1ONZA

Oxalyl-aryl-amino benzoic acid inhibitors of ptp1b, compound 8b
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
282
structure length
282
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery and Structure-Activity Relationship of Oxalylarylaminobenzoic Acids as Inhibitors of Protein Tyrosine Phosphatase 1B
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein-tyrosine phosphatase, non-receptor type 1
total genus 96
structure length 282
sequence length 282
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2003-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1onzA00
3H2XA 1U26A 4Y2EA 3RGOA 2F70A 1OESA 3D1QA 2H4VA 1YFOA 2ESBA 3RZ2A 2QDCA 2BZLA 3D1HA 2H02A 1YGRA 2NTAA 1FPRA 3QKQA 2I3UA 4KI9A 3O4TA 5KA0A 1NL9A 1C86A 2OC3A 1QZ0A 1A5YA 1U24A 4RI4A 4D3QA 4MBBA 1SUGA 1YTWA 5KAAA 2QBRA 2CNFA 1G1GA 3O5XA 3RGQA 3QCLA 2Y96A 1PYNA 2NZ6A 3QCMA 2H03A 4QBWA 1V3AA 5EHRA 2DXPA 2P6XA 4RH9A 3I7ZA 1XRIA 1OEUA 2C46A 2NV5A 3QCGA 1NNYA 3AWGA 4ZRTA 4DGXA 3QCHA 2CM2A 2OZ5A 3CM3A 2B3OA 2ZMMA 1JF7A 2F71A 2PI7A 4JNBA 3S3KA 2B49A 3QCNA 2NT7A 2J16A 4I8NA 1PTYA 3BRHA 2CJZA 3QCJA 2PT0A 3SMEA 4GE5A 4BJOA 1Q6JA 4BPCA 3V0FA 1PTTA 2Q47A 3AWFA 5BZXA 1J4XA 3EMUA 2QBQA 2I6IA 4RHGA 5M43A 4B04A 2OOQA 3QCEA 1YWFA 2HNPA 4R30A 4YAAA 1C87A 1ECVA 1PA1A 3BLUA 4S0GA 4QUNA 4JMKA 1ZZWA 5KABA 3RO1A 1NZ7A 4ERCA 4RKKA 1OEVA 2CMCA 4KYQA 1Q6NA 3I80A 2AZRA 2QEPA 2VEXA 2I4GA 2F6ZA 1C85A 1LARA 4NWGA 3MOZA 2VEYA 1U25A 2QCTA 3V0DA 3EB1A 4QBEA 1T4JA 1KAKA 2CM7A 2G59A 1P15A 4NWFA 4NYHA 2B4SA 1G4WR 2HY3A 3S4EA 1C88A 1PA9A 2FJNA 5K9WA 3V0EA 3EU0A 2MBCA 3S3FA 2WGPA 3MMJA 5KA4A 1MKPA 2QBPA 5IBSA 5EHPA 4H1OA 1OETA 1Q6PA 1XXPA 2GJTA 3QCDA 1JLNA 3LJ8A 2QDPA 1LYVA 3QCBA 5KA8A 2PBNA 3F9BA 1PTUA 3OLRA 1OEMX 4QUMA 5KA9A 2QCJA 2HC1A 3NMEA 1YTSA 2I75A 3S4OA 1G1FA 1OHEA 3O3LA 2BIJA 5I6VA 1NO6A 4HRFA 4HJQA 4ICZA 4JMJA 2OUDA 1I9SA 1RXDA 1X24A 1GFYA 1PXHA 2I4EA 1PTVA 3A5JA 2FJMA 2I4HA 2PA5A 4WU3A 1L8KA 1XBOA 5KACA 5MMZB 3D9CA 5IBMA 4GWFA 1ZCLA 1G7GA 1BZJA 1Q6SA 1XXVA 3BM8A 1BZHA 1WAXA 2BGDA 4PVGA 2SHPA 1OHDA 5KA2A 3ZMPA 1G7FA 2B07A 4QAHA 2Q05A 3OMHA 3ZMQA 4GFUA 1C84A 3ZM0A 4QAPA 4R0TA 2FH7A 3BLTA 4GS0A 4KYRA 3I36A 4IKCA 3QCIA 1YN9A 1ZC0A 3SR9A 4ZN5A 1G1HA 4GFVA 2HCMA 3S3EA 2QBSA 2NT2A 2P4DA 3S3HA 2BGEA 1M3GA 2IMGA 3QCFA 3V0IA 2NLKA 1VHRA 2CMAA 3GXGA 2QDMA 4RH5A 2G6ZA 3QCKA 5K9VA 1FQ1A 3F9AA 3B7OA 2J16B 4TVVA 2B4OA 2CNGA 3MOWA 1I57A 3O4SA 4GE2A 1YZ4A 2BV5A 2F6YA 2I5XA 2F46A 3QCCA 2R0BA 3GXHA 1L8GA 4JBCA 1I9TA 4NX8A 2I6OA 5LXQB 2VEWA 3O4UA 4YR8B 4WU2A 1C83A 2I1YA 4Z6BA 2GP0A 3V0GA 2CNIA 2HVLA 4HJPA 2PQ5A 4GRZA 4OHDA 2CMBA 4NNDA 2PSZA 2HXPA 2HB1A 3EAXA 5AWXA 5GTJA 3A5KA 4D3RA 1PH0A 1Q1MA 4GRYA 5HDEA 4DGPA 1EENA 3D1OA 2VEUA 1EEOA 4OHLA 2CFVA 3D42A 1OEOX 2B4PA 2CM3A 3ZM3A 5KA3A 2C7SA 5KADA 3M4UA 2HNQA 1YGUA 5J8RA 4ZI4A 1AAXA 3V0JA 2F6TA 5BX1A 1Q6MA 2JJDA 1Q6TA 3QKPA 4OHIA 1WCHA 1D5RA 2RF6A 1NWEA 1ONYA 2CNEA 2M3VA 4J51A 1KAVA 2E0TA 4WOHA 3F41A 1RPMA 2GWOA 5BZZA 5K24A 2A3KA 4H34A 2VEVA 3D44A 2I42A 3ZM2A 5BUGA 4OHEA 2I6PA 4Y14A 4RDDA 1FPZA 3F99A 4D3PA 1T48A 5K22A 2I6MA 1OHCA 4PYHA 4OHHA 4RI5A 3EZZA 2F6WA 2F6FA 1XM2A 5KA7A 1YPTA 2YDUA 2I3RA 3AWEA 5KA1A 2Y2FA 5K25A 2H4KA 2B4UA 3ZM1A 2F6VA 1LQFA 1QXKA 1YTNA 1T49A 3V0HA 3U96A 1ZCKA 2ZN7A 1R6HA 2HC2A 1GWZA 3CWEA 5K23A 4AZ1A 2H04A 3PS5A 4WTYA 1WRMA 2AHSA 3ZV2A 4R0SA 2I6JA 1ONZA 2CNHA 1BZCA 3F81A 2H4GA 2CM8A 2A8BA 3N0AA 1G4US 1NWLA 2J17A 4GE6A
chains in the Genus database with same CATH superfamily
3H2XA 1U26A 4Y2EA 1O5ZA 3RGOA 2F70A 4C13A 1JBVA 1OESA 3D1QA 1GQYA 2H4VA 1YFOA 2ESBA 3RZ2A 2QDCA 2BZLA 3D1HA 2H02A 1YGRA 2NTAA 1FPRA 3QKQA 2I3UA 4BUCA 4KI9A 3O4TA 5KA0A 1NL9A 1C86A 2OC3A 1QZ0A 1A5YA 1U24A 4RI4A 4D3QA 4MBBA 1SUGA 1YTWA 5KAAA 2JFHA 2QBRA 1UAGA 2CNFA 1G1GA 3O5XA 3RGQA 3QCLA 2Y96A 1PYNA 2NZ6A 3QCMA 2H03A 4QBWA 1V3AA 5EHRA 2DXPA 2P6XA 4RH9A 2XJAA 3I7ZA 1XRIA 1OEUA 2C46A 2NV5A 3QCGA 1NNYA 3AWGA 4ZRTA 4DGXA 3QCZA 3QCHA 2CM2A 2OZ5A 3CM3A 2B3OA 2ZMMA 1JF7A 2F71A 2PI7A 4JNBA 3S3KA 2B49A 1JBWA 3QCNA 2NT7A 2J16A 4I8NA 1PTYA 1EEHA 3BRHA 1E8CA 2CJZA 2JFGA 3QCJA 2PT0A 3SMEA 4GE5A 4BJOA 2WJPA 1Q6JA 4BPCA 3V0FA 1PTTA 2Q47A 3AWFA 5BZXA 1J4XA 3EMUA 2QBQA 2I6IA 2Y68A 4RHGA 5M43A 4B04A 2OOQA 3QCEA 1YWFA 2HNPA 4R30A 4YAAA 1C87A 1GQQA 3NRSA 2GCAA 1ECVA 1PA1A 3BLUA 4S0GA 4QUNA 4JMKA 2F00A 1ZZWA 5KABA 3RO1A 2Y66A 1NZ7A 4ERCA 4RKKA 1OEVA 2CMCA 1P3DA 4KYQA 1Q6NA 3I80A 4QDIA 5A5FA 2AZRA 2QEPA 2VEXA 2VTDA 1P31A 2I4GA 2XPCA 2F6ZA 1C85A 2GCBA 4ZIYA 2UUPA 1LARA 4NWGA 2VTEA 3MOZA 2VEYA 1U25A 2QCTA 3V0DA 3EB1A 4QBEA 3MVNA 1T4JA 1KAKA 2CM7A 2G59A 1P15A 4NWFA 4NYHA 2B4SA 1G4WR 2HY3A 3S4EA 1C88A 1PA9A 2FJNA 5K9WA 3V0EA 3EU0A 2MBCA 3S3FA 2WGPA 3MMJA 5KA4A 1MKPA 2QBPA 5IBSA 2JFFA 4H1OA 5EHPA 1OETA 1Q6PA 1XXPA 2GJTA 3QCDA 1FGSA 1JLNA 3LJ8A 2QDPA 1LYVA 3QCBA 4UAGA 5KA8A 3PYZA 2PBNA 3F9BA 1PTUA 3OLRA 1OEMX 4QUMA 5KA9A 2QCJA 2HC1A 3NMEA 1YTSA 2I75A 3S4OA 1G1FA 1OHEA 3O3LA 2BIJA 5I6VA 1NO6A 4HRFA 4HJQA 2WTZA 4ICZA 4JMJA 2OUDA 1I9SA 1RXDA 1X24A 4HV4A 1GFYA 1PXHA 2I4EA 1PTVA 3A5JA 3ZM5A 2FJMA 2I4HA 2PA5A 4WU3A 1L8KA 1XBOA 5KACA 5MMZB 2AM2A 3D9CA 5IBMA 4GWFA 1ZCLA 1G7GA 1BZJA 1Q6SA 1XXVA 3BM8A 1BZHA 1WAXA 2Y67A 2BGDA 4PVGA 2SHPA 1OHDA 5KA2A 2X5OA 3ZMPA 1G7FA 2B07A 4QAHA 2VOSA 2Q05A 3OMHA 3ZMQA 4GFUA 1W78A 1C84A 3ZM0A 4QAPA 4R0TA 2FH7A 3BLTA 4GS0A 4CVKA 4KYRA 1GG4A 3I36A 4IKCA 3QCIA 1YN9A 1ZC0A 3SR9A 4ZN5A 1G1HA 4GFVA 2HCMA 3S3EA 2QBSA 2NT2A 2P4DA 2GC6A 3S3HA 2BGEA 1M3GA 2IMGA 3QCFA 3V0IA 2NLKA 1VHRA 2CMAA 3GXGA 2QDMA 4RH5A 4CVLA 2G6ZA 3QCKA 5K9VA 1FQ1A 3F9AA 3B7OA 2J16B 4TVVA 2B4OA 2CNGA 3MOWA 1I57A 3O4SA 4GE2A 1YZ4A 2BV5A 2F6YA 2I5XA 2F46A 3QCCA 2R0BA 3UAGA 3GXHA 1L8GA 4JBCA 1I9TA 4NX8A 2I6OA 5LXQB 2VEWA 2GC5A 2UUOA 3O4UA 4YR8B 1E0DA 4WU2A 1W7KA 1C83A 2I1YA 4Z6BA 2GP0A 3V0GA 2CNIA 2HVLA 4HJPA 2PQ5A 4GRZA 4OHDA 2CMBA 4NNDA 2PSZA 2HXPA 2HB1A 3EAXA 5AWXA 5GTJA 3A5KA 4D3RA 1PH0A 1Q1MA 4GRYA 5HDEA 4DGPA 1EENA 3D1OA 2VEUA 3HN7A 1EEOA 4OHLA 2CFVA 3D42A 1OEOX 2B4PA 2CM3A 3ZM3A 5KA3A 2UAGA 2VORA 2C7SA 5KADA 3M4UA 2HNQA 1YGUA 5J8RA 4ZI4A 1AAXA 3V0JA 2F6TA 5BX1A 1Q6MA 2JJDA 1Q6TA 3QKPA 4OHIA 1WCHA 1D5RA 2RF6A 1NWEA 2Y1OA 1ONYA 2CNEA 2M3VA 4J51A 1KAVA 2E0TA 4WOHA 3F41A 1RPMA 2GWOA 3ZL8A 5BZZA 5K24A 2A3KA 3LK7A 4H34A 2VEVA 3D44A 2I42A 5A5EA 3ZM2A 5BUGA 1J6UA 4OHEA 2I6PA 4Y14A 4RDDA 1FPZA 3F99A 4D3PA 1T48A 5K22A 2I6MA 1OHCA 4PYHA 4OHHA 4RI5A 3EZZA 2F6WA 2F6FA 1XM2A 5KA7A 1YPTA 2AM1A 2I3RA 2YDUA 3AWEA 5KA1A 3ZM6A 2Y2FA 5K25A 2H4KA 2B4UA 3ZM1A 2F6VA 1LQFA 1QXKA 1YTNA 1T49A 3V0HA 3U96A 1ZCKA 2ZN7A 1R6HA 2HC2A 1GWZA 3CWEA 5K23A 4BUBA 4AZ1A 2H04A 3N2AA 3PS5A 4WTYA 1WRMA 4QF5A 2AHSA 3ZV2A 4R0SA 2I6JA 4CVMA 1ONZA 2CNHA 1BZCA 3F81A 4C12A 2H4GA 2CM8A 2A8BA 3N0AA 1G4US 1NWLA 2J17A 4GE6A
chains in the Genus database with same CATH topology
3H2XA 1U26A 4Y2EA 3RGOA 2F70A 1OESA 3D1QA 2H4VA 1YFOA 2ESBA 3RZ2A 2QDCA 2BZLA 3D1HA 2H02A 1YGRA 2NTAA 1FPRA 3QKQA 2I3UA 4KI9A 3O4TA 5KA0A 1NL9A 1C86A 2OC3A 1QZ0A 1A5YA 1U24A 4RI4A 4D3QA 4MBBA 1SUGA 1YTWA 5KAAA 2QBRA 2CNFA 1G1GA 3O5XA 3RGQA 3QCLA 2Y96A 1PYNA 2NZ6A 3QCMA 2H03A 4QBWA 1V3AA 5EHRA 2DXPA 2P6XA 4RH9A 3I7ZA 1XRIA 1OEUA 2C46A 2NV5A 3QCGA 1NNYA 3AWGA 4ZRTA 4DGXA 3QCHA 2CM2A 2OZ5A 3CM3A 2B3OA 2ZMMA 1JF7A 2F71A 2PI7A 4JNBA 3S3KA 2B49A 3QCNA 2NT7A 2J16A 4I8NA 1PTYA 3BRHA 2CJZA 3QCJA 2PT0A 3SMEA 4GE5A 4BJOA 1Q6JA 4BPCA 3V0FA 1PTTA 2Q47A 3AWFA 5BZXA 1J4XA 3EMUA 2QBQA 2I6IA 4RHGA 5M43A 4B04A 2OOQA 3QCEA 1YWFA 2HNPA 4R30A 4YAAA 1C87A 1ECVA 1PA1A 3BLUA 4S0GA 4QUNA 4JMKA 1ZZWA 5KABA 3RO1A 1NZ7A 4ERCA 4RKKA 1OEVA 2CMCA 4KYQA 1Q6NA 3I80A 2AZRA 2QEPA 2VEXA 2I4GA 2F6ZA 1C85A 1LARA 4NWGA 3MOZA 2VEYA 1U25A 2QCTA 3V0DA 3EB1A 4QBEA 1T4JA 1KAKA 2CM7A 2G59A 1P15A 4NWFA 4NYHA 2B4SA 1G4WR 2HY3A 3S4EA 1C88A 1PA9A 2FJNA 5K9WA 3V0EA 3EU0A 2MBCA 3S3FA 2WGPA 3MMJA 5KA4A 1MKPA 2QBPA 5IBSA 5EHPA 4H1OA 1OETA 1Q6PA 1XXPA 2GJTA 3QCDA 1JLNA 3LJ8A 2QDPA 1LYVA 3QCBA 5KA8A 2PBNA 3F9BA 1PTUA 3OLRA 1OEMX 4QUMA 5KA9A 2QCJA 2HC1A 3NMEA 1YTSA 2I75A 3S4OA 1G1FA 1OHEA 3O3LA 2BIJA 5I6VA 1NO6A 4HRFA 4HJQA 4ICZA 4JMJA 2OUDA 1I9SA 1RXDA 1X24A 1GFYA 1PXHA 2I4EA 1PTVA 3A5JA 2FJMA 2I4HA 2PA5A 4WU3A 1L8KA 1XBOA 5KACA 5MMZB 3D9CA 5IBMA 4GWFA 1ZCLA 1G7GA 1BZJA 1Q6SA 1XXVA 3BM8A 1BZHA 1WAXA 2BGDA 4PVGA 2SHPA 1OHDA 5KA2A 3ZMPA 1G7FA 2B07A 4QAHA 2Q05A 3OMHA 3ZMQA 4GFUA 1C84A 3ZM0A 4QAPA 4R0TA 2FH7A 3BLTA 4GS0A 4KYRA 3I36A 4IKCA 3QCIA 1YN9A 1ZC0A 3SR9A 4ZN5A 1G1HA 4GFVA 2HCMA 3S3EA 2QBSA 2NT2A 2P4DA 3S3HA 2BGEA 1M3GA 2IMGA 3QCFA 3V0IA 2NLKA 1VHRA 2CMAA 3GXGA 2QDMA 4RH5A 2G6ZA 3QCKA 5K9VA 1FQ1A 3F9AA 3B7OA 2J16B 4TVVA 2B4OA 2CNGA 3MOWA 1I57A 3O4SA 4GE2A 1YZ4A 2BV5A 2F6YA 2I5XA 2F46A 3QCCA 2R0BA 3GXHA 1L8GA 4JBCA 1I9TA 4NX8A 2I6OA 5LXQB 2VEWA 3O4UA 4YR8B 4WU2A 1C83A 2I1YA 4Z6BA 2GP0A 3V0GA 2CNIA 2HVLA 4HJPA 2PQ5A 4GRZA 4OHDA 2CMBA 4NNDA 2PSZA 2HXPA 2HB1A 3EAXA 5AWXA 5GTJA 3A5KA 4D3RA 1PH0A 1Q1MA 4GRYA 5HDEA 4DGPA 1EENA 3D1OA 2VEUA 1EEOA 4OHLA 2CFVA 3D42A 1OEOX 2B4PA 2CM3A 3ZM3A 5KA3A 2C7SA 5KADA 3M4UA 2HNQA 1YGUA 5J8RA 4ZI4A 1AAXA 3V0JA 2F6TA 5BX1A 1Q6MA 2JJDA 1Q6TA 3QKPA 4OHIA 1WCHA 1D5RA 2RF6A 1NWEA 1ONYA 2CNEA 2M3VA 4J51A 1KAVA 2E0TA 4WOHA 3F41A 1RPMA 2GWOA 5BZZA 5K24A 2A3KA 4H34A 2VEVA 3D44A 2I42A 3ZM2A 5BUGA 4OHEA 2I6PA 4Y14A 4RDDA 1FPZA 3F99A 4D3PA 1T48A 5K22A 2I6MA 1OHCA 4PYHA 4OHHA 4RI5A 3EZZA 2F6WA 2F6FA 1XM2A 5KA7A 1YPTA 2YDUA 2I3RA 3AWEA 5KA1A 2Y2FA 5K25A 2H4KA 2B4UA 3ZM1A 2F6VA 1LQFA 1QXKA 1YTNA 1T49A 3V0HA 3U96A 1ZCKA 2ZN7A 1R6HA 2HC2A 1GWZA 3CWEA 5K23A 4AZ1A 2H04A 3PS5A 4WTYA 1WRMA 2AHSA 3ZV2A 4R0SA 2I6JA 1ONZA 2CNHA 1BZCA 3F81A 2H4GA 2CM8A 2A8BA 3N0AA 1G4US 1NWLA 2J17A 4GE6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H2X A;  1U26 A;  4Y2E A;  3RGO A;  2F70 A;  1OES A;  3D1Q A;  2H4V A;  1YFO A;  2ESB A;  3RZ2 A;  2QDC A;  2BZL A;  3D1H A;  2H02 A;  1YGR A;  2NTA A;  1FPR A;  3QKQ A;  2I3U A;  4KI9 A;  3O4T A;  5KA0 A;  1NL9 A;  1C86 A;  2OC3 A;  1QZ0 A;  1A5Y A;  1U24 A;  4RI4 A;  4D3Q A;  4MBB A;  1SUG A;  1YTW A;  5KAA A;  2QBR A;  2CNF A;  1G1G A;  3O5X A;  3RGQ A;  3QCL A;  2Y96 A;  1PYN A;  2NZ6 A;  3QCM A;  2H03 A;  4QBW A;  1V3A A;  5EHR A;  2DXP A;  2P6X A;  4RH9 A;  3I7Z A;  1XRI A;  1OEU A;  2C46 A;  2NV5 A;  3QCG A;  1NNY A;  3AWG A;  4ZRT A;  4DGX A;  3QCH A;  2CM2 A;  2OZ5 A;  3CM3 A;  2B3O A;  2ZMM A;  1JF7 A;  2F71 A;  2PI7 A;  4JNB A;  3S3K A;  2B49 A;  3QCN A;  2NT7 A;  2J16 A;  4I8N A;  1PTY A;  3BRH A;  2CJZ A;  3QCJ A;  2PT0 A;  3SME A;  4GE5 A;  4BJO A;  1Q6J A;  4BPC A;  3V0F A;  1PTT A;  2Q47 A;  3AWF A;  5BZX A;  1J4X A;  3EMU A;  2QBQ A;  2I6I A;  4RHG A;  5M43 A;  4B04 A;  2OOQ A;  3QCE A;  1YWF A;  2HNP A;  4R30 A;  4YAA A;  1C87 A;  1ECV A;  1PA1 A;  3BLU A;  4S0G A;  4QUN A;  4JMK A;  1ZZW A;  5KAB A;  3RO1 A;  1NZ7 A;  4ERC A;  4RKK A;  1OEV A;  2CMC A;  4KYQ A;  1Q6N A;  3I80 A;  2AZR A;  2QEP A;  2VEX A;  2I4G A;  2F6Z A;  1C85 A;  1LAR A;  4NWG A;  3MOZ A;  2VEY A;  1U25 A;  2QCT A;  3V0D A;  3EB1 A;  4QBE A;  1T4J A;  1KAK A;  2CM7 A;  2G59 A;  1P15 A;  4NWF A;  4NYH A;  2B4S A;  1G4W R;  2HY3 A;  3S4E A;  1C88 A;  1PA9 A;  2FJN A;  5K9W A;  3V0E A;  3EU0 A;  2MBC A;  3S3F A;  2WGP A;  3MMJ A;  5KA4 A;  1MKP A;  2QBP A;  5IBS A;  5EHP A;  4H1O A;  1OET A;  1Q6P A;  1XXP A;  2GJT A;  3QCD A;  1JLN A;  3LJ8 A;  2QDP A;  1LYV A;  3QCB A;  5KA8 A;  2PBN A;  3F9B A;  1PTU A;  3OLR A;  1OEM X;  4QUM A;  5KA9 A;  2QCJ A;  2HC1 A;  3NME A;  1YTS A;  2I75 A;  3S4O A;  1G1F A;  1OHE A;  3O3L A;  2BIJ A;  5I6V A;  1NO6 A;  4HRF A;  4HJQ A;  4ICZ A;  4JMJ A;  2OUD A;  1I9S A;  1RXD A;  1X24 A;  1GFY A;  1PXH A;  2I4E A;  1PTV A;  3A5J A;  2FJM A;  2I4H A;  2PA5 A;  4WU3 A;  1L8K A;  1XBO A;  5KAC A;  5MMZ B;  3D9C A;  5IBM A;  4GWF A;  1ZCL A;  1G7G A;  1BZJ A;  1Q6S A;  1XXV A;  3BM8 A;  1BZH A;  1WAX A;  2BGD A;  4PVG A;  2SHP A;  1OHD A;  5KA2 A;  3ZMP A;  1G7F A;  2B07 A;  4QAH A;  2Q05 A;  3OMH A;  3ZMQ A;  4GFU A;  1C84 A;  3ZM0 A;  4QAP A;  4R0T A;  2FH7 A;  3BLT A;  4GS0 A;  4KYR A;  3I36 A;  4IKC A;  3QCI A;  1YN9 A;  1ZC0 A;  3SR9 A;  4ZN5 A;  1G1H A;  4GFV A;  2HCM A;  3S3E A;  2QBS A;  2NT2 A;  2P4D A;  3S3H A;  2BGE A;  1M3G A;  2IMG A;  3QCF A;  3V0I A;  2NLK A;  1VHR A;  2CMA A;  3GXG A;  2QDM A;  4RH5 A;  2G6Z A;  3QCK A;  5K9V A;  1FQ1 A;  3F9A A;  3B7O A;  2J16 B;  4TVV A;  2B4O A;  2CNG A;  3MOW A;  1I57 A;  3O4S A;  4GE2 A;  1YZ4 A;  2BV5 A;  2F6Y A;  2I5X A;  2F46 A;  3QCC A;  2R0B A;  3GXH A;  1L8G A;  4JBC A;  1I9T A;  4NX8 A;  2I6O A;  5LXQ B;  2VEW A;  3O4U A;  4YR8 B;  4WU2 A;  1C83 A;  2I1Y A;  4Z6B A;  2GP0 A;  3V0G A;  2CNI A;  2HVL A;  4HJP A;  2PQ5 A;  4GRZ A;  4OHD A;  2CMB A;  4NND A;  2PSZ A;  2HXP A;  2HB1 A;  3EAX A;  5AWX A;  5GTJ A;  3A5K A;  4D3R A;  1PH0 A;  1Q1M A;  4GRY A;  5HDE A;  4DGP A;  1EEN A;  3D1O A;  2VEU A;  1EEO A;  4OHL A;  2CFV A;  3D42 A;  1OEO X;  2B4P A;  2CM3 A;  3ZM3 A;  5KA3 A;  2C7S A;  5KAD A;  3M4U A;  2HNQ A;  1YGU A;  5J8R A;  4ZI4 A;  1AAX A;  3V0J A;  2F6T A;  5BX1 A;  1Q6M A;  2JJD A;  1Q6T A;  3QKP A;  4OHI A;  1WCH A;  1D5R A;  2RF6 A;  1NWE A;  1ONY A;  2CNE A;  2M3V A;  4J51 A;  1KAV A;  2E0T A;  4WOH A;  3F41 A;  1RPM A;  2GWO A;  5BZZ A;  5K24 A;  2A3K A;  4H34 A;  2VEV A;  3D44 A;  2I42 A;  3ZM2 A;  5BUG A;  4OHE A;  2I6P A;  4Y14 A;  4RDD A;  1FPZ A;  3F99 A;  4D3P A;  1T48 A;  5K22 A;  2I6M A;  1OHC A;  4PYH A;  4OHH A;  4RI5 A;  3EZZ A;  2F6W A;  2F6F A;  1XM2 A;  5KA7 A;  1YPT A;  2YDU A;  2I3R A;  3AWE A;  5KA1 A;  2Y2F A;  5K25 A;  2H4K A;  2B4U A;  3ZM1 A;  2F6V A;  1LQF A;  1QXK A;  1YTN A;  1T49 A;  3V0H A;  3U96 A;  1ZCK A;  2ZN7 A;  1R6H A;  2HC2 A;  1GWZ A;  3CWE A;  5K23 A;  4AZ1 A;  2H04 A;  3PS5 A;  4WTY A;  1WRM A;  2AHS A;  3ZV2 A;  4R0S A;  2I6J A;  1ONZ A;  2CNH A;  1BZC A;  3F81 A;  2H4G A;  2CM8 A;  2A8B A;  3N0A A;  1G4U S;  1NWL A;  2J17 A;  4GE6 A; 
#chains in the Genus database with same CATH topology
 3H2X A;  1U26 A;  4Y2E A;  1O5Z A;  3RGO A;  2F70 A;  4C13 A;  1JBV A;  1OES A;  3D1Q A;  1GQY A;  2H4V A;  1YFO A;  2ESB A;  3RZ2 A;  2QDC A;  2BZL A;  3D1H A;  2H02 A;  1YGR A;  2NTA A;  1FPR A;  3QKQ A;  2I3U A;  4BUC A;  4KI9 A;  3O4T A;  5KA0 A;  1NL9 A;  1C86 A;  2OC3 A;  1QZ0 A;  1A5Y A;  1U24 A;  4RI4 A;  4D3Q A;  4MBB A;  1SUG A;  1YTW A;  5KAA A;  2JFH A;  2QBR A;  1UAG A;  2CNF A;  1G1G A;  3O5X A;  3RGQ A;  3QCL A;  2Y96 A;  1PYN A;  2NZ6 A;  3QCM A;  2H03 A;  4QBW A;  1V3A A;  5EHR A;  2DXP A;  2P6X A;  4RH9 A;  2XJA A;  3I7Z A;  1XRI A;  1OEU A;  2C46 A;  2NV5 A;  3QCG A;  1NNY A;  3AWG A;  4ZRT A;  4DGX A;  3QCZ A;  3QCH A;  2CM2 A;  2OZ5 A;  3CM3 A;  2B3O A;  2ZMM A;  1JF7 A;  2F71 A;  2PI7 A;  4JNB A;  3S3K A;  2B49 A;  1JBW A;  3QCN A;  2NT7 A;  2J16 A;  4I8N A;  1PTY A;  1EEH A;  3BRH A;  1E8C A;  2CJZ A;  2JFG A;  3QCJ A;  2PT0 A;  3SME A;  4GE5 A;  4BJO A;  2WJP A;  1Q6J A;  4BPC A;  3V0F A;  1PTT A;  2Q47 A;  3AWF A;  5BZX A;  1J4X A;  3EMU A;  2QBQ A;  2I6I A;  2Y68 A;  4RHG A;  5M43 A;  4B04 A;  2OOQ A;  3QCE A;  1YWF A;  2HNP A;  4R30 A;  4YAA A;  1C87 A;  1GQQ A;  3NRS A;  2GCA A;  1ECV A;  1PA1 A;  3BLU A;  4S0G A;  4QUN A;  4JMK A;  2F00 A;  1ZZW A;  5KAB A;  3RO1 A;  2Y66 A;  1NZ7 A;  4ERC A;  4RKK A;  1OEV A;  2CMC A;  1P3D A;  4KYQ A;  1Q6N A;  3I80 A;  4QDI A;  5A5F A;  2AZR A;  2QEP A;  2VEX A;  2VTD A;  1P31 A;  2I4G A;  2XPC A;  2F6Z A;  1C85 A;  2GCB A;  4ZIY A;  2UUP A;  1LAR A;  4NWG A;  2VTE A;  3MOZ A;  2VEY A;  1U25 A;  2QCT A;  3V0D A;  3EB1 A;  4QBE A;  3MVN A;  1T4J A;  1KAK A;  2CM7 A;  2G59 A;  1P15 A;  4NWF A;  4NYH A;  2B4S A;  1G4W R;  2HY3 A;  3S4E A;  1C88 A;  1PA9 A;  2FJN A;  5K9W A;  3V0E A;  3EU0 A;  2MBC A;  3S3F A;  2WGP A;  3MMJ A;  5KA4 A;  1MKP A;  2QBP A;  5IBS A;  2JFF A;  4H1O A;  5EHP A;  1OET A;  1Q6P A;  1XXP A;  2GJT A;  3QCD A;  1FGS A;  1JLN A;  3LJ8 A;  2QDP A;  1LYV A;  3QCB A;  4UAG A;  5KA8 A;  3PYZ A;  2PBN A;  3F9B A;  1PTU A;  3OLR A;  1OEM X;  4QUM A;  5KA9 A;  2QCJ A;  2HC1 A;  3NME A;  1YTS A;  2I75 A;  3S4O A;  1G1F A;  1OHE A;  3O3L A;  2BIJ A;  5I6V A;  1NO6 A;  4HRF A;  4HJQ A;  2WTZ A;  4ICZ A;  4JMJ A;  2OUD A;  1I9S A;  1RXD A;  1X24 A;  4HV4 A;  1GFY A;  1PXH A;  2I4E A;  1PTV A;  3A5J A;  3ZM5 A;  2FJM A;  2I4H A;  2PA5 A;  4WU3 A;  1L8K A;  1XBO A;  5KAC A;  5MMZ B;  2AM2 A;  3D9C A;  5IBM A;  4GWF A;  1ZCL A;  1G7G A;  1BZJ A;  1Q6S A;  1XXV A;  3BM8 A;  1BZH A;  1WAX A;  2Y67 A;  2BGD A;  4PVG A;  2SHP A;  1OHD A;  5KA2 A;  2X5O A;  3ZMP A;  1G7F A;  2B07 A;  4QAH A;  2VOS A;  2Q05 A;  3OMH A;  3ZMQ A;  4GFU A;  1W78 A;  1C84 A;  3ZM0 A;  4QAP A;  4R0T A;  2FH7 A;  3BLT A;  4GS0 A;  4CVK A;  4KYR A;  1GG4 A;  3I36 A;  4IKC A;  3QCI A;  1YN9 A;  1ZC0 A;  3SR9 A;  4ZN5 A;  1G1H A;  4GFV A;  2HCM A;  3S3E A;  2QBS A;  2NT2 A;  2P4D A;  2GC6 A;  3S3H A;  2BGE A;  1M3G A;  2IMG A;  3QCF A;  3V0I A;  2NLK A;  1VHR A;  2CMA A;  3GXG A;  2QDM A;  4RH5 A;  4CVL A;  2G6Z A;  3QCK A;  5K9V A;  1FQ1 A;  3F9A A;  3B7O A;  2J16 B;  4TVV A;  2B4O A;  2CNG A;  3MOW A;  1I57 A;  3O4S A;  4GE2 A;  1YZ4 A;  2BV5 A;  2F6Y A;  2I5X A;  2F46 A;  3QCC A;  2R0B A;  3UAG A;  3GXH A;  1L8G A;  4JBC A;  1I9T A;  4NX8 A;  2I6O A;  5LXQ B;  2VEW A;  2GC5 A;  2UUO A;  3O4U A;  4YR8 B;  1E0D A;  4WU2 A;  1W7K A;  1C83 A;  2I1Y A;  4Z6B A;  2GP0 A;  3V0G A;  2CNI A;  2HVL A;  4HJP A;  2PQ5 A;  4GRZ A;  4OHD A;  2CMB A;  4NND A;  2PSZ A;  2HXP A;  2HB1 A;  3EAX A;  5AWX A;  5GTJ A;  3A5K A;  4D3R A;  1PH0 A;  1Q1M A;  4GRY A;  5HDE A;  4DGP A;  1EEN A;  3D1O A;  2VEU A;  3HN7 A;  1EEO A;  4OHL A;  2CFV A;  3D42 A;  1OEO X;  2B4P A;  2CM3 A;  3ZM3 A;  5KA3 A;  2UAG A;  2VOR A;  2C7S A;  5KAD A;  3M4U A;  2HNQ A;  1YGU A;  5J8R A;  4ZI4 A;  1AAX A;  3V0J A;  2F6T A;  5BX1 A;  1Q6M A;  2JJD A;  1Q6T A;  3QKP A;  4OHI A;  1WCH A;  1D5R A;  2RF6 A;  1NWE A;  2Y1O A;  1ONY A;  2CNE A;  2M3V A;  4J51 A;  1KAV A;  2E0T A;  4WOH A;  3F41 A;  1RPM A;  2GWO A;  3ZL8 A;  5BZZ A;  5K24 A;  2A3K A;  3LK7 A;  4H34 A;  2VEV A;  3D44 A;  2I42 A;  5A5E A;  3ZM2 A;  5BUG A;  1J6U A;  4OHE A;  2I6P A;  4Y14 A;  4RDD A;  1FPZ A;  3F99 A;  4D3P A;  1T48 A;  5K22 A;  2I6M A;  1OHC A;  4PYH A;  4OHH A;  4RI5 A;  3EZZ A;  2F6W A;  2F6F A;  1XM2 A;  5KA7 A;  1YPT A;  2AM1 A;  2I3R A;  2YDU A;  3AWE A;  5KA1 A;  3ZM6 A;  2Y2F A;  5K25 A;  2H4K A;  2B4U A;  3ZM1 A;  2F6V A;  1LQF A;  1QXK A;  1YTN A;  1T49 A;  3V0H A;  3U96 A;  1ZCK A;  2ZN7 A;  1R6H A;  2HC2 A;  1GWZ A;  3CWE A;  5K23 A;  4BUB A;  4AZ1 A;  2H04 A;  3N2A A;  3PS5 A;  4WTY A;  1WRM A;  4QF5 A;  2AHS A;  3ZV2 A;  4R0S A;  2I6J A;  4CVM A;  1ONZ A;  2CNH A;  1BZC A;  3F81 A;  4C12 A;  2H4G A;  2CM8 A;  2A8B A;  3N0A A;  1G4U S;  1NWL A;  2J17 A;  4GE6 A; 
#chains in the Genus database with same CATH homology
 3H2X A;  1U26 A;  4Y2E A;  3RGO A;  2F70 A;  1OES A;  3D1Q A;  2H4V A;  1YFO A;  2ESB A;  3RZ2 A;  2QDC A;  2BZL A;  3D1H A;  2H02 A;  1YGR A;  2NTA A;  1FPR A;  3QKQ A;  2I3U A;  4KI9 A;  3O4T A;  5KA0 A;  1NL9 A;  1C86 A;  2OC3 A;  1QZ0 A;  1A5Y A;  1U24 A;  4RI4 A;  4D3Q A;  4MBB A;  1SUG A;  1YTW A;  5KAA A;  2QBR A;  2CNF A;  1G1G A;  3O5X A;  3RGQ A;  3QCL A;  2Y96 A;  1PYN A;  2NZ6 A;  3QCM A;  2H03 A;  4QBW A;  1V3A A;  5EHR A;  2DXP A;  2P6X A;  4RH9 A;  3I7Z A;  1XRI A;  1OEU A;  2C46 A;  2NV5 A;  3QCG A;  1NNY A;  3AWG A;  4ZRT A;  4DGX A;  3QCH A;  2CM2 A;  2OZ5 A;  3CM3 A;  2B3O A;  2ZMM A;  1JF7 A;  2F71 A;  2PI7 A;  4JNB A;  3S3K A;  2B49 A;  3QCN A;  2NT7 A;  2J16 A;  4I8N A;  1PTY A;  3BRH A;  2CJZ A;  3QCJ A;  2PT0 A;  3SME A;  4GE5 A;  4BJO A;  1Q6J A;  4BPC A;  3V0F A;  1PTT A;  2Q47 A;  3AWF A;  5BZX A;  1J4X A;  3EMU A;  2QBQ A;  2I6I A;  4RHG A;  5M43 A;  4B04 A;  2OOQ A;  3QCE A;  1YWF A;  2HNP A;  4R30 A;  4YAA A;  1C87 A;  1ECV A;  1PA1 A;  3BLU A;  4S0G A;  4QUN A;  4JMK A;  1ZZW A;  5KAB A;  3RO1 A;  1NZ7 A;  4ERC A;  4RKK A;  1OEV A;  2CMC A;  4KYQ A;  1Q6N A;  3I80 A;  2AZR A;  2QEP A;  2VEX A;  2I4G A;  2F6Z A;  1C85 A;  1LAR A;  4NWG A;  3MOZ A;  2VEY A;  1U25 A;  2QCT A;  3V0D A;  3EB1 A;  4QBE A;  1T4J A;  1KAK A;  2CM7 A;  2G59 A;  1P15 A;  4NWF A;  4NYH A;  2B4S A;  1G4W R;  2HY3 A;  3S4E A;  1C88 A;  1PA9 A;  2FJN A;  5K9W A;  3V0E A;  3EU0 A;  2MBC A;  3S3F A;  2WGP A;  3MMJ A;  5KA4 A;  1MKP A;  2QBP A;  5IBS A;  5EHP A;  4H1O A;  1OET A;  1Q6P A;  1XXP A;  2GJT A;  3QCD A;  1JLN A;  3LJ8 A;  2QDP A;  1LYV A;  3QCB A;  5KA8 A;  2PBN A;  3F9B A;  1PTU A;  3OLR A;  1OEM X;  4QUM A;  5KA9 A;  2QCJ A;  2HC1 A;  3NME A;  1YTS A;  2I75 A;  3S4O A;  1G1F A;  1OHE A;  3O3L A;  2BIJ A;  5I6V A;  1NO6 A;  4HRF A;  4HJQ A;  4ICZ A;  4JMJ A;  2OUD A;  1I9S A;  1RXD A;  1X24 A;  1GFY A;  1PXH A;  2I4E A;  1PTV A;  3A5J A;  2FJM A;  2I4H A;  2PA5 A;  4WU3 A;  1L8K A;  1XBO A;  5KAC A;  5MMZ B;  3D9C A;  5IBM A;  4GWF A;  1ZCL A;  1G7G A;  1BZJ A;  1Q6S A;  1XXV A;  3BM8 A;  1BZH A;  1WAX A;  2BGD A;  4PVG A;  2SHP A;  1OHD A;  5KA2 A;  3ZMP A;  1G7F A;  2B07 A;  4QAH A;  2Q05 A;  3OMH A;  3ZMQ A;  4GFU A;  1C84 A;  3ZM0 A;  4QAP A;  4R0T A;  2FH7 A;  3BLT A;  4GS0 A;  4KYR A;  3I36 A;  4IKC A;  3QCI A;  1YN9 A;  1ZC0 A;  3SR9 A;  4ZN5 A;  1G1H A;  4GFV A;  2HCM A;  3S3E A;  2QBS A;  2NT2 A;  2P4D A;  3S3H A;  2BGE A;  1M3G A;  2IMG A;  3QCF A;  3V0I A;  2NLK A;  1VHR A;  2CMA A;  3GXG A;  2QDM A;  4RH5 A;  2G6Z A;  3QCK A;  5K9V A;  1FQ1 A;  3F9A A;  3B7O A;  2J16 B;  4TVV A;  2B4O A;  2CNG A;  3MOW A;  1I57 A;  3O4S A;  4GE2 A;  1YZ4 A;  2BV5 A;  2F6Y A;  2I5X A;  2F46 A;  3QCC A;  2R0B A;  3GXH A;  1L8G A;  4JBC A;  1I9T A;  4NX8 A;  2I6O A;  5LXQ B;  2VEW A;  3O4U A;  4YR8 B;  4WU2 A;  1C83 A;  2I1Y A;  4Z6B A;  2GP0 A;  3V0G A;  2CNI A;  2HVL A;  4HJP A;  2PQ5 A;  4GRZ A;  4OHD A;  2CMB A;  4NND A;  2PSZ A;  2HXP A;  2HB1 A;  3EAX A;  5AWX A;  5GTJ A;  3A5K A;  4D3R A;  1PH0 A;  1Q1M A;  4GRY A;  5HDE A;  4DGP A;  1EEN A;  3D1O A;  2VEU A;  1EEO A;  4OHL A;  2CFV A;  3D42 A;  1OEO X;  2B4P A;  2CM3 A;  3ZM3 A;  5KA3 A;  2C7S A;  5KAD A;  3M4U A;  2HNQ A;  1YGU A;  5J8R A;  4ZI4 A;  1AAX A;  3V0J A;  2F6T A;  5BX1 A;  1Q6M A;  2JJD A;  1Q6T A;  3QKP A;  4OHI A;  1WCH A;  1D5R A;  2RF6 A;  1NWE A;  1ONY A;  2CNE A;  2M3V A;  4J51 A;  1KAV A;  2E0T A;  4WOH A;  3F41 A;  1RPM A;  2GWO A;  5BZZ A;  5K24 A;  2A3K A;  4H34 A;  2VEV A;  3D44 A;  2I42 A;  3ZM2 A;  5BUG A;  4OHE A;  2I6P A;  4Y14 A;  4RDD A;  1FPZ A;  3F99 A;  4D3P A;  1T48 A;  5K22 A;  2I6M A;  1OHC A;  4PYH A;  4OHH A;  4RI5 A;  3EZZ A;  2F6W A;  2F6F A;  1XM2 A;  5KA7 A;  1YPT A;  2YDU A;  2I3R A;  3AWE A;  5KA1 A;  2Y2F A;  5K25 A;  2H4K A;  2B4U A;  3ZM1 A;  2F6V A;  1LQF A;  1QXK A;  1YTN A;  1T49 A;  3V0H A;  3U96 A;  1ZCK A;  2ZN7 A;  1R6H A;  2HC2 A;  1GWZ A;  3CWE A;  5K23 A;  4AZ1 A;  2H04 A;  3PS5 A;  4WTY A;  1WRM A;  2AHS A;  3ZV2 A;  4R0S A;  2I6J A;  1ONZ A;  2CNH A;  1BZC A;  3F81 A;  2H4G A;  2CM8 A;  2A8B A;  3N0A A;  1G4U S;  1NWL A;  2J17 A;  4GE6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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