1T48A

Allosteric inhibition of protein tyrosine phosphatase 1b
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
298
structure length
292
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Allosteric inhibition of protein tyrosine phosphatase 1B
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein-tyrosine phosphatase, non-receptor type 1
total genus 96
structure length 292
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2004-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1t48A00
2PBNA 1OHEA 2H4GA 3O4TA 1QZ0A 1EEOA 1G7GA 4JBCA 4WTYA 2QDMA 4RDDA 1ECVA 1SUGA 1U25A 1C84A 2DXPA 4DGPA 2BIJA 2I6JA 2PSZA 1LARA 2F70A 2I3UA 1Q6TA 4PYHA 5I6VA 4GRZA 1VHRA 2I6OA 5M43A 1GFYA 2PT0A 2SHPA 5KABA 2CM2A 3RGOA 1YWFA 1G1GA 4D3RA 5IBSA 5EHPA 2ZMMA 3CWEA 3QCIA 4R30A 3SR9A 4DGXA 3F9BA 1G4US 3SMEA 2YDUA 5KACA 4ICZA 4NNDA 3QCEA 4RI5A 1ONZA 2VEYA 2HB1A 2QEPA 4JNBA 4QBEA 3AWEA 1YGUA 2I1YA 2I4GA 2I75A 3RO1A 2F6FA 1C85A 3QCKA 1Q1MA 2NV5A 2QCJA 5HDEA 1NWEA 4ERCA 1G4WR 1P15A 2VEWA 3QCJA 1QXKA 4KI9A 1PH0A 4JMKA 2QBQA 2F6ZA 3V0IA 1WRMA 2VEUA 1NL9A 2CMAA 2QCTA 1ZZWA 1YTWA 3OMHA 3QCHA 4ZN5A 1FQ1A 4IKCA 1Q6PA 4WU3A 1L8KA 1PTUA 3RZ2A 2CM7A 2I4EA 1L8GA 4HJQA 4RI4A 2F6YA 2NTAA 2QBRA 3QCCA 4Z6BA 3O3LA 2F6TA 4GS0A 2GJTA 3F81A 3N0AA 4D3QA 1I57A 2H03A 2H4VA 3MOWA 2OOQA 4RKKA 5K25A 2PQ5A 2FJMA 3GXGA 3BRHA 4QUNA 4NWFA 4WOHA 3I80A 3AWFA 2G59A 2E0TA 5K9WA 2OUDA 1NO6A 5KA9A 5KA1A 5K22A 1V3AA 2AHSA 4GFUA 3QCGA 4PVGA 2F6WA 3V0GA 2IMGA 3O4UA 1I9TA 2I3RA 2HNPA 1C87A 1PTYA 4QBWA 4KYQA 4ZI4A 4Y2EA 4QAHA 5K23A 1WAXA 3ZM3A 3S3FA 1BZJA 1LQFA 3RGQA 1T4JA 2PA5A 2F46A 5KA8A 1BZCA 2C7SA 5KAAA 2NLKA 1NZ7A 2I4HA 3ZMPA 1Q6SA 2HC1A 3S3EA 2CNGA 2QBPA 5KA4A 2I6MA 2OZ5A 1PYNA 2A8BA 4BPCA 1WCHA 3ZM0A 4OHHA 1NWLA 3D9CA 3O4SA 1FPZA 1OEUA 5KADA 1LYVA 4J51A 1PTTA 3QKPA 4OHLA 3LJ8A 2BV5A 4HRFA 5IBMA 1ZC0A 3I36A 4I8NA 1KAVA 3V0FA 4RH5A 1YN9A 2F6VA 2I6PA 1ONYA 4OHEA 1A5YA 2R0BA 2BGEA 2HY3A 1C88A 2J16B 5MMZB 4OHIA 4GRYA 2CMBA 2QDCA 2HXPA 2Y96A 2CM3A 3QCFA 3I7ZA 1YPTA 2CMCA 1X24A 5J8RA 2F71A 4H1OA 4RHGA 3EMUA 5K9VA 1GWZA 3M4UA 3H2XA 2NZ6A 4Y14A 3QCBA 2G6ZA 2CFVA 1Q6JA 2B3OA 2CNEA 2M3VA 3GXHA 1G1HA 3O5XA 2I5XA 4WU2A 2CNIA 1JLNA 3EU0A 3ZMQA 1ZCLA 1YTNA 2CM8A 2PI7A 2WGPA 2Q05A 2AZRA 2OC3A 1OHDA 2HVLA 5EHRA 3NMEA 1XM2A 1YTSA 3V0JA 2P4DA 1U24A 5AWXA 1RXDA 5BZXA 5LXQB 4ZRTA 3ZV2A 2RF6A 1YFOA 1R6HA 4AZ1A 2QBSA 3A5KA 3AWGA 2BGDA 2CJZA 2FH7A 3EZZA 3QCDA 4BJOA 3QKQA 3EB1A 2ZN7A 1NNYA 4GE5A 3D1OA 5GTJA 1OHCA 1T49A 5KA2A 5KA7A 1OEMX 4GE2A 4R0SA 5K24A 4JMJA 1G7FA 3MOZA 2VEVA 4GE6A 2A3KA 2H02A 2GWOA 5BZZA 4YR8B 3S4EA 1RPMA 5BX1A 1C86A 1PXHA 3ZM1A 2HNQA 1G1FA 2H4KA 1I9SA 2J17A 2I6IA 2MBCA 3BLTA 3BLUA 2BZLA 3ZM2A 1OESA 4OHDA 1OETA 3BM8A 3A5JA 3OLRA 4B04A 1Q6MA 3MMJA 4GWFA 4MBBA 1Q6NA 4HJPA 2H04A 1OEOX 2CNHA 2I42A 3V0HA 1AAXA 3V0DA 2FJNA 3PS5A 3D44A 1M3GA 2GP0A 1U26A 2HCMA 2CNFA 2B07A 4NX8A 1OEVA 3S3KA 2HC2A 1XRIA 3F99A 3QCMA 4QUMA 2Q47A 3EAXA 3U96A 1YGRA 2B4PA 3QCLA 1C83A 3B7OA 2B4UA 2NT2A 1XXPA 1MKPA 1XXVA 4NWGA 1J4XA 1JF7A 4H34A 1PTVA 2P6XA 2B4SA 5KA3A 1ZCKA 4KYRA 1FPRA 2ESBA 1XBOA 2VEXA 3D42A 4S0GA 1T48A 1BZHA 1D5RA 3QCNA 1PA9A 2C46A 3F9AA 3V0EA 1KAKA 2Y2FA 3S3HA 2B4OA 3CM3A 2NT7A 5BUGA 3F41A 2J16A 4RH9A 2QDPA 1EENA 3D1HA 1YZ4A 4NYHA 1PA1A 3S4OA 5KA0A 4QAPA 2JJDA 4GFVA 4R0TA 4TVVA 4YAAA 3D1QA 2B49A 4D3PA
chains in the Genus database with same CATH superfamily
2PBNA 1OHEA 2H4GA 3O4TA 1QZ0A 1EEOA 1G7GA 1P3DA 4JBCA 4WTYA 2QDMA 4RDDA 4ZIYA 1ECVA 1SUGA 1U25A 1C84A 2DXPA 2F00A 4DGPA 2BIJA 4QF5A 2I6JA 2PSZA 1LARA 2F70A 2I3UA 1Q6TA 4PYHA 1GQQA 5I6VA 4GRZA 1VHRA 2I6OA 5M43A 1GFYA 2PT0A 2SHPA 2VTEA 5KABA 2CM2A 3RGOA 1YWFA 1G1GA 4D3RA 5IBSA 5EHPA 2ZMMA 3CWEA 3QCIA 4R30A 3SR9A 4DGXA 3F9BA 1G4US 3SMEA 2YDUA 1W78A 5KACA 4ICZA 1O5ZA 1UAGA 4NNDA 3ZL8A 3QCEA 4RI5A 1ONZA 2VEYA 2HB1A 2QEPA 3PYZA 4JNBA 4QBEA 3AWEA 1YGUA 2I1YA 1J6UA 1E0DA 2I4GA 2I75A 3RO1A 2F6FA 1C85A 2NV5A 2QCJA 1Q1MA 2GCAA 3QCKA 5HDEA 1NWEA 4ERCA 1G4WR 1P15A 2VEWA 3QCJA 1QXKA 4KI9A 1PH0A 4JMKA 1JBWA 2QBQA 2F6ZA 3V0IA 2AM2A 1WRMA 4C12A 2VEUA 1NL9A 2CMAA 2QCTA 1ZZWA 1YTWA 3OMHA 3QCHA 4ZN5A 1FQ1A 4IKCA 1Q6PA 4WU3A 1L8KA 1PTUA 3RZ2A 2CM7A 2I4EA 1L8GA 4HJQA 4RI4A 2F6YA 2NTAA 2QBRA 3QCCA 4Z6BA 3O3LA 2F6TA 4GS0A 2GJTA 3F81A 3N0AA 4D3QA 1I57A 2H03A 2H4VA 3MOWA 2OOQA 4RKKA 5K25A 2PQ5A 2FJMA 3GXGA 3BRHA 4QUNA 4NWFA 4WOHA 3I80A 1GG4A 3AWFA 2G59A 2E0TA 5K9WA 2OUDA 1NO6A 5KA9A 5KA1A 5K22A 1V3AA 2AHSA 4CVLA 4GFUA 3QCGA 4PVGA 2F6WA 3V0GA 2IMGA 3O4UA 1I9TA 2I3RA 2X5OA 1JBVA 2HNPA 1C87A 1PTYA 4QBWA 4KYQA 4CVKA 4Y2EA 4ZI4A 4QAHA 5K23A 1WAXA 2WJPA 3ZM3A 3S3FA 1BZJA 1LQFA 2XJAA 3RGQA 1T4JA 2VORA 2PA5A 2UUOA 2F46A 5KA8A 1E8CA 5A5FA 1BZCA 2C7SA 5KAAA 3ZM5A 2NLKA 1NZ7A 2I4HA 3ZMPA 1Q6SA 2VOSA 2HC1A 2GCBA 3S3EA 2CNGA 2QBPA 5KA4A 2I6MA 2Y68A 2OZ5A 1PYNA 2A8BA 4BPCA 1WCHA 3ZM0A 4OHHA 1NWLA 3D9CA 3O4SA 1P31A 1FPZA 1OEUA 5KADA 1LYVA 4J51A 1PTTA 3QKPA 4OHLA 3LJ8A 2BV5A 4HRFA 5IBMA 1ZC0A 3I36A 4I8NA 1KAVA 3V0FA 4RH5A 1YN9A 2F6VA 2I6PA 1ONYA 4OHEA 3NRSA 1A5YA 2R0BA 2BGEA 2HY3A 1C88A 2J16B 5MMZB 4OHIA 4GRYA 2CMBA 2QDCA 2HXPA 2Y96A 2CM3A 3QCFA 3I7ZA 1YPTA 2CMCA 2AM1A 1X24A 5J8RA 2F71A 4H1OA 4RHGA 3N2AA 3EMUA 5K9VA 1GWZA 3M4UA 2UUPA 3H2XA 2NZ6A 4Y14A 3QCBA 2G6ZA 2CFVA 1Q6JA 2B3OA 2CNEA 2M3VA 3GXHA 2XPCA 1G1HA 3O5XA 2I5XA 4WU2A 2CNIA 1JLNA 3EU0A 3ZMQA 1ZCLA 1YTNA 2CM8A 2PI7A 2WGPA 2Q05A 2AZRA 2OC3A 1OHDA 2HVLA 5EHRA 3NMEA 2Y67A 1XM2A 1YTSA 3V0JA 2P4DA 1U24A 5AWXA 1RXDA 5BZXA 5LXQB 4ZRTA 3ZV2A 2RF6A 1YFOA 3QCZA 4UAGA 1R6HA 4AZ1A 2QBSA 3A5KA 4CVMA 3AWGA 2BGDA 2CJZA 2FH7A 3UAGA 3EZZA 3QCDA 4BJOA 3QKQA 3EB1A 2ZN7A 1NNYA 4GE5A 3D1OA 4BUCA 5GTJA 4C13A 1OHCA 3ZM6A 1T49A 4BUBA 5KA2A 5KA7A 1OEMX 2GC5A 4GE2A 4R0SA 1EEHA 5K24A 4JMJA 1G7FA 3MOZA 2VEVA 4GE6A 2A3KA 1FGSA 2H02A 2GWOA 5BZZA 4YR8B 3S4EA 1RPMA 5BX1A 1C86A 1PXHA 3ZM1A 2HNQA 1G1FA 2H4KA 1I9SA 2J17A 3HN7A 2JFHA 2VTDA 2I6IA 3LK7A 2JFFA 2MBCA 3BLTA 2UAGA 3BLUA 2BZLA 3ZM2A 1OESA 4OHDA 1OETA 3BM8A 3A5JA 3OLRA 4B04A 1Q6MA 3MMJA 4GWFA 4MBBA 1Q6NA 4HJPA 2H04A 5A5EA 1OEOX 2CNHA 2I42A 3V0HA 1AAXA 3V0DA 2FJNA 3PS5A 3D44A 1M3GA 2GP0A 1U26A 2HCMA 2CNFA 2GC6A 2B07A 4NX8A 1OEVA 3S3KA 2HC2A 1XRIA 3F99A 4QDIA 3MVNA 3QCMA 4QUMA 2Q47A 3EAXA 3U96A 1YGRA 2B4PA 3QCLA 1C83A 2JFGA 3B7OA 2B4UA 2NT2A 1XXPA 1MKPA 1XXVA 4HV4A 4NWGA 1J4XA 1JF7A 4H34A 1PTVA 2P6XA 2B4SA 2WTZA 5KA3A 1ZCKA 4KYRA 1FPRA 1W7KA 1XBOA 2ESBA 2VEXA 3D42A 4S0GA 1T48A 1BZHA 1D5RA 3QCNA 2Y66A 1PA9A 2C46A 3F9AA 1GQYA 3V0EA 1KAKA 2Y2FA 3S3HA 2B4OA 3CM3A 2NT7A 5BUGA 3F41A 2J16A 4RH9A 2Y1OA 2QDPA 1EENA 3D1HA 1YZ4A 4NYHA 1PA1A 3S4OA 5KA0A 4QAPA 2JJDA 4GFVA 4R0TA 4TVVA 4YAAA 3D1QA 2B49A 4D3PA
chains in the Genus database with same CATH topology
2PBNA 1OHEA 2H4GA 3O4TA 1QZ0A 1EEOA 1G7GA 4JBCA 4WTYA 2QDMA 4RDDA 1ECVA 1SUGA 1U25A 1C84A 2DXPA 4DGPA 2BIJA 2I6JA 2PSZA 1LARA 2F70A 2I3UA 1Q6TA 4PYHA 5I6VA 4GRZA 1VHRA 2I6OA 5M43A 1GFYA 2PT0A 2SHPA 5KABA 2CM2A 3RGOA 1YWFA 1G1GA 4D3RA 5IBSA 5EHPA 2ZMMA 3CWEA 3QCIA 4R30A 3SR9A 4DGXA 3F9BA 1G4US 3SMEA 2YDUA 5KACA 4ICZA 4NNDA 3QCEA 4RI5A 1ONZA 2VEYA 2HB1A 2QEPA 4JNBA 4QBEA 3AWEA 1YGUA 2I1YA 2I4GA 2I75A 3RO1A 2F6FA 1C85A 3QCKA 1Q1MA 2NV5A 2QCJA 5HDEA 1NWEA 4ERCA 1G4WR 1P15A 2VEWA 3QCJA 1QXKA 4KI9A 1PH0A 4JMKA 2QBQA 2F6ZA 3V0IA 1WRMA 2VEUA 1NL9A 2CMAA 2QCTA 1ZZWA 1YTWA 3OMHA 3QCHA 4ZN5A 1FQ1A 4IKCA 1Q6PA 4WU3A 1L8KA 1PTUA 3RZ2A 2CM7A 2I4EA 1L8GA 4HJQA 4RI4A 2F6YA 2NTAA 2QBRA 3QCCA 4Z6BA 3O3LA 2F6TA 4GS0A 2GJTA 3F81A 3N0AA 4D3QA 1I57A 2H03A 2H4VA 3MOWA 2OOQA 4RKKA 5K25A 2PQ5A 2FJMA 3GXGA 3BRHA 4QUNA 4NWFA 4WOHA 3I80A 3AWFA 2G59A 2E0TA 5K9WA 2OUDA 1NO6A 5KA9A 5KA1A 5K22A 1V3AA 2AHSA 4GFUA 3QCGA 4PVGA 2F6WA 3V0GA 2IMGA 3O4UA 1I9TA 2I3RA 2HNPA 1C87A 1PTYA 4QBWA 4KYQA 4ZI4A 4Y2EA 4QAHA 5K23A 1WAXA 3ZM3A 3S3FA 1BZJA 1LQFA 3RGQA 1T4JA 2PA5A 2F46A 5KA8A 1BZCA 2C7SA 5KAAA 2NLKA 1NZ7A 2I4HA 3ZMPA 1Q6SA 2HC1A 3S3EA 2CNGA 2QBPA 5KA4A 2I6MA 2OZ5A 1PYNA 2A8BA 4BPCA 1WCHA 3ZM0A 4OHHA 1NWLA 3D9CA 3O4SA 1FPZA 1OEUA 5KADA 1LYVA 4J51A 1PTTA 3QKPA 4OHLA 3LJ8A 2BV5A 4HRFA 5IBMA 1ZC0A 3I36A 4I8NA 1KAVA 3V0FA 4RH5A 1YN9A 2F6VA 2I6PA 1ONYA 4OHEA 1A5YA 2R0BA 2BGEA 2HY3A 1C88A 2J16B 5MMZB 4OHIA 4GRYA 2CMBA 2QDCA 2HXPA 2Y96A 2CM3A 3QCFA 3I7ZA 1YPTA 2CMCA 1X24A 5J8RA 2F71A 4H1OA 4RHGA 3EMUA 5K9VA 1GWZA 3M4UA 3H2XA 2NZ6A 4Y14A 3QCBA 2G6ZA 2CFVA 1Q6JA 2B3OA 2CNEA 2M3VA 3GXHA 1G1HA 3O5XA 2I5XA 4WU2A 2CNIA 1JLNA 3EU0A 3ZMQA 1ZCLA 1YTNA 2CM8A 2PI7A 2WGPA 2Q05A 2AZRA 2OC3A 1OHDA 2HVLA 5EHRA 3NMEA 1XM2A 1YTSA 3V0JA 2P4DA 1U24A 5AWXA 1RXDA 5BZXA 5LXQB 4ZRTA 3ZV2A 2RF6A 1YFOA 1R6HA 4AZ1A 2QBSA 3A5KA 3AWGA 2BGDA 2CJZA 2FH7A 3EZZA 3QCDA 4BJOA 3QKQA 3EB1A 2ZN7A 1NNYA 4GE5A 3D1OA 5GTJA 1OHCA 1T49A 5KA2A 5KA7A 1OEMX 4GE2A 4R0SA 5K24A 4JMJA 1G7FA 3MOZA 2VEVA 4GE6A 2A3KA 2H02A 2GWOA 5BZZA 4YR8B 3S4EA 1RPMA 5BX1A 1C86A 1PXHA 3ZM1A 2HNQA 1G1FA 2H4KA 1I9SA 2J17A 2I6IA 2MBCA 3BLTA 3BLUA 2BZLA 3ZM2A 1OESA 4OHDA 1OETA 3BM8A 3A5JA 3OLRA 4B04A 1Q6MA 3MMJA 4GWFA 4MBBA 1Q6NA 4HJPA 2H04A 1OEOX 2CNHA 2I42A 3V0HA 1AAXA 3V0DA 2FJNA 3PS5A 3D44A 1M3GA 2GP0A 1U26A 2HCMA 2CNFA 2B07A 4NX8A 1OEVA 3S3KA 2HC2A 1XRIA 3F99A 3QCMA 4QUMA 2Q47A 3EAXA 3U96A 1YGRA 2B4PA 3QCLA 1C83A 3B7OA 2B4UA 2NT2A 1XXPA 1MKPA 1XXVA 4NWGA 1J4XA 1JF7A 4H34A 1PTVA 2P6XA 2B4SA 5KA3A 1ZCKA 4KYRA 1FPRA 2ESBA 1XBOA 2VEXA 3D42A 4S0GA 1T48A 1BZHA 1D5RA 3QCNA 1PA9A 2C46A 3F9AA 3V0EA 1KAKA 2Y2FA 3S3HA 2B4OA 3CM3A 2NT7A 5BUGA 3F41A 2J16A 4RH9A 2QDPA 1EENA 3D1HA 1YZ4A 4NYHA 1PA1A 3S4OA 5KA0A 4QAPA 2JJDA 4GFVA 4R0TA 4TVVA 4YAAA 3D1QA 2B49A 4D3PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PBN A;  1OHE A;  2H4G A;  3O4T A;  1QZ0 A;  1EEO A;  1G7G A;  4JBC A;  4WTY A;  2QDM A;  4RDD A;  1ECV A;  1SUG A;  1U25 A;  1C84 A;  2DXP A;  4DGP A;  2BIJ A;  2I6J A;  2PSZ A;  1LAR A;  2F70 A;  2I3U A;  1Q6T A;  4PYH A;  5I6V A;  4GRZ A;  1VHR A;  2I6O A;  5M43 A;  1GFY A;  2PT0 A;  2SHP A;  5KAB A;  2CM2 A;  3RGO A;  1YWF A;  1G1G A;  4D3R A;  5IBS A;  5EHP A;  2ZMM A;  3CWE A;  3QCI A;  4R30 A;  3SR9 A;  4DGX A;  3F9B A;  1G4U S;  3SME A;  2YDU A;  5KAC A;  4ICZ A;  4NND A;  3QCE A;  4RI5 A;  1ONZ A;  2VEY A;  2HB1 A;  2QEP A;  4JNB A;  4QBE A;  3AWE A;  1YGU A;  2I1Y A;  2I4G A;  2I75 A;  3RO1 A;  2F6F A;  1C85 A;  3QCK A;  1Q1M A;  2NV5 A;  2QCJ A;  5HDE A;  1NWE A;  4ERC A;  1G4W R;  1P15 A;  2VEW A;  3QCJ A;  1QXK A;  4KI9 A;  1PH0 A;  4JMK A;  2QBQ A;  2F6Z A;  3V0I A;  1WRM A;  2VEU A;  1NL9 A;  2CMA A;  2QCT A;  1ZZW A;  1YTW A;  3OMH A;  3QCH A;  4ZN5 A;  1FQ1 A;  4IKC A;  1Q6P A;  4WU3 A;  1L8K A;  1PTU A;  3RZ2 A;  2CM7 A;  2I4E A;  1L8G A;  4HJQ A;  4RI4 A;  2F6Y A;  2NTA A;  2QBR A;  3QCC A;  4Z6B A;  3O3L A;  2F6T A;  4GS0 A;  2GJT A;  3F81 A;  3N0A A;  4D3Q A;  1I57 A;  2H03 A;  2H4V A;  3MOW A;  2OOQ A;  4RKK A;  5K25 A;  2PQ5 A;  2FJM A;  3GXG A;  3BRH A;  4QUN A;  4NWF A;  4WOH A;  3I80 A;  3AWF A;  2G59 A;  2E0T A;  5K9W A;  2OUD A;  1NO6 A;  5KA9 A;  5KA1 A;  5K22 A;  1V3A A;  2AHS A;  4GFU A;  3QCG A;  4PVG A;  2F6W A;  3V0G A;  2IMG A;  3O4U A;  1I9T A;  2I3R A;  2HNP A;  1C87 A;  1PTY A;  4QBW A;  4KYQ A;  4ZI4 A;  4Y2E A;  4QAH A;  5K23 A;  1WAX A;  3ZM3 A;  3S3F A;  1BZJ A;  1LQF A;  3RGQ A;  1T4J A;  2PA5 A;  2F46 A;  5KA8 A;  1BZC A;  2C7S A;  5KAA A;  2NLK A;  1NZ7 A;  2I4H A;  3ZMP A;  1Q6S A;  2HC1 A;  3S3E A;  2CNG A;  2QBP A;  5KA4 A;  2I6M A;  2OZ5 A;  1PYN A;  2A8B A;  4BPC A;  1WCH A;  3ZM0 A;  4OHH A;  1NWL A;  3D9C A;  3O4S A;  1FPZ A;  1OEU A;  5KAD A;  1LYV A;  4J51 A;  1PTT A;  3QKP A;  4OHL A;  3LJ8 A;  2BV5 A;  4HRF A;  5IBM A;  1ZC0 A;  3I36 A;  4I8N A;  1KAV A;  3V0F A;  4RH5 A;  1YN9 A;  2F6V A;  2I6P A;  1ONY A;  4OHE A;  1A5Y A;  2R0B A;  2BGE A;  2HY3 A;  1C88 A;  2J16 B;  5MMZ B;  4OHI A;  4GRY A;  2CMB A;  2QDC A;  2HXP A;  2Y96 A;  2CM3 A;  3QCF A;  3I7Z A;  1YPT A;  2CMC A;  1X24 A;  5J8R A;  2F71 A;  4H1O A;  4RHG A;  3EMU A;  5K9V A;  1GWZ A;  3M4U A;  3H2X A;  2NZ6 A;  4Y14 A;  3QCB A;  2G6Z A;  2CFV A;  1Q6J A;  2B3O A;  2CNE A;  2M3V A;  3GXH A;  1G1H A;  3O5X A;  2I5X A;  4WU2 A;  2CNI A;  1JLN A;  3EU0 A;  3ZMQ A;  1ZCL A;  1YTN A;  2CM8 A;  2PI7 A;  2WGP A;  2Q05 A;  2AZR A;  2OC3 A;  1OHD A;  2HVL A;  5EHR A;  3NME A;  1XM2 A;  1YTS A;  3V0J A;  2P4D A;  1U24 A;  5AWX A;  1RXD A;  5BZX A;  5LXQ B;  4ZRT A;  3ZV2 A;  2RF6 A;  1YFO A;  1R6H A;  4AZ1 A;  2QBS A;  3A5K A;  3AWG A;  2BGD A;  2CJZ A;  2FH7 A;  3EZZ A;  3QCD A;  4BJO A;  3QKQ A;  3EB1 A;  2ZN7 A;  1NNY A;  4GE5 A;  3D1O A;  5GTJ A;  1OHC A;  1T49 A;  5KA2 A;  5KA7 A;  1OEM X;  4GE2 A;  4R0S A;  5K24 A;  4JMJ A;  1G7F A;  3MOZ A;  2VEV A;  4GE6 A;  2A3K A;  2H02 A;  2GWO A;  5BZZ A;  4YR8 B;  3S4E A;  1RPM A;  5BX1 A;  1C86 A;  1PXH A;  3ZM1 A;  2HNQ A;  1G1F A;  2H4K A;  1I9S A;  2J17 A;  2I6I A;  2MBC A;  3BLT A;  3BLU A;  2BZL A;  3ZM2 A;  1OES A;  4OHD A;  1OET A;  3BM8 A;  3A5J A;  3OLR A;  4B04 A;  1Q6M A;  3MMJ A;  4GWF A;  4MBB A;  1Q6N A;  4HJP A;  2H04 A;  1OEO X;  2CNH A;  2I42 A;  3V0H A;  1AAX A;  3V0D A;  2FJN A;  3PS5 A;  3D44 A;  1M3G A;  2GP0 A;  1U26 A;  2HCM A;  2CNF A;  2B07 A;  4NX8 A;  1OEV A;  3S3K A;  2HC2 A;  1XRI A;  3F99 A;  3QCM A;  4QUM A;  2Q47 A;  3EAX A;  3U96 A;  1YGR A;  2B4P A;  3QCL A;  1C83 A;  3B7O A;  2B4U A;  2NT2 A;  1XXP A;  1MKP A;  1XXV A;  4NWG A;  1J4X A;  1JF7 A;  4H34 A;  1PTV A;  2P6X A;  2B4S A;  5KA3 A;  1ZCK A;  4KYR A;  1FPR A;  2ESB A;  1XBO A;  2VEX A;  3D42 A;  4S0G A;  1T48 A;  1BZH A;  1D5R A;  3QCN A;  1PA9 A;  2C46 A;  3F9A A;  3V0E A;  1KAK A;  2Y2F A;  3S3H A;  2B4O A;  3CM3 A;  2NT7 A;  5BUG A;  3F41 A;  2J16 A;  4RH9 A;  2QDP A;  1EEN A;  3D1H A;  1YZ4 A;  4NYH A;  1PA1 A;  3S4O A;  5KA0 A;  4QAP A;  2JJD A;  4GFV A;  4R0T A;  4TVV A;  4YAA A;  3D1Q A;  2B49 A;  4D3P A; 
#chains in the Genus database with same CATH topology
 2PBN A;  1OHE A;  2H4G A;  3O4T A;  1QZ0 A;  1EEO A;  1G7G A;  1P3D A;  4JBC A;  4WTY A;  2QDM A;  4RDD A;  4ZIY A;  1ECV A;  1SUG A;  1U25 A;  1C84 A;  2DXP A;  2F00 A;  4DGP A;  2BIJ A;  4QF5 A;  2I6J A;  2PSZ A;  1LAR A;  2F70 A;  2I3U A;  1Q6T A;  4PYH A;  1GQQ A;  5I6V A;  4GRZ A;  1VHR A;  2I6O A;  5M43 A;  1GFY A;  2PT0 A;  2SHP A;  2VTE A;  5KAB A;  2CM2 A;  3RGO A;  1YWF A;  1G1G A;  4D3R A;  5IBS A;  5EHP A;  2ZMM A;  3CWE A;  3QCI A;  4R30 A;  3SR9 A;  4DGX A;  3F9B A;  1G4U S;  3SME A;  2YDU A;  1W78 A;  5KAC A;  4ICZ A;  1O5Z A;  1UAG A;  4NND A;  3ZL8 A;  3QCE A;  4RI5 A;  1ONZ A;  2VEY A;  2HB1 A;  2QEP A;  3PYZ A;  4JNB A;  4QBE A;  3AWE A;  1YGU A;  2I1Y A;  1J6U A;  1E0D A;  2I4G A;  2I75 A;  3RO1 A;  2F6F A;  1C85 A;  2NV5 A;  2QCJ A;  1Q1M A;  2GCA A;  3QCK A;  5HDE A;  1NWE A;  4ERC A;  1G4W R;  1P15 A;  2VEW A;  3QCJ A;  1QXK A;  4KI9 A;  1PH0 A;  4JMK A;  1JBW A;  2QBQ A;  2F6Z A;  3V0I A;  2AM2 A;  1WRM A;  4C12 A;  2VEU A;  1NL9 A;  2CMA A;  2QCT A;  1ZZW A;  1YTW A;  3OMH A;  3QCH A;  4ZN5 A;  1FQ1 A;  4IKC A;  1Q6P A;  4WU3 A;  1L8K A;  1PTU A;  3RZ2 A;  2CM7 A;  2I4E A;  1L8G A;  4HJQ A;  4RI4 A;  2F6Y A;  2NTA A;  2QBR A;  3QCC A;  4Z6B A;  3O3L A;  2F6T A;  4GS0 A;  2GJT A;  3F81 A;  3N0A A;  4D3Q A;  1I57 A;  2H03 A;  2H4V A;  3MOW A;  2OOQ A;  4RKK A;  5K25 A;  2PQ5 A;  2FJM A;  3GXG A;  3BRH A;  4QUN A;  4NWF A;  4WOH A;  3I80 A;  1GG4 A;  3AWF A;  2G59 A;  2E0T A;  5K9W A;  2OUD A;  1NO6 A;  5KA9 A;  5KA1 A;  5K22 A;  1V3A A;  2AHS A;  4CVL A;  4GFU A;  3QCG A;  4PVG A;  2F6W A;  3V0G A;  2IMG A;  3O4U A;  1I9T A;  2I3R A;  2X5O A;  1JBV A;  2HNP A;  1C87 A;  1PTY A;  4QBW A;  4KYQ A;  4CVK A;  4Y2E A;  4ZI4 A;  4QAH A;  5K23 A;  1WAX A;  2WJP A;  3ZM3 A;  3S3F A;  1BZJ A;  1LQF A;  2XJA A;  3RGQ A;  1T4J A;  2VOR A;  2PA5 A;  2UUO A;  2F46 A;  5KA8 A;  1E8C A;  5A5F A;  1BZC A;  2C7S A;  5KAA A;  3ZM5 A;  2NLK A;  1NZ7 A;  2I4H A;  3ZMP A;  1Q6S A;  2VOS A;  2HC1 A;  2GCB A;  3S3E A;  2CNG A;  2QBP A;  5KA4 A;  2I6M A;  2Y68 A;  2OZ5 A;  1PYN A;  2A8B A;  4BPC A;  1WCH A;  3ZM0 A;  4OHH A;  1NWL A;  3D9C A;  3O4S A;  1P31 A;  1FPZ A;  1OEU A;  5KAD A;  1LYV A;  4J51 A;  1PTT A;  3QKP A;  4OHL A;  3LJ8 A;  2BV5 A;  4HRF A;  5IBM A;  1ZC0 A;  3I36 A;  4I8N A;  1KAV A;  3V0F A;  4RH5 A;  1YN9 A;  2F6V A;  2I6P A;  1ONY A;  4OHE A;  3NRS A;  1A5Y A;  2R0B A;  2BGE A;  2HY3 A;  1C88 A;  2J16 B;  5MMZ B;  4OHI A;  4GRY A;  2CMB A;  2QDC A;  2HXP A;  2Y96 A;  2CM3 A;  3QCF A;  3I7Z A;  1YPT A;  2CMC A;  2AM1 A;  1X24 A;  5J8R A;  2F71 A;  4H1O A;  4RHG A;  3N2A A;  3EMU A;  5K9V A;  1GWZ A;  3M4U A;  2UUP A;  3H2X A;  2NZ6 A;  4Y14 A;  3QCB A;  2G6Z A;  2CFV A;  1Q6J A;  2B3O A;  2CNE A;  2M3V A;  3GXH A;  2XPC A;  1G1H A;  3O5X A;  2I5X A;  4WU2 A;  2CNI A;  1JLN A;  3EU0 A;  3ZMQ A;  1ZCL A;  1YTN A;  2CM8 A;  2PI7 A;  2WGP A;  2Q05 A;  2AZR A;  2OC3 A;  1OHD A;  2HVL A;  5EHR A;  3NME A;  2Y67 A;  1XM2 A;  1YTS A;  3V0J A;  2P4D A;  1U24 A;  5AWX A;  1RXD A;  5BZX A;  5LXQ B;  4ZRT A;  3ZV2 A;  2RF6 A;  1YFO A;  3QCZ A;  4UAG A;  1R6H A;  4AZ1 A;  2QBS A;  3A5K A;  4CVM A;  3AWG A;  2BGD A;  2CJZ A;  2FH7 A;  3UAG A;  3EZZ A;  3QCD A;  4BJO A;  3QKQ A;  3EB1 A;  2ZN7 A;  1NNY A;  4GE5 A;  3D1O A;  4BUC A;  5GTJ A;  4C13 A;  1OHC A;  3ZM6 A;  1T49 A;  4BUB A;  5KA2 A;  5KA7 A;  1OEM X;  2GC5 A;  4GE2 A;  4R0S A;  1EEH A;  5K24 A;  4JMJ A;  1G7F A;  3MOZ A;  2VEV A;  4GE6 A;  2A3K A;  1FGS A;  2H02 A;  2GWO A;  5BZZ A;  4YR8 B;  3S4E A;  1RPM A;  5BX1 A;  1C86 A;  1PXH A;  3ZM1 A;  2HNQ A;  1G1F A;  2H4K A;  1I9S A;  2J17 A;  3HN7 A;  2JFH A;  2VTD A;  2I6I A;  3LK7 A;  2JFF A;  2MBC A;  3BLT A;  2UAG A;  3BLU A;  2BZL A;  3ZM2 A;  1OES A;  4OHD A;  1OET A;  3BM8 A;  3A5J A;  3OLR A;  4B04 A;  1Q6M A;  3MMJ A;  4GWF A;  4MBB A;  1Q6N A;  4HJP A;  2H04 A;  5A5E A;  1OEO X;  2CNH A;  2I42 A;  3V0H A;  1AAX A;  3V0D A;  2FJN A;  3PS5 A;  3D44 A;  1M3G A;  2GP0 A;  1U26 A;  2HCM A;  2CNF A;  2GC6 A;  2B07 A;  4NX8 A;  1OEV A;  3S3K A;  2HC2 A;  1XRI A;  3F99 A;  4QDI A;  3MVN A;  3QCM A;  4QUM A;  2Q47 A;  3EAX A;  3U96 A;  1YGR A;  2B4P A;  3QCL A;  1C83 A;  2JFG A;  3B7O A;  2B4U A;  2NT2 A;  1XXP A;  1MKP A;  1XXV A;  4HV4 A;  4NWG A;  1J4X A;  1JF7 A;  4H34 A;  1PTV A;  2P6X A;  2B4S A;  2WTZ A;  5KA3 A;  1ZCK A;  4KYR A;  1FPR A;  1W7K A;  1XBO A;  2ESB A;  2VEX A;  3D42 A;  4S0G A;  1T48 A;  1BZH A;  1D5R A;  3QCN A;  2Y66 A;  1PA9 A;  2C46 A;  3F9A A;  1GQY A;  3V0E A;  1KAK A;  2Y2F A;  3S3H A;  2B4O A;  3CM3 A;  2NT7 A;  5BUG A;  3F41 A;  2J16 A;  4RH9 A;  2Y1O A;  2QDP A;  1EEN A;  3D1H A;  1YZ4 A;  4NYH A;  1PA1 A;  3S4O A;  5KA0 A;  4QAP A;  2JJD A;  4GFV A;  4R0T A;  4TVV A;  4YAA A;  3D1Q A;  2B49 A;  4D3P A; 
#chains in the Genus database with same CATH homology
 2PBN A;  1OHE A;  2H4G A;  3O4T A;  1QZ0 A;  1EEO A;  1G7G A;  4JBC A;  4WTY A;  2QDM A;  4RDD A;  1ECV A;  1SUG A;  1U25 A;  1C84 A;  2DXP A;  4DGP A;  2BIJ A;  2I6J A;  2PSZ A;  1LAR A;  2F70 A;  2I3U A;  1Q6T A;  4PYH A;  5I6V A;  4GRZ A;  1VHR A;  2I6O A;  5M43 A;  1GFY A;  2PT0 A;  2SHP A;  5KAB A;  2CM2 A;  3RGO A;  1YWF A;  1G1G A;  4D3R A;  5IBS A;  5EHP A;  2ZMM A;  3CWE A;  3QCI A;  4R30 A;  3SR9 A;  4DGX A;  3F9B A;  1G4U S;  3SME A;  2YDU A;  5KAC A;  4ICZ A;  4NND A;  3QCE A;  4RI5 A;  1ONZ A;  2VEY A;  2HB1 A;  2QEP A;  4JNB A;  4QBE A;  3AWE A;  1YGU A;  2I1Y A;  2I4G A;  2I75 A;  3RO1 A;  2F6F A;  1C85 A;  3QCK A;  1Q1M A;  2NV5 A;  2QCJ A;  5HDE A;  1NWE A;  4ERC A;  1G4W R;  1P15 A;  2VEW A;  3QCJ A;  1QXK A;  4KI9 A;  1PH0 A;  4JMK A;  2QBQ A;  2F6Z A;  3V0I A;  1WRM A;  2VEU A;  1NL9 A;  2CMA A;  2QCT A;  1ZZW A;  1YTW A;  3OMH A;  3QCH A;  4ZN5 A;  1FQ1 A;  4IKC A;  1Q6P A;  4WU3 A;  1L8K A;  1PTU A;  3RZ2 A;  2CM7 A;  2I4E A;  1L8G A;  4HJQ A;  4RI4 A;  2F6Y A;  2NTA A;  2QBR A;  3QCC A;  4Z6B A;  3O3L A;  2F6T A;  4GS0 A;  2GJT A;  3F81 A;  3N0A A;  4D3Q A;  1I57 A;  2H03 A;  2H4V A;  3MOW A;  2OOQ A;  4RKK A;  5K25 A;  2PQ5 A;  2FJM A;  3GXG A;  3BRH A;  4QUN A;  4NWF A;  4WOH A;  3I80 A;  3AWF A;  2G59 A;  2E0T A;  5K9W A;  2OUD A;  1NO6 A;  5KA9 A;  5KA1 A;  5K22 A;  1V3A A;  2AHS A;  4GFU A;  3QCG A;  4PVG A;  2F6W A;  3V0G A;  2IMG A;  3O4U A;  1I9T A;  2I3R A;  2HNP A;  1C87 A;  1PTY A;  4QBW A;  4KYQ A;  4ZI4 A;  4Y2E A;  4QAH A;  5K23 A;  1WAX A;  3ZM3 A;  3S3F A;  1BZJ A;  1LQF A;  3RGQ A;  1T4J A;  2PA5 A;  2F46 A;  5KA8 A;  1BZC A;  2C7S A;  5KAA A;  2NLK A;  1NZ7 A;  2I4H A;  3ZMP A;  1Q6S A;  2HC1 A;  3S3E A;  2CNG A;  2QBP A;  5KA4 A;  2I6M A;  2OZ5 A;  1PYN A;  2A8B A;  4BPC A;  1WCH A;  3ZM0 A;  4OHH A;  1NWL A;  3D9C A;  3O4S A;  1FPZ A;  1OEU A;  5KAD A;  1LYV A;  4J51 A;  1PTT A;  3QKP A;  4OHL A;  3LJ8 A;  2BV5 A;  4HRF A;  5IBM A;  1ZC0 A;  3I36 A;  4I8N A;  1KAV A;  3V0F A;  4RH5 A;  1YN9 A;  2F6V A;  2I6P A;  1ONY A;  4OHE A;  1A5Y A;  2R0B A;  2BGE A;  2HY3 A;  1C88 A;  2J16 B;  5MMZ B;  4OHI A;  4GRY A;  2CMB A;  2QDC A;  2HXP A;  2Y96 A;  2CM3 A;  3QCF A;  3I7Z A;  1YPT A;  2CMC A;  1X24 A;  5J8R A;  2F71 A;  4H1O A;  4RHG A;  3EMU A;  5K9V A;  1GWZ A;  3M4U A;  3H2X A;  2NZ6 A;  4Y14 A;  3QCB A;  2G6Z A;  2CFV A;  1Q6J A;  2B3O A;  2CNE A;  2M3V A;  3GXH A;  1G1H A;  3O5X A;  2I5X A;  4WU2 A;  2CNI A;  1JLN A;  3EU0 A;  3ZMQ A;  1ZCL A;  1YTN A;  2CM8 A;  2PI7 A;  2WGP A;  2Q05 A;  2AZR A;  2OC3 A;  1OHD A;  2HVL A;  5EHR A;  3NME A;  1XM2 A;  1YTS A;  3V0J A;  2P4D A;  1U24 A;  5AWX A;  1RXD A;  5BZX A;  5LXQ B;  4ZRT A;  3ZV2 A;  2RF6 A;  1YFO A;  1R6H A;  4AZ1 A;  2QBS A;  3A5K A;  3AWG A;  2BGD A;  2CJZ A;  2FH7 A;  3EZZ A;  3QCD A;  4BJO A;  3QKQ A;  3EB1 A;  2ZN7 A;  1NNY A;  4GE5 A;  3D1O A;  5GTJ A;  1OHC A;  1T49 A;  5KA2 A;  5KA7 A;  1OEM X;  4GE2 A;  4R0S A;  5K24 A;  4JMJ A;  1G7F A;  3MOZ A;  2VEV A;  4GE6 A;  2A3K A;  2H02 A;  2GWO A;  5BZZ A;  4YR8 B;  3S4E A;  1RPM A;  5BX1 A;  1C86 A;  1PXH A;  3ZM1 A;  2HNQ A;  1G1F A;  2H4K A;  1I9S A;  2J17 A;  2I6I A;  2MBC A;  3BLT A;  3BLU A;  2BZL A;  3ZM2 A;  1OES A;  4OHD A;  1OET A;  3BM8 A;  3A5J A;  3OLR A;  4B04 A;  1Q6M A;  3MMJ A;  4GWF A;  4MBB A;  1Q6N A;  4HJP A;  2H04 A;  1OEO X;  2CNH A;  2I42 A;  3V0H A;  1AAX A;  3V0D A;  2FJN A;  3PS5 A;  3D44 A;  1M3G A;  2GP0 A;  1U26 A;  2HCM A;  2CNF A;  2B07 A;  4NX8 A;  1OEV A;  3S3K A;  2HC2 A;  1XRI A;  3F99 A;  3QCM A;  4QUM A;  2Q47 A;  3EAX A;  3U96 A;  1YGR A;  2B4P A;  3QCL A;  1C83 A;  3B7O A;  2B4U A;  2NT2 A;  1XXP A;  1MKP A;  1XXV A;  4NWG A;  1J4X A;  1JF7 A;  4H34 A;  1PTV A;  2P6X A;  2B4S A;  5KA3 A;  1ZCK A;  4KYR A;  1FPR A;  2ESB A;  1XBO A;  2VEX A;  3D42 A;  4S0G A;  1T48 A;  1BZH A;  1D5R A;  3QCN A;  1PA9 A;  2C46 A;  3F9A A;  3V0E A;  1KAK A;  2Y2F A;  3S3H A;  2B4O A;  3CM3 A;  2NT7 A;  5BUG A;  3F41 A;  2J16 A;  4RH9 A;  2QDP A;  1EEN A;  3D1H A;  1YZ4 A;  4NYH A;  1PA1 A;  3S4O A;  5KA0 A;  4QAP A;  2JJD A;  4GFV A;  4R0T A;  4TVV A;  4YAA A;  3D1Q A;  2B49 A;  4D3P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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