1NWLA

Crystal structure of the ptp1b complexed with sp7343-sp7964, a ptyr mimetic
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
283
structure length
283
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPSRVAKLPKNKNRNRYCDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTVGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of a New Phosphotyrosine Mimetic for PTP1B Using Breakaway Tethering
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords protein-tyrosine phosphatase, non-receptor type 1
total genus 96
structure length 283
sequence length 283
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2003-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1nwlA00
1OHEA 2P6XA 1R6HA 1PXHA 2VEUA 2B4OA 2QBQA 5K23A 4Y2EA 5EHPA 2CMCA 1M3GA 3CWEA 4NYHA 4GFUA 5KA7A 3MMJA 1ZC0A 3EB1A 2NT7A 5J8RA 1BZJA 3O3LA 2A8BA 2PSZA 2FH7A 2I6PA 2C7SA 1YTWA 4KI9A 3GXGA 1RPMA 3V0GA 5KA4A 5KAAA 1I9TA 3ZM3A 3F99A 1RXDA 2B4SA 3QCKA 5KA0A 1Q6PA 4DGXA 5K24A 5KACA 1I9SA 2H04A 3OLRA 2F46A 3D9CA 2C46A 2F6YA 3V0IA 2FJNA 1Q1MA 2I75A 3F81A 2Q05A 1PA9A 5BZXA 3QCJA 1G1HA 1OETA 2H02A 2QDCA 1JF7A 1VHRA 2CJZA 1MKPA 4GE5A 4Y14A 3I80A 3GXHA 3OMHA 1GFYA 1GWZA 3V0HA 1PTTA 3QCLA 2GJTA 4ZN5A 3QCDA 2HC1A 1ZCKA 2SHPA 5KA8A 1XBOA 3QCHA 5K25A 4HRFA 3U96A 4QBWA 4ZI4A 3MOZA 2BIJA 4OHIA 2CNFA 3EZZA 1NZ7A 4Z6BA 2B07A 1ECVA 2CM7A 2F6FA 2B4PA 2OOQA 1XRIA 2QDPA 3D44A 3I36A 2NLKA 4I8NA 5GTJA 1BZHA 1ZZWA 3F41A 1NWEA 2BV5A 4R0SA 3ZMPA 1U24A 3S3HA 2I6IA 2I6OA 4RH9A 1ONZA 5M43A 5K22A 4WOHA 5K9WA 2F70A 1WAXA 2Y2FA 5BZZA 2VEXA 1G4US 3D1HA 2AHSA 1C87A 4GRYA 4B04A 4JBCA 2HCMA 2I42A 3EAXA 3QCGA 2MBCA 1U26A 3B7OA 5KA2A 2J17A 3BRHA 4GRZA 4NX8A 4AZ1A 4OHHA 1T4JA 1YGRA 1J4XA 1ZCLA 2CNIA 4PVGA 4BPCA 4D3RA 1OEUA 4H1OA 2PBNA 4RKKA 5KA1A 4YR8B 1FPZA 1LARA 4RI4A 1FPRA 3CM3A 2PA5A 1G7FA 4NWFA 3SMEA 1QXKA 2Q47A 5I6VA 1EENA 1YZ4A 5HDEA 4HJQA 4RDDA 5IBMA 2CNGA 1X24A 3LJ8A 1Q6SA 2HC2A 2NTAA 5KA3A 2I4EA 4WU2A 2WGPA 3QCMA 4HJPA 3N0AA 1ONYA 5KABA 1QZ0A 2I6JA 2OUDA 2PT0A 4JMKA 5BX1A 4JMJA 2I1YA 2YDUA 1G7GA 3D1OA 3I7ZA 2OZ5A 1LYVA 4ZRTA 5EHRA 3RO1A 3SR9A 1PTYA 2E0TA 5AWXA 1OEOX 3ZM0A 2CMAA 2QDMA 3QKQA 2A3KA 3V0DA 1V3AA 2F6VA 4QUMA 2BGEA 3NMEA 4IKCA 2CM2A 5KA9A 1WCHA 3RZ2A 4ERCA 1C83A 2CNEA 4DGPA 3RGQA 4TVVA 4MBBA 4QBEA 1LQFA 5K9VA 2QEPA 3QCFA 4R0TA 4NWGA 2J16B 1WRMA 2R0BA 1L8GA 1I57A 4ICZA 1YTNA 2AZRA 4H34A 1OHDA 5MMZB 2CFVA 4KYRA 4S0GA 1YPTA 3O4SA 1T48A 1SUGA 2I6MA 4RHGA 3V0EA 3F9BA 4J51A 3QKPA 2VEYA 2H4KA 4BJOA 1G4WR 3ZMQA 5LXQB 1XXVA 2ESBA 1PTVA 1A5YA 2QBPA 4QUNA 2I4GA 2QCJA 4D3QA 1YWFA 1BZCA 3QCIA 1G1GA 1PYNA 3BLTA 1Q6TA 3O4UA 4GS0A 3AWFA 1C86A 2CNHA 2QBSA 3A5KA 4D3PA 3AWEA 1EEOA 3O5XA 2RF6A 4QAPA 1OHCA 1T49A 1XXPA 2BZLA 1NO6A 4GE2A 4YAAA 3F9AA 2VEWA 3S3EA 1C85A 2G59A 4GFVA 1NL9A 4R30A 2VEVA 2P4DA 3ZM1A 1C88A 2ZMMA 3S4EA 2Y96A 2M3VA 3S3KA 1YGUA 2H03A 3V0JA 1U25A 2BGDA 1NNYA 4GE6A 2HVLA 1OEVA 3EU0A 1D5RA 4OHLA 1Q6MA 5BUGA 2GP0A 2F71A 2J16A 2QCTA 4GWFA 4OHEA 3QCEA 1YN9A 2F6ZA 3ZM2A 4NNDA 3H2XA 1P15A 1YTSA 3EMUA 2HNPA 2CM8A 3D42A 4RH5A 1C84A 1G1FA 1L8KA 1NWLA 1AAXA 2HB1A 3M4UA 1JLNA 1KAVA 1OEMX 5KADA 2F6TA 4WTYA 2JJDA 1OESA 3BLUA 2PI7A 2HNQA 4RI5A 2NZ6A 2OC3A 3D1QA 3V0FA 2I4HA 2CM3A 2IMGA 3QCCA 4OHDA 2CMBA 2GWOA 2PQ5A 2NT2A 1Q6JA 1XM2A 3ZV2A 1YFOA 3O4TA 3PS5A 2I3RA 2H4GA 3S4OA 2I5XA 2HXPA 3QCNA 2QBRA 3BM8A 2B3OA 1KAKA 3AWGA 4KYQA 3S3FA 2B4UA 2HY3A 1PA1A 1PTUA 3A5JA 2F6WA 4JNBA 1PH0A 3MOWA 2H4VA 2G6ZA 1Q6NA 5IBSA 4QAHA 2ZN7A 1FQ1A 4PYHA 3QCBA 2NV5A 2B49A 2I3UA 4WU3A 2DXPA 2FJMA 3RGOA
chains in the Genus database with same CATH superfamily
3NRSA 1OHEA 2P6XA 1R6HA 1PXHA 2VEUA 3ZL8A 2B4OA 2QBQA 1JBWA 5K23A 4Y2EA 5EHPA 2CMCA 1M3GA 3CWEA 4NYHA 4BUBA 4GFUA 5KA7A 3MMJA 1ZC0A 3EB1A 2NT7A 1E0DA 5J8RA 2Y1OA 1BZJA 2A8BA 2PSZA 3O3LA 2FH7A 2I6PA 2C7SA 1YTWA 4KI9A 3GXGA 1RPMA 3V0GA 5KA4A 5KAAA 1I9TA 3ZM3A 3F99A 1RXDA 2B4SA 3QCZA 3QCKA 5KA0A 1Q6PA 2JFHA 4DGXA 5K24A 5KACA 1I9SA 2H04A 3OLRA 2F46A 2JFFA 3D9CA 2C46A 2F6YA 3V0IA 2VOSA 2FJNA 1Q1MA 2I75A 3F81A 2Q05A 1PA9A 5BZXA 3QCJA 1G1HA 1OETA 2H02A 2QDCA 1JF7A 1VHRA 2CJZA 3N2AA 1MKPA 4GE5A 4Y14A 3I80A 2XJAA 3GXHA 1W7KA 1GFYA 1GWZA 3OMHA 3V0HA 1PTTA 3QCLA 2GJTA 4ZN5A 3QCDA 2HC1A 1ZCKA 2SHPA 3MVNA 1P3DA 5KA8A 4HV4A 1XBOA 3QCHA 5K25A 4HRFA 2VORA 3U96A 4QBWA 4ZI4A 3MOZA 4CVMA 2BIJA 4OHIA 2CNFA 3EZZA 1NZ7A 4Z6BA 1E8CA 2B07A 1ECVA 2CM7A 2F6FA 2B4PA 2OOQA 1XRIA 2QDPA 3D44A 3I36A 5A5FA 2NLKA 4I8NA 5GTJA 1BZHA 1ZZWA 3F41A 1NWEA 2BV5A 4R0SA 3ZMPA 1U24A 3ZM5A 3S3HA 2I6IA 2I6OA 4RH9A 1ONZA 5M43A 5K22A 4WOHA 5K9WA 2F70A 1WAXA 2Y2FA 5BZZA 2VEXA 1G4US 3D1HA 2AHSA 1C87A 4GRYA 4B04A 1GQQA 4JBCA 2HCMA 2I42A 3EAXA 3QCGA 2MBCA 1U26A 3B7OA 5KA2A 2J17A 3BRHA 4QF5A 4GRZA 5A5EA 2GC6A 4NX8A 4AZ1A 4OHHA 1GQYA 1T4JA 1YGRA 1J4XA 1ZCLA 2CNIA 4PVGA 4ZIYA 4BPCA 4D3RA 1OEUA 2AM1A 4H1OA 2PBNA 4RKKA 5KA1A 2GCBA 4YR8B 1FPZA 1LARA 4RI4A 4CVLA 1GG4A 1FPRA 3CM3A 2PA5A 1G7FA 4NWFA 3SMEA 1QXKA 2Q47A 5I6VA 4C13A 1EENA 1YZ4A 5HDEA 4HJQA 4RDDA 5IBMA 2CNGA 1X24A 3LJ8A 1Q6SA 2HC2A 2NTAA 5KA3A 2I4EA 4WU2A 2WGPA 3QCMA 4HJPA 3N0AA 1ONYA 5KABA 1QZ0A 2I6JA 2OUDA 2PT0A 2Y68A 4JMKA 5BX1A 4JMJA 2I1YA 2YDUA 1G7GA 3D1OA 3I7ZA 2OZ5A 1LYVA 4ZRTA 5EHRA 3RO1A 3SR9A 1PTYA 2E0TA 5AWXA 2F00A 2WTZA 1OEOX 3ZM0A 2CMAA 2QDMA 3QKQA 2A3KA 3V0DA 1V3AA 2F6VA 4QUMA 2BGEA 3NMEA 4IKCA 1O5ZA 2CM2A 2WJPA 5KA9A 1WCHA 3RZ2A 4ERCA 1C83A 2CNEA 4DGPA 2UAGA 3RGQA 4TVVA 4MBBA 4QBEA 1LQFA 5K9VA 2QEPA 3QCFA 2JFGA 4R0TA 4NWGA 2J16B 1WRMA 2R0BA 2XPCA 1L8GA 1I57A 4ICZA 1YTNA 2AZRA 4H34A 1OHDA 5MMZB 2CFVA 4KYRA 4S0GA 1YPTA 1W78A 3O4SA 1T48A 1SUGA 4QDIA 2I6MA 4RHGA 3V0EA 3F9BA 4J51A 1FGSA 1EEHA 3QKPA 2VEYA 2H4KA 4BJOA 1G4WR 3HN7A 2GCAA 3ZMQA 1UAGA 5LXQB 1XXVA 2ESBA 1PTVA 1A5YA 2QBPA 4QUNA 2I4GA 2QCJA 3LK7A 4D3QA 1YWFA 1BZCA 3QCIA 1G1GA 1PYNA 3BLTA 1Q6TA 2UUOA 3O4UA 4GS0A 3AWFA 1C86A 2CNHA 2QBSA 3A5KA 4D3PA 3AWEA 1EEOA 3O5XA 2RF6A 4QAPA 1OHCA 1T49A 1XXPA 2BZLA 1NO6A 4GE2A 4CVKA 4YAAA 3F9AA 2VEWA 3S3EA 1J6UA 1C85A 2G59A 4GFVA 1NL9A 4R30A 2VEVA 2P4DA 3ZM1A 1C88A 2ZMMA 3S4EA 2Y96A 2M3VA 3S3KA 1YGUA 2H03A 4UAGA 3V0JA 1U25A 2BGDA 1NNYA 4GE6A 2HVLA 1OEVA 3EU0A 1D5RA 4OHLA 1Q6MA 5BUGA 2GP0A 2F71A 2J16A 2QCTA 4GWFA 4OHEA 3QCEA 1YN9A 2AM2A 2F6ZA 3ZM2A 4NNDA 3H2XA 1P15A 1JBVA 1YTSA 3EMUA 2HNPA 2Y66A 2CM8A 3D42A 4RH5A 1C84A 1G1FA 1L8KA 1NWLA 1AAXA 2HB1A 3M4UA 1JLNA 1KAVA 1OEMX 5KADA 2F6TA 4WTYA 2JJDA 1OESA 3BLUA 2PI7A 3UAGA 2HNQA 4RI5A 2NZ6A 2OC3A 3D1QA 3V0FA 2I4HA 2CM3A 2IMGA 3QCCA 4OHDA 2CMBA 2GWOA 3ZM6A 2PQ5A 2NT2A 1Q6JA 1XM2A 3PYZA 3ZV2A 1YFOA 3O4TA 3PS5A 2I3RA 2H4GA 3S4OA 2I5XA 2HXPA 3QCNA 3BM8A 2QBRA 2B3OA 1KAKA 3AWGA 4KYQA 3S3FA 2VTDA 2UUPA 2B4UA 2HY3A 1PA1A 1PTUA 3A5JA 2X5OA 2F6WA 4JNBA 4BUCA 1P31A 1PH0A 3MOWA 2GC5A 2H4VA 2G6ZA 1Q6NA 5IBSA 4C12A 4QAHA 2ZN7A 1FQ1A 4PYHA 2Y67A 3QCBA 2NV5A 2B49A 2I3UA 2VTEA 4WU3A 2DXPA 2FJMA 3RGOA
chains in the Genus database with same CATH topology
1OHEA 2P6XA 1R6HA 1PXHA 2VEUA 2B4OA 2QBQA 5K23A 4Y2EA 5EHPA 2CMCA 1M3GA 3CWEA 4NYHA 4GFUA 5KA7A 3MMJA 1ZC0A 3EB1A 2NT7A 5J8RA 1BZJA 3O3LA 2A8BA 2PSZA 2FH7A 2I6PA 2C7SA 1YTWA 4KI9A 3GXGA 1RPMA 3V0GA 5KA4A 5KAAA 1I9TA 3ZM3A 3F99A 1RXDA 2B4SA 3QCKA 5KA0A 1Q6PA 4DGXA 5K24A 5KACA 1I9SA 2H04A 3OLRA 2F46A 3D9CA 2C46A 2F6YA 3V0IA 2FJNA 1Q1MA 2I75A 3F81A 2Q05A 1PA9A 5BZXA 3QCJA 1G1HA 1OETA 2H02A 2QDCA 1JF7A 1VHRA 2CJZA 1MKPA 4GE5A 4Y14A 3I80A 3GXHA 3OMHA 1GFYA 1GWZA 3V0HA 1PTTA 3QCLA 2GJTA 4ZN5A 3QCDA 2HC1A 1ZCKA 2SHPA 5KA8A 1XBOA 3QCHA 5K25A 4HRFA 3U96A 4QBWA 4ZI4A 3MOZA 2BIJA 4OHIA 2CNFA 3EZZA 1NZ7A 4Z6BA 2B07A 1ECVA 2CM7A 2F6FA 2B4PA 2OOQA 1XRIA 2QDPA 3D44A 3I36A 2NLKA 4I8NA 5GTJA 1BZHA 1ZZWA 3F41A 1NWEA 2BV5A 4R0SA 3ZMPA 1U24A 3S3HA 2I6IA 2I6OA 4RH9A 1ONZA 5M43A 5K22A 4WOHA 5K9WA 2F70A 1WAXA 2Y2FA 5BZZA 2VEXA 1G4US 3D1HA 2AHSA 1C87A 4GRYA 4B04A 4JBCA 2HCMA 2I42A 3EAXA 3QCGA 2MBCA 1U26A 3B7OA 5KA2A 2J17A 3BRHA 4GRZA 4NX8A 4AZ1A 4OHHA 1T4JA 1YGRA 1J4XA 1ZCLA 2CNIA 4PVGA 4BPCA 4D3RA 1OEUA 4H1OA 2PBNA 4RKKA 5KA1A 4YR8B 1FPZA 1LARA 4RI4A 1FPRA 3CM3A 2PA5A 1G7FA 4NWFA 3SMEA 1QXKA 2Q47A 5I6VA 1EENA 1YZ4A 5HDEA 4HJQA 4RDDA 5IBMA 2CNGA 1X24A 3LJ8A 1Q6SA 2HC2A 2NTAA 5KA3A 2I4EA 4WU2A 2WGPA 3QCMA 4HJPA 3N0AA 1ONYA 5KABA 1QZ0A 2I6JA 2OUDA 2PT0A 4JMKA 5BX1A 4JMJA 2I1YA 2YDUA 1G7GA 3D1OA 3I7ZA 2OZ5A 1LYVA 4ZRTA 5EHRA 3RO1A 3SR9A 1PTYA 2E0TA 5AWXA 1OEOX 3ZM0A 2CMAA 2QDMA 3QKQA 2A3KA 3V0DA 1V3AA 2F6VA 4QUMA 2BGEA 3NMEA 4IKCA 2CM2A 5KA9A 1WCHA 3RZ2A 4ERCA 1C83A 2CNEA 4DGPA 3RGQA 4TVVA 4MBBA 4QBEA 1LQFA 5K9VA 2QEPA 3QCFA 4R0TA 4NWGA 2J16B 1WRMA 2R0BA 1L8GA 1I57A 4ICZA 1YTNA 2AZRA 4H34A 1OHDA 5MMZB 2CFVA 4KYRA 4S0GA 1YPTA 3O4SA 1T48A 1SUGA 2I6MA 4RHGA 3V0EA 3F9BA 4J51A 3QKPA 2VEYA 2H4KA 4BJOA 1G4WR 3ZMQA 5LXQB 1XXVA 2ESBA 1PTVA 1A5YA 2QBPA 4QUNA 2I4GA 2QCJA 4D3QA 1YWFA 1BZCA 3QCIA 1G1GA 1PYNA 3BLTA 1Q6TA 3O4UA 4GS0A 3AWFA 1C86A 2CNHA 2QBSA 3A5KA 4D3PA 3AWEA 1EEOA 3O5XA 2RF6A 4QAPA 1OHCA 1T49A 1XXPA 2BZLA 1NO6A 4GE2A 4YAAA 3F9AA 2VEWA 3S3EA 1C85A 2G59A 4GFVA 1NL9A 4R30A 2VEVA 2P4DA 3ZM1A 1C88A 2ZMMA 3S4EA 2Y96A 2M3VA 3S3KA 1YGUA 2H03A 3V0JA 1U25A 2BGDA 1NNYA 4GE6A 2HVLA 1OEVA 3EU0A 1D5RA 4OHLA 1Q6MA 5BUGA 2GP0A 2F71A 2J16A 2QCTA 4GWFA 4OHEA 3QCEA 1YN9A 2F6ZA 3ZM2A 4NNDA 3H2XA 1P15A 1YTSA 3EMUA 2HNPA 2CM8A 3D42A 4RH5A 1C84A 1G1FA 1L8KA 1NWLA 1AAXA 2HB1A 3M4UA 1JLNA 1KAVA 1OEMX 5KADA 2F6TA 4WTYA 2JJDA 1OESA 3BLUA 2PI7A 2HNQA 4RI5A 2NZ6A 2OC3A 3D1QA 3V0FA 2I4HA 2CM3A 2IMGA 3QCCA 4OHDA 2CMBA 2GWOA 2PQ5A 2NT2A 1Q6JA 1XM2A 3ZV2A 1YFOA 3O4TA 3PS5A 2I3RA 2H4GA 3S4OA 2I5XA 2HXPA 3QCNA 2QBRA 3BM8A 2B3OA 1KAKA 3AWGA 4KYQA 3S3FA 2B4UA 2HY3A 1PA1A 1PTUA 3A5JA 2F6WA 4JNBA 1PH0A 3MOWA 2H4VA 2G6ZA 1Q6NA 5IBSA 4QAHA 2ZN7A 1FQ1A 4PYHA 3QCBA 2NV5A 2B49A 2I3UA 4WU3A 2DXPA 2FJMA 3RGOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OHE A;  2P6X A;  1R6H A;  1PXH A;  2VEU A;  2B4O A;  2QBQ A;  5K23 A;  4Y2E A;  5EHP A;  2CMC A;  1M3G A;  3CWE A;  4NYH A;  4GFU A;  5KA7 A;  3MMJ A;  1ZC0 A;  3EB1 A;  2NT7 A;  5J8R A;  1BZJ A;  3O3L A;  2A8B A;  2PSZ A;  2FH7 A;  2I6P A;  2C7S A;  1YTW A;  4KI9 A;  3GXG A;  1RPM A;  3V0G A;  5KA4 A;  5KAA A;  1I9T A;  3ZM3 A;  3F99 A;  1RXD A;  2B4S A;  3QCK A;  5KA0 A;  1Q6P A;  4DGX A;  5K24 A;  5KAC A;  1I9S A;  2H04 A;  3OLR A;  2F46 A;  3D9C A;  2C46 A;  2F6Y A;  3V0I A;  2FJN A;  1Q1M A;  2I75 A;  3F81 A;  2Q05 A;  1PA9 A;  5BZX A;  3QCJ A;  1G1H A;  1OET A;  2H02 A;  2QDC A;  1JF7 A;  1VHR A;  2CJZ A;  1MKP A;  4GE5 A;  4Y14 A;  3I80 A;  3GXH A;  3OMH A;  1GFY A;  1GWZ A;  3V0H A;  1PTT A;  3QCL A;  2GJT A;  4ZN5 A;  3QCD A;  2HC1 A;  1ZCK A;  2SHP A;  5KA8 A;  1XBO A;  3QCH A;  5K25 A;  4HRF A;  3U96 A;  4QBW A;  4ZI4 A;  3MOZ A;  2BIJ A;  4OHI A;  2CNF A;  3EZZ A;  1NZ7 A;  4Z6B A;  2B07 A;  1ECV A;  2CM7 A;  2F6F A;  2B4P A;  2OOQ A;  1XRI A;  2QDP A;  3D44 A;  3I36 A;  2NLK A;  4I8N A;  5GTJ A;  1BZH A;  1ZZW A;  3F41 A;  1NWE A;  2BV5 A;  4R0S A;  3ZMP A;  1U24 A;  3S3H A;  2I6I A;  2I6O A;  4RH9 A;  1ONZ A;  5M43 A;  5K22 A;  4WOH A;  5K9W A;  2F70 A;  1WAX A;  2Y2F A;  5BZZ A;  2VEX A;  1G4U S;  3D1H A;  2AHS A;  1C87 A;  4GRY A;  4B04 A;  4JBC A;  2HCM A;  2I42 A;  3EAX A;  3QCG A;  2MBC A;  1U26 A;  3B7O A;  5KA2 A;  2J17 A;  3BRH A;  4GRZ A;  4NX8 A;  4AZ1 A;  4OHH A;  1T4J A;  1YGR A;  1J4X A;  1ZCL A;  2CNI A;  4PVG A;  4BPC A;  4D3R A;  1OEU A;  4H1O A;  2PBN A;  4RKK A;  5KA1 A;  4YR8 B;  1FPZ A;  1LAR A;  4RI4 A;  1FPR A;  3CM3 A;  2PA5 A;  1G7F A;  4NWF A;  3SME A;  1QXK A;  2Q47 A;  5I6V A;  1EEN A;  1YZ4 A;  5HDE A;  4HJQ A;  4RDD A;  5IBM A;  2CNG A;  1X24 A;  3LJ8 A;  1Q6S A;  2HC2 A;  2NTA A;  5KA3 A;  2I4E A;  4WU2 A;  2WGP A;  3QCM A;  4HJP A;  3N0A A;  1ONY A;  5KAB A;  1QZ0 A;  2I6J A;  2OUD A;  2PT0 A;  4JMK A;  5BX1 A;  4JMJ A;  2I1Y A;  2YDU A;  1G7G A;  3D1O A;  3I7Z A;  2OZ5 A;  1LYV A;  4ZRT A;  5EHR A;  3RO1 A;  3SR9 A;  1PTY A;  2E0T A;  5AWX A;  1OEO X;  3ZM0 A;  2CMA A;  2QDM A;  3QKQ A;  2A3K A;  3V0D A;  1V3A A;  2F6V A;  4QUM A;  2BGE A;  3NME A;  4IKC A;  2CM2 A;  5KA9 A;  1WCH A;  3RZ2 A;  4ERC A;  1C83 A;  2CNE A;  4DGP A;  3RGQ A;  4TVV A;  4MBB A;  4QBE A;  1LQF A;  5K9V A;  2QEP A;  3QCF A;  4R0T A;  4NWG A;  2J16 B;  1WRM A;  2R0B A;  1L8G A;  1I57 A;  4ICZ A;  1YTN A;  2AZR A;  4H34 A;  1OHD A;  5MMZ B;  2CFV A;  4KYR A;  4S0G A;  1YPT A;  3O4S A;  1T48 A;  1SUG A;  2I6M A;  4RHG A;  3V0E A;  3F9B A;  4J51 A;  3QKP A;  2VEY A;  2H4K A;  4BJO A;  1G4W R;  3ZMQ A;  5LXQ B;  1XXV A;  2ESB A;  1PTV A;  1A5Y A;  2QBP A;  4QUN A;  2I4G A;  2QCJ A;  4D3Q A;  1YWF A;  1BZC A;  3QCI A;  1G1G A;  1PYN A;  3BLT A;  1Q6T A;  3O4U A;  4GS0 A;  3AWF A;  1C86 A;  2CNH A;  2QBS A;  3A5K A;  4D3P A;  3AWE A;  1EEO A;  3O5X A;  2RF6 A;  4QAP A;  1OHC A;  1T49 A;  1XXP A;  2BZL A;  1NO6 A;  4GE2 A;  4YAA A;  3F9A A;  2VEW A;  3S3E A;  1C85 A;  2G59 A;  4GFV A;  1NL9 A;  4R30 A;  2VEV A;  2P4D A;  3ZM1 A;  1C88 A;  2ZMM A;  3S4E A;  2Y96 A;  2M3V A;  3S3K A;  1YGU A;  2H03 A;  3V0J A;  1U25 A;  2BGD A;  1NNY A;  4GE6 A;  2HVL A;  1OEV A;  3EU0 A;  1D5R A;  4OHL A;  1Q6M A;  5BUG A;  2GP0 A;  2F71 A;  2J16 A;  2QCT A;  4GWF A;  4OHE A;  3QCE A;  1YN9 A;  2F6Z A;  3ZM2 A;  4NND A;  3H2X A;  1P15 A;  1YTS A;  3EMU A;  2HNP A;  2CM8 A;  3D42 A;  4RH5 A;  1C84 A;  1G1F A;  1L8K A;  1NWL A;  1AAX A;  2HB1 A;  3M4U A;  1JLN A;  1KAV A;  1OEM X;  5KAD A;  2F6T A;  4WTY A;  2JJD A;  1OES A;  3BLU A;  2PI7 A;  2HNQ A;  4RI5 A;  2NZ6 A;  2OC3 A;  3D1Q A;  3V0F A;  2I4H A;  2CM3 A;  2IMG A;  3QCC A;  4OHD A;  2CMB A;  2GWO A;  2PQ5 A;  2NT2 A;  1Q6J A;  1XM2 A;  3ZV2 A;  1YFO A;  3O4T A;  3PS5 A;  2I3R A;  2H4G A;  3S4O A;  2I5X A;  2HXP A;  3QCN A;  2QBR A;  3BM8 A;  2B3O A;  1KAK A;  3AWG A;  4KYQ A;  3S3F A;  2B4U A;  2HY3 A;  1PA1 A;  1PTU A;  3A5J A;  2F6W A;  4JNB A;  1PH0 A;  3MOW A;  2H4V A;  2G6Z A;  1Q6N A;  5IBS A;  4QAH A;  2ZN7 A;  1FQ1 A;  4PYH A;  3QCB A;  2NV5 A;  2B49 A;  2I3U A;  4WU3 A;  2DXP A;  2FJM A;  3RGO A; 
#chains in the Genus database with same CATH topology
 3NRS A;  1OHE A;  2P6X A;  1R6H A;  1PXH A;  2VEU A;  3ZL8 A;  2B4O A;  2QBQ A;  1JBW A;  5K23 A;  4Y2E A;  5EHP A;  2CMC A;  1M3G A;  3CWE A;  4NYH A;  4BUB A;  4GFU A;  5KA7 A;  3MMJ A;  1ZC0 A;  3EB1 A;  2NT7 A;  1E0D A;  5J8R A;  2Y1O A;  1BZJ A;  2A8B A;  2PSZ A;  3O3L A;  2FH7 A;  2I6P A;  2C7S A;  1YTW A;  4KI9 A;  3GXG A;  1RPM A;  3V0G A;  5KA4 A;  5KAA A;  1I9T A;  3ZM3 A;  3F99 A;  1RXD A;  2B4S A;  3QCZ A;  3QCK A;  5KA0 A;  1Q6P A;  2JFH A;  4DGX A;  5K24 A;  5KAC A;  1I9S A;  2H04 A;  3OLR A;  2F46 A;  2JFF A;  3D9C A;  2C46 A;  2F6Y A;  3V0I A;  2VOS A;  2FJN A;  1Q1M A;  2I75 A;  3F81 A;  2Q05 A;  1PA9 A;  5BZX A;  3QCJ A;  1G1H A;  1OET A;  2H02 A;  2QDC A;  1JF7 A;  1VHR A;  2CJZ A;  3N2A A;  1MKP A;  4GE5 A;  4Y14 A;  3I80 A;  2XJA A;  3GXH A;  1W7K A;  1GFY A;  1GWZ A;  3OMH A;  3V0H A;  1PTT A;  3QCL A;  2GJT A;  4ZN5 A;  3QCD A;  2HC1 A;  1ZCK A;  2SHP A;  3MVN A;  1P3D A;  5KA8 A;  4HV4 A;  1XBO A;  3QCH A;  5K25 A;  4HRF A;  2VOR A;  3U96 A;  4QBW A;  4ZI4 A;  3MOZ A;  4CVM A;  2BIJ A;  4OHI A;  2CNF A;  3EZZ A;  1NZ7 A;  4Z6B A;  1E8C A;  2B07 A;  1ECV A;  2CM7 A;  2F6F A;  2B4P A;  2OOQ A;  1XRI A;  2QDP A;  3D44 A;  3I36 A;  5A5F A;  2NLK A;  4I8N A;  5GTJ A;  1BZH A;  1ZZW A;  3F41 A;  1NWE A;  2BV5 A;  4R0S A;  3ZMP A;  1U24 A;  3ZM5 A;  3S3H A;  2I6I A;  2I6O A;  4RH9 A;  1ONZ A;  5M43 A;  5K22 A;  4WOH A;  5K9W A;  2F70 A;  1WAX A;  2Y2F A;  5BZZ A;  2VEX A;  1G4U S;  3D1H A;  2AHS A;  1C87 A;  4GRY A;  4B04 A;  1GQQ A;  4JBC A;  2HCM A;  2I42 A;  3EAX A;  3QCG A;  2MBC A;  1U26 A;  3B7O A;  5KA2 A;  2J17 A;  3BRH A;  4QF5 A;  4GRZ A;  5A5E A;  2GC6 A;  4NX8 A;  4AZ1 A;  4OHH A;  1GQY A;  1T4J A;  1YGR A;  1J4X A;  1ZCL A;  2CNI A;  4PVG A;  4ZIY A;  4BPC A;  4D3R A;  1OEU A;  2AM1 A;  4H1O A;  2PBN A;  4RKK A;  5KA1 A;  2GCB A;  4YR8 B;  1FPZ A;  1LAR A;  4RI4 A;  4CVL A;  1GG4 A;  1FPR A;  3CM3 A;  2PA5 A;  1G7F A;  4NWF A;  3SME A;  1QXK A;  2Q47 A;  5I6V A;  4C13 A;  1EEN A;  1YZ4 A;  5HDE A;  4HJQ A;  4RDD A;  5IBM A;  2CNG A;  1X24 A;  3LJ8 A;  1Q6S A;  2HC2 A;  2NTA A;  5KA3 A;  2I4E A;  4WU2 A;  2WGP A;  3QCM A;  4HJP A;  3N0A A;  1ONY A;  5KAB A;  1QZ0 A;  2I6J A;  2OUD A;  2PT0 A;  2Y68 A;  4JMK A;  5BX1 A;  4JMJ A;  2I1Y A;  2YDU A;  1G7G A;  3D1O A;  3I7Z A;  2OZ5 A;  1LYV A;  4ZRT A;  5EHR A;  3RO1 A;  3SR9 A;  1PTY A;  2E0T A;  5AWX A;  2F00 A;  2WTZ A;  1OEO X;  3ZM0 A;  2CMA A;  2QDM A;  3QKQ A;  2A3K A;  3V0D A;  1V3A A;  2F6V A;  4QUM A;  2BGE A;  3NME A;  4IKC A;  1O5Z A;  2CM2 A;  2WJP A;  5KA9 A;  1WCH A;  3RZ2 A;  4ERC A;  1C83 A;  2CNE A;  4DGP A;  2UAG A;  3RGQ A;  4TVV A;  4MBB A;  4QBE A;  1LQF A;  5K9V A;  2QEP A;  3QCF A;  2JFG A;  4R0T A;  4NWG A;  2J16 B;  1WRM A;  2R0B A;  2XPC A;  1L8G A;  1I57 A;  4ICZ A;  1YTN A;  2AZR A;  4H34 A;  1OHD A;  5MMZ B;  2CFV A;  4KYR A;  4S0G A;  1YPT A;  1W78 A;  3O4S A;  1T48 A;  1SUG A;  4QDI A;  2I6M A;  4RHG A;  3V0E A;  3F9B A;  4J51 A;  1FGS A;  1EEH A;  3QKP A;  2VEY A;  2H4K A;  4BJO A;  1G4W R;  3HN7 A;  2GCA A;  3ZMQ A;  1UAG A;  5LXQ B;  1XXV A;  2ESB A;  1PTV A;  1A5Y A;  2QBP A;  4QUN A;  2I4G A;  2QCJ A;  3LK7 A;  4D3Q A;  1YWF A;  1BZC A;  3QCI A;  1G1G A;  1PYN A;  3BLT A;  1Q6T A;  2UUO A;  3O4U A;  4GS0 A;  3AWF A;  1C86 A;  2CNH A;  2QBS A;  3A5K A;  4D3P A;  3AWE A;  1EEO A;  3O5X A;  2RF6 A;  4QAP A;  1OHC A;  1T49 A;  1XXP A;  2BZL A;  1NO6 A;  4GE2 A;  4CVK A;  4YAA A;  3F9A A;  2VEW A;  3S3E A;  1J6U A;  1C85 A;  2G59 A;  4GFV A;  1NL9 A;  4R30 A;  2VEV A;  2P4D A;  3ZM1 A;  1C88 A;  2ZMM A;  3S4E A;  2Y96 A;  2M3V A;  3S3K A;  1YGU A;  2H03 A;  4UAG A;  3V0J A;  1U25 A;  2BGD A;  1NNY A;  4GE6 A;  2HVL A;  1OEV A;  3EU0 A;  1D5R A;  4OHL A;  1Q6M A;  5BUG A;  2GP0 A;  2F71 A;  2J16 A;  2QCT A;  4GWF A;  4OHE A;  3QCE A;  1YN9 A;  2AM2 A;  2F6Z A;  3ZM2 A;  4NND A;  3H2X A;  1P15 A;  1JBV A;  1YTS A;  3EMU A;  2HNP A;  2Y66 A;  2CM8 A;  3D42 A;  4RH5 A;  1C84 A;  1G1F A;  1L8K A;  1NWL A;  1AAX A;  2HB1 A;  3M4U A;  1JLN A;  1KAV A;  1OEM X;  5KAD A;  2F6T A;  4WTY A;  2JJD A;  1OES A;  3BLU A;  2PI7 A;  3UAG A;  2HNQ A;  4RI5 A;  2NZ6 A;  2OC3 A;  3D1Q A;  3V0F A;  2I4H A;  2CM3 A;  2IMG A;  3QCC A;  4OHD A;  2CMB A;  2GWO A;  3ZM6 A;  2PQ5 A;  2NT2 A;  1Q6J A;  1XM2 A;  3PYZ A;  3ZV2 A;  1YFO A;  3O4T A;  3PS5 A;  2I3R A;  2H4G A;  3S4O A;  2I5X A;  2HXP A;  3QCN A;  3BM8 A;  2QBR A;  2B3O A;  1KAK A;  3AWG A;  4KYQ A;  3S3F A;  2VTD A;  2UUP A;  2B4U A;  2HY3 A;  1PA1 A;  1PTU A;  3A5J A;  2X5O A;  2F6W A;  4JNB A;  4BUC A;  1P31 A;  1PH0 A;  3MOW A;  2GC5 A;  2H4V A;  2G6Z A;  1Q6N A;  5IBS A;  4C12 A;  4QAH A;  2ZN7 A;  1FQ1 A;  4PYH A;  2Y67 A;  3QCB A;  2NV5 A;  2B49 A;  2I3U A;  2VTE A;  4WU3 A;  2DXP A;  2FJM A;  3RGO A; 
#chains in the Genus database with same CATH homology
 1OHE A;  2P6X A;  1R6H A;  1PXH A;  2VEU A;  2B4O A;  2QBQ A;  5K23 A;  4Y2E A;  5EHP A;  2CMC A;  1M3G A;  3CWE A;  4NYH A;  4GFU A;  5KA7 A;  3MMJ A;  1ZC0 A;  3EB1 A;  2NT7 A;  5J8R A;  1BZJ A;  3O3L A;  2A8B A;  2PSZ A;  2FH7 A;  2I6P A;  2C7S A;  1YTW A;  4KI9 A;  3GXG A;  1RPM A;  3V0G A;  5KA4 A;  5KAA A;  1I9T A;  3ZM3 A;  3F99 A;  1RXD A;  2B4S A;  3QCK A;  5KA0 A;  1Q6P A;  4DGX A;  5K24 A;  5KAC A;  1I9S A;  2H04 A;  3OLR A;  2F46 A;  3D9C A;  2C46 A;  2F6Y A;  3V0I A;  2FJN A;  1Q1M A;  2I75 A;  3F81 A;  2Q05 A;  1PA9 A;  5BZX A;  3QCJ A;  1G1H A;  1OET A;  2H02 A;  2QDC A;  1JF7 A;  1VHR A;  2CJZ A;  1MKP A;  4GE5 A;  4Y14 A;  3I80 A;  3GXH A;  3OMH A;  1GFY A;  1GWZ A;  3V0H A;  1PTT A;  3QCL A;  2GJT A;  4ZN5 A;  3QCD A;  2HC1 A;  1ZCK A;  2SHP A;  5KA8 A;  1XBO A;  3QCH A;  5K25 A;  4HRF A;  3U96 A;  4QBW A;  4ZI4 A;  3MOZ A;  2BIJ A;  4OHI A;  2CNF A;  3EZZ A;  1NZ7 A;  4Z6B A;  2B07 A;  1ECV A;  2CM7 A;  2F6F A;  2B4P A;  2OOQ A;  1XRI A;  2QDP A;  3D44 A;  3I36 A;  2NLK A;  4I8N A;  5GTJ A;  1BZH A;  1ZZW A;  3F41 A;  1NWE A;  2BV5 A;  4R0S A;  3ZMP A;  1U24 A;  3S3H A;  2I6I A;  2I6O A;  4RH9 A;  1ONZ A;  5M43 A;  5K22 A;  4WOH A;  5K9W A;  2F70 A;  1WAX A;  2Y2F A;  5BZZ A;  2VEX A;  1G4U S;  3D1H A;  2AHS A;  1C87 A;  4GRY A;  4B04 A;  4JBC A;  2HCM A;  2I42 A;  3EAX A;  3QCG A;  2MBC A;  1U26 A;  3B7O A;  5KA2 A;  2J17 A;  3BRH A;  4GRZ A;  4NX8 A;  4AZ1 A;  4OHH A;  1T4J A;  1YGR A;  1J4X A;  1ZCL A;  2CNI A;  4PVG A;  4BPC A;  4D3R A;  1OEU A;  4H1O A;  2PBN A;  4RKK A;  5KA1 A;  4YR8 B;  1FPZ A;  1LAR A;  4RI4 A;  1FPR A;  3CM3 A;  2PA5 A;  1G7F A;  4NWF A;  3SME A;  1QXK A;  2Q47 A;  5I6V A;  1EEN A;  1YZ4 A;  5HDE A;  4HJQ A;  4RDD A;  5IBM A;  2CNG A;  1X24 A;  3LJ8 A;  1Q6S A;  2HC2 A;  2NTA A;  5KA3 A;  2I4E A;  4WU2 A;  2WGP A;  3QCM A;  4HJP A;  3N0A A;  1ONY A;  5KAB A;  1QZ0 A;  2I6J A;  2OUD A;  2PT0 A;  4JMK A;  5BX1 A;  4JMJ A;  2I1Y A;  2YDU A;  1G7G A;  3D1O A;  3I7Z A;  2OZ5 A;  1LYV A;  4ZRT A;  5EHR A;  3RO1 A;  3SR9 A;  1PTY A;  2E0T A;  5AWX A;  1OEO X;  3ZM0 A;  2CMA A;  2QDM A;  3QKQ A;  2A3K A;  3V0D A;  1V3A A;  2F6V A;  4QUM A;  2BGE A;  3NME A;  4IKC A;  2CM2 A;  5KA9 A;  1WCH A;  3RZ2 A;  4ERC A;  1C83 A;  2CNE A;  4DGP A;  3RGQ A;  4TVV A;  4MBB A;  4QBE A;  1LQF A;  5K9V A;  2QEP A;  3QCF A;  4R0T A;  4NWG A;  2J16 B;  1WRM A;  2R0B A;  1L8G A;  1I57 A;  4ICZ A;  1YTN A;  2AZR A;  4H34 A;  1OHD A;  5MMZ B;  2CFV A;  4KYR A;  4S0G A;  1YPT A;  3O4S A;  1T48 A;  1SUG A;  2I6M A;  4RHG A;  3V0E A;  3F9B A;  4J51 A;  3QKP A;  2VEY A;  2H4K A;  4BJO A;  1G4W R;  3ZMQ A;  5LXQ B;  1XXV A;  2ESB A;  1PTV A;  1A5Y A;  2QBP A;  4QUN A;  2I4G A;  2QCJ A;  4D3Q A;  1YWF A;  1BZC A;  3QCI A;  1G1G A;  1PYN A;  3BLT A;  1Q6T A;  3O4U A;  4GS0 A;  3AWF A;  1C86 A;  2CNH A;  2QBS A;  3A5K A;  4D3P A;  3AWE A;  1EEO A;  3O5X A;  2RF6 A;  4QAP A;  1OHC A;  1T49 A;  1XXP A;  2BZL A;  1NO6 A;  4GE2 A;  4YAA A;  3F9A A;  2VEW A;  3S3E A;  1C85 A;  2G59 A;  4GFV A;  1NL9 A;  4R30 A;  2VEV A;  2P4D A;  3ZM1 A;  1C88 A;  2ZMM A;  3S4E A;  2Y96 A;  2M3V A;  3S3K A;  1YGU A;  2H03 A;  3V0J A;  1U25 A;  2BGD A;  1NNY A;  4GE6 A;  2HVL A;  1OEV A;  3EU0 A;  1D5R A;  4OHL A;  1Q6M A;  5BUG A;  2GP0 A;  2F71 A;  2J16 A;  2QCT A;  4GWF A;  4OHE A;  3QCE A;  1YN9 A;  2F6Z A;  3ZM2 A;  4NND A;  3H2X A;  1P15 A;  1YTS A;  3EMU A;  2HNP A;  2CM8 A;  3D42 A;  4RH5 A;  1C84 A;  1G1F A;  1L8K A;  1NWL A;  1AAX A;  2HB1 A;  3M4U A;  1JLN A;  1KAV A;  1OEM X;  5KAD A;  2F6T A;  4WTY A;  2JJD A;  1OES A;  3BLU A;  2PI7 A;  2HNQ A;  4RI5 A;  2NZ6 A;  2OC3 A;  3D1Q A;  3V0F A;  2I4H A;  2CM3 A;  2IMG A;  3QCC A;  4OHD A;  2CMB A;  2GWO A;  2PQ5 A;  2NT2 A;  1Q6J A;  1XM2 A;  3ZV2 A;  1YFO A;  3O4T A;  3PS5 A;  2I3R A;  2H4G A;  3S4O A;  2I5X A;  2HXP A;  3QCN A;  2QBR A;  3BM8 A;  2B3O A;  1KAK A;  3AWG A;  4KYQ A;  3S3F A;  2B4U A;  2HY3 A;  1PA1 A;  1PTU A;  3A5J A;  2F6W A;  4JNB A;  1PH0 A;  3MOW A;  2H4V A;  2G6Z A;  1Q6N A;  5IBS A;  4QAH A;  2ZN7 A;  1FQ1 A;  4PYH A;  3QCB A;  2NV5 A;  2B49 A;  2I3U A;  4WU3 A;  2DXP A;  2FJM A;  3RGO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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