1Q6TA

The structure of phosphotyrosine phosphatase 1b in complex with compound 11
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
289
structure length
289
Chain Sequence
KLEFMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structural Basis for the Selectivity of Benzotriazole Inhibitors of Ptp1B
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein-tyrosine phosphatase, non-receptor type 1
total genus 96
structure length 289
sequence length 289
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2003-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1q6tA00
4WU2A 2I6PA 3EZZA 4QAHA 3QCCA 4ERCA 5KA8A 4WTYA 3F9BA 1Q6MA 2HB1A 1GWZA 3QCIA 5IBMA 3CM3A 3O5XA 5K9WA 1YN9A 1OEVA 1YGUA 4GWFA 4KI9A 1YWFA 4GE5A 5K24A 2P6XA 3S4OA 1ZCKA 3RZ2A 4D3QA 3B7OA 3S3HA 1R6HA 3O4SA 4GFUA 3QCFA 2HC1A 1X24A 1LYVA 4QBWA 4JNBA 2VEUA 2ESBA 2H03A 1KAKA 1OEOX 1PTVA 5K25A 3QKPA 2ZMMA 2FJNA 2I6OA 2P4DA 2CMAA 4GS0A 5J8RA 3QCLA 1EEOA 4YAAA 5KAAA 2I4EA 3QKQA 4HRFA 4OHHA 3MOZA 1XRIA 2ZN7A 3BRHA 2PQ5A 2OUDA 2F71A 1I9TA 3S4EA 1Q6JA 2G59A 3OLRA 2NZ6A 4I8NA 2I4GA 2B4PA 1VHRA 3U96A 4RHGA 5EHPA 1D5RA 2VEYA 2H4KA 3S3EA 1L8GA 5KA1A 3MOWA 1ZCLA 2HNQA 3F41A 2NT2A 2I3RA 1WRMA 1I9SA 2AZRA 2FH7A 3RGOA 1ONZA 1PTTA 3O4UA 3D1OA 2F6WA 2GP0A 2MBCA 2I6MA 1YGRA 1Q6NA 2QBRA 5LXQB 2CNGA 1NZ7A 3V0DA 2CM2A 3NMEA 2F46A 3D1HA 2HXPA 1FPZA 1G7FA 2E0TA 2BGDA 4HJPA 1C87A 1PXHA 1RXDA 3EU0A 3H2XA 2H04A 2QDMA 4BPCA 2PBNA 3QCJA 4JMJA 2BGEA 1JF7A 1ONYA 2OZ5A 2PI7A 2F6TA 2QDPA 1YPTA 2H4GA 2I6IA 4R0TA 4OHDA 1MKPA 1NNYA 1NWLA 3F81A 1U26A 1C84A 1BZCA 4WU3A 5GTJA 2R0BA 4HJQA 3QCHA 2CJZA 4NYHA 1ZC0A 3SR9A 2BV5A 3EB1A 2CNEA 3D1QA 1NL9A 2I4HA 2C46A 2PSZA 3F99A 2CNHA 5KABA 3O3LA 2HNPA 2CM3A 2Y96A 4QBEA 2YDUA 4OHLA 5BUGA 2B4UA 2RF6A 2HY3A 3S3KA 4H34A 2VEWA 2B07A 1YZ4A 4BJOA 2F6VA 3ZM1A 4JBCA 1XXPA 3QCBA 1C85A 2IMGA 3V0GA 5IBSA 2J17A 3V0EA 3M4UA 2I42A 4RH5A 4D3PA 3ZM2A 4DGXA 3I80A 3GXGA 2WGPA 4ZI4A 1M3GA 3CWEA 4MBBA 1I57A 1T48A 3PS5A 2NLKA 5KA0A 5KADA 1G1HA 2PT0A 1G4US 2CM7A 1Q6SA 1ZZWA 1G1FA 4RI5A 4R0SA 5KA4A 3D42A 1JLNA 4Y2EA 3BLUA 2CM8A 4DGPA 1YTSA 1QZ0A 3V0FA 2HCMA 1BZHA 2I1YA 4RDDA 1XM2A 5BX1A 3AWEA 5KACA 2I3UA 1P15A 1AAXA 2HC2A 1XXVA 4OHEA 4QUNA 3QCNA 1NWEA 2J16B 5KA3A 4PYHA 3ZMQA 4IKCA 3V0IA 2A3KA 2QBSA 1WCHA 1J4XA 4Y14A 3D9CA 2PA5A 1OHEA 3I36A 2M3VA 4ICZA 2Q47A 2HVLA 5KA7A 2OC3A 4GE2A 4KYQA 3ZM0A 1FPRA 3V0JA 4KYRA 1PH0A 3BLTA 5EHRA 1YFOA 1A5YA 1G1GA 1OESA 4R30A 3RO1A 3SMEA 3EMUA 3D44A 3GXHA 5K23A 4RH9A 1PTUA 3AWGA 2CNFA 5AWXA 1GFYA 1PA9A 3OMHA 3QCDA 4QUMA 3ZMPA 1OEMX 1PA1A 2CMBA 3A5JA 1LQFA 5HDEA 1L8KA 4AZ1A 3AWFA 1OEUA 2A8BA 4J51A 3V0HA 4GRYA 1C86A 2VEVA 2J16A 1LARA 1FQ1A 1OHCA 1PYNA 1ECVA 2NT7A 3ZV2A 2I5XA 1WAXA 1Q1MA 4D3RA 3O4TA 1XBOA 4ZRTA 4GRZA 3N0AA 2F6YA 1OHDA 1RPMA 2BIJA 1YTWA 2DXPA 4PVGA 3QCEA 4WOHA 4RKKA 4B04A 2C7SA 2BZLA 1KAVA 2AHSA 1Q6TA 2VEXA 4H1OA 1G4WR 3BM8A 2OOQA 3S3FA 4JMKA 4NX8A 5KA2A 5I6VA 2Q05A 5K9VA 1U25A 2B49A 1U24A 1BZJA 2CFVA 1C83A 2GJTA 5BZZA 4YR8B 2NTAA 4OHIA 5K22A 4QAPA 3F9AA 2QDCA 4ZN5A 3MMJA 4NWFA 3I7ZA 3EAXA 2F6FA 2B4OA 5KA9A 2Y2FA 1PTYA 3A5KA 5BZXA 3QCMA 1SUGA 4S0GA 3QCKA 2QCTA 4GE6A 2QCJA 2H02A 4GFVA 1V3AA 1EENA 4Z6BA 2QBPA 2CMCA 2B4SA 5M43A 5MMZB 3ZM3A 3RGQA 2QEPA 4RI4A 3LJ8A 2GWOA 1C88A 2B3OA 2JJDA 1YTNA 1T4JA 2F70A 2G6ZA 2SHPA 4NWGA 2I75A 2QBQA 1OETA 2CNIA 1G7GA 2FJMA 2NV5A 4NNDA 3QCGA 4TVVA 2I6JA 2H4VA 1T49A 1Q6PA 1QXKA 1NO6A 2F6ZA
chains in the Genus database with same CATH superfamily
4WU2A 2I6PA 3EZZA 4QAHA 3QCCA 2XPCA 4ERCA 5KA8A 4WTYA 3F9BA 1Q6MA 2HB1A 1GWZA 3QCIA 1JBWA 5IBMA 3CM3A 3O5XA 5K9WA 1YN9A 1OEVA 3HN7A 1YGUA 2VORA 2Y66A 4GWFA 4KI9A 1YWFA 4GE5A 5K24A 2P6XA 3ZM6A 3S4OA 1ZCKA 3RZ2A 4D3QA 3B7OA 3S3HA 1R6HA 3O4SA 4GFUA 1GQYA 3QCFA 2HC1A 2VOSA 1X24A 1LYVA 4QBWA 4JNBA 2VEUA 2ESBA 2H03A 1KAKA 1OEOX 1PTVA 2GC5A 5K25A 3QKPA 2ZMMA 2FJNA 4QF5A 2I6OA 2P4DA 2CMAA 4GS0A 5J8RA 3QCLA 1EEOA 4YAAA 5KAAA 2I4EA 3QKQA 4HRFA 3MVNA 4OHHA 3MOZA 1XRIA 2ZN7A 2WTZA 3BRHA 2PQ5A 2OUDA 2F71A 1I9TA 3S4EA 1Q6JA 2G59A 3OLRA 1W7KA 2NZ6A 4I8NA 2I4GA 2B4PA 1VHRA 3U96A 4RHGA 5EHPA 1D5RA 2VEYA 2VTDA 2JFGA 2H4KA 3S3EA 1L8GA 5KA1A 3MOWA 1ZCLA 2HNQA 3F41A 2NT2A 2I3RA 1WRMA 1I9SA 2AZRA 2FH7A 3RGOA 4CVKA 1ONZA 1PTTA 3O4UA 3D1OA 2F6WA 2GP0A 2VTEA 2MBCA 2I6MA 1YGRA 1Q6NA 2QBRA 5LXQB 2CNGA 1NZ7A 3V0DA 2CM2A 2GCAA 3NMEA 2WJPA 2F46A 3D1HA 2HXPA 1FPZA 1G7FA 2E0TA 2BGDA 4HJPA 1C87A 1PXHA 1RXDA 3EU0A 3H2XA 2H04A 2QDMA 4BPCA 2PBNA 3QCJA 4JMJA 2BGEA 3LK7A 4UAGA 1JF7A 1ONYA 2OZ5A 2PI7A 2F6TA 3NRSA 2QDPA 1YPTA 2H4GA 3ZL8A 2I6IA 4R0TA 3UAGA 2JFFA 4OHDA 1MKPA 1NNYA 1NWLA 3N2AA 3F81A 1U26A 1C84A 1BZCA 4WU3A 5GTJA 2R0BA 4HJQA 3QCHA 2CJZA 4NYHA 1ZC0A 3SR9A 2BV5A 3EB1A 2CNEA 3D1QA 1NL9A 2I4HA 2C46A 2PSZA 3F99A 2CNHA 5KABA 3O3LA 2HNPA 2CM3A 2Y96A 4QBEA 2YDUA 4OHLA 5BUGA 2B4UA 2RF6A 1E8CA 2HY3A 3S3KA 4H34A 2VEWA 2B07A 1YZ4A 4BJOA 2F6VA 3ZM1A 4JBCA 1XXPA 2F00A 3QCZA 3QCBA 1C85A 2IMGA 3V0GA 5IBSA 2J17A 3V0EA 3M4UA 2I42A 2UUPA 4RH5A 4D3PA 2Y67A 3ZM2A 4DGXA 3I80A 3GXGA 2WGPA 4ZI4A 2Y1OA 1M3GA 3CWEA 4MBBA 1I57A 2AM1A 1T48A 3PS5A 2NLKA 5KA0A 1P31A 1G1HA 5KADA 2PT0A 1G4US 2CM7A 1Q6SA 1ZZWA 1G1FA 4RI5A 4R0SA 5KA4A 3D42A 1JLNA 4Y2EA 3BLUA 4CVMA 2CM8A 4DGPA 1YTSA 4CVLA 1QZ0A 3V0FA 2HCMA 1BZHA 2I1YA 4RDDA 1XM2A 5BX1A 3AWEA 5KACA 2I3UA 1P15A 1AAXA 2HC2A 1UAGA 1XXVA 4OHEA 4QUNA 3QCNA 1NWEA 2AM2A 2J16B 5KA3A 4PYHA 3ZMQA 4IKCA 3V0IA 2A3KA 2QBSA 1WCHA 1J4XA 4Y14A 3D9CA 2PA5A 1OHEA 3I36A 2M3VA 4ICZA 2Q47A 2HVLA 4C13A 5KA7A 2OC3A 4GE2A 4BUBA 1GQQA 2UUOA 4KYQA 3ZM0A 1FPRA 3V0JA 4KYRA 1PH0A 3BLTA 5EHRA 1YFOA 1A5YA 1G1GA 1OESA 4R30A 3RO1A 3SMEA 3EMUA 3D44A 3GXHA 4QDIA 5K23A 4RH9A 1PTUA 1W78A 3AWGA 2CNFA 5AWXA 1GFYA 1PA9A 3OMHA 3QCDA 1P3DA 4QUMA 3ZMPA 1OEMX 1PA1A 1O5ZA 2CMBA 3A5JA 1E0DA 1J6UA 1LQFA 5HDEA 1L8KA 4AZ1A 3AWFA 1OEUA 2A8BA 4J51A 3V0HA 4GRYA 1C86A 2VEVA 2J16A 1LARA 1FQ1A 1OHCA 1PYNA 2UAGA 1ECVA 2NT7A 3ZV2A 2I5XA 5A5EA 1WAXA 1Q1MA 3ZM5A 4D3RA 3O4TA 5A5FA 1XBOA 4ZRTA 4GRZA 3N0AA 2F6YA 1OHDA 1RPMA 2BIJA 1YTWA 2DXPA 4PVGA 3QCEA 4WOHA 4RKKA 4B04A 2C7SA 2BZLA 1KAVA 2AHSA 1Q6TA 2VEXA 4H1OA 1G4WR 3BM8A 2OOQA 3S3FA 2GC6A 1EEHA 4JMKA 4NX8A 5KA2A 5I6VA 4ZIYA 2Q05A 5K9VA 1U25A 2B49A 1U24A 1BZJA 2CFVA 1C83A 2GJTA 1FGSA 5BZZA 4YR8B 1JBVA 2NTAA 4OHIA 5K22A 1GG4A 4QAPA 4BUCA 3F9AA 2QDCA 4ZN5A 3MMJA 4NWFA 3I7ZA 3EAXA 2F6FA 2B4OA 5KA9A 2Y2FA 1PTYA 3A5KA 5BZXA 3QCMA 1SUGA 4C12A 4S0GA 3PYZA 3QCKA 2GCBA 2JFHA 2QCTA 2X5OA 2Y68A 4GE6A 2QCJA 2H02A 4GFVA 1V3AA 1EENA 2XJAA 4Z6BA 2QBPA 2CMCA 2B4SA 5M43A 5MMZB 3ZM3A 3RGQA 2QEPA 4RI4A 3LJ8A 2GWOA 1C88A 4HV4A 2B3OA 2JJDA 1YTNA 1T4JA 2F70A 2G6ZA 2SHPA 4NWGA 2I75A 2QBQA 1OETA 2CNIA 1G7GA 2FJMA 2NV5A 4NNDA 3QCGA 4TVVA 2I6JA 2H4VA 1T49A 1Q6PA 1QXKA 1NO6A 2F6ZA
chains in the Genus database with same CATH topology
4WU2A 2I6PA 3EZZA 4QAHA 3QCCA 4ERCA 5KA8A 4WTYA 3F9BA 1Q6MA 2HB1A 1GWZA 3QCIA 5IBMA 3CM3A 3O5XA 5K9WA 1YN9A 1OEVA 1YGUA 4GWFA 4KI9A 1YWFA 4GE5A 5K24A 2P6XA 3S4OA 1ZCKA 3RZ2A 4D3QA 3B7OA 3S3HA 1R6HA 3O4SA 4GFUA 3QCFA 2HC1A 1X24A 1LYVA 4QBWA 4JNBA 2VEUA 2ESBA 2H03A 1KAKA 1OEOX 1PTVA 5K25A 3QKPA 2ZMMA 2FJNA 2I6OA 2P4DA 2CMAA 4GS0A 5J8RA 3QCLA 1EEOA 4YAAA 5KAAA 2I4EA 3QKQA 4HRFA 4OHHA 3MOZA 1XRIA 2ZN7A 3BRHA 2PQ5A 2OUDA 2F71A 1I9TA 3S4EA 1Q6JA 2G59A 3OLRA 2NZ6A 4I8NA 2I4GA 2B4PA 1VHRA 3U96A 4RHGA 5EHPA 1D5RA 2VEYA 2H4KA 3S3EA 1L8GA 5KA1A 3MOWA 1ZCLA 2HNQA 3F41A 2NT2A 2I3RA 1WRMA 1I9SA 2AZRA 2FH7A 3RGOA 1ONZA 1PTTA 3O4UA 3D1OA 2F6WA 2GP0A 2MBCA 2I6MA 1YGRA 1Q6NA 2QBRA 5LXQB 2CNGA 1NZ7A 3V0DA 2CM2A 3NMEA 2F46A 3D1HA 2HXPA 1FPZA 1G7FA 2E0TA 2BGDA 4HJPA 1C87A 1PXHA 1RXDA 3EU0A 3H2XA 2H04A 2QDMA 4BPCA 2PBNA 3QCJA 4JMJA 2BGEA 1JF7A 1ONYA 2OZ5A 2PI7A 2F6TA 2QDPA 1YPTA 2H4GA 2I6IA 4R0TA 4OHDA 1MKPA 1NNYA 1NWLA 3F81A 1U26A 1C84A 1BZCA 4WU3A 5GTJA 2R0BA 4HJQA 3QCHA 2CJZA 4NYHA 1ZC0A 3SR9A 2BV5A 3EB1A 2CNEA 3D1QA 1NL9A 2I4HA 2C46A 2PSZA 3F99A 2CNHA 5KABA 3O3LA 2HNPA 2CM3A 2Y96A 4QBEA 2YDUA 4OHLA 5BUGA 2B4UA 2RF6A 2HY3A 3S3KA 4H34A 2VEWA 2B07A 1YZ4A 4BJOA 2F6VA 3ZM1A 4JBCA 1XXPA 3QCBA 1C85A 2IMGA 3V0GA 5IBSA 2J17A 3V0EA 3M4UA 2I42A 4RH5A 4D3PA 3ZM2A 4DGXA 3I80A 3GXGA 2WGPA 4ZI4A 1M3GA 3CWEA 4MBBA 1I57A 1T48A 3PS5A 2NLKA 5KA0A 5KADA 1G1HA 2PT0A 1G4US 2CM7A 1Q6SA 1ZZWA 1G1FA 4RI5A 4R0SA 5KA4A 3D42A 1JLNA 4Y2EA 3BLUA 2CM8A 4DGPA 1YTSA 1QZ0A 3V0FA 2HCMA 1BZHA 2I1YA 4RDDA 1XM2A 5BX1A 3AWEA 5KACA 2I3UA 1P15A 1AAXA 2HC2A 1XXVA 4OHEA 4QUNA 3QCNA 1NWEA 2J16B 5KA3A 4PYHA 3ZMQA 4IKCA 3V0IA 2A3KA 2QBSA 1WCHA 1J4XA 4Y14A 3D9CA 2PA5A 1OHEA 3I36A 2M3VA 4ICZA 2Q47A 2HVLA 5KA7A 2OC3A 4GE2A 4KYQA 3ZM0A 1FPRA 3V0JA 4KYRA 1PH0A 3BLTA 5EHRA 1YFOA 1A5YA 1G1GA 1OESA 4R30A 3RO1A 3SMEA 3EMUA 3D44A 3GXHA 5K23A 4RH9A 1PTUA 3AWGA 2CNFA 5AWXA 1GFYA 1PA9A 3OMHA 3QCDA 4QUMA 3ZMPA 1OEMX 1PA1A 2CMBA 3A5JA 1LQFA 5HDEA 1L8KA 4AZ1A 3AWFA 1OEUA 2A8BA 4J51A 3V0HA 4GRYA 1C86A 2VEVA 2J16A 1LARA 1FQ1A 1OHCA 1PYNA 1ECVA 2NT7A 3ZV2A 2I5XA 1WAXA 1Q1MA 4D3RA 3O4TA 1XBOA 4ZRTA 4GRZA 3N0AA 2F6YA 1OHDA 1RPMA 2BIJA 1YTWA 2DXPA 4PVGA 3QCEA 4WOHA 4RKKA 4B04A 2C7SA 2BZLA 1KAVA 2AHSA 1Q6TA 2VEXA 4H1OA 1G4WR 3BM8A 2OOQA 3S3FA 4JMKA 4NX8A 5KA2A 5I6VA 2Q05A 5K9VA 1U25A 2B49A 1U24A 1BZJA 2CFVA 1C83A 2GJTA 5BZZA 4YR8B 2NTAA 4OHIA 5K22A 4QAPA 3F9AA 2QDCA 4ZN5A 3MMJA 4NWFA 3I7ZA 3EAXA 2F6FA 2B4OA 5KA9A 2Y2FA 1PTYA 3A5KA 5BZXA 3QCMA 1SUGA 4S0GA 3QCKA 2QCTA 4GE6A 2QCJA 2H02A 4GFVA 1V3AA 1EENA 4Z6BA 2QBPA 2CMCA 2B4SA 5M43A 5MMZB 3ZM3A 3RGQA 2QEPA 4RI4A 3LJ8A 2GWOA 1C88A 2B3OA 2JJDA 1YTNA 1T4JA 2F70A 2G6ZA 2SHPA 4NWGA 2I75A 2QBQA 1OETA 2CNIA 1G7GA 2FJMA 2NV5A 4NNDA 3QCGA 4TVVA 2I6JA 2H4VA 1T49A 1Q6PA 1QXKA 1NO6A 2F6ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WU2 A;  2I6P A;  3EZZ A;  4QAH A;  3QCC A;  4ERC A;  5KA8 A;  4WTY A;  3F9B A;  1Q6M A;  2HB1 A;  1GWZ A;  3QCI A;  5IBM A;  3CM3 A;  3O5X A;  5K9W A;  1YN9 A;  1OEV A;  1YGU A;  4GWF A;  4KI9 A;  1YWF A;  4GE5 A;  5K24 A;  2P6X A;  3S4O A;  1ZCK A;  3RZ2 A;  4D3Q A;  3B7O A;  3S3H A;  1R6H A;  3O4S A;  4GFU A;  3QCF A;  2HC1 A;  1X24 A;  1LYV A;  4QBW A;  4JNB A;  2VEU A;  2ESB A;  2H03 A;  1KAK A;  1OEO X;  1PTV A;  5K25 A;  3QKP A;  2ZMM A;  2FJN A;  2I6O A;  2P4D A;  2CMA A;  4GS0 A;  5J8R A;  3QCL A;  1EEO A;  4YAA A;  5KAA A;  2I4E A;  3QKQ A;  4HRF A;  4OHH A;  3MOZ A;  1XRI A;  2ZN7 A;  3BRH A;  2PQ5 A;  2OUD A;  2F71 A;  1I9T A;  3S4E A;  1Q6J A;  2G59 A;  3OLR A;  2NZ6 A;  4I8N A;  2I4G A;  2B4P A;  1VHR A;  3U96 A;  4RHG A;  5EHP A;  1D5R A;  2VEY A;  2H4K A;  3S3E A;  1L8G A;  5KA1 A;  3MOW A;  1ZCL A;  2HNQ A;  3F41 A;  2NT2 A;  2I3R A;  1WRM A;  1I9S A;  2AZR A;  2FH7 A;  3RGO A;  1ONZ A;  1PTT A;  3O4U A;  3D1O A;  2F6W A;  2GP0 A;  2MBC A;  2I6M A;  1YGR A;  1Q6N A;  2QBR A;  5LXQ B;  2CNG A;  1NZ7 A;  3V0D A;  2CM2 A;  3NME A;  2F46 A;  3D1H A;  2HXP A;  1FPZ A;  1G7F A;  2E0T A;  2BGD A;  4HJP A;  1C87 A;  1PXH A;  1RXD A;  3EU0 A;  3H2X A;  2H04 A;  2QDM A;  4BPC A;  2PBN A;  3QCJ A;  4JMJ A;  2BGE A;  1JF7 A;  1ONY A;  2OZ5 A;  2PI7 A;  2F6T A;  2QDP A;  1YPT A;  2H4G A;  2I6I A;  4R0T A;  4OHD A;  1MKP A;  1NNY A;  1NWL A;  3F81 A;  1U26 A;  1C84 A;  1BZC A;  4WU3 A;  5GTJ A;  2R0B A;  4HJQ A;  3QCH A;  2CJZ A;  4NYH A;  1ZC0 A;  3SR9 A;  2BV5 A;  3EB1 A;  2CNE A;  3D1Q A;  1NL9 A;  2I4H A;  2C46 A;  2PSZ A;  3F99 A;  2CNH A;  5KAB A;  3O3L A;  2HNP A;  2CM3 A;  2Y96 A;  4QBE A;  2YDU A;  4OHL A;  5BUG A;  2B4U A;  2RF6 A;  2HY3 A;  3S3K A;  4H34 A;  2VEW A;  2B07 A;  1YZ4 A;  4BJO A;  2F6V A;  3ZM1 A;  4JBC A;  1XXP A;  3QCB A;  1C85 A;  2IMG A;  3V0G A;  5IBS A;  2J17 A;  3V0E A;  3M4U A;  2I42 A;  4RH5 A;  4D3P A;  3ZM2 A;  4DGX A;  3I80 A;  3GXG A;  2WGP A;  4ZI4 A;  1M3G A;  3CWE A;  4MBB A;  1I57 A;  1T48 A;  3PS5 A;  2NLK A;  5KA0 A;  5KAD A;  1G1H A;  2PT0 A;  1G4U S;  2CM7 A;  1Q6S A;  1ZZW A;  1G1F A;  4RI5 A;  4R0S A;  5KA4 A;  3D42 A;  1JLN A;  4Y2E A;  3BLU A;  2CM8 A;  4DGP A;  1YTS A;  1QZ0 A;  3V0F A;  2HCM A;  1BZH A;  2I1Y A;  4RDD A;  1XM2 A;  5BX1 A;  3AWE A;  5KAC A;  2I3U A;  1P15 A;  1AAX A;  2HC2 A;  1XXV A;  4OHE A;  4QUN A;  3QCN A;  1NWE A;  2J16 B;  5KA3 A;  4PYH A;  3ZMQ A;  4IKC A;  3V0I A;  2A3K A;  2QBS A;  1WCH A;  1J4X A;  4Y14 A;  3D9C A;  2PA5 A;  1OHE A;  3I36 A;  2M3V A;  4ICZ A;  2Q47 A;  2HVL A;  5KA7 A;  2OC3 A;  4GE2 A;  4KYQ A;  3ZM0 A;  1FPR A;  3V0J A;  4KYR A;  1PH0 A;  3BLT A;  5EHR A;  1YFO A;  1A5Y A;  1G1G A;  1OES A;  4R30 A;  3RO1 A;  3SME A;  3EMU A;  3D44 A;  3GXH A;  5K23 A;  4RH9 A;  1PTU A;  3AWG A;  2CNF A;  5AWX A;  1GFY A;  1PA9 A;  3OMH A;  3QCD A;  4QUM A;  3ZMP A;  1OEM X;  1PA1 A;  2CMB A;  3A5J A;  1LQF A;  5HDE A;  1L8K A;  4AZ1 A;  3AWF A;  1OEU A;  2A8B A;  4J51 A;  3V0H A;  4GRY A;  1C86 A;  2VEV A;  2J16 A;  1LAR A;  1FQ1 A;  1OHC A;  1PYN A;  1ECV A;  2NT7 A;  3ZV2 A;  2I5X A;  1WAX A;  1Q1M A;  4D3R A;  3O4T A;  1XBO A;  4ZRT A;  4GRZ A;  3N0A A;  2F6Y A;  1OHD A;  1RPM A;  2BIJ A;  1YTW A;  2DXP A;  4PVG A;  3QCE A;  4WOH A;  4RKK A;  4B04 A;  2C7S A;  2BZL A;  1KAV A;  2AHS A;  1Q6T A;  2VEX A;  4H1O A;  1G4W R;  3BM8 A;  2OOQ A;  3S3F A;  4JMK A;  4NX8 A;  5KA2 A;  5I6V A;  2Q05 A;  5K9V A;  1U25 A;  2B49 A;  1U24 A;  1BZJ A;  2CFV A;  1C83 A;  2GJT A;  5BZZ A;  4YR8 B;  2NTA A;  4OHI A;  5K22 A;  4QAP A;  3F9A A;  2QDC A;  4ZN5 A;  3MMJ A;  4NWF A;  3I7Z A;  3EAX A;  2F6F A;  2B4O A;  5KA9 A;  2Y2F A;  1PTY A;  3A5K A;  5BZX A;  3QCM A;  1SUG A;  4S0G A;  3QCK A;  2QCT A;  4GE6 A;  2QCJ A;  2H02 A;  4GFV A;  1V3A A;  1EEN A;  4Z6B A;  2QBP A;  2CMC A;  2B4S A;  5M43 A;  5MMZ B;  3ZM3 A;  3RGQ A;  2QEP A;  4RI4 A;  3LJ8 A;  2GWO A;  1C88 A;  2B3O A;  2JJD A;  1YTN A;  1T4J A;  2F70 A;  2G6Z A;  2SHP A;  4NWG A;  2I75 A;  2QBQ A;  1OET A;  2CNI A;  1G7G A;  2FJM A;  2NV5 A;  4NND A;  3QCG A;  4TVV A;  2I6J A;  2H4V A;  1T49 A;  1Q6P A;  1QXK A;  1NO6 A;  2F6Z A; 
#chains in the Genus database with same CATH topology
 4WU2 A;  2I6P A;  3EZZ A;  4QAH A;  3QCC A;  2XPC A;  4ERC A;  5KA8 A;  4WTY A;  3F9B A;  1Q6M A;  2HB1 A;  1GWZ A;  3QCI A;  1JBW A;  5IBM A;  3CM3 A;  3O5X A;  5K9W A;  1YN9 A;  1OEV A;  3HN7 A;  1YGU A;  2VOR A;  2Y66 A;  4GWF A;  4KI9 A;  1YWF A;  4GE5 A;  5K24 A;  2P6X A;  3ZM6 A;  3S4O A;  1ZCK A;  3RZ2 A;  4D3Q A;  3B7O A;  3S3H A;  1R6H A;  3O4S A;  4GFU A;  1GQY A;  3QCF A;  2HC1 A;  2VOS A;  1X24 A;  1LYV A;  4QBW A;  4JNB A;  2VEU A;  2ESB A;  2H03 A;  1KAK A;  1OEO X;  1PTV A;  2GC5 A;  5K25 A;  3QKP A;  2ZMM A;  2FJN A;  4QF5 A;  2I6O A;  2P4D A;  2CMA A;  4GS0 A;  5J8R A;  3QCL A;  1EEO A;  4YAA A;  5KAA A;  2I4E A;  3QKQ A;  4HRF A;  3MVN A;  4OHH A;  3MOZ A;  1XRI A;  2ZN7 A;  2WTZ A;  3BRH A;  2PQ5 A;  2OUD A;  2F71 A;  1I9T A;  3S4E A;  1Q6J A;  2G59 A;  3OLR A;  1W7K A;  2NZ6 A;  4I8N A;  2I4G A;  2B4P A;  1VHR A;  3U96 A;  4RHG A;  5EHP A;  1D5R A;  2VEY A;  2VTD A;  2JFG A;  2H4K A;  3S3E A;  1L8G A;  5KA1 A;  3MOW A;  1ZCL A;  2HNQ A;  3F41 A;  2NT2 A;  2I3R A;  1WRM A;  1I9S A;  2AZR A;  2FH7 A;  3RGO A;  4CVK A;  1ONZ A;  1PTT A;  3O4U A;  3D1O A;  2F6W A;  2GP0 A;  2VTE A;  2MBC A;  2I6M A;  1YGR A;  1Q6N A;  2QBR A;  5LXQ B;  2CNG A;  1NZ7 A;  3V0D A;  2CM2 A;  2GCA A;  3NME A;  2WJP A;  2F46 A;  3D1H A;  2HXP A;  1FPZ A;  1G7F A;  2E0T A;  2BGD A;  4HJP A;  1C87 A;  1PXH A;  1RXD A;  3EU0 A;  3H2X A;  2H04 A;  2QDM A;  4BPC A;  2PBN A;  3QCJ A;  4JMJ A;  2BGE A;  3LK7 A;  4UAG A;  1JF7 A;  1ONY A;  2OZ5 A;  2PI7 A;  2F6T A;  3NRS A;  2QDP A;  1YPT A;  2H4G A;  3ZL8 A;  2I6I A;  4R0T A;  3UAG A;  2JFF A;  4OHD A;  1MKP A;  1NNY A;  1NWL A;  3N2A A;  3F81 A;  1U26 A;  1C84 A;  1BZC A;  4WU3 A;  5GTJ A;  2R0B A;  4HJQ A;  3QCH A;  2CJZ A;  4NYH A;  1ZC0 A;  3SR9 A;  2BV5 A;  3EB1 A;  2CNE A;  3D1Q A;  1NL9 A;  2I4H A;  2C46 A;  2PSZ A;  3F99 A;  2CNH A;  5KAB A;  3O3L A;  2HNP A;  2CM3 A;  2Y96 A;  4QBE A;  2YDU A;  4OHL A;  5BUG A;  2B4U A;  2RF6 A;  1E8C A;  2HY3 A;  3S3K A;  4H34 A;  2VEW A;  2B07 A;  1YZ4 A;  4BJO A;  2F6V A;  3ZM1 A;  4JBC A;  1XXP A;  2F00 A;  3QCZ A;  3QCB A;  1C85 A;  2IMG A;  3V0G A;  5IBS A;  2J17 A;  3V0E A;  3M4U A;  2I42 A;  2UUP A;  4RH5 A;  4D3P A;  2Y67 A;  3ZM2 A;  4DGX A;  3I80 A;  3GXG A;  2WGP A;  4ZI4 A;  2Y1O A;  1M3G A;  3CWE A;  4MBB A;  1I57 A;  2AM1 A;  1T48 A;  3PS5 A;  2NLK A;  5KA0 A;  1P31 A;  1G1H A;  5KAD A;  2PT0 A;  1G4U S;  2CM7 A;  1Q6S A;  1ZZW A;  1G1F A;  4RI5 A;  4R0S A;  5KA4 A;  3D42 A;  1JLN A;  4Y2E A;  3BLU A;  4CVM A;  2CM8 A;  4DGP A;  1YTS A;  4CVL A;  1QZ0 A;  3V0F A;  2HCM A;  1BZH A;  2I1Y A;  4RDD A;  1XM2 A;  5BX1 A;  3AWE A;  5KAC A;  2I3U A;  1P15 A;  1AAX A;  2HC2 A;  1UAG A;  1XXV A;  4OHE A;  4QUN A;  3QCN A;  1NWE A;  2AM2 A;  2J16 B;  5KA3 A;  4PYH A;  3ZMQ A;  4IKC A;  3V0I A;  2A3K A;  2QBS A;  1WCH A;  1J4X A;  4Y14 A;  3D9C A;  2PA5 A;  1OHE A;  3I36 A;  2M3V A;  4ICZ A;  2Q47 A;  2HVL A;  4C13 A;  5KA7 A;  2OC3 A;  4GE2 A;  4BUB A;  1GQQ A;  2UUO A;  4KYQ A;  3ZM0 A;  1FPR A;  3V0J A;  4KYR A;  1PH0 A;  3BLT A;  5EHR A;  1YFO A;  1A5Y A;  1G1G A;  1OES A;  4R30 A;  3RO1 A;  3SME A;  3EMU A;  3D44 A;  3GXH A;  4QDI A;  5K23 A;  4RH9 A;  1PTU A;  1W78 A;  3AWG A;  2CNF A;  5AWX A;  1GFY A;  1PA9 A;  3OMH A;  3QCD A;  1P3D A;  4QUM A;  3ZMP A;  1OEM X;  1PA1 A;  1O5Z A;  2CMB A;  3A5J A;  1E0D A;  1J6U A;  1LQF A;  5HDE A;  1L8K A;  4AZ1 A;  3AWF A;  1OEU A;  2A8B A;  4J51 A;  3V0H A;  4GRY A;  1C86 A;  2VEV A;  2J16 A;  1LAR A;  1FQ1 A;  1OHC A;  1PYN A;  2UAG A;  1ECV A;  2NT7 A;  3ZV2 A;  2I5X A;  5A5E A;  1WAX A;  1Q1M A;  3ZM5 A;  4D3R A;  3O4T A;  5A5F A;  1XBO A;  4ZRT A;  4GRZ A;  3N0A A;  2F6Y A;  1OHD A;  1RPM A;  2BIJ A;  1YTW A;  2DXP A;  4PVG A;  3QCE A;  4WOH A;  4RKK A;  4B04 A;  2C7S A;  2BZL A;  1KAV A;  2AHS A;  1Q6T A;  2VEX A;  4H1O A;  1G4W R;  3BM8 A;  2OOQ A;  3S3F A;  2GC6 A;  1EEH A;  4JMK A;  4NX8 A;  5KA2 A;  5I6V A;  4ZIY A;  2Q05 A;  5K9V A;  1U25 A;  2B49 A;  1U24 A;  1BZJ A;  2CFV A;  1C83 A;  2GJT A;  1FGS A;  5BZZ A;  4YR8 B;  1JBV A;  2NTA A;  4OHI A;  5K22 A;  1GG4 A;  4QAP A;  4BUC A;  3F9A A;  2QDC A;  4ZN5 A;  3MMJ A;  4NWF A;  3I7Z A;  3EAX A;  2F6F A;  2B4O A;  5KA9 A;  2Y2F A;  1PTY A;  3A5K A;  5BZX A;  3QCM A;  1SUG A;  4C12 A;  4S0G A;  3PYZ A;  3QCK A;  2GCB A;  2JFH A;  2QCT A;  2X5O A;  2Y68 A;  4GE6 A;  2QCJ A;  2H02 A;  4GFV A;  1V3A A;  1EEN A;  2XJA A;  4Z6B A;  2QBP A;  2CMC A;  2B4S A;  5M43 A;  5MMZ B;  3ZM3 A;  3RGQ A;  2QEP A;  4RI4 A;  3LJ8 A;  2GWO A;  1C88 A;  4HV4 A;  2B3O A;  2JJD A;  1YTN A;  1T4J A;  2F70 A;  2G6Z A;  2SHP A;  4NWG A;  2I75 A;  2QBQ A;  1OET A;  2CNI A;  1G7G A;  2FJM A;  2NV5 A;  4NND A;  3QCG A;  4TVV A;  2I6J A;  2H4V A;  1T49 A;  1Q6P A;  1QXK A;  1NO6 A;  2F6Z A; 
#chains in the Genus database with same CATH homology
 4WU2 A;  2I6P A;  3EZZ A;  4QAH A;  3QCC A;  4ERC A;  5KA8 A;  4WTY A;  3F9B A;  1Q6M A;  2HB1 A;  1GWZ A;  3QCI A;  5IBM A;  3CM3 A;  3O5X A;  5K9W A;  1YN9 A;  1OEV A;  1YGU A;  4GWF A;  4KI9 A;  1YWF A;  4GE5 A;  5K24 A;  2P6X A;  3S4O A;  1ZCK A;  3RZ2 A;  4D3Q A;  3B7O A;  3S3H A;  1R6H A;  3O4S A;  4GFU A;  3QCF A;  2HC1 A;  1X24 A;  1LYV A;  4QBW A;  4JNB A;  2VEU A;  2ESB A;  2H03 A;  1KAK A;  1OEO X;  1PTV A;  5K25 A;  3QKP A;  2ZMM A;  2FJN A;  2I6O A;  2P4D A;  2CMA A;  4GS0 A;  5J8R A;  3QCL A;  1EEO A;  4YAA A;  5KAA A;  2I4E A;  3QKQ A;  4HRF A;  4OHH A;  3MOZ A;  1XRI A;  2ZN7 A;  3BRH A;  2PQ5 A;  2OUD A;  2F71 A;  1I9T A;  3S4E A;  1Q6J A;  2G59 A;  3OLR A;  2NZ6 A;  4I8N A;  2I4G A;  2B4P A;  1VHR A;  3U96 A;  4RHG A;  5EHP A;  1D5R A;  2VEY A;  2H4K A;  3S3E A;  1L8G A;  5KA1 A;  3MOW A;  1ZCL A;  2HNQ A;  3F41 A;  2NT2 A;  2I3R A;  1WRM A;  1I9S A;  2AZR A;  2FH7 A;  3RGO A;  1ONZ A;  1PTT A;  3O4U A;  3D1O A;  2F6W A;  2GP0 A;  2MBC A;  2I6M A;  1YGR A;  1Q6N A;  2QBR A;  5LXQ B;  2CNG A;  1NZ7 A;  3V0D A;  2CM2 A;  3NME A;  2F46 A;  3D1H A;  2HXP A;  1FPZ A;  1G7F A;  2E0T A;  2BGD A;  4HJP A;  1C87 A;  1PXH A;  1RXD A;  3EU0 A;  3H2X A;  2H04 A;  2QDM A;  4BPC A;  2PBN A;  3QCJ A;  4JMJ A;  2BGE A;  1JF7 A;  1ONY A;  2OZ5 A;  2PI7 A;  2F6T A;  2QDP A;  1YPT A;  2H4G A;  2I6I A;  4R0T A;  4OHD A;  1MKP A;  1NNY A;  1NWL A;  3F81 A;  1U26 A;  1C84 A;  1BZC A;  4WU3 A;  5GTJ A;  2R0B A;  4HJQ A;  3QCH A;  2CJZ A;  4NYH A;  1ZC0 A;  3SR9 A;  2BV5 A;  3EB1 A;  2CNE A;  3D1Q A;  1NL9 A;  2I4H A;  2C46 A;  2PSZ A;  3F99 A;  2CNH A;  5KAB A;  3O3L A;  2HNP A;  2CM3 A;  2Y96 A;  4QBE A;  2YDU A;  4OHL A;  5BUG A;  2B4U A;  2RF6 A;  2HY3 A;  3S3K A;  4H34 A;  2VEW A;  2B07 A;  1YZ4 A;  4BJO A;  2F6V A;  3ZM1 A;  4JBC A;  1XXP A;  3QCB A;  1C85 A;  2IMG A;  3V0G A;  5IBS A;  2J17 A;  3V0E A;  3M4U A;  2I42 A;  4RH5 A;  4D3P A;  3ZM2 A;  4DGX A;  3I80 A;  3GXG A;  2WGP A;  4ZI4 A;  1M3G A;  3CWE A;  4MBB A;  1I57 A;  1T48 A;  3PS5 A;  2NLK A;  5KA0 A;  5KAD A;  1G1H A;  2PT0 A;  1G4U S;  2CM7 A;  1Q6S A;  1ZZW A;  1G1F A;  4RI5 A;  4R0S A;  5KA4 A;  3D42 A;  1JLN A;  4Y2E A;  3BLU A;  2CM8 A;  4DGP A;  1YTS A;  1QZ0 A;  3V0F A;  2HCM A;  1BZH A;  2I1Y A;  4RDD A;  1XM2 A;  5BX1 A;  3AWE A;  5KAC A;  2I3U A;  1P15 A;  1AAX A;  2HC2 A;  1XXV A;  4OHE A;  4QUN A;  3QCN A;  1NWE A;  2J16 B;  5KA3 A;  4PYH A;  3ZMQ A;  4IKC A;  3V0I A;  2A3K A;  2QBS A;  1WCH A;  1J4X A;  4Y14 A;  3D9C A;  2PA5 A;  1OHE A;  3I36 A;  2M3V A;  4ICZ A;  2Q47 A;  2HVL A;  5KA7 A;  2OC3 A;  4GE2 A;  4KYQ A;  3ZM0 A;  1FPR A;  3V0J A;  4KYR A;  1PH0 A;  3BLT A;  5EHR A;  1YFO A;  1A5Y A;  1G1G A;  1OES A;  4R30 A;  3RO1 A;  3SME A;  3EMU A;  3D44 A;  3GXH A;  5K23 A;  4RH9 A;  1PTU A;  3AWG A;  2CNF A;  5AWX A;  1GFY A;  1PA9 A;  3OMH A;  3QCD A;  4QUM A;  3ZMP A;  1OEM X;  1PA1 A;  2CMB A;  3A5J A;  1LQF A;  5HDE A;  1L8K A;  4AZ1 A;  3AWF A;  1OEU A;  2A8B A;  4J51 A;  3V0H A;  4GRY A;  1C86 A;  2VEV A;  2J16 A;  1LAR A;  1FQ1 A;  1OHC A;  1PYN A;  1ECV A;  2NT7 A;  3ZV2 A;  2I5X A;  1WAX A;  1Q1M A;  4D3R A;  3O4T A;  1XBO A;  4ZRT A;  4GRZ A;  3N0A A;  2F6Y A;  1OHD A;  1RPM A;  2BIJ A;  1YTW A;  2DXP A;  4PVG A;  3QCE A;  4WOH A;  4RKK A;  4B04 A;  2C7S A;  2BZL A;  1KAV A;  2AHS A;  1Q6T A;  2VEX A;  4H1O A;  1G4W R;  3BM8 A;  2OOQ A;  3S3F A;  4JMK A;  4NX8 A;  5KA2 A;  5I6V A;  2Q05 A;  5K9V A;  1U25 A;  2B49 A;  1U24 A;  1BZJ A;  2CFV A;  1C83 A;  2GJT A;  5BZZ A;  4YR8 B;  2NTA A;  4OHI A;  5K22 A;  4QAP A;  3F9A A;  2QDC A;  4ZN5 A;  3MMJ A;  4NWF A;  3I7Z A;  3EAX A;  2F6F A;  2B4O A;  5KA9 A;  2Y2F A;  1PTY A;  3A5K A;  5BZX A;  3QCM A;  1SUG A;  4S0G A;  3QCK A;  2QCT A;  4GE6 A;  2QCJ A;  2H02 A;  4GFV A;  1V3A A;  1EEN A;  4Z6B A;  2QBP A;  2CMC A;  2B4S A;  5M43 A;  5MMZ B;  3ZM3 A;  3RGQ A;  2QEP A;  4RI4 A;  3LJ8 A;  2GWO A;  1C88 A;  2B3O A;  2JJD A;  1YTN A;  1T4J A;  2F70 A;  2G6Z A;  2SHP A;  4NWG A;  2I75 A;  2QBQ A;  1OET A;  2CNI A;  1G7G A;  2FJM A;  2NV5 A;  4NND A;  3QCG A;  4TVV A;  2I6J A;  2H4V A;  1T49 A;  1Q6P A;  1QXK A;  1NO6 A;  2F6Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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