  1SUG A;  1GFY A;  1NNY A;  1V3A A;  3S3H A;  3ZM3 A;  2OOQ A;  3V0E A;  3QCN A;  2QBQ A;  1WRM A;  1NWE A;  4OHH A;  2QEP A;  4QUM A;  3MOZ A;  2P4D A;  3F9B A;  4WU3 A;  3H2X A;  2FJM A;  4H1O A;  4ERC A;  2J16 A;  1PTY A;  1XRI A;  2I4H A;  3S4E A;  4R0S A;  2HY3 A;  2QCT A;  5IBM A;  2M3V A;  3V0D A;  2CM7 A;  4QBE A;  4QUN A;  3N0A A;  1Q6T A;  2CMB A;  1AAX A;  1VHR A;  4OHD A;  3RGO A;  3ZM0 A;  2Q05 A;  4JMJ A;  2MBC A;  3QCE A;  2CJZ A;  2CM2 A;  2PBN A;  2YDU A;  1I57 A;  2CM3 A;  4RHG A;  4Z6B A;  1OHD A;  2F6Y A;  2HC2 A;  3S4O A;  3ZMQ A;  2A8B A;  2AHS A;  3QCB A;  2I6J A;  1I9T A;  2B07 A;  2OC3 A;  2PQ5 A;  1OEV A;  2PT0 A;  2R0B A;  4PYH A;  3SR9 A;  2H4V A;  1NL9 A;  2WGP A;  5M43 A;  1T4J A;  1YWF A;  1WCH A;  4DGX A;  1G7G A;  2J16 B;  4GWF A;  3QCI A;  3ZM1 A;  1KAK A;  3RGQ A;  1L8K A;  4OHI A;  2F6Z A;  2HC1 A;  2HCM A;  1C86 A;  2P6X A;  4TVV A;  1PA1 A;  3A5J A;  3NME A;  1KAV A;  2Q47 A;  5KAB A;  3V0I A;  1Q6M A;  3O5X A;  1YZ4 A;  2H02 A;  4RH9 A;  2GWO A;  1NWL A;  3QCJ A;  5J8R A;  1OEM X;  1G4W R;  1Q1M A;  5KA7 A;  1OHE A;  2I3R A;  3QCM A;  2I4E A;  2PSZ A;  1ONZ A;  1Q6S A;  5K23 A;  2BGD A;  2NTA A;  4Y2E A;  1MKP A;  4KI9 A;  1ZCL A;  3F99 A;  4KYQ A;  1BZJ A;  1P15 A;  2Y2F A;  3D44 A;  2JJD A;  4GE6 A;  4RI5 A;  1OET A;  1PTU A;  2NT2 A;  3BLT A;  2H03 A;  1RXD A;  1ECV A;  1LQF A;  2F6T A;  1PH0 A;  5KA1 A;  1U26 A;  3F81 A;  5LXQ B;  1D5R A;  2CFV A;  2ZMM A;  2I6I A;  5GTJ A;  4HJQ A;  2QBS A;  4ZN5 A;  2CNG A;  2QBR A;  2DXP A;  4QAH A;  1YTW A;  2F46 A;  4JMK A;  2CMA A;  2QDM A;  2GP0 A;  5K9W A;  2NLK A;  1XXP A;  2VEU A;  3EAX A;  4BPC A;  3B7O A;  4WU2 A;  1C88 A;  4R0T A;  2RF6 A;  1T49 A;  3I36 A;  3GXH A;  5K25 A;  2CNF A;  4WTY A;  4IKC A;  4AZ1 A;  1T48 A;  2B4S A;  3BRH A;  3QCH A;  2IMG A;  2H4K A;  1XBO A;  4RKK A;  3F9A A;  5IBS A;  1RPM A;  1J4X A;  1QZ0 A;  3M4U A;  2BZL A;  2QCJ A;  2I1Y A;  2NT7 A;  4RH5 A;  4MBB A;  2PI7 A;  5EHP A;  4RI4 A;  2QDP A;  4Y14 A;  2I6P A;  2VEX A;  4PVG A;  4H34 A;  4D3P A;  2CNH A;  4NND A;  1FPZ A;  1C83 A;  1G1H A;  3S3K A;  2B49 A;  1A5Y A;  1C84 A;  3RO1 A;  3D42 A;  3O4T A;  3V0H A;  1OHC A;  2AZR A;  1PTV A;  1YTN A;  1PTT A;  3QCF A;  1Q6N A;  2I4G A;  3A5K A;  1YFO A;  1C87 A;  1GWZ A;  2GJT A;  3QCL A;  4NX8 A;  4GRZ A;  1G1F A;  3AWG A;  3QCK A;  4ZRT A;  3QKQ A;  3I80 A;  2VEW A;  3V0F A;  4HJP A;  2I3U A;  3OMH A;  1EEO A;  1OES A;  5BUG A;  3D1O A;  1XM2 A;  1BZC A;  1U25 A;  4GFV A;  2J17 A;  3RZ2 A;  3U96 A;  3MOW A;  2FJN A;  3S3E A;  3PS5 A;  2F6W A;  4JBC A;  2F70 A;  1NZ7 A;  3OLR A;  4DGP A;  4YR8 B;  1G1G A;  2ESB A;  1EEN A;  3GXG A;  2I6O A;  3LJ8 A;  2CMC A;  1WAX A;  4JNB A;  2C7S A;  3V0J A;  2BGE A;  4J51 A;  4ICZ A;  2QDC A;  1BZH A;  1M3G A;  3O4S A;  4NYH A;  2SHP A;  2F6V A;  1QXK A;  2FH7 A;  1FPR A;  3EU0 A;  2HXP A;  1OEU A;  2NV5 A;  2CNE A;  5KAC A;  1FQ1 A;  5KA2 A;  5KA8 A;  2E0T A;  4GFU A;  3QCC A;  2C46 A;  1YPT A;  4HRF A;  4QBW A;  4KYR A;  1G4U S;  5KA3 A;  4S0G A;  1L8G A;  3D1Q A;  3EZZ A;  1LAR A;  2G59 A;  1LYV A;  2HNQ A;  2Y96 A;  5I6V A;  1NO6 A;  1C85 A;  2OUD A;  3S3F A;  5BZZ A;  5KA9 A;  3MMJ A;  3QCG A;  4WOH A;  5K24 A;  5BX1 A;  2NZ6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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